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[Effect
of PS-K on experimental neurogenic tumors in rats induced by ethylnitrosourea]
[Article
in Japanese]
Tokuda
K, Abe H, Aida T, Kaneko S, Tsuru M
The
effect of PS-K as immunomodulator was studied in Fischer rats bearing neurogenic
tumors induced transplacentally by ENU.
114 rats were divided into control and PS-K treated groups.
All rats were subjected to an autopsy at death and all of central nervous system
were examined macroscopically.
Final neurogenic tumor incidence in PS-K treated groups was significantly lower
than that in the control group, but distribution of these neurogenic tumors and
number of neurogenic tumors in a rat remained unchanged between the control and
the each PS-K treated groups.
Survival time of PS-K treated groups did not increase than the control group.
From these experiments, it might be that induction of neurogenic tumors may be
suppressed by administration of PS-K.
PMID:
6510885 [PubMed - indexed for MEDLINE]
Source:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6510885&dopt=Abstract
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