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Volume 5, Supplement 4 - 30 April 2006



27 April 2006

Edward R. Winstead
Brain Cancer Study Supports Fluorescence-Guided Surgery
NCI Cancer Bulletin, May 9, 2006, Volume 3, Number 19
News

Reuters Health
Fluorescence-guided surgery improves glioma survival
OncoLink, 27 April 2006
News

Walter Stummer, Uwe Pichlmeier, Thomas Meinel, Otmar Dieter Wiestler, Friedhelm Zanella and Hans-Jürgen Reulen, for the ALA-Glioma Study Group
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
The Lancet Oncology, Volume 7, Number 5, May 2006, pp 392-401; DOI:10.1016/S1470-2045(06)70665-9
Abstract |
News News

(American Association of Neurological Surgeons annual meeting)
Reuters Health
Language mapping aids in speech preservation with glioma resection
OncoLink, 27 April 2006
News

Eileen Scahill
Arthritis drug might reduce fatigue in cancer patients
Ohio State University, Research News, 24 April 2006
News

J. Paul Monk, Gary Phillips, Ross Waite, John Kuhn, Larry J. Schaaf, Gregory A. Otterson, Denis Guttridge, Chris Rhoades, Manisha Shah, Tamara Criswell, Michael A. Caligiuri, Miguel A. Villalona-Calero
Assessment of Tumor Necrosis Factor Alpha Blockade As an Intervention to Improve Tolerability of Dose-Intensive Chemotherapy in Cancer Patients
Journal of Clinical Oncology, Vol 24, No 12 (April 20), 2006: pp. 1852-1859 - DOI: 10.1200/JCO.2005.04.2838
Abstract | News

Megan Rauscher
Timed meals and chemo may boost anti-cancer therapy
OncoLink, 27 April 2006
News

Alec J. Davidson, Martin Straume, Gene D. Block, Michael Menaker
Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver
Int Journal of Cancer, Volume 118, Issue 7, Pages 1623 – 1627 (1 April 2006); Published Online: 17 Oct 2005; DOI: 10.1002/ijc.21591
Abstract |

26 April 2006

Jennifer Michalowski
Better model of deadly brain cancer
EurekAlert!, 26 April 2006
News

Catherine T. Yan, Dhruv Kaushal, Michael Murphy, Yu Zhang, Abhishek Datta, Changzhong Chen, Brianna Monroe, Gustavo Mostoslavsky, Kristen Coakley, Yijie Gao, Kevin D. Mills, Alex P. Fazeli, Suprawee Tepsuporn, Giles Hall, Richard Mulligan, Edward Fox, Roderick Bronson, Umberto De Girolami, Charles Lee, and Frederick W. Alt
XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice
Proc. Natl. Acad. Sci. USA,
Published online before print May 2, 2006; 10.1073/pnas.0601938103
Abstract | News

Amy Adams
Stanford scientists identify protein involved in fast-spreading cancers
EurekAlert!, 26 April 2006
News

Janine T. Erler, Kevin L. Bennewith, Monica Nicolau, Nadja Dornhöfer, Christina Kong, Quynh-Thu Le, Jen-Tsan Ashley Chi, Stefanie S. Jeffrey and Amato J. Giaccia
Lysyl oxidase is essential for hypoxia-induced metastasis
Nature, 440, 1222-1226 (27 April 2006); doi:10.1038/nature04695
Abstract |
News


25 April 2006

Laura Sussman
Study finds novel vaccine curbs brain tumor growth, increases survival
EurekAlert!, 25 April 2006
News


24 April 2006

Elizabeth McCrocklin
Weizmann Institute Scientists Create a Method for Predicting Chemotherapy Success That Indicates how Easily the Drug can be Delivered Into the Tumor
Weizmann Institute, News Releases, 24 April 2006
News

Yaron Hassid, Edna Furman-Haran, Raanan Margalit, Raya Eilam and Hadassa Degani
Noninvasive Magnetic Resonance Imaging of Transport and Interstitial Fluid Pressure in Ectopic Human Lung Tumors
Cancer Research, 66, 4159-4166, April 15, 2006
Abstract |
News

Thomas Rosol
Nanotechnology may find disease before it starts
Ohio State University, Research News, 24 April 2006
News

Jun Liu, Andrea L Levine, John S Mattoon, Mamoru Yamaguchi, Robert J Lee, Xueliang Pan and Thomas J Rosol
Nanoparticles as image enhancing agents for ultrasonography
Phys. Med. Biol., 2006 May 7;51(9):2179-89; Epub 2006 Apr 10; doi:10.1088/0031-9155/51/9/004
Abstract |
News

