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Altern Med Rev 1999 Oct;4(5):304-29 (Review Article)
Comment in:
 Altern Med Rev. 1999 Oct;4(5):303.



Abstract

Antioxidants in cancer therapy; their actions and interactions with oncologic therapies

Lamson DW, Brignall MS

Tahoma Clinic, Kent, WA, USA

There is a concern that antioxidants might reduce oxidizing free radicals created by radiotherapy and some forms of chemotherapy, and thereby decrease the effectiveness of the therapy.
The question has arisen whether concurrent administration of oral antioxidants is contraindicated during cancer therapeutics.
Evidence reviewed here demonstrates exogenous antioxidants alone produce beneficial effects in various cancers, and except for a few specific cases, animal and human studies demonstrate no reduction of efficacy of chemotherapy or radiation when given with antioxidants.
In fact, considerable data exists showing increased effectiveness of many cancer therapeutic agents, as well as a decrease in adverse effects, when given concurrently with antioxidants.

PMID: 10559547 [PubMed - indexed for MEDLINE]


Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10559547&dopt=Abstract
PDF Full Text: http://www.thorne.com/altmedrev/.fulltext/4/5/304.pdf


 

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