BRAIN TUMOR LIBRARY
Glioblastoma | Etiology, Pathogenesis, Pathology
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Home > Brain tumor library > Diffuse astrocytic and oligodendroglial tumors > Glioblastoma > Etiology, Pathogenesis, Pathology


CONTENTS

BEVACIZUMAB
CYTOMEGALOVIRUS
DNA REPAIR MECHANISMS
IMMUNE SYSTEM
STEM CELLS
SUBGROUPS
SUBVENTRICULAR ZONE
TAMOXIFEN
TUMOR TREATING FIELDS
VALPROIC ACID
VINCRISTINE

PATHOLOGY
RECURRENCE
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Radiotherapy as inducer
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Surgery as inducer
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Tumor network
TUMOR BIOLOGY

CHOLESTEROL
HEPATITIS C
PRIOR CANCER

MOLECULAR CHARACTERISTICS
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Congenital glioblastoma








BEVACIZUMAB



Baumgarten P, Blank AE, Franz K, Hattingen E, Dunst M, Zeiner P, Hoffmann K, Bähr O, Mäder L, Goeppert B, Machein M, Seifert V, Steinbach JP, Plate KH, Harter PN, Mittelbronn M.
Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.
Neuro Oncol. 2016 Feb;18(2):173-83. doi: 10.1093/neuonc/nov288. Epub 2015 Nov 30.
Source | Abstract | Full text | Similar articles




Okamoto S, Nitta M, Maruyama T, Sawada T, Komori T, Okada Y, Muragaki Y.
Bevacizumab changes vascular structure and modulates the expression of angiogenic factors in recurrent malignant gliomas.
Brain Tumor Pathol. 2016 Apr;33(2):129-36. doi: 10.1007/s10014-016-0248-6. Epub 2016 Jan 29.
Source | Abstract | Full text | Similar articles





CHOLESTEROL



An Z, Weiss WA.
Cholesterol: An Achilles' Heel for Glioblastoma?
Cancer Cell. 2016 Nov 14;30(5):653-654. doi: 10.1016/j.ccell.2016.10.011.
Source | Abstract | Full text | Similar articles



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Villa GR, Hulce JJ, Zanca C, Bi J, Ikegami S, Cahill GL, Gu Y, Lum KM, Masui K, Yang H, Rong X, Hong C, Turner KM, Liu F, Hon GC, Jenkins D, Martini M, Armando AM, Quehenberger O, Cloughesy TF, Furnari FB, Cavenee WK, Tontonoz P, Gahman TC, Shiau AK, Cravatt BF, Mischel PS.
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.
Cancer Cell. 2016 Nov 14;30(5):683-693. doi: 10.1016/j.ccell.2016.09.008. Epub 2016 Oct 13.
Source | Abstract | Full text | Similar articles





CYTOMEGALOVIRUS



McFaline-Figueroa JR, Wen PY.
The Viral Connection to Glioblastoma.
Curr Infect Dis Rep. 2017 Feb 23;19(2):5. doi: 10.1007/s11908-017-0563-z.
Source | Abstract | Full text | Similar articles




Taha MS, Abdalhamid BA, El-Badawy SA, Sorour YM, Almsned FM, Al-Abbadi MA.
Expression of cytomegalovirus in glioblastoma multiforme: Myth or reality?
Br J Neurosurg. 2016 Jun;30(3):307-12. doi: 10.3109/02688697.2015.1119241. Epub 2016 Jan 8.
Source | Abstract | Full text | Similar articles





DNA REPAIR MECHANISMS



Erasimus H, Gobin M, Niclou S, Van Dyck E.
DNA repair mechanisms and their clinical impact in glioblastoma.
Mutat Res Rev Mutat Res. 2016 Jul-Sep;769:19-35. doi: 10.1016/j.mrrev.2016.05.005. Epub 2016 Jun 21.
Source | Abstract | Full text | Similar articles





HEPATITIS C



Kostic M.
From Glioblastoma to Hepatitis C: It's a Metabolism Thing.
Cell Chem Biol. 2016 Nov 17;23(11):1315-1316. doi: 10.1016/j.chembiol.2016.11.005.
Source | Abstract | Full text | Similar articles





IMMUNE SYSTEM



Rahme RJ, Aoun RJ, Pines AR, Swanson KR, Bendok BR.
Defining the Immune Phenotype for Glioblastoma Multiforme: One Step Closer to Understanding Our Enemy.
World Neurosurg. 2016 Aug 23. pii: S1878-8750(16)30731-8. doi: 10.1016/j.wneu.2016.08.063. [Epub ahead of print]
Source | Abstract | Full text | Similar articles





