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Pediatric
Surgical Neuro-Oncology: Current Best Care Practices and Strategies
James T. Rutka, John S. Kuo
The
Arthur and Sonia Labatt Brain Tumour Research Centre and Division of
Neurosurgery, Suite 1502, The Hospital for Sick Children, 555
University Avenue, Toronto, Ontario, Canada M5G 1X8, Tel.:
1-416-813-6425; Fax: 1-416-813-4875; E-mail: james.rutka@sickkids.ca
[J.T.R.]. The Arthur and Sonia Labatt Brain Tumour Research
Centre and Division of Neurosurgery, The Hospital for Sick Children,
University of Toronto, Toronto, Ontario, Canada; Department of
Neurological Surgery, Keck School of Medicine, University of Southern
California, Los Angeles, CA, USA [J.S.K.].
Significant
advances have been made in the diagnosis and treatment of childhood
brain tumors.
Gross total surgical resection combined with appropriate adjuvant
therapies can achieve a high rate of disease control for low grade
gliomas, ependymomas and medulloblastomas.
High grade gliomas, tumors involving the optic apparatus or
diencepahalic structures, diffuse brainstem lesions, and recurrent or
metastatic disease still pose considerable therapeutic
challenges.
We review the current treatment strategies of the three most common
types of pediatric brain tumors: gliomas, medulloblastomas and
ependymomas, and discuss current and future diagnostic and therapeutic
modalities.
Keywords: ependymoma,
glioma, medulloblastoma, pediatric brain tumors, pilocytic astrocytoma
Copyright
©
2004 Kluwer Academic Publishers.
All rights reserved
Source: http://ipsapp007.kluweronline.com/IPS/content/ext/x/J/5042/I/124/A/10/abstract.htm
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