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27 April 2006
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Edward R. Winstead
Brain Cancer Study Supports
Fluorescence-Guided Surgery
NCI Cancer Bulletin, May 9, 2006, Volume 3, Number 19
News
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Reuters Health
Fluorescence-guided
surgery improves glioma survival
OncoLink, 27 April 2006
News
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Walter Stummer,
Uwe Pichlmeier, Thomas Meinel,
Otmar Dieter Wiestler, Friedhelm Zanella
and Hans-Jürgen Reulen, for the
ALA-Glioma Study Group
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of
malignant glioma: a randomised controlled multicentre phase III trial
The Lancet Oncology,
Volume 7,
Number 5, May
2006, pp 392-401; DOI:10.1016/S1470-2045(06)70665-9
Abstract
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News
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(American Association of Neurological
Surgeons annual meeting)
Reuters Health
Language
mapping aids in speech preservation with glioma resection
OncoLink, 27 April 2006
News
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Eileen Scahill
Arthritis
drug might reduce fatigue in cancer patients
Ohio State University, Research News, 24 April 2006
News
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J. Paul Monk, Gary
Phillips, Ross Waite, John Kuhn, Larry
J. Schaaf, Gregory A. Otterson, Denis Guttridge,
Chris Rhoades, Manisha Shah, Tamara
Criswell, Michael A. Caligiuri, Miguel A.
Villalona-Calero
Assessment of
Tumor Necrosis Factor Alpha Blockade As an Intervention to Improve
Tolerability of Dose-Intensive Chemotherapy in Cancer Patients
Journal of Clinical Oncology, Vol 24, No 12 (April 20), 2006: pp.
1852-1859 - DOI: 10.1200/JCO.2005.04.2838
Abstract
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Megan Rauscher
Timed
meals and chemo may boost anti-cancer therapy
OncoLink, 27 April 2006
News
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Alec
J. Davidson, Martin Straume, Gene D. Block, Michael Menaker
Daily
timed meals dissociate circadian rhythms in hepatoma and healthy host
liver
Int
Journal of Cancer, Volume
118, Issue 7, Pages 1623 – 1627 (1 April 2006); Published Online: 17 Oct
2005;
DOI:
10.1002/ijc.21591
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26 April 2006
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Jennifer Michalowski
Better
model of deadly brain cancer
EurekAlert!, 26 April 2006
News
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Catherine T. Yan, Dhruv Kaushal, Michael
Murphy, Yu Zhang, Abhishek Datta, Changzhong Chen, Brianna Monroe, Gustavo
Mostoslavsky, Kristen Coakley, Yijie Gao, Kevin D. Mills, Alex P. Fazeli,
Suprawee Tepsuporn, Giles Hall, Richard Mulligan, Edward Fox, Roderick
Bronson, Umberto De Girolami, Charles Lee, and Frederick W. Alt
XRCC4 suppresses medulloblastomas with recurrent translocations in
p53-deficient mice
Proc. Natl. Acad. Sci. USA,
Published online before print May
2, 2006; 10.1073/pnas.0601938103
Abstract
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Amy Adams
Stanford
scientists identify protein involved in fast-spreading cancers
EurekAlert!, 26 April 2006
News
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Janine T. Erler, Kevin L. Bennewith,
Monica Nicolau, Nadja Dornhöfer, Christina Kong, Quynh-Thu Le, Jen-Tsan
Ashley Chi, Stefanie S. Jeffrey and Amato J. Giaccia
Lysyl
oxidase is essential for hypoxia-induced metastasis
Nature, 440, 1222-1226 (27 April 2006); doi:10.1038/nature04695
Abstract
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25 April 2006
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Laura Sussman
Study
finds novel vaccine curbs brain tumor growth, increases survival
EurekAlert!, 25 April 2006
News
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24 April 2006
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Elizabeth McCrocklin
Weizmann
Institute Scientists Create a Method for Predicting Chemotherapy Success
That Indicates how Easily the Drug can be Delivered Into the Tumor
Weizmann Institute, News Releases, 24 April 2006
News
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Yaron Hassid, Edna Furman-Haran,
Raanan Margalit, Raya Eilam and Hadassa Degani
Noninvasive
Magnetic Resonance Imaging of Transport and Interstitial Fluid Pressure in
Ectopic Human Lung Tumors
Cancer Research, 66, 4159-4166, April 15, 2006
Abstract
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Thomas Rosol
Nanotechnology
may find disease before it starts
Ohio State University, Research News, 24 April 2006
News
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Jun
Liu, Andrea L Levine, John S Mattoon, Mamoru Yamaguchi, Robert J Lee,
Xueliang Pan and Thomas J Rosol
Nanoparticles
as image enhancing agents for ultrasonography
Phys. Med. Biol.,
2006 May 7;51(9):2179-89; Epub 2006 Apr 10; doi:10.1088/0031-9155/51/9/004
Abstract
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Paul Preuss
Revealing
the Secrets of WRN.
