Treatment > Surgical Neuro-Oncology


J Neurooncol, 69(1):291-318, Aug-Sept 2004. (Review Article)


Abstract

Spinal Cord and Intradural-Extraparenchymal Spinal Tumors: Current Best Care Practices and Strategies

Andrew T. Parsa, Janet Lee, Ian F. Parney, Philip Weinstein, Paul C. McCormick, Christopher Ames

University of California, 505 Parnassus Avenue, M-779, UCSF-Department of Neurological Surgery, San Francisco, California, 94143, USA; Tel.: +1-415-353-2629; E-mail: parsaa@neurosurg.ucsf.edu [A.T.P.]. Department of Neurological Surgery, University of California [J.L., I.F.P., P.W., C.A.]. Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, San Francisco, CA, USA [P.C.M.].

The management of patients with intradural spinal tumors differs in many respects from approaches taken for patients with intracranial tumors. 
Intramedullary lesions are often completely surrounded by normal spinal cord, displacing vital functional tracts eccentrically. 
Extramedullary lesions can drastically compress the spinal cord and nerve roots, reducing normal tissue to a ribbon-like consistency. 
The small amount of normal tissue relative to tumor has implications for surgery and postoperative adjuvant therapy. 
In addition, operative intervention must take spinal stability into consideration. 
In this report, we describe the current best care practices and strategies for patients with a diagnosis of spinal astrocytoma, ependymoma, hemangioblastoma, schwannoma, and meningioma. 
Treatment of patients with intradural tumors of the spinal cord and adjoining structures has changed over the past 20 years. 
Advances in many disciplines including neuroradiology, neurosurgery, neurooncology, and neuropathology have contributed to expediting diagnosis and improving outcomes.

Keywords: ependymoma, hemangioblastoma, meningioma, schwannoma, spinal astrocytoma

Copyright © 2004 Kluwer Academic Publishers. All rights reserved

Source: http://ipsapp007.kluweronline.com/IPS/content/ext/x/J/5042/I/124/A/22/abstract.htm


 

HOME | Detection | Diagnosis | Epidemiology | Etiology & Pathogenesis | Integrative Medicine | Overall Mngt & Case Reports | Prevention | Prognosis | Psychosocial Aspects | Treatment 
About BrainLife
|
Children's Corner | E-mail Alerts | Journals | Newsletter | Patients & Caregivers | Search | Stem Cells | WHO Classification | SITEMAP