Archives of Pathology and Laboratory Medicine = 132:77-80, 2008

From: Subject: Archives of Pathology and Laboratory Medicine 132:77-80, 2008 Date: Wed, 6 Feb 2008 16:02:14 +0100 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0000_01C868D9.A4078F90" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198 This is a multi-part message in MIME format. ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable Content-Location: http://arpa.allenpress.com/arpaonline/?request=get-abstract&issn=1543-2165&volume=132&page=77 Archives of Pathology and Laboratory Medicine = 132:77-80, 2008


<= IMG=20 height=3D30 alt=3DSearch=20 src=3D"http://arpa.allenpress.com/images/navbar3_02_01.gif" = width=3D199=20 border=3D0>

[Full-text=20 Article] [PDF=20 Version]
[PubMed=20 Citation] [Related=20 Articles in PubMed]

Archives of Pathology and Laboratory Medicine = 132:77=9680,=20 2008
=A9=20 Copyright by College of American Pathologists 2008=20

Archives of Pathology and Laboratory = Medicine:=20 Vol. 132, No. 1, pp. 77=9680.

Pediatric Pituitary Adenomas

Christopher Webb, MD; Richard A. Prayson, MD

From the Department of Anatomic Pathology, Cleveland Clinic=20 Foundation, Cleveland, = Ohio

Accepted August 8, 2007

Context.=97Pituitary adenomas are = relatively rare=20 occurrences in the pediatric population, and there are few studies=20 documenting the profile of these tumors in this age group.
Objective.=97To study the clinical and = pathologic=20 features of pediatric pituitary adenomas in conjunction with a = review of the=20 available literature.

Design.=97A retrospective = clinicopathologic review of=20 20 pediatric patients (younger than 20 years of age) with pituitary = adenomas=20 resected during a 24.5-year period (1981=962005).

Results.=97A total of 20 patients, = including 12=20 females and 8 males, comprise the study group. Mean age at onset of = symptoms=20 was 14.0 years (range, 5=9618 years). Four patients had onset of = symptoms=20 before the age of 12 years. The majority of patients presented with=20 headaches (n =3D 12), visual disturbances (n =3D 12) or, in females, = menstrual=20 dysfunction (n =3D 9/12). Tumor size based on radiographic data was = known for=20 19 tumors; 12 adenomas were greater than 1 cm in greatest dimension, = and 7=20 were less than 1 cm. On follow-up, 2 patients with total gross tumor = resections had recurrent adenomas; time to recurrence was 5 months = and 17=20 months, respectively. Nine adenomas stained solely for prolactin, 5 = for=20 adrenocorticotropic hormone, and 3 for growth hormone. Two stained = for=20 growth hormone and prolactin. One did not stain with hormone = antibodies.

Conclusions.=97Most pediatric pituitary = adenomas=20 present after the onset of puberty and present with frequent = headaches,=20 changes in visual acuity and, in females, menstrual dysfunction. = Most=20 (19/20) were secretory, with prolactinomas being the most common=20 type.

------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/images/navbar3_01_01.gif R0lGODlhxwAeAOYAAP////H1+ODp79Pg6dDd58TV4cDS37DG16O90KC7z5Cvxo6uxYOmwH+jvnqg u3ObuHCYtm2WtWaRsWSQsGKOr12LrFeGqVKDp02ApEp9o0N4n0B1nTpymzdvmjZumDNmmSxokzNm mShkkihjjyVjkCFgjiBejB9bhxlaihhYhhhWhBBThBJPfApPgg9MegdNgQhLfQhGdABIfQZEcgZB bQBFeQBCcwBAbgA8aQA6ZAA2XgAzZgAwUwAzWQAtTwAqSgAnQwAkPwAhOQAeMwAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAQUAP8ALAAAAADHAB4AAAf/gBEUFhcZGhsciYqLjI2Oj5CRkpOUlZaXmJmXHiImKi4LDA8SFRcY Gaipqqusra6vsLGys7S1tre4tRocICYsMQwNoxanGocbyMnKy8zNzs/Q0dLT1NXW19jRHJwnLDQ0 Dw+CFoaIHefo6err7O3u7/Dx8vP09fb38SAkKS4zOTkSJFAodegciIMIEypcyLChw4cQI0qcSLGi xYsQSZjg50+HjgoWCGXY0OGgCBIoU6pcybKly5cwY8qcSbOmzZs4XZYogWIFjBk4dPToYQoVSRAi dvJEwbSp06dQo0qdKuKChqlQNVzAyrVrhwsimGrtSras2bNOfdq4kaMHjx4Y/4xxKKmx6Yq7ePPq 3cu3r98VDgAI+Ku3AAC9IAIMIMz47gIAGO4abky5suXKLWDUuBG0h48ehrYh3biihenTqFOrXs26 9WkEAACIcI3aAIDUHQAEoM3bNAMAGUzb7k28uHHaL5K/kCHDBo4cOnh8Ds2J54rlzLNr3869u/fv 2QnEvgBeu23uHkqUX8+8AQANzM+zn0+/Pv3Nz6NPP9opRQv7ALK3AgAHAKAAcyY0sMEFFMiwQgIG NBAfACAccMAK7TVIgYQyNNCgDBQYcMAGCELIoXbukSiDfB0akAAICCrYgAEUPGgAjMyFOGKAPH63 1nND7UfXRv/1aKR2GwBwAf8ABjCXpG0SEhCAeA3aRoAABjLHpAwKAGCCDFlCAICUXsqApXgHogiA ivK5J2UAGCYZgG1MikcAc2KS+eWRRtbwY1uegXYUCUwVyaeR7pkgn5wUmABClgIcsKKXJmwJZpMU rJlkgwLcmaSCWR5AnpoJNNAAlsx1CiIAEMiQZAIyJAAApwCk6ikAJx4KoJ9sASqkPj0ZqmuABgTQ 4ZquAgCrDGKSuKd8lm75qIcUVsohk4/e2Z17sXUrQ6UHDgjrp8eSeJ61WjY57K5r/ROkoHQFuy6P c8qwZKvklmterZemq6UC7iUrgAG2NSmrARhul+KEyV7bJLkLn5fkwAXPax//r+4GOlK8pVls37Tf Kttwe8hmB626lhJ8wMNMmuohc10SkHB2C086cr8QIytxy6Z+6DF7GPsKL7Ad/zxfpt0KdnPNDPfr NIQGHJjvdmIuS3PJOzs8csS1Tm30fEG/uzHR2H1dXpcuY7lCvks2mECV/EarLgRztjrggYp+iKF4 CmNdq7ghS42rvufd/S2NZpcXtsaD9lR24t5defUF+VZ6YZYn+5tsyVeuIGajAkCwggDGqskmvwIM 5l6DOZvLb+efQ/7d4r9a97js2xGY3ZKgntilbl9m7jSY/NrbrbbixeYzyaczt2Rs2rZus/HQ4+7d Zr2KfVQJ/glrfYwqfttA/wUJhi9DBQ3siX57FbCfHQStZgdCA6Jnh775TqbP3Pr5V5Bw+a7SH/9k ML/6fW87NnBOxvbDCRMUrQYQjKAEJ0jBClrwghjMoAY3yMEOevCDIMTgnzwiHdDwglCZgWACV8jC FrrwhTCMoQxnSMMa2vCGOMyhDmN4gx7iIChCKaEGSuJAzaylhz78oRKXyMQmOvGJUIyiFKdIxSpa 8YpYzKIT/yEUt3xmAx4ggQp+wpkf/uOMaEyjGtfIxja68Y1wjKMc50jHOtoRjkGUzg944IERcMSM XPSIIAdJyEIa8pCITKQiF8nIRjrykZCMpCK96IMf7BEEJ+hHfro4lE568nyToAylKEdJylKa8pSo TKUqV8lKU/KAB5YEQhB8kEkaQCePr8ylLnfJy1768pfADKYwh0nMYhrzmMgkZiyDIIQfeANQ0vGB NKdJzWpa85rYzKY2t8nNbnrzm+AMpzi/+QNZCmEIQAAKdFrJzna6853wjKc8RZnLSgLBB4EAADs= ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/images/navbar3_01_02.gif R0lGODlhxwAeAOYAAP////H1+ODp79Pg6dDd58TV4cDS37PI2LDG16fA0qO90KC7z5SyyZCvxo2t xYOmwH+jvnObuHCYtmuVtGaRsWSQsGOOr12LrFeGqVKDp02ApEp9o0N4n0B1nTpymzdvmTZumDNm mSxokzNmmShkkihjjyVjkCFgjiBejB9bhxlaihhYhhhWhBBThBJPfApPgg9MegdNgQhLfQhGdABI fQZEcgZBbQBFeQBCcwBAbgA8aQA6ZAA2XgAzZgAzWQAwUwAtTwAqSgAnQwAkPwAhOQAeMwAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAQUAP8ALAAAAADHAB4AAAf/gBIWGBkbHB0eiYqLjI2Oj5CRkpOUlZaXmJmXICQoLDAODxEUFxka G6ipqqusra6vsLGys7S1tre4tRweIiguMw8QoxinHIcdyMnKy8zNzs/Q0dLT1NXW19jRHpwpLjY2 ERETg4aIH+fo6err7O3u7/Dx8vP09fb38SImKzA1OzsUKFgodeiciIMIEypcyLChw4cQI0qcSLGi xYsQTaDg548HjwsYCG3o8OEgCRMoU6pcybKly5cwY8qcSbOmzZs4XZ44oaKFjBo6ePjwYQoVSREk dvJUwbSp06dQo0qdStWpBQcQSDjlkEErU65do5LI8IHph7BV06pdy7btU584/3Ls8PHDhwZjHkpq bNqir9+/gAMLHky48N8EABIPOOE3AIAJfgskBpCA8V8NABz0dQBAg+HPoEOLHg34hYwbOYL6AOLD 0DakG1u8mE27tu3buHPr3m2bAgAGLyIAUDCbRGLisw0A2HAAwAHbGwA8mP1gOe/r2LNr3/4ihvcY NGjg0LGDxw/WrjnxbAE+vPv38OPLn0+/PnwCAdwLMBA+Q2IC7ikXHgEAtPAeBwBAEB4EAHBg34MQ RijhhPGhRp556B3VyQovUOjhh/IBwF94BobXAAAIFBiegDQw2MF7HSS4IAAv0iACAgZI4J4FENyI QAsZGNCAeygsYAAEJYKopP+HcZE3VIZ6bdThklRGKAIAQ8ZnAAEurgjAjDWGF6OCLdJIQwsBBEAg mcoRIAAABOAHQAZnCqAmAAtUqad9NzQ512qtHWUCU1PuaSh8Y4a4QKI0sKhckjTEeCQEyr1owZw0 2OklCigAIAANlyp4KZ0sHmoqDX3K9SeU+vRU6KmGMgojADqK6GUHKeY562SJvbiAiiei0OiXNNia 6K9gwnpoqv88Gaherip7qKzuSWAmfl4mZgCkkcpY5ossdsmisTIqZ4ABb4YpLZXMrvpsq7Ktuye1 4aUY3q/CVipsfIyKS6y/4ZGroHIQFAzBvvIu2a6zI0Ebb8JVougeAgq+yav/BcPS16+Z4XJMrMAZ Q7znwoA2DG97IispwKdnwtmCiAX/OmSp/HrbZbA0/GrguPwleqKBlKasJMmsDsqe0EoyiPGvEPiH ccAA0oyozWZeKgGaLPPcrYL+Xb0y0h8S/e56KIM9YQsE/tcCgyK4R2DI8m1cY9qYhgwyDXTTafaE qKnK8FEncPjq3hG2cAEEF4R3+HuHo7D4fChAUGMHB5MoQY/uPY44DZHXaLjkhE+Iw3jNltwBJyg8 fMPqrLfu+uuwxy777LTXbvvtuOeu++6z++nRea3xMqhpq49u/PHIJ6/88sw37/zz0Ecv/fTUV898 DtjrEJRQwHNQUuqnxYV97/bal2/++einr/767Lfv/vvwxy///PSn/49QdLF2ugks/JSa9v8IoAAH SMACGvCACEygAhfIwAY68IEQVCD3zhOEH4CgBBwB4P08wsEOevCDIAyhCEdIwhKa8IQoTKEKV0jC /AEhCBUUQQr6cSH8DeWGOMyhDnfIwx768IdADKIQh0jEIhoRiD/4AQyFMAQgzNAG5ZlgEqdIxSpa 8YpYzKIWt8jFLnrxi2AMoxi9uMQhECEI3vjTeYDAxja68Y1wjKMc50jHOtrxjnjMox73yMc8BoGJ RCiCEIBSniMa8pCITKQiF8lIHk7xhUIAQiAAADs= ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/images/navbar3_02_01.gif R0lGODlhxwAeAOYAAP////H1+ODp79Le6NDd58TV4cDS37DG16G7z6C7z5Cvxo2txYOmwH+jvnOb