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[Tumor diseases in
families of 600 breast cancer patients with special reference to familial
adenocarcinomatosis and the Li-Fraumeni-/SBLA syndrome]
[Article in German]
Muller H, Mosimann S, Gebhardt M, Scott R, Spycher M, Weber W
Departement Forschung, Basler
Universitats-kliniken, Kantonsspital Basel
In some families breast cancer aggregates as the predominant
site-specific neoplasia and in others in association with defined
malignancies.
In the case of familial adenocarcinomatous (Lynch II-syndrome) it occurs
together mainly with colorectal and endometrial carcinoma whereas in the case of
the Li-Fraumeni/SBLA-syndrome it belongs to a wider spectrum including sarcoma,
brain tumors, lung and laryngeal cancer, leukaemia and adrenocortical
carcinoma.
The occurrence of these malignancies is reported as they were observed in the
families of 600 women suffering from breast cancer.
PMID:
1526835 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1526835
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