Paul Preuss
Revealing the Secrets of WRN. The Unique Protein Responsible for Werner's Syndrome Aids Research in Cancer and Aging
Berkeley Lab Research News, 24 April 2006
News

J Jefferson P Perry, Steven M Yannone, Lauren G Holden, Chiharu Hitomi, Aroumougame Asaithamby, Seungil Han, Priscilla K Cooper, David J Chen & John A Tainer
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing
Nature Structural & Molecular Biology, Published online: 23 April 2006; doi:10.1038/nsmb1088
Abstract |
News


23 April 2006

Dr Branwen Morgan
Cancer cells suppress large regions of DNA by a reversible process that can be tackled
EurekAlert!, 23 April 2006
News

Jordi Frigola, Jenny Song, Clare Stirzaker, Rebecca A Hinshelwood, Miguel A Peinado & Susan J Clark
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
Nature Genetics, 38, 540 - 549 (2006), Published online: 23 April 2006; doi:10.1038/ng1781
Abstract |
News


20 April 2006

Darrell E. Ward
Viral protein helps infected T cells stick to uninfected cells
The Ohio State University, Research News, 20 April 2006
News

Seung-jae Kim, Amrithraj M. Nair, Soledad Fernandez, Lawrence Mathes and Michael D. Lairmore
Enhancement of LFA-1-Mediated T Cell Adhesion by Human T Lymphotropic Virus Type 1 p12I
The Journal of Immunology, 2006, 176: 5463-5470, 1 May 2006
Abstract |
News

Brad Allan
Discovery points to more effective ways of regulating cell signalling
The Walter And Eliza Hall Institute Of Medical Research, Media Release, 20 April 2006
News

Jeffrey J. Babon, Edward J. McManus, Shenggen Yao, David P. DeSouza, Lisa A. Mielke, Naomi S. Sprigg, Tracy A. Willson, Douglas J. Hilton, Nicos A. Nicola, Manuel Baca, Sandra E. Nicholson, and Raymond S. Norton
The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability
Molecular Cell, Vol 22, 205-216, 21 April 2006
Abstract |
News


18 April 2006

Gwen Ericson
Cancer therapy based on anatomical location may soon be obsolete
Washington University in St. Louis, Medical News Releases, 18 April 2006
News

Zhang W, Shannon WD, Duncan J, Scheffer GL, Scheper RJ, McLeod HL. 
Expression of drug pathway proteins is independent of tumor type
Journal of Pathology, Early View, Published Online: 28 Feb 2006, DOI: 10.1002/path.1955
Abstract | News


17 April 2006

Bonnie Kourvelas
Technique could speed new medulloblastoma drugs
EurekAlert!, 17 April 2006
News

Margaret C. Thompson, Christine Fuller, Twala L. Hogg, James Dalton, David Finkelstein, Ching C. Lau, Murali Chintagumpala, Adekunle Adesina, David M. Ashley, Stewart J. Kellie, Michael D. Taylor, Tom Curran, Amar Gajjar, and Richard J. Gilbertson
Genomics Identifies Medulloblastoma Subgroups That Are Enriched for Specific Genetic Alterations
JCO Early Release, published online ahead of print Mar 27 2006 - 10.1200/JCO.2005.04.4974
Abstract |
News

Gail Gallessich
Scientists discover a genetic switch that links animal growth and cancer
EurekAlert!, 17 April 2006
News

Masamitsu Fukuyama, Ann E. Rougvie, and Joel H. Rothman
C. elegans DAF-18/PTEN Mediates Nutrient-Dependent Arrest of Cell Cycle and Growth in the Germline
Current Biology, Vol 16, 773-779, 18 April 2006
Abstract |
News

Reuters Health
Parents correct on quality of life in young cancer patients
OncoLink, 17 April 2006
News

Kathryn M. W. Russell, M.S., Melissa Hudson, M.D., Alanna Long, B.A., Sean Phipps, Ph.D.
Assessment of health-related quality of life in children with cancer
Cancer, Volume 106, Issue 10, Pages 2267-2274; Published Online: 10 Apr 2006; DOI: 10.1002/cncr.21871 
Abstract |
News


14 April 2006

Franklin Hoke
New mechanism for essential genome-wide gene silencing identified
EurekAlert!, Public release date: 14-Apr-2006
News

