From: Subject: Immature Neurons From CNS Stem Cells Proliferate in Response to Platelet-Derived Growth Factor -- Erlandsson et al. 21 (10): 3483 -- Journal of Neuroscience Date: Sun, 20 Jan 2008 15:47:18 +0100 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0241_01C85B7B.BC962280" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198 This is a multi-part message in MIME format. ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.jneurosci.org/cgi/content/full/21/10/3483?ijkey=e83aeb6016e0bfe3b6e4be7c741221c7bf01543b Immature Neurons From CNS Stem Cells Proliferate in = Response to Platelet-Derived Growth Factor -- Erlandsson et al. 21 (10): = 3483 -- Journal of Neuroscience
3D"J.

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE=20 OF CONTENTS
 3D"
3D" QUICK = SEARCH:   [advanced] 3D"
3D"
Author:
 Keyword(s):
Year:  Vol:  Page: 
3D"
3D"
=
This = Article
3D"
3D"Right Abstract=20 3D"Freely
3D"Right Full=20 Text (PDF)
3D"Right Submit an eLetter =
3D"Right Alert=20 me when this article is cited
3D"Right Alert=20 me when eLetters are posted
3D"Right Alert=20 me if a correction is posted
3D"Right Citation Map
3D"
Services
3D"
3D"Right Email=20 this article to a friend
3D"Right Similar=20 articles in this journal
3D"Right Similar=20 articles in ISI Web of Science
3D"Right Similar=20 articles in PubMed
3D"Right Alert me = to new=20 issues of the journal
3D"Right Down= load=20 to citation manager
3D"Right 3D"reprints
3D"
Citing = Articles
3D"
3D"Right Citing=20 Articles via HighWire
3D"Right Citing=20 Articles via ISI Web of Science (33)
3D"Right Citing Articles via Google = Scholar
3D"
Google = Scholar
3D"
3D"Right Articles by Erlandsson, A. =
3D"Right Articles by Forsberg-Nilsson, = K.
3D"Right Search for Related Content =
3D"
PubMed
3D"
3D"Right PubMed=20 Citation
3D"Right Articles by Erlandsson, A. =
3D"Right Articles by Forsberg-Nilsson, = K.

 Previous=20 Article  |  Next=20 Article 

The Journal of Neuroscience, May 15, 2001,=20 21(10):3483-3491

Immature Neurons From CNS Stem Cells Proliferate in Response to=20 Platelet-Derived Growth Factor

Anna = Erlandsson, Maria=20 Enarsson, and Karin Forsberg-Nilsson

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala = University,=20 SE-751 85 Uppsala, Sweden=20


    ABSTRACT
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

Identifying external signals involved in the regulation of neural = stem cell=20 proliferation and differentiation is fundamental to the = understanding=20 of CNS development. In this study we show that = platelet-derived=20 growth factor (PDGF) can act as a mitogen for neural = precursor cells.=20 Multipotent stem cells from developing CNS can be maintained = in a=20 proliferative state under serum-free conditions in the = presence of=20 fibroblast growth factor-2 (FGF2) and induced to = differentiate into=20 neurons, astrocytes, and oligodendrocytes on withdrawal of = the=20 mitogen. PDGF has been suggested to play a role during the=20 differentiation into neurons. We have investigated the effect = of PDGF=20 on cultured stem cells from embryonic rat cortex. The PDGF = -receptor is constantly expressed during = differentiation=20 of neural stem cells but is phosphorylated only after PDGF-AA = treatment. In contrast, the PDGF 3D"beta-receptor=20 is hardly detectable in uncommitted cells, but its expression = increases during differentiation. We show that PDGF = stimulation leads=20 to c-fos induction, 5'-bromo-2'deoxyuridine = incorporation, and=20 an increase in the number of immature cells stained with = antibodies=20 to neuronal markers. Our findings suggest that PDGF acts as a = mitogen=20 in the early phase of stem cell differentiation to expand the = pool of=20 immature neurons.

Key words: PDGF; neural stem cells; differentiation; neurogenesis; = rat;=20 cortex; development

    INTRODUCTION
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

Neurons and glia in the mature CNS originate from precursor cells in = the=20 ventricular zone of the fetal brain and spinal cord (Williams = et al.,=20 1991). = The division=20 of the precursor cells takes place close to the lumen of the=20 neuroepithelium, after which the postmitotic progeny migrate = from the=20 ventricular zone to assume their final positions (Rakic, = 1972, = 1990; = Hatten, 1990). =

Many reports describe the establishment of in vitro culture of = precursor cells from the embryonic rat or mouse brain (for = review,=20 see Gage, 1998; = Temple and=20 Alvarez-Buylla, 1999; = Vescovi=20 and Snyder, 1999).=20 Neuroepithelial stem cells can be expanded in fibroblast = growth=20 factor-2 (FGF2)-containing serum-free medium and induced to=20 differentiate to neurons, astrocytes, or oligodendrocytes by = the=20 withdrawal of mitogen (for review, see McKay, 1997). =

Identification of external signals involved in the regulation of = neural stem=20 cell proliferation and differentiation may allow for improved = transplantation methods and augment the treatment of=20 neurodegenerative disorders. Several investigators report that = in=20 cell cultures of neuroepithelial progenitor cells, exogenously = added=20 growth factors can potentiate survival, induce proliferation, = or=20 facilitate commitment or differentiation into mature phenotypes.=20 Besides the mitogenic effect of FGF2, it is well documented = that=20 ciliary neurotrophic factor (CNTF) acts to direct multipotent = stem cells to an astrocytic fate (Johe et al., 1996; = Bonni et=20 al., 1997; = Rajan and=20 McKay, 1998). = The thyroid=20 hormone, triiodothyronine (T3), has been shown to influence=20 oligodendrocyte differentiation (Johe et al., 1996). = Two previous=20 reports (Johe et al., 1996;=20 Williams et al., 1997) = indicate that=20 PDGF can enhance neuronal differentiation. The possibility = that PDGF=20 acts as a mitogen for immature neurons has been discussed but = not=20 addressed experimentally.

Both PDGF ligands are present within the developing cortex at early = embryonic=20 ages. Hutchins and Jefferson (1992) = detected=20 PDGF-A-positive cells throughout the ventricular zone at = mouse=20 embryonic day (E) 11.5, which is 2 d after neural tube=20 closure and before the differentiation of most glial cells in = all=20 areas of the nervous system. Some PDGF-B-reactive cells can = also=20 be found in the subventricular zone of E14 rat embryos, which = is=20 when rapid cellular proliferation and migration occur = (Sasahara=20 et al., 1992). =

In the present study we aimed at clarifying the effect of PDGF on = cortical=20 neural stem cells in culture. We have found that PDGF-AA = treatment=20 increases 5'-bromo-2'deoxyuridine bromodeoxyuridine (BrdU)=20 incorporation, and as a consequence it increases total cell = number.=20 PDGF-AA was further shown to delay the differentiation of=20 microtubule-associated protein 2 (MAP2)/TuJ1-positive neural=20 precursor cells, possibly by retaining committed but immature = neurons in a proliferative state. Double staining with BrdU=20 antibodies showed that PDGF markedly increased the proportion = of=20 proliferating cells that expressed MAP2. These results = suggest that=20 PDGF acts to expand a pool of immature neurons. =

    MATERIALS AND = METHODS
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

Cell culture. Embryonic cortex was dissected in HBSS (Life=20 Technologies, Paisley, Scotland) from timed-pregnant Sprague Dawley = rats (B&K, Sollentuna, Sweden) on E15 (E1 was defined as the = day=20 of copulatory plug). The tissue was gently triturated, and = meninges=20 and larger cell clumps were allowed to sediment for 10 min,=20 after which the cell suspension was centrifuged. The pellet = was=20 resuspended in N2-medium (Bottenstein and Sato, 1979) = with=20 10 ng/ml FGF2 (Pepro Technologies, London, England) and = plated=20 at a density of 1 =D7 103D-=206 cells per 10 cm tissue culture dish that was = precoated=20 with poly-L-ornithine (Sigma, St. = Louis, MO) and=20 fibronectin (Life Technologies). Fresh FGF2 was added daily, = and the=20 medium was changed every other day. When subconfluent, the = cells were=20 passaged by scraping with a cell lifter (Costar, Cambridge, = MA).=20 After the cells were gently triturated in HBSS, the cell = suspension=20 was centrifuged, and the pellet was resuspended in N2-medium = and=20 plated. The cells were used for experiments 2-6 d after the = first=20 passage. The concentrations of PDGF-AA (Pepro Technologies) = used in=20 the experiments were 10 ng/ml for continuous treatment,=20 20 ng/ml for treatment with a single dose, and = 100 ng/ml=20 for shorter exposures (c-fos and protein kinase B=20 (PKB)/c-Akt experiments).

Immunocytochemistry. Cells were fixed in ice-cold acid ethanol = (90%=20 ethanol, 5% acetic acid). Endogenous peroxidase was quenched = by 0.3%=20 H2O2 in methanol for 20 min followed by = washing with=20 PBS and permeabilization and blocking in 0.1% Triton X-100 = with=20 5% normal goat serum (Dako A/S, Glostrup, Denmark) in PBS for = 30 min. The cells were incubated for 1-4 hr with primary = antibody, washed in PBS, and incubated with biotinylated goat = anti-mouse immunoglobulin (Kirkegaard and Perry Laboratories, = Gaithersburg, MD) for 30 min-1 hr. After washing with = PBS, the=20 reaction was developed with diaminobenzidine (DAB SigmaFast, = Sigma).=20 Incorporation of BrdU was detected using anti-BrdU antibodies = (Amersham Pharmacia Biotech, Uppsala, Sweden). Cells were = pulsed with=20 10 mM BrdU (Amersham Pharmacia = Biotech) for=20 14 hr before fixation. Stained cells were counted, and = the ratio=20 of BrdU-positive cells to total cell number per field at = 200=D7=20 magnification was calculated. Seven parallel fields were = counted for=20 each time point, and each time point was performed in = duplicate. For=20 the double staining of MAP2 and BrdU, a cell proliferation = kit,=20 including a nickel-enhanced peroxidase reaction (Amersham = Pharmacia=20 Biotech), was used for detection of BrdU-positive cells = together with=20 the regular peroxidase reaction for MAP2 as described above.=20 Duplicate cultures were stained for MAP2, and 10 defined = fields=20 of each culture dish were photographed, using a computerized=20 microscope (Axiovert 100TV, Zeiss). = After=20 BrdU staining, the same fields were photographed again. Cells = counts were determined from photographs of stained cells. = Monoclonal=20 anti-MAP2 antibody (clone HM2, Sigma), dilution 1:200, and = monoclonal=20 anti-Tuj1 antibody (BabCO, Nordic Biosite AB, T=E4by, = Sweden),=20 dilution 1:50, were used. A polyclonal antibody to nestin was = a=20 kind gift from Dr. R. McKay (National Institutes of Health,=20 Bethesda, MD).

Deoxynucleotidyl transferase-mediated biotinylated UTP nick end = labeling=20 assay. Cells were grown on poly-L-ornathine = and=20 fibronectin precoated glass coverslips. After fixation in 2%=20 paraformaldehyde, pH 7.4, the cells were stained using a = terminal deoxynucleotidyl transferase-mediated biotinylated = UTP nick=20 end labeling (TUNEL) kit (Roche Diagnostics, Mannheim, = Germany). The=20 proportion of cells going through apoptosis was counted in=20 10 parallel fields, using a fluorescence microscope. = Each time=20 point was performed in duplicate.

Cell counting. Cell counting was performed using a Coulter Z1 = cell=20 counter (Coulter Electronics, Herpendon, UK). The cells were = removed=20 from the dishes by scraping and were then carefully = dissociated and=20 counted. Each experiment was performed in triplicate.

Northern blot analysis. Total RNA was isolated using the = LiCl/urea=20 method (Auffrey and Rougeon, 1980). = For Northern=20 electrophoresis, 12 =B5g of RNA per slot was loaded to a = 1%=20 agarose gel with 2.2 M = formaldehyde. The=20 RNA was transferred to Duralon-UV membranes (Stratagene, La = Jolla,=20 CA) and fixed by baking at 80=B0C under vacuum. 32P-labeled = probes were=20 prepared using a kit for random priming (Megaprime DNA = labeling=20 systems, Amersham Pharmacia Biotech), and hybridization was = performed=20 under high stringency conditions (50% formamide) at 42=B0C = using=20 QuickHyb solution (Stratagene). The intactness and total = amount of=20 RNA were checked by hybridization to a glyceraldehyde = phosphate=20 dehydrogenase (GAPDH) probe. After washing at 55-60=B0C, the = filters=20 were exposed to Phosphor Imager screens (Fuji, Tokyo, Japan) = for=20 12-14 hr and analyzed in a Phosphor Imager (Fuji). = Normalization of=20 PDGF receptor RNA levels was obtained by scanning the = hybridization=20 signal, and the ratio of receptor signal to GAPDH signal was=20 calculated. A cDNA for GAPDH was a gift from Dr. R. Wu = (Cornell=20 University, Ithaca, NY), and murine cDNA for c-fos was = kindly=20 provided by Dr. R. Wallrich (EMBL, Heidelberg, Germany). =

Western blot analysis: total lysate. Cells were lysed = in=20 boiling 2=D7 Laemmli sample buffer (4% SDS, 20% glycerol, Tris-HCl, = pH=20 6.8) and sonicated, and the cell debris was removed by = centrifugation.=20 Protein samples were boiled with 5% betamercaptoethanol and = loaded=20 to the wells of a 8-16% gradient Tris-glycine gel (Novex). = For=20 immunoblotting, the samples were electrically transferred = onto=20 a nitrocellulose membrane (Hybond ECL Nitrocellulose = membrane,=20 Amersham Pharmacia Biotech) according to the protocol = provided=20 by the manufacturer. Nonspecific protein binding to the = filter=20 was blocked by incubation in Tris-buffered saline/Tween = (TBS-T:=20 20 mM Tris base, pH = 7.6, 137 mM NaCl, 0.2% Tween-20) containing 5% BSA for = 1 hr=20 at room temperature, followed by incubation with primary = antibody=20 overnight at 4=B0C. After washing with TBS-T, the membrane = was=20 incubated with peroxidase-conjugated secondary antibody = (Amersham=20 Pharmacia Biotech), dilution 1:5000, for 1 hr at room=20 temperature. After the filter was washed in TBS-T, the blot = was=20 developed using an enhanced chemiluminescence (ECL) system = (Amersham=20 Pharmacia Biotech). Before rehybridization of the filters, = the=20 membrane was dehybridized (20% SDS, Tris-HCl, pH = 6.8, 340 =B5l=20 betamercaptoethanol) at 55=B0C for 30 min and washed in = TBS-T.=20 Primary antibodies were anti-PKB/c-Akt antibody (Akt1 = #06-558,=20 Upstate Biotech) and anti-phosphorylated-PKB/c-Akt antibody=20 (Ser-473-PhosphoAkt #9271S, New England Biolabs), diluted = 1:1000.=20

Western blot analysis: immunoprecipitation. Cell pellets were=20 solubilized in lysis buffer (1% Triton X-100, 20 mM=20 Tris-HCl, pH 7.5, 150 mM = NaCl,=20 2 mM EDTA, 1% aprotinin, 2 mM phenylmethylsulfonyl fluoride, = 250 =B5M orthovanadate) on ice for 5 min, after = which=20 cell debris was removed by centrifugation. = Immunoprecipitation=20 was performed using 150 =B5g protein. Lysates were incubated = with=20 10 =B5l anti-PDGF 3D"alpha-receptor=20 antibody (anti-PDGF-R3D"alpha=20 antibody), R7, for 90 min at 4=B0C and another = 45 min on ice=20 after the addition of 50 =B5l of protein-A-Sepharose = beads=20 (Amersham Pharmacia Biotech). The supernatant was then = incubated with=20 10 =B5l of anti-PDGF 3D"beta-receptor antibody (anti-PDGF-R3D"beta=20 antibody), R33, and new protein-A-Sepharose beads. The R7 and = R33=20 antibodies were kind gifts from Dr. C.-H. Heldin (Ludwig = Institute=20 for Cancer Research, Uppsala, Sweden). The = protein-A-Sepharose was=20 washed three times with lysis buffer and once with ice-cold = PBS. To=20 eluate the protein, the samples were incubated with = 25 =B5l of=20 SDS-sample buffer (Novex, San Diego, CA) with 2% = betamercaptoethanol=20 at 95=B0C for 5 min. The supernatant was loaded to the = wells of a=20 4-12% gradient Tris-glycine gel (Novex). Immunoblotting was = performed=20 as above but with a different filter (Immobilon transfer = membrane;=20 Millipore, Bedford, MA). Primary antibodies were = anti-phosphotyrosine=20 antibody, PY20 (diluted 1:1250; Transduction Laboratories, = Exeter,=20 UK), anti-PDGF3D"alpha-receptor, R7 (diluted 1:500), or = anti-PDGF-receptor, M20 (diluted 1:500; Santa Cruz = Biotechnology,=20 Santa Cruz, CA).

Statistical analysis. For statistical analysis we used ANOVA = followed=20 by Fisher's multiple comparison. Values presented are the=20 means =B1 SEM.


    RESULTS
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

Expression of PDGF receptors during stem=20 cell differentiation

The cell culture system used in this study has been described in = detail=20 elsewhere (Johe et al., 1996). = Briefly,=20 multipotential neural stem cells can be maintained in the = presence of=20 FGF2 and induced to differentiate on withdrawal of the = mitogen to=20 form neurons, astrocytes, and oligodendrocytes. During the = first=20 few days after FGF2 withdrawal, addition of polypeptide = growth=20 factors, cytokines, or hormones can change the proportion of = cell=20 lineages that are generated. PDGF has been suggested to = augment=20 neuronal differentiation in two studies (Johe et al., 1996; = Williams=20 et al., 1997). = In this study=20 we aimed to define the action of PDGF on neuronal stem cells = isolated=20 from embryonic rat cortex. We have shown previously that = these cells=20 express PDGF 3D"alpha-receptor RNA and can respond to PDGF by = chemotaxis=20 (Forsberg-Nilsson et al., 1998). =

Western blot analysis was used to investigate the expression and=20 phosphorylation of PDGF receptors in cultured neuroepithelial = cells=20 during differentiation (Fig. 1).=20 Proliferating cells were compared with cells differentiating = after=20 withdrawal of FGF2. Cell lysates were prepared from = proliferating=20 stem cells (FGF2) and cortical stem cells at=20 1, 2, 4, and 6 d after FGF2 withdrawal = (Fig. 1,=20 No add.). Each cell lysate was first immunoprecipitated = with=20 antibodies to PDGF 3D"alpha-receptor=20 (R7), after which the supernatant was subjected to a second = round of=20 immunoprecipitation with anti-PDGF 3D"beta-receptor=20 antibodies (R33). The membranes were then hybridized with = antibodies=20 to the PDGF 3D"alpha-receptor=20 or the PDGF 3D"beta-receptor. Anti-phosphotyrosine antibody was = used to=20 detect phosphorylation of the receptors. Figure 1=20 shows that although the PDGF 3D"alpha-receptor is expressed on cortical stem cells, = no=20 phosphorylation occurred in the absence of exogenous ligand.=20 Proliferating stem cells treated with 20 ng/ml of = PDGF-AA were=20 used as a positive control for phosphorylated 3D"alpha-receptor.



View = larger=20 version (27K):
[in=20 this window]
[in a new window]
  		Figure 1. =   Western=20 blot analysis was used to study PDGF receptor expression and = phosphorylation in CNS stem cells during differentiation.=20 Proliferating cells (FGF2) were compared with = differentiating=20 cells after FGF2 withdrawal (No add.). All cell = lysates were=20 immunoprecipitated with a PDGF 3D"alpha-receptor antibody. For immunoprecipitation = of the PDGF=20 3D"beta-receptor, the supernatant from the 3D"alpha-receptor precipitation was further incubated = with a=20 PDGF 3D"beta-receptor antibody. Anti-PDGF 3D"alpha-receptor antibody, anti-PDGF 3D"beta-receptor antibody, or anti-phosphotyrosine = antibody=20 was used for immunoblotting. Lysates were made from cortical = stem=20 cells grown in the presence of FGF2, at the start of the = experiment,=20 and from cells grown 1, 2, 4, and 6 d = after FGF2=20 withdrawal. Cells treated with PDGF-AA for 24 hr were = included=20 as a positive control for phosphorylated PDGF 3D"alpha-receptor.

PDGF 3D"beta-receptor=20 expression in cortical stem cells was hardly detectable in uncommitted = cells but=20 increased as the cells differentiated after FGF2 withdrawal. = The=20 phosphorylation of the 3D"beta-receptor=20 followed the same pattern, with no or very little = phosphorylation the=20 first 2 d of differentiation and a distinct = phosphorylation at=20 day 4 that increased further until day 6 after FGF2 = withdrawal. On the basis of these and previous results from = our=20 laboratory we concluded that the PDGF 3D"alpha-receptor=20 is the predominant receptor isoform during early stem = cell=20 differentiation.

Expression of PDGF receptors after = PDGF-AA stimulation=20

Because PDGF has been implicated in neuronal differentiation of CNS = stem=20 cells, we next investigated how receptor levels were = influenced by=20 differentiation in the presence of PDGF. Western blot = analysis was=20 used to study expression and phosphorylation of PDGF = receptors in=20 neuroepithelial cells after PDGF-AA stimulation. Subconfluent = cortical stem cells were grown for 1, 2, 4, and=20 6 d after withdrawal of FGF2, in the presence of = 10 ng/ml=20 of PDGF-AA, and compared with proliferating stem cells = (FGF2).=20 Because previous investigators (Williams et al., 1997) = suggest that a=20 short exposure to PDGF suffices to stimulate neuronal=20 differentiation, parallel cultures received a single dose of=20 20 ng/ml PDGF-AA on day 0, after which they were = kept in=20 plain N2-medium.

Figure 2A=20 shows that the PDGF 3D"alpha-receptor=20 expression level remained constant throughout the experiment, in which = cortical=20 stem cells were treated continuously with PDGF-AA. In = cultures=20 treated with a single dose of PDGF-AA, the PDGF 3D"alpha-receptor=20 expression level decreased 4 d after withdrawal of FGF2 = (Fig. 2B).=20



View = larger=20 version (28K):
[in=20 this window]
[in a new window]
  		Figure 2. =   Western=20 blot analysis of PDGF receptor expression and = phosphorylation in CNS=20 stem cells after PDGF-AA stimulation. Immunoprecipitation of = cell=20 lysates was performed using antibodies to PDGF 3D"alpha-receptor and PDGF 3D"beta-receptor. Anti-PDGF 3D"alpha-receptor antibody, anti-PDGF 3D"beta-receptor antibody, or anti-phosphotyrosine = antibody=20 was used for immunoblotting. Lysates were made from cortical = stem=20 cells grown in the presence of FGF2 (at the start of the=20 experiment), from cells treated continuously with PDGF-AA = after the=20 withdrawal of FGF2 (A), and from cells stimulated = with a=20 single dose of PDGF-AA at the time of FGF2 withdrawal = (B).=20

After PDGF-AA stimulation, phosphorylation of the PDGF 3D"alpha-receptor=20 in cortical stem cell cultures reached a maximum the first = day after=20 stimulation. Thereafter, the level of receptor phosphorylation=20 decreased but was maintained at a level higher than that of = control=20 cells (Fig. 2A).=20 The phosphorylation level in cells that received a single = dose of=20 PDGF also decreased after a peak on day 1 and reached = control=20 levels at 4 d after stimulation (Fig. 2B).=20

Similarly to cortical stem cells grown in the absence of PDGF, the = PDGF -receptor level for PDGF-treated cells was very low = at=20 the beginning of the experiment, but the expression increased = as the=20 cells differentiated. In contrast to cultures differentiating = in=20 plain N2-medium, in which a distinct phosphorylation of the = PDGF -receptor was seen at days 4 and 6, no = phosphorylation=20 of the 3D"beta-receptor=20 was detected in cultures treated with PDGF-AA (data not=20 shown).

PDGF induces c-fos RNA expression

In our examination of cellular events initiated by activation of PDGF = receptors, we next studied expression of the immediate-early = gene=20 c-fos in response to PDGF-AA. We first incubated cortical = stem=20 cell cultures for 3 hr in N2-medium without FGF2 to minimize=20 possible c-fos background expression. Cells were then=20 stimulated with PDGF-AA and harvested for RNA preparation = after=20 10 min, 30 min, 1 hr, and 2 hr. Control = cells=20 were incubated for 3 hr without FGF, after which RNA was = prepared. In Figure 3=20 the ratio of c-fos RNA to GAPDH RNA is shown. The=20 PDGF-AA-stimulated c-fos expression displayed a = maximal=20 induction of 50-fold the control level at 1 hr. At = 2 hr the=20 amount of c-fos RNA had declined but had not yet = reached that=20 of control cells.



View = larger=20 version (17K):
[in=20 this window]
[in a new window]
  		Figure 3. =   Northern=20 blot analysis of c-fos expression in cortical stem = cells=20 after PDGF-AA stimulation. Cell cultures were incubated = without FGF2=20 for 3 hr, stimulated with PDGF-AA, and harvested for = RNA=20 preparation after 10 min, 30 min, 1 hr, and=20 2 hr. The levels of RNA expression are given as the = ratios of=20 c-fos to GAPDH pixels.

PDGF-AA stimulation of BrdU incorporation =

To investigate whether PDGF-AA can stimulate DNA synthesis in = cortical stem=20 cells, cultures were pulse labeled with BrdU for 14 hr = and=20 stained with an anti-BrdU antibody. The BrdU incorporation in = FGF2-cultured cells were 86 =B1 2.9% (data not shown). = Cells=20 grown in the absence of FGF2 were compared with cells treated = once with PDGF-AA, at the time of FGF2 withdrawal, and cells = treated=20 continuously with PDGF-AA (Fig. 4).=20 Counting of BrdU-positive cells revealed that treatment with = PDGF-AA=20 gives a fourfold increase in BrdU incorporation 2 d = after=20 stimulation, compared with control cultures that received no = PDGF. In=20 cultures receiving a single dose of PDGF, the amount of cells = incorporating BrdU had declined to that of control cells = after=20 4 d. In cells treated continuously with PDGF-AA, the = number of=20 BrdU-positive cells remained significantly higher after = 4 d. In=20 all PDGF-treated cells, BrdU incorporation levels had = declined to=20 that of control cells after 6 d.



View = larger=20 version (29K):
[in=20 this window]
[in a new window]
  		Figure 4. =   BrdU=20 labeling of PDGF-AA-stimulated cortical stem cells. Parallel = stem=20 cell cultures were untreated, treated once with PDGF-AA, or = treated=20 continuously with PDGF-AA for 2, 4, and 6 d. = Before=20 fixation the cells were exposed to BrdU for 14 hr.=20 Incorporation of BrdU was detected using anti-BrdU = antibodies.=20 Stained cells (duplicate dishes) were counted (in seven = parallel=20 fields; 200=D7 magnification) and plotted as the ratio of=20 BrdU-positive cells to the total cell number. = *** denotes=20 p < 0.001.

PDGF-AA treatment increases the total = cell number

To further clarify the mitogenic effect of PDGF-AA on cortical stem = cells, we=20 performed cell counting experiments. FGF2-treated cells were=20 harvested and counted at the start of the experiment. After = FGF2=20 withdrawal, cultures were left untreated, treated once with = PDGF-AA,=20 or treated continuously with PDGF-AA. The total cell number = was=20 measured using a Coulter Z1 cell counter, on days=20 2, 4, 6, and 8 (Fig. 5).=20 A fourfold increase in total cell number was observed in = cortical=20 cultures treated continuously with PDGF-AA, compared with = untreated=20 cultures, at day 8. The increase in total cell number = was lower,=20 but significant, in cultures treated with a single dose of = PDGF-AA.=20



View = larger=20 version (31K):
[in=20 this window]
[in a new window]
  		Figure 5. =   Total=20 cell number in cortical cultures after PDGF-AA treatment.=20 FGF2-treated cells were harvested and counted at the start = of the=20 experiment. After FGF2 withdrawal, parallel stem cell = cultures were=20 untreated, treated with a single dose of PDGF-AA, or treated = continuously with PDGF-AA for 2, 4, 6, and = 8 d.=20 The total cell number was measured using a Coulter Z1 cell = counter.=20 * denotes p < 0.05, **=20 p < 0.01, and ***=20 p < 0.001.

PDGF treatment retains an immature phenotype that can = be=20 stained with neuronal markers

To further investigate the effect of PDGF on cortical stem cell=20 differentiation, cells were stained with antibodies specific = to the=20 neuronal marker, MAP2. Cells were grown for 2, 4, or=20 6 d without FGF2 in the absence or presence of PDGF. = Parallel=20 cultures were untreated, received a single dose of PDGF-AA, = or=20 received a daily dose of PDGF-AA (Fig. 6).=20 After fixation, the cells were stained with MAP2 antibodies = to reveal=20 neuronal differentiation. Parallel cultures were stained with = antibodies to nestin. At the time of FGF2 withdrawal, close = to 100%=20 of the cells were nestin positive, and this number declined = during=20 the course of the experiment, as the cells differentiated = (data not=20 shown). In cultures grown in the presence of FGF2, very few=20 MAP2-positive cells were seen (Fig. 6A).=20 In untreated cultures, MAP2-positive cells started to appear = 2 d=20 after FGF withdrawal, indicative of neuronal differentiation = (Fig. 6B).=20 The intensity of MAP2 staining in control cultures increased = with=20 time (Fig. 6E,H),=20 and 6 d after FGF2 withdrawal (H) most the cells = had=20 differentiated. The MAP2-positive neurons now had a more = mature=20 phenotype with extended processes (Fig. 6H).=20



View = larger=20 version (109K):
[in=20 this window]
[in a new window]
  		Figure 6. =   Staining=20 of PDGF-AA-treated cortical stem cells with neuronal = markers. After=20 fixation, the cells were stained with MAP2 antibodies. = Control=20 cells, grown in the presence of FGF2, were fixed at the = start of the=20 experiment (A). Cells were grown for 2 d=20 (B-D), 4 d (E-G), or = 6 d=20 (H-J) without FGF2 in the absence or presence = of PDGF.=20 Parallel cultures were untreated (B, E, = H),=20 received a single dose of PDGF-AA (C, F, = I), or=20 PDGF-AA was added daily (D, G, J). The = cells=20 were photographed at 200=D7 magnification.

Cells treated with a single dose of PDGF-AA showed the same type of=20 differentiation pattern (Fig. 6C,F,I)= ,=20 but the differentiation process was slightly slower, with = more=20 immature MAP2-positive cells at days 2 and 4 than = in the=20 untreated cultures. In contrast, the MAP2-positive cells in = cultures=20 treated continuously with PDGF-AA did not differentiate into=20 process-extending neurons (Fig. 6D,G,J)= =20 during the course of 6 d. Still, at the end of the experiment=20 (J) only a few cells showed morphological maturation. The=20 MAP2-positive cells rather display a rounded morphology, and = many=20 cells appear in clusters. Together with the data from the = BrdU=20 incorporation and cell counting experiments, these results = manifest a=20 mitogenic effect of PDGF-AA on cortical stem cells during the = early=20 stage of neuronal differentiation. Parallel experiments were=20 stained with an antibody to Tuj1, another commonly used = neuronal=20 marker, and an identical staining pattern was observed (data = not=20 shown).

MAP2-positive progenitor cells incorporate BrdU in=20 PDGF-AA-treated cultures

To further investigate whether dividing cells are neuronal = precursors, we=20 used double staining of cortical stem cells with antibodies = to MAP2=20 and BrdU (Fig. 7).=20 Cells were grown for 2 or 4 d without FGF2 in the = absence=20 or presence of 10 ng/ml PDGF-AA. Before fixation, the = cells were=20 pulse labeled with BrdU for 14 hr. The cells were first = stained=20 for MAP2 and photographed, using a computerized microscope. = After=20 subsequent staining with BrdU antibodies, the same fields of = the=20 culture dish were photographed again. A high proportion of = cells=20 grown in the absence of PDGF for 2 d were MAP2 positive = (Fig. 7A)=20 and BrdU negative (Fig. 7B,=20 Table 1)=20 and extended short processes. Cells grown in the presence of = PDGF-AA=20 showed an undifferentiated phenotype 2 d after FGF2 = withdrawal=20 (Fig. 7C).=20 Staining with antibodies to BrdU indicated that a population = of the=20 cells treated with PDGF-AA for 2 d were positive for = both MAP2=20 and BrdU (Fig. 7D,=20 Table 1).=20 After 4 d of differentiation, the PDGF-treated cells = still=20 showed an immature phenotype, but the amount of = double-positive cells=20 had decreased to control levels (Table 1).=20 Untreated cells had a more differentiated phenotype with long = processes (data not shown).



View = larger=20 version (172K):
[in=20 this window]
[in a new window]
  		Figure 7. =   MAP2 and=20 BrdU double staining of PDGF-AA-treated cortical cells. Stem = cell=20 cultures were untreated (A, B) or treated with = PDGF-AA=20 (C, D) for 2 d after FGF2 withdrawal. The = cells=20 were exposed to BrdU for 14 hr, fixed, and stained with = MAP2=20 antibodies (A, C). Defined fields of the = culture dish=20 were photographed using a computerized microscope. The = cultures were=20 subsequently stained for BrdU, and the same fields were = photographed=20 again (B, D).


        &= nbsp;           &n= bsp;         
View=20 this table:
[in=20 this window]
[in a new window]
  		Table=20 1.   Percentage of MAP2 and BrdU = double-positive=20 cells=20 =

PDGF-AA is involved in control of stem = cell survival=20

We next investigated whether the increase in cell number, seen after = addition=20 of PDGF-AA, results from increased cell survival in addition = to the=20 effect on proliferation. Staining for apoptotic nuclei using = a TUNEL=20 assay revealed no differences between PDGF-AA and untreated = cultures=20 at 2 d of differentiation, but at day 4 we detected = a=20 twofold decrease in TUNEL staining in PDGF-AA-treated = cultures (Fig.=20 8A).=20



View larger = version (17K):
[in=20 this window]
[in a new window]
  		Figure 8. =   Cell=20 survival studies of PDGF-AA-treated cortical stem cells. A = TUNEL=20 assay was performed on cells grown for 2 and 4 d = in the=20 presence or absence (no addition, no add.) of = PDGF-AA. Cells=20 grown in the presence of FGF2 were included as a control. = Cells=20 going through apoptosis were counted using a fluorescence = microscope=20 and plotted as the ratio to total number of cells = (A). ***=20 denotes p < 0.001. Western blot = analysis=20 was used to study PKB/c-Akt phosphorylation in CNS stem = cells after=20 FGF2 and PDGF-AA stimulation compared with untreated cells = (no=20 add.) (B). Total cell lysates were used for=20 immunoblotting with anti-PKB/c-Akt antibody (Akt) and = anti-phosphorylated PKB/c-Akt antibody (p-Akt).

The serine threonine kinase PKB/c-Akt has been linked to increased = cell=20 survival. In addition to the TUNEL assay, we studied the=20 phosphorylation of PKB/c-Akt as a measure of increased cell = survival.=20 Proliferating stem cell cultures were stimulated for = 5 min with=20 100 ng/ml PDGF-AA or 100 ng/ml FGF2, and total protein=20 lysates were performed. Cell lysates from parallel cultures,=20 receiving only medium, were used as a control. Figure 8B=20 shows that PDGF-AA stimulated a moderate PKB/c-Akt = phosphorylation.=20 FGF2 treatment also resulted in stimulation of PKB/c-Akt=20 phosphorylation, but the level was lower than in PDGF-treated = cultures. No phosphorylated PKB/c-Akt was detected in = untreated=20 control cells. Total PKB/c-Akt levels were not found to be = affected=20 by PDGF-AA or FGF2 stimulation.


    DISCUSSION
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

Multipotent neural stem cells can be maintained in monolayer cultures = in the=20 presence of FGF2, and on withdrawal of the mitogen give rise = to=20 neurons, astrocytes, and oligodendrocytes (for review, see = McKay,=20 1997). = The=20 experiments described in this study were performed on stem = cell=20 cultures from the E15 rat cortex in their first passage. This = provides a culture system with homogeneous cells, with = respect to=20 morphological criteria and staining for the intermediate=20 filament nestin.

The influence of exogenous factors on differentiation of CNS stem = cells has=20 been addressed in several studies. Although the pathway of = astrocytic=20 differentiation induced by CNTF has been studied in detail = (Bonni et=20 al., 1997; = Rajan and=20 McKay, 1998),=20 less is known about the development of the neuronal lineage = in=20 stem cells. Two reports (Johe et al., 1996; = Williams et=20 al., 1997)=20 have suggested that PDGF-treatment of cortical progenitor = cells=20 leads to an increase in the number of neurons. In the study = by=20 Williams et al. (1997), a = different=20 cell culture protocol was used, and cortical cells were = treated with=20 PDGF-AA without previous expansion of stem cells. Therefore, = their=20 data cannot be directly compared with our results. The = present=20 investigation uses the method described in Johe et al. = (1996). = These authors=20 raise the possibility that PDGF does not act as an = instructive factor=20 like CNTF, a statement that fits with our data. =

PDGF is active either as a homodimer (AA, BB) or heterodimer (AB). = Activation=20 of PDGF receptors is brought about by ligand binding to = dimerizing=20 receptor subunits 3D"alpha or=20 3D"beta. The BB homodimer can only bind to 3D"beta-receptor=20 subunits, whereas PDGF-AA can activate both 3D"alpha- and=20 3D"beta-receptors (Westermark and Sorg, 1993). = The AA=20 homodimer, however, has a slightly lower affinity for the = -receptor. In accordance with our previous = data, we=20 detected PDGF 3D"alpha-receptor expression already on dissociated = cortices at=20 E15. In contrast, the 3D"beta-receptors=20 were hardly detected in uncommitted cells, suggesting that in = cortical stem cells the 3D"alpha-receptor=20 is the predominant receptor isoform. Therefore we chose to = use=20 PDGF-AA as the ligand throughout this study.

Tyrosine phosphorylation of the PDGF 3D"alpha-receptor=20 was not seen in dissociated cortices, in analogy to previous = investigations=20 (Williams et al., 1997), = and during=20 differentiation, induced by discontinued addition of FGF2, we = could=20 not detect PDGF 3D"alpha-receptor phosphorylation using = phosphotyrosine=20 antibodies. The cortical stem cells responded to addition of = PDGF-AA=20 by receptor phosphorylation, such that a prolonged exposure = to the=20 ligand gave rise to a sustained receptor activation. This = prolonged=20 tyrosine phosphorylation, however, never reached the level = seen=20 during the first day after stimulation, suggesting receptor=20 downregulation in response to the ligand. In lysates prepared = from=20 cells that were given a single dose of PDGF, phosphorylation = of the=20 3D"alpha-receptor returned to background levels more = quickly=20 than in cells exposed continuously to PDGF-AA.

In contrast to the PDGF 3D"alpha-receptor, the 3D"beta-receptor=20 is barely detectable during the first days of differentiation in = cortical=20 stem cells, and we could see no phosphorylation on tyrosine = residues=20 in response to PDGF-AA. Therefore, we conclude that the = increased=20 BrdU uptake and total cell number after PDGF-AA stimulation = are=20 mediated through PDGF 3D"alpha-receptors. During differentiation induced by=20 withdrawing FGF2, 3D"beta-receptor=20 expression can be visualized by Western blot analysis.=20 Phosphorylation of the PDGF 3D"beta-receptor was also seen when cortical stem = cells=20 differentiated in the absence of PDGF-AA. Immunohistochemical = analysis of rat brain has shown that the PDGF 3D"beta-receptor=20 is expressed in neurons in many areas of the CNS (for review, = see=20 Valenzuela et al., 1997), = and it=20 has been reported that PDGF-BB exerts neurotrophic activity = on=20 neurons from newborn rats (Smits et al., 1991). = Additional=20 studies support the notion that PDGF-BB and the 3D"beta-receptor=20 are involved in survival and proliferation of neurons = (Giacobini et=20 al., 1993; = Nikkhah=20 et al., 1993). = In view of=20 these findings it is likely that the 3D"beta-receptor,=20 detected after several days of differentiation, reflects = expression=20 on neurons. However, the exact stage of maturation at which = the -receptor starts to be expressed remains to be=20 determined.

Expression of immediate-early genes is induced in various tissues in = response=20 to a wide range of extracellular cues, for example, PDGF = (Cochran and=20 Weissman, 1984; = Greenberg and=20 Ziff, 1984; = Kruijer=20 et al., 1984; = M=FCller et al.,=20 1984). = Among the=20 immediate-early genes are common transcription factors, but = also=20 genes that are more restricted to differentiation of a = specific cell=20 lineage (for review, see Herschman, 1991). = Core=20 transcription factors include c-Myc and c-Fos, both of which = are=20 activated by PDGF in many cell types. PDGF-AA-stimulated = c-fos=20 RNA expression in cortical stem cells peaked at 1 hr, = suggesting=20 that it is mediated by signaling through PDGF 3D"alpha-receptors. The possibility that c-fos = activation=20 is a secondary phenomenon is less likely, because of the time = frame of induction.

From MAP2 (and Tuj1) staining of differentiating cortical cultures, = it is=20 evident that exogenous PDGF has a profound effect on cell = morphology.=20 The presence of PDGF-AA after withdrawal of FGF2 almost = completely=20 abolished morphological neuronal maturation. Instead of = extending=20 elaborate processes as in control cultures, PDGF-AA-treated = cells=20 retained a rounded immature phenotype even after 6 d. It = is=20 interesting to note that a single dose of PDGF, at the time = of FGF2=20 withdrawal, is not sufficient to obtain the same effect on=20 differentiation. Cell culture medium is changed every second = day, and=20 any residual PDGF is washed out from the culture at that = time. Thus,=20 the presence of PDGF over several days of differentiation is = needed=20 for the effect reported in this investigation.

The immature morphology of PDGF-AA-treated stem cell cultures could = be caused=20 by a block in differentiation, a continuous proliferation, or = an=20 increase in cell survival, or a combination of these. = Previous=20 investigators (Johe et al., 1996) = and our=20 unpublished observations have shown that PDGF cannot = substitute FGF2=20 as a major mitogen for cortical stem cells. When FGF2 is not=20 present, however, our data from BrdU incorporation and cell = counting=20 experiments show that PDGF is able to stimulate division of = stem=20 cells. Both a single dose and renewed addition of PDGF-AA = gave a=20 fourfold increase in BrdU-positive cells at 2 d, whereas = at=20 4 d a continuous presence of PDGF was needed to yield a = higher=20 percentage compared with control cells. Double staining for = MAP2 and=20 BrdU reveals a population of cells that express a neuronal = marker=20 while still dividing.

The possible effect of PDGF-AA on cell survival was investigated. = TUNEL=20 staining revealed that the amount of cells going through = apoptosis=20 during the earliest phase of differentiation (2 d) is = similar=20 between control and PDGF-treated cultures. At 4 d of = differentiation,=20 however, the number of apoptotic nuclei was reduced by half = in=20 the presence of PDGF. Activation of PKB/c-Akt has been linked = to reduced apoptosis (Kandel and Hay, 1999) = and was shown=20 to act as a survival factor for cerebellar neurons (Dudek et = al.,=20 1997). A=20 modest phosphorylation of PKB/c-Akt was also seen in response = to=20 PDGF-AA. Thus, in addition to stimulating stem cell proliferation,=20 PDGF also exerts a cell survival effect.

Our results fit with the notion that PDGF stimulates a neuronal fate = of stem=20 cells, although not as an instructive agent but rather to = expand a=20 pool of immature neurons before their morphological = maturation=20 occurs.

PDGF-AA and the 3D"alpha-receptor=20 play an important role in the development of the oligodendrocyte = lineage. A=20 recent report points at an unexpected plasticity of early=20 oligodendrocyte progenitors (Kondo and Raff, 2000). = To evaluate=20 the differentiation capacity of the MAP2+/BrdU+=20 progenitors in this study on treatment with agents that = promote=20 oligodendrocyte development, such as T3, is therefore = greatly=20 warranted.


    FOOTNOTES

Received June 12, 2000; revised Feb. 12, 2001; accepted = Feb.=20 23, 2001.

This study was supported by grants from the Swedish Cancer = Foundation, the=20 Children Cancer Foundation of Sweden, Magnus Bergwall's = Foundation,=20 Wiberg's Foundation, and Selander's Foundation. We thank=20 M. Lindstr=F6m for excellent technical assistance.=20

Correspondence should be addressed to Karin Forsberg-Nilsson, = Department of=20 Genetics and Pathology, Rudbeck Laboratory, Uppsala = University,=20 SE-751 85 Uppsala, Sweden. E-mail: karin.nilsson{at}genpat.uu.se .


    REFERENCES
TOP
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES =

  • Auffrey C, Rougeon F = (1980)=20 Purification of mouse immunoglobulin heavy-chain messenger RNAs from = total=20 myeloma tumor RNA. Eur J Biochem 107:303-314[ISI][Medline].
  • Bonni A, Sun Y, = Nadal-Vicens M,=20 Bhatt A, Frank D, Rozovsky I, Stahl N, Yancopoulos G, Greenberg M = (1997)=20 Regulation of gliogenesis in the central nervous system by the = JAK-STAT=20 signaling pathway. Science 278:477-483[Abstract/Free Full Text].
  • Bottenstein JE, Sato = GH (1979)=20 Growth of a rat neuroblastoma cell line in a serum-free supplemented = medium.=20 Proc Natl Acad Sci USA 76:514-517[Abstract/Free Full Text].
  • Cochran MD, Weissman C = (1984)=20 Molecular structure of b-globin and the TK promoters. EMBO J = 3:2453-2459[ISI][Medline].
  • Dudek H, Datta SR, = Franke TF,=20 Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME = (1997)=20 Regulation of neural survival by the serine-threonine protein kinase = Akt.=20 Science 275:661-665[Abstract/Free Full Text].
  • Forsberg-Nilsson K, = Behar T,=20 Afrakhte M, Barker J, McKay RDG (1998) Platelet-derived growth factor = induces=20 chemotaxis of neuroepithelial stem cells. J Neurosci Res = 53:521-530[ISI][Medline].
  • Gage FH (1998) Stem = cells of the=20 central nervous system. Curr Opin Neurobiol 8:671-676[ISI][Medline].
  • Giacobini MM, Almstrom = S, Funa=20 K, Olson L (1993) Differential effects of platelet-derived growth = factor=20 isoforms on dopamine neurons in vivo: -BB supports cell survival, -AA = enhances=20 fiber formation. Neuroscience 57:923-929[Medline].
  • Greenberg ME, Ziff EB = (1984)=20 Stimulation of 3T3 cells induces transcription of the c-fos = proto-oncogene.=20 Nature 312:656-658[Medline].
  • Hatten ME (1990) = Riding the=20 glial monorail: a common mechanism for glial-guided migration in = different=20 regions of the developing brain. Trends Neurosci 13:179-184[ISI][Medline].
  • Herschman HR (1991) = Primary=20 response genes induced by growth factors and tumor promoters. Annu Rev = Biochem=20 60:281-319[ISI][Medline].
  • Hutchins J, Jefferson = V (1992)=20 Developmental distribution of platelet-derived growth factor in the = mouse=20 central nervous system. Dev Brain Res 67:121-135[Medline].
  • Johe KK, Hazel TG, = Muller T,=20 Dugich Djordjevic MM, McKay RDG (1996) Single factors direct the=20 differentiation of stem cells from the fetal and adult central nervous = system.=20 Genes Dev 10:3129-3140[Abstract/Free Full Text].
  • Kandel ES, Hay N = (1999) The=20 regulation and activities of the multifunctional serine/threonine = kinase=20 Akt/PKB. Exp Cell Res 253:210-229[ISI][Medline].
  • Kondo T, Raff M = (2000)=20 Oligodendrocyte precursor cells reprogrammed to become multipotential = CNS stem=20 cells. Science 289:1754-1757[Abstract/Free Full Text].
  • Kruijer W, Cooper JA, = Hunter T,=20 Verma IM (1984) Platelet-derived growth factor induces rapid but = transient=20 expression of the c-fos gene and protein. Nature 312:711-716[Medline].
  • McKay RDG (1997) Stem = cells in=20 the central nervous system. Science 276:66-71[Abstract/Free Full Text].
  • M=FCller R, Bravo R, = Burckhardt=20 J, Curran T (1984) Induction of c-fos gene and protein by growth = factors=20 precedes activation of c-myc. Nature 312:716-720[Medline].
  • Nikkhah G, Odin P, = Smits A,=20 Tingstrom A, Othberg A, Brundin P, Funa K, Lindvall O (1993) = Platelet-derived=20 growth factor promotes survival of rat and human mesencephalic = dopaminergic=20 neurons in culture. Exp Brain Res 92:516-523[ISI][Medline].
  • Rajan P, McKay RDG = (1998)=20 Multiple routes to astrocytic differentiation in the CNS. J Neurosci=20 18:3620-3629[Abstract/Free Full Text].
  • Rakic P (1972) Mode = of cell=20 migration of the superficial layers of fetal monkey neocortex. J Comp = Neurol=20 145:61-84[ISI][Medline].
  • Rakic P (1990) = Principles of=20 neural cell migration. Experientia 46:880-891.
  • Sasahara A, Kott J, = Sasahara M,=20 Raines E, Ross R, Westrum L (1992) Platelet-derived growth factor = B-chain-like=20 immunoreactivity in the developing and adult brain. Dev Brain Res = 68:41-53[Medline].
  • Smits A, Kato M, = Westermark B,=20 Nist=E9r M, Heldin C-H, Funa K (1991) Neurotrophic activity of = platelet-derived=20 growth factor (PDGF): rat neuronal cells possess functional PDGF -type receptors and respond to PDGF. Proc Natl Acad Sci = USA=20 88:8159-8161[Abstract/Free Full Text].
  • Temple S, = Alvarez-Buylla A=20 (1999) Stem cells in the adult mammalian nervous system. Curr Opin = Neurobiol=20 9:135-141[ISI][Medline].
  • Valenzuela CF, = Kazlauskas A,=20 Weiner JL (1997) Roles of platelet-derived growth factor in the = developing and=20 mature nervous systems. Brain Res Rev 24:77-89[Medline].
  • Vescovi AL, Snyder EY = (1999)=20 Establishment and properties of neural stem cell clones: plasticity in = vitro=20 and in vivo. Brain Pathol 9:569-598[ISI][Medline].
  • Westermark B, Sorg C = (1993)=20 Cytokines (Sorg C, ed). In: Biology of platelet-derived growth factor. = Basel:=20 Karger.
  • Williams B, Read J, = Price J=20 (1991) The generation of neurons and glia from a common precursor = cell. Neuron=20 7:685-693[ISI][Medline].
  • Williams B, Park J, = Alberta J,=20 Muhlebach S, Hwang G, Roberts T, Stiles C (1997) A PDGF-regulated = immediate=20 early gene response initiates neuronal differentiation in ventricular = zone=20 progenitor cells. Neuron 18:553-562[ISI][Medline].=20

Copyright =A9=20 2001 Society for Neuroscience=20  0270-6474/01/21103483-09$05.00/0

This article has been cited by other=20 articles:=20

3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
K.=20 Chaichana, G. Zamora-Berridi, J. Camara-Quintana, and A.=20 Quinones-Hinojosa
Neurosphere Assays: Growth Factors = and=20 Hormone Differences in Tumor and Nontumor Studies
Stem = Cells,=20 December 1, 2006; 24(12): 2851 - 2857.
[Abstract]=20 [= Full=20 Text] [PDF]<= /A>=20
3D"" 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Cancer3D"Home
A.=20 Erlandsson, K. Brannvall, S. Gustafsdottir, B. Westermark, and K.=20 Forsberg-Nilsson
Autocrine/Paracrine Platelet-Derived = Growth=20 Factor Regulates Proliferation of Neural Progenitor=20 Cells
Cancer Res., August 15, 2006; 66(16): = 8042 -=20 8048.
[Abstract]=20 [F= ull=20 Text] [PDF]=20
3D"" 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
B.=20 Angenieux, D. F. Schorderet, and Y. = Arsenijevic
Epidermal=20 Growth Factor Is a Neuronal Differentiation Factor for Retinal = Stem Cells=20 In Vitro
Stem Cells, March 1, 2006; 24(3): = 696 -=20 706.
[Abstract]=20 [Fu= ll=20 Text] [PDF]=20
3D"" 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
R.-S.=20 Ge, Q. Dong, C. M. Sottas, V. Papadopoulos, B. R. Zirkin, and M. = P.=20 Hardy
In search of rat stem Leydig cells: = Identification,=20 isolation, and lineage-specific development
PNAS,=20 February 21, 2006; 103(8): 2719 - 2724.
[Abstract]=20 [Full = Text]=20 [PDF] =
=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
C De=20 Bustos, A Smits, B Stromberg, V P Collins, M Nister, and G=20 Afink
A PDGFRA promoter polymorphism, which disrupts = the=20 binding of ZNF148, is associated with primitive neuroectodermal = tumours=20 and ependymomas
J. Med. Genet., = January 1, 2005;=20 42(1): 31 - 37.
[Abstrac= t]=20 [Full=20 Text] [PDF] =
=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
Y.=20 Hirabayashi, Y. Itoh, H. Tabata, K. Nakajima, T. Akiyama, N. = Masuyama, and=20 Y. Gotoh
The Wnt/{beta}-catenin pathway directs = neuronal=20 differentiation of cortical neural precursor=20 cells
Development, June 15, 2004; 131(12): = 2791 -=20 2801.
[Abst= ract]=20 [Full=20 Text] [PDF]=20
3D"" 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Mol3D"Home
M.=20 Enarsson, A. Erlandsson, H. Larsson, and K.=20 Forsberg-Nilsson
Extracellular Signal-Regulated Protein = Kinase=20 Signaling Is Uncoupled From Initial Differentiation of Central = Nervous=20 System Stem Cells to Neurons
Mol. Cancer Res.,=20 December 1, 2002; 1(2): 147 - 154.
[Abstra= ct]=20 [Full=20 Text] [PDF] =
=20 		3D""=20

=
This = Article
3D"
3D"Right Abstract=20 3D"Freely
3D"Right Full=20 Text (PDF)
3D"Right Submit an eLetter =
3D"Right Alert=20 me when this article is cited
3D"Right Alert=20 me when eLetters are posted
3D"Right Alert=20 me if a correction is posted
3D"Right Citation Map
3D"
Services
3D"
3D"Right Email=20 this article to a friend
3D"Right Similar=20 articles in this journal
3D"Right Similar=20 articles in ISI Web of Science
3D"Right Similar=20 articles in PubMed
3D"Right Alert me = to new=20 issues of the journal
3D"Right Down= load=20 to citation manager
3D"Right 3D"reprints
3D"
Citing = Articles
3D"
3D"Right Citing=20 Articles via HighWire
3D"Right Citing=20 Articles via ISI Web of Science (33)
3D"Right Citing Articles via Google = Scholar
3D"
Google = Scholar
3D"
3D"Right Articles by Erlandsson, A. =
3D"Right Articles by Forsberg-Nilsson, = K.
3D"Right Search for Related Content =
3D"
PubMed
3D"
3D"Right PubMed=20 Citation
3D"Right Articles by Erlandsson, A. =
3D"Right Articles by Forsberg-Nilsson, = K.