uHCYtm2WtWaRsWSQsGKOr1yKrFeGqVKDp06ApUp9o0N4n0B1nTpymzdvmjZumDNmmSxokzNmmShk kihjjyVjkCFgjiBejB9bhxlaihhYhhhWhBBThBJPfApPgg9MegdNgQhLfQhGdABIfQZEcgZBbQBF eQBCcwBAbgA8aQA6ZAA2XgAzZgAzWQAwUwAtTwAqSgAnQwAkPwAhOQAeMwAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAQUAP8ALAAAAADHAB4AAAf/gBATFRcYGRobiYqLjI2Oj5CRkpOUlZaXmJmXHSElKS0LDA4RFBaF GKipqqusra6vsLGys7S1tre4tBkbHyUrMAwNo4SGhxrHyMnKy8zNzs/Q0dLT1NXW19AbnCYrMzMO DoIVhogc5ufo6err7O3u7/Dx8vP09fbwHyMoLTI4OBERJlC4cMjch4MIEypcyLChw4cQI0qcSLGi xYsQR5TY1y9HDgoViGngcDDEiJMoU6pcybKly5cwY8qcSbOmzZstSZA4oeKFjBs5duwwhWrkhxA6 d55YyrSp06dQozrlsGABB6lYsWawkPWEBa5dl24NS7asWbI9a9jAsYPHDoK7/0hqZKqirt27ePPq 3YuXAoC/ACjwHcy3AADCGv5+IGzXMN4PAQYwnky5Ml8WL2jYALqjxw5D2o5uVMGitOnTqFOrXq16 QIAQHAAMYE2btQEAtSP8jVDb9G3UsQP0Hk68OGoXyF3EiFHjBo4cPDyD5rRThfLl2LNr3869O3cA BpYjUOC9vPfb5hX8JW9+OXrtHUi0n0+/fnnNzqFLN9oJBQv7AJoXQAAqaKdCAwYkUMJyKhyQwAcN aLBcAxNAGIMKCRjQgHsAfHDAAQVuR4ABARCAHYUWxoBgAgXe5iGIE04QgwYNLDjBhjFMYMABEl64 YogBBqmdWs4JtZ9cG/0n5P+Sy6l3gHYHgAeAAMslAAABAgCA45UBhEdAiQDIeBuWALCnXZnvxcBl eOrdlkAMY2bJHngxXBAmnCY+wCUAC1pJwJVMLkkDkWx19plRIyylZKBBqvDnm8uVUKaKAEgIqHpb annQpAI8eVsJkoanXWI3VrrcXw18EEOJMSQQAJx8hnpqeJJuCMCbApiYmK0mNoAjowAOulahR+bD 06LAAujorctNYOquH0xq55ZUxqCnhAvCOut2DXS466nVRrthtu/RqaaoXUr6QK3bDphtssGq5Y+R h8p1LLyN/rlhtyPq++23505oKnblippdlBcC8GTAM2qZXcHb4pnYMVMacFv/eM4KoCq+9Qk7r6EY IHovxwBC9mq3Cfga4b8OM9xtjxxGnF2XywlQrbkAx8ywud3q2bCGvsqY44Abk2yex8TWayxpRs9X wsZW0jjwcixvKerLDwMgc6SAAbYgzi3rbK65zjaga9jZRVtt094hTW/I9lrHdnmSLvyynRfUacBi zJYdsZ0yJiCm1gxjZ2fKCAKQt7kqMPsAeRAzHO2HCZNXggFCF6gezHNr5zbIIsvdeXdZLibAq40/ GeWCNjfYsrl1Nw454eZip162iZFXe+sEmBh57aguh6UKeoqpeoejb/d5sdVdl7x2dgImtHrrCazw 6wZTH8CCkRP8KoN01h69/+La7mzwbT2Ob2IM1DP7fHaaDfu2UST4h+z7kfr6bp0UZvfABCWIUIyy c6Ns3WiA2enfifYlNKoJMEc4UqAC+QckCD0ASDRqIP6Y05yP7YcTJWBaDGhAwhKa8IQoTKEKV8jC FrrwhTCMoQxnSEMWEsoj0fkMLxKFGRLW4IdADKIQh0jEIhrxiEhMohKXyMQmOvGJRbSBFG8AlKDk MAMkCWFm1CLFKVLxi2AMoxjHSMYymvGMaEyjGtfIxja6cYz+CEpbPKOBDowgBT7ZDBX9wcc++vGP gAykIAdJyEIa8pCITKQiF1lIK0bHBzzogAg4ssc4euSSmMykJjfJyU568pmToAylKEdJylKa8pNz 7IEPIPkBE/AjP3IUiixnScta2vKWuMylLnfJy1768pfADOYuecCDVf4ACD1w5Qye40hiOvOZ0Iym NKdJzWpa85rYzKY2t8nNbmbTmEAIgg+6Uajo9OCc6EynOtfJzna6853wjKc850nPetrznvT0wTGD IIQf/OQ5wgyoQAdK0IIa9KC3dKYqf9CDQAAAOw== ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/images/navbar3_02_02.gif