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Emerging
tumor entities and variants of CNS neoplasms
Cenacchi G, Giangaspero F
Department of Radiology and
Pathology, University of Bologna, Bologna, Italy.
Since the appearance in 2000 of the World Health Organization (WHO)
classification for central nervous system (CNS) neoplasms, numerous descriptions
of new entities or variants have appeared in the literature.
In the group of
neuronal and mixed glioneuronal neoplasms are lesions with distinctive
morphological features that are still not included in a precise classification,
including extraventricular neurocytoma, papillary glioneuronal tumor,
rosette-forming glioneuronal of the fourth ventricle, glioneuronal with
neuropil-like rosette, and DNT-like tumor of the septum pellucidum.
The
glioneuronal tumor with neuropil-like rosette and oligodendroglioma with
neurocytic differentiation represent morphological variants of genetically
proven diffuse gliomas.
The lipoastrocytoma and the pilomixoid astrocytoma
enlarge the group of astrocytic lesions.
Rare, low-grade gliomas of the spinal
cord with extensive leptomeningeal dissemination associated with unusual
neuroimaging are described.
The chordoid glioma of the third ventricle and the
papillary tumor of the pineal region seem to be correlated by a common
histogenesis from the specialized ependyma of the subcommissural organ.
An
embryonal tumor with neuropil and true rosettes combining features of
neuroblastoma and ependymoblastoma is discussed.
These new, recently described
lesions indicate that the complex morphologic spectrum of CNS tumors is far from
being completely delineated.
PMID: 15055442 [PubMed - indexed for MEDLINE]
Source:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15055442
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