BRAINLIFE Brain Tumor Medical Database
Glioblastoma / Treatment / Thalidomide

Clinical Investigations 1

Home > Database > Glioblastoma > Treatment > Thalidomide > Clinical Investigations 1

Contents



Glioblastoma


Baumann F, Bjeljac M, Kollias SS, Baumert BG, Brandner S, Rousson V, Yonekawa Y, Bernays RL.
Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme.
J Neurooncol. 2004 Mar-Apr;67(1-2):191-200.
  Abstract |   Reprint |   Related articles

M. Bjeljac, F. Baumann and R. Bernays
Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 451

J. N. Capparella, V. M. Johnson, X. Maestri-Moden, P. Sampath, N. Ready, L. Alderson
Phase II trial of daily oral temozolomide and thalidomide in newly diagnosed glioblastoma multiforme before radiation therapy
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 483

Chang SM, Lamborn KR, Malec M, Larson D, Wara W, Sneed P, Rabbitt J, Page M, Nicholas MK, Prados MD.
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme.
Int J Radiat Oncol Biol Phys. 2004 Oct 1;60(2):353-7.
  Abstract |   Related articles

Drappatz J, Wong ET, Schiff D, Kesari S, Batchelor TT, Doherty L, Lafrankie DC, Ramakrishna N, Weiss S, Smith ST, Ciampa A, Zimmerman J, Ostrowsky L, David K, Norden A, Barron L, Sceppa C, Black PM, Wen PY.
A Pilot Safety Study of Lenalidomide and Radiotherapy for Patients with Newly Diagnosed Glioblastoma Multiforme
Int J Radiat Oncol Biol Phys. 2008 May 29. [Epub ahead of print]
 Abstract

Fadul CE, Kingman LS, Meyer LP, Cole BF, Eskey CJ, Rhodes CH, Roberts DW, Newton HB, Pipas JM.
A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme
J Neurooncol. 2008 Jul 26; [Epub ahead of print]
 Abstract

Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J, Kieran M, Wen PY.
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults.
Neuro Oncol. 2008 Jun;10(3):300-8. Epub 2008 Apr 10.
  Abstract |   Reprint |   Related articles

Riva M, Imbesi F, Beghi E, Galli C, Citterio A, Trapani P, Sterzi R, Collice M.
Temozolomide and thalidomide in the treatment of glioblastoma multiforme.
Anticancer Res. 2007 Mar-Apr;27(2):1067-71
  Abstract |   Reprint |   Related articles

Christopher D. Turner, Susan Chi, Karen J. Marcus, Tobey MacDonald, Roger J. Packer, Tina Young Poussaint, Sridhar Vajapeyam, Nicole Ullrich, Liliana C. Goumnerova, R. Michael Scott, Caitlin Briody, Christine Chordas, Mary Ann Zimmerman and Mark W. Kieran
Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme
J Neurooncol. 2006 Sep 22; [Epub ahead of print]
Abstract


Recurrent Tumors


Jo Glass, Gruber Michael , Anit Nirenberg
Phase I/II Study of Carboplatin and Thalidomide in Recurrent Glioblastoma Multiforme

ASCO Proceedings, 1999 Annual Meeting, Abstract
No. 551

Groves MD, Puduvalli VK, Chang SM, Conrad CA, Gilbert MR, Tremont-Lukats IW, Liu TJ, Peterson P, Schiff D, Cloughesy TF, Wen PY, Greenberg H, Abrey LE, DeAngelis LM, Hess KR, Lamborn KR, Prados MD, Yung WK.
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme
J Neurooncol. 2007 Feb;81(3):271-7. Epub 2006 Sep 22.
  Abstract |   Reprint |   Related articles

Marx GM, Pavlakis N, McCowatt S, Boyle FM, Levi JA, Bell DR, Cook R, Biggs M, Little N, Wheeler HR
Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme

J Neurooncol 2001 Aug;54(1):31-8 (Abstract+)

Surasak Phuphanich
Recurrent Multicentric Glioblastoma Multiforme Responds to Thalidomide and Chemotherapy
Oncology, Vol 16, No 3 (March 2002), Letter to the Editor
  Abstract |   Full Text |   Reprint

Puduvalli VK, Giglio P, Groves MD, Hess KR, Gilbert MR, Mahankali S, Jackson EF, Levin VA, Conrad CA, Hsu SH, Colman H, de Groot JF, Ritterhouse MG, Ictech SE, Yung WK
Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme
Neuro Oncol. 2008 Feb 26; [Epub ahead of print]
  Abstract


Gliomas


T. Ahmed, B. Chen, G. Rabbani, M. N. Wallam and D. Benzil
Phase II trial of thalidomide (TD), tamoxifen (TX), and temozolomide (T) for patients with advanced malignant gliomas (MG)
2005 ASCO Annual Meeting. Orlando, FL. May 13-17. Abstract No. 1575
Journal of Clinical Oncology, Vol 23, No 16S (June 1 Supplement), 2005: 1575

A. Desjardins, J. A. Quinn, D. A. Reardon, J. N. Rich, J. J. Vredenburgh, C. Efird, H. S. Friedman
Phase II study of thalidomide and daily cyclophosphamide for adults with malignant glioma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1554

Gao S, Yang XJ, Zhang WG, Ji YW, Pan Q
Mechanism of thalidomide to enhance cytotoxicity of temozolomide in U251-MG glioma cells in vitro
Chin Med J (Engl). 2009 Jun 5;122(11):1260-6
  Abstract |   Full Text |   Reprint

