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Glioma migration: clues from the biology of
neural progenitor cells and embryonic CNS cell migration
Dirks PB
Division of Neurosurgery, Hospital for Sick Children, University
of Toronto, Ontario, Canada. peter.dirks@sickkids.on.ca
Neural stem cells have recently come to the forefront in neurobiology because of
the possibilities for CNS repair by transplantation.
Further understanding of the biology of these cells is critical for making their
use in CNS repair possible.
It is likely that these discoveries will also have spin-offs for neuro-oncology
as primary brain tumors may arise from a CNS progenitor cell.
An understanding of the normal migratory ability of these cells is also likely
to have a very important impact on the knowledge of brain tumor invasion.
PMID: 11716071 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11716071&dopt=Abstract
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