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF=20 CONTENTS
=0A= =0A= _uacct =3D "UA-1707495-1";=0A= =0A= urchinTracker();=0A= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/banner/title.gif R0lGODlh3AAsAKIAADMzM5eXl3p6ellZWcDAwOfn5wAAAP///ywAAAAA3AAsAAAD/3i63P4wykmr vTjrzbv/YCiOZGmeaKqubOu+cCzPdG3feK7vfO//wKBwSCwaj8ikcslsOp/QqHRKrVqv2Kx2y+16 v+CweEwum8/o9JfAbrcLB3aoILfVL4RAoEEnwBd0fzx9LQAGh4iHAQQGAyGMAHaNGAOHkQwCh44L lQQ+AZMsAqOGAKMCBZl7IJkCNqCrFQUGAIKclgyGPwQCni+VsQedIYa+NMMWoK4OlgZ/s5doxbnO vMYKeb0Vh4IFAdoLbM9+B33ee+LWDdnXug/sCnTA1+W0wNgGy9gCi4Dk5XXk8PoDj4E3cIC+XbsT h183P+dsxdEj8eC1WQYM0koUq/8SomgQIC3I9PGPIZPO4mzMh9GQonguDy2D5qBAzEmMEq3Lp0yB Kmw3ffVUuazUoXI3NwlLpJSkTHybCAT1uZIbzETGnNIKt5WrgUWVNmUaQOeoBFCbQAFgM+1AV7cZ D5Dkx0ZRqq5jy15ipO/WgLoZ9TKUa6DuJWSG9qil6utnSz1L/+ZUAOrr5ANq83SFpSAx5lCV1kot 3LkRgUrL1BawSZpw31b4XGFEOeHegZOMVUbt6pnq7mUCatW79FNjtGmMlFKDY9UsWnyXcN9OKTLe 22m9R5WGQ3Opp+cqo6ec7qk63+2lfSFDTxhdKLgTkL8fxvnzMrMKkBVvKAB1+gb/9U1H2VcPdNVJ d8gkp8BbZu0XoDseocKVcgtA2JqC3QnYngPVTfeHVQvgh5tWuEjQYD4VpqQfaRlq6B1SHxEIXwPI INgaAwradx5ciRCYY3fSvTjcVbQ0hiIfXfX40o5A3rhAZT1aFxdUIcaVmBv09FZdjbxNidtQQ5aW XyNwDNPiglPm6A6AR0KSiSfQYAlHfUPhN6NuDEA5Jj14xukGHMXtaOcti7gBXZ5HNvmkhAwcYmRR rT3XXXdvcjVTknFhFBszU95z5p5V4lZdKqsgY+Zbd97zDXdmtTUAcT52RSp7xclqyn+YgQPbSJEe KSqIVZbn6H+sCXtYKEFWStSC1cfCyqdVOcGxYwNrTtfVlsiSFq19jVLXnDOsifedgdqSu4mI41nl H3kqjdcWra2F5lIwpa3UVDNtWuLSfSBJp6y+mrBHDQAuGUkvs5gEXA8tLqFEMCK5pfhwa0YNS9hK vrjTUsNh3llKKX+QtO9IjPqkz6rxvArAXw8U8CotwbhMMADBBGfKQOXwk+fJjEq1sjpy9RWOyixT VjIgOiON0GkEl+zzX0mjPDTBRcdBtDGpUC1I0lY3/QxCXDNtSjc2V63G2WinrfbabLft9ttwxy33 3FUkAAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: application/octet-stream Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/adsystem/graphics/1200840225896/jneuro/AdultNeur220.gif?ad=16568&adview=true R0lGODlh3AAoALMAAMMaIIQTFt/a2IqfMJ9/fWtQR08JCQCaRa+inmxyIjgxJrzDNr9XQ9LAvwAA AP///yH5BAAAAAAALAAAAADcACgAAAT/0MlJq704B8DD7lwYekb5AR5qZJYxevDHLPQyMDDqGEWS KKZAaSgcGk/H4soQa3oSA9uolDhYFTuRdgtYTbySgvVaPWBZ6DQ6lwIQCIyRiEGvMwpMEkXBP+8V BSN3BTghNTRaBAViBz9GQY9JeSRMRJMbJJgBBVEDMHllZydcXGAUBmNXVgVqGQQIfq0UJ5gMDw8E OSG2t729ArlLJQ23DRUGBLeFAcS3JwK+0bcIq5CXediVJh1ELyLbKAFQAwVKAQONEi6k7EIWCqmA V7IOCggIrAQCAg1897FpRnlAcEsAOA68cN3R96tJswYl1AVI9gDPhmYC2jQQcK/ZAwSv/xoQaITH 0qQXTlI0YRcuRAkFA2J2EBczgTqWKNu421EvFSOAaBRwRLBRABaCDe4ZlbUlgC8goxKWK0LxQYMT D48A4GWRWbE8AMZB6VVAQYJFZz8F4ZKyTbhRTT8IMXsgSpxNnVhlwdlSYER5qebJAikBAb83GxEU hlU2zZaquMAiJCvX661cHLKu5RUkq4xDlBnELKSCSTu1krnBzUlCzDhPNBck8LIOxWkQIOYGHgP0 3ZtkBOxBtAfLQdICBPkJ0JtBSwBov05upTwTQEMUnidxNp11To3QouNwq726S5HzIgLsKP/2bblx eGMCkYgzhuQcjAL3ttBA5L7EQCED0v9yDhBgDAtT8FIVDjlIJZBHmHgWA2cpPBTVd7eUQ8cNtgnh 1mpOpLYEe+3RUQ4n5LxWhAQk5qSAfS6Ihg5vpmCgwIENMIfGK/UIgMYLBCFgQC8IxDBdhgIRhKRl EJm2AYUXFTMKJzRQlkAdztECFyVByNUNKW3MAFsCNkQhGyXrNZXleU2IZgNvaRhoFUf0cKTPfhK0 l6EBEKoQgFSmhVDVVJo1eIsLUVoF1wwLWImlc96kp8RJk/KFEA0DXHnIAjPttBZrbzkBxZtmnNJC f4aV1ceqZ7DKB3LE8LNfDMmVUFUuHjo4yqCJNnkChZlJqQWjoXG4ZnspEYHaQaHq4ib/DXTUIN5b YDziRLMwuDljqV9YcI8DBfSjSCyu7qHqcndeIBd0/UH3QEbZkkVeAEo+wJ2wcxz6QXfeNYrko5K2 VRmbkQQajgmbmWkDowuIp4t6X5j0cJcowvkFxBTkCG6OwdGzyI1YaGzBLtL4Us5kSKYHnUG9Lqov dl9tUeW/dGgp8JYeVqvJstfG1AnDA7Tn0g5dsjmFwYGZwoQFPIqkQMeLsLKIAWdQfcYiBea41MjB GjREAUTKQB3Jl62DEVwUBcqvd8WepdrNbEVEX7OfijBOw4wGbaRLl6TwZWknbDvbKRhPIBSdBQSn SD3j2oOFPQSsMHWB7/YWQtlEuJuC/4MiePQiAAPUCxcxEO2Lrxb+VvTnaG+nJIdz1na60hYoNvza VLq05GdOM1m0VUwWS1TBjR+FsQgBEyBXWFm/SY5HYbJyreSLJ9zKBOfBlv3nAlUhIAJFkYewtgip n8i6h8mSiFpb1W0h4w0+x2TO3ri9cP1cX+tH+B7AhGv8GxRAjj2Y9wbnrUAoTxPZBDgADZaJAGwF YQIEFcIAw/QichuQSb2GghGDYeQN9/AeB6qSgD9diUFtURbO1ocS3bmvJuOoCzmK5ha22IcPQyjD KjzlAQoQZWPGs0cFElccyBkQXD5yAJ0ocKTwqYwyE5QGPvIwA/FAhkip8Ug0xFOvH/9sIi03o4RA 2JAJ1shlWPGrSU36lrsVirEE+dkhxpY2AQMJRS+Je1UfPha5ekQtaktYTgGAUQGETAUlWJsKD/4I SHCEp3e/CUYNTUSERbSBAD74GCBOJjtNqNBS2KqfCNLoA5+ZsYXV+QQQDFCGKjhifz7ERfKCs8lN gktVuASkBA6nIxZ10gnrKZha2mAsM5YHbiiAgg8A4TbcNAFhNbRU7rKEIp8RopTToh+2ksUDK2Sq EQCR2wSClDzmOYAwiltBcaD2vB1AAyhzwB2MCDEhS3qgDvfEGxcAthU70AEnoQshAoLmQtQk7jfT mkNCAfZPSVGpJvckgLHw+atISgr/B1PTYQLu8QYdmSJcN0LeLZ92vMUtLo8CnJxxFCGSQqJMnq1R Rjjc5YurTKQXpLmcokZYMqvsU4u9aACDUIIMmv6CACIwKr6UoSVOTONkQO2FRqQotmLQ5QD1esoF klKPA/ExDCY1nGJI+jyhSIAfLj0SvFTCA2dEqCCRxBWvtAANm7qBLMgJ2/eC+gN7hG1nz7kgEBI3 DazANZIpGJsHnIoL6t0qkveKjFA+0oYLshKrBcECRXozyEV4tSx6iZziQPuxPy4hR0TpJdkURYsh 2QsGmlEWr0ZBOtNUxQSiq2pjzcK8CzZhZSpMxiEBUCgj+aIJnIBGV6qySiLwQkh5/6iIkywLBeis MmsZGKQswdWxFjzuu7f0QpDgibLCUktfHpBQDGZrWAzeFb3YA65ZMrUJCMFgUJT6k2TUW9mGwCC5 0vUAc6mXAvA5qWjUHUAvhqAGBbxLat1tBdb4tA/LlbewMThUHtQbDvyygRgYvOnLdGW9c8SkHLeC AXAvESrxfcVm0VhrdQMs4gfwNgcUcSDdEmxZCeNjOYB4VdTI9cdaclWBs0BBQnwLg1s4ALYvbgJ7 oRzi226gXhteMBN8VkKnSOlPlhXjzlxsFSdlOBpFMrFybbtgHwShKkKtoQd43OM0oBMfG4mxSBji i8MMsjAirUC8kuILXHl5Eh9EqP+AKWMfEOfBygkJMXDvCdHA6svDSXBCot/AgEpcxhf4iMmaF32Z EOLKOn02dJPLBgWgFocFg3zaWF1Fa1bxwBh3VNc9y5xVXKHXMtHAIH675GhSz6kgJZlzlMOSST4t uMYlQRgbgV3oIRwKMgiY8XJLVroa/wKFXsYFTRKg1EBjQB/7IAw9Ejgnc89i103q9aGh/ODjWWTY RCi2t7U8iaBOogfL9AgThv2JiSAHhRiJmiJMoGHINIDcNB5USWOg3T6fubHKpJc0enmB1HK1FUJR Sjt1DeZu91rDw/hKEjA9BH3fKsyrfte/feCDSVvvErpikrWU/eiaEmPbKOdBl4v/kFdGhzs4PsCB rUBt57Fuzc7I8x8LBo2NrKJc533Dd8sjY2wDuEueAo8BzROAxbZijuLySnmZU/LrK0Zcy4v1waSQ YVkmCFbuXHJXGmJ9oxByvED8MIwiCDl1eE/C69FAtMqlnHYjQCNyA1/wBFlm7K48YaN1D7fX0L4n tXe7Cb/WuMl6HnqAQ2UI0IG8azE+9CFURQ2G2Qcw0kUUWBjIsxxp6RoMrxaaKr7MfSM75obgYOku XcMeUbW/M1HzCJKe6/+VV3qjDPrXxl2LFqF76PHSj3xr7+i8RUCnTQDBJKahD0sZ5HGUpBcCtYLq 2mCCu37vK7F7JNmWJpr27WV3/6nel8n0RmMe8HWfMEFdwV+rFgQ0Vy/Rdlt9QxDBwXAapmy40AOH EwRK4m5xknvvIgH6YBgboYGFJ2KHt1hwZxmz9xtfJHzT8AqNt38mUBWUV2M2xQDJVzQV9xGEwGc2 ZgKb9gYm2IPiQHOWlmyPpYIGoCSzMVmREV2XEWTTEHkyRw9hMEUguBQkRYX/Z33oswkTGG7SIHSA EFXLYQkClwfuomrhwm1lMW1WRyRVA4aJB2YBNnYDaHzUNnoMUG5BkBD98CJv2A9UeAF2NIjvtlj4 dwlTkwcfQ3xTYxZEF0l6QTF4gH+bQDXRVglP8xttCAgpxAORNB9HcAdY8BJTg36IVECE/1VJbfg1 yQaKzbMe/1VLRbCJb9BcDGaIuiho6zNMXMIlBSN3BbNzwHh4wjSMZoF3zzSMRqB/zGgEAAdGc/eM 1oBDNLRJrfiMerCL3PhkN0NDPENxyshN00aOyygqy/SJzOiMkaAEzKSKvfhGxPhFUNEEdphpYlYC EQAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/spacer.gif R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAQAICRAEAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/misc/arrowTtrim.gif R0lGODlhBAAJAIABAGZmZv///yH5BAEAAAEALAAAAAAEAAkAAAIKjAMHidsLm2HHFAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/toc/free.gif R0lGODlhIAAHAIABANYTNP///yH5BAEAAAEALAAAAAAgAAcAQAIjjI+pqwDpTAzzVPjQ3Nl2Boah Q0pkd2YpVq1mW2IypZ5vVQAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/misc/permissions.gif R0lGODlhZQAPAMQAACkpqSAgg/Hx+YeHz8nJ6ff3/ENDs9bW7nJyxqys3Zqa1+Hh87y85Orq9/// /1tbvf7+//z8/gAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5BAAA AAAALAAAAABlAA8AQAX/oOMEZGmeaKqubOu+qBgAdPMABUEDBl3shsYOICAOjgjAYTAkNgmMI3Og UzKLzsGB9jgIkgaGIOEsU8vY8HhHAhZ6B4ijoAA0mLtFHcCoPvE7WDhNhIWGh4iIbUMGCzkEDV+J k5SVlpdNizsDBUsDDAUMmKOkpZOaAj0Qe0M/NGdNCToMoktNBUcMCwAPDQYIQgOpSgwGdMAAWgAI OgRJbwxkWHdBSRAIyDhhZDSaREkPfQoGBgI3QF4FDWACAgVJCQznNII7BwUFZLC2WEXK5QJsKCkg 4AoNBPi2oKFxryAbGTAiSpxIUaKIEYQUECCQoIepjyBJBcC4Q8GbJgsUsQJxVGCBxybYmkBol48U LET1MGmKNvDGgDq9gAgpSYOAgCoRXAVaCkCBAJfLvDyQNcZoEgTcjDpr+jSJwkYC9hw4sI6GU6jd ZtCj4QAQ02RV2hU5urGIrSERNmZdsDECXIYGs2xhBqjm2kFNdfTzwY2NWgCymkLgezTZrjzchBGz bKVJTgVCjP3tvFhZAjIaH+wqV+bkgTqLVfMQ5A1BBLcPDIfczdvQyMdApPQeTvxhCAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/toc_arrowprev.gif R0lGODlhCQAIAKIAAP////8zAP9OIv+tmf+7qgAAAAAAAAAAACH5BAAAAAAALAAAAAAJAAgAAAMU CLowwk2EsNycgMiLI6fVBjIWVCUAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/toc_arrownext.gif R0lGODlhCQAIAKIAAP////8zAP/k3f9pRP+FZv+giP/x7gAAACH5BAAAAAAALAAAAAAJAAgAAAMX OCTQPiEsB2CUrN5LjOXMNzXQ6BQZBSQAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/rarrow.gif R0lGODlhCgAVAKIAAP///2MxnDExY1JSe0pKc3tKpXNKpVpahCH5BAAAAAAALAAAAAAKABUAQAMx CLpMIS+M5eBsktEILTgaA4ZKlWFdNJleeZJwcYVGyxTpDNTcifcWXk7xs+2MRB0jAQA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/uarrow.gif R0lGODlhCwAJAKIAAP///2MxnDExY87O3pyctefn7wAAAAAAACH5BAAAAAAALAAAAAALAAkAQAMX CLrcziOIQB4oLs5NrY1Vo0kdMHITkQAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/dot.gif R0lGODlhCwAJAIAAAP///0JCSiH5BAAAAAAALAAAAAALAAkAQAIMhI+pGb2PWoC0yooKADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/toc/darrow.gif R0lGODlhCwAJAKIAAP///zExY2MxnLWczt7O5wAAAAAAAAAAACH5BAAAAAAALAAAAAALAAkAQAMW CLrcriQISce7cdrbMp0a9AUbE5VAAgA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/math/12pt/normal/alpha.gif R0lGODlhCAAHAPAAAP///wAAACH5BAEAAAAALAAAAAAIAAcAAAIMRG6Rxu0KXnyqMrQKADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/math/12pt/normal/beta.gif R0lGODlhBgAOAPAAAP///wAAACH5BAEAAAAALAAAAAAGAA4AAAIRRB6WuqDO3DEQwVdbjFbT6xUA Ow== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/ref-arrow.gif R0lGODdhCAAHAIAAAP///wAAACwAAAAACAAHAEACDISPoYGgDc+TaxpbAAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/math/12pt/normal/scr/minus.gif R0lGODlhCQAEAIAAAAAAAP///yH5BAEAAAEALAAAAAAJAAQAAAIHDI4Qy+0PCwA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209001.gif R0lGODdhyACEAOcAAAAAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeX l5WVlZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXd3d3V1dXNzc3Fx cW9vb21tbWtra2lpaWdnZ2VlZWNjY2FhYV9fX11dXVtbW1lZWVdXV1VVVVNTU1FRUU9PT01NTf7+ /ktLS/z8/ElJSfr6+kdHR/j4+EVFRfb29kNDQ/T09EFBQfLy8j8/P/Dw8D09Pe7u7js7O+zs7Dk5 Oerq6jc3N+jo6DU1Nebm5jMzM+Tk5DExMeLi4i8vL+Dg4C0tLd7e3isrK9zc3CkpKdra2icnJ9jY 2CUlJdbW1iMjI9TU1CEhIdLS0h8fH9DQ0B0dHc7OzhsbG8zMzBkZGcrKyhcXF8jIyBUVFcbGxhMT E8TExBEREcLCwg8PD8DAwA0NDb6+vgsLC7y8vAkJCbq6uri4uAUFBba2tgMDA7S0tAEBAbKysrCw sK6urqysrKqqqqioqKampqSkpKKioqCgoJ6enpycnJqampiYmJaWlpSUlJKSkpCQkI6OjoyMjIqK ioiIiIaGhoSEhIKCgoCAgH5+fnx8fHp6enh4eHZ2dnR0dHJycnBwcG5ubmxsbGpqamhoaGZmZmRk ZGJiYmBgYF5eXlxcXFpaWlhYWFZWVlRUVFJSUlBQUE5OTv///0xMTP39/UpKSvv7+0hISPn5+UZG Rvf390RERPX19UJCQvPz80BAQPHx8T4+Pu/v7zw8PO3t7To6Ouvr6zg4OOnp6TY2Nufn5zQ0NOXl 5TIyMuPj4zAwMOHh4S4uLt/f3ywsLN3d3SoqKtvb2ygoKNnZ2SYmJtfX1yQkJNXV1SIiItPT0yAg INHR0R4eHs/PzxwcHM3NzcvLyxgYGMnJyRYWFsfHxxQUFMXFxRISEsPDwxAQEMHBwQ4ODr+/vwwM DL29vQoKCru7u7m5ube3twQEBLW1tQICArOzswAAAAAAAAAAAAAAACwAAAAAyACEAEAI/wBlCRxI sKDBgwgTKlzIsKHDhw5tyWEGsaLFixgzaoQ4YhoPR4V0EUhHUFoBbLK85FEBxYq9FN4yEmoSKYOX jThz6tx5kNaoFR1k5Ys3UAgVadKkKFUKralTKFCdOWE2lQkTJViVINvKFRmSr2CNGTMylhgxXAMX IElHjqfbt3AhoglwL889XwMp0BIIxxpCXRAeQYKW8B41hEIubJJyUMJAXqFewBDlI67ly3F1TJL1 gAhmgmKo4ZAFBpoOaJygyCLSzjNBPC9Y5ftMu2GAEBwS0EbTp169duvguHED552de/sE1ZNz796e AHmi27MT752adfGKy2nHXbgaNGiEt/97Vw8Pne7G7bBJ5yZduXJozrExU04cGHDevIHzwk0MF27/ WUEDQ4jckwkk9diRRwKN2KNABJRgw8okbAQgUAGEQOHJJkrQ4sEFFhojRQhG2JCJFw/g4QMSRAhR W07KYIGFNuCQo0Y69QhQyCB7KBgPG/G48Z0Z7plhYztqsDHPO27Mk906aKTDxjnrpHMdG1Wew56U wLG3DpZYvtMOe2iQcU45bqxzZjngcKGFNVQ0pAEDDchCAg7MFIJCAyDIEoI1ncgyySAY5AGCBXtQ wYkswIASAg6BXFIIB3AQccoIioihgDCm2PLip6CGKuqopJZqqkM+9GJBB+Ic9E4fcCj/4gxBTFhI jSGy0KAAB4p4Co0Gm7zzEA0PsDEgQbQ0BYU01FABDRRUWEMNUlZQIQUVVFhBjYzYaKGNFthgYwUW 3IBLDTXYTBstFc0uda0USTnTlBRQNCWNM8xaoU0td7yRxhddbFFFM1FcAwEyyhDjEBNUaOMQL8YI BEQ5ZlQmCxbvgXPqxhx37PHHIIfsEAhipHAYQRJcwIQM0shSzicd1CkLJR+MEJNDuiSkgzDAACGE EMIQQ4QwQrQozNFHD01Ei2aZdbRYRAgtzNJTD23E0MRMLTTWxIgllhFIEPMVE2EXPRpO+TRwCjgW 2LOOJouoAAElfkoxihKeIMMLD6Gg//UyF5a0g4ka92BgwU3cXIDNBgQg0I4CIp9Kw14H2SDQsZ8J Yww2dJDhMhzlWAGFDmTpcg80FK2mhEBa4IGG5dYEsI4uLcsCjS66YBOKNRFH7vvvoGI+EBGSSLAA Wp/RYAstNthiA/O0RA999DbYQMP1k0c/+fO0XK999rQ43/2Ak9NQPfPiY+99927Fg00eBBiDhjdw BKJEOXvsQcQKC3gjhkCLAAQYPrAJJ5ADE4dABA/IQAZM+EIHIKACJtqxj3gsAHgFoQUObIELHOBA Fx30IA46aIsRbtAWJTQhDmyACxKi0HkorJ4Mmcc96DUvhTI0n/O2pxMccAACA6DFCP/2QoZIiIAR m5DFBrTwCVk0oA+BaKA9iCGEAphBFpFolRZOEQkyWAKDYLwIG0jhgdSF8YwYWYcyZPEOdlHgEJ4S yCAaQQgfECASCeDBHyaRCCQgggkZwYU90EjIgVjMIBSw3DpqMZuD2IIAVlgBSQ7ShzK4ASGNyOIV C0KDSAyEB21BAATMWEgM6kIEwBCIBS4pEMvFhRuXAIQsuHAYz9DCB7bwBiApJwtGEEYWyohAKYdJ zFLWgwJ28AACCKKJA/hgF1yQBQcqsYcCALMGeHDAzQgihK0oQRlMcIIznPECeuTiESghSD0MEYBJ oGMO8IRnHeYpD3iUYRlziIM85FH/B3r4sw7wgEc+40DQgsYBHgd9g0D5WQd5wJOfZXhGPBs6z4Y6 tBlrgEc/6bFPesyzDIcghzi4ILyEHKWYKE2pSlfK0lw5Qwzt4GVD2hEDbqjgEAIRBhpcJBBskOFs GrEFu6TBLnhJwxracha8qGEFaWjLGki1Bhak5dSmTgsaTD2KNKBB1HGKs15Q8GpUnOCEqECDXdZA RBNgUIIPkIAFNSjGGOjRAWYkzCEacAAniCECaDgBD4g4ASQSAAgGsJMJnbAHIvCgAgYAQgLnkIUh ShEIITgAHKNYhDgGcIoTUGEQ2igAIsLoAx7oghe64IEvcOcLH5SWB6jdW2p54QMh/wAjaEPzARB8 oVrX+sIXqPUBL3SgA9wVF7U8MC0PdJBcHbh2b8k9bc+Gizvl8iCFMlVIJAoxikFYgAuDsEJmNUAB IxjgHQh4QB5GK4t97KMgZpDZIVQhTSC09L74ze/GOPiQnAmEdHsBgmtkgYxdTo0WvOApRFDhhOwm xL8C4YGDFeIEHiCEF8QgCxGMoAysGENoYEPGh4mBDBB/RQlMcEbCmAENJYgFCWJRBhS8cogBYAFb 1uBq7OyABAbcoAEE2AcbwMANMhSAE+kwghGAqhFneOMDyECLD3CBBFnQggf23Qc5lOE5WcjhA4aA gCUasYhEMEEDgIiANUSxDzNAAP8CGhCHEsTBBv3a+c54Vmku5ACMG8xKFk6ggi6YcQJZdMKazksJ DGRRgkXIYg8u0AIhXJQCQnBhHgUhBiQkEIlOT4ACFAAFAEZ9g/8VhIUjXG4LQ+hCXBC3g64mLg9w YQvd6sDVHWShLnSAAy9ggwhACDYwjACFQNQ5Et3gQAMSEI92CAADyxhDO67HEzyoQQcDsZ5BsI0Q JvMCIb6gRBzzbCpDNAMCGPALudeNE1rcAw3sxqAH1tEBGEDiFLJQAygG0o5K3MARjg7FAyRhJzBs JB1k/HO8F95f9jL8UzTwhDN0AIpcrGMgBDfVBAZSARbUYhaiIMrDa2ODjUdCGAX/mYArK9HIg9jB E6s7yCoscQMMlFQgu3hEIRbFSU8KpBJA0MU6eEG3kdemE2SoRy1isc0KTPhTKhcILjoxgxhoAnlG pw0WADFt2nBCCIgIABIU4YJ0IIEEG9AFGjKhiILEwwSiMEEKLJT1z6DiFcOQgQsU/rEGWIIRMFDA JutO+I0ckiG0wLptZWELYlhYFjaAwmh4IAwLC8GVEBFEJcThAjkwARtGkAUGTDCJEFiYEiS4BCpk QYwYEMACg2eII0BhBswPZB4VpEMEfvhmR0Bg05aAwSYcEIxcbEIDGaAEBjLhgRyowBEtWIYrUqEC U6jCBa9oxjJCEYwvLOEJzZhC/zay0Q12JOMG8mBHF6LQi6q/4hfm6IYmMgEKAwSCAIlghAIUIIFB nEMc4KANT0cQvLIBYsAJYBAApYAIoXABTnAAgOAAgBAPlOADviAIbScLHtAObmAJcoABqLEPmiAQ GCAGFEAAleALGWBwYEQFIpUOlQALMXADtfACoqAJFWBEF2AITVAEISACH2AJkQAJF3AL3ZAJwTAH YzANxbAMV1AMN9CDC9AJqYAJkSAJmgAKJNAJHpAACNAKJrABljABDKAIjyABmVABgeAJLcAJmHAJ mIAJklABJuAIaiAOvnZzBiEOg4AACoMDOiAElWELwkADwJAAQkAGroEJCEAJhP9AAgNgCdpQD5FA CALwB5bQB1gACgeQAdxWeMDjDMYADvewNGzwDt6gDIQRJ9bwDlDwbbIgDaNBC2wgBw4jC24gCFiA BMggEA4jDSKGDFTQi6BYjMZ4jMiYjB5jA06gDM1oV1DABMrgjMrgDMzgDFLgDGAFBU7gV1JhFeLE DNIojSgmjcqABFixFR1mDFzBi+rYjkqAjkhwDp4QCYyACAxyAZ+gCjfQCFejYAuBBp+YEExABLow SVLAAY4wAH9wAQ6QB7JAABAwAc7QCIoQAHJgAZBwE9x0CzhAAzeAcsYgAqUgBcpwC8bgAK6AiyVA N2jQCyPACgIxAUNAAazQKjX/0DLjNhC+kA99kA9AmT/3sAB+oAfNkAG/BHlSYAXVAi9nhQ1atS3N 0izjAlVMKS5UMFXnwi7TQlRSQA3ZyBRcxY3aKAVclRTQIC9QsJTUYA3c4AL0EAfuYFDu4A53AAvO oAQK0xDrMAAmoAjrgA12YAgEEABmQBVmYASQQAYixwxyIBDt8AAJ4DnxwAgRoA14sBdiAAa6MABU wAViUA8Dghe+gwvV0lROtZXwEpVwwlREpS9ewAXagAXdAgZQaQVOSVTOspZ+hZZchS/QwBRJgS32 YpbaAAZuIi7jQg1N4QRb0TsMQQGIkALehQ2AAAwLIAmMwAGP4AFqoAqKIAcL/xA1gQAJ85AJRtCL 5AABsiAAB2AEj1ACCZBKyrhuTlWf+Jmf+rmfeTZhUPAHAcAYn2ELe8MLyHVawmWgBgpbrvVcFkhb wOUDPZOgpQVdCFpazAVdssUDpZVaHFqhu2WgvjCActEHl8AIkwAFizAPixAJZtAJEEAI+RAM5FAI qWQDoqADFnABjyALmBgoOuALhcIL2JAJyNAJ64AADpBOC6EKPhAIJCALQuAMKDcJD4ANNeAZKfAA XkAHF3MLPOAEVUYQuMAIlDAJFZCmlFAJG+AOozYNA1AQPGAWQ+NkymAEGUYWMJY1KCZiSiZiSgCV xOAFamAFz+Ji6OgN0uAEIP8AAgHABmJQLmAwD5eQAMiQAb3AARmgAZNACRowClHwBg4ADETAZBuh BrQBDq1yRnMaNHj6NUqGNR+mOWUhNvDIYWL6FXjaNUywFdjABU7gYuxoDEpABdjgBNLgDeLoYVsh L8YwNTuZEfuQAPuWABYCCJEAChgABgMwCArABeCAAd4qCCZACMhQCYBUCSHABlLQAW5wCnigBBXw ASeAA54gBosAYfy5r/zar/76rwArECwQApyQASVFBKBADiawPLwlC9xQC+9QAvdgO6lQATAwK41A AhjAAA+BdQdBAx6EaytUQiVEayJEsjFkQrawayt0Q9WzQTawa81jAycUayv/6wMgtGq8hgu8gAvR sxMZwAAHgAN9Yw2ZIAEbgAFAwAB0MAnQsAePYAZgwAiKEHqc4AvMsAETkA/GIAr5YAkW9gF2AApQ 0AG8wAmf2ApSMGFMQAp6+BaqkRDKk2o7K0K4lkIjBEM84EHLc7cxhEIwm7fccz7Vs7K6sEG31kI8 ADQ4wD46oQYM8Aj24AO0iQvvIAc8UA5yAAbO0ArtIAYxtwHekAAZqAyb0AdG0Cq+4AX1EbCmQgOH xwM3R5oMsSBv67oQoQyPEAylUDu4i1LkEAqLkAFa8Lv3FanGuxOHgGnzgKoMIQGAJAuOcDIYQQwP 0AsqcIvJixMaYAITkAgI/8AJCRACdGcLE0AAqkAOKkAIx6AGKmAAy1C8GEEGorAIlrBN27sRIZAO TDAOgXUOFuAAEjMLBrADAhAK3DAMf0AK2lAE4mCup6ox+UtMwBACE4wQUGAAOQMN0QsywmB7F8xN XyQJgAAHcDAQHBABDcAIDdDCK+x7DyAYEcBpEzABkcBpkJDDERABj9DDPvzDgdHDOxwJEyAJkjAJ l3AJA+EAQHAPXhrCBQEMFqYL+UCfspBIsuAMjMB3BdEHlGAAt5sPMWcQNnAAkYAFBtFJA+EMeIAH xhG3UEwDjhCRe4lxriQJ75UQYmAKxFgQ4nABHsBKBqECjaAAVjwQtOBz0v97CLxwChmQcVAsCywA AkVQCh6wRgIhCa6ECX9wYa9ABlCgrwOhBNKACgeAEB1wAHAQCmnsGAKxwqb1AAIcybKgA7xgC5BK EHphKpAgPOAgwbRMBF80D+LgBnQnCwxAohshOgyRCK4UKa1VibQsC4JQC6LQCiEQrXAhSqmQB9Bw CCKABQrAHGzwCJMwSATxCIwwD/OgABZAyzRwEx6LGYXwCKgQD3jgCaVwwh7gSeJwCCRQUv83zf9l AT5QCdDweKIiBl2GEAxABT5QdNMMDOeIFcpMKuCQAZdwARpQDwT90b5jB4MwD+fABdggLVYgVdoA VVwwVaqqBu2w0nBiLdT/sCzpAgXWkBTdyI1klZbyUlT1Qi/ByY3ceBVY0WHKgDDxGI9kUWJhczUN AW+QhywFAQfgxJF2gAmMMAiR0AARcA9CYAGIIAFQ8AGEUA6L4AiWECcVkdT8NRCZ0AhC8AsCag+C QJ/OcAB4oM0XAQ5yMBzpIAfvAAd0MA95sAd/YAiKIAh9gAgGkAd9sA99EACBsA8F0Ad0MAAQGAh7 ANl/EAgIQAiZ3QCFgACIkNZUSwmGcABoJ7T7gAcJsg+QkCJ/TTFoYAZmwEDkIAZeAA5goAUXvQkt TAOigAs+kA8S8AEb4AUK0AePoAXrUAmJoAiFkAIMYLSAdAElYAZawAHk/7AKBiANlkACpAAEFAAM GnBxDMEKFlILxjAIGmAHspABHbClAtEDmfAAGwcHMokQBEABnXaFkzDgWQAAANAMkEMQBGAIfeAA 2/AG4RAG4dAN3/ANYTAGdXAFsLBPbYAOZ1AG4xAOayAP7lAFb0BP+1RR+8QODkVR9QRPAdUGAZXi 8+RRGvUEXQAP1xAF0xAGYbAF26AOQdAHZiAG2nC7A2ENB4AJgKAEMzIPm4sNg1aQgyAtAqEEv0QO AmAP9lUOhbAPwiDBXuALwEAOSOAMVMCCDHFbsmBfA2EFFMEFLYMLhcAItaMNEWAACs0Q3IC/BIEN cCAHAnAD6DB+yxAMu/9wCzMQC1cQC6NQl2MwBmFwBcuQDFfADvAQDeYQUPDwBm9AUDKuDqzQBONQ BccQBMcwBVdwDVlgCpnQDVVQDEfwAzewA8FQDFswBJbwDOzwBVlwDV/wBVVwDeiQC/dABmBw5Gsu NA3hC67kA1DgIkbgDP4VI5OjBE6gC8DADBctMlLg2+UQAAcgShhQ7pHQCAmQAAWQBxcgAYZgAAVQ CIIACIIAAZ0gCBZwCptQCZJAARfQCAtAtXaNAPvwBwNAAARQAAYwAPeQD4rACAdQAH/wB/sgAIBA CIGAB4ewAJUtAAlv8YVgDyLlBViA5K9sCCbQCAYADh6gAJfABqHgAJT/kA5FEA+IwA264CFWoAAX sAGyYAWd4Ak4CwQG0ABM4AuiAA0gIAzSYAxWYKphRG2Tk7clNEPjMz7rQ0PRszzSI0Mz6zzPQ7Mw 9Dwv9EJ8Kz7LM7PTgz0NgQkLEArxoAlU8AoVAAIOkAmy8AHOMALcYAFtIQsFRGCngAYSgAeGkAhi AAqIIACygAMhAAwgcPFSoAnQCdKWf/mYn/mav/mc3/me//kNYfIKQTkyBWGOyxNKcIWGwNc8IVTn QlTMspZI0ZXRMlXYcGPscvs5XfvVolWwH5zwYpbamJbP8iz1EpzG/9NHMQhL4Aql4AkgYAIv0Ath oA+dYBVjyhB9oAYN/8AA6QAGe5APDIAkDNAI1BAKo8AFnSwL52AJOhAKlKILHIAAmEALWOEJRGAL hlAIbJABsvDBAIFLFrAkFjZskpUQB46EYOZ5cUPLBi8dstjEYIMCjyxpKiy0YiJrESkMDhKeRJlS lg0I52iltEHFihUq0qhAoUZNmk0pNmlKs6LFmpWcWKzJpCJTmpSkSXdKgyZFChQozpxBowpFCrWp TrJCk4ZFi5ZJ6qo9Cdbs25k1b+6ccqLMiEq6sjQs0iAslBUwoRKkiKCGTaMBBpx8YGJFjiZdsirU Q8IhHycfERxsYIgAUQNBG4A9CCDLRzI4cGIxlMXLF8dePB5x4CELh/8NWXBWyWJRQBYBVVwKCZGV qoA2Oyp95NmTXPm9RHzwJbMk7SQtrVFrQoNGjSbTmdy1j8WCbaw1a1iwWAmPZau0nFCZSsGKHVpN +PKhLHUW1pq3InXixIEHnjnmkEcePVhwgglj6qLLCjYYhDBCCXkxoSIJL8Qww5NsgYoK7ZhijxoP oYiKPfW2skYbbLgQyjzzZqJJJ6Ck2qm++KojESrspHEmKa0OISETSRIgJJA93mmnHWmQQWLBC8UZ gBIwcPBBOifAocGInWjB4B5nuEnoDwrmQUgWKxYIAQwlXhJCGGYs1DBOOTPEISdqrNlKKg/LE5Eo D2eiQgtuuODGGxX/seHmKKKsYI+KqZaiUaqowJoqKvjupMJSD8/zED5JqXBCCbkwxISRCGQRARlZ hFHEkg80MQaReyyBgo0JBijAgBDqEeKABWhBAxLRRLkADVCAmDNZZZdltllnGeQFFyO8WWhBUH3w QRZdcKABHGEak0UHcDdcjYoKyJGFiGfXZbddd9+FN15556W3XnvvxTdfffflt19//wU4YIEHJrhg gw9GOGGFF2Z4YSi4WCkhGmTbMN16bDhHIFk8QeSCPUBIgBIiAHkEEjcUmGQQMD5woAEbpCmHlwux yQcCZFGawIRAalAmIR7mOsmI2JzlQRghjhYmaSKIEWbpptsUhpil/6UmhmoihFHCiKalbhoYpasm ok2mgeFaGCOMYJoII64mBhkjhFjaFmfzaYQUWw4RxAZvBmGlEU94EAEbTWThoB5JzjnFgT5slQUc EjSQZQFCLKGEDW1WOMWNPB7JA5wLVQnkEjBkGQQEQWSBYJZdHkiIFVIkgcEWbWZJV10MWVBlD+BS 4uHqo68mAnipr97amLONIcYIJJCQ2ghkjHG76qqNaZIYZ5gx/vjplUAGCy+YYUJUJpiAxp4EsGhT 7maNseKEAebRIR0u/liHGiwal8UON7igDX9ZgABEPrCxqgEYQgrYQJYvIAYGBjBCCkOLUCsCsYjR oeQe95CFIjaiBf9QfIIQCWFAKAKnEiAcDWlRQ0IPonCJcqwGJb0DGxPA4ITqEQMJomIaM7BnDB4i QRnMUIMXhCGHQFgHe0pwhjigYYVkLMESiUCAIOxAAA5sI1UrAEAbwvGNI7iiBkMIwxwcsDTUMEsH voDChWxxMxtgRxa+oIYSEsILbxBDFkqgAjJ0IAVhyAkaE/sXL5aGPBsi4WzSUx7VkmcE41HPGMpw GzOcoDzjBc8YWTMGOMTBBEgy6YbW4IYSwJCHTDlDCaJSBhTAAQW0qY9ZbugDKhhwCWZUYgKPOAAD LJAJcphCA+k4hA1skQ9GUMMDmXCCLDagAQwCwwkjkAYPKkAHB+D/QRJ0EFbDJGYDiUhEmNy0hQ1o 4E0a4AAXNkCnLdSJA13owhY8EAIudIALXOBAnfPEgRbA4It60hMXukCGF3hgDC0AgQezESYOeOAL HNACkM3qgyFY4IYNkCMCrTCECChBhUAUBhHtoEBC+oCIhHBgAICABDg0AQ4P4AFysrgAFhohAE4g 4QK202ZOdZoSNzx0pz8FalCFOlSiFtWoR0VqUpW6VKY21alPhRcZLgQcJVghIWJwgAKsAAhEHAAJ shCEA/YhDAccAg32YAQBaGOE/iVEF0SwRl3SEQhE+BQMM6AGCRiREGKwAWiy8IIZNNYsG9RTXLrA 50IUawt5Ktac//aspy3miYt12tMWiuWBLuhpWcbqQAfs5MW2NrsQedqCFi95VgYagAkzcIAaYBCA BCoBgj1YgqLl2Mcj3pEORWygAXmwRGw2EAopcKNzqkAAEzxwAU0o4QN5CM1JcjHAWVAhXJPohDeQ kQpAWMIIYBgBJnCBjV5sQgYJccQvGnGC0c3AGRFLSTsRO1lcMOMIJIBDGVFCi3rigL72XOxoLUva yD42suFkrDp5kVnKmlMHPAAGEHCAhX1IQxlKCB4SoNCOQCCBm+sSgCJEMYF31KMPlVBAIQbACztw AZt0oENC7OCNhESAAQ6whi8gwQBJcCG6iMDFPAbwASxg8CQ5AP8FKBKgEia4gg0OsONJiBCIOx4g IYTQxAIY4gwMaGIdKkGnMCvrjG78AgLYcOV0KKsLXyDWn/Scp2Tf7E9dUGSNQuBBninLWB58lhvY IIIP8qwaI5DBGjbIQwbmIQ4xYMMaZPiDB1LhDRr4lFnYkAOYIhQbaUS5HQgIhMx4EABFHOLLdUlz QpjR1pTQIpkAo8Fl++tYAKtT1gd2p60f+0102jPMpwV2N71pa3V+07+4qLSllWWLDTQiA/GYQHmg IQAQEKIF7wiFF1YADUbswQ7auIQhImEPe0DMETTOhBcIwYhUUIOo5bzsZR2rzgJzFp+2tsFCEIzv MKeTm9z0Jjg8w4nObtKA4LRItbJsoIA/aGAC9phHO9hwCUmQWhaJMEIECECAAUaujyghRFxlcQI4 QEMBUEU5u2QmoYAAADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209002.gif R0lGODdhlQDIAOcAAAAAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeX l5WVlZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXd3d3V1dXNzc3Fx cW9vb21tbWtra2lpaWdnZ2VlZWNjY2FhYV9fX1tbW1lZWVdXV1VVVVNTU1FRUU1NTf7+/ktLS/z8 /Pr6+kdHR/j4+Pb29kNDQ/T09PLy8j8/P/Dw8O7u7js7O+zs7Dk5Oerq6jc3N+jo6DU1Nebm5jMz M+Tk5DExMeLi4uDg4C0tLd7e3isrK9zc3CkpKdra2icnJ9jY2CUlJdbW1iMjI9TU1CEhIdLS0h8f H9DQ0B0dHc7OzhsbG8zMzBkZGcrKysjIyBUVFcbGxhMTE8TExBEREcLCwg8PD8DAwA0NDb6+vgsL C7y8vAkJCbq6ugcHB7i4uAUFBba2trS0tLKysrCwsK6urqysrKqqqqioqKampqSkpKKioqCgoJ6e npycnJqampiYmJaWlpSUlJKSkpCQkI6OjoyMjIqKioiIiIaGhoSEhIKCgoCAgH5+fnx8fHp6enh4 eHZ2dnR0dHJycnBwcG5ubmxsbGpqamhoaGZmZmRkZGJiYmBgYF5eXlxcXFpaWlhYWFZWVlRUVFBQ UE5OTv///0xMTP39/UpKSvv7+0hISPn5+ff390RERPX19UJCQvPz80BAQPHx8T4+Pu/v7zw8PO3t 7To6Ouvr6zg4OOnp6TY2Nufn5zQ0NOXl5TIyMuPj4+Hh4S4uLt/f3ywsLN3d3SoqKtvb2ygoKNnZ 2dfX1yQkJNXV1SIiItPT0yAgINHR0R4eHs/PzxwcHM3NzRoaGsvLyxgYGMnJyRYWFsfHxxQUFMXF xRISEsPDw8HBwQ4ODr+/vwwMDL29vQoKCru7uwgICLm5uQYGBre3twQEBLW1tQICArOzswAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAlQDIAEAI/wBRCRxI sKDBgwgTKkzY5MqrHc+ICTRSLRaOKcpkDHzlSqAqHAtDihxJsqRJk0AEvioYLs+APARc4hmAB6Ye lzQF3LkjoCbOlz/xCLXjKA2YT01OKl3KdGmsLVumLTHYy8HBaxe2pCwoRF0hg3wCQFDStKzZsyHV VULhYQ/ahTemvJ1rUAwZOGoGmvnVy44qAwyqocrjgFxBGbES65jF+AMoPEQK3vBBZ9CiESxcjCJT AxCoUDFYrChVohcQDixgpHpBChSCG8hG2EiSzJkwKJZcwQO2DJgtX0N8tSDSMWEPZAtjCYzVZNcN JUJQ0VAmhMawYLGU1KLLvbv37+DDi/8fj3DWLfIIa2ypMoxIsGHElhhbsmQYsgCNPlyy1OmEHmNK KDPNNttEM0UTRABBRBNTVBGFMldsYUwvw0zRxRbZfKMGOtdEdtAveijCTh1amdGAHBAQQA4j4dhB jBAFoHPAFdERIIQS6jTRByG9oOfjj0AGKdAOWTSzRDBCBIOMDqiQsYcaAehhB5RwoOLDN0sIIYQR RiAxjAwy3PDKKzrcwMoNs6Ciyi63sELDDbHUskQNCfWinEYa0SCQRlPooIRG3xDgjhp5sNNLF3bA ocwe22SThzuv+BCMkAupQoMqmFqqUS2z1ODKDTWc2SYqrLhpKQ001KAKKjKo0uqlmsr/0Iwxr4Rq 6SusJMTGAX3IYQYfhyhyADPqXNPAMwjkcosDN6DywDQCkPHHFhD40aMg1xiQwBRuUertt+DORcQB Hsh1Eh67hKsuWtO4c9I3FtCx7rxMiSEIMuJEQC94XTgihCZIzAvHFvAgRxINhVzCDJP7NmxQGDVM VVKaJq3kML2zPAFSd10Mc3HF4NUyYBVN/BJMLzjUQMOZOOBgkSs1LKjEzELU4oqlbqJ6KayZ9izS MHgMAo8532xTAAEKFHCHAg10kwURV+zhRiHwoKJABUb0goQiyAxDSB1iGJGLMvv6wAxGSiChdiw1 wKnD27Po4AorscSNw5hmqsIKzKjm/4wpqq7+LZIOUWyjDhJZCPDNFU/soMQT31ShUeOoNAGHGKwM Awc5SwSs3RPIBGMM2R+XDp44BlxDEA5uXKFOrgJd84gSmQhkxh3n5UIAHLAv1faYseiwwyw33LDL FGjwhIcBxNxATBbPMBPFE00gsYMOPeygGGNy49BDLcO/nfIrsVh8UB8TiIFAFk+sqEAfCagxQTB/ iNPFBPDIkQAqT0hihhJiAAQCgvGAB6CjGkS4A8NMdzGNEMSBCZGBOYzBwAoKaQcYQEIFXNGFA+yC GR6ogAFQsQdLoEMdqAABk/QkkC/Agx10oIM75DCIMnAhBVsoyJiAZxGLjGkxOwiiDv+CZ5GWuext Q0xM8JC4g1rcwgc+6EEudtGLXmhJS7mIIkKE4Ic6MMMHyNhCM4ywAyDEghnN8NCkUKGMbUxlGOKI AhFW4jFirO88BxHDABygunnlAhACScABEoAGZSDCDBEQQDQGwooG/IIZhOhDFYyACOVYcF7bKcje EHKLHkTwIMO7ZJCEwIEKSIId3YkCAiDgCnSYYRbIwAERogGHjTEwDAs4AB7n8gox1W0WPbhFLcqH g1kMbxa1qEUPygfEIHLvFThYTA8Xo4No3gIIQIAiNm+Bg2aVBw3scMc0rpEFdpABDQH4hgAmEA2y LQEB3aCAAWbhhz9MYxdLOMQwmoD/gMu5whWWFCWlXNGEabABCVGgQxiYsYQbBAMJ3XjCqoaxA1Qg gRxfoAER2PCNYfzCorMAUC+UIDGBmtQk1fDAA8iRi+jcQB1XCIArdlGFWBCDBH+AABs/wIhBoAIB CTBAuhRCjGcYRAbBQBIQqEiELl2nqcaIAjKMwYxoZKMZfBnGMIxABNMA4RZgXeouxrpUbC7VikIg glp34YMt3mER7lBHF+DHgDr44A7NOAAacogEdKACCA5AAxuaoYcAhNNK6GjGHcwwhTqs6qSQjaxk 51KLRvggA67IAjxqsQVILOAPqOhDB9AhDlR8YBZuIggbYkKAAhQgDxqYwxtIYa6B/6iiFsKLWyx6 gAMZqCEcwVDGNb4QjV2RjxnKCMYvkHGFKlTjBrf9xS6y6QOTzW0Js4qCGMQhDgRQMCHEiEZHWtU7 lRykdzdgIUGekY3Juve98I3sFlbABgGcJA+TAIR64yukcFyCEyEAbUn0thX+UgodEiFheRfiCkUI wgKeFGUt9sAHMlCqACToxg3qoBBl7HcpQFiggc8SETF0oI8DKUAYDjIBN3iMIM7zQx8MIgQMfEFf I55LDXJRi1x4k7IVrcEtZJUHgfxiwevSwDQWUIAa7EI5lNiFB57QAxK4AZVyeADjCPINOKDjy+pQ yzu0UIkeFYQYwDjHGs5QhjKMw/8b6ghEOdpwjjaUYw1xeEQ0tFCOcozDz+WYwSvU8AEJ0GEaYTgA Ip6ACiFsIwvMgAMiGtDWSvXAzAmxpA6ecAtXECMlqqCOKpBgBBxoJ8eoTnUFCwBBb33qbi4L3g1c UQtlVGEK0dhCFnx8CyNMtwnM2MUs/hnr4NUiip8S3g56AMVY/LN44B1AE1ghg47UQiM6kAESqmBF VPRCEHfoAiqCgYBCXAFPNDCfqtctnsDBSmeuApO8XxXvedt73phqVc8yVSqdlWqLC9HIVrQrBGN0 bNzfOFkYmqCEL+RCOvTaoRFjfcS3JaZlRVTiEoc4xCM20Yk+yMVXc/GLpnKp5L//yEWEDeKHQyi2 ClXIAwYKkYUGhAMdXdDDAMjQCHRcgQCouMMGfvENNiQiHEZwxAWMsYBu5BAhAhjAvnJBgWZEIBBk MwQDnkEmPRjACKxoExACIQGQ/EECSbmkERJxCyF0YOXsjrtJBGAMApChDnSSe8PMEQx3wH0gBEwI tgzSjUaMsCCJcAfp9G6SOnThGngIRN4ZP69pAEEJSEaLH9jhgCYkQgM1CIcjUPEMChiV8qgvyx3C 0AcxDOMORmhAB0QwDGagQAIYCMYGnrENkQjAHRSDcS2qYI4BMC0CE3hGXMjwhW2QIRxscIMPahGN bjz/G9G4AjHqFowmPEgJTQ0x/xCy0I0uTOPm7GBDLX5skFzsYRHmyMM06mkIPvSCANFAgBnEIANi cFgIDyAG7FANd1AHd4AH3kYH2SAA4lAF7rIu0KQDTnQLWXQLs/AK5gE+ycQpLSOB3GNMs+AywOQD uyAEu3AyyJQkSKBWv0BqO6BuBUEEgIAI1YAATQAPDoA+csAOz6IH1zANXncHfcAMqEABf0ADXYAG E6AMWWaDTXANUZB6UjiFVIh6NWAGbOAhb1EDzIAMKYdN0zVduSByVGRFvaBWRLALYwgEWeQDT9RJ YBWHTwRFcEiB2CRyX4UQPsAGeRAA2VB+dsAG7JAHbIAHhjANzeAKTwBPiEAAOP/gB4PQDEAQDIcQ DEqwAG4gDnHzcALRDSLAAH4lEMGgAF9gCC+GCkqwP2zXC4mgAIKhDhCwAJWGCjXQDFXQDLYIc5RA BZzgDsXBKmljgk2FBEpADE1gDMFwBR0wA7QwBExABdSwCl/ADHLQB36AAHcgDmJADLlADNcQBt2Q DdcgBm7QDLtgDGpAB2ygDgUgCIMgB5hmEDUgYgihXrPAQmJiS1VoFrWwDXVgB9NQDUJQgGZQDbXw DFvABt2QK1swVAKRDeeBDgHQC1ewjxZ5kRgZWWQgQwTRBZKQBSEgEMxABrlyhdPQFDSgLD0Qgt4D EgGgf3nwAAuQB47AATXQA2T/MA1RMAXdAAcPEAE7QAO18FVx+AvDUAM1oAxIECq5QFJo8HcEIQeA YA7MMACuQAeGYAiAgAzwUAA9EAjiYA5+wADIUAfPoAOGEAix0AB28ADEwA6LAAhdUAdyMIsHoQOE 8GEH8Yuu0GpKESqe8myqMgxIEExj2ANC0Awpw4HQZBGdpjfPNms3kDI1QAxEsAOwdgM9AIMEgQzu sADhEAvh8A1fYATksA3NAAnMIG6ogAhVgAgP0AQDQAcHQAzKoABmIAQREA6BcAVoIAYZSSm78FjB WZzGGXFwsAEmUFvHSR6sQAZSNxJVYQIQIAIF1pwmcQtfQBKzYA6PQAYWYATY/1kSZIAEXGcSsQcB DLBG4ykSXcAO0ZAJEuCX7ckdWRAI8KCXCxEIIGAI+lmfBuEDcgAH7MCaIjELg7AAHKAC7FdB0yAJ YkAJjLYuuyAH6qBQAHoWdGAaH4AAqMBZWZAF07AF1fCezgAMHBCFjvYFX3ANLtoFMOqiLvoF2RAG YUAgYfACXvACA0CcGAkBHPAJF/ANBKEKgbBi8igEjzB5tvMBeVEQxsAIVUCPxRkIuaAKxrA/Gdod BnALfECfZnENalAHuXYIfdAEimAHRjAI5rCl3gKmhzEQoUIqxbFJHyEDqEISSDALAYUKlkBKRsUG g8BhswAIg0CECqEKTFoQu/9gCmOADVZgBVQgDUdQDWTgC7oACz/wA8CQBF4EDeVwBmeQBmOgDZrA CkTADL9wCxaBPTcgAzXQS59CPj66RepwAXewDWJQEwNADjtADsawB90gEUIgGD6QAOiwBb8QE2RQ WrVABkYAB9PQBObwn5QiAKcQA55AAqBwCiQQDERAAZYgCROwAIHQAE1wAwWACH7gDugAB4GADjSA A7uwma6AgTtQAzJwJnPjCi4DpwSxBH8wAd2wB1cgAIawB4pwB3AwAVfABwbSBzWRAFNRAYAgA9Hw DYfQBDSkAKMzDVXgpiI7siSLHulWTXByPW7yCrfQC1mUTWYCTObRSdqzNx3/B2tvY7NxU021kioq kxAOqRCVhgxdkAtIEA3iSQTZoCXVMDPVUFEFwQG30AhPsAUVVQVNlwhCQAzZgAPV0AjsgAioQACR gAbtNQlI4BwD0QR5sBM8IQACcAwAIAUKcJdq01Wi0wzAVAp2dg5vUA7rIAKs0AneQAVMwAQ/EAQb cAO3wAwI4gMUMgVP4Ao64FTEoARkhJT/BLR+QAdRAATKUA1TEAw6AAQ4ED1m9mJTIAZT0QTikFwd IRHI8ETDkEnrgpTFk7uUWTyN6TKzVkxJlBhmEquymo+14q8dKE2TeTcJoQARYAR5IDnZwAcZ0ABC 8AdicJp4gA7fkAjPAAR1/1kFAYAKcGABZvAAJZu+6oudWSAHhjEQzzAJZEAJApGYAzEFZLEUYzJx LdNLxgtNGOdDeAPA/Nu/SoREytZEweSGY4gQfSABZHAAWUAM6mABf8Ar5oAIRLAAOYkIeCCWqGAM HaAGRGAGBwAIwcAAEYAOifK+5bEIUIknGvEK4ikQvbBLCWGXMJaPE/dDwbQL7HANbpg9uyVyV8SG vQA+xJC2WmKUTxAFPiAGFwAIBbAHBtAHETAIl4kQv6AGnGgQlLsDbYUDdiAHT8AO5KAMNYAO8GAE 0YcM7MAOKXFt7GZvgbNveAynSPkLPqAKQFBqHdERwVAL+GhkayQEzBCrAv8BEj2gB31aQVNrDg+Q AHygAG6gDBHgBupgB4DwBcR5CIEgEHIQCSZFAyBQArUKLrcwCe5wC35ANg+wdVsgAXpQCM/QBA5A DHaACJPwDakJygLVCI4AAjiGSQLRA+whikLsbLYVYb0wVD6QeRczC1uxffNCA/+ElNocKqyAlKXS b4CTKfdmb6jQDJJADlQqhVkwAnyACvCwqOOsb3icKTpTz998z6XSDCLgDkIAsIy3BWSgCocweuvb FMrgA0t5EDl1EL3QBxCwSAbBAEBXENMwCAXAmRgJB5FgAo9wBwaxC1ZhEKzAB91gELPQARLAAX5p CQJwCAFznD0QDbtAAXL/YBAaBUrZIAZBuxHxKBA0YA4V2Zx1UAXYrACL+hYGOp460AwvzR3HMgiv wA6RsAsMoAdNAAjzlNFIEABQiRa3EAa9oApZgAy6IW5LkAUZeQNNsATIoIUFPWB/szLdzAr07G+l Etf1HM7hfCqw8s0rw82ukhCsUMMIAU3HhgqzYAfooAzsIA7GcAPoQAfRag5NwA7mEHwh8YsCAQHk wAegFQ12kC5VcAeLpxT+SyZ1cz13Qz5FtBh8Opl1Q03iI4J8esDR1ANjhYcqVz510gAQ8AoPoANV QACPcAjPwAC/dQ0EAA/w4gZdUGQF0Ai5YA5qoAisawGIQCxREJ3pUQKx/4ABRbsNPUAIcADeYYAJ ZLBQGFAD0UEQuRAA8N0TAzAAQZAOwqAAreYKyHACQcAE1AAGY3AGDVADmnAMR8AETgAFzuALytAE rVAMTkAFTsADsMAIN9AMnAADPBAENiAKpPAArsAHwMAEvKALxSAFzsADSqDZBqEDBWAENKADr2C6 gextOPBYDnRNAoHQqQVxr7Ay6cwU/kwQ0txLcZILREAMS1wLOFALRrBPM0MMRlA+QoAMT2AM3ocM u+AywVAF3WAG6BAOctAFpWsGgSgGZhAO4UDmDUoQr/AFhVBTRPDEr6AEUxAL6zMFegIP7oAADQAP pEUA4PgNCRAF7GAHgf+A2euCKsgbTcHjCth8NzyMA6Vyr3gjJnOzN+TTRDtwCzrgKWK8kkH0RJCe EL8gCIdABAywBBIgCAm7C+6QB/xEMnrgBqygDuEQc4CABBb9znIQAAlgB8wgAMz51sZ+7Mie7Mq+ 7KUjA2mIW3AjTQfMGIxxTBqnREa0v/0LTQCs7S5zRPoIY00NStr0oQdgB9EwAIk1C/84DEOjDL+3 08fMnglhDB4QBh+gJxTpQLOyFDRQHy47VlpSRSW4JUgQDE5VH0IgVnc4h3EIRRVIh3OIh2TV1agw DIJACKxg1FmgBxjwAE+A3OE4AAFgBovwDc8AdHuAAb2gyYkgBkpgAab/ZwfIcAADEQ7zdAh0UADk mwi9IAKoEA0G0AtNUAkQAFoDEAJfhgoesB3E6Qq6SiAE8gUmwA2p4Ac/hlTBEIZp5VSkNgwZiwZQ ggCGAA/EIDrKgAz1wSVquAtEcPC/EPdKpTWXSwzGgAxdc5061MqkogpQOxA2Y9JQOws94kAakSv7 OhDdwAAJNhBvgikHoREzNRC5oOgH0bI2bQzEUEW/QFLG8ASgEwxiAAvgMGd3lga6QAZVcACN4AGX cAh7IAfIkAtPYA4CoAfusPMQEAa5wAx74AAJ4ACQYAKdEAjtbRCvMH8PFwvV5kmu4Elo8AtNsCro UAB9kBJbgAgDUMPY/yzN4MIKzYAMQiByRBD3aFiCwxAFuFgF4ogEL9tVZDV9oy5yWURF04fkwzAf dx8FS4DDBKEEADHoQQ1COFwRePCAz68ABIAk2Jatj55dxMKg2jMMVQNCbOqgAhlS5EiSJU2eRJlS 5UqWLV2aFEKOxkuaNW3exJlT506ePX3+BBpU6FCiRY0eRZpU6VKmTZ0aZZXT1chZ8OooCRqLGTIl RHIRIVYLFaBHehZRwtAgBCVWwe5cUxZFjBs8d3CwqpULSC8fOoD8YlXDGBAarmr93Rbr5DU3BwY8 60amTzdAeqpBEofOh6sC4hBIqJLrgSBXwcgEQuKuzp9wdvDIQIkDg/8eO6iemMERbRMiP6jChLAw CBWEAQF6iFRFQ7lyVcwwubtFkgaQWz1qxcJxS4cMOwSufNPDR4ChSDd8qCFzpRo7c30u7KAx7EuU J0+aNPtyg5WbP1WWuFlAAQ+qOKmaASIgIAs1ADHADjWEyIYcN+i4ARVykEDlmwLcIUYNdvpAYwtU tlmCnAHgEGMHlGaRZAsBYAOpCQFQIcSvQgC5AhU1CllAxZBkUCW55Z7ApI5cSnqlhhteYTKWGlRR 5olbctllFyCU2AaHGnzYAYdXcIhlllyerKEGV25YEjtWaNhhh1pqmUVLHxQzaZYnMDRppl1AmsaM X5rpZgnb1DCCmG//mpALCFRqWKnCpc6E1JVXXKHBGCVq8SGXW2rZJYpYWNkhTjBjiaUHSpU8c1JX tKzhm2lywc5LIGY5CY4EBOhGHWXgeSSBO/hAYxBiBHEjjAoCMKM3ZTa4Bhk1GCjAiAkqMOMAdcx4 KlucdKjliSpkUOYZJW5xBb4mlogOlT1RQaYLRYMRw4hcZiIClV8AiQIHbfflt19//wU4YIEHJrhg gw9GOKRrBki44Zq6IMWcO2yKBUaHD/bhIpZ2YEMcN9CY6WKCZ8GjAxKIcakWBWgooBmRC85Fj0my aCmYQiCwoIGpXibYmC9equUQZQZ5gmeBVUGFBh1ekgEQDzB4xeiA/+WIAo9fXnoljwEw6UXqgHfp 4Yp6vSZ7ACGIESIPWsn2mg4KCBGCpuPY9jcKC8LZIwGXgjkAFQKUoZtfOhI5QIFFkGaplmb2AFxk IBpYQA6AgchggZrIoEREkbPIZIENEO+XDgcoYOSblnzAZJG3Gb24Gkme6GAap2Q4EhU6A3+ZgVkg uAYeVHwgQwwxIiODDAGOaUUCrIgwoxsxtgkjmy+uoZ76Lqj/YvprulBBlwy+sBj3nly5vaQu1sap imfE/6kAV/IgCQgPGh+JDUEUCB8kQX4mKY8GNGafT3KRhWZcoXYhIUA2SmIEB+ApJEjgQASEM5It mAAPCAjgTxpQi/87mKM3IjGCWEhSDXN0I3+ooFJJruCQDPrkGR+4gAeQ0cKGmcMVBAKKDviQAWRc wQ9XCIMQvmCMPnSBhjZpgAg+QQk2/KQXClCEMfiAiBk9Ahk4EEAgjniwWIBuiy+JhRGWMIxfEOEX u7gBDZSEpiW9ghWs8IFXcpELOLkiSDRITh5VIQM+BqmPXjzJDpYAKlS8QgZikcHSkBEFIhyHCH84 ESDkIAYl5AEeUVgAHJ4RiALM0CYUYMAh0PcTNEwCEg8IRAIOAJ1YEHAK1fhCZOYUARBswBGRiAAg