Dafna Nathan, Kristin Ingvarsdottir, David E. Sterner, Gwendolyn R. Bylebyl, Milos Dokmanovic, Jean A. Dorsey, Kelly A. Whelan, Mihajlo Krsmanovic, William S. Lane, Pamela B. Meluh, Erica S. Johnson and Shelley L. Berger
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
Genes and Development, Published online before print April 5, 2006, DOI: 10.1101/gad.1404206
Abstract | News


12 April 2006

Adam Cohen
Rewind, please: OMRF scientist reverses process of cell division
Oklahoma Medical Research Foundation, News Releases, 12 April 2006
News

Tamara A. Potapova, John R. Daum, Bradley D. Pittman, Joanna R. Hudson, Tara N. Jones, David L. Satinover, P. Todd Stukenberg and Gary J. Gorbsky
The reversibility of mitotic exit in vertebrate cells
Nature, 440, 954-958 (13 April 2006)
Abstract |
News

Sarah L. White, Ph.D.
Diabetes and Cancer: Alpha Connection
Ludwig Institute for Cancer Research, News, 12 April 2006
News

Lazaros C. Foukas, Marc Claret, Wayne Pearce, Klaus Okkenhaug, Stephen Meek, Emma Peskett, Sara Sancho, Andrew J. H. Smith, Dominic J. Withers and Bart Vanhaesebroeck
Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation
Nature, Advance online publication 12 April 2006, DOI:10.1038/nature04694
Abstract | News


11 April 2006

Reuters Health
Targeted nanoparticle therapy shows promise against cancer, in mice
OncoLink, 11 April 2006
News

Omid C. Farokhzad, Jianjun Cheng, Benjamin A. Teply, Ines Sherifi, Sangyong Jon, Philip W. Kantoff, Jerome P. Richie, and Robert Langer
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
PNAS, April 18, 2006, vol.103, no.16, 6315-6320; Published online before print April 10, 2006; DOI: 10.1073/pnas.0601755103
Abstract |
News


10 April 2006

Growth Factor-promoting Angiogenesis Expressed In Tumor Cells And Normal Neurons
Science Daily, April 10, 2006
News

Lixin Sun, Ai-Min Hui, Qin Su, Alexander Vortmeyer, Yuri Kotliarov, Sandra Pastorino, Antonino Passaniti, Jayant Menon, Jennifer Walling, Rolando Bailey, Marc Rosenblum, Tom Mikkelsen, and Howard A. Fine
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
Cancer Cell, Vol 9, 287-300, April 2006

Abstract |
News


9 April 2006

Warren Froelich
Inflammation And Drugs To Control This Activity Studied In A Variety Of Tumors Sites
Antihistamine and Anti-inflammatory Drug Use Associated Differently for High-Grade Versus Low-Grade Gliomas
Medical News Today, 9 April 2006
News

Michael E. Scheurer, Margaret Wrensch, Randa A. El-Zein, Michelle Moghadassi, Rei Miike, Kenneth D. Aldape, Melissa L. Bondy
Antihistamine and anti-inflammatory drug use associated differently for high-grade versus low-grade gliomas
Proc Amer Assoc Cancer Res 2006;47:846.
Meeting Abstract | News

Dr Stephanie Williams
Legume compunds may help cancer treatment
The University of Queensland, Research Australia, 9 April 2006
News


7 April 2006

Carmen Phillips
Study Affirms New Therapeutic Target for Malignant Gliomas
NCI Cancer Bulletin, April 11, 2006 • Volume 3 / Number 15
News

Warren Froelich
Cancerous vs. healthy cells: Researchers identify the road to success.
Studies determine best route for targeted therapies

EurekAlert!, Public release date: 7-Apr-2006
News

Ai-Min Hui, LiXin Sun, Yuri Kotliarov, Jean C. Zenklusen, Howard A. Fine
NF-κB as a therapeutic target in malignant gliomas
Proc Amer Assoc Cancer Res 2006;47:1506

Meeting Abstract | News
Reuters Health
Donepezil improves cognition in brain tumor patients
OncoLink, 7 April 2006
News

Edward G. Shaw, Robin Rosdhal, Ralph B. D'Agostino, Jr, James Lovato, Michelle J. Naughton, Michael E. Robbins, Stephen R. Rapp
Phase II Study of Donepezil in Irradiated Brain Tumor Patients: Effect on Cognitive Function, Mood, and Quality of Life
Journal of Clinical Oncology, Vol 24, No 9 (March 20), 2006: pp. 1415-1420; DOI: 10.1200/JCO.2005.03.3001
Abstract |
News


