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Notch and Hedgehog Targeting

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Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG.
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Clin Cancer Res. 2010 Dec 15;16(24):6060-70.
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