sqAKM9VgTcvZY5CEqZyVKIMQDKjBA1gRDgRk4AFEaIA6uvANOrj/gQwRaEYUGJaACRBDDgQ4RBSG QYFDhIEAyPgDSgJhBj70IRiHQAMqSFAJSKCCCC8IRAhoQIA97MAHIgnGEogx0DEqgAcVuEbIRBIN aLShDeeA6BvWYAcJxOEcb3hDOs7RjkiEowzlAGkb1tCGHMRCDiB4ABqiMAU0BCAYv5uCEoIxBTWo Y5QnoQH4fjQSQJYkKjW5RReicA2R5GgYTUCFMvBAM1SwQQBdQ4kSDABVktRAEtBYhi5wcQQq4KIK 33DGGc6ADS1ogRoGAIIuxgCNYhTjCNBIQQ2IkB4j+EAIU9hCD1QRi14AoQfDmEYUdrYiMTRAsL9Y QhNcYQRk3AAB/8xwGSryYAcFNMAOdCCDHsKBhm4EIhp00EMD5iawJezhDwGAAzqq6QPzEIEIfvWB D5K0A+rogEk6SGMNXqEfGgTmSTLoLR5V8caVIKMBhhACA4ZhiEI8wABLqIMBfhGIKiijD26ogTuy MYU9MIAIhNDDHVzxzQXA4wp3qMYX1bte9rbXve+Fb3zlO1+v7cIBCiBqUJQUCx3oYBZ1dIUObjGM JSzBUjt4xV96EYxgGIEIt3hFqeDU3//u4AaxiG0PehAqHNwAB7Y9yTSUEQZl9KKHBvzCFohRAWOs DxUPiAYEBqGMAqDBD95CABqAwAAxAAIV4btEFhpRDT68VA+BQP8GCFDRBQLU4hkpoMTE2KAJRRwC FY3g7E1JYgFEKKOnqLhBLW7hgynt4hfYIQQtgCEFK2DBGitzgChEsAFIJIKK//2FEHowizFT5wZ+ yUWGu2QmNJ3kABHYhh/69ABGCGILdDDDIJagACX84gHRcUATUIuAKEhAAU+QQSAkcwAjDGJpqLhE BD4iElKlMSRGUINkbYsABUQBFdEYRB/KV5IKTIAZPx1JLIDg1x74YMEdXoAsgsADXRQhCQjYZwgW AQEQUGIQ5LhwL4Tggx6YmRlPWNUujGAEJViqFq6AFEqM4BJWDNYVfHRYu9HEJCaVCd2SYpKXahCL Ns3Cvwg2E5P/5o0DfeM7wv41SBtP4o4H7KEAz4iGMfSwBwP0gQACmMA1wkCEKwTiG0+lQTMkV4BZ BOAQ+SVYct7oW1esybdmQncNCjOpMpmJFckp0xvtLfN2o3ve+nGFL0/yDXYURxnNIMMe7iCOWYSD b2JghrrIIJJhKHAXG3iFOui7da533etfB3vYxU6TGoThGwfsSb51gB1SxYLeXsr3qOj9drjHneBt 7y9/ZzGLHRS7B9WJrUmqMQUxVIEIUbhCFnbxhWoQoxFNiAZICDGN5jIjD2zww30K4IZf8JgBT7hG OFByAwsUgGG7eEINpoAJPkQAFcyYhCJ8jIAFJGBdJmGFABwo/xK6s73DHm773XXgJbiPqu2+J3h/ 3RSqvo95jnP0ARDQLpI+RAANfOhCOB6QiAV8QQ5oUC4gvNIARQniCR1MwBQOcYCoK0AiBKhCH04Y kllw4BkNAPYTEqCKRtQCCRXoAxEJAB45oFioDg3blCwIAhQYAEX5EbsbFS8plVsQgjBgBk2Bk1gQ s2LLlOq4Bb6rklvos14Yt1yIAnLIhi6YhmjIgjD4AiAQoZIYLZ/oBYU6iekrioG7O4L7Ev+qhWEQ gv5aO/5yk1qwDjfRDgMUwUzZhQVTglxoAmsKAzH4hm8Qh3DYBS0DiW0gBD9wAyTAAzqowgEwA3i4 gGiYAlRQgnRAyAYKQIAeSABA2AYgMIIIcLBCUIMAQIM6KJp+kYG5y7dYiUCCayM0ITjjQ75/Q8Al 7AEgIIJegMRIJIJdSBeSuANAEAAEmAIMAARDKAAhgL8ECAdxuIFhYBgdKIRvCIAtKIBvOsUCyIIA eCxzGLtHEYmAAAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209003.gif R0lGODdhqwDIAOcAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeXl5WV lZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXd3d3V1dXNzc3FxcW9v b21tbWtra2lpaWdnZ2VlZWNjY2FhYV9fX11dXVtbW1lZWVdXV1VVVVNTU1FRUU9PT01NTf7+/ktL S/z8/ElJSfr6+kdHR/j4+EVFRfb29kNDQ/T09EFBQfLy8j8/P/Dw8D09Pe7u7js7O+zs7Dk5Oerq 6jc3N+jo6DU1Nebm5jMzM+Tk5OLi4uDg4C0tLd7e3isrK9zc3Nra2icnJ9jY2NbW1tTU1CEhIdLS 0tDQ0M7OzszMzMrKysjIyMbGxsTExMLCwg8PD8DAwL6+vry8vLq6uri4uLa2trS0tLKysrCwsK6u rqysrKqqqqioqKampqSkpKKioqCgoJ6enpycnJqampiYmJaWlpSUlJKSkpCQkI6OjoyMjIqKioiI iIaGhoSEhIKCgoCAgH5+fnx8fHp6enh4eHZ2dnR0dHJycnBwcG5ubmxsbGpqamhoaGZmZmRkZGJi YmBgYF5eXlxcXFpaWlhYWFZWVlRUVFJSUlBQUE5OTv///0xMTP39/UpKSvv7+0hISPn5+UZGRvf3 90RERPX19UJCQvPz80BAQPHx8T4+Pu/v7zw8PO3t7To6Ouvr6zg4OOnp6TY2Nufn5zQ0NOXl5TIy MuPj4zAwMOHh4S4uLt/f3ywsLN3d3SoqKtvb2ygoKNnZ2dfX1yQkJNXV1dPT0yAgINHR0c/Pz83N zcvLy8nJycfHxxQUFMXFxcPDw8HBwb+/v729vbu7u7m5ube3t7W1tbOzswAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAqwDIAEAI/wA9CRxI sKDBgwgTKlzIsKHDhxAjSvQkwUMPT6b6KDoIB4NCEEMmihxJsqRJhQ/CCDQkIxMNGjA6zJDoIcnJ mzhz6iS4x4zAL488qTllicNEQ1F2Kl3KtOEdawVnjjQErKnVq00PaBvYTJibO3fi3JAYiArWsxOn tOJlLcYPtAgEEDQlQ8UIDTkkEkKGtu/CGjaeHXxACOuAAQRhUQqA7QQviRaW+Z1McFEghytUMh0w h2ASRw6+RJZY4QvlvmdoiCyC4+1ONAoKJkFg4IlCU7IO9hFz2iosIEtuYoukE00egbRO8qnWW+kl A0wZdT4ZJkJOB9ma36SDAu0MGsRKMv+jQHACH1pTNHWR2GCrdonVGH3h0mzFDsrENkmVuOVCQVQD mCJSHYi9txAoJbAgioEG2XGIRMRoUJAWrkQ0QwOFYDCJGwwO5AENqnT4UApkPBRFBgNxEcAcmZhg gmQRCUBHb3wIYZOIJAHSjEBFoJgQL4gUBAcIHCByjERqMGDVEijgwEAnIYgwQgoL4tjXEhsR1AYM KaAgjERkKEmSKBTcwqGVaAokS5YDGaINHtLscZAvnxDQgVEFiTGBQtYkIFAOkYyV5qAIubJIQcVI EokiNxKaphwssPACm46KJIsJnUQyhUhLoAFMA3g40MBjE9HygBaSiCACJNh0yMstIFD/QAEYOPZw BRfLaEFSNMbggEkLXpDESjTTkEEGqZW+F4kApBwTQxATsWLJIdpoIwENyoy0RAcrYBIJG8mGaxAW Honr1xRBmttUDRpEMgJiDpxAgiBHCJQADJkwMIMyl0BywhkG7QEHQVOAUOVVoqBCCwo/7CCgQcVU QAYKEKhr8UimZOPGEkEMcZ9EidR78cgD7VGiJ4eMgcAMgdA6kQdNkCwzAwB7Isofo8BggwjBSbRB UjKPjMcaBP3QwRpj6XJARIdYEXRJU1QwUCFfYjUHAATtMMILRRRShESDFPO0SK4AoQtBnHBx1htt EATKIT5IskheEWWwxdgQrVCAQk3Y//AwUwIMjBMG6+GtUAONRFTAoUutMd1AZWgSSh0HPwSIy4YT hMUrqJT0SNs6YSPmQFd48Qwz0Wx60BOZDJRDAHG8cQLmeN8wSuE47YCDLTiJgcdBX5TAW0QQpIG3 BoNc9cUlJ33BB0HFqLDGEYaQIlEeashsBg6U9bHnSFz8IdAQEQhhCSEfdAA0RHRgLS4pKuiwSAge NBLIfpOxoFlEyAhCkC6YoMEoEFEDibzhTGhiRCboRqgkfOJjDolQQbLhC0/cABVewB9D2rC09/wh FbAImgBI4JAnFKIg0eCAK7KhOogA4HFW6YINLrCBEWAicwOZgSp2qApQKEQXhiiILf8aMYk8FDAi 2GiATn7ggVUwB4c5SQLj/pQDUzhMgw2ZhpwiogAm3AGKfSlCugYCi05kwQ4IMUAIPDGEUnzNEz8o Aixg4QRgEMMXUZiCL4QBDGDk0QkC8MATmhAFXzwhClQopDB48QRfOIGQTtAFLx7ZBCfYghe88IIj dIGLQS4BF0mwRRKSQItRmnKUtCjlEWRxhFU+wQRLkMUc51gEOQ7hlrOEhSt2OQRX3DIIwPzBIM7A ih/8gBXI5KEqevCDHjhzmT3YoTOdaQpTrMEP1bTiDnJAClOQgps5YGBfbhCBEQCCFSSRAyfoQAcE nG0kcFiASWawhS5oQRnMYMaRSBL/BwjAIQHK6ACOcFkEKmDxIW+AIUl6kIlF/OEPghkJBE/SDOuk CQKXYEQJPPA3iaDCClioEEmWYQkadKITD/Dhe7hgFGFYYghaSJ6IWIBOT1DCaRI5wghKMIkSRIIS tIMIMzzgCQvMiBYsAKOBrFAuhezHhzWYASigCooaRHUGoshqVklBihtUsZumyAEqvIkKZ6ICFTsw KyqWaUy2/iAIxxzCD1ThiiDskhW0LMIR5MjKvdaylbRY5ShlEdgkLOEIqLRFCpU6EVN0Ig5gKGAK YCQJaRwCADXAxiq8MA0RNGEJM7BGIiTQA2JAIQSWCEZILsEJEUhBDliZwjKoIQNn/3ChaoxlLCtk gQVnYEEWNTUIKSwwgr9FwRAa0AAOPlCIQhCCEBlARCEyoAFCIAIDhoDuc5+LgeQiNwOB0EAhLFAI Q0zXu9oV7yAEMQFBNDcQgxgEIAIhiAsEAhCEqK8g6ksBPwiCAoGwQCD88Ic+VOAPE/iDH/pbYAdQ oA8QMA8E+uAAPvjBDxHuwwMgsAc+8IHDEtDDAx7gAAfkgQF7uAMD8oCHO+RhAQtQQB0SYIcEzLgN dagDAnaMADocQA4HOMAlnCGQSSBDFazYwRBaMFGB/IAYVrBCowjCgZDkNk0PiIZAUHCkD0BFJDW5 cpoacLKBCMMPL3CESiHigZ6JGf9Hd7gGQUhxhhK8AI0SKQQu3mwlBhjPE5UI4ROCUwKcQqQDTuAz jvCQHZwUItGK7pAC3DOQILjBEhrA7UMO0cJIDwQUXAhDNMCghYMq5WoEwQARNpAITIQwIoUwi6cJ 8gQfeSIRsr4KAkAnkBrQwRcpeJ5DavCEKQApPLMWSBNa8UYMfA8rcuC1J1RBiQ58gBAddUgh+DLr HaxinwMphg1MrZMBINATOTiEDMKQgc7V7W6ehsGfD6KJoCplANARyAJKoINLVIIGTW7IIHSl6BEc ZyEKmOJSBgBbnFQgWG++QBAd4oRRWG8pbuigJ6wBATswIAJ0CDhDKEDkKxegdRL/OcGXd5INPxGE CowAwY4kAoiIKrUZOBDURAQACaVgA8+eIAUr1FBMOLwaIoHQMhh5IYTgjkQVNhAZTrDxOzL6xxMO gLdBgOEGGBwEAtOAIipeAe6TMELaJiGDEiUyhVAcJA9PNFwM5LwTM1ACJ3EaCDUk8QibS4QPK3+a wZuyg1G8syTRsOhN8NCqp0EgcVi5gB5M0gXxDcQE1uiAHR5RhutlT2Zv4IRftkADcjekGZcZiBto kABBcEKkEMmD+y7WDNWc5gUwmsgyLCCQOiShGk3INvtmLy5qrN0TinD3ZPZQmIlwofkDQQUKnA6R BMglWTOYks4N5IQYHBEixfDf/0ASATpDEEAiBTg3mkKQgu1bSQXSiAgxbH0SN5zfSh8YBbTCZQCi PkQYE5cYIFAFh1AVEDEAcdAhiHAKsKcutoADIdIQwCAhA1EAwbAClSAJthERcNBwvREBPvBGQfME qVAIBDAA3IYQvOB/A4EIYMAJL6B0EPEGMzIZdxALyZE5g5AGokAKxAACP5QIBaEI1VBPrgERavBF WGEGDiAQM+AB4jRrS7ABBeFcfGAACtUQalB1OxEEj6ADppFsC7EEHzAQTnAAJZABCKAJgecQ1TA6 JXEDhFALjSaGDyELZYgT0zB5IvEATFCDdigSsDBFogALtCAHYXAMFwcRYiBsCP8xA7TwBI8EB7PA B6YXiBAxBIxQEENQBMCgCzlYEIhANJ6wAiU3EF5wcAhRBi4nCiQQhVcxE6AwEzNgVaJgVZ6AVdx0 A2H1TeGECl+FVs7kMKawVqpgTDmwA82EZMcEC3a1S7DQS7lUBK4gC9Q4BLIgC0MAC7KQBEdgC0uw BLYAjpx0BMUQFOPjBc0QB3IwB9lyEDtwDVonEcpAfyRxBApHElrzfSXhB35HEmUACBNhBw+wBQhm UDkxDWywkATQBj7BIFogAJyRaxMxAyBwhCahDKBwBm1wiX5RA0klECywZyIhBr9ACH4gAZ0mEU7g AYrAARsQdgzSBNSwKfPIICD/QA3FCIsRcQYxtgDrMxFd0AokMAIk0HgTQQI+wFOPYAIb4JELMQeH oAEdMDwMcgfDwAgcgCnKJxELwAjUYA1lkBsjEQZ+gCNFMABtkA2HEQDI1iGWEIGYyBBUYAeyNgVo gCMNgAkJEAIhAJUGoQyZQCpDoAh1IBJegCcCoQuWwCBngAUC4QwfgHbvcQPHUAS8cHTNkQ0cQAV0 8AKLIHVzuRCmAAghUAjIohBY8CAFQQYkaRK+wDsCQQz8WClUoJiOcgXiN5oGcSLiYgu6EEmYVEnB iQuRpAtN0AS6sASlFI7jGEq2kErRWUpFIEu3xFe6tI2+BExDgEx1NVc7tAPK/9QwxegwO0CM2cRN pAAKonADXZVVN1ADojBVVTWL9blmgDlrpGACPiQJ1UAC+2QJYnAI4DIQ2NBUBVEAFCAJJ9MDlVAH QMibTWEKG3CEhLAJKxACQBMBm2AJlVAEzcCFA1EDGfAwVDAIAxB3hHB4TCEBmWAJmMACK3BCEmox olACCpEDgAAJfOB+NaodgPACl7AKl+ACLHgQGdCEAqEKzuAMXqAFzdAFXdAMVOoMUuoFXOAMy9AM TUqlX+AFXuCkYdCkXhANz1CmYGA6zyBqYeoMXxAGZboMpgMGzxANYSANeCoG0mCn0jANftqn01AN ZSCogkoNZmANZpCo1XANZv9QDYhqDddgDWiABtZgDWlwDdiADZgKAGmgBtiABtiQBtiQDWmQDQCw BgDgBqeqBgckAABQLQ3pBuYmAALwBtlAAAQAB3BQALr6BgYABwTABu6WAx0wCpIAA4uwfwVxA47Q BwlBCDz5o0rRAJoxCS0kCi+wiAMRCDRwAiYgTwaRCFYmrVYBASfzATawCTLACTaQCWv2EB4gmuS6 FA8gkwhwCo9wAtHaEIogm/PKFA/QeZ5gAs8ACxbQALI0EYkQiv+qFHnwkKJwnjNRBNHwrg7hAf7a sDvBAE+kCtowCTKwC3UYEYjwmhqrE3hQM0dgByrACDgQhhKhCKl5sjjBAHT/N2fL4Ab5ORCE4GY0 ixOMVmQ+wQB8cAQrUEFMM7M/axJB6wkR8Ai8oApHAAEsUJsNgQhIu7SLN7I1wAo++hA/o7U4kQAj axKGkLViWxJzMLI9YAhzMK4RsQErmbYiMQcFmiKFsAISgAgCu2maNmtOsAkWcAEWQAMxYzUBkDXM IBAF4LMOkQEUOWu+0FScdha7RhBlIAFfEA1wC7ZvmWxDkAsrwAKZ0AImmxW8xgxWMAAuNgCVoxBJ 8AGNgAiaYIBi+AEVMwOdEJRWMQfnNoF7AAEY8LkOMQhl52mDQIGeoAUyYLFMIQfXNxC+gA3OEHcQ gQFXIIYPsEYE4Qf2yBRu/5C4A2ELZzkSe5FsB3B3BqEJp9gUElkQVkAAz3CTj/uOkaYGmoAQUTAK zrsTAxC9nvAEGHAAxFABkAlrahNp0lB6CVEHAmUVb4AAA+EKuOAL7bSBEUEIBMdnWnAK+yoQl7A/ CwdDtDABNXADFcC7Apd7YjYFTccQvEADH2wSGTch+ZXAEUEB9KtUttAK8poQdDBG9ybBOGEBEHdl P7AKSqsQlJCXjZNvnlAGChAHCUAHbyB8DCEIMMtYOdAKG+wQRRAKWHwS2kDEAyEAlJCzEwEI7QtG M2ADMhkRA5CPOIEGgDhtI9AICzACS7wQgLDFYLQJxBcRlDBvOYEGQBd0RP8jCnkwZQ5Rc7mFAlkI Ea7AAz9sEmjggZ4AChYgCRxQAFbLEJfDWCPgiCNxDSRUHOAqFNgQCCcACR5AfQ0BCGWGQxuAoCQR AvdXx0oqEKRAAoCAUX3sBULQAl8Xf1AUAdx7EqqgfzlhDSJaAzFaAkagCOpnhvlrEA7Qt4ZDB+qL E9fQHThBBr0MEb6QzRhRByLGAjKINwCAcjrBCAl4E3knET9AigURAdz8NGEgA0uhO6c7EtJgUROQ Av8oERHQhjKjBTwwwyQhBpVAz4onEM/QCCeADf27EHug0CPzBD6AkUpxCHxYEmBgygURygvxFGNT BK8Q0DshCqFguyPxBQL/iRN5gJQkowqtYGgxZMziQR4DQQYKcAWloAEorRB5ULYWcwM6cMRYEQgm LRHMUNMCAQJ8oAmuEAI47RANoNTqQgM3ixYv8MUSwQVAPRDTEAgQQJYRgQeGbDEvsMt9QQWdsLMF wQW8NxAkMHMaQJkM0QCDnCxNYAEUcAqpoAB2fRN7kNe6x9ieUAMT0AmfYMYQYQd3Ky7WcHyKIHJY 8QL2GxFbIH4Z0AgsUAjaQKsi+BAJgM/hcgNptgXM8AwscBGUMQUy8LoOgQyOTQs5QNsTkQB+nSYz UAmW8LWnsQABCBFXAH0CgQox0LmqDcCE4ggocNS9UQn2xhDFIFM/AYS6/9AIyvoQcVEpI1AJ2ioi fYPbC0EMNCoQGHAcOQAJXr0QcCDdOAICl2DcHYIArPkQxJDcm2xJInEAe4Mm+efbjlIJtUyXyksS pcMFfSDXDOIBoyDLhLIEocDZByEMzO0JAhACd8CiDxEAEq4diMADDSgucfDADcELDe4JAfACGKAM XCACO/sGmtwcF7AK0G0uJ8DaCsEL9EcKD0ALQXAHGvcQAjDPzTEBOpDaI9MDnXDeKhiAoNAD06AL SQDSDgEHk4wWEOADDCszFsABCbAAhCCEPzJGtZiNVwDIDsEZp5EHq5CxTxMIMtkE/X0QTsDiAsEI +HUNq/wQA3CYWFEDV/+ABcoACMYwt0+jAJ+AApbACVeHELpAhQTBBR3QASGQvRGhBnfcFM+ghJ6A CA6dW7jg554ACHZApSmuhaTeFAaQDBUjECHQlVIoxJ6wBINABmGA61ooojsBAEpgAQsCC0mAC7aA 4MlmC/moAX9wsCXOEEmoFGiABNg2r7aQh8ubARBAAX8QATLtEGcAh2knBIwgl/NKC5tIEBuQG2kg 7A1BDbVeEs6gAyRwyeSKhwYhC1ZA5fP+ACRxDDhQCY57skWg5jcxDfUOEVYAA5rwt0tbBFPkBZVA CZAgCSXQzg4xDRPNEE2ACZ3g6XQrELAQoQPBAC7wBwlw2QTBDBxwBz7/6vEKEQ2dsAiMQALBgDsl PxCamCc20AomsMQS8D2hcLgDMdAKUQY1+MunTrOqQClCoQdlsAJxTBAaMM8usLie8ACpogKvgAkv 4AKboAkvQLoQvwqnYAIpIAm98AmbULowAPEx4AIwOPadkAku4AItQLouwAItQPah4AKZAAMuIPac IPZ6rwktkAmakAkxAAMxsAku8AKcwAmTzwk8AAObMPeaIAOf0AmRDwOfEAOdAAOhwAmfIAMyIPml 3wmtDwQ4AIMu0AmcIPqb8AJlHwOaoAmd/wKaAPEwMPYucAksoANhjwmYYPaYsAKZsAJ/D/2YPhBz EAeq0AAcLxA7kAIh/5AJof4QxUDVJQELLz4SpEDHIyEBbTwS1XDWDjEEYtAMdgABDODoJ8EKB2wS N/DZJcHTJSELAGHK00CCBQ0eNIhKFkKGBSssu7EGQkOKFS1exJhRY0ZXo5wRK/Zk40iKbVCUkCRi UA6SDR0kMoQhEAY8oFp6ujEnUCBCVG56+rJqQwZDYFrm8ICiVq0UKgr99PRsRTEfLw5AxXoQUYcw f1DUuLmATVZPwnQc0LZmCtmsukKd4tWIAFuykB5QIeCCZcspdhbgceDk6JUfzZx9AbOELlRsExaz nSEB6xFqUeYQKEBA8c8oZqyhiXJzCRZmzZY5uwIVFgA5CQoceww1Uf+VTzgi7SVJoFMEPhOK/VTD J2sAQXSphQKQJo2v2D8t3BhIIsnNJExaRJLE5WcZG3oc6GHWfKMvQ4Z6VdLQoZp4kmFeyLFG5sfP MxJsYhU2LEajENfY/wfQIAyAQOEEEHAbCZUmeAHGF4EChDBCqC4YRBktrJCwoh1UybCiIEL5gAbt qDmkQ4vSyEAB6FqawwZMNMFBEFFaOuIFa35A5YpFJDPRoCQ0acKTMyyxwJAeG7qEQ08qEWkkNCoo CJsOWkLlkgaOsaIaTOo4skuSqNgEh1DQuCmIPRppJBBevGSzxw3w8EQLTXrwcgkb8jhFBSz0AKFN PyvSQBFq9OCEzor/XHHGIFeYKOAZMA5biCRXZCgmCsEqsODPi3bAUNOGjiHEU02F4UBUhq4YxFQ/ qdBA1YOuyNRVL3EJVVaClpDBhElOSIGSEyYBVtcTUEBBEmBJOOHXEyKZRJJiIzHhVxRMkITaSCgp cNcTKll2EkoqIXaSFJp1NhJik03B2BMkocQEcychVpJe0+312xTGNQEFb1Pg9ltKKNm1kmsn0RWT AmwV9YYZEWZYvB5g4MIZHrowoY1j9GihhjJiSOIIEWzJhoQldDGUoB6YwAGsgSiAJoyGX2boBhsy GEGSG1DQzpMO4GCEGVX+8IMVMqCYpARbtqBDAIEaoSUbRgZiwzFNOY6AuWqCUMFkB4IqqcYWATYh BZsWYAGlhWesmfIgQ+yYQpgOHCjmBGCesGaTha3Gm6AZDvoBFlsDAgA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209004.gif R0lGODdhuQDIAOcAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeXl5WV lZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXd3d3V1dXNzc3FxcW9v b21tbWtra2lpaWdnZ2VlZWNjY2FhYV9fX11dXVtbW1lZWVdXV1VVVVNTU1FRUU9PT01NTf7+/ktL S/z8/ElJSfr6+kdHR/j4+EVFRfb29kNDQ/T09EFBQfLy8j8/P/Dw8D09Pe7u7js7O+zs7Dk5Oerq 6jc3N+jo6DU1Nebm5jMzM+Tk5DExMeLi4i8vL+Dg4C0tLd7e3isrK9zc3CkpKdra2icnJ9jY2CUl JdbW1tTU1NLS0tDQ0B0dHc7OzszMzMrKyhcXF8jIyBUVFcbGxsTExMLCwsDAwL6+vry8vLq6uri4 uLa2trS0tLKysrCwsK6urqysrKqqqqioqKampqSkpKKioqCgoJ6enpycnJqampiYmJaWlpSUlJKS kpCQkI6OjoyMjIqKioiIiIaGhoSEhIKCgoCAgH5+fnx8fHp6enh4eHZ2dnR0dHJycnBwcG5ubmxs bGpqamhoaGZmZmRkZGJiYmBgYF5eXlxcXFpaWlhYWFZWVlRUVFJSUlBQUE5OTv///0xMTP39/UpK Svv7+0hISPn5+UZGRvf390RERPX19UJCQvPz80BAQPHx8T4+Pu/v7zw8PO3t7To6Ouvr6zg4OOnp 6TY2Nufn5zQ0NOXl5ePj4zAwMOHh4S4uLt/f3ywsLN3d3SoqKtvb2ygoKNnZ2dfX19XV1dPT0yAg INHR0R4eHs/PzxwcHM3NzcvLy8nJyRYWFsfHx8XFxRISEsPDw8HBwQ4ODr+/v729vbu7u7m5ube3 t7W1tbOzswAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAuQDIAEAI/wBHCRxI sKBBgVdaHVzIsKHDhxAjSpxIsaJFhqVmCJyR5cfBJbIUXhxJsqTJkw0z8LGoESLIHShjypxJ02CG PjUHLhEiMqfPn0AbImLwcwmsVUGTKhV4SuCNmSp/9pKVY6nEIGmi/VC27UeSN76sLnymKaeilQX7 pFGjg1DJqanEUmw2Qm7BBhYWZsImMAsMTsYI0SDgzQeHqhCjDnwVq0cVYUeClIxi66ndhh+4Hfy0 Ra6DQwsrnTmowlpFxQN3kGo2aomNKySJ2Wp6mWEkNwdfZPGcaCGm0aPUmDioBkVE1AOjgdOBxwzt i8Rktax9MFKa3MvkKtCw0BLfUW1OHP/MluI40YHdDBRAYOACj1kEB5QQ+Y2SQD29Zxjw08BBH0RA UMcQJGoc5MJuYimQwUIlALeNcQahoUJEQxXUSgpDoDTFbAIeBMIa2GmHAYPfpSGeQdWUldh5AqXS 2CqvDPHKZLLU0KFBIXizGRfa9XZQgwKlYclB1ZSX2AMG9cEBG9FYNpIvssR1I0GRdJMbjwWVwsmM Oe2hSGhoBHnJQWdMSNArT9QBgy+5DIQIkj4BA4SNUw4EQoEGrdDZKHV0cNAfcMakx4I/mjZKGmMa ZIaRo3DSxUEwLANBAz8BI8RzDTmywEEnCCDQM0Is9McfE4HwRoij2OHIn4AINIQMNLj/AMqsoXxC igcT8cHdQZWUmGhBZmQyUCesGdTCFhJA8BMxPBSUQ08EedCqQSgU8KkOC1EQKESRfHNQJ9nx6adB EJA6ShKhIFXQMy5MtMAG3W0jUDYrHGQGhKO0IM1BnmzxgLk5NSFED6wgSNAtqGQ4igebGnTJHJ/C ImogE0Wio0GOCkTAqgb9QfG5Ljg5UDPtSqTHlwdRIu8oZ+BLUDWcDLTCvgapwIUDH+cE0is6JGPQ EDTUIpAj2w50Ah4CeSExqxOFgJtBnGncyEEOKDvKES2ILFAyLEykAK4HWbKyNScWRIaZo3RCxkEs iOHxSN5gIhAfI45CiCSPgPDIJWNQ/+IMCo980MEjjzhCCTOScMAIFDoMvoEjjDSSCBSiJLLIJV8o okEiiWSQgSIUoIIKIhMUUggFEhhigSCDSDDIBBT8IYgtJQACwR4PANJHA0ok0scfmrjSQAII7KFA Anq44IICeUTgxB54HIAA8XhYwMsd0eNhgHoF2FEHHQQUQEAdA5jgiRwBxCHAG98A8AYNibzRRgQ4 gNMGG990w802DqCCRjbZ4EEfzECGApoBDNXwAQIeUYilbEFuDdlD53QRiikspApEEMgDKjCSG5TA YAepAwpE4INfWOkgCpjaKETRi5FkQxIO2cEfJHCIXzRCMgeRBB1GAQxSiAUYDvGDDf8IYYRGGEMT AcgEASaAiFF0wRPJcMUhXgAHhnABhwapgTIYYohPdIAK35tEH0KRDE8QYxSC6EM2YsCBTxzBIW1q SC0wVZAbFKAAhJDAKLDhAL6IoQcCyc4UDICNUjRkBoj5SQ9kQYlGNOIRg3OEI0DQCA88ohGKgwTk PIDJRHBAA4pzBAcw4DkMaAARqLzAIQxxCCl8xyCzQMLpTEcIQlDgdYQoBCEiIAEJACIQEvgDAxzw gAX8rgHlYsAD+LOAPOihAQtQQB8iYAsuLSQUhzDAAQxAgPERYA4DmEMdxIk+AchBDgBwgzfCEQ43 tOEb32jD/eSZhjVsAxtpyGcguhb/FBJQIAsteEMIZtGIO9zADWZgBTFSIIwBeGIBFCiCDeLAiViU wAw/6MQ2VtCEQVigEJBohicgMgRSzKESZmDENEZBDBF8oBm94EYSHrCCQpwBGNMAogZ2gYldjOIN cjAATkaSC1CcQQQDEAEYRjEFSyQCG63gwhAKkII6SOMVwMgQHcBBCIgVoQLTsE+dOrSKFhYBDKVI xRtHUYNcnGIGIb1aIo9ABhKM4gZrLcUtBgIfinhEINYcBWISkItSqOEp08lSQ0ZAs4o4dBYgqMMM YgDEUYBiGQWAwQtiAINPuEIULghFC1pQqxZ4IgahbUEnXiCKT7wAFK51rQs84YIW/9S2E5/gxAta sALabkK3nFhBJ1jAghakwAXDZUFyV8DcFWhCEybYhHE3oQIVZEITzs2ECU5wCUtcgrsm8C4JvlsC E5CgEpdI7yQsYYISTGIEIpgEJSQhX0pMohIk+IAIRPAISIRAEv4FgSMs6QEPfMDAouTABk6ZCFKa MhGKuEAFDEGBCVQAmBEQxk92IYTAjvXDSckAi2piFHWB+MRAwcCIaVJiFLvYJ4pwQFFC8uKxPoMD m6BCIwghpZgkYsUz6QUP6FjjIpNEEUMdxQymUAVgbAEYXDCGIUcyBVlMGcXCyIOA/EAoh60UJcgR iB2QAAUbdPkiwqAFkTsEAs0YxP8TsBHLZxaSAkM9wxWkyLMoYkAKGZiCAsfZw7KAkNgptdlAyJAL AwzhGzEIZBvDUVQljoMWgcjhloF4wABiUZBEiAIFLyjCKBZggxd0oNACIQYR6DRWSKysIC1ItFj6 4COD/EYgahCWoiD4EAwk2SliHUUIfDYSYdQIxB/il6ytIsHuhGkU5LGXih7iu2hVohFM8EABYgAT KsMC1R3q1rdAqBQF1M0glng2oqQdkQv8miCpWDNFhOEDcAsoEmzYDLGtoodzF8QS2QhS2V6m64cU AmCj6IUHLnEAe1PkCbLQ2o0kke8376kgcc6JHhbRHUcfitcEMQOvV7BFg4AiC4T/QDhNgEEEiR/k FlvYQhaQQQxkJIMYwkCMF7TAAD40oA988MMDFCCKnEHE1QYKVwA48CeVm0QP8DqICQL+cXuVrQVL NYgLrhAISpGkxweJQssF0opZ/OAVs+j2QB4hY4cRIGILmYDVIhICcByE5AIZANM75geBNCEGRO5C C7wWdYNUguppiDSwCt6JZ2wmCxCYe02aQIsf+GDfA9kFKxTmiEoT5AQG+BQrFhIBr0cEEiAySCcQ VIC9F2SGAlnCC4isDH5GZFDdoTo2QD6QFA2kBWG4excgMC2dHUUV5B5FEVQh6oVFgFN3gPuf9CiR EITjICkoOQFUWBA/UD8JLmD1/0C4YHuI6MH1BTFB6ulFJNtzwuMF0UQzHFB8iwBCBpgQwZp38gpU YF4gtaAKa+UI7yYQmnAAAtEMzfInRvcQH9AGbBMuAgA2rzcIAgF+EtcMnTARerArBkECVJcNvCcQ 0rAJMvNlBaECzwAIz6cUyXABxiAAOHBlBhEN1OApDIEHNoAIqJB8EvEDI/ANbwALS8AQrcADFrgQ PxADfnAHGkCDc9EAtzAHMuAQCaANJXcQbYAKyxAAoWdkYDhWDrcUsfAJfbUQuRAClkAIAjAEH5AI hGAto6ADW9QDHOAJHxBHbHMdB1EEMSB+BHEGL5ACJLAN4LAJijAJu1ENOECCMP8QCogAiAXRA6HA aQyhAv9HECuwB2KABamDAUPAA0jSBdpggWEAAbUgAv6mKAMXhq74irAYiw2xA4l0SLIIFMSACHjQ K4wQCNfHCb2QCQ6gClCXDR2QBxkwDaVACQpwCZXgDZegByzgBYFAByzABSdAABmARQ4xBefTAV3A AgPQCBBAAXDQA50wAyAAAUugCXMAQ49ABx3gABkQCsGCBpuADSoAB5QAAmdgBokgAR0QBjVgBHlB EaVgCdDgLYLwAaXADTAgb7c4kShRAzvQA5JgB6MgAdyBBjCgNbegA1BIkRNpCA2TE70ABLVIkhOJ ZEUBBGrHkhOZASdJYj6wkjL/GYsiNmPQkpM6aXokBgQ96ZOviAF95xNLQAuARJQ0EQ2mcAm5oAE0 oAZzgANJiBKF4HksRgtDyZRguJNIqZJe6RPLMG0TIYk2oZUzARImVidLwAB2sARzAAFTEAYTgIK1 4QVoMxMu6RNNAAQudyPEoAcFcAd58DR2sQAn0AxgMA3SIA3PEA1OSXUnkQFAOQqvAAptMFKZEHxP IgRgB2LTUAICQo8LoQmGolhKNhE/RhCzUAtD8AO3MASWOBJPIASBSR08SFoyIAqiAAMuYAstJGdn RhCZgJenYAd9wASO4AfGwJpa+QqicAYlcAMn4HgjAQxqBmIhcCpat2xLAQi1/xZ/qUkQiICdrKkH NhF61WAJuQkRtymRtYF036loxTkQlwAc3BBsIecyKaGWmGkMCkMSGISWApJsUOODQNEAjHYQmQAc 3TCCo8AN/skQGSBoB9EF7xkRxGAE8nkZ9FkQUTNrKFMzX5YGpGkQ2GCWDdGXNSM0JUEMQjCSbHZC BeECmRgUe9BEUkcz22BXKMKiDJEINWkQk2CjvacDRxAHYoUH6DcQR8AKNHpvbiaiOQoUegAaP2IG QZKiwPIrDoEap7AAxeQffIAHSzkKq+AJn6AJLYAbcEADLXCVBSEbBkod4vZmGbcUesCj6IZ4iheI QroQKmYQZ8AKqKAKWkYSG//yoXYBCXx4o3uqFP3GIMBhIkRScA6BAZc5CsvQDeEgP21ZEVOwnR82 CXZnEC+QhUuhIM4WJBJaJBFxCL9WAlfQA5fwBD2AAgoaEcIABFOKp4hJEC7wKGLRgQthAnyYeAdh DRW6EBXQqTJxmxtqF3laEJelHRx3EJcQgs9qBnuZEgjnB9GQA5iQBEmAAhqWnbRQrXIBAhdTEC8Q LgKRCyzwCZ2VApU1E8j6I9+RDc8qqxCRCEcpEIRwAQeAqh0wCO7KEFNABI76rhUnrxc3EKsQaj6x HfEyL2A6ENZQcLuwDMuQDMhQBchwsmFBsD8BJQ1rFSCApAPBCbImAEhwCIv/wAgcsAgcwAGwIAj8 Oi5/CqtEwijT+C3EIAFFMxNP4ArBahBB0AXh4ATRsAx3WhKRkKoFwQLEVgdPKhB/QKcnoQCFVxAl 4Cv2wnjFgq1bEAhtlxPAwLQQ8Qh9cAM5EAursAOr0AqasEOj8AyjdxARkLQNAQlVShAZMwoC8AgH wYIFEQB/0AcPsAdZx4HbanjVIHDNynjRcBCg4C9ON6080LQDQYAHgQlv17eqICptCxEgMLGaiCUF ALQEITv1Gn4GwQUbaDJjSxDpFiSB2nv4Anw7QnzLQgtT1gO1QAGUEJsF8QjSWlWfsoAGkXJN4y15 Ei5z0LWj4ADnsQSgQGRe/1B+D7EAJfpviKepvccoLuCZ8poMtvMTTQALO6ALG0BMf+AHgAAIGCAF ezUKjiCtmDAAn5K6ByEI9fcQL8u54TKOf9J2u/AJRNYML+A1ssu7VIcG6CsQ9zIs7EsQ1/gv8KuU qjCpo5ALPNB8jrC6A5ECp+sFAXIQDyB5D1F3B7EJxDYH3De7PtsaoBCaoyBSXsMIofEdZHMQZDBt LNBYBKEJyvC+PtELXEkDz1kQuQALa+UBBUsQlyDAowAG2ALDnzsgrisz4WIHFey1cLILL+DDy5C7 EaEAlftvfIgGjEIQZMAoK8CleRINb4OUtBALPEDCt8AD/esIQDYKJ1AHn//iA6TXghERCRCoentC B7srEA7QgrsAAz6sDG5sfmcsECojEPp4ENMwbZuAlwOBAu57wGspBDuAA5k4C6yQBAIBCdLaKZ/i CgvxAGDrEJHgnbBWcgJQyaMAKLUrcchggibzyaMQynv0rNOgzKOwAmtjEJnQxDI8EQEwCWKmuAax C/KLCiR8BIQsEB3gyJ8nh367EMRUMTArEHoiEALwAU13zAahDHX8EHCcrHgyDc8KBvUCz6gsECiw BfhLEmtgCqKAoWMpFi1rZAMgCqxKEDmQCWtgCMNaEGAAA3fwgCbRBCxQgAOhK3HQQAtRCJlAAi3w bCTxByzQBA5bQSRwpaP/EAqY4AmoAH9iMQTWwA1r4cMEAQ4TXRDAMAIroJ4j0QMEwAB6kABFyBBs EH0MkQyMUAEwehGxoAxdEAbKMIajUAB6eBBV0ABjPFYCwM0CcghFKiDNkLZF1gMvcNUGMQOiIGp0 AAm+8AKW0AKtAgIZkAkz4gUbwApcbCAsXRC18AI02gtVOAoXgABoEAqXQAvCUAQ4wAAiMAqlkACe gAK0zBA9IAPcaBA2vBCzQAoKcc6tIAweyQC5EBKLQADGoANxAAzvCbBBEQsuMNoScQcSkKYQwQmU WRBDAApVexCvIAlr/RCt8Al/tRCYaBHP8DgUYQYd29DYjWLTQYNXNgMg/z26cNAGNdAGtVADAHDc DTEEqCABK8ANGkACGFAJuwAMmAAIIzAAeZAJh6DIFgsEejwKEzAkJDELoMABKSAGjHACH/AIQbAD lMAIk6AH4eAJjgABiSUBbrE1WdMhlIANs9AC1cACaHAC3VAFNsANTDAFJuAGhwADAQAJ1uAEb8AJ NSACCADSYeAC08AIfQAB39ADJeMQSTBtkzAHzzAC7/QBrwAAjvAHhS0QjIAGdckC3WABUUAMI4An FrEEbqwCa5ALHEAA2xACNyAMLcAHizoDb7UGGkAG1vAC2PAIaXAGipDN2X3neC4RwVoFqPANwlAN jiAIDnADMTAHQnwWi/+AB64AAJfwB7OwCacQBydwARBzCQkACmyADG2AA2ugCsb6EN0QAjUgDWjA CTngDZBQCIewBDCQAyWADDPAAuDACrdQAnRwCVvgC5qQuLMgAnWwCUFwBh+QAY3wDEngCGrQCcAg BwCa5wMxBJLgCBgQkzmZC47AyhFRCzoQcK+AAiwgCujp7HhuCIagCHbXAps7CqYQBRZ5t61wAzWw CnebCqmQAzlwCqeQCnR7A6dwA6uQ7/F2CjVQA6VQAxoxZRrh1eL+EyMQA5ggBT6wBSrgmTYwBbEg DMAwBb5ABkiQDL4QBSBvDMJQBSZLDFXAZMZQ8lVwBTa3BSSrDMqwBc3/wAU0L7LL0AXNsAxc8Axe AAY+HwZhEA1hIA1D/5jTQEBufgZoYAbWYA1mUA3WoPRpgA1o8D9qwA1qkA1YX/VqgAbbYE9qsAbe 4A1rwAbdAE9jDw7t8wZwEAcBIAACEABzYE5zEAADMAAEYAADIADkQwd4YAcFYAB2oE15MD0KsAcJ cPh5gDy7swAN8Af+4Qc8oAAXcQgg0gMpwAmkcLkFsQs+QO0LP1Y3URQ8EfooBpYoKQujavpTEmYz 4fldyfoCMvpIKQugL/uzL60xwZa4P1YuWhO7IAse1vvUoQhZTBO7AATA/RCiS/wkQZNFoZTOfyOH EMYosRPLP/12Yfw//2HC2a/9YsH9T+zK4L8QReAN1dADV8AGR7AE4TDFKEGk0f/95T8FD4AHt/AG hbAM02AIqRf/AMFg1ECCBQ0eRHhwiawdCR0+hBhR4kSKFS1eJJiBD0aKS2Dl4BhS5EiSVfYgoGNA QA2SBhPtaemwl49UMW3exDnQ2KWcAxU16Emwl6xVQY0elbiMU9AMC472glUT6UUuLigR+wCjmR0d CaZGjKYiqKI/T6N+vViK4I2BUtE6TLaIqVOjM9m+xWuzG41Onjh14vSXBSdiNhEJTDiDJDAid/NK fNZoRbBFDx4T3GMhYQk0A4sQCFDLCwJiTw6YUSsRA12Cr1D16iSnBf8ykb2EgLw8UUyl3AQbZEho ovOoWXXkDPGS5woxP9xYSkQE0yAeV+CiiXjOsRePU70lkkHhfZQDRQlTZLOpCPGoHidkgHIhytSK WiKjCOku/mCqIUFqBQmiv1hiucwP4BAyQZqCVqEAEQoIuaCLihJhbRUWVNGBFFRwcKG+kJ4AIj/9 CorkjQCLqCXFIUxR5rEHEEnokjMQKuGZi146qAAjNqmGEcVCiqKxEQ0CoRuEQOHiMUASSagSBQ9i YUaLNDKoBxiqiSQVF7YQSRgiRBxyFBDYQOiFZB7rA0aENpnGpkS8OsiLNqzJjiNijABzSEi4ObLF vB7AIDgp1ehEGGL/qiCGmCyu2GOTiRJRwKAiQEkNhTDsk6XOIUFYA6FOCsuLj0MSOkHKbSxBCA1M JmrqoDdkUQWI9ewUIrUwR4mkjT4fc0DNg1AQYyA1eDpIjUxY3cgoYmixNcwiEfLkChcN2YyMgdJA 9aBsVpUog1lzIsaWPEcMwRuEPsnisQQCRUgTKdMoASFrTmCVNYNQKIKkZZsdMgQ1yvQTrz/KQ+gS MwbahluD0lhKokS+HU+SYTLRgMCQqvDhVoI+SKNMLvNaQK6CrR1FjXgPqobYiKhECADHCuriGRGn MMahZTUdkdNzkwRZg4RQGG6bkw0yQ2WIMOijoDb88EOPBjxwoZWC/6opKpNwclFliFFYgAOhKYjA WT9I/j3IBdpAPvAgS97NlmiFIWI5oUj4LKiAT5oZBQ+RuxlhlBkOkQSEEEDAxIgfb42EbINcODMv BZhEyJKOR0njbYKsEavbZAe6IwMMMkjEEGAKugGGMIbIZZUjaJiiBxm2QSgXH/gd8QP0Dor2MQV8 NYgEktOgF+XwJDJk81MYcCAUUix4QYgeCirllBvcmiUXh6ZwReOBcj2SZ7z44GCz4dIwmqAzMo8o EaAKagWVbGIxxoYqRJpCXO25L/vs7wlWe3LgETKDJiZCiG/tYACnOMLL7ESLsIlHZwdpQbryogfI HaQE2LiW5QZihv/gRQQRmyNIJpQwAg8kwmIcuU8DvROJb+zKcWkzSCXe1cGCmCEFEzHErJKQCDz0 QAOWkGBI7jQu/UgCHAjhRBDfsoAKGsQSt0vDsQ5ihuFFpAKzskQvRmGK+pxAWiERRqbup6uDvGAZ umOX2mBHufINpBoClEgF/FAQEgCBFLqwgQ5koUUw0oKI4pGEGxACgzM6jhEJeeK1aEgQKk6kAusL Sv0UWDtzHeQTH8MLBTdzO2yYACHVuKFqkmaUKIhRY2M6V+PwogD+GcQE/tPgKGz4qDke5AArSEGk RNIEH/xxhUaypCrfooANiG8g2VikG+EYEQuMciBbqAQfEFEJSkD/oigfOsspyVTGgI3iFMqoBiy4 sQzc4ORxTarGtZZZw1ASZAA4sIEPQhECghxiVqmwAyAgEInbieQJsvBlb551EFAUsiA5eMEtjKKH YkZuctlooyylaJBabJMgFSgLQRyBBzA44l8BOII/iVBOZymuIJ1Q4kBWEQqFBmUPaXTiu2LZyIFw AhaceMELPOGJT7zgF0+ggDN7EqRJ6gcElTRIC/yUhDsoQA8IMMAdDIAAOwgDJ3o4ZOTSSblkjuKN BOEE3vIXgVoGxRch0h4qcde4AvjsIAyAwFVbWRDOIKyrNB1FWBFitgdAsidNAEJRE0IGULQgBjDo REh7clSErMBP/3QI30EAEQFzwrQgiaScJ1E20RaAAVpVGERGgyIMINAOIq0QKkFqQYFEJAIRF0AE BkJHAYNKhLFQKuQAOoAQBwDCnA21IAYz+8l2dsILferrUcJo2oNoIBikMAUqbIAKVZjiGIIcBRhM kRAGlFUiHPPUx+Sw24NEQBAGAcQjHtGBgVaEoZuxxrUiagbOSgh3VYAAxG7ipYASJAT6NcEABvIM WCREAoGoSAiwaxBPFFIAjeAtJHPwCsUophQ3yAFzE8LKzQg3G+2cWjtZcNwybmEQllEWLA73EEfY iyCYoMOAgZAQCMSVIpFYcEFW0Lg6QPggvR3IEkTRhF0UeQlJ2P+FG1xQkd0Zk3Jtq2EVXWCjgxBS n0dhjFtY7F2CnKAOMk7IIHx7Y6QWhBONI0BWDfKHUe7iE5P0gieYDNwYji+WoCRIJ6ic1CsEwq85 mQIDBzIIG8iCCDQQmUZFWxAUEGAgYNCBgRFMERDQLak8owN5DfIAFDchBuMCQwvmjMjxadZtBGmB WA3ygiwAAsVBIQYQVtwAOmuUywPBxAEGnDGECGLME4lEmQlixoHQwcdrRvESQDGuZyyZIu+N3O2y 4SiULbMFl6ryMh7w6558LQd4uMAhDlEBQ2DAEBdAwF08YGODYOLL2bVBQgohgYoE21OFtIOmCwKB MSub2aJ+Ngz/L7vGaROXIJ5o00E6oQxXH6UJRNiBKZ5wkB/wIF+jcIR+MVGAR8cbIZyuCCTWaJBP NG4AkTWIAya9ixeMqwtyfrZb+zcQNICYkRPthGcPwokuNLwuQGgFD75YkCT44OKOSC2uOT4KLxQY IX/gdkRYiMSP6fbpKw/FNQvSDGdPRAGJdiIUu1oNao9iBdhmsBeubJSH7wAV+iPIEXjQUkcsustz GLDTD7LtiqjVICzgGQFQXhAH2Jjlk+xCJ9w7V4JMgmxnsPlAyLACgqjgSQZRQc8HcZQnICEWrkjp KHKhAw+tGyEnMMBAvJA9hECAsjdu4UE2YV/I8vb1SfDEJJcB//CJ6IHxA6mEh8s+tbK7gGSYb8YD 2N2ThbwCB/MzSBJg0dJHTNogJ1j6M1h/EAi8WiIhOOJBNFFIAziCt+cdxeEPggzFU0QBajYIJeiG OYSQAX0rCJbCnwH1oywB6DqAu4GoBVQ4Oo1LvVF4Bh5ICJCjtE7ZuUIigGMriD+gN9FrgXFRCveS OVdaozSoooKYhrJLgYQziE1IvtcLil6ghR7QAUwiiFyABcVyhKgbCBQ4QC/gtR+bgAR7gzVpnAAY PIL4A/TbBVDQsoHIgobxOgksCMeTvDtDH04gwYJIgS74A+tjPiJwDWEaiCBQBRmkwVE4ATsYiGZg hQUMQ4cokf8y4Zk7YMKBULmBSAIXmCRl4D2JgDa1IRtsiLxRmAbKGwgWEC7Ms8Llw4hl0DmEWIIV pIGhI4ghYAXrGQUPuDUxdDQEVMCP876IAIEePIgV4JkAML+D+IPbe4EjHAVlQB88bKLLIps0AESD qAaYG4UUkBKD0IRnAAQstIgosIHn4QQAUEQg2AFVcMGBuAUfkERH2ERcI8NR4AIcSIg/sDuI+ICR OykJkoM3HIUhlEMXcLnhiwgFCEKCoIQ1mgZTK4homKgUuDwdS740lIg8yKpuIAGEqIXsiYEmOIgd EIWGGAVGcLGBoAQBGwVikIGEWAD9cohGGI52s6pR8IZWHAj/PUiWH4jFgjCGWHKIO6CAhAgBKZEG SkAIZeCNgTiBPWO0ZGAAFLyIWZCBLjgCGSAZOvCDBugDBugDBOCDPGCAB/gDPwBKQAAEBQgEqOsD P9jFyTIvCYC6QRgEQXCACRgEChi3QiiECqCACkCEQ9AARHCtDFAERNiADMgADViERDDLRHiERtiA D/gARnAERXiEEICED/CAD4iESJiEEJgESgiBSBABSaAED5iEEZiESaiEEaAEEhCcSigBSiiBSjCB yRwBE4BMTDiBEzCBzUSBS8iES0CBTBhNFEiBTdiETuiEFmiBT9gET8ipT+AET1iBFgCFFwAF+ACF T4ABGhAF/1KIg5G4AYCMiFXIgBbYhERMCGKYBYgwAzxQSYxQAxIIgfh6iFX4gYdYAkXYgNp6yRDY hBWIhoh4BuJECDtggUuwr95QgxhYsYLohVBAhQBwiB5whfo4BZLiiBvAgdFJiEcwAkJwiDoAO5I4 gJNMiDYQBRjwnl/xhh94z7xwAEtQLIRwBBvIhk5AhOyUlzGQgHBghePDiC1wgXBwCDawhS6AgBFo ToTAAFyoAm5QhVcQiUS4AFQkiB0QAkmAAyCIAPMsCFawgBpgAxjIDQOghUXwAESgUYfoABN1iBa4 gysIBTLCiCtAAqGEgIlziAIQuILIBRk4gEHYBBWKiAaghf8SwARG0LqE4IQALIhlUIVBEIVK1B6J 0LA71VPvIAbr9I4q4KM9FdSJeIMEQIBiAgMG6Ixm4NBLUQYG6IY8DQlsQIMKQAAEDIeQ4tJVsB5j 2AZJnIoJuIBBLYgf+AQPSYgYqJk+AIFVWAIxQAEKmAVYeAVEKABj8AEAiAIVkgFLM4hboAEiGgJS aIhMyANfKAJkUAUr9JkYKIIFAKJdEKyBaIVPCIKHyATvLIhG2ARCsAJAsIYUeIMY+AZFqAAE/ARk oIEIaAFhMwgx0LegiAUYQFWEgIQKaLoRwIMS6AEWAA5kuIZRjQYJ6IUQ8ACH2AQ/pSgYCJscAIVs MIZiUAD/FhCAILAF2siAMhhPOJiGV9ABkzqIVhCFa0XYbiI6Z5uACQADVoiEGBAIEmgETZCaLnAE HOgahzADBDWKWHABkr0IL7gAfZNUFpicg7gFG5jWGTicHVCLUtiCSYDSUSgFIEWIHgCFE1qTYywI YTABSiAENHgCEdAACvBEHqCNWOAAGhiBlkoIM4CyoHiFTqBao9gEbCyIWgCFt5iBT+DQhFCBKMCI AmgAST2IMPhAozADOIADORCAOBAAApgDAaADAigAO4gDObADAzgAPNBcPLCDOkAAPLgDBMgDPMiD BVCABeADPmAAnNyDPLi4gziFAviDBxgEqoxKCojKQSCE/96NgNsVhAkohAmwgETIyt7NygpQhEMQ hArAgK6ULQzgAzM1gEZYBBCQhEfwAEjggA8QARDYS+oUARHw3r8UgRJQTBFoTMiUhMRsTBKghMqs BEtIOlK13/sdkVdwwFGwhimQhh+pgWog3IdIBi9IglG4BS64gh85Ajg4ox7YgmcA3IIwzxmYVoqY hV6oCU7VmoGYAS7g0h+4BZ8VVDz4ABKI1EAQgQg4hRoYhBBIGjYwgUdIgR8AgQ0AhTaYg2iwAkvg AgGYgQIIgQpYBW/QgBAo2oe4hXuEA0a4gCR5qQnAu1EoAgjYX4IAgE+IrB4wARjgx5BIAk+SA0iA BAn5g/8JoANqqQEvMF2K44QYaFJCQAJfzQ0PEIMd0IRA+LIAqIAbSARGsAEyoBdfQAENmJFGkIMT mIESEIZSyAQ8CBRluIQ/2IZUUMKHGAJUuIN08YDx7IJIaAQyEIYOWIQ+kAAw2AUEyIQDeAZWKARZ 2IgUGF8ZiFCKuAUeEIR/qQS8QQYSwIA0eIIPwAQDkIQ22AIBWAELKAUWKARJoDw9QIEGYIIlEA8z yIUb+JduIARzmQE9YAA4aAVjMIQ8+BcFiIA4AAYjqYJEmAY+yQYMyIMZEINdjdqHaIWbHYU4WIQL oJsFyF40IIP1HIUc8MRRuAM72IWBCIN6togggCQHoAT/DrhECaDMBuCGHBsFBPDPN3gEKO0Fy8Lf kBbpkSYJX6DjgqiDCTYIX8CDy5gBbLhgiKgGtiVpjiiCExCBB1iGQMgDGKAEC9gBS4AaONiAZ7iD SJCEiROESzABSOiFTLAECoiFD5gEQciBRBABQhjgUagBRSgBRuiBCLCER3iCAZjfAgADLaCEKUgA MKAER4CEIOCDJCgCBjgFQ8jpG4CAHTCGAUiGR/iAZOAAOtCDUXiFd6tpi9gCDDgBNWAEQDAXY908 CdiDQ+iDFmgDXTUGkgSDEmgEvOmAOEiGDsCEBiABN6jYiTiAMeOG8NmFEyiENsgBTbiBEUhoFQiA SBgFmUWYg6voBRe4gOBMAEJAgR6ohgv4gQvYhGzogGeIAxBoBJpObImYATOQg1hYBWHoBa2pgiOY gzXYgDh4glSoBTs4A8U4AgOwBqvCBjxI6DU4Vmjsg+iEiGjwg4MxBgfommTYhVI4mCcYBGUgA19Q kGhoAl8YhAHAIDeogI55hkMgAGnggit6hTTIF0ngwukmiRbV8IRohQYNCAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209005.gif R0lGODdhvQDIAOcAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeXl5WV lZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXd3d3V1dXNzc3FxcW9v b21tbWtra2lpaWdnZ2VlZWNjY2FhYV9fX11dXVtbW1lZWVdXV1VVVVNTU1FRUU9PT01NTf7+/ktL S/z8/ElJSfr6+kdHR/j4+EVFRfb29kNDQ/T09EFBQfLy8j8/P/Dw8D09Pe7u7js7O+zs7Dk5Oerq 6jc3N+jo6DU1Nebm5jMzM+Tk5DExMeLi4i8vL+Dg4C0tLd7e3isrK9zc3CkpKdra2icnJ9jY2CUl JdbW1tTU1CEhIdLS0tDQ0M7OzhsbG8zMzMrKysjIyBUVFcbGxsTExMLCwsDAwL6+vry8vAkJCbq6 uri4uLa2trS0tLKysrCwsK6urqysrKqqqqioqKampqSkpKKioqCgoJ6enpycnJqampiYmJaWlpSU lJKSkpCQkI6OjoyMjIqKioiIiIaGhoSEhIKCgoCAgH5+fnx8fHp6enh4eHZ2dnR0dHJycnBwcG5u bmxsbGpqamhoaGZmZmRkZGJiYmBgYF5eXlxcXFpaWlhYWFZWVlRUVFJSUlBQUE5OTv///0xMTP39 /UpKSvv7+0hISPn5+UZGRvf390RERPX19UJCQvPz80BAQPHx8T4+Pu/v7zw8PO3t7To6Ouvr6zg4 OOnp6TY2Nufn5zQ0NOXl5TIyMuPj4zAwMOHh4S4uLt/f3ywsLN3d3dvb2ygoKNnZ2dfX1yQkJNXV 1SIiItPT09HR0R4eHs/Pz83NzcvLy8nJyRYWFsfHxxQUFMXFxRISEsPDw8HBwb+/v729vbu7u7m5 ube3t7W1tbOzswAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAvQDIAEAI/wBJCRxI sKDBgwgTKlzIsKHDhxAjSpzIMAuGCsoG2lEk5iA2FBRDihxJsqTDCw5MKiSTQqXLlzBjEjwUQSZB Lyts6tzJc6AwKqtgCH3lQ5EEnl449VzKVCWwV7QGurKxiJBCbiIuANIg4tvELaGaih0r0VesIVJp VCiEcNADglU+UazSiazduwl5zcI1MMcpChYS/ilScsqLGXgTJz4yS9dAU6MoMEL4R1pBVYPISDQm w5Tiz2R/8FgycAaNQY8UHtkkIxQMQBSbyKgBujbTH7WAEQw1CJJCYTpOFWH0diCHOgJ1xQCjSuAM Y9CrCDtDA5Xt6yZlOapESYQIcAJv8P+IQhBGBA8L1Zg40SAHRVw63GOfH5JTFoIi3pBCBWQKwU4O iLDQExiIEgFfE8GSyg70uQQLNs7AEsU2UZHihicEuVEJTCtYQ1AlAZBiihBXEOSJIJYolIAh0nBC Syi0SbQDDj006JIqrvQAiyusCKQGhgOhsSFFK3Q0UAnbkNIJNvgRQMoMQCRD0AqEmKCaDEpEMAAH FKFSyg82TlSAJGoQtA0LBFGjCSna5DTQGUNOpMI0BJngBimbcENQJAgI9EpGA2UCCCYLARLLKzBI OREqp1RoFyor4CDDKjqkIsoRE9kiCkGmvAAmGi8QNMYmpJwR6kBmtERRCmYQNEI4pGD/kuRAHRgg kA/OEKSJBKrqVEMpjpbEiiEdOPJII18IdAqdgVJDiiqnYCpQDqsomtAVjzCSyAaL6CbLKT0KxIoM hEkDA0HPtEBKNDIgJtAzJ4R0SZkDQRJHrPoN1IgCfoJB0AkTqNCTDU1IFMgvrfDgwyxO9EmKKGgQ 5MIWpJTS6kAnOIuKKKQJpEorFCcUBAwxktKDKEXkIAODHofiWDSp3BRWNKW4S8ozvSK0gCIENVCC QJWAV68dpJAA60CMLCBQKhcLREkEdfFkg24RKdIAQYIIItALEQ/0wjOkxHAGQZmkQUoNoZAnUA2r gJ0QLTo0J5ArodhiigyyDITKC8KQ/6IMDjYfEwMpXrQ7kDJAJqTAZAPxYSUpkRwtkAd5kAJCAQRl MIhApeg5EAkUuDASGGGRwocjCLkASCMEBaCUQhQUJ1ADm5OywhoEcRINKaF4NVAl3QjUQhWl4bB7 QrCsEu6zn/BimqOmeELeFTZ4JlAVo5BSxSk3DGTMpgrZ0QFBBfxMygdzELTIHqRoYOtAhlCwdb6T E6LuUtK8gIF14jC7EBwqMEZB3kACaqgATARBwSkWIIq+cQoTnlgFLxxiDU1YhiCu4IECQlCJGg3k B1QIQAAIRZA7fCABIUAgQ3qjQoEkwAV1EIJmCPKAWGzBEpi7SStUIILuiSUHzriCF//WcAa5OWQH ohgBB7owjQdEwg422J6/ClGIcMSAAjFwm0TE0DWCAAIENdAGFprQhhpIwwek8EQ4PqaLTjSgCNPw 4UHekLeCzEAcLRQIZI5BCgOMgBS6iMMnJFEDHTjjARLYAQs64A1XIKQHBbDZTiJwCQ28IhGHcOBB dgAFQzhAEH3oAyAC8QA/AAIQERiEIAYxiEAIwgITcKUfGBABCPhBEIB4AAQcEAFACMIPISDVQdoQ A0+o4BMuYAEoQvEJUCTTBS0ABQs8wYJPsKAFnmhBCzrRCU9AM5ugeME0lckCxxikA6JowQpYMM0W fKIF03wBKLB5TU5Y8xPeZIELnLn/TRa8IBTc/EQnVBAC69kGABcgxQgOkKLooaIKHliBCAZxpw8A YhKkoIUn5OCIHJBKGZWwQPAOYIFKJIEYjzOIF34BAgqwAhO5EkYnQjCNLITAEACgwQbiEI5PHIIU kxgABf4YjUyckXgMwQAdBFKAmoyhEosQgy3UdYKoaIIaP3MAHy7Biyls4g+Vk0MkJsELXahgBnBI gQUAoYchyCASzAgTRQz6EG804Bi2EAMw0KCHJ5AiC3zQBjEakIAZyCEAtDEFAcSxAl8cIQ+tCkIe wEEbAMiBrgPZQSiCoA0VYMAAP1hACKoQihrBAQwtkSQpICGFZJFCGsG4hEtccQkt//zhr0DSRSpq EAEOPOIRjgDBJj5xz2a6QKDT5MQK3AkDaLrABTBogQuyyQllRhMGnuiEM+X5Ce4+15nKXMFzrenN 7j6Xm/AEhXjdWU1/YlO5n1gBNznRCXhuYhMrSME68buJFLhgoCtAwSZasIlOKJcTA2aBgVWQieGu gBMqWAGDuekJTrRABQr2xHCjm93pegIUngixJ0TxAm0+NxRj24k1hCnXFkOEFSRIRTfqoINF+MIT K/DEbXfyhai5+McRCYIM5FYB+e3ECz4GspITEgUfqBAWNFBE7XTihfst+coGeUIsHLUDG2igAgfR wAEuAQtYUGIkx7AyltdMiiTwwP8WA1FFKShgZJ1MARSqZbOSdeEDwujxihhQyACycQ2ihWQKosCs noEcBB5MUI8yqMAGeBKFU5Rs0Ur+gQ98QRAZCMI3B/nCAeYgDgEEwA5joIguSmEdTM9HFVwQBip0 MQZW7EAafNnBLDT5MAl8ACEFWIUoWoGDUghhAgRhhAAEMg0fJKIUeDiILnBgRFc/JAKegMM2XsAI X2AiFCGDiQq0QZAbvEJtAnHBAyTBE1nYYHnWhogpPDODG+TZIclARCCAcYANaIMMIMjDDHTnKgDs xwfEMJEg4mSTHcjAkfGGyDdEN5A2MDwinCjR5zzUCXIPRAT3MsUsNC6QTgDijwf/OQMlPNCBSEBi BCmZSA5KAfGIF+QbpRMINjLBJorr/OIQ6YT/FBq8jhPkEYZ+RbhtJwgSLCQJUxBGMu7dEFTYIFg2 Fwga1GwGgZmKIGZYE5E8NBBK3AkTHheIIwwtBH8NRAWDADpMUEGDIPREDQQoAAHwcAA5gEllaBEI