|
|
Small-molecule activation of
procaspase-3 to caspase-3 as a personalized anticancer strategy Karson
S Putt1, Grace W Chen2,
Jennifer M Pearson2, Joseph S
Sandhorst2, Martin S Hoagland3,
Jung-Taek Kwon4, Soon-Kyung
Hwang4, Hua Jin4,
Mona I Churchwell5, Myung-Haing
Cho4, Daniel R Doerge5,
William G Helferich3 and Paul
J Hergenrother1,2
1Department
of Biochemistry, University of Illinois, Urbana, Illinois 61801, USA.2Department
of Chemistry, University of Illinois, Urbana, Illinois 61801, USA.3Department
of Food Science and Human Nutrition, University of Illinois, Urbana,
Illinois 61801, USA.4Laboratory of
Toxicology, College of Veterinary Medicine and Nano Systems
Institute-National Core Research Center (NSI-NCRC), Seoul National
University, Seoul 151-742, South Korea.5US
Food and Drug Administration, National Center for Toxicological
Research, Jefferson, Arkansas 72029, USA. -- Correspondence to: Paul J
Hergenrother1,2 Email: hergenro@uiuc.edu.
|