The Unique Protein Responsible for Werner's Syndrome Aids Research in
Cancer and Aging
Berkeley Lab Research News, 24 April 2006
News
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J Jefferson P Perry,
Steven M Yannone, Lauren G Holden, Chiharu Hitomi, Aroumougame Asaithamby,
Seungil Han, Priscilla K Cooper, David J Chen & John A Tainer
WRN exonuclease structure and
molecular mechanism imply an editing role in DNA end processing
Nature Structural & Molecular Biology, Published
online: 23 April 2006; doi:10.1038/nsmb1088
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23 April 2006
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Dr Branwen Morgan
Cancer
cells suppress large regions of DNA by a reversible process that can be
tackled
EurekAlert!, 23 April 2006
News
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Jordi Frigola,
Jenny Song, Clare Stirzaker, Rebecca A Hinshelwood, Miguel A Peinado
& Susan J Clark
Epigenetic
remodeling in colorectal cancer results in coordinate gene suppression
across an entire chromosome band
Nature Genetics, 38, 540 - 549
(2006), Published online: 23 April 2006; doi:10.1038/ng1781
Abstract
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20 April 2006
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Darrell E. Ward
Viral
protein helps infected T cells stick to uninfected cells
The Ohio State University, Research News, 20 April 2006
News
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Seung-jae Kim, Amrithraj
M. Nair, Soledad Fernandez, Lawrence Mathes
and Michael D. Lairmore
Enhancement
of LFA-1-Mediated T Cell Adhesion by Human T Lymphotropic Virus Type 1 p12I
The Journal of Immunology, 2006, 176: 5463-5470, 1 May 2006
Abstract
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Brad Allan
Discovery
points to more effective ways of regulating cell signalling
The
Walter And Eliza Hall Institute Of Medical Research, Media Release, 20
April 2006
News
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Jeffrey
J. Babon, Edward
J. McManus, Shenggen Yao,
David P. DeSouza, Lisa
A. Mielke, Naomi S. Sprigg,
Tracy A. Willson, Douglas
J. Hilton, Nicos
A. Nicola, Manuel Baca,
Sandra E. Nicholson, and
Raymond
S. Norton
The
Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function
and Identifies an Unstructured Insertion That Regulates Stability
Molecular Cell, Vol 22, 205-216, 21 April 2006
Abstract
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18 April 2006
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Gwen Ericson
Cancer
therapy based on anatomical location may soon be obsolete
Washington University in St. Louis, Medical News Releases, 18 April 2006
News
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Zhang W, Shannon WD, Duncan J, Scheffer GL, Scheper
RJ, McLeod HL.
Expression
of drug pathway proteins is independent of tumor type
Journal of Pathology, Early View, Published Online: 28 Feb 2006, DOI:
10.1002/path.1955
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17 April 2006
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Bonnie Kourvelas
Technique
could speed new medulloblastoma drugs
EurekAlert!, 17 April 2006
News
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Margaret C. Thompson, Christine Fuller,
Twala L. Hogg, James Dalton, David Finkelstein, Ching C. Lau, Murali
Chintagumpala, Adekunle Adesina, David M. Ashley, Stewart J. Kellie,
Michael D. Taylor, Tom Curran, Amar Gajjar, and Richard J. Gilbertson
Genomics
Identifies Medulloblastoma Subgroups That Are Enriched for Specific
Genetic Alterations
JCO Early Release, published online ahead of print Mar 27 2006 -
10.1200/JCO.2005.04.4974
Abstract
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Gail Gallessich
Scientists
discover a genetic switch that links animal growth and cancer
EurekAlert!, 17 April 2006
News
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Masamitsu Fukuyama,
Ann E. Rougvie, and
Joel
H. Rothman
C.
elegans DAF-18/PTEN Mediates Nutrient-Dependent Arrest of Cell Cycle and Growth in
the Germline
Current Biology, Vol 16, 773-779, 18 April 2006
Abstract
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Reuters Health
Parents
correct on quality of life in young cancer patients
OncoLink, 17 April 2006
News
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Kathryn M. W. Russell, M.S., Melissa
Hudson, M.D., Alanna Long, B.A., Sean Phipps, Ph.D.
Assessment
of health-related quality of life in children with cancer
Cancer, Volume 106, Issue 10, Pages 2267-2274; Published Online: 10 Apr
2006; DOI: 10.1002/cncr.21871
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14 April 2006
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Franklin Hoke
New
mechanism for essential genome-wide gene silencing identified
EurekAlert!, Public release date: 14-Apr-2006
News
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Dafna Nathan, Kristin
Ingvarsdottir, David E. Sterner, Gwendolyn R.