M. Gelati, E. Corsini, S. Frigerio, B. Pollo, G. Broggi, D. Croci, A. Silvani, A. Boiardi, A. Salmaggi
Effects of Thalidomide on Parameters Involved in Angiogenesis: An in vitro Study
Journal of Neuro-Oncology, 64 (3): 193-201, September 2003


Recurrent Tumors


W. Adler, F. C. Lee
A phase I trial using combination irinotecan and thalidomide for recurrent CNS tumors
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 489

Fine HA, Kim L, Albert PS, Duic JP, Ma H, Zhang W, Tohnya T, Figg WD, Royce C
A phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors
Clin Cancer Res. 2007 Dec 1;13(23):7101-6
Abstract

Fine HA, Wen PY, Maher EA, Viscosi E, Batchelor T, Lakhani N, Figg WD, Purow BW, Borkowf CB
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas
J Clin Oncol. 2003 Jun 15;21(12):2299-304

H. A. Fine, L. Kim, C. Royce, J. P. Duic, L. J. Cohen, S. Mitchell
A phase I trial of CC-5103, a potent thalidomide analog, in patients with recurrent high-grade gliomas and other refractory CNS malignancies
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 418

Fine HA, Figg WD, Jaeckle K, Wen PY, Kyritsis AP, Loeffler JS, Levin VA, Black PM, Kaplan R, Pluda JM, Yung WK
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
J Clin Oncol 2000 Feb;18(4):708-15 (PDF Full Text)

HA Fine, JS Loeffler, A Kyritsis, P Wen, PM Black, VA Levin, S Graham, WKA Yung
A phase II trial of the anti-angiogenic agent, thalidomide, in patients with recurrent high-grade gliomas

ASCO Proceedings, 1997 Annual Meeting, Abstract No. 1372

Giglio P, Dhamne M, Hess KR, Gilbert MR, Groves MD, Levin VA, Kang SL, Ictech SE, Liu V, Colman H, Conrad CA, Loghin M, de Groot J, Yung WK, Puduvalli VK.
Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma.
Cancer. 2011 Nov 15;. [Epub ahead of print]
  Abstract |   Related articles

Kesari S, Schiff D, Doherty L, Gigas DC, Batchelor TT, Muzikansky A, O'Neill A, Drappatz J, Chen-Plotkin AS, Ramakrishna N, Weiss SE, Levy B, Bradshaw J, Kracher J, Laforme A, Black PM, Folkman J, Kieran M, Wen PY.
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.
Neuro Oncol. 2007 Jul;9(3):354-63. Epub 2007 Apr 23.
  Abstract |   Reprint |   Related articles

Ruiz J, Case D, Enevold G, Rosdhal R, Tatter SB, Ellis TL, McQuellon RP, McMullen KP, Stieber VW, Shaw EG, Lesser GJ.
A phase II trial of thalidomide and procarbazine in adult patients with recurrent or progressive malignant gliomas.
J Neurooncol. 2011 Aug 26. [Epub ahead of print]
  Abstract |   Related articles

Short SC, Traish D, Dowe A, Hines F, Gore M, Brada M
Thalidomide as an anti-angiogenic agent in relapsed gliomas
J Neurooncol. 2001 Jan;51(1):41-5. (Abstract+)


Pediatric Patients


López-Aguilar E, Sepúlveda-Vildósola AC, Betanzos-Cabrera Y, Rocha-Moreno YG, Gascón-Lastiri G, Rivera-Márquez H, Wanzke-Del-Angel V, Cerecedo-Díaz F, Cruz-Yañez Hde L.
Phase II Study of Metronomic Chemotherapy with Thalidomide, Carboplatin-Vincristine-Fluvastatin in the Treatment of Brain Stem Tumors in Children
Arch Med Res. 2008 Oct;39(7):655-62; Epub 2008 Aug 17
 Abstract

Recurrent Tumors
Warren KE, Goldman S, Pollack IF, Fangusaro J, Schaiquevich P, Stewart CF, Wallace D, Blaney SM, Packer R, Macdonald T, Jakacki R, Boyett JM, Kun LE.

Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018.
J Clin Oncol. 2010 Dec 13. [Epub ahead of print]
  Abstract |
  Related articles


Cancer Research


Belo AV, Barcelos LS, Teixeir MM, Ferreira MA, Andrade SP.
Differential effects of antiangiogenic compounds in neovascularization, leukocyte recruitment, VEGF production, and tumor growth in mice.
Cancer Invest. 2004;22(5):723-9

Chaudhry V, Cornblath DR, Corse A, Freimer M, Simmons-O'Brien E, Vogelsang G
Thalidomide-induced neuropathy
Neurology 2002 Dec 24;59(12):1872-5

Verheul HM, Panigrahy D, Yuan J, D'Amato RJ
Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits
Br J Cancer 1999 Jan;79(1):114-8


This website is certified by Health On the Net Foundation. Click to verify. HOMEARCHIVES OF NEURO-ONCOLOGYCURRENT NEURO-ONCOLOGYGLIOBLASTOMA REPORTS
SERVICES: About BrainLife | Brain Tumor Medical Database | Children's Corner | Dedication | E-mail Alerts | Journals | Privacy Policy | Publications

This site complies with the HONcode standard for trustworthy health information: verify here bottom