MOLECULAR CHARACTERISTICS



CONGENITAL GLIOBLASTOMA


Kameda M, Otani Y, Ichikawa T, Shimada A, Ichimura K, Date I.
Congenital Glioblastoma with Distinct Clinical and Molecular Characteristics: Case Reports and a Literature Review.
World Neurosurg. 2017 May;101:817.e5-817.e14. doi: 10.1016/j.wneu.2017.02.026. Epub 2017 Feb 16.
Source | Abstract | Full text | Similar articles





PATHOLOGY



Regazzo G, Terrenato I, Spagnuolo M, Carosi M, Cognetti G, Cicchillitti L, Sperati F, Villani V, Carapella C, Piaggio G, Pelosi A, Rizzo MG.
A restricted signature of serum miRNAs distinguishes glioblastoma from lower grade gliomas.
J Exp Clin Cancer Res. 2016 Jul 30;35(1):124. doi: 10.1186/s13046-016-0393-0.
Source | Abstract | Full text | Similar articles




Rodriguez FJ, Vizcaino MA, Lin MT.
Recent Advances on the Molecular Pathology of Glial Neoplasms in Children and Adults.
J Mol Diagn. 2016 Sep;18(5):620-34. doi: 10.1016/j.jmoldx.2016.05.005.
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NECROSIS


Raza SM, Lang FF, Aggarwal BB, Fuller GN, Wildrick DM, Sawaya R.
Necrosis and Glioblastoma: A Friend or a Foe? A Review and a Hypothesis
Neurosurgery. 2002 Jul;51(1):2-12; discussion 12-3.

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SMALL CELL GBM


Takeuchi H, Kitai R, Hosoda T, Yamada S, Hashimoto N, Kikuta K, Shimizu Y, Kimura H.
Clinicopathologic features of small cell glioblastomas.
J Neurooncol. 2016 Apr;127(2):337-44. doi: 10.1007/s11060-015-2038-0. Epub 2016 Jan 2.
Source | Abstract | Full text | Similar articles





PRIOR CANCER


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Zacharia BE, DiStefano N, Mader MM, Chohan MO, Ogilvie S, Brennan C, Gutin P, Tabar V.
Prior malignancies in patients harboring glioblastoma: an institutional case-study of 2164 patients.
J Neurooncol. 2017 May 27. doi: 10.1007/s11060-017-2512-y. [Epub ahead of print]
Source | Abstract | Full text | Similar articles





RECURRENCE


**

Lin Q, Liu Z, Ling F, Xu G.
Astrocytes protect glioma cells from chemotherapy and upregulate survival genes via gap junctional communication.
Mol Med Rep. 2015 Dec 11. doi: 10.3892/mmr.2015.4680. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



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Osuka S, Van Meir EG.
Overcoming therapeutic resistance in glioblastoma: the way forward.
J Clin Invest. 2017 Feb 1;127(2):415-426. doi: 10.1172/JCI89587. Epub 2017 Feb 1.
Source | Abstract | Full text | Similar articles




Qazi MA, Vora P, Venugopal C, Sidhu SS, Moffat J, Swanton C, Singh SK.
Intratumoral Heterogeneity: Pathways to Treatment Resistance and Relapse in Human Glioblastoma.
Ann Oncol. 2017 Apr 12. doi: 10.1093/annonc/mdx169. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Soheila RD, Alessandro R, Hambra DV, Danilo P, Sabino L, Paola P, Benedetta C, Tempesta D, Coletti G, Cipolloni G, Grazia CM, Renato G.
Stemness Markers Detection In The Periphery Of Glioblastomas And Glioblastoma Ability To Generate Glioma Stem Cells: Clinical Correlations.
World Neurosurg. 2017 May 27. pii: S1878-8750(17)30798-2. doi: 10.1016/j.wneu.2017.05.099. [Epub ahead of print]
Source | Abstract | Full text | Similar articles | Editor's choice




Wood MD, Reis GF, Reuss DE, Phillips JJ.
Protein Analysis of Glioblastoma Primary and Posttreatment Pairs Suggests a Mesenchymal Shift at Recurrence.
J Neuropathol Exp Neurol. 2016 Aug 18. pii: nlw068. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




