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[A
case of subependymal giant cell astrocytoma not associated with tuberous
sclerosis]
[Article in Japanese]
Watanabe Y, Oki S, Migita K, Isobe N, Okazaki T, Nabika S
Department of Neurosurgery, Hiroshima City Asa Hospital, 2-1-1
Kabe-minami, Kita-ku, Asa, Hiroshima-city, Hiroshima 731-0293, Japan.
The authors present a case of a subependymal giant cell astrocytoma (SGCA) not
associated with tuberous sclerosis.
On admission, a six-year-old boy had obstructive hydrocephalus caused by a huge
intraventricular tumor.
Preoperative T1-weighted MR images with gadolinium showed heterogeneous
enhancement of the lesion.
The tumor was totally removed through a right transcortical approach with
frontal craniotomy.
Immunohistochemical staining for glial fibrillary acidic protein (GFAP) showed a
positive reaction in some of the large tumor cells and the labeling index of
MIB-1 was < 1.0%.
Histological examinations revealed SGCA.
He has no other evidence of tuberous sclerosis at present, but the patient in
this case is an infant, so there is a possibility of his being diagnosed as
tuberous sclerosis in the future.
Therefore, systemic regular follow-up is recommended, even when his condition is
asymptomatic.
PMID: 12755028 [PubMed - indexed for MEDLINE]
Source:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12755028&dopt=Abstract
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