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Large cell neuroendocrine carcinoma of the
uterine corpus metastatic to brain and lung: case report and review of the
literature
Erhan Y, Dikmen Y, Yucebilgin MS, Zekioglu O, Mgoyi L, Terek MC
Department of Pathology, Ege University, Faculty of Medicine,
Bornova, Izmir, Turkey.
Neuroendocrine carcinoma of the uterine corpus is a rare aggressive tumor with a
similar unfavorable outcome to that of the cervix.
The large cell type is considerably rarer than the small cell neuroendocrine
carcinoma of the uterine corpus.
We report a case of a 52-year-old woman who presented with a large cell
neuroendocrine tumor of the uterine corpus with very aggressive clinical
behavior, cerebral and pulmonary metastases six and four months after initial
diagnosis and adjuvant radiotherapy, respectively.
Despite successful surgical extirpation of the cerebral metastatic lesion she
did not respond to chemotherapy and died four months after disease recurrence.
PMID: 15053077 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15053077
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