RADIOTHERAPY AS AN INDUCER OF TUMOR RECURRENCE


Baulch JE, Geidzinski E, Tran KK, Yu L, Zhou YH, Limoli CL.
Irradiation of primary human gliomas triggers dynamic and aggressive survival responses involving microvesicle signaling.
Environ Mol Mutagen. 2015 Nov 25. doi: 10.1002/em.21988. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Falk AT, Moncharmont C, Guilbert M, Guy JB, Alphonse G, Trone JC, Rivoirard R, Gilormini M, Toillon RA, Rodriguez-Lafrasse C, Magné N.
Radiation-induces increased tumor cell aggressiveness of tumors of the glioblastomas?
Bull Cancer. 2014 Sep 1;101(9):876-880.
Source | Abstract | Full text | Similar articles




SURGERY AS AN INDUCER OF TUMOR RECURRENCE


Burda JE, Sofroniew MV.
Reactive gliosis and the multicellular response to CNS damage and disease.
Neuron. 2014 Jan 22;81(2):229-48. doi: 10.1016/j.neuron.2013.12.034.
Source | Abstract | Full text | Similar articles




Demicheli R, Retsky MW, Hrushesky WJ, Baum M, Gukas ID.
The effects of surgery on tumor growth: a century of investigations.
Ann Oncol. 2008 Nov;19(11):1821-8. doi: 10.1093/annonc/mdn386.
Source | Abstract | Full text | Similar articles




Hamard L, Ratel D, Selek L, Berger F, van der Sanden B, Wion D.
The brain tissue response to surgical injury and its possible contribution to glioma recurrence.
J Neurooncol. 2016 May;128(1):1-8. doi: 10.1007/s11060-016-2096-y. Epub 2016 Mar 9.
Source | Abstract | Full text | Similar articles




Kong B, Michalski CW, Friess H, Kleeff J.
Surgical procedure as an inducer of tumor angiogenesis.
Exp Oncol. 2010 Sep;32(3):186-9.
Source | Abstract | Full text | Similar articles




Lemée JM, Clavreul A, Menei P.
Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone.
Neuro Oncol. 2015 Oct;17(10):1322-32. doi: 10.1093/neuonc/nov119. Epub 2015 Jul 22.
Source | Abstract | Full text | Similar articles




McDonald JT, Gao X, Steber C, Lee Breed J, Pollock C, Ma L, Hlatky L.
Host mediated inflammatory influence on glioblastoma multiforme recurrence following high-dose ionizing radiation.
PLoS One. 2017 May 22;12(5):e0178155. doi: 10.1371/journal.pone.0178155. eCollection 2017.
Source | Abstract | Full text | Similar articles




Menei P, Clavreul A, Lemée JM.
Response to "Glioma resection and tumor recurrence: back to Semmelweis".
Neuro Oncol. 2016 Dec;18(12):1689. Epub 2016 Oct 7.
Source | Abstract | Full text | Similar articles



***

Okolie O, Bago JR, Schmid RS, Irvin DM, Bash RE, Miller CR, Hingtgen SD.
Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.
Neuro Oncol. 2016 Dec;18(12):1622-1633. Epub 2016 Jun 13.
Source | Abstract | Full text | Similar articles




Predina J, Eruslanov E, Judy B, Kapoor V, Cheng G, Wang LC, Sun J, Moon EK, Fridlender ZG, Albelda S, Singhal S.
Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery.
Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E415-24. doi: 10.1073/pnas.1211850110. Epub 2012 Dec 27.
Source | Abstract | Full text | Similar articles



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Qi XT, Zhan JS, Xiao LM, Li L, Xu HX, Fu ZB, Zhang YH, Zhang J, Jia XH, Ge G, Chai RC, Gao K, Yu ACH.
The Unwanted Cell Migration in the Brain: Glioma Metastasis.
Neurochem Res. 2017 Jun;42(6):1847-1863. doi: 10.1007/s11064-017-2272-2. Epub 2017 May 6.
Source | Abstract | Full text | Similar articles



***

Ratel D, van der Sanden B, Wion D.
Glioma resection and tumor recurrence: back to Semmelweis.
Neuro Oncol. 2016 Dec;18(12):1688-1689. Epub 2016 Oct 7
Source | Abstract | Full text | Similar articles



**

Wion D.
Therapeutic dormancy to delay postsurgical glioma recurrence: the past, present and promise of focal hypothermia.
J Neurooncol. 2017 May 17. doi: 10.1007/s11060-017-2471-3. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Wion D, Appaix F, Burruss M, Berger F, van der Sanden B.
Cancer research in need of a scientific revolution: Using 'paradigm shift' as a method of investigation.
J Biosci. 2015 Sep;40(3):657-66. Epub 2015 Jul 17
Source | Abstract | Full text | Similar articles




TUMOR NETWORK


Malkki H.
Neuro-oncology: Astrocytoma cells interconnect to resist radiotherapy.
Nat Rev Neurol. 2015 Dec;11(12):668. doi: 10.1038/nrneurol.2015.215. Epub 2015 Nov 20.
Source | Abstract | Full text | Similar articles