Bylebyl, Milos Dokmanovic, Jean A. Dorsey,
Kelly A. Whelan, Mihajlo Krsmanovic, William
S. Lane, Pamela B. Meluh, Erica S. Johnson
and Shelley L. Berger
Histone
sumoylation is a negative regulator in Saccharomyces cerevisiae and
shows dynamic interplay with positive-acting histone modifications
Genes and Development, Published online before print April 5, 2006, DOI:
10.1101/gad.1404206
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12 April 2006
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Adam Cohen
Rewind,
please: OMRF scientist reverses process of cell division
Oklahoma Medical Research Foundation, News Releases, 12 April 2006
News
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Tamara A. Potapova, John R. Daum,
Bradley D. Pittman, Joanna R. Hudson, Tara N. Jones, David L. Satinover,
P. Todd Stukenberg and Gary J. Gorbsky
The reversibility of
mitotic exit in vertebrate cells
Nature, 440, 954-958 (13 April 2006)
Abstract
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Sarah L. White, Ph.D.
Diabetes
and Cancer: Alpha Connection
Ludwig Institute for Cancer Research, News, 12 April 2006
News
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Lazaros C. Foukas, Marc Claret, Wayne
Pearce, Klaus Okkenhaug, Stephen Meek, Emma Peskett, Sara Sancho, Andrew
J. H. Smith, Dominic J. Withers and Bart Vanhaesebroeck
Critical
role for the p110α phosphoinositide-3-OH kinase in growth and
metabolic regulation
Nature, Advance online publication 12 April 2006,
DOI:10.1038/nature04694
Abstract
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11 April 2006
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Reuters Health
Targeted
nanoparticle therapy shows promise against cancer, in mice
OncoLink, 11 April 2006
News
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Omid C. Farokhzad, Jianjun
Cheng, Benjamin A. Teply, Ines Sherifi, Sangyong
Jon, Philip W. Kantoff, Jerome P. Richie,
and Robert Langer
Targeted
nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
PNAS, April 18, 2006, vol.103, no.16, 6315-6320; Published online
before print April 10, 2006; DOI: 10.1073/pnas.0601755103
Abstract
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10 April 2006
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Growth
Factor-promoting Angiogenesis Expressed In Tumor Cells And Normal Neurons
Science Daily, April 10, 2006
News
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Lixin Sun,
Ai-Min Hui, Qin Su,
Alexander Vortmeyer, Yuri Kotliarov,
Sandra Pastorino, Antonino Passaniti,
Jayant Menon, Jennifer Walling,
Rolando Bailey, Marc Rosenblum,
Tom Mikkelsen, and
Howard
A. Fine
Neuronal
and glioma-derived stem cell factor induces angiogenesis within the brain
Cancer Cell, Vol 9, 287-300, April 2006
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9 April 2006
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Warren Froelich
Inflammation
And Drugs To Control This Activity Studied In A Variety Of Tumors Sites
Antihistamine and Anti-inflammatory Drug Use Associated Differently for
High-Grade Versus Low-Grade Gliomas
Medical News Today, 9 April 2006
News
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Michael E. Scheurer, Margaret Wrensch, Randa
A. El-Zein, Michelle Moghadassi, Rei Miike, Kenneth D. Aldape, Melissa L.
Bondy
Antihistamine
and anti-inflammatory drug use associated differently for high-grade
versus low-grade gliomas
Proc Amer Assoc Cancer Res 2006;47:846.
Meeting
Abstract |
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Dr Stephanie Williams
Legume
compunds may help cancer treatment
The University of Queensland, Research Australia, 9 April 2006
News
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7 April 2006
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Carmen Phillips
Study
Affirms New Therapeutic Target for Malignant Gliomas
NCI Cancer Bulletin, April 11, 2006 • Volume 3 / Number 15
News
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Warren Froelich
Cancerous
vs. healthy cells: Researchers identify the road to success.
Studies determine best route for targeted therapies
EurekAlert!, Public release date: 7-Apr-2006
News
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Ai-Min Hui, LiXin Sun, Yuri
Kotliarov, Jean C. Zenklusen, Howard A. Fine
NF-κB
as a therapeutic target in malignant gliomas
Proc Amer Assoc Cancer Res 2006;47:1506
Meeting
Abstract |
News
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Reuters Health
Donepezil
improves cognition in brain tumor patients
OncoLink, 7 April 2006
News
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Edward G. Shaw, Robin
Rosdhal, Ralph B. D'Agostino, Jr, James Lovato,
Michelle J. Naughton, Michael E. Robbins, Stephen
R. Rapp
Phase II Study
of Donepezil in Irradiated Brain Tumor Patients: Effect on Cognitive
Function, Mood, and Quality of Life
Journal of Clinical Oncology, Vol 24, No 9 (March 20), 2006: pp.
