Treatment > Tamoxifen


J Neurosurg Sci. 1996 Jun;40(2):129-33. (Case Study)


Abstract

Clinical and radiographic stabilization of intracranial glioblastoma. 
Report of a case treated after surgery with tamoxifen


Mastronardi L, Farah JO, Puzzilli F, Qasho R, Lunardi P

Civilian Hospital of Terni, Italy.

We report the case of a patient with a left temporal-parietal glioblastoma treated with subtotal surgical excision, radiotherapy and chemotherapy, with a single intravenous administration of carboplatin and continuous oral administration of tamoxifen (40 mg/daily). 
Two years after the patient presents a stabilization of clinical and CT picture. 
We discute the possible role of tamoxifen in prolonging the survival of selected patients with intracranial high-grade glioma.

PMID: 9049896 [PubMed - indexed for MEDLINE]

Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9049896



 

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