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Electric Fields
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Basic Science


Cho MR, Thatte HS, Lee RC, Golan DE.
Reorganization of microfilament structure induced by ac electric fields.
FASEB J. 1996 Nov;10(13):1552-8.
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Cucullo L, Dini G, Hallene KL, Fazio V, Ilkanich EV, Igboechi C, Kight KM, Agarwal MK, Garrity-Moses M, Janigro D.
Very low intensity alternating current decreases cell proliferation.
Glia. 2005 Jul;51(1):65-72. Epub 2005 Mar 18.
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Giladi M, Porat Y, Blatt A, Shmueli E, Wasserman Y, Kirson ED, Palti Y.
Microbial growth inhibition by alternating electric fields in mice with Pseudomonas aeruginosa lung infection.
Antimicrob Agents Chemother. 2010 Aug;54(8):3212-8. Epub 2010 Jun 14.
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Giladi M, Porat Y, Blatt A, Wasserman Y, Kirson ED, Dekel E, Palti Y
Microbial growth inhibition by alternating electric fields.
Antimicrob Agents Chemother. 2008 Oct;52(10):3517-22. Epub 2008 Jul 28.
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Pawłowski P, Szutowicz I, Marszałek P, Fikus M.
Bioelectrorheological model of the cell. 5. Electrodestruction of cellular membrane in alternating electric field.
Biophys J. 1993 Jul;65(1):541-9.
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Rosa S. Schneiderman, Eilon D. Kirson, Josef Vymazal, Tomas Vlasek, Zdenka Burianova, Aviran Itzhaki, Daniel Mordechovich, Zoya Gurvich, Esther Shmueli, Bernhard Ryffel, Dorit Goldsher, Yoram Wasserman, Yoram Palti
Synergism between chemotherapy and alternating electric fields (TTFields) in cancer cell proliferation inhibition and solid tumor treatment
2008 AACR Annual Meeting, April 12-16, 2008, San Diego, CA, Abstract Number: 1007; Apr 13, 2008
  Abstract |   News


Glioblastoma


Kirson ED, Schneiderman RS, Dbalę V, Tovarys F, Vymazal J, Itzhaki A, Mordechovich D, Gurvich Z, Shmueli E, Goldsher D, Wasserman Y, Palti Y.
Chemotherapeutic treatment efficacy and sensitivity are increased by adjuvant alternating electric fields (TTFields).
BMC Med Phys. 2009 Jan 8;9:1.
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Kirson ED, Dbalę V, Tovarys F, Vymazal J, Soustiel JF, Itzhaki A, Mordechovich D, Steinberg-Shapira S, Gurvich Z, Schneiderman R, Wasserman Y, Salzberg M, Ryffel B, Goldsher D, Dekel E, Palti Y.
Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors.
Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10152-7. Epub 2007 Jun 5.
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Kirson ED, Gurvich Z, Schneiderman R, Dekel E, Itzhaki A, Wasserman Y, Schatzberger R, Palti Y.
Disruption of cancer cell replication by alternating electric fields.
Cancer Res. 2004 May 1;64(9):3288-95
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Liu HL, Hua MY, Chen PY, Chu PC, Pan CH, Yang HW, Huang CY, Wang JJ, Yen TC, Wei KC.
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment.
Radiology. 2010 May;255(2):415-25.
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Peruzzi P, Chiocca EA.
Treating Glioblastoma Multiforme With Electrical Fields.
World Neurosurg. 2010 Aug;74(2-3):208-211.
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Recurrent Glioblastoma


Ram, Gutin PH and Stupp R on behalf of the EF-11 study investigators.
Subgroup and quality of life analyses of the phase III clinical trial of NovoTTF-100A versus best standard chemotherapy for recurrent glioblastoma.
Abstracts from the 15th Annual Meeting of the Society for Neuro-Oncology (SNO), November 18–21, 2010, Montreal, Quebec, Canada
Neuro Oncol (2010) 12 (suppl 4): iv36-iv57.
November 2010. Abstract no.
NO-55. 
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Stupp R, Kanner A, Engelhard H, Heidecke V, Taillibert S, Lieberman FS, Dbalę V, Kirson ED, Palti Y, Gutin PH.
A prospective, randomized, open-label, phase III clinical trial of NovoTTF-100A versus best standard of care chemotherapy in patients with recurrent glioblastoma.
J Clin Oncol (Meeting Abstracts) 2010 28: LBA2007. June 20, 2010
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Pless M, Weinberg U.
Tumor treating fields: concept, evidence and future.
Expert Opin Investig Drugs. 2011 May 9;. [Epub ahead of print]
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Gliomas


Agerholm-Larsen B, Iversen HK, Ibsen P, Moller JM, Mahmood F, Jensen KS, Gehl J.
Preclinical validation of electrochemotherapy as an effective treatment for brain tumors.
Cancer Res. 2011 Apr 20. [Epub ahead of print]
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