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Cerebellar liponeurocytoma/lipidized medulloblastoma. Case report and
review of the literature Fügen Vardar Aker,
Selvinaz Özkara, Pinar Eren, Önder Peker,
Serdar Armağan
and Tayfun Hakan
Department of Pathology, Haydarpasa
Numune Education and Research Hospital, Turkey [F.V.A., S.Ö.,
Ö.P.]. Department of Molecular Pathology,
Haydarpasa Numune Teaching and Research Hospital, Marmara University
Medical Biology and Genetic Department, Turkey [P.E.]. Department of Neurosurgery, Haydarpasa
Numune Teaching and Research Hospital, Istanbul, Turkey [S.A., T.H.]. 81140, Karayollari Site Sok, Barbaros
Mah, Soyak Gokyuzu Konutlari, A-Blok No. 29,
Altunizade-Uskudar-Istanbul, Turkey [F.V.A.].
Correspondence to: Fügen Vardar Aker,
Email: fugenaker@yahoo.com, Phone: +90-216-651-31-72, Fax: +90-216-449-48-42.
Cerebellar liponeurocytoma that has been recently identified as a
distinct entity by the World Health Organization is characterized by
areas of lipomatous differentiation and apparently by a favorable
prognosis.
In this paper, we described a case of 49-year-old female
showing progressive clinical course inspite of a low labeling/mitotic
index.
We also review the relevant literature.
Although, basically all
reported cases share a similar histological pattern, i.e. focal
accumulations of adiposities in an otherwise typical small cell tumor
like central neurocytoma, some clinical properties such as (age,
proliferative potential, therapy and survival) are not uniform.
The
exact biological behavior of this special variant tumor is
established.
Yet, this needs further confirmation on a large number of
cases with longer follow-up periods.
Keywords adipose
tissue - cerebellar neoplasm - lipidization - liponeurocytoma - medulloblastoma
© Springer 2005
Source: http://springerlink.metapress.com/openurl.asp?genre=article&eissn=1573-7373&volume=71&issue=1&spage=53
DOI: http://dx.doi.org/10.1007/s11060-004-9172-4
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