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Treatment
of low-grade oligodendroglial tumors without radiotherapy
Yoshinori
Higuchi, MD, Yasuo Iwadate, MD and Akira Yamaura, MD
Department
of Neurological Surgery, Chiba University Graduate School of Medicine,
Chiba, Japan. Address correspondence and reprint requests to Dr. Yasuo
Iwadate, Department of Neurological Surgery, Chiba University Graduate
School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba
260-8670, Japan; e-mail: iwadatey@faculty.chiba-u.jp.
Received
March 22, 2004. Accepted in final form August 2, 2004.
The
authors prospectively treated 18 consecutive patients with low-grade
oligodendroglial tumors without postoperative radiotherapy.
The
treatment strategy was as follows: follow-up after total resection
and chemotherapy after subtotal resection or biopsy.
All
patients were alive and 17 patients (94%) were progression-free after
a median follow-up of 4.7 years.
The
results suggested that radiotherapy could be postponed
until clinical progression in the treatment of low-grade
oligodendroglial tumors.
©
2004 American
Academy of Neurology
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