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Recurrent intracranial hemangiopericytoma with
extracranial and unusual multiple metastases: case report and review of the
literature
Spatola C, Privitera G
Servizio di Radioterapia, Policlinico Universitario di Catania,
Italy. cor_spatola@hotmail.com
Hemangiopericytoma is a rare tumor with uncommon location in the central nervous
system.
It has only recently been included (WHO classification 1993) in a specific group
of CNS tumors and subsequently (WHO classification 1997 and 2000) as a group by
itself, while before it was confused with meningeal tumors.
We report on a case of a 48-year-old woman affected by this tumor.
The neoplasm was located in the posterior fossa.
The patient underwent primary surgery in 1990, not followed by any adjuvant
therapy because of the histopathological diagnosis of meningioma.
After being free from disease for eight years she developed a local recurrence
in 1998.
Subtotal excision of the tumor, which was finally identified as a
hemangiopericytoma, was carried out, followed by adjuvant radiotherapy (64
Gy).
After six months multiple metastases were found in the liver and right
kidney.
A radical metastasectomy was performed, followed by systemic chemotherapy.
One year later (2001) the tumor recurred again intracranially and a metastases
was detected in the right breast, so the patient again underwent cranial
irradiation (40 Gy) and second-line chemotherapy.
She died in September 2002, 12 years after the diagnosis.
We may conclude that, despite the tumor's natural tendency to recur several
times and the ability of intracranial hemangiopericytoma to spread outside the
CNS, it is possible to ensure a long survival time.
PMID: 15237597 [PubMed - indexed for MEDLINE]
Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15237597
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