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Journal of the National Cancer Institute, Vol. 98, No. 14, 945-946, July 19, 2006; DOI: 10.1093/jnci/djj293


Editorial

Extract

(Nutritional) Chemoprevention of Cancer: What's Up?

John A. Baron

Correspondence to: John A. Baron, MD, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Evergreen Center, 46 Centerra Pkwy., Ste. 300, Lebanon, NH 03766 (e-mail: john.a.baron@dartmouth.edu ).


The first 10% of the full text of this article appears below.

Some of the initial motivation for cancer chemoprevention was derived from observations regarding the effects of nutrients on carcinogenesis, and so it is fitting that the Journal now publishes a progress report of sorts for nutritional interventions.  
Davies et al. (1) have assumed the difficult task of summarizing the effects of all nutritional interventions across all the studied populations and endpoints. 
With the heterogeneity inherent in each of these, there is clearly a risk of mixing apples and oranges into an uninterpretable stew. 
However, even if the summary estimates may be . . . [Full Text of this Article]


© The Author 2006. Published by Oxford University Press
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Refers to

Anna A. Davies, George Davey Smith, Roger Harbord, Geertruida E. Bekkering, Jonathan A. C. Sterne, Rebecca Beynon, Steven Thomas
Nutritional Interventions and Outcome in Patients With Cancer or Preinvasive Lesions: Systematic Review
Journal of the National Cancer Institute, Vol. 98, No. 14, 961-973, July 19, 2006
; DOI: 10.1093/jnci/djj263

Wei-cheng You, Linda M. Brown, Lian Zhang, Ji-you Li, Mao-lin Jin, Yun-shen Chang, Jun-ling Ma, Kai-feng Pan, Wei-dong Liu, Yuanreng Hu, Susan Crystal-Mansour, David Pee, William J. Blot, Joseph F. Fraumeni, Jr., Guang-wei Xu, Mitchell H. Gail
Randomized Double-Blind Factorial Trial of Three Treatments To Reduce the Prevalence of Precancerous Gastric Lesions
Journal of the National Cancer Institute, Vol. 98, No. 14, 974-983, July 19, 2006; DOI: 10.1093/jnci/djj264



 

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