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Medulloblastoma | Etiology, Pathogenesis, Pathology
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EXTRANEURAXIAL METASTASES



Gupta T, Dasgupta A, Epari S, Shirsat N, Chinnaswamy G, Jalali R.
Extraneuraxial metastases in medulloblastoma: is histology and molecular biology important?
J Neurooncol. 2017 Jul 28. doi: 10.1007/s11060-017-2586-6. [Epub ahead of print]
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PROGRESSION



Liu Y, Yuelling LW, Wang Y, Du F, Gordon RE, O'Brien J, Ng JMY, Robins S, Lee EH, Liu H, Curran T, Yang ZJ.
Astrocytes promote medulloblastoma progression through hedgehog secretion.
Cancer Res. 2017 Oct 6. pii: canres.1463.2017. doi: 10.1158/0008-5472.CAN-17-1463. [Epub ahead of print]
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SUBGROUPS



Benmaamar R.
Redefining the molecular substructure of medulloblastoma.
Comment on: Northcott PA, The whole-genome landscape of medulloblastoma subtypes.
Lancet Oncol. 2017 Sep;18(9):e514. doi: 10.1016/S1470-2045(17)30571-5. Epub 2017 Jul 27.
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Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nor C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, Daniels C, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska WA, Perek-Polnik M, Vasiljevic A, Faure-Conter C, Jouvet A, Giannini C, Nageswara Rao AA, Li KKW, Ng HK, Eberhart CG, Pollack IF, Hamilton RL, Gillespie GY, Olson JM, Leary S, Weiss WA, Lach B, Chambless LB, Thompson RC, Cooper MK, Vibhakar R, Hauser P, van Veelen MC, Kros JM, French PJ, Ra YS, Kumabe T, López-Aguilar E, Zitterbart K, Sterba J, Finocchiaro G, Massimino M, Van Meir EG, Osuka S, Shofuda T, Klekner A, Zollo M, Leonard JR, Rubin JB, Jabado N, Albrecht S, Mora J, Van Meter TE, Jung S, Moore AS, Hallahan AR, Chan JA, Tirapelli DPC, Carlotti CG, Fouladi M, Pimentel J, Faria CC, Saad AG, Massimi L, Liau LM, Wheeler H, Nakamura H, Elbabaa SK, Perezpeña-Diazconti M, Chico Ponce de León F, Robinson S, Zapotocky M, Lassaletta A, Huang A, Hawkins CE, Tabori U, Bouffet E, Bartels U, Dirks PB, Rutka JT, Bader GD, Reimand J, Goldenberg A, Ramaswamy V, Taylor MD.
Intertumoral Heterogeneity within Medulloblastoma Subgroups.
Cancer Cell. 2017 Jun 12;31(6):737-754.e6. doi: 10.1016/j.ccell.2017.05.005.
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Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, Waszak SM, Erkek S, Jones DTW, Worst BC, Kool M, Zapatka M, Jäger N, Chavez L, Hutter B, Bieg M, Paramasivam N, Heinold M, Gu Z, Ishaque N, Jäger-Schmidt C, Imbusch CD, Jugold A, Hübschmann D, Risch T, Amstislavskiy V, Gonzalez FGR, Weber UD, Wolf S, Robinson GW, Zhou X, Wu G, Finkelstein D, Liu Y, Cavalli FMG, Luu B, Ramaswamy V, Wu X, Koster J, Ryzhova M, Cho YJ, Pomeroy SL, Herold-Mende C, Schuhmann M, Ebinger M, Liau LM, Mora J, McLendon RE, Jabado N, Kumabe T, Chuah E, Ma Y, Moore RA, Mungall AJ, Mungall KL, Thiessen N, Tse K, Wong T, Jones SJM, Witt O, Milde T, Von Deimling A, Capper D, Korshunov A, Yaspo ML, Kriwacki R, Gajjar A, Zhang J, Beroukhim R, Fraenkel E, Korbel JO, Brors B, Schlesner M, Eils R, Marra MA, Pfister SM, Taylor MD, Lichter P.
The whole-genome landscape of medulloblastoma subtypes.
Nature. 2017 Jul 19;547(7663):311-317. doi: 10.1038/nature22973.
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Ramaswamy V, Taylor MD.
Medulloblastoma: From Myth to Molecular.
J Clin Oncol. 2017 Jun 22:JCO2017727842. doi: 10.1200/JCO.2017.72.7842. [Epub ahead of print]
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Schwalbe EC, Lindsey JC, Nakjang S, Crosier S, Smith AJ, Hicks D, Rafiee G, Hill RM, Iliasova A, Stone T, Pizer B, Michalski A, Joshi A, Wharton SB, Jacques TS, Bailey S, Williamson D, Clifford SC.
Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study.
Lancet Oncol. 2017 May 22. pii: S1470-2045(17)30243-7. doi: 10.1016/S1470-2045(17)30243-7. [Epub ahead of print]
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Sengupta S, Pomeranz Krummel D, Pomeroy S.
The evolution of medulloblastoma therapy to personalized medicine.
F1000Res. 2017 Apr 13;6:490. doi: 10.12688/f1000research.10859.1. eCollection 2017.
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Taylor MD, Northcott PA, Korshunov A, Remke M, Cho YJ, Clifford SC, Eberhart CG, Parsons DW, Rutkowski S, Gajjar A, Ellison DW, Lichter P, Gilbertson RJ, Pomeroy SL, Kool M, Pfister SM.
Molecular subgroups of medulloblastoma: the current consensus.
Acta Neuropathol. 2012 Apr;123(4):465-72. doi: 10.1007/s00401-011-0922-z. Epub 2011 Dec 02
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