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Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Blaes J, Weil S, Horstmann H, Wiestler B, Syed M, Huang L, Ratliff M, Karimian Jazi K, Kurz FT, Schmenger T, Lemke D, Gömmel M, Pauli M, Liao Y, Häring P, Pusch S, Herl V, Steinhäuser C, Krunic D, Jarahian M, Miletic H, Berghoff AS, Griesbeck O, Kalamakis G, Garaschuk O, Preusser M, Weiss S, Liu H, Heiland S, Platten M, Huber PE, Kuner T, von Deimling A, Wick W, Winkler F.
Brain tumour cells interconnect to a functional and resistant network.
Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071. Epub 2015 Nov 4.
Source | Abstract | Full text | Similar articles




Shipman L.
Glioma: Tumour cell teamwork.
Nat Rev Cancer. 2016 Jan;16(1):2. doi: 10.1038/nrc.2015.7. Epub 2015 Dec 4.
Source | Abstract | Full text | Similar articles




Sontheimer H.
Brain cancer: Tumour cells on neighbourhood watch.
Nature. 2015 Dec 3;528(7580):49-50. doi: 10.1038/nature15649. Epub 2015 Nov 4.
Source | Abstract | Full text | Similar articles




Winkler F.
Tumour network in glioma.
ESMO Open. 2016 Dec 19;1(6):e000133. doi: 10.1136/esmoopen-2016-000133.
Source | Abstract | Full text | Similar articles





STEM CELLS



Bradshaw A, Wickremesekera A, Brasch HD, Chibnall AM, Davis PF, Tan ST, Itinteang T.
Cancer Stem Cells in Glioblastoma Multiforme.
Front Surg. 2016 Aug 26;3:48. doi: 10.3389/fsurg.2016.00048.
Source | Abstract | Full text | Similar articles




D'Alessio A, Proietti G, Lama G, Biamonte F, Lauriola L, Moscato U, Vescovi A, Mangiola A, Angelucci C, Sica G.
Analysis of angiogenesis related factors in glioblastoma, peritumoral tissue and their derived cancer stem cells.
Oncotarget. 2016 Oct 1. doi: 10.18632/oncotarget.12398. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



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Munthe S, Sørensen MD, Thomassen M, Burton M, Kruse TA, Lathia JD, Poulsen FR, Kristensen BW.
Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting.
J Neurooncol. 2016 Oct;130(1):53-62. Epub 2016 Aug 10.
Source | Abstract | Full text | Similar articles




Orzan F, De Bacco F, Crisafulli G, Pellegatta S, Mussolin B, Siravegna G, D'ambrosio A, Comoglio PM, Finocchiaro G, Boccaccio C.
Genetic Evolution of Glioblastoma Stem-like Cells from Primary to Recurrent Tumor.
Stem Cells. 2017 Sep 12. doi: 10.1002/stem.2703. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Parada LF, Dirks PB, Wechsler-Reya RJ.
Brain Tumor Stem Cells Remain in Play.
J Clin Oncol. 2017 Jun 22:JCO2017739540. doi: 10.1200/JCO.2017.73.9540. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Rennert RC, Achrol AS, Januszyk M, Kahn SA, Liu TT, Liu Y, Sahoo D, Rodrigues M, Maan ZN, Wong VW, Cheshier SH, Chang SD, Steinberg GK, Harsh GR, Gurtner GC.
Multiple Subsets of Brain Tumor Initiating Cells Coexist in Glioblastoma.
Stem Cells. 2016 Jun;34(6):1702-7. doi: 10.1002/stem.2359. Epub 2016 Mar 28.
Source | Abstract | Full text | Similar articles




Schiffer D, Annovazzi L, Mellai M.
A comprehensive view of tumor stem cells and their regulation by the microenvironment in glioblastoma.
Neurol Sci. 2016 Nov 16. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Wang W, Liu F, Xiang B, Xiang C, Mou X.
Stem cells as cellular vehicles for gene therapy against glioblastoma.
Int J Clin Exp Med. 2015 Oct 15;8(10):17102-9. eCollection 2015.
Source | Abstract | Full text | Similar articles





