Etiology and Pathogenesis > Tumor Biology


Molecular Cancer 2006, 5:60; doi:10.1186/1476-4598-5-60; Published: 8 November 2006.


Abstract

Epigenetic aberrations and cancer

Miryam Ducasse1* and Mark A Brown2*

1Institute for Biomedical Research Georg-Speyer-Haus, 60596 Frankfurt, Germany. 2Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station A5000, Austin TX 78712, USA -- *Corresponding authors: Email: Miryam Ducasse* - ducasse@em.uni-frankfurt.de; Mark A Brown* - sambrown750@gmail.com -- Received: 31 October 2006; Accepted: 8 November 2006; Published: 8 November 2006.


The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms. 
Here, we review recent findings regarding chromatin modifications and their relevance to cancer.

© 2006 Ducasse and Brown; licensee BioMed Central Ltd.
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