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Prognostic value of the MIB-1 labeling index for
central neurocytomas
Rades D, Schild SE, Fehlauer F
Department of Radiation Oncology, University Hospital
Hamburg-Eppendorf, Hamburg, Germany. Rades.Dirk@gmx.net
Although central neurocytomas are generally described as benign CNS lesions,
malignant behavior including craniospinal dissemination and tumor-related death
may occur. This meta-analysis was performed to investigate the prognostic value
of the MIB-1 labeling index. Data were obtained not from the literature alone
but also from contact with the authors. The data suggested an MIB-1 index score
of >3% to be associated with a worse prognosis for local control (p <
0.0001) and survival (p = 0.0004).
PMID: 15037708 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15037708
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