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Use
of fractional anisotropy value by diffusion tensor MRI for
preoperative diagnosis of astrocytic tumors: case report
Toshinari Misaki, Takaaki Beppu,
Takashi Inoue, Kuniaki Ogasawara, Akira Ogawa, Hiroyuki Kabasawa
Department of Neurosurgery,
Iwate Medical University, Uchimaru 19-1, Morioka, 020-8505, Japan
[T.M., T.B., T.I., K.O., A.O.]. GE Yokogawa Medical Systems, Tokyo,
Japan [H.K.].
The fractional anisotropy (FA)
value calculated by diffusion tensor MRI can indicate the degree of
directionality of water diffusion in astrocytic tumors.
Here, we report a case of anaplastic astrocytoma in which FA proved
invaluable for the preoperative differential diagnosis.
A 60-year-old man complained of headache, and underwent routine
neuroimaging and DTI.
The routine images suggested a low-grade glioma in the left temporal
lobe, based on lack of enhancement on MRI with contrast medium and
lack of tumor staining on angiograms, whereas FA value was very
high.
Based on these findings, a preoperative diagnosis of high-grade glioma
was suspected.
The surgical specimen exhibited the histological features of
anaplastic astrocytoma with a high density of spindle shaped cells and
low vascularity.
In this report, we discuss the relationship between FA and other
characteristics of the present tumor, and discuss the utility of FA
measurement in astrocytic tumors.
Keywords: diagnosis, diffusion tensor
MRI, fractional anisotropy, glioma, histological structure
Copyright © 2004 Kluwer Academic Publishers.
All rights reserved
Source: http://ipsapp009.kluweronline.com/IPS/content/ext/x/J/5042/I/126/A/3/abstract.htm
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