R0lGODlhxwAeAOYAAP////D09+Dp79Dd58TV4cDS38DQ3LDG16C7z5CvxpCrv46uxYOmwH+jvnOb uHCYtm2WtWaRsWSQsGKOr12LrFeGqVKDp02ApEp9o0N4n0B1nTpymzdvmTZumDNmmSxokzNmmSll kihjjyVjkCFgjiBejB9bhxlaihhYhhhWhBBThBJPfApPgg9MegdNgQhLfQhGdABIfQZEcgZBbQBF eQBCcwBAbgA8aQA6ZAA2XgAzZgAwUwAzWQAtTwAqSgAnQwAkPwAhOQAeMwAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAQUAP8ALAAAAADHAB4AAAf/gBATFRYYGRobiYqLjI2Oj5CRkpOUlZaXmJmXHSElKS0LDA4RFBYX GKipqqusra6vsLGys7S1tre4tRkbHyUrMAwNoxWnGYcayMnKy8zNzs/Q0dLT1NXW19jRG5wmKzMz Dg6CFYaIHOfo6err7O3u7/Dx8vP09fb38R8jKC0yODgRIkwodejch4MIEypcyLChw4cQI0qcSLGi xYsQR5Tg5y9HDgoVCGHQwOFgiBEoU6pcybKly5cwY8qcSbOmzZs4XZIgcULFCxk3cvDgYQoVyQ8h dvI8wbSp06dQo0qdSrWqVA4WQjDNYGFqCAscrIodS7ZsWZ81bODgsYPHBWMb/0pqbKqirt27ePPq 3cu3r1++CwBcqEsAAN8LABb8Xcy4sePGLF7QsBGURw8ehrYh3aiChefPoEOLHk26tOnTpxkAwOC5 AIDSGAAwQE27tu3bp13odhEjRo0bOHLsuJyZE08VvHsrX868ufPn0KNLl94AQIberqFnANBguvfv 4MOHnwxcOPGjnVCwEM++vfvl1TVgB6Bcw4ECE3pr4N57woQPByTw3oAEepcWcEOdJ9dG6xXo4IO9 xTdfbx8AIIAAAOS3X3cxFFDAABg+AOGIA9Jw4FqWYXbUCEw1SOKL4lWHQAMNYNgbAoapEEABMWyI XQAWqAAAjzAW6Z2JaqGooP8+Pblo5JPPVQfAlFP2JgCR2fnYIX0xDBAAlGA2h+Q/CaooV5Nhpqmc hFv2BsCOBQRAn5bZtalmmGMqaSaTnd2ZJpt1WkgjjT3yZ2edfj6ZZ5kjndlnolACyuWQzNHJJaKQ wrhoio3ymVymRUra2wAD9BZgoRy6pkIMF4Ja5KZLsoicq6ECIJ+dCQBwEAAIoDrfAxX2SiuJsO55 3KfDQihqDCXI+WYJvm55wJS3JvvgZEkyehQJ6jlpbYEaNABtDBRwyOwD4vZWQgO3qvrABd9CWMNv ZHKqASclPErDvvz26++/AAcs8MAEF2wwwAYAcPDCDDfsMJLlmYcZLyxGtu//vBhnrPHGHHfs8ccg hyxyxwmPbPLJKKNsw8o3BCXUcDxkUFK+kqW1Msst56zzzjz37PPPQAct9NA5K2AA0UgnrfTSLf8j FFuX3TtCCj9R1vQ/WGet9dZcd+3112CHLfbYZJdt9tlgvzycDzt0IAJHVwfn0dx012333Xjnrffe fPft99+ABy743lD34APbH5jQT8RDNe7445BHLvnklFdu+eWYZ6755pxjvsMOh/8ARA+KzyA3W5+n rvrqrLfu+uuwxy777LTXbvvtuNceOhBB+OANisP1IPzwxBdv/PHIJ6/88sw37/zz0Ecv/fM+iB6E ED8AFVzn3Hfv/ffghy++COSpG/5DD4EAADs= ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/charent/Misc_Special_Characters/lowercase/lbull.gif R0lGODlhCgAKALMAAL29vbW1tbGxsampqWdnZ05OTikpKQwMDAgICAAAAP///wAAAAAAAAAAAAAA AAAAACH5BAUUAAoALAAAAAAKAAoAAAQsUKlQDiJAqmFQSogxKIDxnYkBEB4Ksu6JHPF3FK1bBKZr CJvOJzSSUCwYSQQAOw== ------=_NextPart_000_0000_01C868D9.A4078F90 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://arpa.allenpress.com/images/indent.gif R0lGODlhCgAKAPEAAP////8AAAAAAAAAACH5BAEAAAAALAAAAAAKAAoAQQIJhI+py+0PIyMoADs= ------=_NextPart_000_0000_01C868D9.A4078F90--