SUBGROUPS



Arita H, Yamasaki K, Matsushita Y, Nakamura T, Shimokawa A, Takami H, Tanaka S, Mukasa A, Shirahata M, Shimizu S, Suzuki K, Saito K, Kobayashi K, Higuchi F, Uzuka T, Otani R, Tamura K, Sumita K, Ohno M, Miyakita Y, Kagawa N, Hashimoto N, Hatae R, Yoshimoto K, Shinojima N, Nakamura H, Kanemura Y, Okita Y, Kinoshita M, Ishibashi K, Shofuda T, Kodama Y, Mori K, Tomogane Y, Fukai J, Fujita K, Terakawa Y, Tsuyuguchi N, Moriuchi S, Nonaka M, Suzuki H, Shibuya M, Maehara T, Saito N, Nagane M, Kawahara N, Ueki K, Yoshimine T, Miyaoka E, Nishikawa R, Komori T, Narita Y, Ichimura K.
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
Acta Neuropathol Commun. 2016 Aug 8;4(1):79. doi: 10.1186/s40478-016-0351-2.
Source | Abstract | Full text | Similar articles




Evans C.
TCGA Scientists Discover Four Distinct Subtypes of Glioblastoma Distinguished by Gene Expression Patterns and Clinical Characteristics
The Cancer Genome Atlas, Posted: February 1, 2011
Comment on: Verhaak RG et al. (2010), Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
Source | Abstract | Full text | Similar articles




Sidaway P.
CNS cancer: Glioblastoma subtypes revisited.
Nat Rev Clin Oncol. 2017 Aug 1. doi: 10.1038/nrclinonc.2017.122. [Epub ahead of print]
Comment on: Wang Q et al., Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Source | Abstract | Full text | Similar articles




Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN; Cancer Genome Atlas Research Network.
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
Cancer Cell. 2010 Jan 19;17(1):98-110. doi: 10.1016/j.ccr.2009.12.020.
Source | Abstract | Full text | Similar articles




Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW.
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Cancer Cell. 2017 Jul 10;32(1):42-56.e6. doi: 10.1016/j.ccell.2017.06.003.
Source | Abstract | Full text | Similar articles





SUBVENTRICULAR ZONE



Capdevila C, Rodríguez Vázquez L, Martí J.
Glioblastoma Multiforme and Adult Neurogenesis in the Ventricular-Subventricular Zone: A Review.
J Cell Physiol. 2016 Jul 26. doi: 10.1002/jcp.25502. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Gollapalli K, Ghantasala S, Kumar S, Srivastava R, Rapole S, Moiyadi A, Epari S, Srivastava S.
Subventricular zone involvement in Glioblastoma - A proteomic evaluation and clinicoradiological correlation.
Sci Rep. 2017 May 3;7(1):1449. doi: 10.1038/s41598-017-01202-8.
Source | Abstract | Full text | Similar articles





TAMOXIFEN



Graham CD, Kaza N, Klocke BJ, Gillespie GY, Shevde LA, Carroll SL, Roth KA.
Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma.
J Neuropathol Exp Neurol. 2016 Aug 11. pii: nlw071. [Epub ahead of print]
Source | Abstract | Full text | Similar articles





TUMOR BIOLOGY



Ho IAW, Shim WSN.
Contribution of the Microenvironmental Niche to Glioblastoma Heterogeneity.
Biomed Res Int. 2017;2017:9634172. doi: 10.1155/2017/9634172. Epub 2017 May 28.
Source | Abstract | Full text | Similar articles




Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN.
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature. 2017 Jul 5. doi: 10.1038/nature23000. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Northcott PA.
Cancer: Keeping it real to kill glioblastoma.
Nature. 2017 Jul 5. doi: 10.1038/nature23095. [Epub ahead of print]
Source | Abstract | Full text | Similar articles





TUMOR TREATING FIELDS



Kim EH, Song HS, Yoo SH, Yoon M.
Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis.
Oncotarget. 2016 Aug 18. doi: 10.18632/oncotarget.11372. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Kim EH, Kim YJ, Song HS, Jeong YK, Lee JY, Sung J, Yoo SH, Yoon M.
Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation.
Oncotarget. 2016 Aug 19. doi: 10.18632/oncotarget.11407. [Epub ahead of print]
Source | Abstract | Full text | Similar articles




Wenger C, Giladi M, Bomzon Z, Salvador R, Basser PJ, Miranda PC.
Modeling Tumor Treating Fields (TTFields) application in single cells during metaphase and telophase.
Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:6892-5. doi: 10.1109/EMBC.2015.7319977.
Source | Abstract | Full text | Similar articles





VINCRISTINE



Park KJ, Yu MO, Park DH, Park JY, Chung YG, Kang SH.
Role of vincristine in the inhibition of angiogenesis in glioblastoma.
Neurol Res. 2016 Jul 25:1-9. [Epub ahead of print]
Source | Abstract | Full text | Similar articles