From: Subject: 131I Radioconjugated Antibodies for the Locoregional Radioimmunotherapy of High-grade Malignant Glioma: Phase I and II Study - Acta Oncologica Date: Sun, 17 Feb 2008 19:40:26 +0100 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0000_01C8719C.F19834A0" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198 This is a multi-part message in MIME format. ------=_NextPart_000_0000_01C8719C.F19834A0 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.informaworld.com/smpp/content~content=a713790806 131I Radioconjugated Antibodies for the = Locoregional Radioimmunotherapy of High-grade Malignant Glioma: Phase I = and II Study - Acta Oncologica
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131I Radioconjugated Antibodies for = the=20 Locoregional Radioimmunotherapy of = High-grade=20 Malignant Glioma: Phase I and II Study =

Authors: Pietro = Riva; =20 Giancarlo Franceschi;  Massimo=20 Frattarelli;  Nada Riva;  = Graziano=20 Guiducci;  Anna Maria = Cremonini; =20 Graziano Giuliani;  Michela = Casi; =20 Rossella Gentile;  Annti A. Jekunen; = Kalevi=20 J. A. Kairemo
DOI: = 10.1080/028418699431438=20
Publication = Frequency: 8=20 issues per year
Published in: Acta Oncologica, Volume = 38, Issue 3 May 1999 , pages 351 - = 359=20
Subject: Oncol= ogy;=20
Formats available: = PDF=20 (English)
You=20 have: =20 FREE ACCESS
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    Abstract

    Locoregional=20 radioimmunotherapy (LR-RIT) was = administered to=20 111 patients (20 were recruited in a = phase I and=20 91 in a phase II study) with malignant = gliomas:=20 1 patient with oligodendroglioma, 7 = patients=20 with anaplastic oligodendroglioma, 2 = with grade=20 II astrocytoma, 10 with anaplastic = astrocytoma=20 and 91 with glioblastoma, amounting to = 58 newly=20 diagnosed and 53 recurrent tumours. The=20 131I-labelled monoclonal = antibodies=20 BC-2 and BC-4 were used in order to = recognize=20 stromal and intracellular glycoprotein = tenascin,=20 an antigen present particularly in = glioblastoma.=20 The patients were enrolled between = February 1990=20 and December 1997 after conventional = therapy.=20 The radiopharmaceutical was injected = directly=20 into the tumour site. Sequential = scintigraphies=20 demonstrated a high and enduring uptake = in the=20 tumour. The mean irradiation dose in the = tumour=20 was 300 Gy per cycle. In the group of 74 = phase=20 II glioblastoma patients the clinical = responses=20 were as follows: 10 patients with stable = disease=20 (SD), 9 with partial responses (PR), 23 = with no=20 evidence of disease (NED) and 1 patient = with=20 complete response (CR). The median = survival was=20 19 months. The response rate (CR+PR+NED) = was=20 17.8% for those patients with bulky = lesions,=20 with a median survival of 17 months, but = 66.6%=20 for patients with small lesions, with a = median=20 survival of 25 months. Better outcomes = were=20 recorded in cases with less aggressive = diseases:=20 oligodendroglioma, anaplastic = oligodendroglioma=20 and anaplastic astrocytoma. We conclude = that=20 fractionated LR-RIT can be safely = performed,=20 with promising results especially in = patients=20 with minimal disease.=20
