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How
often are nonenhancing supratentorial gliomas malignant?
A population study
Scott JN, Brasher PM, Sevick RJ, Rewcastle NB, Forsyth PA
Department of Diagnostic Imaging, University of Calgary, Alberta,
Canada.
The presence of contrast enhancement in a brain tumor is often regarded as a
sign of malignancy.
The authors identified 314 patients with malignant and low-grade supratentorial
glial neoplasms in an unselected population, 58 of which lacked contrast
enhancement on preoperative neuroimaging.
Nonenhancing gliomas were malignant in approximately one third of cases,
especially in older patients.
Histologic confirmation of the diagnosis is therefore important in all patients
suspected of harboring a primary glial neoplasm.
PMID: 12297589 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12297589&dopt=Abstract
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