LGbBR4kE4d2ZxRspsJFzUoAhJ2dovDTEPhFNzMppcCBFJtpw9AQIJBZGEggKBJEzmcwgBn42yQvc LhAW5OoUZBdICpikChqYkxSssKFqpCCBCExgEBjYxQ9cgYOaqwIGhAFDKdAVqmiATyBIXkgD6kyK QGCUFCbwBkEgMQDsS659DFia/7N+F4gk24QGHYOIIvxAkAj0YWuXJwULMgKDtMeqVTUARfpV4QMu KOQHNmBErgADtuAXHkQKNxAKE/QFNEAQyiA6NGMzz0B5OrMIBMEH12cJnDcQHxBtknAvA5EBO7YK niMQIyABamYTowABLoAGa6AG3NAIoLAQFSA7pBABR0EKn7CB6ZYrMiA0AkECZTIDL+AfzpEKroUQ P6ADNccKL6ALM9AoA1EDn6AbybAKBlUFg3MMMtBqpJAMKWgQeMA6A6EAsmU56aMvffIByDEQiWAV pCADJUgKlDAI5jcRj0AJfZAKasMKtrYDfshm1eYQQYBudhQRXvgQU2B3tpEEzf8Bb1iWcHfBBTnk YsfwCR+gCCZgCXlEED+QC6knEHZQCiPgAVsAQBkQCRTDBbtFCszQCTGgCDV3EGgAEgchCJNmED3g DLLgSEEABj8gC6ggC5HgJAJxBc5waQYRA/dhEC9gLQ4hBoxQAoqGEEeAA8q4ZFsQeDkwBrZQMALR AyRnEnKEF6YQAPIxEeGQYlnXji4BZ+4oEfAiCX8QDYhwAODRAUNACJVgAhkQAHKABp0wAkSDDSzg AbaXCJeQAtPwB5NgAseABipAAndwEKogArAgEIDAAh8QAn0DASHVAtEAagOhBhX5V5twAa3mCKEn EjewCGSwBbNAPJOQCFzgCcv/Fo86yRAsYwiAcAOp4BgAwHMFIQYpspNAlgjvtxNkQEJI6WKFEH47 YQa2+JTX0WqJOAFaw5Sl5xJUZ5UN8QwxgAPQIApViIM88QxECZbYYQqVSAFscWRdyZZ4EQWxoEKu MAqLYIMy0WN0WRtLsAqMaDI2kAFgthOv+JegAQytUEek4AoykAiGwBPOgCaKqRhNABVSUQqG8FMG MQU3cAN4UAfpSBFZcIeXORZJkAqDCZkVEGgIMQSFMAIisAjHMxFZcC6piRdJEAvSQgo7cAoWwDMH 4QolIAqMwAgqIANxNRFTIBe7eRe60ArwiHupMAEZgBDOQAmTIAkjQAmUEG3O/wkDXxmdO8FnqXcD NkABxGkQZwAB1mMKfnCYEmEY5WmeNkELPHB7MzAKg9CeBdEGnQAozyAKO1afonCf+BkTstAKj/Yk pXAIjHMQMwAAHmAClBAIklifo1CNC6oTPzALVCMQMAABGsATUxADHvqhMvEDRMBroRAB45MQcBAI JJEEopCNLCoSytABhMALfwAJ0/ANmLAAM+AKs+BXAxEKgpAaCaEHkfAFOuAATlkHMDBDPZACnxAK 71MQvJCjO7oU5sZrMUAIJFkQzwAI0gAK2vUCNTEQj2CMJdmABqELNlCObFlHjGgKGSkTLDBDAoEK CCcxvaEQe8AvpDAEpyIRQ/+QCqUZpiQBCBfWYCtwCXwkHobIAhIgIDsRBDjAMorpDAjQAcOAB5kH E6AAqHSYeaggBIUnEJ4QAShnEAKgA30AqiEBC0x4meBQClWQDFlgDIBwZhLBCl9wBTmwBGYQjGMw QZuQar8TIjVAIgTBAoEgdwgBCwp6EFAGiVk3BYegAMBwBxjgWt+QZBYXEnjwCBqQAY7gCBowQSoA rSaYPjVAeATxCYWArQMxQb4wdBHRA6eAq+4YBMdwDNABjm3gJgKRBvzKECuQhJqXJCugqiFwLzMg BM0Iq7K6EAcAGwbAehHRZbPYjm4gA1zABVmQBXvAc2qgZmdwlBPRCRcENBT/yyQf5yQZu3SdMAFO dxBusAmXgAkudwKeKRG1d4DuqAY+t3jxkgaLunhOKRGdMH5O4xUpYH8hkENAILEo8ADmgxBjwAJ/ UAhqQJ6LcgqD6WqyIAbwhgbQqXNeN4MDgQ0/W3mxp1D6kQLBQytJt3SZ8ABniBBzAJusEAoE6xCo kAqBt2imcAZxELkBAAdk4BloMDgDMXml8nykYAYpJREmkLeUAB4mwI7nUzmk4ANeQBAqAAFraRM1 kArVSRY5EAPG9wpIFWQLMhDjghZooJsCEQ05gQ2YKxBqEhIrYLqvgn1z6AHsk7otmQIUQIEywTah qIK5MhAo4CHQ8ps9IATQ//gQshAD6TguhKENnLumpEANMkAQYhAvFFECcwgJ4kAKJwCEpOABiLoK eYsJEmCZOmEKOPCbJfEM3dAN3OAG3YAN1pEKOCsQmqAZtfebrLAKr/p0ntgKBzhzjgEG7TsQzzCD 0/DB7wK/CdEHl7ANaHAG1lAJ7EYKl9C3AgECToIJ+MsBfCAQPNA0pPC1AGwTMyADSeASomC6GUcK NGC644aAo5B+1LKx0vYKXngytuAKq1BztTvENHMT6hKBA5EUhZIIBBGkAnEJ8+skkpCGAqEB7EcK ONBFMPwAr6MTUUjADoEBekAQEKA0pPAC8QcK/icD9qcJ5FYDMKBJqrAKgP8Sm9UxELAwCrbACjZw gDfwAryACtuwfIcjOl9QCgblDImjMyc6EH5ArCbAg/mLHCAQIgOhAbBBCiT4IRIQyjZRCkMcERcg lQIRAVsJCnDsAqsbCnBcAmZjCqJghKSQAzywdAZxeHLUA6OAC+rZp/sRCn2jDCTsN+ryDDUzEJW5 EApggY3DqZJQvwPhAZgjAnJAEIoAAQKhAzKsUA/wwzZBMBJRAQd6g28KCvH8NaTgAnOICWViCtZM EDSgRQfxA60AqqpQTqdHzfnnV8lwCjZTBaKTBaw2EMlAzwahB7koEHowJJGgxqTAAX0CCTkpEBiQ gzBwJwMxCYfQtBTxBJb/oAK+cxCjAAioMxABwLAIUQivLBAQ8KYvEM8skCygENDgMQOhIEDOsQoi axC6Cqo3UE6kcHVTGAr+cQxYOBBVECpVkApyZAwcXRB2sNMCgQdHiT4EoQGV0whySgqFgGy8Qz+k MFE+PRHiwKlpYD5J4AtLAAxPIAw4IAKgMAZnYAbTkAixMA2JbQ1mYAbYoNjTQA0kAALUYAbUgA0v Zw3Y4AOCgA3YYA1koEFmQAQPINnaYAajEAHUsAa3YACbjQ3boAQLIAbWoA2PbQ2kLQZuwATdYA3U MAZp8ApqcAZGEA7YIA3TgA06EADSQAdOYAZiQA1iAACx4AUCYATYMAZi/xANA+ADXxAN0xANYzAG 1hANYCANXHABKOAFz/AMX7AIMgAG0aAJFAAGYHDemcABYOBZ1CDcnisJY3Dag0ANZIAGZgAKmWAD NgIOB0AdBGsKK0CnBPENIkAL32DHSxAKeHACp7oQqqANMwAIACoQeWAFJzmFKuBXWOcBCGAadowQ VcAFdJe7AoELMDALBuENIHA2JcsABE4DhrgUH5Ash1AIghDPCEEJiRAOb+CtwDC10NcJCeAJnEYQ apACvEAICcUQUQAEGcAIN00QA0DSDasJmGDOA3EHKYAIJEDNCjEILaABifCgA3EDl4BZptAImEAC eE4KFfAIaADIY/EAXP9wA7AZEpvwwGJRA1OQBKfgHldAHjUgNzPQHLowoiZRAwhACILw491wCAew A9rQjOHQA8+wCBYwjnchCVICCLhgBleTrU5AwOHw4/ZrDQDAA5dQC8SwA60wAUPiBiewCgBbEN2A mqTQpAYRCCdKDVYwDUTwDNLAAyJiA1IANthgCsJwC059EKIAxXr0AuFOEB0AAmfwCiwgDi7QBJuQ IrCgBTzHCyVABoCAAwjRBDywoi/BB/dhcAsBC0gw4wgRBJawlBDRDQJzi+L8EI/aECwQvgKxArwW E3CDp5C68S9hDINQAUtVBRtQAY4xBRpgCLrhABbACWSQBR5gCJtgDNv/cAfI4AfAUCZ7wAj1Owcm vqEFMQYrcAQdEAgkwA2+UAkFQECw4AUFYAeGYAvBcgMxQAMxEgfVgOYJgQsnYAKJ8AMZcAIksASk pwl5gAZhYALMYAiVGQIrEAUZwAtPwAg9QAKaMAJHsAhPgAuOwAWacAkE0Ad/4AG2MAMY0IlkEd2k sAdPYA0mMAn3sQ0koAgKoAoc4AEbMAXbgAmPcAhjUDkS0AFicAA3kAGU8Ac10ABDoAt8bBBgEAID cQmV4AgkcAS0oAkToAiXIAf5TAoOQHYS8AiHOQSgEPEHAQeFQCdgUAheIQa4gAoeIgwSwAy45izJ kPcMAA6phg2F0CpJ//AH4CANtJAAedADxEAahACCH1oDiTsQQSDnBIEL24oQXmgKl1YECPIsGs/x DFEFKtAIz2ANACHCjwFSKQx0IAWOQ4JBpTo00kRqBDFSLRgwInUlxZ5Nemit6uAIEymSJUmhemXi EC1DcUjVAOUHAqtFMabpaGBHWosSsgSByIOkRxEdAWgEMplU6VKmTZ0+hRpV6tSleyTpQUVV61au XUnZEQXqAElbkEIt8JpW7Vq2bd1CZcWlE64iNnKQIvPi7V6+ff3uhZXMhRliMEguoTEDnJ4EB+48 GkXGGhkzZrBZO4PZmjVqZ7CZsWYZG7YxZKiZOc15tJlpZCSTweZ5Mv9samOsjaE2jZo1aaEtn6Gs DZs20KGtrcacefhobZ7PWNaGeVvz6Wi2odEmHNu2bdiwa+OmDQ2aNGmsZ08jvBt2NJibm3m+Ghts y6zhV7497bgKPltrZDrEj1GqIOWPTvY4BRulzEjhLwcfhPCpC/yA0BoUIsQwwwcroPBBBjUEMUSq brBmgCSIEYCLIdpwwxEHKuRERBlnXEqVOShQxosI1MDlgAQqQepBazahsUgjmTpEAginyeRIJ0Xs QRpntpAGDFQoiABCahp8sksNZYkhK1IOGQRCL7j0Ms0Hg+ABFpIKUfJBL1RQs06+TBEmiyqiyCIZ XSQoBMJnPLGz0Lb/puChh5JkoSGDOB18hk5DJ/WKGCCCKKmHURYJVE4WKAV1K19akSVTGxYhxExC Q2U1Kl94oKUkV2RQpAJVW8XVKWFiKZWkWREp80FnOsm1WKWAiSVWX09R5BAIufjUWGlJecKHXknZ gQZFLHhqCDjw6OZarbxYddpiecEBU19lwMBWpkxBw5SSdoCDla2qWMFcY5NoxRZZT0mEgqUuOKIB SSZARK1jogV1Bn1L4neIeVMphFultCGEDlKi8UatZPJ9GNckePCXJFZOqcBipYRJxZE5xJngFZe4 qqLckENN4pUiSmKF4guYUiADk7qJiKtjbL6Z0pFLJiUHGyZQeSlt/xR44Ju7ujLmk6RZ1SWWI0qq AYZChH7QGFC2DlUXH3YmyRRRKEiEKWqasSMOOQIQIJqupgjFYbQn1UUIXUoy5RREMIBwClH8/rtQ XLwuaQYZDFmEKVo20MQLaURJgUCupnCh8UmPgJykGWIgRBGmVMlDh0IgcIEbr6aIQV7R7SxiFl4I L4Xy1ZNSJZmXtjJm8dvtpOWVJCI/xRANmNoihUsO8GYADEBhoIataLf9+DRl8cEXk2gQ5BEIhQml e++7/CEW8UsCRZDnHwSGBjHXZz98k2wQhAOobrjB/bYCDBsIEH9H+kEtnmCSUUTAf015QAmYkYws LI8rvoiB9g4IIv9ZXA0XJNGFw3YAhAWWBAYTQMhSwhGJSDRjE4/4AEG4kgQZGHCDD5LGCyLRhA6s AhzhoAEiasCKWAjDJDCQgPmakgM/zOAQmSjhVngBAw3e0EhENKIJHwAJpwBCAoHwgy3ORoobHCIV cwAhC54wBXUlpQipUIUVj5SDWETBJKKQABeZ4rAhxOoJjCMFBwpgMkV04hVqIEUQVCADGpwCBrOI BSDl+CBVgIMAv0CEAK5Akhv4gCImhIASldIDXsDiClVQBhd2V5IP2IEkR/jaMVKxFFyk4gZyJAAH sAGGSCwAGBLQQBb8AoOOlQQldixJCyIAAqbIQhjfaIEYksGBqNn/whUlkcYeqMGUIqziajekBTV6 4AozACMHUxDDN/dyS5Oo4hXIJMkLAvEBp0yjFQRoAwkQx5Uj4CCOk4yQDSogAAMYoA6xcMNJfABP UrAAECGA0BBo8E85euMRHPBAJCIgSbZ4Qm8lqUQ4yDgLY5iEBYEQAYR+YAN7AZQUxxBYWnYgJomR oqadkIZJKAGHk8zCcyTxBCAswZQotFEtslhFS604jV74QAc+qAUTHkUVL7RAEklIRCfi4AYacEsF YzDJCN7Q05KW5KQjaMoxHBETN3nlB6vYwSTdEKOSeGMSfOmEGUxSCTSiIhY/JYUnIhgVYCiiBEql CixwENfbceET/yIQBgZK8Q2SQNMk4EjpXjpxhr0OgIxCAGwLBlEJCPVABohtHDtJoajK2kwNd+2K KBZxBzzYIQ9GQAMpOLHNkoxADqSYARCEVxJPSIC0D3JFKRhrxW+AjCRpoIRXVvAFk2RCryywxl7R GNzhkkS0x2WKM2igi1O8YgJdcQUOrnk8OcDgBZ5owSTk1YbQlSQNaO0KJ6hbkkx0Q7e8JYkkfkuK WGzSrIKIblPScApPHMAaLeBoVNK7XtF94RSdAMV7RVEmNRCrJNoggVc6AQaTiCANpFhBdksiggCQ whS1UIZJlDnUpRBDDm9wwxriEAcAa2UH6j1eNxhGCmqUgBRqGP8jSc6QWa6sYBp7ReQmOFsSEAiA JK/YgklWUIiRLCUJ1BADNZzBBTNkmSs7sAGFG5eG+pIEGycgRRpCYRJsXMIrLCCDSSYhOxbktiSQ 8CwpeNBdUnTiATRuiiza4AtaRDgqqKDBD7b2NZO0QWslqTMp0CAKOoN3K53Ic0kuMdYUnJiVeCBJ LJxhEk0AAs5NmUMjvpEqUKBWKqiwgVH1JYFSiMMkaLg0ScgQEW20gM4m8IoKQk0SEbSBFJrYhkk6 cIcrc8EkKABEk5zigGLsYhQ55QoqZCDp2wHbJGYg0hmSTApsdJkrm+hxs0lxAlOTpAODJIUPrM3f B7h7KU8oRRP/SAGBSHQFFTioqejQoJeSUAPOZ2C4m43cFRSomNnONkG9SfEIGbbCzCRJgSCQ3ZQx lIIYtrADKNQ3FVSsgm0zqoEqbqAKVqDC0VCxxTBMIAJKTMISu3ATGtpMCmvE6AyGKYmFvKIJbYSV p5iIdkkekQeSzILEJUEBBIrmFFYoqys1KIXXRZSDVFjjGWBwhjaQANip0CIGFGXFKDCFhlGYZBoN wsacS0IGNG0FBXrtrUihbZJHoJrAXri2IPruF1OMQuwhygENmOaKVxyDK7SQwTd3IANMWYPTJQFD vvJuEjBomyuD762vNZFQqY+FFK94MtYFsfW/oCIVCXcQEXCg/wlMYKITWhBD02jwclf4wPJbkcUp lruDGMTKGkgnCRjoRI1gk2IMzt3KCfzM7Kc7uyQeUMCVY08STRDCww5qPO7/UoqrkwTepFBFKV7O ilcIcysrXS4rZPC1acTAJF8wtjE4BbujPa24BP8qCUlwiUsAB2kLP1JIhWWbNwiQFAdpuZdjixkA AAPIgwMwgBLCAQnUhOxyGkprmlQ4vqZYAkDAgGWQgAXYHUZRKv37IGkoBZN4htCRhsQoiWcwPaaA AxoIixgABR3QA5K4BNkpiUhosRMYqz/rA5LwAbAqiZAbsr8Yr7fAARgwgUsgARNABuFJhe0rCAWJ v8ExGR+wv//VqQBH4IBGcENBqAFYSIX8o4EPAgMZwME5iwY97MEfXIo+yJKSUICCI4VLKCaSgAQr s4QntLcGIIlVsDhSyIRAKMC+mIFSQMO2+AQqJAkWiDEZaLoqVBBUgIElKIkcWAVCUwryMglT+ARZ 6AEdYC0yAoXByUOTYIbQiYZRYJxnoKum4IO4KYk/SLBLWANp+y1L8LWSYIQH5IFRJAlMGIQr9ItT eB+q6IEmIIYnEAZi4IWrgQEy/ARmIAUZiDqSOAG9QgVR2ERV8DinqKUq6gFRsKZVoDBVCIXBiQYc MAly2RgeJIlnWDylcICEKcbMsoREJIUPGKRKAACTyAAGIIn/VAA8ZguEYHQQbNwKRXiAH6CFIbCF RIBEUgiFKSOJciSFU5jETcitGniBbMwBfXMKW8CB+6lHa0oFCkOFUBCfZ7CBPSQFC+seL9DIpeAD dyEJQMgsE/A+kvAAz5IEjSkJDQCEipzEShgEpLlGVNQKReiPkogAtCAFUJDGslw1dDSJTYg2VIgB YEhFHVjDpRiCVMBJe9wBHiA3MgoFVBSDWSqJXdwYXywJLzg/plgAsiEJPoAoiXhKUoAEahMwk1CE PyAJHCDDERgE7PuLGNjEqcgAyxRLCEjJdCSFT7C2UtC4S2g6UwiFKFIFmmyKH6ghWRGFIlCFGFgu mFygLfBD/5JQBq15BhlgHGfgTKXgA8UkBT6ArRB4TEgYpBGIyJJQhBchhVVApN4ShOr7i1MQOK3A gJIkCUEIErM0CRdAvFFQkJLQhBMLmykoidhEvKawyfthhX2sgUgzpheAyyy4wZI4htD5glLoHmaw xqRYAIwoCT44rkgQqT8bJElAo5LIAEEgCRpIxpIggUAgEgixAbjUigkxiQgIltgxiVCgLhcwTUw4 MVOAAYZKhY9iiiBohW/KARcIoRhoq5cIBTu6glXonmMwjCyoncA0NqfYA1EiBQU4rg9gPZLgAKoD AQKQyGDBUJ0ahKH7CxmggxegARuAgRiggQd4CkO4SrG00P+KoCz4oa4XQEAklB3X/KST0IH5ZApX qEOecYEjcJsd7UkfxYHuqYI5O4ZTUK2jeYoCUNDFpLFIoEqS2ACqiwQZIglFiJNTyFCSsAQKOFC+ iIFAqJySgAOuTIpCONPxJM3TXFPvoq5QeFNSsAREcs2ycrFVkNGlgAUdyL9bnAEb8DqY9FEbEFT/ K1TVSgbuVIoCoKeSMIAQa8hHJQUNoLpGoNKSOIROeYFMJYVIkIDD5Ioa+IQ8oIZWaL+kCIUHeCCS kIMjbYpCsE6S+IM0ddXzfAZSeIHHjFUXAwX4NJ1TqNfZhKv4ZIHBsYGEm4FPKKljANKSqAJOOwb7 KQljiDj/pkAAPSKJAjguSIBWRtgDUtiAaiWJayWJUHjMSZAAdu2KANCjM0C0pOgEPlDScHi1phiE KCwJBOiQFdC4E8gyT7hIUqgEJfwEryQJUZhLpbgB4jSJuSCFGKhFUlCBBYoCwDyMOQOG/yQJYfBW pRCAUCUJO3DWRnBEUkiEsUgEkCWFQSDTsmRIR9hOtTCGoCQFCUBIShiFGDiFL22BFGCBTVgBT2CB v/UEwOUET1ABTmgBFmABFdiETlgBF/iEFUiBFeAETlgBFmiBTfAEFHBcT9CEFliBTfgEFugETkiB T9gEvv2ETvAEvk2BxO2EFlCBTxjdFUjcwC1c2u0EFvAE/9pVARZ4ARdogRYI3tKN3d7tBBcABeB9 gRYIBVDohN11rxZQ3k9ogU8Y3E44XBZQ3sJ1XMelXu79BBdwAU9gXdnt28TVBNJVgdJdgZ9RC1Vg gENgO7ZYggvAADs1CVvQuJJggBJAhL0siWTQg+B7tA64hEtIQZO4ADIkCW1YgUqgSJO4ghKwhCOM imTYBBSggJUjBWdoBKWogUaIBBVYNZO4gT44BAmclGhwAYoiCQaoAGZKig7Yg3CwIArOBFpIhASY Cq3tMVKQBkTAg0AriSHAAQjYgCwqiW6AgQ74gCqCCgM4LJOYAUYAADtLCj/QhNBcuQJwhGjQBKLN EBAQB/8ICOEDeEymOANKgGGSsIpKoAKGJAVHCL9GaLFKewRTGACvdYofYAEQRWE4AAATqITleglP eIIk8AT10QTLw4SfbQpwUNKS4AIA4AMlkGRvCDEKWFsNJTEQWOMImYYJlYBT0F+mMIMEUIADeFqS 2AFPxEE9mFOTWIASsABxcYojIIZj0DWSUAUbIgVawEDQW4M3booeMAZlMAZhFmCT4AUPzoE/sACU 1BBCeAZTMAS1eAMThBId2NEQkVlWcYBRaAEk0AQUMLCpsIU84IZKsIYZCAAFMIYbCDVZQDw08INJ ZAtbgIFPUIFcGIIOIAFLGIQqYIFbqgA5gINUEAUSUK3/tSCEGGgAI6AEYlABaXgECxCAT5kCIBAG HcCDQ4iaGXmD5zmEU5CBIDaJHJAEozoDD8MBajiCJlgDIkgGBLAEU5CBJtCDGOCRp4iG81qKQoAt k4gENILHHwCHUIgFHiAFb4ABO/AAUsgCTgiFP/DgkoiBGAOeU6hlkqiBUIDLOBgBlvmAEnCE5aRe 8YGFOciE4ySJJ5iFDGEEi+sDtE2KHJgFb66WLTCDMpDqOEiCXiCQQWCD3MoDAHA7DGaKbihIkoiA DVAKXKCBUYABHhAGFdAAE3iFOMoDfyQFCqCBFxgBYY6noyUJF2BFkgiCD8AEB5CDHdiARugDfGMB /5qB/ztQAUmg1aRIAh2QYgscAnG4AxYeJST4TJIQIDGpAWnIBGqLT6hIgwtZCkFIIalwBhxohOF+ ihZY58hBWK0IB0J4PKfQhVXwbr94AHP0Y6bogVpQs74YNqYIhBOIBjD4gmgQg2kAg2eIhv2Ohmh4 hi94hmfwAi4o8C9whj7ZAmbggi1wBi8YM2bYgmd4hdYOrG5ghix48GdgBi+IBi4QcQX/Ai8ocAL/ gv3+AmlwcRcHg9yQhjGQhmhog1lAbb64AjoQAHEwgDvw5qRAhUMgARIQgRAIAUqghEqABEkIgUkY gREQASf3AEmoBBMggUr4ABAAgQ+IBEgQgUfwOUqY8v8RcD2nYBxTmIE1By4Xs2K/mQFTkPMaiPM4 p/M6dwpUUHM1dzGH8fP1dqlAPyBHKKYlCAVncLZt8gV8mwpgOAERSIQguO/CAy5CwAR6k4ZNCIEJ kOI4sDJYtoBXfoq9FOBrQoULEAZUsIZbqrk2Nwm2gXNskRgKaCLTcZIA2AUzkAExUAE4uIOR6AZx AARIAAcSAINaAIcT+IY/OIUB6ICHzYIvOIEBGAFnSIE2EAVCOICJU4ovqARXiFJKMEcu0IRG2L46 QIRk8OZteAAPCDVImIOW7aJDQAU1EIAQQIU9cIQPSABgCJ0UeIIawLM20QAEwIQmQOg7YARTIAQL KAH/Y+AFUKgDnEoCCMCDCGgAL9gnI4kDxDkBN1iBLSCDGAmBBfgDvtKAJBACOrgEYpgDHwgAEVAF GaCFZziBA9gAXCiBOsgEYNBgphADEvCbTBAePMgAB7DMK/gEOrDZIviCKjiGTQCUUhiCCugArYup p/AGThCHRfiCFxAHEqgDSMAGXJgzEoAAYOiEbWiSQVCAR6AAEBgFZxiFOQiFb9gACtCAU9CGPfAD D3AABCAFEFi3XOGom3OKGmijIcgCJqYFOEgDV2CFZ044ViCG5cIFxBeRU88AQBf0zz8gLhB8puAD vRY1QaaKGrgEEzCBMcADF6AED9idBeCESqgAYXCB/0hwhO8kCWtoWRIwTdBnijSY6jw4g0kIhFjY g08QBlDYAxnoAATIAwhQBApQHT4wgT5wgi1YAT8QAT3I+wkwhgbQgApAyL12gSfIAw4ohLFSBRfo g1SxhRuoAqBe9Ry4pciKg/lJhDHoBH4FCFICBxIsaPAgwoQKFzJs6HDgjiR1dHirBGgAKU7hTtSQ 4EgPBEzYjI0hBWIaqlgGQJBaI2JHFhcOMKExRu1gjlA/BGIAQAqOpSwrBIr6VkJgDV+4aFkaIOeS gT0XABx4seMh1qxat3It+OMIUlNIixAigwGPqRmkbOEaSGuIWFLArppqcpVUkSUJVQ2sMWQIwSrO WBeRulEQFcEdNQbOWNz1MeTIkidTrlwwIAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209006.gif R0lGODdhlgDIAOcAANvl5M/Uy6ate+3077GwaIeOd9ng2O/v5/r+//r8/+fu6fj6/d/p6/X4+u75 /e73/eDk4ur1+aelVN7j1vf+//f8//f6//X6/fT4/F9iOOLz9P7//+Xu7fT+//T8//T6//L4/e/0 +vDx8efu8vv//8LInPv9//n//fv7/97jyOLs7fj9/PD8/vD6/uny9+7x8uXy86KwpOnv7e7w6Pj/ //j9//j7//j5/83Y2PX3/Pf69O/19pWWQUhLMd7o2M3WxOzx8//+/9Dg3tre1Ofjw/X9//T9/vX7 //X5//T5/r3HvuPk4PL28vL08ufx8fz+//z8//n8/PL7//j6+/X6+Pr58/T49/X2+NXYvvn+//3/ +fn8//b+/Pb8/Pv791ZWKu7p09Dbxs7RxOny7/Ty5vb+//X+/tHRs/b8//b6//L6+9vp6/L4+/f3 9ufq2drZv+309oKAI/3///r//PP8//L8/vP6//L6/vf5+e/2+/L39O30+bLBv+nw9fr///r9//r7 //f7/PD6/+76/fT3+ez4++v4+vD39ezv8d7g1q+xlPf///f9//f7//X5/fn695GYffH1+TU2JszI mf3+/vT///T7/8jPtrW/oPL3/fD5+/D3+9Xdxu3z+Pf17vD08fHx6Pv+//v8/+fs6Pn6/ff8+/D7 /snPpsLBiOfo1Nbh4eXk0vj+/+3t5/j8//39+urv5Obq6trb0fX8/Ojr4uz5/fL2+fX38pyhX5Si jP///7O4hr2+p/X8//T8/vX6//T4/uLevtrdwOPn4PX19en088XSyenu8/z//+fs8fr9/dTa24aK P/j/+/r7/fL6/+Lo7O/t2/D4/e32+qOmjXFxHdri5PDz8/T07by6gfn///n9//n7/9vWpvj7/vn5 /9/u7Pj5/ubp6ff5/bC5qvL3+Obo32txWdLQnef09+3z88DDqe3y6fb///b9//b7//T5/fn4+MXI u/L3+93p4+Lq3uj4++7393uBW/3+/8TNx/r+/PL9/vL5/gAAAAAAACwAAAAAlgDIAEAI/wB1CRxI sKDBgwgTKlzIsKHDhxAjSpy4cFGZRYv8UGCxQQ6JDcjkyAFZoYauDR2ySKMh8E4vObqebSBBpwiy jiI3CJx5k6LPn0Aj0lkDg84zdxTKuEMqrZc0Vtqy+Mk5UpecOxtsfNB2kgQNZCT8tMNYi0WRDvzo 8OMatK1btx6kPKMjhS7dXoxq5PVToxG8fhq46tyJhA1bD7W0zWOgqUyRmjQc06HD8q3lyxEfT3ZQ i44DOmjoMELD6si0XiRSZ0EGdqoc1q9JIEDj59kgD4wYeSiiKcIgU4PaYR5OPOHZIrWklBHUohdl NA7KUHDXy10Fd3mzuMoi249U73605f+twYoRA3DuCjng16Gdn+Lw45PQps2PWPr48/uhw0KNH2QU RKDJSSf5sUEWRdAgRxbTmIIMfzTQ0AELZbTTDjLxSfTONerIsc0W27iCAFiwsUbCH6GEMtAGOiFT A4srinRiGu+E0s8729TgCiMY6gKEPn2AoAEJ0vixx3sPyUiCSF2MMRUy2kQYHg2LtFPEIrpQYA0O I8jByChwhBWeSHz1gQMrg0URAEshQTOMAS2uqFNHgyGzwxgEfdCPHZGogMaHNmyxRQ0IIOBKoKzB uIEJLJpgziUzIPPEE3hgY8UtiIzChgEG/FGDHwiYpEtY7sjhSiMd9YQQWDDpEmqrAvn/MQw5TKBx CD1hCIMFJwpoI4cfRZCgS4kh1enEYAQu1ONAeBhULDL/ISlQGtQ20ogNh34IDAikICCHEF0kO9AT +chJiQlPmNpIFk9sYYcdf26zDQbq6JJFL7Vwt4EQQohUEEismfBHjx6xOpIcmqTDVVXAfkSisArJ 0cFAa6zhzEChIJuQigKZMKwUPXZUUBq/IIFEGh8Ag4QFaTRCDC02mFCsxgvNKdJrJErVox+9VNDA DhVsY8E7JhBCQiidiKqLtDDaMk8owDzwGkwszkSqV6nZN1BVEDMkiiLdBLI1jAIhAPEIcMAxwk4s VjWQFRz0Iw0S7/ySxh55UGtBAh+8/5NAAls80EgDIphggihbhELCpCP9sU49CHi6hSshVsAIKzVU oBMF27CiDx/RzCCzh8JqIQsOchDDwUl/bMANHFt/tIEHWcjAwB2MsDDIAGSskwsX98Bwwk4CIdOI YAdRqgweyNaw7Ir/bgBqWKkJIghBrrjyywdHhFj3By1PYcO1CSDRiQmRJPFHAn/YIE4UJgRqAzdp rGyDBUj80s8mcNjxzjtH4AoNWGEHaTCiAtdwAzvuQKiSaINELeKLgeaEjCzQxyP0CY823FEfbXil HfcohlWWlBoSvEMK9CHVasACEqrcZDAwpIpHIoEILNSDFVnIQhoYcA+CnKMH5yCHLv/q444jHEEO CLiCGGYxqsvdLDbzqUHWtEEFPTiAER9wRzmicQZ0cKImdCiEEXSRiwIMsQI5/E8F1KANCiwJLCRg jRwXlIo3EIEH2TCHJcZ2kFTBRAVA7EEBkFGEIuymCKxghTtoUINeaGIMhwgLfrKABu6Q4AN3+AAr 4IizOLIoAnQwCAl+kQkcfiCOxCMIzQ4Ek5DgzA+p6YUHclQBHBhDBzo4BDvqoYlFHIgV/2HDJ9TQ o0KQoAZZGAkrOKCH+SSqESOIwjxYcxIWIWMbWdiGgl74RIFYLzmq2EU9LIgDTvSikUeoQHlqsA3W eOc7fNkGCWzghh/IbmBtY5HiCkL/DFikITesCIQM8CALcvRBFWuogLPgobFBucOEncADJbYBSzGF xw/uGIUq8CQjCqbhDKmohxWANZIWSeoTtxCDANCBBVWB5A/yfI0bNfYagUjBemMAhweecTk0oMFy JAjEBYZVrJyE4hG6uMQXqvGFSehhIKpQBUFgZZBfMKIgTYiBMZAxBY/p4hVkeIU4elACEyAgIV3T hRrWMBAqyKAMWnsIJ7pRCg/NYxsC0UErzqADtK6AZgVpRwc64JhZLMKN2kCDHGqginosBBYGSEgC EPKIKBAELDWozMB0kY9bALYNoHieLqhw1oFsgwqtcgc4kEEJOPhrIQ8cSFoF0gpF//QVKHXyAysm AAaEIsCDgDWIF2hBEGlNJBBxpWpCWAGRKAyveIqQBA8yoACEWCEKTxAIDvBxBuUiRA6vQEc3mACR CJiBel4gQ0GqQBzRklESPeiBNmbSkUg0IBL92IYtOhHcnUwBVVOol2lLexKYIIBs5OiBZShBC08M BBuv4FhBvOAFXRCiAQWAxKiyZtHwhAUnfQAAEkuIgG0gIBRRsIIFtpAAG8jPBmm4USO2EDOCoOEX v2gE5RAgDc1ZQBycwMQEhiFQSOwiAEDIwR8QEoqzPmAg+WjFAHShjAFEAQjz0IUH/iObUBDjFt5V 1EBM4A1XxEkg8XgFQeIhEAn/y/9LJBTI1ERCzT3EQRJ4lkQcCGA2EmyjFLvgASe42gZA/GF9WyAG KMbBjUYnYBwEkcb2bPGLBsQgDnHYRTDiMAlMEOAMTUBEAAIgjlhAAxFLwII4kpGMY4hgCPKoLjvI cYlRAAEHb0CHBE7RDR6YsR8ekGKrAgGKDaxtWP5CQB4KcgU8nGESYFCED/q4A2hYwbtWIVujxGEF XQADF9kAA3ttFsebfIDXsPBCApCRIhOE4m9/+4MJHt2APyhBzQIZAQ7osYd3bKET6ugECLYgkozp YgkxAJsEmFqNOAyheE+wQCvx2oZcmGNYjXBBDd7hiiNkQReYuIQ6ynENW5CAD7v/IMIZaIEAW3Bj CbBoAhl4wQt8TJtFV8AGmxUChSAQxASgIGpqcNKTkHwAFYrQRQI2kIwSKCAUgPCIK0SRD33sggCw eLcoEGCOVWxj3n8ThSjm51WBwOECR7DDETIxgr69Q8cVOBUaDhWCfOBgHi12xRZODDF8VKO7COiD CvrggnFsoXrPWM0GyrG9D9jNDplogAU2gANUCKMbu6hGNXiAaWHkhGZPQME3+igQKEABEDtx5cNQ dOjDJSAN5uAEGG7RhAW4mBsWsIHYFSEAEnAjGbbcQqMBsQU83GJ+CQDEZAfiUzpU4Plx18vzkYmE TFTAWkCYAjdgauJCZXMbcthS/7uQAQ0+WOOa10+nHRghB1b0QRG4iII5FPCOTNRjFavI+RnOIAPw NcIEcpAAKYJPJ5EPOYAHULB0gJADqvQBBREqZkMohRI5IPIHLIYufxMKAhAHwYAMIAJvfzMFt7AA h9Z6CbB9gBMCeOAMbpYhDYEMGfBDESIl9GFB/wET/oIMaBAKKqARdKAxc4Isr6ETU9NfLniEFFFI SOEOdJARNKAGaEABWQAV/cAGaNBfItMREDNfYBEl9aFBs4WEYjgR7qAZRVCGddELpAFQupUFWqgq 4lJgOVQEvVAGNbEIhaQW/LAWY9iHE1EEhdACglAXglALglAdPlUDaJAO0vAAlv/QEYqDIRvwDIUg EGOgCuXgAKxgCWXYC3RYE48hCCxQGX5Yig3BD5pRC/ZwhjBgCFlwBwakSGoITLqRBSNCPd0hBRQQ F1nACOGhAWZBB4NgD+kQHKZ4jLA1GY6xCBFCB5uUBRRAAYwQjeUmEttQEsIyHUXACILgTtogDfRQ DHlohx2AEWGIjLkAROdwCGrwDtJgBzF2BAhgiyDyRjdRFRtACF2ghXIwDXWwAQgQd1IxCj5wCBGw GjIQWYiQAfElA6myLHPiLDL0Sm1EA2qhQcyoDVVSSHzYCfHVA8ZAAkvhAYIwHxdlH3I0dB0BBDKA BtwTAi6wIPd4M0tyB+8REmn/lTmuwE4VYAPz0AnicHVuYAVWgAc28ELFoxPZJRB/AAyhgAx/4AWP cAu3AArMgAp68AsVgCGhgFfu4BpLIhDu0AhIkBMJQTYQgAWpgAn1gAyqAAs/AAmwIBDaYAkUEB6O wRXQkgX9EEd+GRJLQ4Rug20CsQSjUBDcoAdHQEybMCAiQxA6tpM5MoEzhiH+ghPIoiLBgAqTcAmc ZQ7B4ANy8AfzWGKsYCjYhABoogs49A49MgIqYBVpkANNwAE1MFkksJUFUS4rkhpKokGNMUL0IWdU RYQGYYQGYQ7EdZyNgFehgAl8MDLSIAsT0Ag4hgTgEygnli7IiQy8WRDIwA3g/wcWTYYMkaMTz5AH O4AI0gCHBFEBJPQRcmZw/8IHKvACKjASeWAKHlFR0FI8rVIVltAjT7BkBNGCuhAEYkAFEQOeVgEr yDANMSYNKJMJcPAB13Io1+AK7vYEJoAHIqILoLAKVhAK+CgKrTQwctQLUtCVQzAE04Ah9QEbB+E2 0ENNbYYGlklyQvAVC0If7qAKh6ATfgADwrIkhWAKJoQGJMAdEaETxxCbBTEO5lAOvWAPIJEDcDAN VzUQy0AOxfALrmABA3AE43MtgtJowuduT/kaAnNicqCloNAKIZAJwGABrrAA0cAEU0AFePAHOwIT l+NJOlEozlNg4/MH4xAOBv/3mM4yA2eADb0QHkmhBhywCF6xZUuTKCYgC4ewACyyA2EwpDFCM7Ol E0tiTXHEBhFgH4YqLa/wCSKACHhAoyMkLNcUMlPjKgGQAp/wK/8BLfaRNUPgBjoQDCXACfTAAV2A IYFQD8LgdEVIqKm0AawgOyRgBQMgbrJRXEl5EKCQAqOiDRCwA3KQQtQDLb6ZKqNiDPowLE16mnEU LbfwCRtQASogLGJmEBpEA1lwPOrKCrXAXMc5EuKACdHwFa1hQRgCFRjgBHfQAjQwA6dwCrmgAf/B Qd5RGkdwOXDECMBwCsJgIO3nAL6CIoiACd2AC2dwAX4wDjkyAFVDJwUGFgL/MQi1MAiDQAce0As+ awktoAmF8AzvkIg1QB45ZItZgEyMwB2uIAfq8APgQAePqHrFogsGKhDakQY7QAEBaqMDISLIAofc tCB6QAuasIkeBBPUcA5cUAYswWXaQQxNUAQeIQdN9hGxwHnZEAYgUTV/8AJ/ABOHgAkpQAHV5Aey UA9+QAUckLY2qws5uwb4gAtWQAGJ5A4qQA+WoJfugACgIkf+iSHLEAPdVhBdIz0IQQLJsFEFUVO6 0GpP0AbY0AZu8FS6YAL6EACX9XEC4QWYwKBysgEaqaubqhPaKgeCgCVy9geBgAAiQARgEA2KsAIo pguNoDQCgQ0HgCEkdQDB/5ANwiAQRSAFHlATHsAiOIBcwsIHODAQCDAKt6ALfIAJh6AAAEAFOFAK bjABE5EGaoBcAkEMnHAAA9AGY4AMgUCwC9EqpDgQO8AJ1iAQVHAIxqULM1AC+7ABeAAGp4AK7ABl BSE2A1EFFcYQi4BEB8EO9DAIfqAOnGAGVGGEjmoQS7AKuvAJhwAROKoLiFAKAuG+uvAECsUQbAC7 AwGHcrAI7uUTPZILEnAOUyAQj4AHCSAwMKUQGFYAemAAJ4CqVFAKX1EQhCAMt/UTwUUIAeAGlADE R6gMcqAFlOAF0YAQG+AF82sZKXAGJ/wvyCgQTPAIM6BAbDAAQ6ULy6APYv9wCYqwDnywBQRhAzDx DtpLEJnQCeHADXMCCvgQA8kSHiHhB1YACvLpE17AXvGwDDusLB4EmLqgo7qwDVEAkOB3CRIwAQHA C/IwDBsmGx+CIuwTCjXwALlnA6EgCzwwBE8wPpA8EOIgC5eACbsgAXEgARLAAwTQDY8AEn8jM7qQ CKnwCXbgIboQCq5AEKrwBQQgC8sgYt6QDMjQBlgQBh2yAQOgB2ZpFewAxH/QaCbgBGpwAe41EmCQ DcHgCZMgAfuHCmDQECPyumCrE/pQDZJQDdR8ChOwC6cwyzYABAiwBfLGPn/wBLxwCS+SAEYpgJCZ DOrQB8cQCcsQAMiAAcf/EAtYIAG44AmIsA4lIAuvMAV4BQRrIAIikAx9IDLqcA0GagJHTQmXQA5V gA2WpQu5UQGE0AR4oCMdsQXWsAE5AAUC0QnLIGcCcQ1TLRCoV00bMA8jIA5IFQWBcAwLYBVytgGI sGu64AYl8AnIEHQ4ExKJMjUykHUemi5gJ4ChIDBiJzD6tQCJXXa6MASn8ANLsA5hIA60AAe/AAzD MATWAA3JMA8kYALQMAIbIAoTEA1ugAn4EAfVgAvhogs40NUmcM7HhEYIUDcwgQb98AFhkA3UgAtE IAu0MA/CMAmoEA2t8AZYoAjYPGU1/BBTgANC8B44gUrkIAGckLspEgoh/93PyediMQMNuBAMTXAL 4QAI3KDe4xB2n6AHJqB8ohDfyycQvN0PR+B4RVsB6ZQ9IBAJzSkHvLAO0GAqFtAIOCIvpLkFwDAJ BJAL5qkjb3d9/bAHTyEHD/AAY8AEkbAHe4AEiOAGM5AJmSAG2DAE1uyZtwAGCyAKN8ANYLcBzrAD nXAMnZAMYqAI8mANa7AHkaALKPAISiBETWY2oHs03g04J5gAAh4H66ALauoIIuANwod7NpAAFkAL 5QAIL54ADUAGVRAMopOBBHFAJYE5R6sXOuIKJGNE7xACfdBxdnAMHMAAPM4Ax2AHoIIBttAHm5A/ roAjtwYALmANAEACdv8wDSNgAAHAB44uA2nwAns8CnuQDBjQCjPQCJ2QBjQGY3uzBYC9ZOz2MoPx BDrBDR9wzvaSI9vAfSXY6usjgI0ADPPzB5nAATpA5YIyPtzQ6UqOB+HAPiQQDVhQAQlwYn/8usdQ AAwgPTTQQX85QSfRwwKhIG9WrQKBSsm+7QURAJ6sVVUCRywCtwfyAEWwNFJwEkWAJMF1mTQLME3M 7aaIh3D77M8uR8+OkktTBC48EJWADLXQKhvgS2wDMK7xGvxgD/LO7Y9xSNFIATTAM71gC3ngTgYi EE/QD89wIhhwSgKhDofuBxHQAlBCA6agCSwwWB1QCee48H1YBIPoGZ3/8fDTkRtNKxVy8ATloA4E pkobkAeGkBEUwBvpMBl0MCG1UAvC4fLI6BxGT7UPUAtHgAaCUB6VBAxAU7OKJRA2sAOMoBPSoAmJ ZQnEaA8OkA7gsLNqwbxMb4p0IRc4WwjpUAiWIAgagAaMsAcqAALvoK/aRjbuUAeXUx43Zb7uAAfW UBMsMIptf4x2bw/ni/YcUAvV4bPXWgFFQiaMIDtu4wc7MAr3oFtAsAlD7wG74QDgoAFlMTGNX4p2 OBlxQQd2uLmHoAlb2Q996QAeoA4VD0cpCUsIMAKdyzNCAA48MwiLnw7psPSt34eD8Bid8RiDYAh0 4AeCMAg1nxfSARWF/yImCIABtpk1rHBOPiVLdFALhlALGmAPD9z8SFgLU4v2i9ALGoD9jCANEcAK A2RBlgQWWfABAFGBhB8/yOQgO9JLWxaGWRg5KCYkAjhja7TpwphR40aOHT1+BBlS5MiQyPxoW6SN RTo62qREKEQhJQ0/JGwi27BBjhyMO5Eh68JTDkFtRcqUWVTGKFJkJJ0+FfkK6lSqVTdUxZq1I6Rz uXoQIuGqAis/CEho+/kHxCEScq52RPBT184th+6wGuhqUxYS5S4J0RXjnC4lYzagQYbAVjJGfDcS NHhVJzKbHu65UGPyJA1tKGnQYWFq0EUgPThw1bXQUouBflhlQayLxP9Pndvaohm47UFTXXo4uCOB IJTbgwfbaty2rUaFdyB+4cyy7aDJ4DY3DBv2zlAWXQlGXdO5U04oV8gC/RlQTE4WsySySA5/UBU9 OS40YCxSa+QGZGM0+VHjk1sMUI8CCrTZbJFFrkIGQRpmy4IGk9zKCSOGNpDGkvyakoOEjHjT6Ko/ OskJjxps4imjCtCoIAtk3vmgkS2S+MQZBDaApRw//sDpqicMkuOPjDZAwIYp6mHnllZWqSeUNBoJ JIVcVMEIjX5oAw6jGt4L4QoPPXIlEkbGAIKODbIIhAokheGBh1NgGcMQQ1goio65KCuiR52uaouV jawhxw+MyAFAoz3/uNOFNwQU4KQY2QwyaKNG3mlELFe22GacSxSgEEgTIsVIDAHuuaoNPOZ65JZ3 /mhEOAQQ2KaRFh3iyQ93qHsnk6b2mMcESj7UhRgDQhmJp1EwSeUTGcpItMGLdNnzLYwqUOAeLUHE KJ9WKCG2oy0IGQBRyZq4pqmc7tAojXfSQOKXCirAVLiDRPgE2iHfuqacuaJt4orhSPgjFCDUqZS9 LAbAQjYS3unkBQ/RQCPRjaDRQxfhMNogjXEEvcqANTbqcLacfmoQI2tBWsIHXZpow6MneMpHWmRC 2OQXO3qksFlpdbHgl1+QsKMRCyxwpVIbLDgilBxWqbgjZ7zIqQ1z/8xN1AQbfonrD7NCYeWqZwgB oqYiOgKxwpHa0gkbRfSBlj/KtNkZbgTQ3ejLkJaRx245tmnqjyM8lAMBEWChIIBLNPL5nSOOgLGY Z2xoZJtQ/kgggT9+SfEptA2ajYRQpNPFDwqeoSxEe0GSyyddRtgkFJMg1YaOm3466S3JQGFGkdMP 6sgLdjiKZ4GNNsDDBBOo+GMnaAPXJCMvUrHjg1+OSCMNQpAABolGuPnjUyAzytwj3t0Wzy2bMJrN D8XhIw+Bg57Y+YlPwYe7RCsSnY0yEvBqqbNFPBwGAzCAAPT9wWwYIwQbMnK+jDQhANiCC4iMoxFX ZOIBD5CG9GxQPf8b2OAdSNhC9/4wjiQMJy6hCKEJtmC5bZigCocIxatCEQoTFEMQ7KlBDfjUIDk0 QBVrSAfpUNSIYdyiE+9oSgKsIJ15qGNscymONogxgAqUQgiaIMYQqMCOMHBCCR7KiaDgYIBnoQ8L ihBSR3LAo+FZ4A52wxgrfkIC/sBxBikAQzkGIIMPWCANfuTGFjoYSG7YgBvqUIEcrGaDLWyBGwkA RA4sYLw/NJKRNnCFDSpQA1f0Q1DAycIhCFGOcsjAFS6IQD9UUQAlzMWVIbuTW14FNxLAoy0NOkI5 ZsEIPRzif2WgAbTawrtABAJaT+gWRpCRhhcZc0gduUUYhokTZUz/4USU8cM2NCI9WUXCDb9oRBo+ kAZGChIQ15jANrpnvFBYgBvISMAScLCNFXKjkNywABtgAYtuCIMeqlicoCjAil7Q5CDbwIA6AuGK gmygVTPECQPSca+daKIY7dCFL4owFFZcQAbqUJDo2IGNueSPJwDjHE7alhPJtOJ3IbKHJcZxgbiQ zCY2qQkJtvEEOL6jH5+Qxjve4QpOMm4TOChGIxjXiH7swQ7waiQS8EALFTRSkFcDp88+0I9+fEAa oyjGB0qxAXdYwgMwoYGB6MCII0TAHax462voODJQTcYkDxqITYpQEGQUYRE0KMIh6KEwBEEqr7C5 6RFk4AM8MIIR/1agApA6BKQ95aAbPkBLIz4BoSxog4G6oEUPugKADZzFEmrInE+y4JPJdM4dDzqJ NtDACm2wglm5qEYczsEJAKyhHsKAhS68EgMq5bQfq0iBHMWDDFfQYgCcQ4AV3HCGbhBgCPzZGRTD pwt2uEEXBTBNLvjgBzqYwhRFMJBMKCAIQxShBtqQQx72gIws+CELY0EQQfygiQvwZ7kkOBFLNZKi DrlmNr34HntA4QZ3HMRtNs0vKxihX1Z0QhoHEMYqJjCGe9xDEA/KU2chhoYsbKkG7iiLJQqrv5rI gRYpqIYkmJGC/yCjAhSI1s4mgxEH1KISHegAHejgASn0Ag3zYf9FBXrhAVNkoQ8FMMaZCHKiB8Dg LkdwAgf4wwhIQaq0/QgfUeqLgPripALbfYwCxOCEoURYGwFgxiUoQII1tIQRcICDJgYxiI1KwbMk wMAA1MCAEgjADzWwBFHZcQZ0jAInHdqGH14wDFgowjAU2oEb2HET8eREeboQhAMGIQUpUIAG7vCA JSxhZBYRtQbbYASsa0DmbUSHFWShzb1KS1mLYUsG10gALQIgA7ecbiMIGAcdZdMINjAiPK0lwSc4 UY5DDCAFk8iAJFipCgUc4kx86YciIFEMMjfimpSh7x/yx1JXtAIPCHAGOuIwCUp0egboiIb72pI/ jITazxq4hwr/hLAGHXAiBmqAzTZYMWtkqOIHliCIe+JCBR1sYA/T0DVG/lADj9SazPxxBQJqED5g JCMTIdqCDjHWlpyaxb4LobA25iCAEgwAigNBBis4MAZ4BCMbnEjUDB+hBHE8iicbeMIAMQafHEMr MQh6iyAEQQF9XOIS96CDkd3hDkbIIRdKoMIFqINTBAhKF6vggQTQ8YlNZK4KGYgBSDbQh0gMEIjK xNgL1BCicWgTI7Qgwg5sA61+RGAHMZAEPhiwBheoIAJ5kIYU6GAFHSizLJpBQCpSgTEYBILpj3hD NrqBiW6sAwPC44gfmOVKXcwAEwrICB0EIeQINBwX9WCEAqiw/7pzsA0nlJHMAXaBCiKggxno8EJV 5LCHD9xhu86AgCrEsQwIKGAHeojGKoKBCiVkwoJHsMMFy67sPTDA2HU0O09cwAcKiO/TGXmBMRTh XZ10ZAOTIIDKPs2EFNQDP0KWgiJgBQ+QI7x4gCMghmXQhTrgMipYgR24H6cYhgzIhY/Ygj2oARko hyfQhWXgg7nwAlBIEWdgh+fqCKFQhkPYO41Ahj5ong2ogkvgAHVQgwBIFHOYhHpQBrOTimPjCGJI I1voBKzgB34QskGggYOggc6ynakYhxggglughTHgiGLLCFrghE84AB65gCgohwqRliZompCog0E4 wWcoKY5Ih/8vCQVZmASS0gqOKAOMogD3kRZ6oIeFwAH3WZ4e0QgaMASRAAGMcAREoQpsWAUwIINU sAI++ECNMAFCyC7C+IIKJAEqkAUxKAWMyggmuIcOeDSr0IV8iARlIoaX0oVbiAaOIAUroARMwASe 4JCMGAV2eLTJEA+Q2Dms6BCNcIZtuAocEANie4qcUAZnChH6GoYYWIMIKIZP8AEq0AJOMAaoKKOP qKSQ2AAqCJ+KoQxNmIUGmURji0PW0whBqYELuImRWAdq8BOQmI6dkQNYgIRcmChd8ASP8IJg0IEZ WIczwAII8ghlWEGMGIZd8L+P8AEFQAYa2ACB04hyoMJyHAn/fdCHa4gBK+SICkCGcDA/j4iCq4CD PvgQ3nEFR5EN1MKYXCgAcnwKgdQIDpAHMVibj/CDDeCDViIZgugs9/izm8IJvJij4KiBMxCAoSKP LXCFpbyqLWgEDGiEZNIFR0SEXOiHCviDZGCABogEa1iCMbS/nEgjXUAhYECGJ/gFkCkHu9GCS/hA /ogCvtkIJDiHOEBFj3gLL6iCjEAEZeAIWngEPSgFXbiGAjgHBngdV3iuvLIOOMAEZlCZmxKO4NgG BGiAccCURqqkDrIBdRKkNMCAMYSCCUiBFGAHDOAbvnmLZFgCL6AFAyAgUQgBc3kHDjzBNMgISiCH FNDLVtiB/4w4CY70NHPJrlCYAU9IgEnMh3zQhQMQgFMYBixIAUqghCcIAiyIu7ODw0TxLD+IhltY gbmwgmh4hPpbhh6ohtz6gmrIAFs0iw2wBkXAB2Y4A074mRVaoRzgBjlIgEKygQTQiB0YAdvYAFHQ h1ZaAgJABRnYgAdYA2ighWQKhUwYS7MpUF1AghRZglEgIE4oAHEgHl2gLZLJgguIGI4YhgCIBWtY AzjgjScgBVoAA4zRhWh4g1XYBVwIA3NYh1vwCAwIhuTTNabLHDGIg2pYTx8AAmu4ESAwhhWgDGSi HBNIAENipP78A0fQiE3KAhGgLgJAB1xIz2pgBl6YACpYgP8lSQFsEAUM2AJA2IEKyAg8aJlXeINd CAZmyE5hYAYBSIVbeAu8qIm32JsJqIcNsIAEUJ5OUCA5mATIzJaziwMewAWz0wURkAEfzQgwIIAU +BCBJAV5iIYAQAVQCMlxVIFV2LsnsAYlQAAqdR3jeYJG6ARCOIMAyAcqHUtdqIFGiJE0iARnUIIJ wIIS4AReYAZmkIBgWIA1qIIA0BeMsAWN6ASWEQWO4AZd2L5uwAd82DwDaQ/bMLtOuIC5mIKdQIRr 0AU8iIJIgABZWIVVcIOrEAGQ8IQDsD+OmKu3CAVNBYZdEIY7qQBXuApywIfVkp8nkB/jqRxRGAdQ IAYyuAX/EAEEaHgEclCEC0CCZICDTAihCcgGHoiDOCiBS0i7L8CH7UOHSTCH4Tk6X4mFndiASLAC BGgERtC4GjiCytwCnACPfEgEUBAHTMgGdAiCBIAGadWHX9kCKHAGlMnHjNgBQFi6EEECTKiGH/iV nvgJ8wkFA8AFN4EHd0oA4xGFsjWBSmJYUWDbPzhbE9AIiXOFP7AGNkAAV/ijkFMOBHgCZ5CBZZiB JZiESSCCbCgBWZCFGWgFCDgGJcCHDDgFAqhEOJCDI+DJrhFRaRgBRMACUNiBSOAAPJADeaAGLHiD W2iCFMgGSegBeqg/jGiFSdDUkMgHANUFqaCEyIgUYoGo/5dRJBFKAEfaIBtAAiI4ADwghBUCBG4w gTbABgjYAxMAhHDgBhSAJBuAW4yYgmWAgw/IhDxIgxU5goFNuW1YSldAAgM4BTFIA2DYgpu5CnHA h2qQgHXQhzZwGFhxBeVwhbayg67ThU14gHf4hQtwBTk4AHNABWaIAwkgAGEgA3z4gmzYBQHwLhM4 oBBxhYxwhibIlmu91p5AEZmtmj8ImFAo2xHAg1CgBSwIgQQYGkG6BF5ogAQQBVtA3BmAJG4YBzxI gCm4hf58JI2wg1SyBPBjnE3KAw6wA7x9l35YBk7AgQ3YgoHd3z94B7OQAwjIAGaoh6EoiFDAADbo BwzQhP9n8IM2+AF16IdfiBFpwAIFOBobwAE3EINUgIQvwIVTEICEKTY5SEuMQTONaIVE4AR9SBh0 65wZmhwTDl5D0oUQwAVZkANDsgBbYCQLyIPKORrhHSRASIBWEAZCCF7m1Ygj+AA7QIN3YLV32SSx +IAPQIAQOIZ1+AF3MF+PSw4/+IUI2IAYwAJZIAcD2ICBrYAjcJcPsITV4io6UAF6KBrsAQaC4QYg MAcBQIVUAIJ5CIAUAIYO2oLJ0Z7segFZAB94GEXesZhyuymdqiSltBwRQId5tYGz9M9GWt7+BGV7 cmRugE8/lQNSIIJoOJWMqIFeYIQcUujoWA6FZo5+2Ib/PiiHRGiFLKYdErCeHTCASxCDBki5UBCB ZbCGEaCFXQiDzqCCc/gC3aqCeZiUn4EGDriCBjCGT0gDW5iHHLiGK0iDuTVhZOieq7gGXgCA2nXR JyCGeJhEWKlMGUIAE66k4A0FRCDPykGGNogGeDHhtE0AUvCGEOqeyqmnNriFR2DYXZ2KcaRIcrTN tXZrt1brt5ZruY7rubbru8YIxKtAbaCJs+hOnPOv7JIDQdAxvPyQusbrxI7DZZCEc5CEKV4EvpID OxCEMjAfMOqHFjgCFaCJm3TZSWStQVbs0daKtsAxOZC8nfAD4tCfm9kXXbgLjHDjunGl8JCLDYAM 0tZt/4pUEBqgiaJgOc2YDTlwCWRgAXsggTKYDQqIgHekg3YggVthKcogMGTgB3vY7ezOCgo4CpkA Jr4+CYIgC/dAt49g7X0zrM5IH1DR7vZ+ijKggK3rblODg14oAkuwDa96hswpLe5Ahk64xyugQm2o MT9IK98ugnZQcJh07wbnCDqIgBYoAvQytdewBA2Ag2nIr8jYAL3YCRWAARa8AHfYAFYogs7QBiHQ ABYowg7gh2By8Bj3CDoAhwh4hnQohF4oA3cApi35X4agjZwLn0ZwPmh5B+DQBgNBiXaYcH4YBHtI ByOQ8SnfiCLwgCv3ADoIQFYYKEaggCx4jbgIHHUYAf+V44jScgf0KgM6sAcNoIMioIMi5IcOuEYq l3ErFzIPgPNCCKJe6IV3SWglkxYG4g+NeId0oAAhE7IJBw0pYPEXt3M7z3JFz3JBsAc6kDDHYgRt AAYViDRBTpFrGAVN8BAHSIcktwR3YPNa4HN+gHNIj/QpLwIHcABSq3U47wU6qIWBRYIQ+AA/YIRC CKYmRAY0OLq5oIB+KAZ7yHIr7wUKyHU6WIRYn/IslwKpo4N0AKKsWxGygIcLgIdnkIzTcYUPwIhA GIV7OAnHcoclkwJD0IBakIJBYAEYp3YHlwZwsAfJkzwHEIRecAc0eK0sEARLQAwMcQEp+JKBgJYZ qIf/WSiCFnj2CZ/wMugFJ0gHeufEe29wRtfydIABDRgENDiCgE9oO3iG9pgrZOiF1aYQd2gBaXgN jKcAimf0FhCEQdh4jm9vOKd0OPcATYgAnYUNBpgGZKAAZPgFxLApbJqyPeA6mF8DD6AAKUgHkR+E dOAHnm9wIWMBKZCGdJjwTViDewCCYmAEANsSNGAEaXAAFyGZt4GMFqCDLJgzRqizNNf1eN95rt9t PtNyQWCBIhAEGMB0GqgBRjAyg3+rLbGv9nhqNUCAN88CrmMELn9zOoD3dLAHe+gAv2/vN4fzCZ+9 WqATIpOwdr/810CQsisLBJAGF2CE9mCEClD8TYiF/0JQimy3B1gH/d2WgvNKh3Qog2fQgF64tU04 dRrQdMf68iyYnoFgj4jLgrVaONq6AycYAFUoBicIgzWw1N8n7XbQAAfwgFr4KxZwgL2SMORfiD/b ibOAmOGGFkuQnZNwhGG4B1YQMn5gARYACA0s5OgqaPAgwoQKFzJs6PAhRIfayrRbRGNRO23u6OxJ J4gCK3es/JCQgyxLhXdZCg6yl6WXH11y/Phh1KJWkTI66RRp1w5ZxKBChxItahAZSW3aWnZYtIik HxpK3dHYMBPlEZMbSJTcY62ITJoaixShUIQOz3YEjbJt6zYoCWRckdGVS5OrH2QmWaWTImdFl5gG 1//qcleGRYQIZeoUokHCTwepiwi/raxLnBIlskoMqFGhAolQJevKKZ1wAzY9pTfo0tRCl1xWcjas +oEMQZaSlAq2WVYOtkzKEUtuoKBXGwUPefPi5aqUoB9EEPRsZcVIZGk5celuYL2Vta4NJuSM+42G eLkL4WeTAAAufPeDuSRlOEfiV5oPR1KC9oPgTxr3ZLFFKFYllN16eMDyS24kILBDBJYgck4MusRw ji58cMDabBuEoo1WB5kElFXZ6VUBIXpo4hgJStFwURlk0TEIDboA0QM4uWBIAQWWaICMNlmMxFVc cY0oxyYjtJBXJ6xsQJJe4JlEUolAGRRDDxlAQkL/FllsgwBNpJ30R4EJyYVQd8jU8M55CNjwDlcI oAGUOD2c04MTaPRSAyudaBLeQ91pp01eG2hCwZQuSnUYC/xoo0sn9PWAwwbwZAGVHzMh8MEOKpRE 0AZpdJeFoMcAJUcI99wl12oFnWnQpf7VgMQvXG6z3YihiCYHMV5s8EFM3nU3rFwkJMBNOXuwgkCQ fpB6kB8tFCGHNBUw8FtBNT5UWhZIzcLOGCRsoA0NrCjl4mS6ZAqbH9oUU4h2q+klBwKnstaHASTA ZgcGf1yATHwFDYvmBb0cVAPCNbhSARKOIKDLFLe4ikC9VqIhTRalbcMAB650iEwojSyAhzJYcLJN /wXdPibwsBvU0EcfdGgHmyCCNRTILaBwwk4ZegxwwCn0jFsEoeRiBBSQJJz3WLzgibsBwFDL8YyV 2+qSjyrpyICDB/AdVAEj29TQZRq3zjDJG26IAwE7v4SCQJlrlRneNmmQQMoZE3hySyoCcBJIBQgk oogxGOjCCCMAy/GsLnYgsYEroTBkoC7D7EyPGn6MMYEBSpyxyigDDKBJHRTQ0EEZunCVhRSKl1ha lIDq8kI0VsrCzkHyKIHQNT+U4ipBrRpkwQdoIAGEC5/ZYIMFrmxjgzlUmBC7Lk+YwFoCa3VnAh7Y YPMIE6n4QMYA27hyB5G6UPBMDZlyKLAuSWQC3v9RBjXSByOs6KvLBQPoQAMELrGLbKBjFZ8ow2MW UYaYwK5QoJqJOwxCP11IDiGh+ANCbEAYDswCNtyiy0HeIUI0DOgPrmjAKpqAACPVRS+uekUbZkOL AqQAAda7RTkAYYXAbWMLH2hEBbZhPtagwQ+sWBYw/kCQTuzhIPRTYkOQYQU+FEMXt1jFAdjBjnqs oSR+SJdWDOSdWCigIKHYBlFE8IOHSRB2q0GjQVLyjhqI7UtHDMX1SvQEUTwBYAUJADlo0YoznEIX JsBGNyagi2384VKNREn7ssAI1qipW7lxAcCA0QARLAMaktsAApqwjP1BZBZOUIMaDuEduwjMZq7/ 2kpDRDEKPLARIZ5wg+wGIzqZEOESETRIGt7RCFe4Yphwq5dJHmECNFGwICkQRhu2UJAEmGMLZPoD IxvQgAo0ogaM8FJBaPIBRhTkD9YAGJcawZr8eM0gL7iG9vCQBW0ALErIYAXRGvgoXcDBlQl5xSNy iSZuIMQRcsjHgRDAGhJsAmoHsUAakJAGINrAeQhoxDbyUYE0RAA89JPDKHYQnvHko6TjAEYjHPQ2 V2xhG11CxhCooS5kuKMTI5CGNAqBwYQAwQl/QMYvFqcLV9DKOU6AgSaMMBv4rMwqcqna5HQxiwtM AwIzMIgoFCKNPyHENO4oAg06ZJUJNkKYv/gh/zFZagFukKJA5YjGFB6CjTOQEhkWsEEjQlEBO2zj bXBEAxosYZojsuVUxRqWikg0IlJ+FKpOdCxCmkAGwkCBFKzJAbZmlo8sIIAKB/nALyT6gTTgR6IV 3YI0XLGBjC1kCuZwhkfjIwdsxuVtRVKoLvrBAAb4wRL2EI7q4PgLeEBEFSoIziHIIYTtFEkb7/Oj HNyxhjUYxA90iIgjGAKq8JTDCXLYwRgOclZ6cOAdaUhDJvpx1xrcJgE2eMIED6SQDZCpLmCSSwUI wogP7GEN12WIHw+CgC3ck3IbgMF1+wCD2UihHVYp0spgY6VQYEMLB9kCAihTwYOIIgB6uJpCTP+Q g3BgkEPUK8h5aWWBXwAjD6RthA3GsYUtlKYGwN3WbGBXl/35gQKMcAV7rUKS4AHBcPOFHWtC4AIw