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*.hidefromprint TR { DISPLAY: none; BORDER-COLLAPSE: collapse } *.hidefromprint TD { DISPLAY: none; BORDER-COLLAPSE: collapse } TD.hidefromprint { DISPLAY: none } A[href] { COLOR: black } ------=_NextPart_000_0000_01C8719C.F19834A0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.informaworld.com/mpp/cache/javascript/content/all/javascript_100.8.2.js =0A= function changelocation(url,anchor)=0A= {=0A= var now =3D new Date();=0A= var milli =3D now.getTime();=0A= var finalurl =3D url + "×tamp=3D" + milli;=0A= if (anchor !=3D "undefined") {=0A= finalurl =3D finalurl + "#" + anchor;=0A= }=0A= window.location =3D finalurl;=0A= }=0A= // this just does a get for the URL but does nothing with it=0A= function markitems(url) {=0A= var randnum =3D Math.floor(Math.random()*99999999); image1 =3D new = Image();=0A= image1.src =3D url+"&zdc=3D"+randnum.toString();=0A= }=0A= function ref_popup(mylink, windowname) {=0A= if (! window.focus) {=0A= return true;=0A= }=0A= var href;=0A= var browHeight, browWidth;=0A= browHeight =3D (screen.height*(1/8));=0A= browWidth =3D (screen.width*(6/8));=0A= if (typeof(mylink) =3D=3D 'string') {=0A= href=3Dmylink;=0A= }=0A= else {=0A= href=3Dmylink.href;=0A= }=0A= newwindow=3Dwindow.open(href, windowname, 'height=3D' + browHeight + = ',width=3D' + browWidth = +',resizable=3Dyes,dependent=3Dyes,left=3D'+((1/8)*screen.width)+',top=3D= '+((6/8)*screen.height)+',scrollbars=3Dyes');=0A= newwindow.focus();=0A= return false;=0A= }=0A= function popup(url,target,width,height) {=0A= if (width =3D=3D "undefined"){=0A= width =3D 550;=0A= }=0A= if (height =3D=3D "undefined"){=0A= height =3D 600;=0A= }=0A= var leftVal =3D (screen.width - width) / 2;=0A= var topVal =3D (screen.height - height) / 2;=0A= var popupwindow =3D window.open(url, target, = 'alwaysRaised=3D1,dependent=3Dyes,innerWidth=3D'+width+',innerHeight=3D'+= height+',menubar=3D0,resizable=3D1,scrollbars=3Dyes,screenX=3D'+leftVal+'= ,left=3D'+leftVal+',screenY=3D'+topVal+',top=3D'+topVal+',status=3D0,tool= bar=3D0');=0A= popupwindow.focus;=0A= }=0A= function openPopup(url,target,width,height) {=0A= if (!width) width =3D 600;=0A= if (!height) height =3D 400;=0A= var leftVal =3D (screen.width - width) / 2;=0A= var topVal =3D (screen.height - height) / 2;=0A= var myPopup =3D = window.open(url,target,'width=3D'+width+',height=3D'+height+',status=3Dno= ,toolbar=3Dno,menubar=3Dno,resizable=3Dyes,scrollbars=3Dyes,screenX=3D'+l= eftVal+',left=3D'+leftVal+',screenY=3D'+topVal+',top=3D'+topVal+'');=0A= if (!myPopup.opener) myPopup.opener =3D self;=0A= myPopup.focus;=0A= }=0A= function UseImage(name, subsection) {=0A= var url =3D = './register~mode=3Dlnf~popup=3Dtrue~useimage=3Dtrue~form=3D'+subsection+'= ~name=3D'+name;=0A= window.open(url, 'useimage', 'width=3D540, height=3D600, = resizable=3Dyes, scrollbars=3Dyes, toolbar=3D0'); return false;=0A= }=0A= function read_phrase() {=0A= if (!domData.isClippable) {=0A= return false;=0A= }=0A= var text =3D "";=0A= if (domData.isNN4) {=0A= text =3D document.getSelection(); }=0A= else if (domData.isIE4up) {=0A= text =3D document.selection.createRange().text; }=0A= else if (domData.isNN6up) {=0A= text =3D window.getSelection();=0A= }=0A= return text;=0A= }=0A= function search_phrase() {=0A= if (!domData.isClippable){=0A= return false;=0A= }=0A= var word =3D read_phrase();=0A= if (word=3D=3D"") { void(word =3D prompt('Enter text to search on using = this site. You can also highlight a word on this web page before = clicking search.',''));=0A= }=0A= if (word){=0A= window.location =3D = "./search~db=3Dall?submit=3Dtrue&first=3D1&term1=3D"+word;=0A= }=0A= }=0A= function search_google_scholar() {=0A= if (!domData.isClippable){=0A= return false;=0A= }=0A= var word =3D read_phrase();=0A= if (word=3D=3D"") { void(word =3D prompt('Enter text to search on using = Google Scholar. You can also highlight a word on this web page before = clicking search.',''));=0A= }=0A= if (word){=0A= window.location =3D "http://scholar.google.com/scholar?q=3D"+word;=0A= }=0A= }=0A= startList =3D function() {=0A= if (document.all && document.getElementById) {=0A= navRoot =3D document.getElementById("nav");=0A= if(navRoot){=0A= for (i=3D0; i=3D 5) && (this.isNN);=0A= this.isIE4up =3D (this.wvshort >=3D 4) && (this.isIE);=0A= this.isIE5Mac =3D (this.isIE4up) && (this.wagent.indexOf("5.0") !=3D -1) = && (this.isMac);=0A= this.isIE6 =3D (this.wagent.indexOf("MSIE 6.0") !=3D -1);=0A= this.isOther =3D (!this.isNN4) && (!this.isIE4up) && (!this.isNN6up) && = (!this.isK);=0A= this.isClippable =3D ((this.isIE4up) || (this.isNN6up)) && (!this.isMac) = && (!this.isK);=0A= } domData =3D new domDetect();=0A= // functions used by the marked list add/remove links=0A= var lastVisibleLayer;=0A= function view(layername,evt) {=0A= if (lastVisibleLayer =3D=3D layername) {=0A= //already visible=0A= return;=0A= }=0A= if (lastVisibleLayer) {=0A= hide(lastVisibleLayer);=0A= lastVisibleLayer =3D "";=0A= }=0A= lastVisibleLayer =3D layername;=0A= var thislayer =3D new getObject(layername);=0A= if (evt) {=0A= var x =3D findXCoord(evt);=0A= thislayer.style.left =3D (x-5)+"px";=0A= var y =3D findYCoord(evt);=0A= thislayer.style.top =3D y+"px";=0A= }=0A= checkLayerOnScreen(layername);=0A= thislayer.style.visibility =3D 'visible';=0A= }=0A= function hide(layername) {=0A= if (lastVisibleLayer =3D=3D layername) {=0A= lastVisibleLayer =3D "";=0A= }=0A= var x =3D new getObject(layername);=0A= x.style.visibility =3D 'hidden';=0A= }=0A= function getObject(name) {=0A= if (document.getElementById) {=0A= this.obj =3D document.getElementById(name);=0A= if (this.obj !=3D null) {=0A= this.style =3D document.getElementById(name).style;=0A= }=0A= }=0A= else if (document.all) {=0A= this.obj =3D document.all[name];=0A= if (this.obj !=3D null) {=0A= this.style =3D document.all[name].style;=0A= }=0A= }=0A= else if (document.layers) {=0A= this.obj =3D document.layers[name];=0A= if (this.obj !=3D null) {=0A= this.style =3D document.layers[name];=0A= }=0A= }=0A= }=0A= function findXCoord(evt) {=0A= if (evt.x) return evt.x;=0A= if (evt.pageX) return evt.pageX;=0A= }=0A= function findYCoord(evt) {=0A= if (evt.y) return evt.y;=0A= if (evt.pageY) return evt.pageY;=0A= }=0A= function divPopulate(divname,data) {=0A= if (document.getElementById) {=0A= document.getElementById(divname).innerHTML =3D data;=0A= }=0A= else if (document.all) {=0A= document.all[divname].innerHTML =3D data;=0A= }=0A= else if (document.layers) {=0A= var d =3D document.layers[divname]; d.document.open();=0A= d.document.writeln(data);=0A= d.document.close();=0A= }=0A= }=0A= function openerDivPopulate(divname,data) {=0A= if (opener.document.getElementById) {=0A= opener.document.getElementById(divname).innerHTML =3D data;=0A= }=0A= else if (opener.document.all) {=0A= opener.document.all[divname].innerHTML =3D data;=0A= }=0A= else if (opener.document.layers) {=0A= var d =3D opener.document.layers[divname]; d.document.open();=0A= d.document.writeln(data);=0A= d.document.close();=0A= }=0A= }=0A= function openerGetDivContents(divname) {=0A= if (opener.document.getElementById) {=0A= var c =3D opener.document.getElementById(divname).innerHTML;=0A= return c;=0A= }=0A= else if (opener.document.all) {=0A= var c =3D opener.document.all[divname].innerHTML;=0A= return c;=0A= }=0A= else