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Mobile phone use and risk of glioma in
adults: case-control study
Sarah J Hepworth1,
Minouk J Schoemaker2, Kenneth
R Muir3, Anthony J Swerdlow2,
Martie J A van Tongeren4, Patricia
A McKinney1*
1Centre for Epidemiology
and Biostatistics, Leeds Institute of Genetics, Health, and
Therapeutics (LIGHT), Leeds LS2 9LN. 2Institute of Cancer
Research, Section of Epidemiology, Sutton, Surrey SM2 5NG. 3Division
of Epidemiology and Public Health, School of Community Health
Sciences, Queen's Medical Centre, Nottingham NG7 2UH. 4Centre
for Occupational and Environmental Health, Division of Epidemiology
and Health Sciences, University of Manchester, Manchester M13 9PL. *Correspondence
to: p.a.mckinney@leeds.ac.uk. Accepted 14
November 2005.
Objective. To investigate
the risk of glioma in adults in relation to mobile phone
use.
Design. Population based
case-control study with collection of personal interview
data.
Setting. Five areas of
the United Kingdom.
Participants. 966 people
aged 18 to 69 years diagnosed with a glioma from 1 December
2000 to 29 February 2004 and 1716 controls randomly
selected from general practitioner lists.
Main outcome measures.
Odds ratios for risk of glioma in relation to mobile phone
use.
Results. The overall odds
ratio for regular phone use was 0.94 (95% confidence
interval 0.78 to 1.13).
There was no relation for risk of glioma and time since
first use, lifetime years of use, and cumulative number of
calls and hours of use.
A significant excess risk for reported phone use
ipsilateral to the tumour (1.24, 1.02 to 1.52) was paralleled
by a significant reduction in risk (0.75, 0.61 to 0.93) for
contralateral use.
Conclusions. Use of a
mobile phone, either in the short or medium term, is not
associated with an increased risk of glioma.
This is consistent with most but not all published
studies.
The complementary positive and negative risks associated
with ipsilateral and contralateral use of the phone in
relation to the side of the tumour might be due to recall
bias.
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