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Impairments in premorbid knowledge recall in
patients with hemispheric and intraventricular brain damage
Buklina SB
Academician N. N. Burdenko Science Research Institute of
Neurosurgery, Russian Academy of Medical Sciences, Moscow.
A total of 104 patients with hemispheric arteriovenous malformations (AVM; in
the frontal, parietal, and temporal lobes), along with 21 patients with
craniopharyngiomas and 21 patients with aresorptive hydrocephalus, were
studied.
Impairments of the recall of knowledge acquired before disease onset were found
in 12 patients with hemispheric AVM.
All had suffered severe intraventricular hemorrhage.
Similar memory defects were noted in three patients with craniopharyngiomas and
12 with hydrocephalus.
These patients had lesions of the mediobasal (periventricular) parts of the
brain (frontal and parietal lobes), predominantly of the right hemisphere, as
well as the diencephalic regions.
The syndrome of selective retrograde amnesia in lesions of these structures was
characterized by impairment of the recall of dates and, less frequently, details
of event content and autobiography.
It is emphasized that processes of recall of the sequence and selectivity of
traces during actualization of "old" knowledge played the greater role
in the mechanism of development of these impairments.
The possible roles of the right and left hemispheres, as well as the
diencephalic area, in the information encoding and decoding are discussed.
PMID: 14969434 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14969434
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