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Treatment > Radiosurgery


J Neurooncol, 69(1):125-137, Aug-Sept 2004. (Review Article)


Abstract

Stereotactic Radiosurgery for Patients with Solid Brain Metastases: Current Status

Ronald E. Warnick, Borimir J. Darakchiev, John C. Breneman

c/o Editorial office, The Neuroscience Institute, Department of Neurosurgery, University of Cincinnati College of Medicine 231 Albert Sabin Way, ML 0515, Cincinnati, OH 45267-0515, USA; Tel.: +1-513-558-3563; Fax: +1-513-558-7702; E-mail: editor@mayfieldclinic.com [R.E.W.]. Department of Neurosurgery [B.J.D.]; Department of Radiology Radiation Oncology Division [J.C.B.], Neuroscience Institute, University of Cincinnati College of Medicine, Ohio, USA.

The goal of this article is to provide a contemporary update on the use of stereotactic radiosurgery (SRS) for the treatment of intracranial metastatic disease. 
We discuss the rationale for employing SRS in brain metastases and describe the critical factors that predict outcome. 
We highlight the main clinical indications for SRS including treatment of recurrent brain metastases after previous whole brain radiation therapy (WBRT), as a boost after WBRT, and as sole therapy for newly diagnosed tumors. 
For each clinical scenario, we offer a treatment algorithm based on our clinical experience. 
The article also addresses the most common complications associated with SRS and their treatment.

Keywords: brain metastases, complications, stereotactic radiosurgery, surgery, whole brain radiotherapy

Copyright © 2004 Kluwer Academic Publishers. All rights reserved

Source: http://ipsapp007.kluweronline.com/IPS/content/ext/x/J/5042/I/124/A/9/abstract.htm


 

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