1415-1420; DOI: 10.1200/JCO.2005.03.3001
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News
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6 April 2006
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Keith McKeown
Enzyme crystal structure reveals 'unexpected' genome repair functions
EurekAlert!, Public release date: 6-Apr-2006
News
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Li Fan,
Andrew S. Arvai, Priscilla
K. Cooper, Shigenori Iwai,
Fumio Hanaoka, and
John
A. Tainer
Conserved
XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway
Selection of Transcription or Excision Repair
Molecular Cell, Vol 22, 27-37, 7 April 2006
Abstract
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News
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Will Boggs, MD
Alternate
erythropoietin dosing effective in anemic cancer patients
OncoLink, 6 April 2006
News
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David P. Steensma, Roy
Molina, Jeff A. Sloan, Daniel A. Nikcevich,
Paul L. Schaefer, Kendrith M. Rowland, Jr, Todor
Dentchev, Paul J. Novotny, Loren K. Tschetter,
Steven R. Alberts, Thomas F. Hogan, Amy
Law, Charles L. Loprinzi
Phase III
Study of Two Different Dosing Schedules of Erythropoietin in Anemic
Patients With Cancer
Journal of Clinical Oncology, Vol 24, No 7 (March 1), 2006: pp. 1079-1089;
DOI: 10.1200/JCO.2005.02.7276
Abstract |
Full
Text |
Reprint
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News
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Benny Chung-Ying Zee
Planned
Equivalence or Noninferiority Trials Versus Unplanned Noninferiority
Claims: Are They Equal
Journal of Clinical Oncology, Vol 24, No 7 (March 1), 2006: pp. 1026-1028;
DOI: 10.1200/JCO.2005.04.9684
Full Text |
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5 April 2006
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Harry
Schrickx
OMS to
participate in an international clinical trial to optimize brain tumor
therapy
OncoMethylome
Sciences, Press Releases, 5 April 2006
News
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Monika E. Hegi, Ph.D.,
Annie-Claire Diserens, M.Sc., Thierry Gorlia, M.Sc., Marie-France Hamou,
Nicolas de Tribolet, M.D., Michael Weller, M.D., Johan M. Kros, M.D.,
Johannes A. Hainfellner, M.D., Warren Mason, M.D., Luigi Mariani, M.D.,
Jacoline E.C. Bromberg, M.D., Peter Hau, M.D., René O. Mirimanoff, M.D.,
J. Gregory Cairncross, M.D., Robert C. Janzer, M.D., and Roger Stupp, M.D.
MGMT
Gene Silencing and Benefit from Temozolomide in Glioblastoma
The New England Journal of Medicine,
Volume 352:997-1003, Number 10, March 10, 2005
Abstract
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4 April 2006
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Christine Guilfoy
Equivalent
of 2-4 drinks daily fuels blood vessel growth, encourages cancer tumors in
mice
EurekAlert!, Public release date: 4-Apr-2006
News
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1 April 2006
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Christian Nordqvist
Extensive
Cell Phone Use Linked To Brain Tumors, Swedish Study
Medical
News Today, 1 April 2006
News
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Lennart Hardell, Michael Carlberg and
Kjell Hansson Mild
Pooled
analysis of two case–control studies on use of cellular and cordless
telephones and the risk for malignant brain tumours diagnosed in 1997–2003
International Archives of Occupational and Environmental Health,
Online First, Published online: 16 March 2006
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Published
in April
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Options for Treatment of
Glioblastoma
Neurosurgical Focus, April 2006, Volume 20, Issue 4
Contents
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Nature Reviews / Cancer
Research Highlights, Volume 6, No.4, April 2006
News
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Martin Benesch, Herwig Lackner,
Petra Sovinz, Elisabeth Suppan, Wolfgang Schwinger, Hans-Georg Eder,
Hans Jürgen Dornbusch, Andrea Moser, Karin Triebl-Roth
and Christian Urban
Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between
1983 and 2003
Journal of Neuro-Oncology, Published online: 25 April 2006; DOI: 10.1007/s11060-005-9091-z
Abstract
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Patrizia Tunici, Ph.D., Dwain Irvin,
Ph.D., M.P.H., Gentao Liu, Ph.D., Xiangpeng Yuan, Ph.D., Zeng Zhaohui,
Ph.D., Hiushan Ng, M.S., and John S. Yu, M.D.
Brain tumor stem cells: new
targets for clinical treatments?
Neurosurg Focus 20 (4):E27, April 2006
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Gentao Liu, Keith L
Black and John S Yu
Sensitization of malignant glioma to
chemotherapy through dendritic cell vaccination
Expert Review of Vaccines, Apr 2006, Vol. 5, No. 2, Pages 233-247
Abstract
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