6 April 2006

Keith McKeown
Enzyme crystal structure reveals 'unexpected' genome repair functions
EurekAlert!, Public release date: 6-Apr-2006
News


Li Fan, Andrew S. Arvai, Priscilla K. Cooper, Shigenori Iwai, Fumio Hanaoka, and John A. Tainer
Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair

Molecular Cell, Vol 22, 27-37, 7 April 2006
Abstract |
News

Will Boggs, MD
Alternate erythropoietin dosing effective in anemic cancer patients
OncoLink, 6 April 2006
News

David P. Steensma, Roy Molina, Jeff A. Sloan, Daniel A. Nikcevich, Paul L. Schaefer, Kendrith M. Rowland, Jr, Todor Dentchev, Paul J. Novotny, Loren K. Tschetter, Steven R. Alberts, Thomas F. Hogan, Amy Law, Charles L. Loprinzi
Phase III Study of Two Different Dosing Schedules of Erythropoietin in Anemic Patients With Cancer
Journal of Clinical Oncology, Vol 24, No 7 (March 1), 2006: pp. 1079-1089; DOI: 10.1200/JCO.2005.02.7276
Abstract | Full Text | Reprint |
News

Benny Chung-Ying Zee
Planned Equivalence or Noninferiority Trials Versus Unplanned Noninferiority Claims: Are They Equal
Journal of Clinical Oncology, Vol 24, No 7 (March 1), 2006: pp. 1026-1028; DOI: 10.1200/JCO.2005.04.9684
Full Text | Reprint


5 April 2006

Harry Schrickx
OMS to participate in an international clinical trial to optimize brain tumor therapy

OncoMethylome Sciences, Press Releases, 5 April 2006
News

Monika E. Hegi, Ph.D., Annie-Claire Diserens, M.Sc., Thierry Gorlia, M.Sc., Marie-France Hamou, Nicolas de Tribolet, M.D., Michael Weller, M.D., Johan M. Kros, M.D., Johannes A. Hainfellner, M.D., Warren Mason, M.D., Luigi Mariani, M.D., Jacoline E.C. Bromberg, M.D., Peter Hau, M.D., René O. Mirimanoff, M.D., J. Gregory Cairncross, M.D., Robert C. Janzer, M.D., and Roger Stupp, M.D.
MGMT
Gene Silencing and Benefit from Temozolomide in Glioblastoma
The New England Journal of Medicine, Volume 352:997-1003, Number 10, March 10, 2005
Abstract | BrainLife | Full Text | Reprint |
News


4 April 2006

Christine Guilfoy
Equivalent of 2-4 drinks daily fuels blood vessel growth, encourages cancer tumors in mice
EurekAlert!, Public release date: 4-Apr-2006
News


1 April 2006

Christian Nordqvist
Extensive Cell Phone Use Linked To Brain Tumors, Swedish Study
Medical News Today, 1 April 2006
News

Lennart Hardell, Michael Carlberg and Kjell Hansson Mild
Pooled analysis of two case–control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997–2003
International Archives of Occupational and Environmental Health, Online First, Published online: 16 March 2006
Abstract | News


Published in April

Options for Treatment of Glioblastoma
Neurosurgical Focus, April 2006, Volume 20, Issue 4

Contents

Nature Reviews / Cancer
Research Highlights, Volume 6, No.4, April 2006
News

Martin Benesch, Herwig Lackner, Petra Sovinz, Elisabeth Suppan, Wolfgang Schwinger, Hans-Georg Eder, Hans Jürgen Dornbusch, Andrea Moser, Karin Triebl-Roth and Christian Urban
Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between 1983 and 2003
Journal of Neuro-Oncology, Published online: 25 April 2006; DOI: 10.1007/s11060-005-9091-z
Abstract

Patrizia Tunici, Ph.D., Dwain Irvin, Ph.D., M.P.H., Gentao Liu, Ph.D., Xiangpeng Yuan, Ph.D., Zeng Zhaohui, Ph.D., Hiushan Ng, M.S., and John S. Yu, M.D.
Brain tumor stem cells: new targets for clinical treatments?
Neurosurg Focus 20 (4):E27, April 2006

Gentao Liu, Keith L Black and John S Yu
Sensitization of malignant glioma to chemotherapy through dendritic cell vaccination
Expert Review of Vaccines, Apr 2006, Vol. 5, No. 2, Pages 233-247
Abstract

 

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