dSvHfiBLmB7jT12oIwbWgE98DZKDSQgAW1htrByUMIxW6MM7AqtABMT7AVqxWKIWgCgGMNDXUMzL zBLM8rBMomekQKUgXOmFE3hLAlew4gnQUENBbKAvyh0kDcCwhMGg5p3FasMSmSJSSXRBhQcyJAHO OIgXsBHV4HS1IDkmDChKcARa0SoS9cAARG3AjVvYwAR91LEuaJGChcz2D6/TRpEIDEVg5+VV8OvF Pg+SjxwgwSBcERgE6KEqvZCAAu5gRDnqMBf/OtSoFIy4QD+OQAI79IMR/mT0tA6iggAgYwkGyHJB npG6B4MQmHZ4QASAsWY7HOEdzbMBGxJAplDYoBwVKIgrCDEOUeRjNiYYh0JnKxfR/KEYvXDFDtRR Az8jhZR7XtcUAOY81kzPzwIziZfScbrbxMIdclAAuBSgh3uQSBf2GMQTDlEjk8AGDFioJULyAW8o HNxVOzgCMn6LjCPQwR0rKQgxVKGOTIAWPzL4xC9knQD8CNwCo2CDHJ6gxCeINT4moAYOkGE+IG/j GZbo0mdYA2wEjIMPxggvbLYRvFsYYBOvkEF35gEwPOzAYFbKiy6GIAtkXKAQahiCPrQgi3oI/yMX 95AJLBFQRYTUQAqTBt4iAwFZ7hyFFbBhITK6ZpBifiAPA9ADjBtx1jRsgaXcuH0CTDCEGJDABjmw gAnwaAJbV/QdJqg9MRGW/AoASxctQAMCYkCPWMzgAIF7xx5kgQtIUIEEWwgWe+sFnlAAww8bOEIv uMKKLBQBDRUYgDz0EZdeIHqsMhH3yennoQYQgh7HleBpEAbU7BjCZIE7QBUqxMEpsAG5IUEjNMJd ccMWLA83JIAF5p5JkMDwXZANoAAh5IAocIMFAIO+IcEFMI8NVIDCVIDccQUa5EExTAMyIAE5GUQf jAM3yMF4tMypbJdVlMMjkAQJMIIazIIyDP9AMbzIIpAIaeiCPvBBeOABGayAiMCbQlyDPmSMaSSC MdyFH9QAohnEeYhQI+gBB1QAXjVCBW6BBMaYwAWfruReKMjBEogBHigAIVTgsdhAGrgBGQQDERDB OriDx7QGDayQkzlCIDwMhgnRAD6MMtQg/OjCPXBAGShADPjAIrSIuXQBHbSLHxgBA83LHahAL5QI EvyJC8nOBgjdJLqMXrAK7GAabjyGSx3EEXzAO/wCCOzBL7xDLt4VS9lAelnDPPzB8b3NFgBDDuwA CETAB3ADCi5PI4DANOwALNSDJYQCaa2ENjDCMxCKH2xDIFxAOWTCaNBFf/wBCcCEs1nFpRz/oKs4 Ry/cgxooRRmoQT1ggeoYSWm4wj2YW1wIYasQBCEMQGwNIE1kx0zYQAJQQiCQxIBMAO6s3jtgwAW4 wjsU02cgQSCggg9swwNugQsAQyb8ggX+QQIMgz5sAiDcnjT+wi/Inr4dgUyqwQD0QyPEhDawQgW4 AKTtAQAUwzZYgjQwQj8szdNox3YMRrsgRRHkBbnMBTIs0EUUgQ7IBDL0Qgt8Yg2UxKfMhRxQwSeI y2zUWXBwyIh4widkwTuwAQ4wAFJIUoBVYUOM1YPl2PtsxbwwpFaEiKBoheKoS2AeSYkEjNWIyJ1J iUNImrNFQSlkyiNYGAB6FGx8QgfBhmp4/1BCpEAP2AkfbIBUEIpdmIQ7BNmOAYkCKEASikVIlIFh 1IgiCEA24AIuuAEs+AAnfBiWnEMBUIFcoMQFYEBeMOQ2EIPoOUgghEEJEEA3CEM9sOJ6EIednQEB 6AID3EkPGAMNlIUCUYAC6YRZmIuaxADvZQEFfCManMs3uoEP6AUrzAldnNoEncM55AIDzIQfoAEc 3AE9IR7UROWnaAdJsIJj0ARKeIA7aIMHaIMBTEIGUMMtoEUHwAIt6MJ8FIAqyAGwPcYwuAGhfApd DNl8kgAsYMIp8EAJPMKcTOJpbEUzYGgGWEMPFIAceMAgDAJP5EQRsAIFmAId3IElsAJd9P+kJDFC kOBGDRCKicxnFjzDNCBmQSQDDuCACswEBeQFI1RAIGCAEowAxNACGpxcXTgLppTDGLRAT0oDHKTA KaDCOmiCFBQBC9BAIEBDMrCCJfzCNuQPIzQC+hHKL9RAxWyHXtACEaACD8QBKgwAtUWNiwZmQVSC BvCBKsAAWRSBBxRBLxRDMVwHK2gA5owBJhgDh/YkTDDCGtxDP2yCExyCP5KGVTyAY9EEVHSJSWwc nRbEOwRCL5xaaSAAez2GUnSJc2jDHmjCLIzBIbADNkTDOmiAYxzBPBGKuWRBDbjDnqhgmMznM/hF XIgDMzADDxABAjBC7fXgakhJvOhCLdT/wiAIAgvQgQd4QC/QwSbIABP0Qi+Azbma3waYC6FwFuIU ETJUgA8MgDvUQiz2peq4UrsESRbYwKUo1BGMqYt6kBrwQjVgAXO0iCW4wzWQwxD4QQWswViwQwlw ghoYglp4wEhoAxrcgRqgARVYwWPs1Q+cAS1QgX9kCjLUHjTggCxMAiiUwW2AFCqU0WqsK8/pgink qANIAVpYgiXYgRQ8wzP0G5t8BiMkTJeMzfqNI3u5gAaoTpQMYJTIwREcBFe4QzhuA5U41F2an3bs 2BG9VT0YRzIcFytISxFEbVj1BzIMgzAYgiaQAzmkAxrYwWMggxgIACg4yYggAyJwggoU/2eOZQEx gcmACoqVCEK80gE0QEI9xCdyAFYFAFYBChFnjc2lZMHbUdv+tAygdIfeIcQ2jMBGJsEDiItAAY9o TBgjEEl2EIkR9cIFzEI0CEAG5AIRBEMKwMInqMtjIMEqpALN1d5i9aVf6gIGqIMJbAMyrMI6UIdT 6cUFlIlTmYYuCAL8FoET1MMIsIEuGAMkuEEvoIQKrl8WAIECSFmc1AsFyUMuUOGpnBzwxlcyqME8 yIIYqIOUIsQfNAIbQU2mjVWxIIMsFAAD0EE5qIMMKMAl4IMPkADRsMtjbAIMxGzG3AZXlMMqAGIr 0KcMEINowIKiroIaGIg5EAARqIEVKP8AiNSbFNSCJgztTDACDKwBOZwC/17Kl+ynGujPY6wQMiiB APwfM+kCCGjAjXHJL4ypH4kGQpjAHrjCQYRCIfrZX9aE0zmLlCHDKJyDEiiF6tQYGoxCPdBBFhBD NESkSk5BAXxBNjBBw7UMFdjYYLAMh4wLBWhC4pjGIDiAA5xDNRTACvjkN/UkCRhDPehBA3iu+nEF yWkBGUQDHhBC1byCIshCQ8xAIjCIlTTADsDRBmSCC7gAQkjROwyGHNAZCbDBnJDEN7FC+4AiBthm eLGHpG1CIWABOkgAP8bHBtgAmNKLFYyCOZCBG8QinZUGnUXNUoVFu7CGFEjBAzBAM9T/gTskh/td CpdcQOVyBwiRABlkwxfEgQRIDGysghjw0045kUGEQjEEQiT8gjEIQf0aQC4smSd8WBebGjJY8Fct QgXowy6gQvU622OMpmepCyObxB8wq0HggBqsLTeYABYQEC6cgaM60Vrckx94QOoQtC5IgSAUwTSA gx/sAM9oAi0MAEmkwhAEx6npghsIQD2sAgFIAjNUgVHUwBQcQrIpRDg4QgNYwRMcQBMYhCLgg3qA Rz/sTwxIgip0xFHyiKbCgUQfDgLoHV28qdSw4hmtggSUQDBgwirAgi40gjRpl3OlQgYogkEUgSCg xSf2QS4EgC5cii6owjnswzwWRBRU/0EUNK8wBEM3TMI6GMUGdIITDABlBKwuEAMO6MIrkIEVyAEe eIEcJIDqKFs/QNUy9HBsyUEHdMBBmIA1FIgVxhclkAERcAIVzrTbdgNIrnEKSAAmFMRZeAAd9IJI IEMETENc9IEKHBcJVMA4kMMPgMIPAEBC5G5CRAMqnEFDZMEm1GVBWIM+AMATcMMCDMAoHAM5nAMB KMI58EEeSEOmlPZaAIB6rMdW0ISpPQQydI8hkQcDQEMU3IInXI0VckIJrIB2SAkpncVZlIG1iSMa PIMukEMwnETwJEQiyMNDAAFkGcQTzIMrWAGHxAMkVAgltEENtgEYgEEUQMCVMQQjOP8AQqhcQZCB AAhN7cJCN7BD1bhvQSDCAQCdLjhDE2yAARz1XTYEBeg0HdxDMSgFcyAF2kZRlikB7jyCMiR49UxB XBoEIHTC21TjFYxCdzxBGzRByEGEHAQC4MSXDKQAB4THLWDDLBiCO8hAQSiDDtDFw0RDN2RlY6p2 ObU4RFgBC7QDHbBCKYBIi7h3QjSPQ5wBJ8xCZjaEF4ACLTwCUIhCE8xAFIwBDNAPKBwApR+EIFy1 TNyDAxgMDZRBfO2AcW9AK6ACEYT0QgTCROtCFCwEHZREIJRzQRzCPRCNNQTAns1n8DpEJvCBGHhB FNzYsYfCIVgJCcBRtveyTLNCOyz/RA2MKXAJByaEgamTgUPcmBVqwBpsgHbrQgOEAh0gLWQBFym9 RXdQQPWQATbIwSvIAjVUpEEsAScIBxX0eBvAhg6AQXRqQzuYAjLMwQB4QEZUghUmxMAbBDTAQXgM NESkAhlQklroglK4QBikgBWwjPYwxBAQwUHUelB4RxtEA+eIgyckA55CRABkADnM1BPIQDFsnMCg 0mDw/EOoVkFQAwF8ti7oQTBItQSxoC58wiEkRAyIARikAIeuzgqYn2VExFboywyQwS3MWCggu55H wSPEV6aBAh9AQ4YtUEEcACwLhbYkRCTkAh9YwxpAwwhsQgWw1BMgBCXowByAhwkY/74uLEIxdAdy IG1CdIISGPvaFwQVuILiqAHdN8R/RQQlGDsVBAMPnMIQFMONkYFUQ40MkGxEgIUueMLIKwQf0IO6 yIHphT6QF0JCbJwcuEKmQUQVuEHvG8SSHkQXQMIXVAMUQgQndIMXREQbTMIphKEueIEnUOZC6AAV OIU2TIAAQHrirYPUr70V1AM70B+uM0Qk9EFjWqEfhH0zyAF6LwRAmBNwRhcFdgaQ6VK4kGFDhibW IFAIhoiWhoYG+aFBwmFHjx9BhhSpK9aGkE9Mjlyog5JKlx3FsXvpUE5Chykblguly+QGnzgVyvGy k2GBc/p6aOvJMFQFBNzmfZRjZf9LRzlydMm5kBKNn4WQesx8KeMMOjccPSY8V0AXCbd+SPiRG1cu AribECEjgUwvgj8kIMjztuXPHxs2XNlo1OgwYRt/ihZY1qMOMjkbxBnAQW7CixA2PYZqxNOasYXI QjDcgABBDYYxwvI0CToouRL7RP5BhGkVT11PPq7yoUvJuXO52pK47Eeb27gkNsgAYnm1cxIIXBlu kmbbti1buB0+bGE8twsMGyDDsAGZbjULobxwBsCjnJ1YVSeQY+OdwxjWfKNEh7aQKUeHKvBjiB5O VNrAE2wUMoGDjkCJYqEdgqoJGVhSyIo9P5BBoht0SqBiobcQ6M4GC7wjLMUVCRP/IYVytrChgVsY MkcYRRQZhi/lKgAiCiVKWIWXAoqJ8AGskHkALYeAyUcUF6whZ5UDiJDnPYVIoABEErZBwLKONnAm QY9keGMYL065RJdX8tHFhIVeYUiOvRhJBUe+ygmGiEC80ueLOC7B5Ytq8EnDPr8SkiON9kh4III/ ErDABFsMuCA8GxJg6IIukPEjiwrSSMM3XZzBQgwxiMGjlVVG4Ymohja4TBdgGCIDlinauMWKBhTy oLltLpNDop8W2uCJBEJBaSE5uHHmN55E+MEKXfahBApgwQhDoSiAUyhUpQJ5ZCe+frpKF314OPSL QVFpjiN54jj0DAa4AcSELRLY/+KaWzitkZsndWGjkXcWA0aiTK4RowR5ZJATEXlyCQAaaBawlaZw dHlgoXhoOYQEbMxRyCRt4EIGgXmssNAhyBayJZL+FppTl3yIAUMhCC7xxIspQEKA4FotKxaZDfIh pwAB4jD0nE512SKfZFKIwoYFuDGBUn65sSCH8BL4oxWGdliCkwD0EcDeXSTYhYHWEMCpARP/COGP n3ySwwRsTpEFOFUMmEIic/DBQoYBdNGmaPywSxaZbcQowJhrG3rigF3OqEKXKohABxVUhFGIEqA7 yiIai+z0STafnojkEnziqLcaIlAhABZdhsEFgA3+MCEUv+b8g5sEmCXPZoXmOf+EAzdQyeZzAiRg Bhc35djClk+8ACUaWD55woR5QKsAK0rYxkWAQxSSRQwthJElIRLoGWCvlCLBhh1lnhjHBPx+wa+N aLJigidEIQUEwAUzFGEhcwQDQgypQjDIkCyNPWsh4TLJAoyBiWyg4xS64AUzXKAQfaBCDcsywQmf gAwBoEIEWIAFKRIgilnp4ggfAMEhBjAEXBDAgDyoRgYEsAsfOEMH0SDDnJTljGsspAGJIAIWEmGO aJyBAOfgQyyIwANmnCIFRBgCDRmRBeXgRAVj0IVeVIcBOCiEEyVgQla2wIlJMGMXLlsIJWRBC1Io ZAoH8ILjHLKMajAQDMwgwLP/8haKRukCAZcYTnv+0CzfCdA+abDBCY+nEDRU4ANI+EMaNgAJSUCi G7g4xSniQIBopAEI4pCFNaCRjEToQxWE2Mk4QHELrGCgHGh5BS1OUY0SEGES3dCFO8J4NOVg4HYj wMoGoDAnUWCAIU1IxCU2iI0GiAMk8fAIsjzyiglkwxMmscXR+GIZV8SAAOjwBB64EUlkTBI8CZgT BIawBVkw5B3vSEImjiGDCSyjCUtohTPoRQAskCMAAMADNDqxEBeYIE4h+IAuAJEDaS1kHDbYACYg AYYSrMMiaGBFFr4TiDSgZQ8TAkQ84vQHICCAA4dYAIZwtBBiNGQcDEnEOurk/5AppAAbJlEXImWT BTFMoCZyqMA2jvYOVcjBe39IISZFIUBadOMW2LgCwToxgicAAANyAEIs7rSFZUxCAjwoQRUEIr11 PCgVbmhFMhbAEOEhASudoKYuZPCJNuzAJqyoQCMwQAiP2uACWMHBPkwACljIABFAmAJ+oAGgX9DG IddQRG8UYgucmKQRy9BDFSZwBn0oAh1FTWdN/oAMRSYDehzYQB4umVXihWKS9jSBKEThPeIdbwNU GAI+zsCGNECjHPNIRjJwEIAfyIIXkFgHJJjxrkPFoQSPMMHwbLKBbfAEB9aQQ5gQUQ7vfMAno6jB EcI0XiKlwhywEIE5JoALXP94Ih4K0MUL+HAPD0HhFnFSyRMQYaGmQkdZeOAAPRSyBWG4gbdyiEQK 9GACYEBDCWFIAhQUEol8xVAO8ihBKIBLPOACAgXhupkL0ECCCrwjBCr4wDu20AhXfMcV23iCDEys CFxkIxu4gAQtSBeOqugiB0tQBA8EoARbZOII16mBH5TlgyFYYRzlCAQyxjEBWMgidK2IBiWGsYpJ ZEASuMCJM7DhiZaABAW6ALFsTLYB5YTiKipTJDLyAI9lFQYY4CFP3agxDExIgAAK+C4gnkAILJRE FKTgBnC5cemF5AMasgjAKMRAjliIIwSu+AUExPGObQCjE5HYQDL6oQsDvEH/GN3YRecEIItYdEIf uMgFGc6wDicgIwtHyIJcaoCVD1SgD/qQwCTIsAAO0IIJ+UUHEZrwBjCcoRqhM4Hq/rsKoNCEIbFQ hLfuhIAtYEUJuKiHLhQZilBE0ncJyDR5bMCNHCSCDJ64hSjsHUNsPOIJobC3DVIsCkBATRdeuMQE LDEPc1zgHcB4wAM2kYlMJAFhaUCCG4IBAV1YAA7qIAQeApDdOPBiTiaIxB+20J3uVMAOltjDA0yS iTyowBinUIA+wsALTGgbHcHQhQhOYUoJSOAWBV8Kuem0kBt0IipB2UtNxDsCEnjPBLJFoQn6hfCu WeAPOMgAPvZxbznkoxHE/+MGNqgA3N8CYngM2cQH+mEHGlvjDmh4x2EP24gKZGceItDHHp6whR4r UhfHoEY1JMALGTCgE41QJJjsUgg6gEgXdrDDB9KQ90zQghbG+AEzJCAA1VdjUCT6QT7G2xEo1Pkm 4coHfmoiJmLLu+B/QMBwO5ENLJDCHCXoRKUYw6wEdOMNJrAAKqqRjUyAnRtT4MY4DrAFQAACZgrp hBOk8YsP2OEIR6jAYZNwhHek4bDA6EMDcJCFGlTABjH3PWrkgYtup7AGSBiBNXAgGUBgHkLAEjaA FgQADT7gF4Ah9NzgEzLBBoBBHi6hBLohA6qBBwiAB7DgN/ADJxTJxW5CWv+a4ADOyC3SCRlq4AMK ozDs7S+ioRsIIQc6Kt+4ATy4weMAwVJ44jAyLQFagQjmIYbqbiFqyA564Qh+4R02CQ1+oR8G7xdY xBXWoQTMKzEQQ+buLxzmyE0qYP5qYOakgQ2kAcv6YRoeIBOQoBFCQB0soByuIAesQRYWQBxg5xIA wACawAK2QLbQ6CO8gBigQQhwAAeGIRhOQRHOCAHkjQRCwS3mrZ4SAOGOgReC4QUm0V9S4Bq+JtNu YEVmYBy6Jt/wAAxgoRVsgO4uiSHQwBL6oRf8Dg3QYP4GrwbsYBN+gRVCwRhSABb8YBt2LL7CJA9G wALwgQAgAQd0ARgHb8b/0CAT+oEVNkAa+kEVJoAe7uEdMgEI6usdEAACQGEdpGcIUGAV0OETciAc viEUNsAEOiEZ4AAEXGAERgASJGBAkkUUEuQ6HnEv9MIF+4X7GqAbsoEBnkAVv4NS6E777G14bnC4 jmHI9EAUPKEP+ekdls3vzq8GaqARasAVOhIJgAEYtmEZnIAE/qA7fM8vwiQUwkEfrGADICAGVEAX XGHGKgANjsAOGEEOpMEOXCEA1MARVAoJrCAE0sAVgGEJMKEEaKEB/UANYW4L9gUrrgKaoIDF4oGS 9CwrEiRF0qATfO8RWQPmvOMPkAAIXOEGoyEYrEB4bvAG+eUPFmAKWlDF/2yAGOLJGcAAGyRiIdyh FRnhJsGQIzly/SogCzLhF1ygCVZBD8KQNeqCI1SBHuLhYJCB1/ShHGogFKxAHezAD4jhDGCHGQ5B BSKgAvrBCc5AEWJhFS6BE2oECZABPICBGx4xBBMAGHLgCiYAaJ6gDUwABSiBPWKNIVIkC1gjRbpj xwrjO2LuKZBhGXBhCPZjG4jHO3hlAbKjBSklX1LyAfolkyqAEdCAEVgBPQ1z8G6yAmroCFxhBN4B DuAgEGwBGgxgFJYAAqChD+YhPxVgHhQvE9CA1c5ActThAkhAFcjBGGKAGsLgGkKhBhgQFFZBBgyg HHJABGYgEgZAJ3YsntfoLYX+QOvk4Bsq6BtwLw0sQBdgrgW3wQSA53coJRQ6IQXIYMdIIBFQYQAI 4zsybXi+I2xgLt8SAA+wARScoTAyiQLQ80lZIUpZoQayQP5gkREYoRM0oQZkkfyuTFQQQP5qAGG+ EBh+4TA34QE+IFSu7OIewBrM6whUwRhG4RDE4AwUIA32gBCuZBIVklKsSjlc9IRqIh6i4REYYhxw 5UQKwxHl7VHHsgXlTfG24Q+mgAqeihl7rAYSchsC4RYIw/eawBy04Q8aIQvEIlVVdVVZtVVdtSEC AgA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209007.gif R0lGODdhxADIAOcAAAAAAP/x9/f0+f/27f/z4+7s8N+duv//+v/9+su70f/7+v39+P/5+v/1+v31 +P/68P/08IkzVf/y8ODB1f/35v/15vbe0BoYI////f/9/f/7/f37+//68/z1+v/28/P0++/09/71 6Pfr9fzo8Pvi71YDM/Pj8f39/v37/v/89v/69syct//49rJUgPzw8/zq3//++f/8+f/6+fj5/P/2 +f349//97/3j1paNs7CdvPPv93mDk//+/P/t2//8/OC2wP/98vv6+PHe6/T3+//38vD79/XRuqtm lv/t8vju9f305vzu5f/+///8/6k/c//99f/79f/59a+CtP719PPi3Pjy+P/46+rx9PTr6vjs5P// +Pv8/v/9+Pn8/P/7+P/5+OHAs/j2+/G2rxEIFVoXXfPv7P//+//9+//7+//5+//3+//+8fj39JMd YOjd4f/s8a+Svf///v/9/v79/f/7/v39/P77/fje6vz3+/bn3v/49P708+fLzEA2U//x6v/v6v3r 6PPn8v/+9/7+9v/89//69/769vP19f/z7f/++v/8+v/6+v/4+vf7/Mx+pOfl6fz29/zy9//v8P/+ /f/8/f/6/f76/P//8//986CvxP/589+rtt3d4v7+//3+/v38/vr++//99olcnf/79vn6+sdqjv/3 9v/+7PXZ6f339P/z9v/v9uKcm93OxMbM1dOMoP//+f/9+f/7+f/3+f/1+f/z+f/47yEAEv727vPF v7i0x8rD0v///P7/+//9/P/7/P/q2//5/HYTVcx+iP/////9/+fU1//7//r/+vz5/P/89f/69fj3 +Pzu8v/w4f/++P/8+P/6+P/4+P/2+P729383kv/x7vjy8fXZzf/++//8+//6+/72+v/78f30+f/+ 5//z8f3z78mvxvPR4v/s5//+/urr8P/8/tLa3//6/v//9Pv8+v3n2/z4+//79Nnw6f3r8lldcvvl 8N3P4///9//99/v6/f/798Da5P/59/379QIAAgAAAAAAAAAAAAAAACwAAAAAxADIAEAI/wCJCSRW Ts7AOEyKNWEykNgWGhmIxakFT1YiNTO2NBRYLFicjceSodhIciClYiVTqlzJkiQTPBoEfhCxqoHB kkwY/ZLYMA4aNIlg8eIp0JcMSi1JluvZMs7HgZN8xekDoCqAPqSW9sRQqVYYZswKiVVgiRENHgPP nVCUzWkXAdQSrQqUCgI4cET0hJMUSyDDpCuZaAW8C4AugY/GxJOIAQMxBrWCyVolCRERIlGifTE1 RYbTYIwYLdLMwsMdPth6qFYN7AY2Kt0+OgXMMk65SWe0IXBMtCEGHo15HVBhapUOECCKgMIQR065 hIMbXdGho4opFwWqVwlUwJy54yCuzP+bkEDcjx+tWnF68pS2ezrbVsYxY0aVPHk6TvBu6WlGFRGQ mLGfQDOEoYYMvmDQCD44VOOgKK1YocwBjjHnHmBMZDDbRsZwos8BTjHBUAaTyCFHBidSQgclS5VD CYmy+VUJUraRpFATxwi0kBxxgMLJPH9gosWAJbV3oV9GEsMLkUnSxkSTJDl1GwZo1OJNEfjAMc4I qqhwgBlHtoSBDiYAws4LzvhiSiGx8HCbLxowIUcx5fjgAyVnIJABE03cVk4xxbQ3WxPBTPKcQOWU c04TRjJxzjkoKRRGMAM2UmAHjNBIZG1P0aEGNx2gcRAxFsrnJG28+JJgHJME0wBwKWH/IAcKaszC iBoMZMBcHBgwIMIdb3igwiImJoiCDkm4sAc4qiRyTwqyMDJLDIqkoQgPPGTgyyQI3RaRRJOUmKhE CA30F0FaMXQuMTcRU8y5yeChSGNQirhuQ42YEwg0vEDZ0BmqqLKmL2fQG+aRsz3FaxyMNMBIDKVe GMcMgUSCgBmT0KGBGg008AsPMmyBTybzWEPEF15s004MZ/CgzQzJIGAoQQkJ1qi9xDiKkl+TaNBe QhvdpsE5AoUnixn+ssTQEAUw4q8ncKwAyAP1cPHFIvs1kY4GQyWd0lOTaJiUcwLhYcIeB4SZ5Afw 5LMkBrzwApwvGWggxyO6uIEIJrFo/2NPMNqEbSITwaQTbkE8TOIYnbdNwoMPdtjG65/qirgRoAJ5 cg4PIJhTgyBoMZSNIu79NYMO7fR7r0SBwCHFOFaEkogCNNCSIG9yBLOND41tVGFjYl9oeTG+WCKC KjDw2jtPCgvEa0+y/aaDC1OowgACisQRgwrgIPGGJOC4kYMxIXAQi6oZnDHJCVv84kM5cfBygqXJ yEEvBmb4kowPkxAT7kCHstxHEoISdZWjE0N4xzzu8IBuEAIKXEgEApYEP4nIgQldmAOiGBIHX4Sn YBvZwzgMsIISOsIJLcgFAWwBA8c45Te/qEQGlvTCcuhuEWjIhg59oI2PLA8ws9HKFf/gIAopGOAH m/gBapxhBQ58aSi3UR4GnmEKVJCgGymAGK/gAIdWWOAFaPLDHwAxjnngQBwUeAAhvHAGX2DrguXg wSd4RBAe+IIhPHBf2OxQkEmgYCQYYIKhlvIUJryIVUvxhD18QAxXnPEHFrjBDdjhDAJkAQIw4MWe nrQIF5jADW5ARwKoYAtBpE0g5rhACapxhCM44ghOEEY1pCCMFmCDAFaoRyJaxgOn8AoNDBhKv4zU v4YEYydA9MtC4vAOHEghaucxDxz4YIUUsKUB5ZnAD3KRCyN4EwybsAAFnkEMSmyNTuY8wwbskQw6 yMEXnOCiKETxA1wqA2myItoWhqD/AGzx4AwRQYhzumCPczjOE134xFMUcsGcPYcJnfDECezFkC6E xxyPeEQVvvAFS7BvCD8yBjb4AIaSGkEcrajAEwaSKh8k7kCKkJZossGLd4iCDGQQhhPA0AMrdIML hEhEv3iQhlrk4xkHyIYLnyQQ5lRCG79hRDB0FbGSMIlViqjCtLigCF/YiQfvyEQ1yDCGW5TgCD0g wAA0IQkIRMEUDNhWQeyhgBgQom8CqEI+zLCKBCTAGHnIAiJMcYhHCOEPRIBEZwTAhlQQ4hlBaEc7 1HCt5mTrUXZAQRgEQAM0TCIbqurfnZ7Eg4QkDqInOMEMusCFWNTjDDpMnCLOgKVM/2RCCbZwx36M cQNnIIIQ2YABGpIQiGuU4Q9/eMR4bmCMaogCDuIwBhiXoAQ3iGMcBHiAB0gAiApYwRYeMIUeqBEw QgxzVy/kgatqUQup3ioYaFCENrYRDB/oEAHYW8UI5IFca4TjGuGwRjPKgAVAGEMKP0jrA5ZADiwc IhHZ0MajKMGLSSAAGaltTNj4VIwufAAEQ2jEOiaIAXaaKAwf+MAQDjGFKKggHzVgAQOYoYD8aSBB 2LLHDPJ0hhnY4wQlEkwx5BAuHoDiAzq4AgiuARY26GMZy1CBITbgAEjUQAWHcEUCcDEQPiTgERxI AQJaFq5sHIAHZkAAthS2IeaUqv8cv5AvGnywjVlEIhCouAMgxgiIO/zBCgMA9AAGYAtlCAIa0mAB IfLBL7gtiQeKqIUJArEBZ5kiYKpY1hgl8Qc/+IEcgAA1FfxajwPgYB8AQPUYdGGGUUAjgs8QRCxi MIoUZCMWXIABDOpRD1xzARrP4AJSD4DUM5iBB7c+QCKEmo1JCMcMMEjEl8yQCEVAOxbPMEM2dKnD CEbQDMI5AC+oDWFpU/sAMHgGNGIQi1dr4ZQCiRsxdnCVeFBl1cTQ4bgTQZ/g0CsOLXzhwhqzq/4R nBjgHrh9n0eq6A2E4HDL3yxooYBEfIEa/aShtnmhDVlAwxTyQEUgaiDsFECBF67/2MEOcHANXkQB GimARihC8YRoqGAUz6jHPWAADUKkQAtaSEGuEwENWCAABoTgNVK5gABsa0HXWoBFtGMhHKnXQxCz NcMBlC1UcMMCFtCAQV0PIAhBBAESpkiBILQQg1nUghqmgLspTKECZcCgIdLmxSPQwXd0lIEY6qMh BpQav+hZiM2+bGrzCO5LQbVsQ6QaCA8U8Av4CUo2Q1GSC0l1+Pi1JQNoKIQ7UvAEd3iBCzPPda4R UDVoKEMZ9SAEDGIBi1AoYxCEKHs9OCCLGOR69jE4urHNEAsEBPcA2BbEXbXwDBh8XRYOMMU9CLFu BEDjHl4oRK2VYfsHytwdysAE/wc4oI9uiH8Z3XiCIfQgjYbEzfPGX1LcGgPuft0POC/sF/P2n3jn MYUkd9IUsQJ5zPM8iccF9+B7v/ZqUKB9UEAIhHAAXFAPyuBqXvBq6gYNsTB12FYPMQANYxZcMJBm uiZsCLBsMBBc0JAI0TaC0cYF7UAL99BrUpcIxRcDujZzXkAIMpAPUKAMKXAPURAFD3gPyrAMhaAC hXAP0NAQu/Fs+AMmvxE/cSMgy9Mkm8IbBJgWDQAPJJBnJAAPtaAGwaAGlpdM/+c8/ecXKvBrXJAC VdNu9TB7glA1XBAD91B86iZsPTeHMNBaLIMA7wZhSaUIiiBUXOAFaRAJQoAOnP+wGs5ADn+ACFZQ BtSxMtIGC601fSoQhPmwhBxwc+CnDNTnBR9YgdAgC14QDabYEPSBTzwgVIMHbhYif+93VYrHKnLw KIX3EefQAMYwDBEQASVQjMU4jMPACmCQBbBSGweTZh6IaxAIDTtod4SQh1zwJbN2dLgWC2cQC7Jw gqNDAyNABT3gGtyUC+eRAxNwB/MgDnDwA95kBLkgBvZoj61wBcO2gemWCGiQDypwD7KQdKGwbnYF DWjwhkwHDUkYDTJQCDLgBdqAd9nwT8hWbW8TN/1STCTBCzKgCBspA+DwAxGAalZxkiiZkiqpkmPQ BxPgBxCgArvhHCRyhVjIGwr/MGvspms8yXrPIEFN13yCAAvBFQ3MIAD6oAdzsQocAARlgAOtdASl MAyl0ALJyApYyQr36E33OAxt0AZXCQZGYAHGQAUvAAx54AZZMIlTMAtTwAIsQA2GEHeQAAkecJfU wAyHcAjMUARFoA8NwQNJhWyOpjzjBjeH5zwYYHFBgAAxsArjMQ5voAJNWQa6sAPxcAEruZmbeQHo 8ABwCBy95H+kyRK6RohaJ0HZoHUjqHVb94pABwuCAAMHoAWxYAawcHWxJmwc0A1UEA/VUJVOMJxO 8JXDAAasYASvsALYYATYgA0WoBrOMJ1itAf08CV2pA3fmGY2CAu7xG4QNm6z/5cNd5h5RfFCu0Iq 76eYMaKG0BMlzKF16oAOVMGZ9mkVnnmdKtBCB8MDMIBf/Eh1NqgF9GFu2oZm1DaUIxgUTzRutakC JCAEBaAPgoAJ6qAONlAE74AP+PAO3/ANzjABUhCVLVAKpeAEEfAKrYANboAL6hB1XyduWhc3XyIU 1JZJcWOgYOI7EnGCu/KKB7cRSdIkTsELkDkPyKB/vXEQ/5Z/4HYA9eABUfBu81eatPEUGvmK9DFt BwALr7iarzltXjptZgAN8jAP5oAJ9PB1YzpuWqdtq+maW1d1MAoL9AADpwcLcyoc+NOg4Kaleqql T4o0S+KKwPElicAcS0KLTP+SDQNBIVGiCiRgAmywowdzqagio8Lhpg7qpRGnkaDKK3pKbND2JVu3 p0tCU4tKha8of8ExbrDKK1Uop1XopmYWqNNWdbRIiw3xDF+naxuYDS3jZi9kBhtgpaXpNZi6rCrB K28qf4KqkfeDP1k6f1I0fwJSpQIiEW9Df/Pxp/Qxf6AqruGKAXrqpc/WpeIZrqiqpAKRAsVnfV4Q C4oAA9Tyh4SAX4nwT200eaPJcKPCrAJ7KrqAajvgFyrRBYwQDdCwAJtiLr7QDg4gFUJaMAJHDBqg AU2wrFuYFIVxGPNmGCkxC0iAF8/wsAKhBjQwDaqwCkhwD3ATBXcwDndADuT/8AKSyEID2xvKKhBy QAntwAx2hBR1sAHjlg3SoAod0AWK4ioNwA2zoAfgB6+0BwNnEAfnQAn0CqVQAA3gYJYEEAID4AfT WUl60LMXUkFhggEI0LKr0A6V9xzHQBEj8AZ7hgiI4AeIYA3W8FarsAd7YA1mQg4T4AiOMAxU2QIl +grGYANI8xSbt6zlkA6UchBG4hovYA2Q0AiN4AnKlCF9ggGGwjhqOxDFkA7f4hfnAjSEQ4bIcAX4 oAtUAAQJt7Mk4QmBUhJEAAWIial0EBgRgQE+EAw0wAB4gDcTQA620A3KAA1VtbN10jXUqgWhcGba 4Asqcg6KorHFkAEzhAEP/3UONGkuf0EJNzFADfEX59IEntAJAjEEV1AEyFILCpCetjsEkcAAUYK2 LHG+JPG8xJABSkUMPlALs9AWxOAJQxAIq9Be5WC/K4EAbDBMxJCoCCADtKBfWZAFS/AHimBlX8AC ELYNlEAJTSC+xYABj3IM4ssigDIuOXM5StJQNUO+OXMj7/IkW4AHCeISAdW+J4AHHUCGYhMH6xAI FbEtnuC5ArEFXQAK7REDLBADwOGutsspzsME9qAGi3C1JBEuihOw5OIJVyAEb8ABvHoQvnAO6aAG j4AIR1gPstABi6BD69ABv+ALzTYJB7DGDIUUT1Ij7NI/xcDCo3kOulJI7v9SOe5JDJpVA4QgIOWC sIBxBcwgyZ2wBfRzLhxgC6PACKbgvCr8ux2LMJFbJDAcB8WgBiIAD6ZgnmHyAfJADbEwIONSDhrA AzOgC7sQAkTgBQggC4vwC81RDopUCVFxOOpCNgmTMz/bL5CiturLyOwyA3TwT50jA2lMybTRCB9Q uSVBCroAB1OTAomAwbKgf3FQCZUwGAM7pHHwC5SAATIgBPCQPUkxpIyxFDNwNrrEC5XQAeV0Dhnr C4qQAJnwCJgAqeWgY9frbAWxBekgB9liG1GxEOHiC4WSOJvkF3QiIhckIkNWDJQwCXPUCDpAyxUJ HKL7Lg8sIksxMxvBQUP/UAUK0A4zwMTkwgMIQA/zIAoGUAEPoAVd473w42Ya3QBpgH8QTAxEQxsY EFAAFAxCIA6oYAuaEAvLxm8ViV6Qew+KgABP0hjbYAImkK/OhgFSIAVeBAzO4AfWIAGBgAM4kAcP AA1n4D53kgEsciJTWEGJcgJ1gAK/gAYowi0VQgm+UEGWY8MF8SQmMgnmsAu6QNc50AplCQi2AAuT bC7Okw3c8QRC1R4FYIzCcJxGAAYRcAsRIE4/RUPjQjjb0Dsbgkiy4Vnf+7zPMXhapBSTAAq6MFbC 0Aal8AqbYAStsAnsUE28kCi8cA9vIKJHIApHwAdCLQjgRiqNoKEc+g4g/0AKQSAASWBGosAHFNAN ofAMMUA3BjEfn/AxMex/TOAJW3AMt3EC3isVcpIoCAHSDPEu/vMcG3sF6PAIWIBciKAES6A3KeAD iKwD81AGWZAHL0DhaFLhfyAILJUNyLDdfqkPmKB+P+1cCNYDFVBoEuQmipMBtMAI8/e8hMM7vqgh 3FIk6YsoxAAK5jAP81AecDABSgABy4BfXaALaw1LX9kGw3gEt/QAJHIik1DIGjAJf+Eiu3gO5jDO rhOP7HAKgiA3ZoAGlKAIQwACs3APagZQiUInJsI+nyBH9lDSGVAOFPsnh+K+ghQHnUDnnVAM57AF M5DHGfAJW7AFKHACYf9FRGPVB65gBUSATEpCjQrwVbywDQwgA8ugBx7AAsrABq4wVmQwjKLwCqlB AX8wAn9gMpIACNZwl1NQCDT1EZNAuc8BaW2XBCygpwYjpEw6CYFDBw3AAlqdDTFQ7DGAhFlG13wQ tpoAAwy2BHlQBtGwDemQDKRQCCngDgiYAuuwAF0wA1dwBQA2AB4AdyygB3tQBeuwCHiAHJBQCNHA ArMgA9GQhDUQDUpaEOJ7G3XQBV2wAZ4ACpwbBgQfBnjADQqgxzyABpt1CGwwBUFACswQBEHADHUJ Fj+ivPUwEJLEB8aA4pDA4wduDZLQDNcQCdzABQLA40IQapL4BiMgBCb/sCb5MA2QgAWoPom2QASI IAF3AQ7LEHC8wi1pkAZjxgPuaiGL6QtcsB0mMA6oAAgd3Gl6iwsQAAEkbw1K4ApFZAFC9WiNkTii 60u0OHCdV4vD1HhMan+ykTAvVCQAu6TNE3lqCLkRsykL40PEqjz7NyAx0n8PC3myTjSlYoD7qyHK 2vaKZ7/x0wcXUAZACAtuoAtlkAKvVw/PYHdwaPm5GUGxgGvo+gyEoAyfL1Rn4IJzGAuy12+88IcX w6CyEAvI9/WwipvZkAi/tkaFkGuw8Azwum3XiIFqN2tcYKkINxQ7MAZY0DuOP8EPTIuqKqs2ybNr T6w8YX8YAEJEISjQ/8O2jEANLCADwacAMkAN1LAK8AAPqzALMID0bB8HdagM2r6AKgAFoZACocBr ofCAd7WQhlY1AKEl0TMt90bBSCToCYxYiRLBeMblmaBQDWHBYAjrwAFeMMxki+ZFY6IDXGCZwWjG zIFniQjVq8eCWioO3R5wGLVs1Chlz2AIgqKH2FBivMzwQmoGQxwMRpMixbCUR1ReQ5fGGYoVK1Gu cbZm5UoMwwFGaryGRbtVq1e2Z4liQNs0BhRl95YRSkFIVgxooepBi0UomgoVKUbhjfEM5ZN6LRXF ggGrHgIuXLTA4hJrpaBECBIFuZdoJUKEKmPdiwERhmcEfAmpKDQKWv+Ke3hHFYKSe9Q9aDEIhVKm IhqHGFwh8yqXLUM2GEiNHoXK1OvSqEu5wpWOVntaYtIYwd3eNav1rNLZEvPKi0dVLvVSQKsMkwsh LqGe1YMxan6KzPDvC6KPEEIEeUYyLyR65gCVoIEhm2daSyQGL2RRI4BVRBChig7UkIGLL/KpZyOE EoGmkHsMWya3e6Ih5J5CWoxiFC+eWEYWAQshDBquVIKOl6Z40SYb6pSazjz0tCsyLR7SgQcbMMRg ZRhWWAEjFwuAAeaOJH4Jr8u0sIrqSLEQgA8GLlIIJcJ73KOIvkS4kMUXhhLJhhfmMHoMogO0oSQY NYIBVJG9YmAkCWP/WjHCiFwSZRQbdnrIwxxSornHi0K8gCKaQgqRBRreZOMLChW88O2wEz31IhpF ouFixx+ZOgq6H8FDEj235FBlBGwMaCGCEn4lI4JhNnEkAgCO3ecWZfc5Nh437hhnggkMcMSAcUzh YqqwvvoSg3z2eGOEEVxIpcRlGIrlvntUiOUMRQaKEL7MBkpXi2xi8SIWLvIZhw8xHDmiDScccaSF FqQUw8obLMBmghyqEUUcI7ARA4xWWjGGCjceweKRR0ZQhp7OZLinUhdVIMQLaAxJgY0iECC1xZBi 4SoDpHhQ5AyjpnIu1iKlww4DNBDwkYtUcBjjWKWXZrppp5veZ4ci/7qBYRLsePGlHLWQpFUliFpC 6T6fEolFi8sgwjebhw6ARQtlRsEEEw7YuOaacMpAx5WHd9AFDFZKcULKKVdw5BUxxBimjTYOfsWR H27ooYcX5nlkDXpgKZDsGBSQkAtFWOICGmiggCblWChrlSgfr+LlLPKYQgostaSLPSlYYCGEDXnu mKCPp38HfgxdVHjmKlu9JGorXi7K5gAMUOLCTEI24igRoxTsGRZeBtICJh6yMSOzti85BQcyzr+A jBZKKYWVXKAspQUnhBGmBUfEMGATyG+4AQtwoNDIAdTGtqOAD3siut0zdBaHA3CLLdaBCwSRkp2w HAV5sFsFKkywgP+NmOF2WlDJAQTRDQq4Ih4XeFofXHGKJ5jBLcjbjlJ4cYBEPA98JLkd2+gUQoGo zSTZaN5G6EEPF8yDE4dQx+VyCAuHRAYj83mGOqRoAytk4VDGMEYelGAFddwuhFHZiI+ecz0PBnCG sDAgrYihPTudoTpNUUpXuCUe9NAKA7OYwDwWAEM+bmeOfRwK20BIxg6uxHkcicNzVgIdWIQCEocI ghJhERUeKXIlGjnKWDjiQTPwAJOLNAolYaAgOF5ykycxgxawl0mVsMEMXAlg8zQSShmGSSx/1I4s TDGL7wDSl7/cTutI2TOkKEglxVyKUbxiBlkowEdKed7zDKk9aWb/8kex4hFHqKJIAoIyKYYMYRid wsoG9owrGOkMAqLAAtERAgH6ygwC6mQG663OgcTQQAaAuU9+vqUqoWxddaBJHefMKppvJNJ0fMQU Sl6tlBuhSibF+MyVjLGS1NukUiQaTuc1hSu+mU3JQqcCDhgEX4qIgSJ8oQ15TqIcyetnTGVKjAxo owlyKMYjOBEHJvQ0Di/tKROIsQV7nAMDyCjCB8KwhfD06Y9NOAcxhAoWYpSjHOdIx0wB6Yo+XMCr fcgBkoLBCBgQwhRfeOV2MkCDVagCAcaLQyKmAA4iKKMeFIlFIRahNTXWKjxM0KcfteMLfT7iAvGI xz52QVOsTHWq/8SohAAgoYJEvDAsKDhBL+qAB2rwgCi1gEcSprCHtsoiEb7A5S9T26VdMK0PBdAO A1YxgjcMQA/ToIYpFCAkomggGF8oGQMiMQJr/GEcVHAGlpyx3HHcoRuwsOxqvaS11gl2azsAQFiJ oQsA7KArvPiCN2bQiTgwAg8sYEFwoDEQQkgDLpRAgyLe6gNtbAASI/jDAKxgC/4OIASIuIZnZVqO RQyFCX0NjyvGsOAxXGAHQRgTIxpACab4IgABQII1EEEEKHCgECwwBTupQQtTeEAPerBFCFCxAjAY wQIWMMLhwMCHJdDDo1q1FVMmURU/TkIO5Zhq8xKRj1UkQQeNOP/BT4vRiWLY4wMfcIE1iLAMDxCB A1AwRSIm8QtZ3IMDA0AEBABBBQvcgB03wMaL2SEBHuOYK1qTqpeYcgBarMIEJhAAecKyhQ8EQggk GAEgoIUKeARABKhAxTwo9wh04EAU1agG/dpQjRxQoBsd1YqbNaCBofiogkkM3Wx1cIUhfKUYlMiA 1qz6WKKcIAxD6EJft9CIIaCgCU0gRiPekQkciGMCCciCjRfKaq2Cgg6T2I4H4GGCKtRBul2qRGC1 gwEfLMUHjHAAM3ZdjRVUoBvPWGg/ixGeDGgAwdjABhY04UKryuEccvDFJCZRDCbIIQOp1ppWgDqU c1S7scQoRsD/AZ4MShDjBFsIhgaKkYwrzEMe7oDOs/tJ7EA2UKYUDwu8fUGMSSSiHNrAjDngYABA WIEDzyCEnnEshwDsgQNEkIAkDmED7VHiHL8o9zE4Lgc6UEIbxSgHTnsKZJoKlQlYkYMcECxUH8hh qvYuRzE0oIYuvMMVqNgDNGwpcV/GQRWm2BaOXyomOqolA5WgBPi0AYIhBKEKIpDHKmTQ5vDMLnlb E8sZHNAMVEzAGOPAACEUoQg++SAD8z4wMc5B76BnIGtMiPo5vOJYqf7CssT48fG44tgwhIEojdCB CFaxiDhy3UtMoAQkIiFHHL/7j+XwweziYO/pUKIWvYSpHNLR/4Ba0CIGV3EgDyihA1NUEvbB0IGf 7yCJP/xBAsFQxR7QmogMnKPjUylHBppg1ZdSYhI8AHKqAT7uWyp+EkwJCxM6IVXys58oW8BDBlIL /w40QAZRwTvqGeFZtzTByUo1BUUgCjQQkj8yvZj6MTjDADVQBUVQOTFJpOroEzVogAqshSSYByGI gpN4oS0Ig0iIBFWYghhQAWmQgW1gAAVQhF+QAx7IAKFaDgyYBMjjqZeyqu04MGQbCpzCQVZjgiYI AzXQwTjrqTgzwqHwhFkLAzxIB3MoAC2gu/djKqJgAFPYC21YqAOMqd8jD+oIhgbwgjhSrS4wgRFQ BQXgAfQTi//qMoNYUIZsYIFZmIVokAFtAJSaOrxyoASbe6mkc6zHkgOpYoLFMzCgQzby27egMjAm 8AU8CAOUij2yk8TwuAId4IY0kL/yCAsE0AMP0K31oAQ5uDxfYjUtRA9uWIU9iEJAioMPMIEssyPd 85NMSABACAEPEJAaYARtSDV7QAFtOAMXnIQMSLqqCsSqUsSgkgNOMzBeOLw4oDepQryeSgdRnL1K GAId2ANBqC46CotimKMhMAcaUDlP4Io7IAcrwIR6+IJFiKA++QUEUy157IrzwwB9igMBCARVyIaY mgETWIWUuzxfGIJd2IVwWAhF2ABKEEZtqIMZWAQE8AEbXET/geupYvBDPzQwHxjCxyoHHihCObCH o9MGHdCBxxAwjHu2IbgCGujGsGgEXYADQLCFFGiJGOCtoUgHNDBFefslSsgqYlAAEwiAtPLGo4yL KghIF8KaBiAGNNAAHgCBTNgFROgGpLCHZNAZH2OCT1ADH+ABl4q6jwSyPhSqchhGURREA+MpoQLH PfuEofiAAiiEyto87ShCPxoCAciGUWxFOICDOwgBDkiERWCE81OLc9CAM1iLLlFLpKQqrjgDM9CG O/OCB/Sj1JqEDQDIZYAGWfAGEYgDbTiHnpsETtAFTrAFLUCIc7CHNEAAbQA/YvgEgtuKH/PDewOy TwDLrbAq/wG7y2Ostzj4BEqoAxDAA82gu7Y8kqCiR6G6AgFooEkouLDgBXOQAjjIgm5QpViwQ8mj lXP4Sm1xs+TZvjAgASQohGywRxdqixzDpahAAxEwgazzEUooh5XygXjjBR3QhV3wgxaSwRsshmD4 hXJYii2YgXbYBgQ4g2wAP6HCgDNIhqxxOqkiuqBaNfZzuiJsAuSbhzfggOhRD7Tksa1gghkkirwc txnQgSCwLB6wi26wgiWQgmr4AQJ4AI8QC8yrhGCIxKZAA0a4QzVMJCy8oPI4j/cTOQN4gQoIgQew hW5IASggBI3qJB5AA8a0laY4tCngAuthClggByrIAiUIgf9wsAZrSIAcyAMrIIREMDwXlL9zsAMf 2DTHG8Y9DAZe8gU0WIe9+qmxE8S3PMsi1NCok4NPuAJdEIcbcIYKsAJLowdBQACjxEtiEABzCILp JIomOAJRYDEwINUWKIEIMAIKAALFAD6pygDrMA8MkIM93MOpsJoISpJ6ZMz8OzpOeLRqcAInKAVS FYcctQVlgIEzOLzvO4AosAUhgINxoABbCAX1wAAcyIFWgJwlIAc/QAREcAMc0AVLaxdt8AVKoAPr 44EZQIEMqKFJuCn0OLUd84F09YFtQLUM2E9iTNGhOD8D0xo5gFcUkAFmcDQp2IRWwAZIJYAs8AMQ wgA4E6r/SUAAU4CHBKACG0DWRCAKwxKGNogAJ6CSv6GfYegBS0MI9gQ+bdiGYMhENfopsdCGSfAB BMiZrojYt1A5JtAAOTiDRn20IygFRxhai7GAEICCqsmGAJiHBOCDVvgBI2gFMPgBYKCAEeW1HEiA cciDJbgDeWiGZoCHeRAFOHgBK+iJbCAs8UPLExDFqCg4pwMyOpjI1kGBGQDLSTgDp3tB7KBBQeyE JIzLK8gEXTCGNGMHjWEHZ7CFZ0jDcvOGa1gCJcgCKniBJcgCdvCDB1CAodgCXhOFsnU0cU0AcZCC 89mESF2G0IkBNzq/LasEMXo9CEKPfMM/mCqKvmICz3oH/0edByrAImPggyx4AC4AoiuAA1/7gU2Y kuZtgR9QVVcthknwBQ2QsG34Bd8Kg3mAgx0QBWNVBi7ASfx0S3uo2arIPIAbChQ4UI6zB3uAOsbq qU5AVPa7t54SR3O4Bgj4A0DAAkB4AGjIhhMgBqvDAmd4gTwoszOzgFbIA0HgCl9ADh5Igw6ghWmg AWqYhUbAh189AjDoAW8LhaPgP0rAg1q4zMgkinOIqjpCAwWA1WfDv6XwhEYogisIhCmAgns4A/oq AnyoBjK4gFtIllMFYR2VKtwshnP4hHPoBK2BvGMoBpFzNDKIByqwApGZzawYgg6QLwQAKlRjAqAr B1urqv/itJoVlQP6hTyOOwFEHeMmoDceEIAqUAQeOIFP2AIU4GAcwAE4WIEjEOQccAZE6FyiAL9y 2FIfIDwEiDf2RIArwIEg/lgnOGJ1LCsvUAEPaAYk8IDm6KRLfbNjUFdtWAQVvF3c3ZYU7T41oAEZ IKzvOwNfQIAieIdJhhhx6AFbIAIVKApeGDxKoLc+6ZPdWgSdIQZfmIf/DF43QAWa9IBIgIR28IIa SII9KARGoAFF2J7q+ikmQwE74IF1aIczaIgzOAO0jFBPsJpzjcZBpAR7mIE6QAAeYOL33QI7+GFd 8OMdeIQHiIIhlJtloIa65AUEUIVmGAES6LsJAIQKoID/XYi0FghVUaDKCRiHHliCP7AGScCCP9gw DyCtPTCFMGyd6aC2beAG3qOBTvEIpiSSpYhBIFIJRoi+TlQFVViFN4AHcfkDLICDH3AGS1OBJcAC IfgDd0gESmCCX9iAIAgCL1CEehiFGoAE+uSER1iCEIAAD0gFFTAFNjCHQPAALpgFHbgGTbiHvSiE aFgAUmCAGJjBctCAc/AFX6iDLhgCEBCADmAEFvyFYNiGDfipfmPM+c0ABWiHC2aBDuiAKoDsx6YF GbC6P3iAZWizBuYDQCACQoCGaQgELAgHNbUGLDBtj8kEOMiYFyAHckAECfhpIWgGFlCFJPhfb8UF kfbE/+hL2jM4v7DUFgzgAV7EP3krN0ZwbG+oheUOAFVwgRHIgiwABG+FAHBoBhP46D8oA1cQhSPg A3awAm8VAh1olzOwB7YLgnWw6iDYAF9YvHP4ABBghimIvj2IhCrQAQHgJT/ZgCFgBnfwsEJQhBoI AkMIAhnw7ag7ASCbhKxEgJb1BR6oA1/oSxlMwiHYyyqIBBeAhGs4hENgg1QIAmYAAfkOgiiogUNA B4xFBKLoAQuYADfggDg1A0UAAXMIPR2ogg2ooaIghi4AARPIwEDQAWYIAmhwZZZqgEgQASG4A0D4 Az9oPkSwBkCAAGVwCFIxg9aILx6o8e+QDsgrh0TQUv9Di4QamIJmeIMqh3KQhgAqZz5yyIJdgANs KM87x/Mu+QBT7KdOuLXjATIfqFkZIBquY4Kg7BKvsBrE9DHMw4PfuNK3KJlQIIR0oRO2eSczYYnJ ZI5EOAMaGiVDGiAaWo86IaYD8IjniRAXaor1QIoGAR8IXR2OWB04SgoYuIdsOIMGwQiOwFmmMPJ1 YAMwKSbwoY7qWAu3OAuGmg7N69KTRj/wOA87ooo0aID9Y/WlgFBfCAY0yIBfoIE0cKOo8AFVgIdz j4PEWixYIIYd6AN0OABoEATPaQ9PiQj6gAH7ECGYeAiG0PdRmqcd6qA3GZFjYiJFwAjmUBvmgI5j +gj/0QCfZ2gJh2AOzaChhoABmMDUjWj3McAC9JCFrrqGpGgKZIeLqpjhLHwLsbiaE4X2OPhXVV55 ttgxM5ABVaAGWQCiWof2bPiCaYgFmqahONCFBsMBV8CuPmADoKiH36AIKOCJejiQzEgB94jTZ1CG WNCXWIAGxXiIlbAe6kkQWGgItYmMA/Ds6KGh5+AIBekMBhGEe1CFWUgEjWgbfCGEiPCCl7gPyOCK um/3fYiHHUgs4SEGOinAaGIo53gg4HuhZf8K46mjNNwOe3ger1AEGZgKaNpyRmCAiAyoWIHQ0/E0 YqjSUcgNQiAd4EiBvJj3UQiFqv+LUKD9SR+FesAc/wZBgGcIjJdAF95/Ii4IoVjA/VhIDNMQiaMY CFRHgBFpjIeoDEJYgBGPhD2YAp4ADndQhhTQB2ZIBRa4ju9ZDZIw+4Z4HlKKA2tyi5I3QNmTrju6 v8hUdJjKNJbP3bZ4IK0Q7mCIhlgYhbwAiGdc7t0jFAvGvRTKCD0jlIJLvRgwYDx7YkqVimf1oBVK 4THGvViJDsLSIvBMtkQHYMWCRjERTBgHorHgYsaMlkRmDphB4NMLoULT9CxjAcWQHg97JL1xESmJ DhHwAtRQQewqMQwYsmHgxSMbL7BmeJnBEKcrL60IGAVLmzYOXLhY58olFmcu3qsYfN3Ni7XvX8B0 Mf8EtpvVLJdYsbhESzwqhSAYT+pBTARtFEEuhKBxgWYSlqBn0AjBQBAjUT0EsURz0XnAZ6wDB54J ggVLNg9eMLRwYRYEWuybCKCFUlEPRqx69Q5yJrQsBSFC97xAuwclxSjphObqvL2TF9mxZHmdjWv3 7lnCdK+m9WvY/dVJanjAh28+rtly5csT5rUaRgycpQBFdaMpkwJBo03kEWnLPRPKRJ2tthoCZ5iR CEs3HQDgSIlwgYBOZsAg4kReyBADLM/IxlM2ihDCxWuXFUJZQu6oUB0HoXCBHSabQRPDXOB1VRZa 2YiFwSS8ZCUYXoAxWd9VcRTDxF8ZpPEklPWZt6T/VtB4KV09gkwWXT20pTBaNPfUEwp0o4QiCBdx 5lMTC3ok5qFKGyLn0kixsARNPSnEQN2IJhlSwzPPwACLh7LUA4VxykwXg3QKFULQY6MUMgpnHC3j RZDgmZFSIl1hIJ5WkxCmVXrvnacXllHGEcwqqPBhhAUW3HBDD0v8EYkIjGTZZAZ/YaWeV+nFMUlz KSgnCDTPqEDIE26mQN1yochCWyyKXMYBoIKEyWiclu2k3DMqQZMPLSIIMQ8nnDzySB4FFHBIBx18 AU2Kx8FASD2j5LOppipEMwoH7kCxDAdReOHFdAMjnA+Qxw7JQwZaXYhqHKPul5Vhrdb1qsW+NIAK /xjDOBEByyVE0AIrYhhhBBa/DBsYXOqZFbKscWQTQz2b3RNgDDGo1llnBS030jMkmeRlLAiYwWg2 svEySTZfHaSIIsw80kqu2MyMzQ3kkOOHM1mYI4AsccYCcSEqFJLPFzEUskw+BN2jghcBynKPlyqM ArHDiszFw01bgXVAWGbAlZZWrGpFXnlZ8RCHL5NUokYtq8Ajzyq11NJALSKM00IJJdyyuuqr37JD K8yoOkkG5EWpHpQjBzYJA9Motlq6lxU3IyGUIhdDoolF/VIsYcUSgyL3BCDCHXfkgQoqI6wSwCzt TgAGNtjkIgb5MuN6AxVlcHCPArLIgkb7shQCRf90fcsCjSwqXCvLKNHQj8AoBhcggxzuNYrwBXi+ khbHHSYucrlL5MyiFUbc4RURuAUAMqjBDO5jdRv84D728UEN7uMConBBqUgWpav4QhsIyIY2ZCAN BfAgcuSBzUgSA6jWJE0RMDnDAWCSiBf6JAZfiEZpZAAPKrAjFwZ4xStY8QpHOOIVK9AFNqhgDHFs onybeGIOdGGMO5DgDqioHglWEQqWKOCFMECalxQQDS9BAXCGWEfU3LcIRWTjcOAxEg/OcDnwvEV3 7DlLIAXplWiIowQiHCEkIylJDY4BB25gQyy00iTCxEouoZkIcmDRmsXUg1EIKA0MEqEiReUjH57/ 4cKlnkEPLOTAEaVowS1xWYpSDCNmuMqVBWYmhleAQQy4NB+ugMEOdrwgC3eQhzvooQXFDORtfVMM IR6WjTeqgAXUQAI4uTMWxhGyK+lh1e3QwzlTxOIMAaAF48xQj0fE45GTvCckL5CJbzwhFpfLipJu NhfFZGMxpDnANg+wmDhxITSKeQajbgMaQXBAB48QwgggYAVdSMEAm9gEK1jRAie8onzlCyn5WHHL Njihl2LYhAV6AIwXOMMY82CDOrSQk1hE41LRqiN1oCAIerzpOJ2BQZASwYPLnUpIaJHgX8zCn7Mk wgs1YEYBhIA9VJBgDzYAAwbxKdZ94GAUT0BA/3twJ1BiZMMnsrjJoryzTYq8MUI3ycaFCBGKUPhp qFoQRCg4kAoXWOMOVLSlE0YqjGGAAQyscEQL2uCIxjr2CEdYgRRWMAFjYAEItlFUKqMHHNFsCwbH OZoqzbSouYjHLXGwWlO3dJa8OKkvZyHPAVIAhByMQaxjzcQgYOG4WNWHkwhAaEoiYxtYICddK0lN ahmVWi5MhKBDfFE91LFbMrShDWT4LhkuEAFiGkEMw2gBSM2nqx70gB15yAIWPKAFRvHiDMih7gF4 oCJeyAaviYCBWM5gu8BItVXviUNAZ7vWFWIABiRIQCZ2EI8+XOACfYhHJt5hgT7gU59A4IJUF/8c pLaKRBHM5cmFEAoeFn2HBygOIk9mE5uVaIEegpAACQrwjkzEgwzVqMYRvrgJceRgiqVwgjCcsMsW tMAAuZjABNxgC3WgWCY1bKp44kmWU91kJ2qd3G1Hhk7iZikO1BjHPA7Bk51ZToINxskl1nAKdOAg HjvIBDrK0I1QtMdVIibGWGyzQCF2eTxkQXFT+Ts18ZQEFiwwwTzM0Q1B6LQkOn0CJuihaXXE2QrG yMEKVmDLI+AgB+JohRseQA/Z7ISc5OEvf3kSFp6cpctjUSvkJJgzBDOOzSvMyxX8ggF5TGAevSDG AdZqyDgsgj540eSfTyVcFE9NNoJeiW1e3Nr/FclGC0iItF+tTRZVpnJRoJUoLKSp6UvY4AGaeIKm hXsbLceaJy5G8Xh20mq3zGXN5VTW5Mryaz/TNgbjmMAh1PrnMi+YB9q4yoZ2gqHwVHslrZaNEL3z HS2YIgn3ogcswkNIUY1TPNXmb7atPaINWU1U1D40tsk5NeGafNFm6PeWSc4LmJhlPCMz5LEQsArQ DZfMCz86Xm6y4gOgZYE3gYUN10ykscQiHx5497z5O6Kn0/vQZNH40gWh9BirSOYkF48W4llzVjOd cXM5rm0APCoE8HHkCFQStP2Ss2xsIxtGRzrgWctqp0/bal32d66VPva0LxrfOdeYrMsppJGz/11D KdfQi2ku87EgeMUBvUpzFGMaBGhDFge56xnqABZWPTDwrj+6qDTmFle31lSvJs9OOo/gp5Kl85OD nFuUHjnhK3o8rna5vgk57xiH3IatVqtIAIwc1YgktYpKlD9zo+A4JOL13l8wmAHKn7ew59aanO1t lYTgc9plcubs+ZCE73u0cOzQZYH1rZU+ciXBmstMikYM7IiXcIFAHMQbBYpiKIIP+EAG+MyWiNjf fR98uNnngcx75Bp+SFWIPY6vKYte8IIP1FDOsJ6pKMsIrsp4hF9T2dCQBJz7zUUAQsQbLcYzcMqg yAL0eIECqIoERqAE4gUTxIEcTIIPRAmVyP+BHODFCQxBW0yCDpgDJDACKTSCXxSDGkxCXqBAE2QJ E8jBOVDJD+rdOgTBBmxArGQAI5xBgzlALTBAfdCAKiCAYGCADxRCKDxDx4RcHPAAGvCFwg2LkwhU X5RDOVACMZRBhbnCVTBBOWDFlFzFFtjDqSxAI3TBXEwJGGaFDJxBXhQDHWChsRDDJJzDMbyeDxLD LgBAH6wiAOyDItIWI+yBKUSBIBAXDdCANyDBHtiEXZiBHpQRIADCH9gCB3BAIchh4J0DbTGJYMgB GMbDGIxBHwQBMTBBJlYjVshBB6iCF/zhXATDNiQDKajCzf0FHFIDC0jDcAXDJ4ThsKRiPOT/AA5Q 2CPoXS2MwBsMgB5s4h+WgxowQjTkQySMABKoQCiMwDjcwQuYjdmwAzkIQogBHhP4WpaUQxLqAgDY GQDsADEkIW3RATd8gACwQDTIgAykAQJdoj2gFS/UwTZyYjDIgw6wgQd4QCpMwR54ANNdIzEUw589 YJak4g7ogi7Ew0YOxjaIzipIgj6aglOqwizIAnpsAyOYQj6owD2YggsAwjiMAzDIFHuxlzGMAyYU nevph11ow4DxzFU0ohtIIw7M4xi84l/wAho0QBjMACmwgR5wQP8shgyhwV1Ugg+4kDb4ggKQwjeN wDVYwQAgAgQQgS2EgwggwCISQznw5Fp1/2HG3Aw87sA8HmXOMEADbENXBMBSQsAAEEFRsIBTxsAB mCQLkCQLEMEAoIKTrdcNiI0RYEMePMHOnCKUlINZfEU5HthVFMs8cgIx+MI19AFHRk4MOcAMeEIc MEEwtMMssIA7QEgsWIcXCCYl/AIP+MLPLEYkAMIShAAi2MIAhAABkMMfXEMFep81ZkkQxIsbyMtV JEI+qEIAMAIPlIMPNMAqLOUf+EF7PoBkQgAEKIUqeAAHQIA1+EEFjMMKxMxJERMfWAEsCCcgxsF4 tgeWFMM5JGEj9sWpeIEqRIIANMIJUAIdqEEVVEEYOMAeEAG4RAEUCAQ0JIIGBMNphIIeEP8FOOQB FfQAASiBM7CXMxBACsSKZt7M+t0FE/jksGAACwydCHRAcGJFFYiACXBVMJIDIJDACEwBCwQAPJBA V04AhorCETCZE7RBBDiBFOTBGjCdwoGoX1CCGqCBluzHHh7AmnrcFRSBkTTiXDTCEByCCDSDC0Qo BIBDJDCANtSCKjDFHwDCCNzBOFABH4hPLuRCK/ABEQDh6xXDsjCQlsSANEyPDoDAEFBkk3yAOQRC IIxAIFzBECQDCszAB4DAFYCAAAjAEFwBPojCdwlDNYhCK1DAEyTCrv1gOmDhP9GFqyWCCiBBIBQA CFhiNZbDJIziEFokVjjqEAiAiw5BJdr/QyMUAQiAQBF0wQzMgLLqAhzAwQ+0Qiv8pq3mjkCdwAxQ Qqxkw5bCQyCEwcANCwrggWD6BRNogBruISi8Az7ggChUQwJYASY8Q30uHNARwzko2F/4AQFYAQSs gg4kKihcBSY2gTJeJxOcQwPmxSc0AigCoSc441VUAgrkawIkQBbQQ59howSiAJbmhTW4ADNwBcHd jMzWB2EKYQPQwiLEgDns6x1YARDkhNv56WW6xzn0WVz0gAVQQTjUQ0RmgC9kwCRMJCVkgBdmJlZQ yX2iQBJeJ9JiZhNUgk+mQwekQQOCAD6k2ohQzt1+39LihTLgYTJqiSDxBTFsQzAwQhBc/0ECTAAg WIEtqABXeGPgBQMD6ARCsIAx8ME1QGSU0C0mlkMGZEAhZo4cZIA2TAJgUMk5bMPnyYHdLqIcNIFH HkM6pMMWmMM4jMDjxgDlhmHjRtXreaR98AAjmsUZaMM0QAI6wAHn2gIhjIKrSqAIyIM1mA0iPEIZ 0IOVxi4lNEEGaIAGnCglHINFUkk5FMMQWiOjEsMnTEJm3uclxiyrkuwk+MIVuMI8WAPIuiPM/qHo umNf1G4wBGoigAA6zIMJgI4qEELIiqxeMEMgoAIVWAA7PMETIJQvUAIanCjuYkAxFMN4lus5UIIz YgDd8iTfzgUYSsn+WuMLo4A9MMEWvP8DOgTCKnzBzQHlMq7VCSQBEhgOXYhtXpQsct5OXgwhYfhC JDBCLPRCF+iACcADNSgucdWFiKJHg2lFBjAAmwqBG7gBFXgIG1ECgdLwDF+pD+zhYRIiWjbiDl9F MATD2NqFz0osVthDGGAAKAxBICQBI0CtYeTdZl5FE8xAFVADAyvjH1bOsVCCCJ4D5wgqVmzBDOAB 6dDAIpQFJy9uHEBCEFDOXYxK58iDPCzBEpBDCBCCB3jBGUwCJfgAJcwtE9AtHXghEspu7b7wlOws NtbBL6iHNTKiHFACFlKJT74w3toDHszFFoCADkQCDQjmA+sdbZEuJDDDXHxpKIpYMaT/A5YEr7GI qKpsBTeowVrORTlUgujQQN0pLjHwACOYwBvogUEowgSng7CagAk0Qzj8QTjwgCqwEwL4gAbM7dwW S+wW87L4bjmcg/z6ZBKCohygALkui/32ZBMQov16YiaGAR5kK1Z4Ail3ACP4gsBF7SobxoziQQdA gi9gRZJsMgPjxST47l1kAA2YQh89ybKkCqCqQQM0QDCggbdUQUKygEsMGBMMQRVEwh6ogipMAjdw AwugSDb8ggb4QvwWAyH6LltnQDZkAJXs7H3qh4iWQ+YwKqP2RTRL8//KQRhoAHF5wgyEgRoctgZg YQS3wyrMAnjc7zF8whY0QiPMQDLg/47dPFUgDvWSvEc5aEADzAIkRzEh1gUGdKGJVsIHYLAHHAeT oIBL4wE1yEINmAI1mEI0+AAaoEEw07Hs0q3NyjXsOiMjMgkTGKyVJicYMkETPCIjdkInVCP+JoMG YAV5dOEx8KQndAEid4AaBLIv5Oo9jPZVyHQdOBsxpAELREEsqDJn0wUhEOd5nAUazgICBKwS04Un BMIdqAI03MTIXM0kbIA2CM4itJEiyIIvvC0PALMvnAESFoOqXOmVfiEAL/dEXqcXLjdd9PAidkEY 1DTQTWl5y/QVBAIS+4VMz8UiUIM03AMXZKsUN2yZ9cU8c04+UOvRgTESsIAiZAADZv+DDyhAcSYC p3xBUrPA+yzCYeY17fgvGFpk/fI1I17FieKtM8YtTz5iNQ7zWSSDACiAeTAqtJH4VYCAOQQAWo0z AlyEi1+vD0QkZ8eBXbdfHIB2LUSBjjfJsJSDEatA0U3CL5wyIyxDNyTCEW0AI8iCAgQDHsjAgvfy HPgCD7h1F+5Mld/ndaaDweZFXwfhleqwXcyAADBCIXCiDwIwMTQCCJAC7Xx2OlRCdc+FMvilKaAB eGRAJdDHyA7LNT4QU9OWN6yCKsSCFMdBF5jAKigCReqvLgiBPlbHItCAAijVEHQApcfub1MC/vqv hPNCsWAmI2aAzILiOTDgUVuj7+L/LWbK7kTSgT0wAwuwrdFd+FzogA4oAmB4AmGX4lVAACL45Rew AJGTbPyaYn5XyZiDMTnSlkA1gVSwwIChRxzgQyYkwBLYAkFEwwZsw4JPQjK0gw9kwxnILh0cAzbf xf429zWfA5ZacyXchU924f+SrC8QRhNUsjnowD2M83rghSdcgQ7ANF6ggDigQgU8QChAwzQI8lUE aR6LLZ3bRbhjxf5asQaEOzeIgGMzo7IJgAnUgk7Y+VUgg8VLGT3AwAbMgA+YJwbAdjL8OFrKAfUG YRzINahHsxwsbTmgN3wQaDLs7bC+ETPjrZlfpieYQxI8nHuggxRMgC1gAmXIwufd/3kwyPmwlOsi 9vp8MzeWJoMJBMAzuF4dJAE5Tk5HEkOcP4IuSBkUyIIimKTbfoU9pIE2lHwhU0kGGCJKc3QwLwsl fIIGMP7/2vX9LqIWEsMZ5OomIoAfl7F7eIKxdqZfPMLjh4AtUMYXIDGmTzUaQ+DNFEMl8MUimMAT 2xZQkhnexkEVjIApJMIkmEE01ILqxzknPLstKAMv+MIGpEE2MCpAbLFHZ5IvX+WYEIszKUMcYsSY MMFArBilDOWIdXIYh4nDh8UeQoRor9KkSUOu3IPBA8PEhAlDPowYkyaxDx3ieKQZZ56UCX66wVJE g9HEh5PSBcvAy6jOmhCdPpVKzP8HLwZCSCCIOvVpToXJTKwiBAMGoypMKqHxhQKfLiwDlJnRlozR pHJ3mdgLVi4nk3OU+OJFGAcDDzmTHmKkCTPmTHvH4ugI9OUMD48zF3OdOEOHNgxb4/jqOeHFg2eK GKXRRthhuWDBfPA1WjPnOa4xo8rJICeyCRZmWhJG+LRj13KTzuhwwcIUrWQCCpbToEGAqwRYlD1L pM2epQwY7BJrYi8dMQy7TfLN0JCJHEu/JsVBWM4iRJAyI0Ysh4FJsUmNzKmhnpYeymYUzES6jZgt rmAmm6k2SECUCShQ5wAzZFAjmNmIOSeYbXjhBbSHFlIopK2kYqKJ9USAR49sMOD/RaGmTJzRqxNZ O6MKEVT5IptsoCHGot3i+ECXXfzQ4gBe5DghmUUSUSiODOxBIT7w4pBDjnJ88EHLDHxoKb+QEGxs zHN4AUGHGBKJjyMS4ZSppvskAqGKRH7pIBncCFtEF1GMeUAQ4KZMpxwzPJKjg2B+EdGjqBRT8CHL amzvF1TG2WMULoBriamWCJSStRvPM8GEfGJpKT5KugxGG17mwWEeK57BoBzdtrCEEl8M42GSLlyF ETlZKOEtDh5+8ZUJuy4iZr67tkSov5A6SceXAgJRIZZsQuRhPluLeWmmMuXAYAgduAFFxpjOgAGa J4Q44ggLKHgCBhlt1eAXHyw7/zYYNRjRRpsZSYyDEgU3MjEnnYq5IgFxSLCCA3cIqQcWGGJBgFum CIsBgZh44MUBIZKoJxYzeDGDCQRi4IILQejRYxdd8rBFEAzkiO2zdCrRJoOOPOkCDxqCIczW/X7Z QBtf7AIJIS3z+6yYcKWFiAkUQJhHiAEwUSaRRBBAubBJErr1Jfwg4gGlDaJSAYI/AGHnhhWccOQG CpTh2MRKgjk4p0nACyaNMEPEIJtFYtkIxZ1urHEIV0RxBBt2nHGGAAqssEUZWHjh1i7hzDMjFlM1 CSWb+B6C4o07sMCijBGESGCXJTSJJQYffkHDy09QQIEHSn7ZkpdPktGGhzPi4P9FkWQUQYw1iKpO 0Fk5iikHpEmqHwKdBMjJ/AEo3IEBFjN8kbFELaUnJo1ADnE0pnGkkCKH+aWIIAJWerDiiQvNb0kD NFgCJ/kILg0KUIDuEMOhp3wmJzQSSRzwIQpRyOsIUljBJn4ADArUIxG88hZ/JsGFZbhgAnfQXAwQ hYE7TMAYeVjCEv5gDQnMQxS7oEAKDnA0MP0OBRaZhLfkkJgNJAMP7znDBnwwiSA+JAMJ6siYRMIE SiRkPY3ARybg4AgD/IAP7CAHEepxgIUwRk7muYI5lAGDz4REB8IQhhOGAQY5rqAEt8CfFUKRiOCY iBJpQF1M7KKBYizMJFdqXMH/iHEGLzzKITCJAwhwUA0ytKENLWAFGFqxCWxQoBsr+QxyomCNcYhD FJtwhhXc0akd7EAcN+iBEv4gAQiAYxc7aIXEEKAAbZxBDuc4RzlQkAzeUIoJP2PCJ+5SH1vx5y6+ OMxwmDCf/kjkVuXoxDm0oQM4wEEcrWgFNnrwgjyQYxRMcRZjrpQPN5gAE88ATkgeUYI2RKAEEQCD EcBwhBKUAAwEsEIafwcS4ShljwtjoEOAxwOm8QBGl3FISygxqpjIwRe9wEckK+kIR7ziniuwQAiI wIsfygAeE0hADuCgixys4G7d4EI2LMiHGziDHOT4gx/+cAdd4IAKVhhUNnyR/4GDHGcOW9gGry4C Hqb9QgNmmAQKLDGHX5xBA8EAXAZ+uUT83KUcnuhEMBeBgZ3C4QfYuMENgEEAJZDjAVrgxXEeggFt rAJTCUgAAYCgHXhe4BZvdAJHS0FJJ0TACPkLhfiygTLEKDQNinBfTDLAElAlYhtN5JN51riwo2ip HF3AhxQmeIQVaPSCFrBCCmLBA1mgYgIT4AM+jRBbMOQCGANIAQ5ykAAqvAAYNAUE7ISQA1F8lAgc 4IJIKRpEW9XBMkyRg1/sUolyJYYSXTiB9Y4TzY4s5C4ccUgnPLGFc0AQBwnggwVuYAEqUE4JuMjh 09CwCtdhgQp5cAMVyNENev94RAfV8K8o4vdfOKygGiUohQZNs5IzfIYvGjCURGNyK4+AKVJT0ax9 4mCGImAxASzkw3l3QQVbEIKh2uymHFEsx1fkggKYKAI+rnikeWitAEkIhAl0wUp/puBrQmWPs1BA KJhEMw7nQIFu4tCJGfzCg8U4x5WiObWIFOMwcfjECYrhCXy44r4ubF0eqIAIeiCAEufghgnK8MIs 5AEQ5HBGHl6ACC+EpAjvgHFb8PGOMz5CHP49Ah9OqQkOFCIbPPgODxIRDEZobCJb2Y9XsDojEe3R WWuE03G68A5dJGAc45iAOCawhAcQIgZn+AAWxfEKR5SiBcNgdQRawUli6Ib/L54AxQbQACNftOMR CcCBKPhAgQc8QRA88JWUimEPDYBKJuF6SBMoQTZiZCAZG4iISWBiNvtAhA7nmFoXHsGJMkgAEdb4 wx+yQIR78FIOj9gFFrIgTlfKjR3YeIEgQlIOXxyAoTVwwDRUUAgWHAJyEjzCD3pQAVsc1lH+4oYs YPTYjSTFIxg4g1AbLSXiOKtgQzAHOlzBZUToIQo+UIQvIihJMuyzBMKIQA5uQIAH+GU6FZHDBtKQ Br4FowkfSAAcfh1sW6gAAesazgzw0Ly7XGQ/CtlCGNIhHzlsAZk5kdYJPIGZhGxBDk0QSSPOKIJA CMEN12CBDGLhiXKAgBNC/8gDOyzwYQtgw5tLUEZMKMHgXzCCAbOoRQMY8J9M+LcaLdhE/rrmThHx AgXckMZSCEMixmQg2n/rWwM1LpVGb6QljODRKLxwOx9kY8OSHMM+bnGLeFigB37QRJbOsaVi9G43 W+B6OTIwhJ2Kwr+x7sYzQqTtRoQB4rwIamJ+hlUUpCOiG7BHtIpxgjhMrRNacognTpCfqe2nC0MA AQgg4YUFbOATW5jBO1wBBylsYhOOWAEYxNHTeoSEISbRBgMYsAg0xOB2ikAAKAavGtzICcCgB4St G6ABBrIhEbxAFVZhClggcQxGAxAjJDKgEnzgDBTAVYwt8uKENhyCF1iCF//SgBEUIRa85Hd8ABku SpJKgAxyIOEGgAOeq2nkQF+8LZpuJVzswdfiJx5ygABsIBTOoCCuZB2qwBsWARqWZi2sxNnm4BMI ohzsIaKoZ9qg59o8wRO4Czwm4RzogA4oIQw+QBG0oQnKr3euIBMyQRxAS5J0wQogQBFCwuL8bxsW IQNloXlggNS4oA5cQZLcSBhaAAxi7gG6QRPAYQ8QYQ/ewBo44LDOoHAe4hwaYC8oYWkUgQHCIQYa bnE0qxyiQRvUgAYU4QwKrTJ8AQHqgQV/TQpawRlCQA8KoTCOxxfOoQnkgBciyyF+CHXMAehSKgfE 4QWsABNg4Qtqge/W4RD/roEDViIRxIY/OOsETgANtGEDGIFpzoBpTKIY5sBWsi+aEAMcqy8DUGAG urEOtqALbM8erAgHIqka4oETrCAKfCEkYiEUCkEaIC55GEAV9mAPRuAO/iBzrgEHyKDw5AXAJsCL AAEQ/gACJOEOAEECwGERITARWEOkCkMbfIARaIERZOFkUiZUFobzCsMXOogRqCEKlIEL7kEGmGMR IUAJ0AEHJuByOCA7xkcWtsEHwqUJ8MAHNkAWEGAWHCAaQiQQ7MoC2CEPyqAAhOAOrMEDPMABZmEW QOAQWCAImMEB8kEaJnESROouguEEfsEOwmAbEOAMECARjiMwfEAivOUv/36mGJqgC2ZgAxKBB05g EjzhynwHFNAhE+SxDB6AA9aFGKzAChqxEGKBF84gEsROCLCAEzqMCgjAGCRJXnLAFTghDzjBtV6A HBABHEbgDxBhAGyBCDzAFKbAAwpBj+LKVuSAElBADf6OBs7OV4IhZGKEB7YBgHjADFiGGuABHqxB EpAACZphBEYAC+6ABLIgAVhKCEOBOkdgD+4BAbxFA7ahBrzAC3RnAQTAG6RhBOYBHVzHDzyAGmqA GcwBFSRBH4JAGqqADaCAEGLhGRYgP2lBEXwFJCqiDtZhBj5AB8IgGE7R0MqhDnblIIpBAw6CGLwq Qu1hG0aBAxRhD2VABv8YYRYSoQhcQRdC4AHuYTZa4Qc+ahmggQtkQOyuIRysoRlaZx5MShRwYBeM 4QVoqtyygBPmARCIYA9MQB78YAAG4EhNwRRUQRX0APgYaCIYzBdEVC0m4RcqYRvUoAEaoBZqQQ0Y QBsUwAtMIQnkAQsk0g9wYZYkQR5GwNweAQ6OIBcSLguWoAyyABxiARd/IRlUIBQIARruQQVkIQhA wBwY1Q+W1ANUwRQ8YArYwE4YoQOuAARSIR9kQBY8tRASVQbO8pfW44cwwPzCIAzaAVVnoHgmgRIs oSoMojAutQoEACyHQACYgRRIgRkgIQAOgROywBbcARZCwgIsYALGYQD/CuEMRkYIrKHcwOEayiAJ riEINNMN4KymYugPsMAEPEAZNCFNsYA1mRQC9sADwEEVwIEFoCGHvAIDyKdLkuixWsLQ0qADvCE6 R0AeACEL9NQPECEEGvEaHNUa/IAKcqAaPAoRBBYzuQAkG2EIIAEKRiEfVGAUFkAb7EAOwuAKrmEg F3EP9MAUrqEKoAEBoqEdSEEAamAUoiFEv2BEDUEaZMAuIsITpqaX0KALeoZ8TqAXuqALGmEGhiBV AW9EmWE/r+EaICEISAESmOEQqiAI2qEGHGYe8iskeuAGJmAe1C1jrkBrRkASRiAJqqAdCGcIHmEe UOEO5DQQ5LYKVGEW/0S0FlzABCxSYCEzWinSA+qh0ETwMxQtBn7kF37B0jbirbJBGmzsEQJBIiXy 3KwBHCCg3CTBGsjBDXBgXqzADwDhEZghFnxmLxuhEYIgCGagSrRkaprA+3RABwTgEA5hCBphA/Ag GXwABTpgdgUAEkxBBe7hHvQBVGtAFsAlIXjAB1IVARAADZKhDk7gMNbDByKrq2BXCALhGg6BDdgg CGogCPBTH6gBEmoAa3VhAnDhWPlgHq5BGWJBEbIBAXxhHUhhCGaATVLoUU5gCIZAXeT1PLZBAWJB BrihA6pg7EgAEJbApuAGEjmAA1hgGdzBC54hG7xAGhCggF+FKUwiDv9iQRZqIRCqQAa8YBYiYRX2 QBImN3MRdgnabAncANQAQR50QI0Mo7twRCEQhIwapxNgIry6wB5mgBlkIBqWRwYQgBR4gP6IIT00 wiTqwB68goy4KgzsARRAgRmqjRQ2YBtkoEy1AQ0+RAaCAP1S4SHSQRzcdxn8k6EMbUvAo4lrRDPi wAcMwhcm1AcEwASEYAQGNhyaIYbIYQmcAUgr4BiVARpMIQpYQAWAgyl4AQFqQR5MAA92KRtEsgOo YSDL7Q/IwQ8I4NzIARCwQEclJZVVeZVZuZVd+ZVhOZZh2R0E4QlGQQW84B68gBC44D/JIhYuBmxi AQaWhDIRABY4JRH/VgIBYOBrFvAAJsEMyAJILuQA5jcbDoB/KFMBNkZeJTmxEks4FyJlUIYXYkCy eCERgNkMvgbREqsxNS4lPSWFJg1fiMGcRKWBNCtGrDQqvCJ5vAXzUrKOzYMXKCEtFKYOCUZUGq2e pSEAzEAQskEX4iEedmAXiAEaCKFimrmZ+U8asRkGniEWEmEBwyYbnkFJUMYMsoGkeeBCCu04YySb k0deE6HUmEIaU6aYeYGkPaZTWsIMgAM5QySdE2F8MCYWLAaeUYYYcOACoPoC4mEXvLklfkRsPkWz jEaek0dKPMUhiIAIvvo4G+dR6rDRfKEEZ8EXPsNwSvCo8FgGaKAB/9TggAKABFCBBCAhGohBF/bh AnSBE3Dgrx9BEKABGrB5pA2VCxIBGjImpcVHEJRaEDjnAJR5Ac0AFbVgpUWQF+ohFMg5EVImG9Dg ALRjmJvZJBPhDLJZGmFAqO8lFkj6tXnhQm6asTGGmGMiZYhhBy7gGoiBDXYAAOKBGMq5cBqIY5KH I0HFKGIEZf75M0QEsxzCF3ygRi4sJDhmODO7FuqWGhgBRszDaFoCbKCUDaBhqXmhDy6gDGKAgnkB Fp5gGVIgRqEhFJ6BC1IgBkYamOuBC55BEAA8pfV7mBPhAC6GnbWALBjbm83gAGAgjEL7wLkgm3Po Qh6cnS/GdqDhqP8VUKRd5rBTQHyQGQZkMkpCQqh7ewwe4ViIIR5++7mnseH+Uqvz2YGex0Y2IrIQ aScYhxcWoRa8YEmAgwcQQBEagBbC1BTyQRZyKEYaKB72QReIAcL7YB9c4QCUIQVSQBCUQRA2Whmg ALFH2gsE/MC1IBSgoJdJWpmb+WvoFwYEwbIPQAu4IIzo3Axi4B64ILeFuqQP/Gta5mVUwBQUAQa0 4B6G+QnqoVDrQQXWXJ0RPCbqfMXL4CFyYB/6QJqbubk7hWMcJTgUp2AWZtIUYrpnRBsqUICc5RPG W7rPQBaiwQu+4EkdcBWoQdEJYQEI4cjRoFNYgw5zYAwAoNj7YBf/zIAQUsA/64EeDDUFQkF0oCEG oGEU6iHCITxjRCcbyIIsIDwGJhNlEJ2dFUG0z0CataAeZAAVYQEDMFxE2PlrfBkGwFIGCAHBYSER FKAQhlcGVMAduGCjUbxAZGQHTm8f/prKJ6HQcuJTmlvU4cTSPhBOAijz4uAMuOJvzuGoTuQ2q3pG rNSqxZsYlEEZoj2uwJwDwCcUwLxQ+U8Q6iEF8lsQoD0UQiEWuKDEIxwBAvwAGBsWYMGwuYCZsRkW LHyl+3tJit6yMQYWHJuZX+YZ3CEIIoFkn5QFwtcQVMAQpiBKVUEWYiIubTPFFZBjoLvURSXU/dnH b4MHGICBaIJL/xoiJRPmwvDZRkIFAzRADWThHtxBGUzGC/JhFKp9U9I9EQiBUL2gHuphFKBgzJ/B ZIK+ywM84GWBEJT52vucHlIgcP/8qCGcmFl68Z+htVs6G4K5zp8hwp9AGZ5AD9igBlJhYgQhFBi9 9gUBClLAHXBDocB5YxawJfjn4asUs2jjAxdnt8VUAUZEMyatnzlPYQgjEepBowuV5qGAzw31vxld v7mA/2IhvdM85hn/GaBh2Ueh5NObLJg5m2FBY0zbZQx3fBD8Qr7gHoz+QuhBslf6wS8kFgBilB5T 1FjoIcKBAxEP1FSpmpZPzxRTxCoSw4CBFwYzvDpq9IgxTpyPGf81xsEQpyLKlBaJiXTJsqXMiry0 vZwpM2ZMiyNvinx5Mg60USnuLbtX756XejC41Bt1L0U9QimeKLsH4xmMJ6mYBUnEhdAoQjAIhRLE hUsiBGphxIqVCBaMA7CeCXqW9sABM1xmfcn67NmBRDG+sCjEQoUKFlE4jFLGAcqyVGx0HGKjjxmb QzWiQGlp5gBGXmfOjI5jZiPK1XGyMZLBixivoDdV4pyJYaacSbdxpqzdMuVK2kHrcVkGBYoXqvXw Tq3XnNA9Ql6ghSJUL1RgQXffEkIA7S6CWDBiIMiGwMyzRNnOhE6UGpYWuc9iRevAbBQ0uAfG14P2 TF2CKFNPClz/QFOgMkUlp4yChFClTCwtacQDfInwAkM2GZlxUkfC7fSTS7lZNKJLLZXYGyV0mNhb izOxxBJGFRF1zyhthUWWIERxEQM00xH1334wQKPME1rBwNZ+sZxxAAwGwgBLWjFkw4MXMSSSVXpm wAcDDNEgyEV9R3KhGHSxXPWUUssoMwoUo3gRDVEpvCldS7HwkggGPCBwxmwnpaZRRhjlhtJFL60W nIu9xcFIGigqapuIhZq4mqAYGPdfIQUWcuCD0oEnw1j1QPFdLNDoxUVdPCKoxTPnwUUeLGZk4+qV eMFgxqz8ZcOXlVHiGosiscTwRArQxLBcISoUMoo7HKgAhTtE/yljZQoq3HNPDC1lcwAvk6RWEi+h 8aARhz8VChyk6hJDyS+/+QZpiCddJGNusfwny1Qx3KMYFykQklZUCiIIcHle3MoFDPWQ12WXiSQy GFj1rNUwF7FwgQAsGh8QSlhfyPBMPXLBslc2E/trnMUpuCPWPYXcQ2pSXrw5nYQW3ZkRryHxomFH FbK2E08wCR1pTuWko0YDtdSiBh2TBKOGjIq+myhMMJ4kIzT7PYEdDIJcJ4sXYYVSoBdQIPXgganm CoMXengAjVuEPYxlWnLPlesBCZuRsbiwQCNNO8sJ8nBZMciSAgxaGJuWj1AU4qayzLmTgn0qQDNh R3pd+CcPg/+KO9vQi1YEokxHr0LCONhgYwEwzgCySi0BULIu6SSeCONKxJwBjVMWx0J2LNilgBZe gkjH5ij1KEOIIPcSkk/CWihPHl3icqEXAlr5x0UhXzDAyCyMLBJ3PbKYIkiTdCcSCxQqtEmUqW26 M109KgwcS1XL5FOILCfm2hFBaeQis+EFD64mo6Cp5DcKJMYkakECPoDBCGIwghFY5zpABKIWtauI Nm6DtQ/JxknOu4fdFged5jxjKc+B0sWsUyBC3AoWglAYxmIRmotB7IUyoEUkAiEEN7jhEY8IRBW4 kQ88MAJ7DuPCcopCCGjlIx/QmNkoVNAYorSJfy8rRCG0ZRH/0XAEPhsiV6U4cqjcnAtEIcqJLxpw BzCwYhhOiIATnDAMMeQCGzewQCDS0MB4Ee0n74LCW+4Riic4z1NkK1YMCgaNtIElTBeLxTO0Rhf2 wUBzPBoSArRBAx1wYh6cyAMBKkABCoSgDDoIgwBqsJ22YAsqMmDWKKIwMxUsgwMpmBM0FOAjLyAO GrKAAWg6kiseZOMjegnUoHI1qJzwZI20wQAlGkCFOUagBCUQBjftOIwJ5gENtSMkixbFi/FoLUzU icGQ8pKIX8oiFtmAwXTsgh2lDEstENuLuA5ALln5YBHtCAQnWmGBGygUGEsghzWsQIEyFCAMX4IF Ai7qMv5F/8MLzFrWPRr0rx4ZCwH1g1YVJ9QtZKZmJM60FE/QRUiWYmAS50iaGoKhgQxkIBgBMMYw tlmCW9yCm98cRivKMAkMMMFQ5WyRSLIBvGUE6WJcGAteTMhEaCgiTNlgT93YEoMm6SoG2ihHhcpi QkVUwQ2tWF0uLGhBC7CDHAR4wSOGEDYu3CMaSvECSW1EFS9MB1uP5GhU3mQ2WYQKcyQKTa4mAToP 4SkkkyJRSEQyCR8ooBbwuMM4fmCA0E4AFSRAxQQiIFShBvUW+wDAPuKBDmYsQhsKoIEaGME7BEwi kMHRyazysQdwvGEEWnuLmKpICGhIpWHPkEUM3jMeXtEFSf9YagoDGhCAVawiALUIhgIKoQA1JKEV EzRCLsRQQQvyERh5KEAQwiYDBcjgkIU4FiHCpoghPWgU0YCWdJJyD1nUNwY2U4m4zDAJyAIqIyIJ HYp2UqhJ/AIJ2GAFavfRWgC49hYR2GaGXYthDV+gDx0mamrJIAV4IOBRLeIFNByiiinUQB+4euQ9 eoejKlYuFHMiSzay0bt6eKG6TYHYGdAgjVU0gwoWaLIF+DCBCYxDuyZIgDiMYAFsnBe9erwgFZgR yf3EIAaKkC9fZWHChXlhEWgWFjGx9SwvCPMLX4hG5vbkC89NwnMe6lCJ3oWBZWKEB9qgxThacAsN K3rRjG7/tKMZvY8LSGEKXNhtiQ4cBx+gIc9UiklIiJENiyEpLEFOnyCY4lgEVHct0FgLA2LAI1kE ABVUuEEuNhHaXK8gBwmYxy5ysIK3mve8rHjFCtDBhiiY4pHR4AI9tJCNRXzBSjeuHyE2Gg1CsExr cDqcML1whpawZ5mTOA+DLRXNRCVCFtugkCI8sAIyfPjR9K73oseQAwsAYg/5GOBL29jblJgKGgiA ku/qppRXNQUaZ0BPk2CRCKXE5Qt3aLIBjlCKUhQ7468QAxiwAYwbUGECK3DEEY4gBV2srhV8MIYQ R+kGIciDA/TI0BnC1iNkfTGSKXDTIYJQufuOJxEt4cEB/+NgdB5M4sd9hqlwJsUDXxgQA7EwRh/s jXWs98EVZYD2cM5VNdtZJGFaa4relkMeuj2jq1lp2KlI1rbouAG0jiiFE1qQ8bsPgxWsAIOTsWHB kk+Q72CYIB9u8AJALOEFWAjEFOjRH1nsRxZfgEYhvjQUQzBjAWG5B3ki+YyiCwqAfFYpwM+1kUQE YxabPMAzyrCDeWd99vvowzswoRVCfnpdcQNymLbEPrDAZWGxKHirHkaDJCSBBcswRQBU8AQO6EIU dW+B9UsxjOyzIr1wtaAYWGEEVlif7xXEBjssQAV2vIAKbvhDN57wJuRAxX38W8Yy3lcIVTSjGYEw xyMKUP90HKERe7ZMBYQRu2U7vwFBIhANLCAP4zAC9yAfT8AJ8XABs4eBfYAONlBDZvRg59QiClNP E9MlxiUIfwMDicADVAFtiVAP3PE1ULAHJiAE8GALNoAOOOAIr8CDO/gKfEd+6LV9XCYGw0AGZNAC P2gEH2cBefACPcAO44AFiEAE+tAmlzcKaBYE66APUaAP+pBIT/AE9MAd9FB06NFVXYURPlAus5FA 84I1s2EGoyAC82CHpCUJRNANRfAOsYeB9fZaWMABoXAhYtdBKag3iqBqXSIYcTEfG8MjGdMldMEd o1ADh3AFgRAI1lAGupADoFUKLVANOwAG30eE2SeEdNT/Bnj3gytgAT3QA86ACvNQBuqgBTVkBrFw D9rQI1XUIzhyFQcCFwcCGrzSYILyE6AjGtMkIlhDF3QhH8ygA0IwD6gACHxwgX9Yb33wCMqAAKHT QRaBJYqAJe+hMZCoF1qQFYnDBbyCJ/4iQ88QCsoABJSRBHtgBXnwiWKwCa/QBsIQAcY2QQagccV2 csPQgwbAB6wzDuYwhpCnKtiiAAggTBAjHfdwBj0yHkPSapkzGoSyUiHibzkBhyoxKBCjBU9gC1Rw ddpIb/uQCd2gBZUVjrAAFxfCC3rhWIPhT2bQJbKSCFowGKkCA4pwAFrQHF/TIJoADuNQDRjXAncX lXjE/3fGdgQrAAabsAkrkAmtQAXGwAlUkAUQAHl7ETGwxitp5xQElw0ksyWLGCDB4RGGggHdwmAg qBO9ZYgXkY7XEA8u+WhjoAtaYAay4AGxMTUzcQYQ01XP2E9NshewgB1xkYJmUBfyoRV6gR10YRdP AAQDIArV0AL/KAxt0AZHGE7oNQxHcEGrk1Cx6AzAAAiA8AZRQDJKVyHYUz23mT3PWHyLqRe4IyKk 4xPNCIJqRJyBhBpPgAlwMAayBwBjEA/xAJ2OFg9FQA8eAoLrwjMQkyGciZQYqTjAxwvnGJkaM4lC GWhuATDqcAnoUA3VcJoXcAFkEAFH8AreZ3eh2AKOwP8KbwVywPACS4AFe6AOkKeCbLc5gfFPOckt KcgtZiBNnoYSJkEvlaITvHUiGLEK4/AIl3AJfIgP+PAO72ADNmAFu9CS9BYPZdAN9aCh8YIkUHUG cjEYWwILH5E3OqmTvDIXdBEKemGWB0AP6iABrhAPfXCEZMBxYJAL4ncEjtACwkAGTqBxjuAIIIcN EyAEEKAMQhkaBTQrgBJAZskROjmSC4SMMBJAChSj54QBATAOQrAAogE0hIIBYmgD7+AKO3ABGTYG F7AD6HAKkAcj4WgRXXUvKbhqR6mTdXkAvJIr9cQeRwklQqoX8uEB8mACOsABp3AK+JAJOxAPO4AD OeD/CnlgAQQZlaaJd1HpCB9nDLX4bJkaqakRGmaZmbgaqSAhlyZxQJIyEttJNLgxNDFgWuaQow82 HOIyEnpRpGtgA2twClZgC+7wDCtFrLWTkyTTVRDnT2bZJZIKOmZQQ90SF2IUGrBgCibwCFegD0BA D2OoDuoABEBQr+ogrfkoDlKwAjwYisIQDyvAcrSqBY+ITCABmQCkowXIESdiErkSFEmVJ9upQALg G7MwDhNwCIjpVFVzKHCCRgCHqMRwq3thmdKVq7kCH6HBLR6xJRyRq3ohCCQwD+agD0/wiD5JMneB mYJwoGtgBY+wC+KQA8AmDgnQCm6AC5gglChLF2TK/zNtiCf+lJN+I6EWIYCFkhEmSZwXsZfEUA5d 8CIHgAoJcAUikbUgBClJVbK3kSu5mjMoG6brqgU5iSsAlCuyIqQqIAScAAJP4JbP6HoPoxVaQDbP MB9Fegk2cArf8A3WagvySjKVqzkCmJNQmzc76k9SUxH+ZEYicW6kgyjy8iIWwQvwMAHm4LFv6yJv eroucbV+E7Uoqzmuh7klYZk6CQss8LeHoA4aQ5gfUZ6ywi22yhEHW7mwQA9EMR/NtLkpFbdxe2AB JIChMRIosqxuiDX00iHKCbcdOg8L4LrlCyl6UQ9Diql8qxe8Iit4MhdumZOCsAomYA7YebC2uxF7 Qf8u7pg3/6S853hR9WS7nMtMgysIu6u5CdsSJKOTaFQuLFUbGBAFfzYTibAK8iAC0JAu5uvBqGuZ lvlPZkkyw1uuDFsuBwANDmAZoQB5l0u94rIR03tg+/vAAtgtdhmmG7KjISyz1hPD+oAFOwEx5SJo 4UISJHsbGIAAqrBdrfvBUUw6e9uTOXmmDEsuHKEaM3wAyhYEOhsaPDzCCdtMt6u3e/vD4VoX3YIa 0wu1ZjzGyCRukZmpeGIaHdKmYNsiGJAIMjANNiHFgUwT1yuzBxbG0MTDJYERTcIFLOAFg1ueuBKu VsvFK6vFHXEhHFIuG4FM+1u9zxi3g5vDmoMiUKL/MYngC/BhdJ3shiFZNCQJu4IcjpnrN7orpOCi UhIrQDF8tXFrlpEVKL6so5rsWIFixTuao+UqpnkjlJ2MEnHbEorzBHzDH4pgaSvFxETXwbLMzbgx EtS7uVdcyJjGyVWswCMss+ZSvWSqxQC0If7Et5pDMv/EEXwbtxjhWDvJyS1xBoFhMTEwkYpAcDi0 JbiiGgOUbqQTDHLQzYIMEh1CQDW8EtgsQFoDEsRbyB/pEUExxomMwpvrJxnxy1tcw9n7OZjbEhhz HvF0LEPnFnKTTBUaE1Dc0LJMzyHsEZeb08qYGnYpHDv9vgE0zC2lyLTsIaOXziRMuPLRzLkoGhcd /0At0TspaB6VlA2KUE9pYTHs8Y2TUBphW9OBvNMFJNRajM9C7WCrkdNqncRaLFPNeJQwu7+4etTu XJc5vZNsM716C44VESxvUR0L4xSKoBUPgiSx4AO+kFSKwAPwUrLFENbebNIM9hsmMRoyDBPoUqHo 0owmYaEa7VhxaICcjMJtiKuAEsZ3Xb2ZOxotgXmk1jgEEklO5AXa8EnakGfhFsuxG9ku0hGyK5LI SC8yHC6KPNGD0qyU3RHakA2iK73lktFFvSGgM91WTM8NJsx33RKwhiBo8SC59CWFUGZooA0+cMdR vNu9rd7rrS7qmCvnEQdggSSHIwuK8AvmhgC8LQZN7B2OAQEAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/content/vol21/issue10/images/small/ns1015209008.gif R0lGODdhXwDIAOcAAAAAALGxsa+vr62traurq6mpqaenp6WlpaOjo6GhoZ+fn52dnZubm5mZmZeX l5WVlZOTk5GRkY+Pj42NjYuLi4mJiYeHh4WFhYODg4GBgX9/f319fXt7e3l5eXV1dXNzc3FxcWtr a2VlZWNjY2FhYV1dXVdXV/7+/ktLS/z8/Pr6+vj4+Pb29vT09PLy8vDw8O7u7uzs7Dk5Oerq6ujo 6Obm5jMzM+Tk5OLi4uDg4N7e3tzc3CkpKdra2icnJ9jY2CUlJdbW1tTU1NLS0tDQ0B0dHc7OzszM zMrKysjIyMbGxsTExMLCwsDAwL6+vry8vLq6uri4uLa2trS0tLKysrCwsK6urqysrKqqqqioqKam pqSkpKKioqCgoJ6enpycnJqampiYmJaWlpSUlJKSkpCQkI6OjoyMjIqKioiIiIaGhoSEhIKCgoCA gH5+fnx8fHp6enZ2dnR0dHJycmxsbGpqamhoaFxcXFhYWFZWVv////39/fv7+/n5+ff390RERPX1 9fPz8/Hx8e/v7zw8PO3t7evr6+np6efn5+Xl5ePj4zAwMOHh4d/f393d3dvb29nZ2dfX19XV1dPT 09HR0c/Pz83NzcvLy8nJycfHx8XFxcPDw8HBwb+/v729vbu7u7m5ube3t7W1tbOzswAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAXwDIAEAI/wD16OET SaDBgwgTKlzIsKHDhxAX0nBQaJIUJpdUxGgQpFCMGB5BfvxYCAaMQScHqVzJsqXLFy8GxYypEqZN m4JgCtr5YqfPnz6NRIlokMAMokiTKl2oCFTSAUeXSp0KsYYogzUSdGGgg6EAGlTDQpyyIyIiKgiF eErhFYfYtwgvKUGIiIDDGQEMrtCSBQ6mgSz01PhhsEojqoqMTCJCZEglSQIPjUpYAKIlJggNXXFo CIvBHRmsEHDEcFTZqQf2IJyCSE+MzQgPQCTSBGEMAwZTJElEJMhhPTCyJB3Vg+oBtgdHJdIzqEpC LRCHeEIIQ7ZgKJRf4EY6peBULioQjv9ipOeFcITbHQaZftC8QERTEO7J4h6pFMgCN4EphFRLH4RS HOZCZbGp5lAkUiDkwhYC1ZDXQSkg8AJ0SzUwBBWJjJKFCxHNAEYBVoTilkEJCNBFH1lcMcMoXLQA kSaWONCEAP8JBAgDozgXgSaNKBAKXBH5IaQffPAxpB8qrKCkH0o2qWSNC/Uh5ZQqVFklH1ZeWWSR yAHp5ZdghinmmGSWaeaZaKbZEB9HaKImXDNAQMABl0ilgiBIvAkkDl90sVxCgHwhhCbWIaQCGIco 4sAJeio1Aw450GCIIS+4UGkLLgCyQh8tBOIHIC64IIhHgmBaiCGJ3IDIDIJ4ukKXQEL/ksEBg+jR yCUvgJKJKJVg8iNCoOQxAAwGIaIDI4oge0ghL7SAZAp73FmqpTBYKhMLLiDSCA6SMutCIIG8ymij 5JablAsz3JCIIYWoVG0LgAAiJKiZxgsIC0w2qWkfSx45pZh7lHVDD41UMggobHG5hyg2qDHJCgKx wIkGF3QxBSeYGGFEJDi8gK8hkjjCSA2IIJKIIjOwwK8hh8SA0keDtIqvH0A+8UMKDRhi7s4PXaEz z2/h8ERSVvwMdFg3/CrQCoZkwuFCA4B1dFiIXGXQJEwY4txCVdQwtUGY1HmQIQI4hIgVBqmQyRID lH2JInoc4QRyAuRgJhMJEmWJmwcd/zLAXWgLtMcjPyzxCUNU/CYVgwgFANYMsB2EwGyYjR35QjEQ OFAnDyxACUNkUWWAgQaN4nUhfyPEuENEsGdQIRQadIkHoYw7iGfcQULVFrDqMcoN5ZWNUOwNTTL0 QYNQWMNQENKXXkSheCfVAVAKNAV5LuB+0AHjNhQEdgcJch4ik0GIhSDEK6TIV1W0wAkaC2DAxSef PFG/GGd8AgoUUIDyCf9QsB//4lAFKEThgFFgwwKiYIUOhCIUB3xgHKYQBVCAooIVvGAFoQAGNoAi FBcMBQHkIAopJOANoZiCCqdQhQ9soQFnksALBBIIAaDhAB1IABEe0gcJLIQCNdrBBv820AAMDOsh h4DAm2BgBkawJRP6+QIatiAAMuDgAVZDyhIeAAdGeSFOoWhDJ9LwhE004BBfS6Ma0SSFMAxgcmuM oxx59gJIQAIKrVmKVdyQiTkypAZCwILXEsICI+DgaYBSwCFMRDo/GiQQQnhEJCCmEBcUohCAYIoQ JAE3R+LgEY9oxA1owCyZxIsPe4gWv1agAj+w4F6sVAELchKzQOBLBXzonhqNkIlLEEESkcgBImhQ gxoYogX8CkS8BDGIQ7BMVYMIxCFwwAgcJIIGNIgBDALRhz2cwJuODKdCINaHwBDFBY9AAiRyoIhV aRMk4fJDIHICExd0KhDOqhIL8KX/pFe2AF6aouTXWjADRMSgJ6XaJyz7cK955WsFTMKlLBWqqSNt KjxACgMZyifOMQWiEw4QghYO0MmOimkAMTBpQ3JwPKIYRaUMYQTziFI0mDIlb0QZgNFsepBE4DQi A0AjT+mC0xPcwAxIEAJDBpDHNfZhC5YwSxb14IgOREBpCaGC1L62giFQghKaOAIlKkGshiBCeAbx wwwZ0jU1XqKPB0FE6hiySIS8YAd8aItb+VYs7S1kBlvTww+QoIlBXOURnRBCJ2YghUIQAA7AC4sL hCAEFx2kB5OYhCXESoTIOqQSfBXIDOzSEM0YhAVzIIMR+LOQxFElfXqYwuPmahDY/yqkEkvIDGkZ YgjNBQIKS0iCQBMiiq5MJQu61EMAWmPa2EDECJ3IzHkYUgi/CiS5CKGC7qayhUbG1msx2K1BCtUQ SkT3IDGY7kJgoD1DTIAMkygpcR/xWu9OwWswCNz2IEKJlgoEBhTiw/8MuD8pUCJ7wynOVBCQ14ME wC35fQ5EJuG6/1qnBljVQwoKUB+ijEJ6S0EARkvnlhfQViDqZYjxEDKIC/9Uwxy2bUNEAWKliFg8 dhOEeAVCXoYE4XDhIxAiMpyCA0woKdF77YgFIgq7DSgh3HtIEGYqkAW9h6OCM8ALehwlg0ThEQGQ QiQi8YMfQOIKnICIFoarhwDpAf8QmjNIdx/yg6nqIRCMQ8SDDLKHLaDvIVLYwp/U1GCxIAc5/6HZ VFwUCCPMwLsOYZQK1mqQTAriByoAhBBegF2HsIUF3ctrDIAHgxywuUxlqJUe/NADR0xCB5QIwkP8 MIEfZvIEKegDH3Tthz6c4NepDPYeUkDsG5ThTX2wxBfspochgMERQ6CBC/jAG0EsRROai4EAWmkQ PiAyjXzAD5h0ANehmvvc6E63utcYBQQgIQ3rjre85x2mUSQADdaGqSWoUIXPLeUEkHBAuU0qCAiQ oayZ6cISAgBHhKRgDGmQQFRhugIrUGHJB+HEJxzwF4XMwAJmCIRNJ4KA6hmkBU7/eMRWE7KFLZAn nDBIRA50AIlEtEoQoYoXRfEVCBh4xBDabOYnQ5mDRDCLSHK8QQ6QpQhSWgqfrpQSPleALXB9q9d+ sOQMPlKtfWIcLjUAA30Cw4kLCGIUUtjBGhJ0AnsBIgxA8MASzDkDRdj9BodAqD0BwYdcD6lTLdiJ LflViFQlogbYPASrID21Gzyimo3IgapmcIhS9SEFrfwUPl2AkkIcYhAuoEHJlnVzeKmA8Tw7QRYU YIAoLMEIQ4jEDthJg2aFypaBNwTicaAIQ8DgEDXIAQ5UxS6Y9DqXnaa3OAPxAkZIXpuVmucgAMoC cFm9Ba8MVzlh6crqdwrriv6a/yBgUIMZmOQF+AyEPfGVfYCC614NhSgLlrSpIW3K5F76QRiqsIMK TKIKcERsxBYKhFAGPWAgLoAJBCAKm4AElUAJkvAIOJB3TFIIjOAIPxAJkLAteMcCe8ACM1ADiVAy NYADPfAIhwBLatQCLwADLoNz+MQC8IJ1+ySDTNIH3cdK8jd/r+RKTCIkp8YzLDAILoNP9+JPrxQv /7QvOQiEr/SEEMUvQoKDQTgVm/AHlqV8DKEDdkABc6CFSZEDaGQIKweGB8EIVvAJl7ADTEADBJAA WGAFAmAFVSAAdSgAeGiHVBAAAWCHfHiHd2iHVTCIAsBveDiIdWgFcqiIA2AFV//wiAPwiFcQiY44 iYpIAFdAAJq4iZqYiQTQBYThcVXQCSvQCVLQYAKAcOfGCBUGETqlbozgXxChIrBIZRDxUumGA+CT UztlboqQYQ/xiul2A7b4EDU1jHbWM1GBbj6VFFcgVOiGYc4IjedWNQcxBGRwBsloEFZQhl8jCWKA ACL3ENYoEDfAAFthXArBVHPkZhBBPnGlBqEwcQohAE21Rk7gWWazZxomAAnAWgqxXGp0BGCwBJug BAg5AHGmEGfVN2MgBvSYEG2VRpgwFwdRA2glEfoVEQKgj0eDBBZZLJejEHWVVmLAAfeIEFYwIl8j F3QxkgkBWAkhCLuYEALwcmP/cghgIAY4+RBtghA0AJMIIZM05AlM4AS6Q0GHgAVNkAl7EAha0JNi IgQdFxGWkFt9s2MJYQj6xQgU4AYNMBQ90AmBcABWoFS+w2xUAQMN8AXfVggV4Ame4ASd4AlQ8AAQ gVtDeWJb6VeCcAAPoIrZpZZLIQaacAlHcASXYAllkFIzsJE8lpdYaRDNxVua0wJegABc4I0G4Vqo kVWzxXJ5uQmZwZe2sVt7MAmUQAWQeRBToI5L8TwCIZCGwJcN1xCVUBtjY10JUQiaowMDUAOKkIUJ YRqiY1+t8RpQlpe6aRC34RDs9TosWRr0hRrI6RowyWUKQQTn5ZzpsQdIkAiT/wAJL+eb3eYCTfAA YqMQo1CdUqEF3mU62CmaD0EEslgIsokIImMQg7BbJ7AJYkAF4UdcpyEVWeBdAUBqtslfrYifCeEE yBNnijBIoOOeSwGf4rEcMMCX2pkQ/UUdF/YFZTailNAAgrCQD0EcxlFoAkEFcNMcy/kQQwBkBlEd DWKLfEAfKfYQU7Bdi9M7AfCiGRmZD6EWLLYdy+NwWoaiDjEFoSgVDJZdcPMCQ6oHO6oQM8piF0Zk HCabD0FjVHFjyVFiMHmlCSEEsqgdDfJiGzYIZgo6NZYUUZoc5PECMCljCLEeCCE+DRIfBzEfR2Yf cYoUB4Bxo+BkdwoR37On4//jp7mRBX8mqMZhclPgZCiKpwcRBE5xEC6wHfD4p0aGqQoRCrKmB33g BKKgYBHhHwghCocRCCgaZerxYi5AIWfhcFuwZUkRBZCgCKMQQFCgP6LQiwthACbnZrCaEAiAegcR CXZmZXpwqxAiIR1qECcgAAjQSZ3QCJ9AjYI1cAwBk08APClQpUyaEI6wqWmzHTCQjFmwAl6KEDdg BTUwACtwCUiACfqqr/iamP5qBJUAsABbCYxRCQ9IsIzxVUPgVUMgBJTAsJMwBJIwCZQlCZIQBEGQ gRibsWSWgXZkRztgR4/gCKB0gqDUCD2gag4BaVQwCUogBUowBd7aEDhQLfL/pQehMAoCMAVy4Qma UAXLWF4JwAlS0And0wcDMAVYEAWVEAWaAAWeUIUPcQIB8AKjMAVlUAksWlpJ0ARWEAAUqgdXMAhO wARTgHZkQATMijyCYAiUoDh6wAKjoAICwARRMApYoACcKSZGMGI0wwg78ANwyxBomRCYMC4uAAmP kAVMoAX51hB+sENmAgFrlQMTYAKfMAJSYJqGokQKUQY1ggkP4AAJsAAKMJm8hZdm0gViZwBZgIma GIlZMLtZYABaYAC2uwUHYABbsRDoqAXAC7y467q2a7sjxRcGcAAtFwa8aSaghF5jsrVAA5wQYwmi AAGYoABhYAVLoL0eCRGM/0AGXSAQTZAAE3AEX1AFPWBGVvB1aSIxmpBJfMAESJBOjjAFRGAITSCY EeECFmkEW1AAVZAFNEAGN5AJjmuGCrzADNzADvzAEBzBEgyGiaAFVjCzC/wEdQACRxDBPWAGCzCo EzzCJFzCJlwuAUAGkDVUNKCyS6EEgdVROnABEVAGpaoUFUABY2BTiiAKFkABj6sUgtAJmQRTQXAA B2ChfLYFaBOSB7ECUKADg6ZSUTABcBCRB5EnSwCMArFZDdCd69YCEWAGCkAaCcEHXNAEnxCvjgQK T8CACtECBaAIDbA6CMEFSbAEQulHhiAKBJABGCxYAvxtB3EFFGAFaaZSjP9AAgkgBAOaNhKQARUA rgKRAmSwBWwwBOGUa5vyKn/6a6D8a9aKJbiEJRDFStDSd8l3NDGAA1KsCHkneIHnLPSXdSgBA1vX LDFQA86nCDdgCNF0eau8M4hQTTdQftMny9i3Aq1CdaFiE84CCEQoesAcL+EyzDtzAzrQCNuCCKWU KSygAsRGdUNihPm0AizYgjBQKYAgzmcyA9DBCbWSCOZ0EIAQxILBCNvSdD0RM4DQAilwArvWB0ny KZ3idX0QCDGDfsq0AqgUJpJwBUoQClVwCBNQBqBAAHSgAlgAPDRQAAWABQKABwAAADxwHjPQCMeC LDPALA2dSitgEzBgCFv/53PcBAiOYAmU0AME8wg74Ag3UM9AkgibgHqSVhVFx8vW9HkuwCS5ZCRM olA9hxLgwjIHJTMNhUtxBAkYCwmR0AORMgPZJAgrsAfoDAjg8gIhgU0ngQg4gAPlZxIm4QIrgM3l 4gSj8ARJQAk/0APV1E6H4AJIiC1ESIa+HAOCEAM08NcGJRMvwEreZNdvsgOPUHQH9S2w9NCirAfA tiWolAKmrAIETWxre8KmrSfVN0wuA84y2AL3R86dzH7hnCTzJ9r8wk/iDNpqZEl2Jykn0SqYIi/7 pH4AJdz3goMPBVH/PH9SqEaBMGo1cNXfkimZ0k/E3doNhYPI3WvyN4X3/6dGgqAtEwh07cJ5rSIk xG2ERigvUgJL3f3PgNDcY9IGNxAETQAIvZIQm31yRjAKmCAEOwDLMyDWhkDXftACMw191+fQ6Ax1 aG1PMsMkY5IAV1ABSiACi0GahpAAXMAFB3AHJV0EMFQeGuADiyADKFACIdABa+AFnIAImjIJEmAG YIAABiAABDAA8pwCL2A4SWAJlXAJmvAEniAJRrgzJ4BxgIDLLiMT3wJ6/xTV8qJzt91rov2DrmRL QPgkK3gqB9UTymQvP6hzKpMvN5gkVAdQWN7dasQCnlctyvSEN3jgUDeFrqQkVULOQsKDT3JRaiTQ pQwt3yRskf1NjBLK4wgSyggh2UkREAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/portal_imgs/search_result.gif R0lGODdhOwBQAPfXAAAQc/b////29vb29vb27vb2///2/////+72/3t7e3tzc3tze3Nzc3Nze6y0 zay01bS0vbS0rLS0tLSsrLSstKysrKyspKystL20tN7V1dXVzdXV1dXNzdXNxdXN1c3V5s3V3s3N zc3Nxc3N1c3V7u7m5ubm7ubm5ubm9ubm3ube3ube5t7m7t7e3t7e1d7e7t7m9tXe5tXe7tXm7s3e 5sXe5s3e7vbu7u7u9u7u7u7u/+7u5ubu9ubu7ubu/7TF3rTF1azF1azF3rTF5nOcvXOcxXucxXuU vXOUvWqUvWKUvXuUxcW9vb29xb29vb29zb29tJyUi5SUi5SUlJSLi4uLi4OUvcXV5sXV3r3V5sXN 3r3N3r3N1b3N5sXN5pSszZSsxYuszZSs1TFzpDFqnDFqpClqnCBinClinP//9hg5gxgxgwgxgwg5 gwAxewAxgwA5g83Fxc3FvWqLtGqDtGqLvWKLtGKDtGKLvVKDrFKDtFqDtJyclJycnKS01aS0zZy0 zZy01ZysxZys1bS91ay91ay93qS91aS9zaS93py9zZy91UpKSlJKSkp7rEFzpEFzrEF7pAAgcwAp e4OcvYOcxYukxYukzYOkxYOkzb3F3sXFvcXFxQhSiwhKixBKiwBBiwhBi2piYmJiYmJaWqykrKyk pKyknIODg4ODi2J7rBhalBBalHNqampqYkpBQWpqaikgIHNqc1paYiBalKSkpGJ7tIuDg6yktGpi ahBSlMXFzZSkxYucxQApgwAge1pzrFJSUrS93qS03qScnHuLvc3FzRg5iwAYczlzpJS01cXV7pyU lMW9xUE5OXukxbTN5vbu9u7m7t7V3rS0xYN7e+729gAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAI/wAPCBxI sKDBgwgTKlzIsKHDhxAjGhQQZ1MIDidKxBHByUmLHComiJBI8iCBHTtyHEhzckeJAWnSDBhQsqbN mzhLCqiZY2fOgxmYVasVccCpKVMSkKL5k2CuHgc2QBwwyslAPieaEmxU4cCJCaYkTOAUdsAGnydU HjDFoOAGYkxCEBNYIcSBAZswqIW4KVapATluSTgRIRXNVkQPwOIkUFSVgk4WHFAxSiCqrqYo3CUZ J5aEA1EYc5IllVnlHKIgNEZVMESrDCdkCZzyuUUwqSUxMDoghcmBTQ023MBwiwKnUlMEQnFmgKAI Bi1iz/58QESwrAvTEDwx4kAIWAeoWP91kupAiT4nXjlxPXDULOycMCg4sKPygVumJh9gxhhiDldU VJGVFJ9x0ooFTMw1WA6oMHUAMaIooEA1HCgQAScKTBAHMVRAQcwEvpFUgk0zMeTgVDbY8MGKLLbY 4hUwWqOVQojc0QslleBYyRGW9Oijj2DMEQZCKszkE00DECDQAALkkMOJBGk3kCLLFDTDQh98gZAI GWQQBwdxhBBHCxpoEEIGLqiAEUJSCoTIFQLJcAAPQyzjhRdhBGCQFloedEIKM91ww0wE3JDWSznc 4JAiWQhkyBWHhPHFD5cYYYM1PBCU5UFpiODEBhxwcJELcrjggggitMBBB4t2EWcSjoT/EYgYiSBR SRdd4HAAAgVsOiNCiKyojCZ2JJEEJpUYcgkeNnjBQyGJdAHCkL8eFMQXdSSDhK1ifHGJEJg8kskh QhhSBAm+VltQIUfkgYQdRRjxhRiXGGJEMpn8UAcJYUBTSJ/VtnnAIVoc8ogZjogRiCFDyOuIHlfw 8MUVlfyrrkGHfAAEGXgQEYgShgjhRyCOOBKIF4b8wEMM1F480CFYsBBJEnl8gYm3fiARiSNJDIID CQfQ0LLLBxSyxQGW4JGEzZmE/EMSe/jgwyUwHPDB0C4fcjQOROiRSRGVJHKFH4ZE8oUhNgh0NdED GR1nHc/ImgilXdhBBsA0XMK2QG4T/yTEpImI8e4iaaut9959C7RFIJbIG8YeSRjBwkB571300QJZ Y4QRelwyiB92XCLnQDYcznbiB7BwhRF1uHtI1QTFYDrRhVRZEA+GiOHHQSbM7nIhwFgh/BHEC0+H LVYQT3wxVqhSieVBICO99ABMb/31ABgB/S+TdO/99+C/8cYv2u8NBPjooz9++WyfP4kv6au/vuVA cP8997/kr3/+3UvCPtH1mwQb1LCGAhrQgGpI4DGOsYY9aOIHPyBEIQghjAkW4oIYzGAGM9YQLrhh EnXAFA9wQMIS4sAaKByhNVAggw/IQAYviAEIYvhCFtjwhiwwgQ5NwAMWCKIhW2DDG/+I0JAnQGAX TaBGEyCAiyfs4gIQgMAFmoAAhiACiG14AxIcUgA9efEAegKjGBkSgCsyZAuhgMMWnZSDEkSjBCdI Sw4yIseUHKqNJYDjDfAIRziyUQVpOYAZF4KFUICiCAfoCCeYsIENMAEDF9kEJ6AgpjAtkhMt4IQm N6ECLnEgA5yIAxM04AJQboIDgmzIFT5xyANAMgQWUYGXqlVGVerCE4i8QQukcagSsNFJBMjIk4RJ kloypAar6AQR7+IkZs4EME+C5kyaKZEAKKIhNFiFLhAZnTnKMQcZkMYASrACJ53AUBmAY1qiI8cT tCAFGQEkdgQSCDYRhAa0YAUi4/D/JQ2IoBlMmEYoW9ACY2xgE1DQwEHFFAKChiAEKWiBCEAVgkZ2 qU31ZAgNzrAKRIogDhloQQY2wImJOsFTTCBoiGyyO42S4QxEFEAc05IRAvhypoeCkkRaupAYkAEN WzwAAQDzTKE+UwBFvckfGiKDMZABkSVIQQ54qYIVuJMT8TzBAD4CzngCsktxJCgcd7ABQIIzGqlk iAwiUQZEkrKRHGCCCCrKCYo2NKRn4kALXBAqVXHABaDKAEbKuoEdZEAlg1TIDCKRDEQ+kgPNKGhH 9qKVxCaEBY6ABCIn0844qiAHLfisCj6CE8sihAV5cMRmS3SXorJWpyQx7UFYsIc8/7jVnWUtQWjn GNEMTIOgISVodDYAXOKSUlQi5cCJZGsQFthhD4j85EM50MgQTOOvAw3VRVKQgRCooJGgckEJRtuC DaQlA8ttSA/sYAftFbS8XXpomAga1y7NNZRxUEFFT9AfKzaEB0iInECiswM63lQFN1CBbk8QzDm2 wJfwPIELdkDeiLpTBQRhrsB4YIQjbDYhPmmIlASGsf9WYglLMM9Iy6vXvTaSoCA1r0K/S92RYiRV D23BmFTloEM0BAeXqMTzNmAmNF3EAw/dwJkuEgLcnmADqQrTYVNwg5ScBDApIIiPOUUQHHhryHEB bwsq+hGMeIm4Is1xCDSASYdsefIhXv5C+bwZR2+aM5A5KURDrBGIQDyvtdZ4pqCTGoACdLHQhk60 ohedaAQAYs9+8MMckFWJXgjZ0r3AtKUtUQleOOAPf/g0qEdN6lIfohAPKMQf9GwiQ7g60n4YRqRl nYhh2HoYiUiEH67A6EQH4NfADnYYpwLBHwwBgkMYAjS6MARcNRtXzIZdwAhSAGhb+9rX9kIXYCAH 8woXkO9U1E8CAKNym3sZVyCButdNgogxpUQ+CfFPZJAiG5Cg3i/Mt75fmCnLwWDfL4SBwAdOcBjo wHJzQgHBFc6Dhjv84TwoAMJNOEIS6gABGM+4xiX+q4AEBAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/stemcells.gif R0lGODlhwgEQAMQAAG2KxRFAcKe52czW6LfF2lR2ulBzloqiuf7+/mOCoS1Xq9ff6wg5nBdGouTp 8MTQ4DtisYqh0H2XsXaRreDm7i1XgTxjipSpv5es1e3x9nGNqn2Xy52x2KCzxgAzmQAzZiH5BAAA AAAALAAAAADCARAAQAX/4OeJ5GiW6Kmm7Oq28CvH9GzX+K3n/O73wJ8wSBwai8ijUIIgMEQJAakg MAUIi4ZIsjCcBAsZAfB5bg4mw4MEyUCScGV8Lq/T7/Y8fq/vBy9SHgEKdBcEKQdafot8jYyPjpGQ k5KViwNPHh0bUIcjBQQjDQlkBQgFH6AqFRkDhCMMFwxjH1oRFyMKBgMiFageaJbClMTDxsXIx8o/ EAQDDr90CQ8DA60Tmcvaydzb3t3g33gWCAJPDRMFFw8GAAYFDxAShAQVX/YkGxQyDxHtHxw6mEiw IMAICB0UTAjHUFzDhw4jQlxEYI2HKFMENLDAwMIGCws+AKhw5oSpaCrG/wR4U1KEGhQbMkyUSHOm zZo4b+rMyXOnz55Af3oQGrQo0aNGk95UQABCAAAS9DDoIMBCg5UXKBhUyhWp165gi2FYkA1AggLv EkCwgLaAQXwmKijqlQEuCQW+3hlo8G4rhL1sJpD5Sjis4cKIY2howmBrAYFlDAQSQQEDGwRvTHQI +YJAAhMSIkx5YEKD6MSoD6tOTXixhk+QPRhYcIDDIAkCopK8MFjEhQxbVxAgEGFh6NEnNpxazZx1 8+fFMosknSq25CkLH5TUYPnEs7kHr3zecjoV9S/Q0ztfr/6OgzG1t254oCjBgAQbDGyQ0BiDQQsD 2OVBBWDkFsEA/hHQAR4AiVxwX34FLGDWBqbh1x57GF6oYYYcbuhhhyCSEAIAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/search/homelink.gif R0lGODlhMQAQAJECAAAAANYTNP///wAAACH5BAEAAAIALAAAAAAxABAAQAJQlI+py80BwwG0AkPn FbZj64TiSJbmiaYOlGTfC1fa5jYsUrs5TcebCgwKh0SgpPXbyWCaD0gRwSV5TY7sWXvcmLrp60pd KXYzstS5LKrXqAIAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://cancerres.aacrjournals.org/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAAADEpKd7NzTF7pAgIIBgpUqy9vf///wgxQWqctAgYMSl7tCBag3ucrNW9 vZyLi4uDg7SsrDE5Oc3V1e7e3t69tBAYKRg5YqS9xTkxMaSkpAgQGM3FxSlaQaSclKS0vUpBOYuk rJzN7hggSouktEqUtIO0vaSknAgQELTFzUGUvQgYKXuctEpBQUqkzaS0xYOctCBai73FxYucrJSs vWpqaimDpAgYOZTN5ikxMVpaWs29vd7m5loxKZTF5s3VzZS0xXNzc0FBQRgYGMXNzZSLi2piYiAg ICAgKVqkzYODg1pKSmpqc2qkvSAYGKScnLTN1YvF5hA5OSliOUGUzRAQECBqiylqpM3FzVpaYrTF 1YO93iBqQZSUlAgQKXtzcyBqlKyspCkpKcXN1e727qSkrHu03hgYOTmcxUE5OYN7eykgIL29vWqs 1eb2/97m3s2srGqs3ouLi9Xm5ubu5hAQGEqczb29xYO95ikpMaysrMXFxYODi0pKSjk5Ofb/9rS9 vVqk1dXNzZycnGJiYnu93jk5QUFBSkqc1TExMd7V1XO93pysrGq01d7VzSCDpN7V3hBzQTmUxTkx OXuLnDExOTmLvc3NzUpKUpSkrCApKay9xc3NxVJKOb3FzXt7e1JKSmpSWmKs1UFKSnO01QgIEEGc zSBiixhBc4usvWKDnNXV1RgpWsXFzYOktDlBOc3N1dXVzbS0tHu95rS0vTmUzTGUxQgICBAgObSc lGq03gAACObe3sW9vd7Fxebe1e7m5qy0vQgIKVJSUmKs3u7m3ntqat7e3ggACO7m7tXV3vbu7vbe 3lKkzVKczc3V3imLvSmLxVqs1TE5Qfbu5t7e1dXe3qTV7t7e5nO03lKk1QggMUp7nObNxebm3u7u 7v/27kqk1fb27gAICO7u5ube5ubu7mJBOe7u9r20tObm5r2srPb29jGLxTGLvd7m7mopKfbu9jGL zaykpDGUzebV1SmUxe729qSDe73V5v//9vb//6yUi//29vbm5mqLpCwAAAAAOwBQAAAI/gDbCRxI UCC0ZgcSKlzIsKHDhxALSmx3EKLFixgVTixYMaPHjwk3EoSmDaRJjCIHRivZkA0hHUpOgkxpkOVC PYn0HNuTUN1CYAt9Hvj2TSG7jAIl2Vpqi4okSaaotLOpME0XoxCC6PhmhBAhUOwugdKxR4+xILLS gQLVC2W0bHgKbRGlK1A2ETgkIVy4LACbhRy6rNnT58mBNLL6DDqgLsCgLoUTHUPaLo6ZbKREiSqk 1Fa0vQv7BFG4B9SlNDKGte0zL8MlxmK6RNgzaJhHgUl0NcomTfPAjgsvJQqiZ96TNHqcsOmT7oAQ WZ9AyVpFKMieS4NA3W7XqJAZPLxd/kQzCDpol08R2HWRpVOWTz0+NXxapV7JpWOybkcTtaiQNl1z baELRVTJZGBI7aChjTSmNGiKC6YQ2BA7RB3IEBtHOaTSeCoJtFJDn6QxzFYWDpWIUA3R1M6HDBHy yQGJRHAAG3ocdUmNB6ST3wF7lMHLAZeswhONq/ghSxiTMaQiSQ11xcYkq8gRRBFBXJKBBup8oYYS n7AzyCdCHOMHKHJ8MowcrSTyxRd+FLXQkuUlVIMfibw4nBItcODHIOqI8YkaoHzzhBqJ7OHHJX1O 9k0G6rAjmZI0AacQIUo8qc6e6gB1aReVwPcNBIQcU6gfx5gjhiBD+aHON6RCmpKk/nKqcUALXejR ghqDXAJBH2xApoQeGgihRCK9CLHKARC08AUbQqyaRpIaRRonYz6p49MxbDS6x7EHCFnUJd8cww60 3iYJbbSvFliiSQS5MxGL68o0kCRQ8JEFJTSYUMKKNhHl778AByzwwERR82ZSbhgDTycdTGEDPfB+ o8/EFFdsccUJXawxxQe3Ywk/ocCzBBeRPCIPkwlJbHE/G0/8DTDHVCNOyyt3LMkD5/TQyRQdPAyc yvqwzLFC+rx8zDHqiPONN+Tw0ijGHOtzgNToSkJLziB08MoA9Py8MYXkVIP0N6smpPQB7KxyjDIz azy1ze/wg08uJ3iwr9f95M3O/jLkIK3OMj+aTQ47wFTzg8TqkEGE2m4GPfHb6LZjBgsJNFG5ChSB JnE/4njjDTDkoKjOH+KQs4oiwHxDhjp903eAOaV7zo7FHdtiRzjhSLOgJBImtEzKjdOhzzJ0/MC6 0r+jXVQ/iqhDxxtHhQuMN/dMTTWCAmVTCDGFdM97xBMvQwba6sTifOdU8/3HN9XEMrtP4sQic4Xg eDN1Pza3sUUb2mcTYcQsI0fzVAeUhJCjH8sAhiJW8Q12sIN16uAWMJYRrmOwDBgTA0fH7ECMuhAj G9kQRe+Ggr8KTQ0YnDPd55ZBDXEkhB3kmNoqrOWNo6yODt6ohtSudwCCRIOD/ojQhi1qopBlSO0b v1vdDgTwDXG84XF841v7xNEPoKRtfkURR+D+0DGRAMeI+vCHIngBDGDwAn+MoRAwVsFAdiTDAERQ xyWOkro16vAAQEFj5OjBxz4O0Wv6IIfByLc+dQiijAlsoDWIQAMM8KAa6vDGMbi4jGLQgRfnitwp GMDJGJxiAbb4YviWQTpvIKqJ1aAA/jaBDXa0IhjcoIE56IA2xiHxAMtQRNAgFcoVEEAYXtiGBa7Q NdAsg2X+mCFRfFIMwNVjGRTIxR5k8IEUNIAXivjBUVa1jNOxox/qyBsvoXEDAgQTF2e4QihtcsxA ugmcB+CFKddxCQcwox8v/ggBDVgAum/QQYEu/AYZjybOg4XyBsJAgBRGMAJiwqudFNTHAzlxjAb2 gxcp2AEc1vECGKiCBhNIYTUEUdEKjQty0TqoF3CBgAKwwqHslNoyBEFGcXTOG2Sz1jF4IYh0sOAF wIgFI4gQQ7TtRBH4C2eK2hFKBazAAmdgxUu7FtOJmZEcL1PH0Y5xwH4I9AMzgENR7nGPY8SCcewA hzreoAgNMTUaF0DABS6AClSAUpSP04c4FHGM8eFxFZc4ZD/24QsOAIKvdLDpMiJJjtAdo4BcRBcV tKGNcFBWG3bIXBEpxrKE/MF0qxgc2nixCl5AkhpmLAcSzVgNYIADfzxE/pcpuqOLOGSjDS7QbMry 5jjHmY0HmCSjOuQ5wcVCohpIlJrQeLvUWkClDbUVhTOe8hmFfCNvvBXn9cLljWXEo5Kx4MUyvpmx +72toAfTBgjxIAoQak8UAKTY7GZHNXH2gxyp6yx2hebbHeoxpY1Qb10aoQv/gY+zys0rdom2jOSx DH+83WVnXTXEZohCG4FgykNrVt7zejWSPF3VDoMWYesdILLYE4gtnjJED1V1l7Gl0HAx+U3C3XcV rr2f0BbCwyX1i79UoxAOd8CLb4IjhkVLkjeo4Q3xfvNxB8AfinsorSJiF4bWqkaGBPC7KlajG5i8 BC8EKjV18JUaeY0t/pVfpTn8AW68+kDRY4e702LkTR2BPCQMqajApA0tcu3oDIt1O5Qjumlcq5Mj MGZ25ChToxoJYaAhfQKOFloLyoCWRvdmgYc2EPq6Q6ED2Y7xAzKwoxu/qAAFDkANpGGDF7EoxjeI IDWYNbmA4YytD+PQPduKEGW4TAgZKvo+sx2DAvL8RTXAETRy6IMagm2nNwSL56W2oxYg1MUipBHC aPyshMvrR0WthWMqgsOIld6DOOYggwmsEc+Ee+Aq1LwiTUeBvdnYDTFE0QxpWJdlZAsdL8AVD8YI TYC8qIA32LAJT/wjBewoxzGaLJRyoBdBVLCDKT5IClLoQhr5uMYs/v7t1Wq0EJ4JeWw5eMFy7AJD C8cIBiCw4Q9rgFPPuXZVO+wgDV1cZi6e0dzUKBjlcX2DBzwQBDVYVjqA82IC6PCEOIAhCE8EbdHq cAS9B9KMQugCurzxtuZcxrRIxkIcdNzhuyugCCIsspoH8IfTyJgQFFpbIIFoQxvoEghCH9OrijDi AWiZckXUI1OKeMM3FgmEBughExNYxswUSI7Fbn1DPLdDZvHaYIXIjA5a5cAZo1wORwAiFptgAQ9g EII9wHvpEZRyFzfyxYRQgxzisNZ93LSMYwSWFzP7BizuoAoSeOIZWeVFMRLCA9kDekVMbfGGo3yf 38UZsM2b3UWr/sELIpCABK4YQyp4oDQzO82JO+ziD0UhjX2LwhTAltj9lna0Rt33GG/IlDqKEVyi PCMFgAU9U0MOgeVWAuEdIBQIukAMUdAMxnQxDwRBl1R/r0U4bBAk82ZANMU034Q/+3Aw0aALhVAL IjAH2oAHmicCMQVkE9MP3jBDLAM4gnAJMmMNPPAMvzBDq+JCErZ10eAD2sA/UdBBGXYNgbBZsKVm gIMFwHdiayRJ1qA6f5B+j4NGU+Yh70UXIEQXOOACSNiCaIRpVeQNw1UOlReGb0NiHZYh2GMH/kEP tUAFpoAH1yAJ7MRckBM1RceGVQhkE/Y4VzgQHLRvcbAF2SAJ/tWVMuwgDuCAdg4keeIAiXsjDqSD duAADg4UiYq1DJeoiX/gVynGVKageYhIaGjjQKiYiqq4ig60D6y4irPnISOhLvHiEX10i7hoD/5W iydhBVYABmDgi8IojKfADbTABrSQjLKQjMzYjM74jNAYjc2IDMiwC7tQjdRojdlYjda4C6WQCEiA BHVwC7cAANYIAABwC6VgjrtwC+OQjuQ4BOiIjlUgj/NYBbfQjdZ4C5UwDdOQA68gAYYgARLwComQ A4ZQB964C5hQBlmACYmQCISACX1wCH0gBDkwDKPQB32gA5ggBEKACZigA0xQA1lAkkpACDXABJRS Cd5YCjB5YQsosAEbUAc2aQF1UAU5WY8wuQtH0AcT6Qd+MARiIAZHgARGSZRigJRLqQmVcARDkAiG 4AeVUJSVIJSGkAeVMATjAJNe+ZUxCZbqGJPkWJb5qI/tiJa7MA5nqZZqOZZeGRAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/canres.gif R0lGODlhwgEQAMQAAHV1yEREtLq64+7u+DAwrBAQn5mZ1t7e8mVlwSAgps7O66qq3VVVu4mJ0Ftb vWdnwv///wAAmQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5BAAA AAAALAAAAADCARAAQAX/YCSOY4IAAEGubOu+cJsEdJDEeK67ibr/wKBwSCwaj8ikcvlLQG4wgKAV gESkq2oEEnBVBeCw4DDYdldYA2RtKETG4jAkNRg0bhBFXKCAPKwtXFpXUy5YK1xMiouMjY6PkJE6 BgcvBD6EEAMLAQRTCA0EC5ptJAmUeQBuIwgCpJgCAQZlI4ckCgAipwepIwVqBwwjAQsDEAvCJAzF EAIIb5cCooWtpGdSopoLmJLd3t/g4eJHBQoDADcFCOY+BJs+CAeuhFmAswhuCQ0DKuUKZwgGGBCR CE0hEQD4iUAwJ18xFeciJDiQ656IAAoUuPGXLAAYQYAiuNsmgsGBgbZG/xQcx7Kly5cwkbgTACVC gQYQnsWkJ0KdwJ21DgIdSrSoUW8EIKyCAWapyDVXVkZQMLCKzp5grmgkkVRFMxYpnxIoMOCqiAUL zIgwgCCAQl8UrwyoaZMXjTki+DhlwAUAhGQiGlQ6Sriw4cMxEjolAYABgwGLo/IcZkVBgxcQuIm4 pNZgTzu10q4oEMCpAAMCcq2YUUDqZpAllRoSSvAM4tu4cxedoTlL7xysvfweEjwL3c22WRBIDqOT 7ufQowP1BEFenwPMX/pdsyYi0bDSw4sffyTBTxYMAWunnfT4evLw48vPURZHOYo01Ki5cgA/A70L QWAAAwHEs1UElACQX/9OBMmjHnipiSQQgQa6YcA/fqkQUAM0JDTQWnZ0KBBIJ42lAH6yMAgAGQoS 89Z8MMYI3SAwtMcCTvytEE8EC3xIAmlkZWdAWn+BdZBPU4DnBAEnkbCAaiQEFEF9K/B1lxs2rnDJ iqs9IeOXYB4WVxS0XWRFWFq4RhkKbLbZGWOFmEMCGG222YU6ZCRlQJ1sOhASInchVGZQLKgZ5qGI tuRPZLPccMBlPxozmZkRBKTZir8ooOUAXahpi1W6FEkCajRKERBd5VSk6QquBCpCk5GiUKahidZq azcFrMidHU5lswZ+Z9JWKi9rSOOLGr9C6SltlKxiEncLQOFOsask1F0cA0v9Yowm2MI2gq+aqAYe rbeWa+656Karrq0hAAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.pnas.org/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAQGHsxGNVSKd5iIHM5IMWDWko5Kf///zkpGItqUs1aKVoxICApIP9zKQhS IGpKOaS9rLRzStXFtLRaIMVKKYNaSjkYGClqQcWce2IpGJw5IIusnBAgGJxBIJxKIINBIKRaMcV7 Uos5ILRBKVIpGPZqICBiOWopGEopGCBiMaQ5ICkgGIsxIFKDYqQpIJxqStXm3qw5IGo5IN5aKcWU c4sxGO5zKXMpILRqQTlaQQAYGDk5MaxKIEopIEFBOQgYGN5SKe5aKaxBKb1KKc1KKXsgGGoxIDEY GBhBKc05KSlqSpS9pM1KIOZSIHNBIM1aOSAgIL0xIHuki3MpGL0xKTkYILTNvRhiMVopGO5qKVIp IN5KIItBIHMgGDEgGOZKKYM5IL1BKbRKIIMxIJQxIBAYGBhqOb1KICkYGMWLaiAYGHsgIItaQUFz UhgYGOZSMdVKKYN7auZaKcVaMVogGGogGJw5Kc1zSjkxIO5iKcVaIKxBIHspGO727s1KMZSUg0og GABBEJwxIBhaKUEgGDkgGGIpIMVKMbQ5IMVBKVo5KQAYIPaDMWopINVBKaRSMe729tVKMe7u5mIg GNVqKQhaKdU5KcU5KXspIHs5IFIgGN5KMbRiOaTFtL05IKRBIHNKOc1BKWpaSrQxICkgINVBMSkY IM1BIJwpIIMpGJQpIJQpGPZ7Kaw5KUFqShAYIKQxIGogIKwxIN7u5jEgIJQxKXMpKawpIFIxIN5i KaRzWospIL1BOYspGL1BIEEgIM05MbQxKRBSIFogIN5SMaQpKSAYIP9zMaQ5KbRBMb05KZQ5ICBi QQgYIMVBMTkgIJQpKcXVzc1iKRgYIIMpINVSMXMgIM1BMVIgIGKUc/9qKawxKUogIDEYIIspKc1S KVpBOZwpKZQgGLQ5KWIgIHsxIMU5MaQxKZxaQYMgGPZiKRApIPZaKd5BMUoxIHMxIItKMUEYGP// 9vb/9pwxKZSsnL1SKfb27ikpIIsxKaxSKc2ki2IxIO5SKcUxKQA5CCwAAAAAOwBQAAAI/gAPCBxI sKDBgwgTKlzIsKHDhxAjSjxwb97Eg/PqtdjQaQOEAzCySSHYZ8PGPgM/EoQEAYKUkQPvVZw3696B effkxbzXhyfBWQ7qHZjVpsUBK/9gCpzFDMbAWcKcDswWTWA2qfIgoZwnyeY8i18P9JRpk+AgldEC OW3hoBNBpUcHZRsIg9lTqRfNqoQRyAokK1Ic4N1AsFO9QRZBOrCSN+FZgZ0czOrjtoUJSAJVgowG qe3AFoGkoGxccFC9ezAuEKYsdpDRA0tSYm7xmmK2QMI0kz4wSAqEDVXFulU8UuW8jSaFjRYIo8U/ xrt56x46/ACEQJ2GW/ELCer0A0Wj/ksvOEvowMBzD0jBbLXN0cQHTIofFJtgyIJtLoBMLzCa5I5T udXHgAQWaOCBA8IgRSBKWDFZH80JU8+DELYQTRsmWDHgLBsE0gYEKUgRTT0bDDjIBReYYIISKZpw AYYopoiiizOaIIwwDjigYooO4OgiixcMMkiPwqQoTCA5CtmjAykOEsggKppgxotCmlFllFC2OMgV UJphwhVcWlmJGWaAWSaXV6AIZo46fqlEmcwoEYgOOnAABQd44oOAEeUs08EyXGSSgRFgiIBPnQgU WugnHvDjhAfwGMAAAzn4sMMDEXDyAS64vAOGBx504AEnnOAQQQQh3DEJOfHEY4ox/qbEQ0c6VFyS BBXKJHFJMLdQoQo21qCyDSytBCPLJeEocwkFeYxBACkLPOKENLCowmoRoRAxxDefyKBLAbpwIk0B XaCCShGaaEJHHaiE4ogjoVxCRDDbUOHIJf5QEcwltvJbKyy7bCPICNJw8g4PHYDyjCa7YBIPLQiU c0MHGeSw3Yg+1GPMLsG4sEbAysARhiMzfENGDIgQUY0jcGxya8ejWJKEP474EYYvInfAAwVhCOKB DEbE44Ya4OAxyS5kfCICGE6gAwoCFTRjQRG7oKKKKoIgQkEQ+xQgzRNZMJLGIXYk84Q9h9gjjTS8 mH1HCCFk8Q0ld1CSRRB37IND/iYdiCGNGN/k8sQcT1CizxAjkDECndNYEAs125TiCDtb0CBKAhjs o0saGJTzwj4YFIABBpynkUYEpGMwbuYF3EED6a+nETvsptMQwhebbDLND4t0UwU35GCDDTeFiOKD KLq8sEMCISQCwgsv6KILDjiEEAEOnNzBSQSHzBGB9kOEYOr1OKDzvC4VJM/GI+gEQ8U2hFTxCjmo uGC1IJgYgoUahHBhhBegQMcISgAHODDhFKFIhCcQwUBZJGIOcHCEJ2QxCl7Z6hbpqB8qxJGOLhQh g6pwQTG2EYxmGGMa04hF/YIRBSrYaxzGMIYW+PG2HoBBGlloACu0oY4eBiEI/nBg4DgSEQZlbOIN QZDDG+CQiE20rB9BAAIcIgEHAShxE6FYBDaGMY0jdKFqwgpFtV4BgGZMwwk9mMYCwGAIT5XDEEbg 0wwa0IASlCALNmCEAuwxBArMwI55CGQespCFPMhhBnn4xgwUMINXcEN4u9jF1cIhi3NgYxpQ0AIB +MGPHtDiHe8oBCEKgQtAKMIdxsDFI+ZACT3oYQLwWAABMtEDQ3CBC+8wghZwQYpf8IMLYOBBI34B BTy8YxJeoEYprnErZZSiFJdQxSW+IIcgqIMdbwDCEIzwjB44QQYyeAEbEvACA1QAHDn4Qz3akIMH rKACEkiDAXSBBw7gQ086/vsEJrjxjGd4AAQduAE9IqHEdoQiCfdSRjDGwdAwEAEO7FCHHL5xBBLI gA0yUAQoprGDOKhTFCAVxTTmWQEDgAIf0+hBOQAHByJc4xLKGIco/uCOwwliCECIRCJ2SgRl7HQc 5hoHv0LxDRDgQHvwAEQhnqGFD+iDB/qYQAewoAUeUMJuWfiEKUiBhTe8IREuVIYqIgkOUbxiF4mI QRFDoQxZoAIWVrNa1c4RinHcABCPwIE01KYAadiAFYwIrGBZQVgbGLIE7NDCIrhxCUxYzQXBQAU1 VAEEZbAgFtvYRCQi8QWvwvQSVsOEKmLRBRaQARMg26kvKECBb9hDAd84/oMKNEDbAIyhFeOABRnG gYxm/IIcvxhGHXYBi506QqiX2MY5LuGIUsisHZa4BBVQMYxmLMIYmlAFvYS1Daupgh6oiKQgBDFa alijC9TYBTU6SAds3AATk0gXIPigCp/y7BwLdUTuShGMySahHUmQBSF2sIP5QcNcLnDBNhYc3qtp gAXUaEQqqIFa8vaiCPF9RjcAMQk6TOLDku0GGX4BiFRM4QTUYChoyWEMbmCCGqZ4BS16AN50pIK4 uyCHKchRjLdSgwUqIAM1yKCBMIyAX8YqAiC2+gs6aKLJqqBGFTBxjmecMBON6IIgEhEJIIRimK9o RpgbcQlqcJhqqCBH/hfrQA0X8MsRbwDYJcYRBgEEIZuJ2MUvUGgMWpjCFKSdBjl2sYbfcuO2yvDD JmIaimCQoxHc6IZjrWGNInQBFueQxTZC6AJlmOscyGBBD3BBBHUkkgtj+IQQboCNQoj5GRa4gTdM 0YxYWGOs5yDuNpyRCHgxNAmYwAUUsBGMnlFYELDYhryIkAgBfGMMysDGL5zwB11oQn8osO4rfEcI WsTwFdMwRQ+0AAVu/CIfwQhGHerwxe+ay5nj4AYtYJHcLtwgDKglIQvGKwgWJEIb5aAFPJInPUXQ ghSN2MWH60AH8y5iEa8gABd6QAqEn8MRwzjvLvgwjTLsQhlUaOac/gEWg3JgIhEUwGMe+tEPdjQg Dz1wwwIesI99xMEdNxiFLARxg190QRWNMAYpqlCFHiwAF04ggAbgAARydAMNk6gDGkzBsX1dAxhs FQQqzoEJOWRBDnkALCuyoAAu0AIAPmiDFOoRhwx8QwO7WAYFVEEHa02DFDcYriEI4IRHgOATiTuX q+aHCvoulwotVcY1WrYJdgRBDIYwRCf5gQUAAIAB9cjGEqzwBxFs4hyKT+A21MuNV5CBHtTQAjw0 5YQFaMEU6UhHEYpAjja7QBXDcsQIePCJTQShH6HIBzfwwU584AEP6HgGFKAQBxhswArRwMcuQnGN SPArEfSihjGw/jEGe+jhETZAGA/A8I5hkMMa6Yj6gtNdCmVoIIfqGMENnoFJfPjAFS0QhQFGlwYE 4OEPAPgHtMAHVBAKkWCAkbAJ7SAIZMACYZAFc9ABY5A7RLAHFNAMYjYN8QA57nMJm+AIAjAG76AF mIQH7sABAOAGPmAFMBAHmaMLaAQA04YCzzAFtnJEXlUKm3ANyhIKAlAOR3ADyjACYaACLBBDFhAP gIANu3ALwYBQobAMmUAKi8AA+AAOBmAAUPAABhAHcfAAYKAPeiANlCANPIAFfkYOsdAKmkUMSLRM 43ANuQMHWvAK7zAOJzMCrTAscrULkJUEOjhIBGBdzcAABtAD/giAALSABmpQDg3ACDrECKxQAobQ Dd2gSedQCl71BdgXDKrAB4KgAkVkCK9gDD0AeFUnSZJkNcq2CXlgA0NgB9xQRqRAC7QABmKQi1kw icTARInwBrFgBKUQBAowfQKQCKHQY+oVdSpQV8NgDM0ALUbQBRkEC5GlipAVCl8QBHXkWmIQD1Ww B3RURyUwByyADLCwByPAAs9ABnZABmH4DSNAXqigDOdAd4TADcOABX/2DI/kAbKQCpNQBJB1C6og LCFXCu3giiWgQ4FUAjPAMwBTCwrQi6HgCcNDBsjgbK1AYUVQB5pQC7WADcbwCq9wBI8zDJGECSrQ CNRwBNMw/gwq9D7pdgnX4Ai3MgrIoGoaUA7lUANkAAthAAR5sAnJtQZsRl7qtQuCEANk8AyvgA+v 8Ayx8GeEMJABsw3jAAQx9nCLMA2FoEzmkCtUwIOJgAjLMAY8IABAQAwzcEgC4FKlsHPEpQovpgEj YA+UoABY8Aqk0AHIMA6xYAzP8AuaMFyQNQ4jIGYQFwuYJgvAcA03+UyhsAmlEApAMAMCEAZ7IAR7 MAZkgIzE4Ag9BTAHqQGPMAFOwCmZEAZkMAbDYAq/gA3pQgfWUDUjQAQQ9gtqgAr6oi+A+EyW9Wg3 0AqJQITI+AZ5YA8jQA/QZEShcAvbcAO0wHZI8Aq/0A+w/jAJaEALz0AL3eCdtAAIsbBuZKBTqNAM VLcv0mUrpZAEykAGWPAM79AI75ABWvALWqAIorADxnADsKAM20AN0lYITlABAFgIWvAO92gNa0AO mHADkUYKmvBi4RWgqECYkJMEt3IJMnMJofBMiQAHPPMJ70AKF1UAD4AC3IBs8WUIy7AH9jAA0qAP y/AOhJCPv6CPghAGedYIRUANs1cu9IANZaAKvqIJ5hYOu0IFt1A/Qtlrm9APYUAL3WYE+6YCw6AJ yqBfXvVDPUQEYqAC+2SLFbejWzQ8reJkmmAK2DAJ3QAAkvYrwzAJXUAHNxBhmCACZPCaFWcMiVAK X3AN/txACMGgeDEFC+PwDUUYBrYyCi6QLSNwDtRgC9jQCFiABZmACpVEDXSACWRAaJf0Ctiwh5jw C0egVBxGB8agVF6wC7JgLJhwBEVwNWNVBL0gCCTkArvQBdhAdBXHhKpwDkQkAAoAU+OQBJGFaamQ ClApCAjVDo6wDSwwTJpAAr9AAnTgBb/wXvuEBnQACJrQBZPAB11QB7MXC6xSkg9nXdhVB1XQT6Yw RIkAC7pCBdVSBH82VumlCtYYDNZ4DvQgBK3AjiVpDIVwBIUwDV5ACDHZCKhlDZqwZNNAiMbwle3V TygUScqwC3ZFDbKgChbwCgyTXgpXnra2BtaQXiyg/qgjsJPLsAyfYAd2IALloAWk0GfPUHvkwE+v 4JVTWQhVYAzdEFxFMF670A3GYCymUAf0gl/DErJWc48DOlbqxQdTAKqCkFuwoAKwIAj0oAo30AiN EDyPRGsP9wxR92GxYEKqEAqtIAim0A1Jyw21si/boGnnICwLFQyRlGzjIAhTMFnnQF5dMLEd9qYy SQ7DMAzvdQPDwE9Zi1qpIGYeq1CCcAST8AvJ9KEKCQfQ1Fzt8AWlAAyRAC/bIKBspQytgDVBqV7U sG50wA3c0AVdsLK4Rw2kMA03gArTgLC1Ggz+wJQMuAwqcA5ChYy7ArCwoGmKh0XJVQvbEArKGZcU /pAIyqAMDCQIvcBwfJAO9BVC1KADi4AJwVAFRbsMMTAO8XkCY7AHuaAPYKAzYqAAQ6AAYUANgxtf wqMJQ3tCz7AJ2tAA6lAC2sAIIVAA2KMLfqcPIMAJ4YIO+ocGN3Co1EAIn2APPOOt2HAwnIAO4tI3 Q6ABmmClHfYLbtCdtOBqvlUOPFC/ubA2eERYWRDDgvMNQoAL/JAPdTCsoUAHbvAId7AM9YV951AI PeAOohAHuNAINzBo1BBcxEUGyzANi7C76wAF96QIo/YABQAKTTUHuWADx8AKx3AMM2AIPVALyLAL KpAI1LAI+BAH6PBbsoAJ5EAHw0AAKBAHErAD/q2QZtAQn6rQCmGAWFgABT1QBsjzAglgPCBFTtBT AaBQAQlAyRUAUtQDArmpAr8KCFoAlYvwKsbAAnuQCA1ACaAABYaQW2RABF7XkNowAg/wAqssCEHg CdbwA9OACRRwCk1QAqZGAWSgCW5geZbHDdSACHuQBypAhOG1C9W1BtTwDPkgBzFAAdqwDF5gBFPw DoZwQ5RgD5lAAIrgx3FQRn1CC9PwC3cgDY8AD/H8AA9AAJGyA/b3AATGA6FgDzNQQAkUCtvwC9RA Ba2ADbVwREBgBx0ABuXQAR1ACUZAAmjwADSQAHhQAXhgDL8wBWKwjigAChMgLeBgKUWjCAS2/g4P wAn2oA8yQATEEAbsy2WRoAzUMAzFNQK/wAJnIAYvvAwioA/6QAkyQAI7UAEV8ACFwCy5MANE0FOq UA6FcANvoAEWgAZlgAZegAbqImGosAouMAIrBQQ6uGjFlQjIMEBAoJ+fQFtGVrAqoEtqEAdpsAAo YAhMR4R11WnjgAcPQARv0AgxRgogVQHiVMnQ83fYwAORA1oWoAyRkE1n0AOv0Ag+GgrEkNnKqQfP 4AU7AAqUV7TUEAPnkH5dgIzUyTOTAJ7pwg1YQHmYIAT2INtDQH+1ggrY0A2GQAYy3QhogAxeBS8K BaLcOAM8YAQ88HICkDiTpQrr1gpw0LHn0woIzzAM+QALRCANAsBaRAAECsADYcYA5mKJUTa9TMQC wbBMoLVgsuBQQKAOAqACZ3C9deWjQ9QKAQN6qhB1oCoA2qANNmADezUHPNBJl+cDPpBe5MAC+kJC wUC9R3SAm0Zc5xAJMP0GxEAEFIAIEjsJa7BzglBJigpeyiAIrbAHIgDO/cQPHjABPMADtAAFMjAB 95gKoZps4XUOCxYKCbSsoRAGkUAMmG1FsJAO1GAH1DAJ9cMv2euJiUAEyKAAH7ACuIAFrdBT0E0B I6DbciAAAQEAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/pnas.gif R0lGODdhwgEQAMQAADMzmf///319vpmZzMrK5ISEwUtLpeTk8VRUqmBgsLS02jY2m7u73Ts7ndbW 6/T0+Wdns5SUyd/f7+vr9aqq1YyMxcTE4fn5/Pz8/UJCoKGh0J2dzm5ut3R0uXp6vXd3uywAAAAA wgEQAEAF/yAgjmRpnmiqrmzrvnAsz3Rt33iu73xvB4/NxlJZAAgBAwARIIiQiUlA1ABgAoKsIBJg aBGVwAAgECcCCsA5zXQ2jwfRoSkwitrPQGKALQXiAHwCAHNHARtaSiNsDwEeCQkiGRwKARSGSoIA UgALGmKaBWJ3HQ4BHAB/JQ0HA5UHRpwAVZ0IAo0ZYWNlA1xeWQiahXgQARJHECQMegDFBGsmCRZX CnizmL5foWKiY7PZwKIPFIo+5ufo6STFGBEKDwce6mRoCBeX5gYSFeVqdYEBCrRYwAUDAhELCBCg VQJBByWiOtwAcqKSBhpl0qRbwIDBwREILFDQICHCCQYP+v/NW8mypcuXNRpYUDCAQoALMHPqfGEH AAeBNXruHEq0qFEZAgYMmmdgaYkFSVEdTWFgwACGOpI6Tdfgg8qpYMOKHaEKgAEgGRp9eBAJAgV4 QBMMCVBkgwYGEpIlYDBAggIje/sG0MCHAUAKHh5MkNigwjIFAjlY0OAAa7O3BwpkkNBkwwguD6rx KeDgnggBCihMqFBCARLDZJYOuIDBgQEIjbwgAWpgw4EHGhog8bDBmJIFFoAwqFKWRNU5H9XMZa0v wASTavhyvhjYr/CAyS3gngDBwJWDlT6QyBCBwAUGBpJLYNCTtkQAGU5TvsDhgcHsfSnwHXHGfaPB BBM00N3/XxlQQAED2I0loVjWmYCEEg34x0FCl/AxjgAJgKaUZlJYUEABCCBwxQaVDABNMWmctdAH G9wHQAUHiQLULBpyCNBWDQBRnk2DFJIABhgoIIBmJDxghygBQMAFARC0aEgBe/SBRAQLbOBABsUN wgsSFEBgSgJnAYKQBB+J4oSHFIB4RQEdNLLEii1mUOKJCIRJyBTWiCKBVJ8FYEEGEBwACRolUGDH BBYcgUErHhhwoZ6G8uknL5g6UIFXe6KIzwRqTmjqqUSZ6cAAFURgGaqw0qCPRrHWauutuOaq6668 9lqrKIZVkN85BkzgAAqfeIMOQULJEOQUPQA7T0IBDOuC/wE7+qotWGV5UKE6GS2QQLM7iLJVKoBo 4oIpEtDSKgoXipDMRKWOkNyxM2SkDhO0iiDBBFSwZoKC2xY8VVnFXIKEAhcxcKw9GGAbQI4IVFIF qfZ4pqMB49DjIqPFOFBAJU444IQEOAFwwbHzjuDwErRV1QcJZRVWwAU4iZLMMtEBQEEGc5gkgHoQ FAABEhfFq0kYGTTA2QefKGmKSXRyIAUqzY2gQTCHiCAKxQ1EUPQVDXB8CS8ZA6DjJwzcLEYl9FVi EgVOjJDAAxJVQgE0JPDRxH0MwAJA0kmkvTYaAkwNdBoNbGB4QFyg0rLBlK+QdR5KnEGAERc2QujV I4iCb/8nXKTBCzTQyAjANI5hiAAFFwRkdxOcJ6GuJDX3UcgyF52ALwRIRoCmBATYMoopmfRBNkAe aMJLBxNoYEAlkVy+hQimSOT5CLN5APQUpXss+ggLCDOF6gBwJk0JSOiFBt8g3RH7kSmNcOH4CDkv xpRPBjD6LKTBAMAqR0AUnGFiJGiAAw6QDHGZ4hmhK43AIsAZ+izBAg94AAQWABVIhYEIBwhWCBfw gQM4gAsOYAABLCCACkyAARvwQE8c2IRIACBwAnPZBQSCw81MQAmlwIAE+nEGGxUHTQy4AGS6sIAw aIAjB6DONCSwlMCZRAMH2JsE5ZaodnHvArTIwBUGQZppC7CmAP9KFAYiIQAPGmoBIcngBnu4QASU cHP4ucAxnvKWCVzlRiFkHwEIQ4EqNIAk5FEgA+GIQQ1C8YpZNAsDjKWEOF4gARlwgAQGIL0CerJW nBnWAer2yVohIEGlTKUqV8nKVrqSciEAADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://jmg.bmj.com/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAAACA57iA5zRg57qSk/72kxb2kvf/27r2kzXtz7ntqzea0lN60nOa0nACL tACLrACDrACDpACDtN69tM293logWlogUlIgWlogOVIgQVogQc2klNWke8WklEogIDkgMTkgOZxB SpRBSpRBUpxBOeZ7Ut57Ut57WuZ7SqxiWqxiUqRiUggggyAglBgggyAgg0EgnEogg0Egczk5Yjk5 QUE5OdXFzWo5YnM5UnM5OeZiOZRBi5xBapxBc5xic5Ric5RiWgB7rAB7pAB7lAB7nGo5lGI5pGI5 rFpiYgBiewBigwB7zaRBe1I5xVI5lFIgEFIgIEo5xRjF5gAgSgBi5gBixXti3jE5OQBi/wAgUuak lCDN7ko53logGFI53hg5xbRBYgB7/wBirHNqanM5tAB7vZxig5xBe+ZiUmo5as3F9jk5c0ognBgg rAAgtLRiauZ7YpxBUkogMc2kpFogYtW9zQCLvd601Xtz9qyk7ik53px7vWIgGItarFI5e817Wnsp WilBpHspKYNBSubFvaxBOUFirPa9tINKYlIggzkgrAA5WlJBtAAgKayUvc1iQZRKc2IgQSAgvSAg YouD7rR7eyAgMUEpg/bFiwBqi81aQUEYMZRqcwApOWoxgzExi1IpKUEYiwCk1QA59vakcyAYxRhq nKRaWkFBSgC97pR7e/Z7SjlKvfbu1YspMQBBYpRKSv/utCApMd5BKe5BKdXN5gCUzVJSnO69i1Ip Wt6kgyAYKaxKSoNae/ZiOfasc6yDi8VBMWpBUt6DYqxqYmopIABStABB5lIYMXsxMQDF9pyL1QCs 3gCD9vbNnGpBrJQxMUEpvd5qQfbevc2snHsYKRhKWoNKlAAg7s2DagApnN5KMQAYUjkpQSlB7qRK auaUc0p7lO7NxWopUvZaOXsxczkISgAYvfaDWsVKOQApWsVqUgBz/5x7tAAIEL2s3gAp9vZKMRgp Yjm91QAISpRirEGkvSAICL0xKQAIvfaklCAp1VoprGpq7vZqQb2krCwAAAAAOwBQAAAI/wDdARhI sKDBgwgNunPH7Vy+hw+5cVuYsKDAihgzDmTIAiLEcxIpYryoseRBhg7zseDWMd+5lSIT7rpHs6bN mzhz4tw16cWkXUBfSColqcVPnTS3KV3KtKnTp1DJ6SDnFM02HVCXkttKdVu8bcG4ih1LtuzYr0y3 Kp0Vz6zbt3DjyhX7AaldnbssTdq715KlmTeB6p0E4m9OkiYTLpR4LmU+etzoLZxMuTJCxIopX2bc GBs2iBJDQ5YoWSBmiyMZisa82OE5ePAcu3zouvHE0worLmbheqJClPncHDs2KuU5zx5dgsSN+qTq xrR9KxytTswSKvA8a9cOEWbG07sdg/+U/pvbqwjMwhjLvh15xJgANE8uL3sleefqhogKc4w9d9Cl beQOPQROdp873dRwCQySnAPDJZbAN9A9m2wyWSOvmHILI1FEs497HoVk4GohWdRNOr4w0aAn5KSD WzrbeDDZPSHwwkgA+0RzxjbRJOdSSJABCNk5Fy2WTznk9CjRNuR0cRAf5AQTHwD3BFMIb9qVogk/ yWHTmH0AtmYacCxeEtk9+BSyjUFVQrPNPQO5yZFj0SjiETbsySYiSqax9BCL3Uh2TyGbkMNHQckI 0sWbVJIDTXwN5dOedrBll5J9RbK0GDcQIfmBQJsUAoCaBN2Tzj3IMPqEL4eidByelVb/OgpstgW4 kUS7MOQRDuRsMhAyJABQ6KEAJPNooXDy4QsykJ4jiYf7RAtrpV5GBt9ijQzIaWQ59PprsKO+WSWc 9/TqDijkCBIfQy/kAgY535QiKWyfRWRrF9AIsgk3EQ5YWjLmusPHo40WI4ggC5ULijrW6FAIZZDl 4guXLv33WIn3tEXOLJG4YC1FgphLTzLJXERClLuMFo8wmdgSDjmgjMmNHxPTBp1H47lTLjmrrIJO GyAFCDAILMVBwkXlDtLQOd2QA4QtyqSiCjnFwMkQkkpy1t5yABTjCzrOxBJb0AsB/MI5/PQwghyT jXP2OYqUE8Ip4SijjChIwAJNF1CM/1OOImQPGWtsZyKjiT+rkDKAly9xq8nNt81paT7cLCIBM8ow M0QnBtpr4GujhP5FLiBsMosJXPnyoWcOcVNIOfnAE4A28lxhiTwstOHNAN4EMMA+gZiCuRS2JCGL JbLIIk+JzcIT+gDBxJNmPLiAEw86P0sajSaepH2cN6wEsgYqM7AigDeGHMMKK96Ab4g9UmwxTzi3 XHGFLDRI15rzo+gRjy9o+AUKnHEAUmhCH/JwiSR2wARPvKpekeEUNkJHLy/lQx1KgBoziMA5ghRp QLzhHzzehQ5SoCMWBxAHMnJhCXo8pD0hYsy0WDeeRWRCFMywhTGy5UFthbBSjXFCCf/aAg5qgCMb 2cgVpx5YL9As8T9kwxB6RDGEV/BwIUN6DRApxw0SxMMf26gGOJyBCSV2BkTRyaJjPuaOTiTBFsyg Iud8eJxY2WYX+AiGL2YBjXUMYxoHyJUaffQxP4VpIRiCWioe8IrQdEaEttEZLTTxCxNkIxaIUMU0 +tSQlXgEJpMZ0iHdoY4IpCJzSejE0qZFK2vdQxDbQAc40IEJSACDGmOCDIE49R6L0ANLkVxIJzKB Oc2pgyWNeZWlrAUAZMQjGNCIRDYwcYADkARiobmWqxh3G24YQ5FCWERoeHPGWrkDGXzkgzlUMEZx 7MI5A5IQpBrCOhEtAgKndMAisqX/LQk2MTL0QMbBVCACZFgAGe+8DHMgBUxQLoII+VxEZSKVHPvc 4hekSEQvhgGNhCZGQMjMWRuJqQx9XjNIyYHOPurRi1CQghSw8OhH1zWayDXim8x4gEQtwss7aUcP lQgFImChC5l+NJSlMY0NHZBKxLQGItvJRzR+8Y1QVAAFRi0JFgmky6Q2YhGv2KdTgeOjfHyiBNJI QSQikdXvSIScybTPaBrBwwndQ1v54EcwglEOM7wBB6WohAkGcTC2ztRVTIwrQBcCDWi6Ah/VsAQL LhEWX3ztpb1AxCPSwZZ4fHChHlwlnmZFr2RKJBm+IIcv9joMcGgiHl8kRTrSQcBp/4CDFKuArWdp mlR5xgelnuHfrGjIAhb5Ax2+kIYzfqHanuV2G8SwwQRwQQp/6FaQoVkNbvA6L9L+NB34cAXPcosP RPBiFr4ABzj8sZV05AIZ4xjELFSLDiXizDa36SFe60irF+6gLb643io2hoxBFIIc6JjGKmaBBk0g Qhip2kp6W9glxoEylBJxifP6CxG9gkPBvmAvLYYRC2f4wx8mxN4YD7AB+v7iFxT2KQ1D8lbXwMMY WMBCbD6CjWiQIoUkCHIwflHNbGwjHYMQxzQ4UE1n6MBns2xETV0oKTwdwxjGUMcUVuk8LDRDFM2o gjYio2E9kEMflcgXMbKBiH8cQv8ThYAFNajhCVdo4RArdgZusYtSSR2DHaKwhRCMoQ03wOYYXj4l M4Iw5hfCIxqzoEX0TFDNDpiDBL5IByAPkA5yfGUQjrjDMDTBCymTxiPwwALUMlcGLCM6DM045d3E DBH+fSOahwPkD0IRijoBYxrAUK1S/nAEfuwAEOZYnmzmBWi7Zc4WzWgGHGWdimYco16w6scvNIAM WCRjHGlARp1KwWtef8MX2wBHK+qxjD544hryOON2btwMZ9tN1s6uNhZGMW94KIAUItDFL6BhjoIr IhQ/mAACGMEFL5QDDM6owwJSeItbtKHK7YGNMcIgChwyA9+Za8a+/TPaUUCCHL//AAc0QpELc/Ca gAdYxh7KEQouPGMZ1ZyGFfDwmUltZxTGqEImiGALj9siCIROZjJhtY8QQDMUwHAGMEJhjn8cYBq1 iIUOQkB1IzjCEcugBAF8brFzaEMd6jCGEjKRCWO8IgvZrTGesJGLdEADELiIBTg8cQEZWAHn4Ihe MDbhchhsiBEXlzcal8OQRnSiE3StjL8qdo5LkEIagvBBJSohW1eEwgu9mMUswIgDTwBCE8Goxik8 lswXVlQy67JMD7kxDl7sQF69eAQ06BCKYUgDH/HQBDiAAQmlnCAWrXhDgLcBhwiFpqyMD22BFLIO 1fqCB7koxiDowItTDKKx+CBF/yymcQpASPMArUBEMOKAiVa8s3NOZN48QZIrmvChGjnIrS9w25Zg wGEasXAC5bAO2fAHK5AMeqQJOLAOg4AMrgAL1XRSvEQa17I05bAN+MAk8cAx0BBipIAJW4EP2UBd jxAHv4ALf4AMyAAOsXAI6bAOIsAkZ2YDTpVhH6MQnBINW9EWA4YPuVAJx+UM0wBZGeB9eRQMq2Bd 8cALm8YLqdVcOlANY0VmzMRT+VAK83VcpPALhQAOv8CD6HAKsMBkDKAUhzNgW6Fuc7ANs5Bu4JA4 v8AaKFWFt3IksJVemIAJfxALIJhetHQAKCQOKFJC04AOSTgOyBAJXYEOOhAPq/8Qh+URHTExIJOw g4boD18DSL/wNSgEiK3ACZGgCdKAOC+lBZv3A1vBXqqFieBBUdG3KV4xC1v4ReCgAyWwDpGACFgn DBwghAzwCOzlC6sASJv2D+kwSzzzC7wAHr/UHZHjJzLgCq4wDJgwir6gA6RADZxgDvA1Dkx2ABwQ Fgj2YYB4AGoQCJPwCOjgD5rwBqVwTSDlGCxQGhT1CeuQd61FCiyYQoOAAboQC8AADIRACtvwCz5z CNUUc6VwDgxjCF+AHBexC0hwCzWABFdAVpSzSxDhB7/wB9kAC48gWxvgCJwwDWFzALWgi60ADgcA c2oAiNIwC+lgCHZgB/v2GRH/OZFIYJEAwBhORGUqIQyaAAt/AA6uQAzUgAOVUE2/gAnZ0AGtAAyO 8A7VVAsUoAX65w+q8HHW5iUXYQmoQANXgAqysC49xUUekQu/YFvgoAu4UE3AIA6HkFq+AAzPEAOh UAQFUAlz0ArZYAKGCA6q4ADM0JVEshFAMYmqwUUZ9hj4sAocUA4E1Ar/8A59cA1Msn8xlweeYA7R cA0oNAHU5Ay+cAtJ0HZjA1q8VRo1JQj4cAqIAJXAUA3VEAqekA7+IA3iUAvicACO0AR4kABSOQ7A 0JKrkANfpQ2RpBGSRxm7sAm6cHWIQALstQ2RAAu/0AdkQAnV9A5ckAAE4AegXIAM2SCEsYAKiHUf hzUgqoB+NxAW2/A133ANbOAJfeAIBvAMf5cHwLCSmBALDXAAY6ArXKSazDlGf5ABXkQO4rcM77AM 5lABO9BreLAM7dAKBdQz/qALzpdNAREQADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/jmedgenet.gif R0lGODlhwgEQAMQAAP+zgf+MQP/u4v9wEP/38v+gYf+DMP+9kf95IP/Hof+qcf/Rsv/k0v+WUP+p cP+yf//awv////9mAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5BAAA AAAALAAAAADCARAAQAX/oCSOZGmeaKqubOu+cCzPdG3feK7vfO//wKBwSCymAhBJpFBKJCOBEQQg gUAYjIEkEBEtBAOoZAEJACLaaemQJHGriUBAKzoDuBEF9x6ZAhB2IwwRBn1cbSQKfWdohyUQhFJd kAAATH0SZ1iTEZVMIpigEIoJJwUCEQxGq6ytrq9CSBIDDAQHAAkRpUpRImpWAAKqXGAjYhKFB1JU JQW6lcJpfr2ZEQQGIgMEncRWDYwR4QIISkkIqASoiKgKIo5r4oNJkFYLSqmSVX1WBVbWVoWSGNiW zlC4bYhgKVzIsCEsAAnlYCshh9wQBHJcDQgwcYYBOXSCbOy4kZrDkyhT/6pcybKly5cwY8pcIUuA MhIMSh2rQkWNoi2E8oDqRaBBUV/MRgRrRoCniTPbADSIgIpPnDmBZm1D0KeQgBML+oh5NyLsJxKQ JCqptUSfPrWijJXB58ba2Zl48+q1IWuPFgQLCGhhg2CAojRUpn7sIqIQFAWq6nxVUwKLRUUNnJbI 6o7bIktnpuSKkBnTAWuWFizgsourAGKeGm9bUEABKn2V/oQagIpTbouhyo2xpkDBggMFGEC2tre5 8+clAN2FTr269evYs2vfzr07dAM3JRQgE0dKR+QS2IzSYqAM2o4JLKaf7s7JehHqKYuHcLdfgfZW TNGPFQkUQAcENxlmxf8BmYmgAAR0tBeeG/YtkFl+ECBghXxspBcgBA98yA+C2TyIYBQBkHGASd61 6OIOsgBwzQjORLHTL4l1QYw9Q+EnQFNIRSdUNgKUop9S4UQWlmdJBQIYJphAksBfvUxFVWcJAUVA LwNkBgkJ4ejiCycmBIcJKjch8E0E9iDQ0YtwxjmDLDvV8QQ1vwgACRNvKIKNGEZJkACPR46R5RuQ hEPNGQeg8qMzfIRpRieSHELWCGEwMFUpl+ojXwE9hfnEXNd8maiZiCxC6SPhZCjnq7C2IAsZJGjT DgFnCcDEFNoo88YsAoQVAFcBEtBOoc6EJOhkSSFJBS5A8dHkqs581Ud8GJGQ0FuYegQnQi48uvWl XF6E6VYJqBZCgHy1hhPru/C60UYD20IwEQLbhMMMZVf86iAUArQjAlftiYrpqbgGudmqnUXaKjiG xJVemAQkkEuD+jgQZnABbBvlxmQNxImkEgs3wGniJABOwvG2LKcBgTXr8sw012zzzQyFAAA7 ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://dev.biologists.org/portal_imgs/search_result.gif R0lGODdhOwBQAPUAAAAAANXm9ubm5vb29u72/97m9tXV1f///83Nzebu/9XNzcXV7t7e3t7e1b29 vZSUlKysrNXV7qSkpIuLi3Nzc8XFxYODg2JiYrS0tFJSUjExMfb2/3t7e8XN7iAgIEpKSmpqatXe 9kFBQRgYGDk5OZycnBAQEAgICFpaWikpKe7u7gAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAG/sCDcEgsGo/IpGqw 6SwiocAimYRMMJIB9SBxbIfaQ2GcIBS+RgnlgMmEkaUSGqlozIkQjhAkQZQcFgIGCH4VEiUMGA8M EyUgBg8SFhgcKgYSEIoWCBcPd0N5QhMfJZKRBlaShxQqDhQgDCUWIAIUfg9XICUTDhMWFZ9CoQcX FyUDAwIoFRAPyHEoBwIXFAMVE3oTiRQWWocIvsDBDxcMuAYfXQcUBgzpFQ8Pkw4QFBUlnCoctygl 8LwcLMgJhsBBBQRCEEDQEgZBFgMGBjgwcAAEBIoVVCAQxICBBBUMDAgSIC6YySHlTg7pyLKly5cw Y0KoIIBBzZY3Y3Y8MKKn/s+fQIMKHeGhaIqjGo56OMq06dIURaN6GIHhhNWrWLNq3XrChAmfX39O DRq2Z1kTELyqXcu2rVu1PqPGnQtULtERaN/q3Qt36N27Y/3m5UvYrV+6h/GmLcy4L+C6icEubsx4 qN3AYn8OplxYLGa/ds1O5rw37mfEhzeT1tuzaOTIGFbzbX36Ne0RDmSXJlr78Fi5ub3i1b2Wd+/h wk3T9hCcNWXIYO+ayNraNNTmb5F39my2pwYRGYpRuJCBhAaxUJkDbat9N3fkIlCg4AABgYEKlDJk SLHcA4b1bLU3G1nTiUCeBRJgUIFB21BAwVfp+QeWYc8JZUJ4GXBACQUP/nBAAQcTcTABBVMtpR6A cA3YHW8/ZTAKCPJ8SEEG4P1SgTETjJCeAxaq5cF0QAY4FFQ9fWABCkZa8CEI8n0Q3wMClMBBBSCU yKNZbv3mU1dqdSXUWBR8ICYHTF4gHzUikIIABhSUgAEJRf0313QjpHkBCEteIAIJKXh5nmM+kYAC CR9kMN4HKJAnX5oTFMSNK1Nd2RMJInigAQjx+YJkBol+QIJ5e2oXnZh74inmB2aSJ0J8Dqggi4gp aFABUHuKeSkKKfgopgco0NieaUx+oMEFTqZZqH4opCmBAHmIKIIGwYElAgeIPqvBdK5p8N0HAgqX AgkTgJCBBkjWKmYG/qT2o8gEDzhQaWzJjQACB5wauKcGnyb1LJ99pZiCBbPQSCmn8jEZHgfyTMCL AB/4x1YKIz6LbnyFelqik1a9dQIJxVxA6QcggEDNLBcgOMsDGBjgwHnwqiUCNuV5iqjM2o4gKAgj ZJxlvnvqRykKTAJdgoPxPHBeCtidQAoFveqnAaeelqdBoSQCwCVbUzuJKqF7gncsyMZYYQG3VLFF giR6Iipyor32PF/Ohq1KKNAxr3oupxmAsCAuD4hgArxWAWBCPBboSQKeDnoKXqIgTKdzlyk8m97A NKbJKXkceIjnKH93eQIAKDhQQofUOMik6dx8YHVXV3dlK5EpRH3m/odkVjn1vPy17Pi8SibbNI1q i5tBV+ddbQKh5iU1lZgXeIhgs+WRwCmTZXtFvAVppudUWeR+ey3W35nH3wj6zZw3B8YIa3neJEBg vAgWjHIUpU9pUOK49uZ81XSRyw1VCsgCAcA0Nwp8IQtJackY+TJwJG1pq0RQMQGv6jSu1WXMKlz7 lHnCUyVKPU2A5CmUmUCgAQjgxUT6mVbyIuSa2OGLBI7T2QlGkKy7rUpk+vOACD5EsIPBEF7xwRMJ KXCvF9ovZyOwlQZWxxZEpZBQ6OrVB5BCrl6ZiVMzGswJGEiNqZWHKa4hiqBEgCkAWI0tlrsXf3TY q6JYzjyEEiEH/kSwmBmiYGq9mgVSiHSnPfUqBWbk0lVQRaOk1IxcIugKePhEqU9x8AKxAUyvDueh DJjggWQ8j75IYEYLfu5fIDjXnazotxFkDQUWIFMxQoYCeE2lKxPIgKXIqCM4CUp6DduTBdUCgBSg j2mJ8piDROCdntEufuFKwX8iaMYMieBbGThhkUpWKRR4oJOs+5wGSsCn+DhIUPopSvhK5qD4QeAD J8CAaz5ntVRZMyzZqpSgOhnIwInAAXpSHsXGcxQ/eswDhXoAAjiwGXYCAH6EeuBTIscnCnCSnlcB QAYqIEVrUSpz2lqVFKc3ExSgZTiBO0GYvBKr/4H0eKqDaOAu/oCAJkkudpjSl35OJ0AMrOwEJrSe GXcoS5v9KDkmEBxAR6DSz0GyokuZGhGTIj1DoeAVE8AECXCKF3aagEmO1JP2omKCWD20np+jQBvQ dSoxWeCBlyoZAzmUIHSasKq9pJeRyqU8pJTHUpZUKQBAgAEpFktMFPiWKakhLiWxywGWjA1Ap7jD ND0zqURqDQl6cgFAzrAnn+PDxCqXLIcyNm8H44YFHPABE+TmBL5c2w6ZRpSS/qip13JS7Cz2ORTE Umue2pTcxpShgODCATAMjtL2g6oRFU6CD0wB02jEUPAscXUlcxKlNOpEAwpwPgjDBQZyBTgAVLF8 4DHlp+qk/ie5vTCoq0sBCh4gpk8dK1F+i5wQP/SA0b3JtHDt5SjgFLkImfKZXUVVn7B5yXRAbWBn EgEAOKYkqMYBZSjADWY7maw36qxIUosVPVenrBSuanFikuh87sSB0UHgEIkFqdU8JUGo7K+eAJjl hq3igQw4glR74hiNQPdU8VggEhAowfASGDgTIMkE8bFWGKcDAFOWdsZNLlx8CikoMZ2gdCGjQFRn coEfVYWdJ7jUzZIHp6dMhX9wspoFrRY0w3mRxRcYEdAQ5ABOzPBvEd0rCec4labYz0S2HB5YzQi0 YkgXWVMt8SsQ5g8ETLUnX2YnB5CEqxNCJSnDqROcngzj/l4WOllevIAGrqyGeaEMARW4FqQdZ8Yy 4cor9ftpUolJzEFfKHZmclJ4unzQVH5IAiqzQK56clozXnVaxCqlUXoiLq4dD5Ce1AAFtGXoQoXy cyQIiAAREAsODBs31vMK1GaUrK7GqsbkwZM8n2tBD0x7anrataA9MC8t3yeqMCRKcIoiQextLZoR Ehc39hM59AbSuxNInqEpTVQPxJldBpDFAya7lNxYKlbxIZb9rlVk9FGrlteEaFz39K0wlUeWTbZt HyQQEGFHZWVk7h9UxrW/ExhoPNqCNjY/R8NnFeWp6uOkCT4g0BtlrgTcmgoGXuhYARYysj65lCN8 WlTycyXl0m3kmCIvoqSATEAu/2khuUDAp3P/BS8asMCmFbxzwQkr5zpMJLjEWQqggWACF/iK0stC FJDl3DxkOaSgseldUeeYKSegtzjjp8qxzXDvX7EeubSlwbN/JVQAJOrOPxCmYvHplYKLXN5CNq9E 3gUDQQAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/develop.gif R0lGODlhwgEQAMQAAGaMs0Bms4GazZqzzU15ps7a5yBNpkBwn/L1+sLO52GBwKG02RBAn3KPw9vk 7YGgwDBZrLLB4NLb7eju87TH2ae90/X3+lmDrI2qxpGn08HR4OLo81Bzuf///wAzmTNmmSH5BAAA AAAALAAAAADCARAAQAX/oPeJ5GiW6Kmm7Oq28CvH9GzX+K3n/O73wJ8wSBwai8ijrzMocTqNQaeQ oBYUhA5G0GFIrVUFoAPglpiBDmkMSDhE6cCoIxg7qmG2yKxXJv9+gYCDgoWEh4aJiIRMJREdBiNl A3IBAwwjB3Uek3KcZCIMD5sfBgOmpAoPlgIHqAAkFwIDCiMEAhcNGJEeFB0UnorCi8PFxMfGycjL yisHAQC8L8/RLwTSaR4EwTnQ0i0M1czjzeTm5ejn6ukmHe7vGQd/feseBxmw7PX6/Pv+/QDPNTLB gE4WCtoSdIAwIcGIAhIOansEgY0BKCM0dNhG5wMDBxs+KGzwgUsEV3QO/yAoYG9BBw52IHyIMOFT vn84A+rMyXOnzzPAACgo0KGCtg4ODBxwKUeBuwb2ECT9wJRNwQUHPiJ41uEkBAsOq8Dp4KkjggmR MnQQA6qkmjEFvv2c27Mu3bt289rIhrev3r9+AwMmtAIAtAAECIXDNFiw48aQH0sG0mEBAA4VJFQO FAdg58igJ4sOTXpGxzVaPFRAiqDyhQ4PRDiFsNpB6wUfOguwIGFC0U8dekPxUKD1hg4bLCCw0OGC hwcdJrSOkLtDa80CPmiWEHu099Lgv/s9bYtJg8oDBPjCcN5AFvboBaymRBa6CQhQxiT+0J6opLZo dJWeFPRl54EU1XEjXnx4DC7ooDrkeaARAbNlIkBiGvRGXYX2XBjHefJ88ARb+6nFABX/5RNgLXtw 5AmCnz0oY4M0zqjIO+4g0MQID7TmjoEfLEdCj/AkmBtRlSU2hi/IJYaiTSI0coGPm32GoAfMaVDj ljZy6eVoY3Qp5pdkjmlmmWieqWaay4QAADs= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://mcr.aacrjournals.org/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAAABAxYhCDewhaampqc1JSWhhqWrS0vQhBOQgxIAhKSpSUlAiLezEpKSA5 gwg5OQAxKSAYGBhBgxApMXNzcyCkgwgIKRAgORg5cwhaWhhBWgg5QSA5ixgpc3N7e1paYhgYUhhB cxBSc3uUpBBqWghBSghKMaysrBAQIAhKQRAIKRAYSlpacwhBYghBQTlBSghKYnNze4ODgwhqUnt7 gzk5QWJiahggYgggOSBSiwgpQRApIBAQQQgYORA5WggpOQg5SghaSjExORB7ahg5gwgQEAgpShAx WghSORg5YhAQShicgxBaiyBBiwgQMXNqaoN7exAgUgiDWhAYIAhBWlJSUhAgICAxczk5ORApORAY OQhiWhhqg1JSYhA5Sgh7akFBShgYQQhKWgg5KQggGBgYIBgpYjExKQhSYgA5MQgpIEpKSqSkpBgg WhApUghBKRg5exAIIGpqaghiSggpMVpaWhgYGGJiYhAxMQAACBBBShAxSmpqexAQOSkgIDk5SiAx gxApShiUgwgAEBgpUiApcxBaagggMQgYMUFBQRhKi0pKUpyUnBggShAgSggxQWJaYjEpMXODiwgp KRBqexgpaggAGBAIGBgYKTlaeyAgIBAYQQA5UiA5YhAQKRBBOSAgGAhBahiLeykpKRgxYikpIEpB QSkpMRgxcwhSSggYGBgQOWpzgwAYGAgACJScnAggIAgQKSk5i1picxBaWggxOQhqamJqcxApWhAY MQgYKRAgQRAYUhiDnAgIMRA5ORBKShAgWjlBYhBSg2JaWgAxMSkxMRgYOSl7i4uDiwggKRAQMRAA CFpSUiApWhAICCAgKSlBexAIMUE5OQgIIAgYICkgKRA5YgggQQAAEBBaSlJaYggQIBAQGClqg3tz eyAYIBAxaggQORgIGBBKOSBKlAgxKRgpKQgIGCAgYhBiizGslBgQIAgYQQhKcwgQGDkxOQgICGJi cxgYWggIEBAIEAAICBgQGAAIIAgxSlJKShAQEBAAECkxgxgQSnt7eywAAAAAOwBQAAAI/gC70etG sKDBgwgTKlzIcCC9hxAjSpxIsaLFixEFUnTFsSLHQR5d0esokSPHeBgJUux2r2XFlvck5onXrUwZ TODKCLT3kCXMe91c5amocqBNm5rgFaiiyc5RnUIKLBqV0+a9U2ASnYIGzVqNKtCOnlpUQMgoIYvA QHP6tKdGU1X01dFn6oMMCjYWrdG3qJkNAh7krFmzyEYzOR4+mBo8uG4zfR8KgCHwr4ApMHX+xdA3 +EOdRG7p5WEz7dQJV/dq/Iu0xma9PFVoWANTQ3SMf4v0wdtXBkCZga661QP3akG3aaas5dl3r1kN 4d3kfKDHs+iJZN8O/KOxoPsJNnJk/hQ4QUDGiQM1hLABUONE9wX/oMhhk+yEkFMHXv07wGYBgRNQ vMIIfTTIQF9o9MiwgIKvQMIfG08csMgrMuT3Sn6+sSEEBQcckIyDd1DwihwLAIDfAmywEQMb/C3w ynUE2CBHHcZlU9QiadVRxTdy3HFHHRQwkgwjH3wABXxcVXFXcXXAVVkMzRQAjRDb1EEjDf+sIYMM rzzRjBA0yGFKMwgKAcaZicBzRwHwTAOGHE+YUkMNiTwhR1ZgTDNNAQTIscg0WCSCRQ11fJDIoViE uMagVdi5xjQ1nCkEgnlUmocr7JjVTaWajFIpPdDUgMVvli53ihBr3VPGKGe8dmkZ/kLUYI1oeWQq BKmfDqSRRBrtQ1E9D/kaUTZD+aQRT8E+BOxDIu2zK0RFrXRJTz3ZERNBywpUj0AaCeeQWwK19OxE 0co0WR0hylGDDVAQY8008sgxYyJm4oVXVGBowicfNZgihw01NENBAUMRNS6vBQHVzbRuAZUtUNdC VAY03Gq78EW9PnQpSvZYWtGyEyE7UcEgYQQtsAT1u1Qda5hiyiLj7mPFFN04y+0l2dIjrESX4NwN zcr2fMnCNdcDbD0o5LbNNre88MIiNYD80AQTvDO0FRPQU08R7zzkSS4TWFFEyfRMkcUUKEwwBTrd oIAOOlPscwk6XTu7bB3NdMEK/is1LPJB1RDVg84EWbzNzQXVvMMNLO+AhMIFsOABOD3vTICHFSi8 Q3ccKNBDNz25cIPCJAQxnEiRrGRCQJGzfPKOSPXEcggd3FyCQhaeAGOF4coow0093OSySy6TjFEN RINUMwE1ccThCR7V6NL7GN0Uwc1DkZqyTSZ/nGJMJyQgYc47kyijxSHBP/Q4Cn3oMgYidFRj9CXL ONJDCrAwPhIdc/yQRR+OyMJAqlENZUygGtwASQ3GMgtWXKEdOIiFF1LwBmUEQRlOoEYu9PAOC1CD GipAhzlM8A5zwKIe1EBHLFrwgEC8Qw1do5wCbPGIHmDjHSBDxx5EUYJqHAIf/pb4RAU40Q4j/EAN ytCFC5AAQ3RM4h2quEQfehAFROQjAyScRDXQQQ0cqOIBykDHRC4AA11QwwgnjIgn1iGKGSwBAbpI gRTEoIAU/AAJD5hEBoKgix1UYw5q8FY+6jgHOkwCFohwBBcPoYJ8lKBxEUHHJVRAD10gAocRqYci SKAMJm5AAUOYgxRSkERd0OMCsdBFEMaQhiHUgh7xeIcyEkcPAm6iDRYQnDjaYARd6KEIDxEjNTaB iAEoQyQR2ccKUggSc5hjEkiYQeN0AQQU6AEBsNDiJL6ABl2ghB/MuAQ2gPDKPvBCBcvgQR9wRgIT DEKM9PBFJchJkXGoAh3A/kKHE1wggCC84ZBvOMQkRKAAWLytGvnYAhK0Vo+ebUIXCHQCLpahhBv0 oQ8qOEQGuAFJFbjheBIxWjdUQQ9+iGEICRDEOpAAgTnMwQSWiGYFUhELHTTOAOswBz9i4YTrUQME +XiHGcwAgj6sAA6eoMYwnDkHengCCEVAZiR/QdJBbIEBJpjBG97wjjkEwQLSsOQWBOECMRwCFkgw gBg9EYsUeqIDMDiEFrIQC25QIwpmcEIPfgCEIehCCz7QBTwjuYV7KuMLQ6CDCZShABfgz4SPCIQv 3oCEHvBAAeZApgqpcT0tROEQRYjDPGLBgwDkowe60IU4EAEHOOAAEX2Y/gg39kBSEwjiDUp8QCq+ 8AVVIBARKZxECqLgBv1pbW7o4MY6B+ECBPQhCpYQwRDSUAImHIGLIZCAE/ZwBGpI5AcX6MYbUoEE VTjhigJgQCoGwY9lueIHXwACMsiBzIYuw3OVAEEclDGJKADBCaLYQjHoEAUexAEdFljGJbihhR9k AJP12IQjLmELKfzguQHIwBhqMQZlQQQdJRAEGvBADZIKrg+Cq4UUzKGCPoQABgG4RjVgUQRm0EOd e9DDPK6BhkmMrw/S2EULduGJJcwBHTzYBSWOrIsvdBhkrjAHA4zghEMMwRBaoEccBlECAXwhBTeY RwuGMQxu8ONtD1lF/iVSkIIw4AIHdMBFG7TgiSQAwxFcGIIOVKAFR2xhqwSsxhsyiY5H5GMA1RgD JWwxB1VY4gEZUMYmzOADWEQBF1oToxgvsYkteFEJ7hBDJdrQBiqkoAe9qEAFMhCLTWwCByXosCve 0WGI9IwbP0CDDtBABwVkABYpeAAQEHENLkihBLGIwgXmFsxwiKMSw5hDCLagDJzRAwhL+AEMBPEF