if (opener.document.layers) {=0A= var d =3D opener.document.layers[divname]; d.document.open();=0A= was =3D d.document.readln();=0A= d.document.close();=0A= return was;=0A= }=0A= }=0A= function SetAllCheckBoxes(FormName, FieldName, CheckValue) {=0A= if(!document.forms[FormName])=0A= return;=0A= var objCheckBoxes =3D document.forms[FormName].elements[FieldName];=0A= if(!objCheckBoxes) return;=0A= var countCheckBoxes =3D objCheckBoxes.length;=0A= if(!countCheckBoxes)=0A= objCheckBoxes.checked =3D CheckValue;=0A= else=0A= // set the check value for all check boxes=0A= for(var i =3D 0; i < countCheckBoxes; i++)=0A= objCheckBoxes[i].checked =3D CheckValue;=0A= }=0A= function mouseLeaves (element, evt) {=0A= if (typeof evt.toElement !=3D 'undefined' && evt.toElement && typeof = element.contains !=3D 'undefined') {=0A= return !element.contains(evt.toElement);=0A= }=0A= else if (typeof evt.relatedTarget !=3D 'undefined' && evt.relatedTarget) = {=0A= return !contains(element, evt.relatedTarget);=0A= }=0A= }=0A= function contains (container, containee) {=0A= while (containee) {=0A= if (container =3D=3D containee) {=0A= return true;=0A= }=0A= containee =3D containee.parentNode;=0A= }=0A= return false;=0A= }=0A= // functions for showing/hiding layers using the "style.visibility" = method=0A= function toggleLayerVisibility(layername,showhide,focus) {=0A= var thislayer =3D new getObject(layername);=0A= if (showhide) {=0A= thislayer.style.visibility =3D showhide;=0A= }=0A= else if ((thislayer.style.visibility =3D=3D 'hidden') || = (thislayer.style.visibility =3D=3D 'hide')) {=0A= thislayer.style.visibility =3D 'visible';=0A= }=0A= else {=0A= thislayer.style.visibility =3D 'hidden'; }=0A= if (focus) {=0A= eval("document."+focus+".focus();");=0A= }=0A= }=0A= function makeLayerInvisible(layername,focus) {=0A= toggleLayerVisibility(layername,'hidden',focus);=0A= }=0A= function makeLayerVisible(layername,focus) {=0A= toggleLayerVisibility(layername,'visible',focus);=0A= }=0A= // functions for showing/hiding layers using the "style.display" method=0A= function toggleLayerDisplay(layername,showhide,focus) {=0A= var thislayer =3D new getObject(layername);=0A= if (thislayer.obj !=3D null) {=0A= if (showhide =3D=3D 'hide') {=0A= thislayer.style.display =3D 'none'; }=0A= else if (showhide =3D=3D 'show') {=0A= thislayer.style.display =3D ''; }=0A= else {=0A= var thislayer =3D new getObject(layername);=0A= if (thislayer.style.display =3D=3D 'none') {=0A= thislayer.style.display =3D '';=0A= }=0A= else {=0A= thislayer.style.display =3D 'none'; }=0A= }=0A= // if layer in view and we have a focus, set it=0A= if (focus) {=0A= if (thislayer.style.display =3D=3D '') {=0A= eval("document."+focus+".focus();");=0A= }=0A= }=0A= }=0A= }=0A= // functions for showing/hiding popup items on main menu=0A= function ShowLoginBox() {=0A= toggleLayerDisplay('loginboxbar',0,'quicklogin.username');=0A= }=0A= function ShowMyDekkerMenu() {=0A= toggleLayerDisplay('quickloginbox','hide');=0A= // checkLayerOnScreen('mydekker');=0A= toggleLayerDisplay('mydekker');=0A= return false;=0A= }=0A= // Functions for working out size of browser window, scroll postions and = repostioning layers on screen=0A= function getBrowserWindowScrollXY() {=0A= var scrOfX =3D 0, scrOfY =3D 0;=0A= if( typeof( window.pageYOffset ) =3D=3D 'number' ) {=0A= //Netscape compliant=0A= scrOfY =3D window.pageYOffset;=0A= scrOfX =3D window.pageXOffset;=0A= }=0A= else if( document.body && ( document.body.scrollLeft || = document.body.scrollTop ) ) {=0A= //DOM compliant=0A= scrOfY =3D document.body.scrollTop;=0A= scrOfX =3D document.body.scrollLeft;=0A= }=0A= else if( document.documentElement &&=0A= ( document.documentElement.scrollLeft || = document.documentElement.scrollTop ) ) {=0A= //IE6 standards compliant mode=0A= scrOfY =3D document.documentElement.scrollTop;=0A= scrOfX =3D document.documentElement.scrollLeft;=0A= }=0A= return [ scrOfX, scrOfY ];=0A= }=0A= function getBrowserWindowSizeXY() {=0A= var myWidth =3D 0, myHeight =3D 0;=0A= if( typeof( window.innerWidth ) =3D=3D 'number' ) {=0A= //Non-IE=0A= myWidth =3D window.innerWidth;=0A= myHeight =3D window.innerHeight;=0A= }=0A= else if( document.documentElement &&=0A= ( document.documentElement.clientWidth || = document.documentElement.clientHeight ) ) {=0A= //IE 6+ in 'standards compliant mode'=0A= myWidth =3D document.documentElement.clientWidth;=0A= myHeight =3D document.documentElement.clientHeight;=0A= }=0A= else if( document.body && ( document.body.clientWidth || = document.body.clientHeight ) ) {=0A= //IE 4 compatible=0A= myWidth =3D document.body.clientWidth;=0A= myHeight =3D document.body.clientHeight;=0A= }=0A= return [ myWidth, myHeight ];=0A= }=0A= function findCursorXYCoordinates(evt) {=0A= var x =3D 0, y =3D 0;=0A= if (evt.x) {=0A= x =3D evt.x;=0A= y =3D evt.y;=0A= }=0A= else if (evt.pageX) {=0A= x =3D evt.pageX;=0A= y =3D evt.pageY;=0A= }=0A= return [ x, y ];=0A= }=0A= function getLayerSizeXY(layername) {=0A= var height =3D 0, width =3D 0;=0A= if (document.getElementById) {=0A= height =3D document.getElementById(layername).offsetHeight;=0A= width =3D document.getElementById(layername).offsetWidth;=0A= }=0A= else if (document.all) {=0A= height =3D document.all[layername].clientHeight;=0A= width =3D document.all[layername].clientWidth;=0A= }=0A= else if (document.layers) {=0A= height =3D document.layers[layername].document.height;=0A= width =3D document.layers[layername].document.width;=0A= }=0A= return [width, height];=0A= }=0A= function checkLayerOnScreen(layername) {=0A= var thislayer =3D new getObject(layername);=0A= var layersizexy =3D getLayerSizeXY(layername);=0A= var browsersizexy =3D getBrowserWindowSizeXY();=0A= var scrollxy =3D getBrowserWindowScrollXY();=0A= var layerx =3D parseInt(thislayer.style.left);=0A= var layery =3D parseInt(thislayer.style.top);=0A= // check the x pos=0A= // Is it off the right?=0A= var layerright =3D layerx + layersizexy[0];=0A= if (layerright > browsersizexy[0]) {=0A= var newx =3D browsersizexy[0] - layersizexy[0] - 5;=0A= // take in to account the scroll position=0A= // note, Netscape takes scroll pos in to account in the cursor pos so no = need to do it here for Netscape=0A= if (navigator.appName !=3D "Netscape") {=0A= newx +=3D scrollxy[0];=0A= }=0A= // set the x coordinate=0A= thislayer.style.left =3D newx=0A= }=0A= // Is it off the left?=0A= if (layerx < scrollxy[0]) {=0A= var newx =3D scrollxy[0] + 5;=0A= // set the x coordinate=0A= thislayer.style.left =3D newx=0A= }=0A= // check the y pos=0A= // Is it off the bottom?=0A= var layerbottom =3D layery + layersizexy[1];=0A= if (layerbottom > browsersizexy[1]) {=0A= var newy =3D browsersizexy[1] - layersizexy[1] - 5;=0A= // take in to account the scroll position=0A= // note, Netscape takes scroll pos in to account in the cursor pos so no = need to do it here for Netscape=0A= if (navigator.appName !=3D "Netscape") {=0A= newy +=3D scrollxy[1];=0A= }=0A= // set the y coordinate=0A= thislayer.style.top =3D newy=0A= }=0A= // Is it off the top?