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Carcinomatous
Meningitis as the Presenting Manifestation of Gallbladder Carcinoma: Case Report
and Review of the Literature
Yue Shen, Deborah T. Blumenthal, Kathleen Digre,
Melissa H. Cessna, Evelyn V. Gopez
Department
of Neurology, University of Utah Hospital, 50 North Medical Room, Rm 3R210, UT
84132, Salt Lake City, USA; Tel.: +1-801-585-0932; Fax: +1-801-581-4192; E-mail:
jason.shen@usa.net
[Y.S.]. Department of Neurology, University of Utah Hospital,
Salt Lake City, UT, USA; Department of Neurosurgery, University of Utah
Hospital, Salt Lake City, UT, USA; Division of Oncology, University of Utah
Hospital, Salt Lake City, UT, USA; Department of Medicine, University of Utah
Hospital, Salt Lake City, UT, USA [D.T.B.]. Department of Neurology, University of Utah Hospital,
Salt Lake City, UT, USA; Department of Ophthalmology, University of Utah
Hospital, Salt Lake City, UT, USA [K.D.].
Department of Pathology, University of Utah Hospital,
Salt Lake City, UT, USA [M.H.C.,
E.V.G.].
The
primary tumors that typically cause carcinomatous meningitis include lung
cancer, breast cancer, leukemia, lymphoma and melanoma.
A variety of neurological signs and symptoms can be seen depending on the extent
and location of the meningeal metastasis.
Once the diagnosis of carcinomatous meningitis is confirmed, the search for the
primary tumor can be a challenge and at times may require extensive radiographic
or even surgical evaluation to obtain specimen for pathological
confirmation.
Here we report a patient who presented with bilateral cranial nerve VIII and
cerebellar symptoms, and was diagnosed with carcinomatous meningitis.
Only after an exploratory laporatomy did it become clear that the initial
symptoms were related to a metastatic gallbladder carcinoma.
Keywords: carcinomatous
meningitis, gallbladder carcinoma, leptomeningeal metastasis, meningeal
carcinomatosis and cranial neuropathy
Copyright
©
2004 Kluwer Academic Publishers.
All rights reserved
Source: http://ipsapp009.kluweronline.com/IPS/content/ext/x/J/5042/I/123/A/7/abstract.htm
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