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Stereotactic
Radiosurgery for Patients with Solid Brain Metastases: Current Status
Ronald E. Warnick, Borimir J. Darakchiev, John C.
Breneman
c/o
Editorial office, The Neuroscience Institute, Department of Neurosurgery,
University of Cincinnati College of Medicine 231 Albert Sabin Way, ML 0515,
Cincinnati, OH 45267-0515, USA; Tel.: +1-513-558-3563; Fax: +1-513-558-7702;
E-mail: editor@mayfieldclinic.com
[R.E.W.]. Department of Neurosurgery [B.J.D.]; Department of
Radiology – Radiation Oncology Division [J.C.B.], Neuroscience
Institute, University of Cincinnati College of Medicine, Ohio, USA.
The goal
of this article is to provide a contemporary update on the use of stereotactic
radiosurgery (SRS) for the treatment of intracranial metastatic disease.
We discuss the rationale for employing SRS in brain metastases and describe the
critical factors that predict outcome.
We highlight the main clinical indications for SRS including treatment of
recurrent brain metastases after previous whole brain radiation therapy (WBRT),
as a boost after WBRT, and as sole therapy for newly diagnosed tumors.
For each clinical scenario, we offer a treatment algorithm based on our clinical
experience.
The article also addresses the most common complications associated with SRS and
their treatment.
Keywords: brain
metastases, complications, stereotactic radiosurgery, surgery, whole brain
radiotherapy
Copyright
©
2004 Kluwer Academic Publishers.
All rights reserved
Source: http://ipsapp007.kluweronline.com/IPS/content/ext/x/J/5042/I/124/A/9/abstract.htm
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