=0A= if (layery < scrollxy[1]) {=0A= var newy =3D scrollxy[1] + 5;=0A= // set the y coordinate=0A= thislayer.style.top =3D newy=0A= }=0A= }=0A= function moveLayerToCursor(layername,evt) {=0A= var cursorxy =3D findCursorXYCoordinates(evt);=0A= var layersizexy =3D getLayerSizeXY(layername);=0A= var browsersizexy =3D getBrowserWindowSizeXY();=0A= var thislayer =3D new getObject(layername);=0A= var scrollxy =3D getBrowserWindowScrollXY();=0A= var cursoroffset =3D 5; // how many pixels way from cursor to postion = layer=0A= // work out new x coordinate=0A= var newx =3D cursorxy[0] + cursoroffset;=0A= // check not off the right of page=0A= var layerright =3D newx + layersizexy[0];=0A= if (layerright > browsersizexy[0]) {=0A= newx =3D newx - layersizexy[0] - (2 * cursoroffset);=0A= // take in to account the scroll position=0A= // note, Netscape takes scroll pos in to account in the cursor pos so no = need to do it here for Netscape=0A= if (navigator.appName !=3D "Netscape") {=0A= newx +=3D scrollxy[0];=0A= }=0A= }=0A= // set the x coordinate=0A= thislayer.style.left =3D newx=0A= // work out y coordinate=0A= var newy =3D cursorxy[1] - layersizexy[1] - cursoroffset;=0A= // take in to account the scroll position=0A= // note, Netscape takes scroll pos in to account in the cursor pos so no = need to do it here for Netscape=0A= if (navigator.appName !=3D "Netscape") {=0A= newy +=3D scrollxy[1];=0A= }=0A= // check not off the top of the screen=0A= if (newy < scrollxy[1]) {=0A= newy =3D cursorxy[1] + cursoroffset;=0A= if (navigator.appName !=3D "Netscape") {=0A= newy +=3D scrollxy[1];=0A= }=0A= }=0A= // set the y coordinate=0A= thislayer.style.top =3D newy;=0A= }=0A= function SubmitIfEnterPressed(e,form,thisvalue) { if (thisvalue !=3D "") = {=0A= if (!e) {=0A= var e =3D window.event;=0A= }=0A= var key;=0A= if (e.keyCode) {=0A= key =3D e.keyCode;=0A= } else if (e.which) {=0A= key =3D e.which;=0A= }=0A= if (key =3D=3D 13) {=0A= eval('document.'+form+'.submit();');=0A= }=0A= }=0A= }=0A= function SelectAll(formname,groupname,allname) {=0A= // see what setting now is=0A= var ischecked =3D eval('document.'+formname+'.'+allname+'.checked');=0A= newstatus =3D "";=0A= if (ischecked =3D=3D true) {=0A= newstatus =3D "true";=0A= }=0A= var numboxes =3D eval('document.'+formname+'.'+groupname+'.length');=0A= if (numboxes =3D=3D undefined) {=0A= eval('document.'+formname+'.'+groupname+'.checked =3D newstatus');=0A= }=0A= else {=0A= for (i=3D0; i");=0A= }=0A= else {=0A= thislayer.style.display =3D 'none'; divPopulate('link'+layername,"3D\"Expand\"");=0A= }=0A= }=0A= function toggleBranchDisplayABES(layername,showhide,focus) {=0A= var thislayer =3D new getObject('bit'+layername);=0A= if ( ((thislayer.style.display =3D=3D 'none') || (showhide =3D=3D = 'show')) && (showhide !=3D 'hide') ){=0A= thislayer.style.display =3D '';=0A= divPopulate('link'+layername,"3D\"Contract\"");=0A= }=0A= else {=0A= thislayer.style.display =3D 'none'; divPopulate('link'+layername,"3D\"Expand\"");=0A= }=0A= }=0A= function populateElement(selector, defvalue) {=0A= if($(selector).attr('value') =3D=3D null) {=0A= $(selector).attr('value', defvalue);=0A= }=0A= $(selector).focus(function() {=0A= if($(selector).attr('value') =3D=3D defvalue) {=0A= $(selector).attr('value','' );=0A= }=0A= });=0A= $(selector).blur(function() {=0A= if($(selector).attr('value') =3D=3D null || $(selector).attr('value') = =3D=3D "") {=0A= $(selector).attr('value', defvalue);=0A= }=0A= });=0A= }=0A= ------=_NextPart_000_0000_01C8719C.F19834A0--