|
|
Antioxidants
in cancer therapy; their actions and interactions with oncologic therapies
Lamson
DW, Brignall MS
Tahoma
Clinic, Kent, WA, USA
There is
a concern that antioxidants might reduce oxidizing free radicals created by
radiotherapy and some forms of chemotherapy, and thereby decrease the
effectiveness of the therapy.
The question has arisen whether concurrent administration of oral antioxidants
is contraindicated during cancer therapeutics.
Evidence reviewed here demonstrates exogenous antioxidants alone produce
beneficial effects in various cancers, and except for a few specific cases,
animal and human studies demonstrate no reduction of efficacy of chemotherapy or
radiation when given with antioxidants.
In fact, considerable data exists showing increased effectiveness of many cancer
therapeutic agents, as well as a decrease in adverse effects, when given
concurrently with antioxidants.
PMID:
10559547 [PubMed - indexed for MEDLINE]
|