BaAPFjpoASddQQdRKAMiOIxDONDggyVkQQWo6MEcuKAON/BiE7BwAzpg4APPvS0OQPDEClqACxHo 9BnPYIYeBOGOIWwhFaKYgyOUIQU6bKHeMPArNyTJRRWEQwfBAIIS/hShDmxkoRY9SOAgdPGA0Dni vjisxyDoYA65AuF3RuOHD75whF7s4RpbYMIWoqCAVCDABUNAQyzckWWjSQMVIqiGCmTXCC0sQwJu 0AU34jGIdpRgGI8ARCW4yDx05BEHVNBFe3uGtFjkIgdmgDoltkCJDCxBFECARTXoQIkLMKNruOjF FgLxiVSUQCTo8MSB8RkHLgjgEIewoRFI0QYzAEEcuMh4EQQnRmDFwxVhUIc6RIEEWFRwCKJgwBCq oYN1fKIaUhiDIQSBBHUswfDAM7PnuhYLQQiCi54TQwhugAsdSEMRW6CDMoyG5sAJYgjrkAIsOMIN HHyBBJTThu9S/jGJScDgCrswBzZs8QNubPwh96YHDrYAizjQ4RLKQMQyqNEHMyhiD+bQ9zOMJhEk amMILsARJUA71QASreBM/oALdIAOV6AIbhALJYADmhNMm6ACg7AHFTAG6OACR1ABIhACqAACRGAE KhQF1GA0UoMCl8AP9DAJBsA4CvA69DAIkzAHY2AClSB0xDYM6oBR4cQwruAIPiBCQ6AMN3ADiIAM vxAMufBT/hAFWtADleAJNhYRqzAtyWNkDyGD6MBflLMMjwALniABe3ABG9dQOAMsONALOJBch6AO OXADhVAISeAJoWAEUdALJbcHdKAKR0MP4jBhETEJZOAKOgAD/mKkOW8zgeiQBHDADUWAT8ByCYqY BboAAiCgC4+gBTwwDzewC+3wBZqjB3tQDeaAADOQWfGgC6EgAl0DLK5geq5QDa7XBxuXQmjWAr0w DO/Qi8fDf8pwCK6XQppTD66wCZWACvlAByLBDMyADjMgChnwAMpVCTqQBdqCbvRgDhUADIBACmH0 EObHUdyACNWAA+pgAK5gYyWwAQZQDZPgBLHgOfGwCk3gDjkGEkYTD1TwBT/QAwFQCCBADcvwikdT D72oA0yQV7qgiBwVDyhBCpugDgKgDQNID4cQRpuQCisgDbt3CVqgBWKwB/BkNMvACyugBeIQBY5w BbKwLCgI/nzUQAqe4ApixAMbAAsaQwuiwA0hAATowARMcD1OBQg5oAUiQQ3l4AaukAsCoAY2GULo sAlNwAFt0Ac3wAHl0AkMozX08EHxEAvogBIldFh74Avv0AoGYABaJkaO0Ab00AbqQAodcJXo0Acg cATxlVwQ8UEqRASBEAu8kA6OAASToA5A4AZnqE8IJkaukAU5lQEBwAPokAJ0YA+bwATn5gBXUA9m gAEOcA27sHEgUAmOFALJBU/JxQ1HpQwo4AmwNBC90AtfAAvvpIgQ4QrKIAi6gAFHMI4qlARcYATc cAOAwA2xIA3BsAs4QFYe9A7UUAm9iQqJSA99kAO9gAv1/oASECECovAFYUSUH7YMIkAJbpADS3AI 80gNyNALgEAEIuAD5fBTmZAETlAL6qADvuBdy9AEirALUcB8d9kElHAE78CdA/EDW2AO6CBYVRhD TeANQyABDrAFWyACG4AOXiAIXoANoRA/3AAHI9AL5vdOsfU2GMAEUVcN1FBX6LACvQAEYgkRRdAN FsANaJAK+aAK75ALVxkI4bACu3ANdqUAX5AKM/gJ5vADAjAHrgAEolAOMEAGyKk4U0k3jtALTKAO waACOKMC6jAJZkAKyNQNGjAH3DAEXyAAtiAGbTAP/bCU0VN5YiSeg8ANTrAF2lBJOrk4ASABr9hT TgUH/jlwDZSAM4OwDOUgVCHwit1gCGxkDtXwAy6gAxdVCJXAA7qwCVfQBJYEUrvnRNXgBsOAPHRg CPDUBzzADbjAAdeACJhVDQ/wDoqABulABLrgM2EgAqmgALngAMCwcdzQBggWCxwwhYHQC08UTIU2 BALABFzAncASCIqwCddQCR0ABEZgWddAArCwCQ7gCD8wBKTQDgw1DqnwDtlgAMiQBGxUDV7QC2aA CEDABMjgDQGAaHQQQ/SgoBWgCIIAlfQwLVPABbgQCkeAC1QGAjcQAEPwDiBQDrhwBTrgCO3wO1pT AUNAD3uwBfaQAUNAbDCQAwGACsNgBI5QDnTwYW8T/gtZMAno4ANWcGZdww8b1webgApXMIdX4F1c tAKxYAabCAc98JWhlwHo4AZMsAnVAAM3gAGkkAtuoA4PYATp4Ab5sAlb+DbpUAjoMDaeoyzcEApa 0ARMkAta0AY8EALVcGbwJBLcEA6x4Apa0A/AswHVgApNwA1uAAi9cASW4AMZMAg80ATAMAfEChJv cwUYIEbKgA3z+BAhoAjB0LCkEALoAwM/AHz89zYplweKigK08AXmsAlaQA2FgHVa0KDHowUOAFHv sAxXOY8gYAaRqAyOMI+XELFwQA/LUAhMkAOKcAg84A6P0A6XsH+xEJou9gnLmwQCkAoZSg8WEAXq /uCz/qY4FmABsbAMHIAKaWsGPQACm9BTm4CX37sMkxYAFoAL4RAK+QAEoQAEg5CUDkAERBACtLAM 6TAEs3o8yeUECtCQ7+AJRAmdFiCPACkBgOAAywAIV+AIF6AITdAB2OBqgCAMMlAFkrA3I7AImfAK HrAGfxADBMAKtyAM+PAO3TAHBqWIStABQ6g5feBdlGgB6dAPWrsCElAJK5AObQAHj1ANk1cIUcAF PjAPziAZhKEP+mANf5AJswAGWAEGLCAPp8BFx2CJ15oO1CBwlNmL15NcLYoKXtsODlAJUVAJ5aBI VICIyyALV+ADjjAPy9An0iEPJswHCzAC29AF/s2QDfMwD/RwDG0QDbtACyEACEEsfyknWH0ZQ9zQ CI5oV+rgDhlUCVzgDooAB02ADbkQDNQgBEKABYsgBCzACosgDJkQDdBwCkdQCDewCYXQBDlQDlwQ C4igA6jgBlcgAT61DG/TfNzQD2OXCzqgDi3AA8tACrVgBIqQAxIAA13TDTEABXVQA2UgDPkhCZ3Q MYMQAlxgnFGwCS0QmpQgCJTQB/PgBorQOPNQCJ7wNoLDNSCwutdQAr4bDBJZv7sgAaiADe4QC90Q Ka98Cp7gDITQCbkgEvFADeqwB1fACxYAQBuYfJsACCuw0ZuQw06ADssgOKFDOQumBfWnDk3g/glG gwJy6AS9AAyXIASJAA7wIASCGcYIGj3pBAKycDzX0ASooAJyiA6OAAflcAVipATcK7yVgAhOlQPC 213Lgg5R4A0rEAL9Ngj16wr2gGSo0Afy2Dn+Rly44AzHoAdc4ABa0AhXYAa5gAK/wAWEcAm5sAzL 4AmGwAXR4AkosAresA4ikA4szHzIsA4hsAtTsC1E0zZm4AAO4J8iMAVxsNZD1QgoIA+3wAfy0AyY fQs28AGQcAueIQ+QQAzEAAmYXSjyIA8e4NmmTQx1ENqswAeeUQembduxfQuYzQc2cAuzENqrDQmQ cAd+EAERUAoNMAp+0ADMPQoNcAajEN2a0AAKoGDcVoIFaxAB8OAHfqDcfpAUmtApzs3dkeAHiXAG 3L3c+uDdpXAG0xABoNDd4a0PzfAYkFAFxPAYdzAYkNAAVqAJ4DANLrIGctAAPYI36DINP1LaPkIM VXAHVWAD/yAD3xADd4AdW/IP30ABdtAp1hDexh0BmiDi4AAOEQAO4Z3immANiWAKumEK3q0J6c3d 1mAN3c3dZ9AAncLcyb3cyZ3c1jAK4V3jQR7dRn7kSG7kKi7e5xDd59Dko/Dk56AJTR7eQq7iV77k o1DjAQEAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://www.jneurosci.org/icons/shared/searchall/journals/molcanres.gif R0lGODlhwgEQALMAAJKSycnJ5GlptEFBoPHx+FxcrU5Op9bW6+Tk8YWFwqCgz62t1nd3u7u73f// /zMzmSH5BAAAAAAALAAAAADCARAAQAT/8MlJq7046827/2AojmRpnmiqrmxrOoI0SEDw1BQsOE+A BIEDD0YJACTGm+0haBCOOIvBUcAYFj8mTwKL0gjAgG5rwRUcDOQvyEs4FGqgUJIQx7zJSXTn6vv/ gIGCgysOBAcSBgRgGXwkXh4ABDMTlIFRCg2EkISdnp+goaIlAlUXBgIGFAUClAMxFzEDqh2orRMF M6YYr7u9Jqi0TLsPwTJVBpYVxqPNzs/Q0SAAxA8MCRkGRyQC2CICCkAAaYICAOfC5d7S7O3u734w ZwgIA1ELTwsO2HwDBA2S0gggsAAAgh7bkuAIsEABEQAHGh7E5UCZHiNPtByAiOhBAwQA/wr22HgA zg4FktJB7EbAmz+ABNIcaJDpwcuADwhkmnQjooJ6P2qYAyMJDryjSJMqzQHrYjEiD35qeZCAgKk0 DZbMaLDAJkglD9A82Aj2QoGMMgAICAAn3FQupaDO2iehlaMySx4ggFP16itrbaxKYLBjwICHeSW5 2kNmqePHkCNLnky5suXLmDNr3sy58wgH9SjmtXBXBKcO+NSCIzDIYEiogk57nk0bHhqCAw4YyVsA Xd0tAxJQm6BteAFax8EWN2Ugl9oKLS8EHyej1TlLDAAkoJSd3F/tFTDlnW7KHgBa5CX0Pp/IuSzh aWpoW1e7vn1nRPqCPUNL0lS3VCHCldsMCCEBhQ20KMSTMqVR0J8NhdlEBX8yMMDTFK8QYZEkYmgi AYAJIJLRDCAeYBhcNyxoUCUQDcbafTDG2AlsNNjQogxU8DFgDuQY6CMOmRig0GgURHQBAweYAyEZ XXREw0QTNOhUilt1VYEAe3lk5QQbHXZHXmxRwJiMZJbZB41lVRUEAlU4go8PXRlwwA+snXXAnAd6 BAY9whG5SgBgiHGANg4EodNdDxVKlhtrvoXXBG7E8CYCXR2S5QOTLjAAPYAe0NtoTvig5G9mlmrq qaimquqqrLbq6qugRAAAOw== ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.jneurosci.org/javascript/ajax/xmlhttprequest.js /*=0A= =0A= Cross-Browser XMLHttpRequest v1.2=0A= =3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D= =3D=3D=3D=3D=3D=3D=3D=3D=0A= =0A= Emulate Gecko 'XMLHttpRequest()' functionality in IE and Opera. Opera = requires=0A= the Sun Java Runtime Environment .=0A= =0A= by Andrew Gregory=0A= http://www.scss.com.au/family/andrew/webdesign/xmlhttprequest/=0A= =0A= This work is licensed under the Creative Commons Attribution License. To = view a=0A= copy of this license, visit = http://creativecommons.org/licenses/by-sa/2.5/ or=0A= send a letter to Creative Commons, 559 Nathan Abbott Way, Stanford, = California=0A= 94305, USA.=0A= =0A= Attribution: Leave my name and web address in this script intact.=0A= =0A= Not Supported in Opera=0A= ----------------------=0A= * user/password authentication=0A= * responseXML data member=0A= =0A= Not Fully Supported in Opera=0A= ----------------------------=0A= * async requests=0A= * abort()=0A= * getAllResponseHeaders(), getAllResponseHeader(header)=0A= =0A= */=0A= // IE support=0A= if (window.ActiveXObject && !window.XMLHttpRequest) {=0A= window.XMLHttpRequest =3D function() {=0A= var msxmls =3D new Array(=0A= 'Msxml2.XMLHTTP.5.0',=0A= 'Msxml2.XMLHTTP.4.0',=0A= 'Msxml2.XMLHTTP.3.0',=0A= 'Msxml2.XMLHTTP',=0A= 'Microsoft.XMLHTTP');=0A= for (var i =3D 0; i < msxmls.length; i++) {=0A= try {=0A= return new ActiveXObject(msxmls[i]);=0A= } catch (e) {=0A= }=0A= }=0A= return null;=0A= };=0A= }=0A= // Gecko support=0A= /* ;-) */=0A= // Opera support=0A= if (window.opera && !window.XMLHttpRequest) {=0A= window.XMLHttpRequest =3D function() {=0A= this.readyState =3D 0; // = 0=3Duninitialized,1=3Dloading,2=3Dloaded,3=3Dinteractive,4=3Dcomplete=0A= this.status =3D 0; // HTTP status codes=0A= this.statusText =3D '';=0A= this._headers =3D [];=0A= this._aborted =3D false;=0A= this._async =3D true;=0A= this._defaultCharset =3D 'ISO-8859-1';=0A= this._getCharset =3D function() {=0A= var charset =3D _defaultCharset;=0A= var contentType =3D = this.getResponseHeader('Content-type').toUpperCase();=0A= val =3D contentType.indexOf('CHARSET=3D');=0A= if (val !=3D -1) {=0A= charset =3D contentType.substring(val);=0A= }=0A= val =3D charset.indexOf(';');=0A= if (val !=3D -1) {=0A= charset =3D charset.substring(0, val);=0A= }=0A= val =3D charset.indexOf(',');=0A= if (val !=3D -1) {=0A= charset =3D charset.substring(0, val);=0A= }=0A= return charset;=0A= };=0A= this.abort =3D function() {=0A= this._aborted =3D true;=0A= };=0A= this.getAllResponseHeaders =3D function() {=0A= return this.getAllResponseHeader('*');=0A= };=0A= this.getAllResponseHeader =3D function(header) {=0A= var ret =3D '';=0A= for (var i =3D 0; i < this._headers.length; i++) {=0A= if (header =3D=3D '*' || this._headers[i].h =3D=3D header) {=0A= ret +=3D this._headers[i].h + ': ' + this._headers[i].v + '\n';=0A= }=0A= }=0A= return ret;=0A= };=0A= this.getResponseHeader =3D function(header) {=0A= var ret =3D getAllResponseHeader(header);=0A= var i =3D ret.indexOf('\n');=0A= if (i !=3D -1) {=0A= ret =3D ret.substring(0, i);=0A= }=0A= return ret;=0A= };=0A= this.setRequestHeader =3D function(header, value) {=0A= this._headers[this._headers.length] =3D {h:header, v:value};=0A= };=0A= this.open =3D function(method, url, async, user, password) {=0A= this.method =3D method;=0A= this.url =3D url;=0A= this._async =3D true;=0A= this._aborted =3D false;=0A= this._headers =3D [];=0A= if (arguments.length >=3D 3) {=0A= this._async =3D async;=0A= }=0A= if (arguments.length > 3) {=0A= opera.postError('XMLHttpRequest.open() - user/password not = supported');=0A= }=0A= this.readyState =3D 1;=0A= if (this.onreadystatechange) {=0A= this.onreadystatechange();=0A= }=0A= };=0A= this.send =3D function(data) {=0A= if (!navigator.javaEnabled()) {=0A= alert("XMLHttpRequest.send() - Java must be installed and = enabled.");=0A= return;=0A= }=0A= if (this._async) {=0A= setTimeout(this._sendasync, 0, this, data);=0A= // this is not really asynchronous and won't execute until the = current=0A= // execution context ends=0A= } else {=0A= this._sendsync(data);=0A= }=0A= }=0A= this._sendasync =3D function(req, data) {=0A= if (!req._aborted) {=0A= req._sendsync(data);=0A= }=0A= };=0A= this._sendsync =3D function(data) {=0A= this.readyState =3D 2;=0A= if (this.onreadystatechange) {=0A= this.onreadystatechange();=0A= }=0A= // open connection=0A= var url =3D new java.net.URL(new = java.net.URL(window.location.href), this.url);=0A= var conn =3D url.openConnection();=0A= for (var i =3D 0; i < this._headers.length; i++) {=0A= conn.setRequestProperty(this._headers[i].h, this._headers[i].v);=0A= }=0A= this._headers =3D [];=0A= if (this.method =3D=3D 'POST') {=0A= // POST data=0A= conn.setDoOutput(true);=0A= var wr =3D new = java.io.OutputStreamWriter(conn.getOutputStream(), this._getCharset());=0A= wr.write(data);=0A= wr.flush();=0A= wr.close();=0A= }=0A= // read response headers=0A= // NOTE: the getHeaderField() methods always return nulls for me :(=0A= var gotContentEncoding =3D false;=0A= var gotContentLength =3D false;=0A= var gotContentType =3D false;=0A= var gotDate =3D false;=0A= var gotExpiration =3D false;=0A= var gotLastModified =3D false;=0A= for (var i =3D 0; ; i++) {=0A= var hdrName =3D conn.getHeaderFieldKey(i);=0A= var hdrValue =3D conn.getHeaderField(i);=0A= if (hdrName =3D=3D null && hdrValue =3D=3D null) {=0A= break;=0A= }=0A= if (hdrName !=3D null) {=0A= this._headers[this._headers.length] =3D {h:hdrName, = v:hdrValue};=0A= switch (hdrName.toLowerCase()) {=0A= case 'content-encoding': gotContentEncoding =3D true; break;=0A= case 'content-length' : gotContentLength =3D true; break;=0A= case 'content-type' : gotContentType =3D true; break;=0A= case 'date' : gotDate =3D true; break;=0A= case 'expires' : gotExpiration =3D true; break;=0A= case 'last-modified' : gotLastModified =3D true; break;=0A= }=0A= }=0A= }=0A= // try to fill in any missing header information=0A= var val;=0A= val =3D conn.getContentEncoding();=0A= if (val !=3D null && !gotContentEncoding) = this._headers[this._headers.length] =3D {h:'Content-encoding', v:val};=0A= val =3D conn.getContentLength();=0A= if (val !=3D -1 && !gotContentLength) = this._headers[this._headers.length] =3D {h:'Content-length', v:val};=0A= val =3D conn.getContentType();=0A= if (val !=3D null && !gotContentType) = this._headers[this._headers.length] =3D {h:'Content-type', v:val};=0A= val =3D conn.getDate();=0A= if (val !=3D 0 && !gotDate) this._headers[this._headers.length] = =3D {h:'Date', v:(new Date(val)).toUTCString()};=0A= val =3D conn.getExpiration();=0A= if (val !=3D 0 && !gotExpiration) = this._headers[this._headers.length] =3D {h:'Expires', v:(new = Date(val)).toUTCString()};=0A= val =3D conn.getLastModified();=0A= if (val !=3D 0 && !gotLastModified) = this._headers[this._headers.length] =3D {h:'Last-modified', v:(new = Date(val)).toUTCString()};=0A= // read response data=0A= var reqdata =3D '';=0A= var stream =3D conn.getInputStream();=0A= if (stream) {=0A= var reader =3D new java.io.BufferedReader(new = java.io.InputStreamReader(stream, this._getCharset()));=0A= var line;=0A= while ((line =3D reader.readLine()) !=3D null) {=0A= if (this.readyState =3D=3D 2) {=0A= this.readyState =3D 3;=0A= if (this.onreadystatechange) {=0A= this.onreadystatechange();=0A= }=0A= }=0A= reqdata +=3D line + '\n';=0A= }=0A= reader.close();=0A= this.status =3D 200;=0A= this.statusText =3D 'OK';=0A= this.responseText =3D reqdata;=0A= this.readyState =3D 4;=0A= if (this.onreadystatechange) {=0A= this.onreadystatechange();=0A= }=0A= if (this.onload) {=0A= this.onload();=0A= }=0A= } else {=0A= // error=0A= this.status =3D 404;=0A= this.statusText =3D 'Not Found';=0A= this.responseText =3D '';=0A= this.readyState =3D 4;=0A= if (this.onreadystatechange) {=0A= this.onreadystatechange();=0A= }=0A= if (this.onerror) {=0A= this.onerror();=0A= }=0A= }=0A= };=0A= };=0A= }=0A= // ActiveXObject emulation=0A= if (!window.ActiveXObject && window.XMLHttpRequest) {=0A= window.ActiveXObject =3D function(type) {=0A= switch (type.toLowerCase()) {=0A= case 'microsoft.xmlhttp':=0A= case 'msxml2.xmlhttp':=0A= case 'msxml2.xmlhttp.3.0':=0A= case 'msxml2.xmlhttp.4.0':=0A= case 'msxml2.xmlhttp.5.0':=0A= return new XMLHttpRequest();=0A= }=0A= return null;=0A= };=0A= }=0A= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.jneurosci.org/javascript/ajax/utility.js /************************************************************************= *****=0A= * javascript/ajax/utility.js=0A= *=0A= * Utility functions for working with XMLHttpRequest data.=0A= *=0A= * Copyright 2006 Board of Trustees of the Leland Stanford Junior = University.=0A= = *************************************************************************= ***/=0A= =0A= /*=0A= * Copy XML nodes into an HTMLElement. This effectively=0A= * clones XML markup which uses XHTML naming conventions=0A= * into an HTML DOM.=0A= */=0A= function copy_xml_to_html(src, dst) {=0A= if (src.nodeType =3D=3D 1) { /* Node.ELEMENT_NODE */=0A= var e =3D document.createElement(src.nodeName);=0A= for (var i =3D 0; i < src.childNodes.length; i++) {=0A= copy_xml_to_html(src.childNodes[i], e);=0A= }=0A= for (var i =3D 0; i < src.attributes.length; i++) {=0A= var n =3D src.attributes[i].name;=0A= var v =3D unescape_xml_string(src.attributes[i].value); =0A= e.setAttribute(n, v);=0A= if (n =3D=3D "class") {=0A= e.className =3D v;=0A= }=0A= else if (n =3D=3D "style") {=0A= set_css_style(v, e, "");=0A= }=0A= }=0A= dst.appendChild(e);=0A= }=0A= else if (src.nodeType =3D=3D 3) { /* Node.TEXT_NODE */=0A= dst.appendChild(document.createTextNode(src.nodeValue));=0A= }=0A= }=0A= =0A= /* =0A= * It is unclear that this is the right thing to be calling=0A= * from copy_xml_to_html, but it appears that Safari decides=0A= * to convert & to the NCR #, and then encodes that=0A= * NCR to &%26%2338;. So, I'm going to treat the DOM Attr=0A= * value as a plain string, and run our XML string input=0A= * through the decoding routine below.=0A= */=0A= function unescape_xml_string(s) {=0A= return s.replace(/'/g, "'")=0A= .replace(/'/g, "'")=0A= .replace(/"/g, "\"")=0A= .replace(/"/g, "\"")=0A= .replace(/>/g, ">")=0A= .replace(/>/g, ">")=0A= .replace(/</g, "<")=0A= .replace(/</g, "<")=0A= .replace(/&/g, "&")=0A= .replace(/&/g, "&");=0A= }=0A= =0A= /*=0A= * Parse set of CSS rules and apply them to an element.=0A= * This is quite horrifying, but I'm unable to determine=0A= * how else to handle this with IE 6. FireFox and other=0A= * sane browsers let you simply set the style attribute=0A= * or use e.style.setProperty(rule, value, priority),=0A= * IE 6 appears to have neither of these capabilities..=0A= */=0A= function set_css_style(css, e, priority) {=0A= var rules =3D css.split(";");=0A= for (var i =3D 0; i < rules.length; i++) {=0A= var nvpair =3D rules[i].split(":");=0A= if (nvpair.length =3D=3D 2) {=0A= try {=0A= var name =3D nvpair[0]; /* style attribute */=0A= var value =3D nvpair[1]; /* attribute value */=0A= =0A= /*=0A= * For each possible style attribute, set the=0A= * appropriate style property in the element.=0A= */=0A= if (name =3D=3D "background") {=0A= e.style.background =3D value;=0A= }=0A= else if (name =3D=3D "background-attachment") {=0A= e.style.backgroundAttachment =3D value;=0A= }=0A= else if (name =3D=3D "background-color") {=0A= e.style.backgroundColor =3D value;=0A= }=0A= else if (name =3D=3D "background-image") {=0A= e.style.backgroundImage =3D value;=0A= }=0A= else if (name =3D=3D "background-position") {=0A= e.style.backgroundPosition =3D value;=0A= }=0A= else if (name =3D=3D "background-position-x") {=0A= e.style.backgroundPositionX =3D value;=0A= }=0A= else if (name =3D=3D "background-position-y") {=0A= e.style.backgroundPositionY =3D value;=0A= }=0A= else if (name =3D=3D "background-repeat") {=0A= e.style.backgroundRepeat =3D value;=0A= }=0A= else if (name =3D=3D "behavior") {=0A= e.style.behavior =3D value;=0A= }=0A= else if (name =3D=3D "border") {=0A= e.style.border =3D value;=0A= }=0A= else if (name =3D=3D "border-bottom") {=0A= e.style.borderBottom =3D value;=0A= }=0A= else if (name =3D=3D "border-bottom-color") {=0A= e.style.borderBottomColor =3D value;=0A= }=0A= else if (name =3D=3D "border-bottom-style") {=0A= e.style.borderBottomStyle =3D value;=0A= }=0A= else if (name =3D=3D "border-bottom-width") {=0A= e.style.borderBottomWidth =3D value;=0A= }=0A= else if (name =3D=3D "border-collapse") {=0A= e.style.borderCollapse =3D value;=0A= }=0A= else if (name =3D=3D "border-color") {=0A= e.style.borderColor =3D value;=0A= }=0A= else if (name =3D=3D "border-left") {=0A= e.style.borderLeft =3D value;=0A= }=0A= else if (name =3D=3D "border-left-color") {=0A= e.style.borderLeftColor =3D value;=0A= }=0A= else if (name =3D=3D "border-left-style") {=0A= e.style.borderLeftStyle =3D value;=0A= }=0A= else if (name =3D=3D "border-left-width") {=0A= e.style.borderLeftWidth =3D value;=0A= }=0A= else if (name =3D=3D "border-right") {=0A= e.style.borderRight =3D value;=0A= }=0A= else if (name =3D=3D "border-right-color") {=0A= e.style.borderRightColor =3D value;=0A= }=0A= else if (name =3D=3D "border-right-style") {=0A= e.style.borderRightStyle =3D value;=0A= }=0A= else if (name =3D=3D "border-right-width") {=0A= e.style.borderRightWidth =3D value;=0A= }=0A= else if (name =3D=3D "border-style") {=0A= e.style.borderStyle =3D value;=0A= }=0A= else if (name =3D=3D "border-top") {=0A= e.style.borderTop =3D value;=0A= }=0A= else if (name =3D=3D "border-top-color") {=0A= e.style.borderTopColor =3D value;=0A= }=0A= else if (name =3D=3D "border-top-style") {=0A= e.style.borderTopStyle =3D value;=0A= }=0A= else if (name =3D=3D "border-top-width") {=0A= e.style.borderTopWidth =3D value;=0A= }=0A= else if (name =3D=3D "border-width") {=0A= e.style.borderWidth =3D value;=0A= }=0A= else if (name =3D=3D "bottom") {=0A= e.style.bottom =3D value;=0A= }=0A= else if (name =3D=3D "clear") {=0A= e.style.clear =3D value;=0A= }=0A= else if (name =3D=3D "clip") {=0A= e.style.clip =3D value;=0A= }=0A= else if (name =3D=3D "color") {=0A= e.style.color =3D value;=0A= }=0A= else if (name =3D=3D "cssText") {=0A= e.style.Sets =3D value;=0A= }=0A= else if (name =3D=3D "cursor") {=0A= e.style.cursor =3D value;=0A= }=0A= else if (name =3D=3D "direction") {=0A= e.style.direction =3D value;=0A= }=0A= else if (name =3D=3D "display") {=0A= e.style.display =3D value;=0A= }=0A= else if (name =3D=3D "font") {=0A= e.style.font =3D value;=0A= }=0A= else if (name =3D=3D "font-family") {=0A= e.style.fontFamily =3D value;=0A= }=0A= else if (name =3D=3D "font-size") {=0A= e.style.fontSize =3D value;=0A= }=0A= else if (name =3D=3D "font-style") {=0A= e.style.fontStyle =3D value;=0A= }=0A= else if (name =3D=3D "font-variant") {=0A= e.style.fontVariant =3D value;=0A= }=0A= else if (name =3D=3D "font-weight") {=0A= e.style.fontWeight =3D value;=0A= }=0A= else if (name =3D=3D "height") {=0A= e.style.height =3D value;=0A= }=0A= else if (name =3D=3D "ime-mode") {=0A= e.style.imeMode =3D value;=0A= }=0A= else if (name =3D=3D "layout-flow") {=0A= e.style.layoutFlow =3D value;=0A= }=0A= else if (name =3D=3D "layout-grid") {=0A= e.style.layoutGrid =3D value;=0A= }=0A= else if (name =3D=3D "layout-grid-char") {=0A= e.style.layoutGridChar =3D value;=0A= }=0A= else if (name =3D=3D "layout-grid-line") {=0A= e.style.layoutGridLine =3D value;=0A= }=0A= else if (name =3D=3D "layout-grid-mode") {=0A= e.style.layoutGridMode =3D value;=0A= }=0A= else if (name =3D=3D "layout-grid-type") {=0A= e.style.layoutGridType =3D value;=0A= }=0A= else if (name =3D=3D "left") {=0A= e.style.left =3D value;=0A= }=0A= else if (name =3D=3D "letter-spacing") {=0A= e.style.letterSpacing =3D value;=0A= }=0A= else if (name =3D=3D "line-break") {=0A= e.style.lineBreak =3D value;=0A= }=0A= else if (name =3D=3D "line-height") {=0A= e.style.lineHeight =3D value;=0A= }=0A= else if (name =3D=3D "list-style") {=0A= e.style.listStyle =3D value;=0A= }=0A= else if (name =3D=3D "list-style-image") {=0A= e.style.listStyleImage =3D value;=0A= }=0A= else if (name =3D=3D "list-style-position") {=0A= e.style.listStylePosition =3D value;=0A= }=0A= else if (name =3D=3D "list-style-type") {=0A= e.style.listStyleType =3D value;=0A= }=0A= else if (name =3D=3D "margin") {=0A= e.style.margin =3D value;=0A= }=0A= else if (name =3D=3D "margin-bottom") {=0A= e.style.marginBottom =3D value;=0A= }=0A= else if (name =3D=3D "margin-left") {=0A= e.style.marginLeft =3D value;=0A= }=0A= else if (name =3D=3D "margin-right") {=0A= e.style.marginRight =3D value;=0A= }=0A= else if (name =3D=3D "margin-top") {=0A= e.style.marginTop =3D value;=0A= }=0A= else if (name =3D=3D "min-height") {=0A= e.style.minHeight =3D value;=0A= }=0A= else if (name =3D=3D "overflow") {=0A= e.style.overflow =3D value;=0A= }=0A= else if (name =3D=3D "overflow-x") {=0A= e.style.overflowX =3D value;=0A= }=0A= else if (name =3D=3D "overflow-y") {=0A= e.style.overflowY =3D value;=0A= }=0A= else if (name =3D=3D "padding") {=0A= e.style.padding =3D value;=0A= }=0A= else if (name =3D=3D "padding-bottom") {=0A= e.style.paddingBottom =3D value;=0A= }=0A= else if (name =3D=3D "padding-left") {=0A= e.style.paddingLeft =3D value;=0A= }=0A= else if (name =3D=3D "padding-right") {=0A= e.style.paddingRight =3D value;=0A= }=0A= else if (name =3D=3D "padding-top") {=0A= e.style.paddingTop =3D value;=0A= }=0A= else if (name =3D=3D "page-break-after") {=0A= e.style.pageBreakAfter =3D value;=0A= }=0A= else if (name =3D=3D "page-break-before") {=0A= e.style.pageBreakBefore =3D value;=0A= }=0A= else if (name =3D=3D "pixelBottom") {=0A= e.style.pixelBottom =3D value;=0A= }=0A= else if (name =3D=3D "pixelHeight") {=0A= e.style.pixelHeight =3D value;=0A= }=0A= else if (name =3D=3D "pixelLeft") {=0A= e.style.pixelLeft =3D value;=0A= }=0A= else if (name =3D=3D "pixelRight") {=0A= e.style.pixelRight =3D value;=0A= }=0A= else if (name =3D=3D "pixelTop") {=0A= e.style.pixelTop =3D value;=0A= }=0A= else if (name =3D=3D "pixelWidth") {=0A= e.style.pixelWidth =3D value;=0A= }=0A= else if (name =3D=3D "posBottom") {=0A= e.style.posBottom =3D value;=0A= }=0A= else if (name =3D=3D "posHeight") {=0A= e.style.posHeight =3D value;=0A= }=0A= else if (name =3D=3D "position") {=0A= e.style.position =3D value;=0A= }=0A= else if (name =3D=3D "posLeft") {=0A= e.style.posLeft =3D value;=0A= }=0A= else if (name =3D=3D "posRight") {=0A= e.style.posRight =3D value;=0A= }=0A= else if (name =3D=3D "posTop") {=0A= e.style.posTop =3D value;=0A= }=0A= else if (name =3D=3D "posWidth") {=0A= e.style.posWidth =3D value;=0A= }=0A= else if (name =3D=3D "right") {=0A= e.style.right =3D value;=0A= }=0A= else if (name =3D=3D "ruby-align") {=0A= e.style.rubyAlign =3D value;=0A= }=0A= else if (name =3D=3D "ruby-overhang") {=0A= e.style.rubyOverhang =3D value;=0A= }=0A= else if (name =3D=3D "ruby-position") {=0A= e.style.rubyPosition =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-3dlight-color") {=0A= e.style.scrollbar3dLightColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-arrow-color") {=0A= e.style.scrollbarArrowColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-base-color") {=0A= e.style.scrollbarBaseColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-darkshadow-color") {=0A= e.style.scrollbarDarkShadowColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-face-color") {=0A= e.style.scrollbarFaceColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-highlight-color") {=0A= e.style.scrollbarHighlightColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-shadow-color") {=0A= e.style.scrollbarShadowColor =3D value;=0A= }=0A= else if (name =3D=3D "scrollbar-track-color") {=0A= e.style.scrollbarTrackColor =3D value;=0A= }=0A= else if (name =3D=3D "float") {=0A= e.style.styleFloat =3D value;=0A= }=0A= else if (name =3D=3D "table-layout") {=0A= e.style.tableLayout =3D value;=0A= }=0A= else if (name =3D=3D "text-align") {=0A= e.style.textAlign =3D value;=0A= }=0A= else if (name =3D=3D "text-align-last") {=0A= e.style.textAlignLast =3D value;=0A= }=0A= else if (name =3D=3D "text-autospace") {=0A= e.style.textAutospace =3D value;=0A= }=0A= else if (name =3D=3D "text-decoration") {=0A= e.style.textDecoration =3D value;=0A= }=0A= else if (name =3D=3D "textDecorationBlink") {=0A= e.style.textDecorationBlink =3D value;=0A= }=0A= else if (name =3D=3D "textDecorationLineThrough") {=0A= e.style.textDecorationLineThrough =3D value;=0A= }=0A= else if (name =3D=3D "textDecorationNone") {=0A= e.style.textDecorationNone =3D value;=0A= }=0A= else if (name =3D=3D "textDecorationOverline") {=0A= e.style.textDecorationOverline =3D value;=0A= }=0A= else if (name =3D=3D "textDecorationUnderline") {=0A= e.style.textDecorationUnderline =3D value;=0A= }=0A= else if (name =3D=3D "text-indent") {=0A= e.style.textIndent =3D value;=0A= }=0A= else if (name =3D=3D "text-justify") {=0A= e.style.textJustify =3D value;=0A= }=0A= else if (name =3D=3D "text-kashida-space") {=0A= e.style.textKashidaSpace =3D value;=0A= }=0A= else if (name =3D=3D "text-overflow") {=0A= e.style.textOverflow =3D value;=0A= }=0A= else if (name =3D=3D "text-transform") {=0A= e.style.textTransform =3D value;=0A= }=0A= else if (name =3D=3D "text-underline-position") {=0A= e.style.textUnderlinePosition =3D value;=0A= }=0A= else if (name =3D=3D "top") {=0A= e.style.top =3D value;=0A= }=0A= else if (name =3D=3D "unicode-bidi") {=0A= e.style.unicodeBidi =3D value;=0A= }=0A= else if (name =3D=3D "vertical-align") {=0A= e.style.verticalAlign =3D value;=0A= }=0A= else if (name =3D=3D "visibility") {=0A= e.style.visibility =3D value;=0A= }=0A= else if (name =3D=3D "white-space") {=0A= e.style.whiteSpace =3D value;=0A= }=0A= else if (name =3D=3D "width") {=0A= e.style.width =3D value;=0A= }=0A= else if (name =3D=3D "word-break") {=0A= e.style.wordBreak =3D value;=0A= }=0A= else if (name =3D=3D "word-spacing") {=0A= e.style.wordSpacing =3D value;=0A= }=0A= else if (name =3D=3D "word-wrap") {=0A= e.style.wordWrap =3D value;=0A= }=0A= else if (name =3D=3D "writing-mode") {=0A= e.style.writingMode =3D value;=0A= }=0A= else if (name =3D=3D "z-index") {=0A= e.style.zIndex =3D value;=0A= }=0A= else if (name =3D=3D "zoom") {=0A= e.style.zoom =3D value;=0A= }=0A= }=0A= catch (e) {=0A= /* ignore error on attempt to set e.style.[property] */=0A= }=0A= }=0A= }=0A= }=0A= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.jneurosci.org/javascript/entrez/callback.js /************************************************************************= *****=0A= * javascript/entrez/callback.js=0A= *=0A= * Entrez Linking callback to populate content box.=0A= *=0A= * Copyright 2006 Board of Trustees of the Leland Stanford Junior = University.=0A= = *************************************************************************= ***/=0A= =0A= /*=0A= * Execute callback to fill content box with Entrez Linking information.=0A= */=0A= function entrez_callback(pmid, callback_url) {=0A= /*=0A= * MSIE 5.5 and below have issues with the JavaScript=0A= * used for Entrez Linking. For now we have to disable=0A= * the callback until we can track down a proper fix=0A= * (or everybody sanely upgrades to version 6 or 7!).=0A= */=0A= if (navigator) {=0A= var appname =3D navigator.appName;=0A= if (appname =3D=3D "Microsoft Internet Explorer") {=0A= var userAgent =3D navigator["userAgent"];=0A= var s =3D "MSIE ";=0A= var n =3D -1; =0A= if ((n =3D userAgent.indexOf(s)) !=3D -1) {=0A= var v =3D parseFloat(userAgent.substring(n+s.length));=0A= if (v < 6) {=0A= return;=0A= }=0A= }=0A= }=0A= }=0A= =0A= /*=0A= * Acquire table row element to update, initiate callback=0A= * to update table with Entrez Links.=0A= */=0A= var tr =3D document.getElementById('entrez_callback_'+pmid);=0A= if (!tr) {=0A= return;=0A= }=0A= var req =3D new XMLHttpRequest();=0A= if (!req) {=0A= return;=0A= }=0A= req.onreadystatechange =3D function() {=0A= if (req.readyState =3D=3D 4 && (req.status =3D=3D 200 || req.status = =3D=3D 304)) {=0A= var src =3D req.responseXML.documentElement;=0A= var dst =3D document.createDocumentFragment();=0A= for (var i =3D 0; i < src.childNodes.length; i++) {=0A= copy_xml_to_html(src.childNodes[i], dst);=0A= }=0A= var tbl =3D tr.parentNode;=0A= tbl.replaceChild(dst, tr);=0A= }=0A= }=0A= req.open('GET', callback_url, true);=0A= req.send(null);=0A= }=0A= ------=_NextPart_000_0241_01C85B7B.BC962280 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.google-analytics.com/urchin.js //-- Google Analytics Urchin Module=0A= //-- Copyright 2007 Google, All Rights Reserved.=0A= =0A= //-- Urchin On Demand Settings ONLY=0A= var _uacct=3D""; // set up the Urchin Account=0A= var _userv=3D1; // service mode (0=3Dlocal,1=3Dremote,2=3Dboth)=0A= =0A= //-- UTM User Settings=0A= var _ufsc=3D1; // set client info flag (1=3Don|0=3Doff)=0A= var _udn=3D"auto"; // (auto|none|domain) set the domain name for cookies=0A= var _uhash=3D"on"; // (on|off) unique domain hash for cookies=0A= var _utimeout=3D"1800"; // set the inactive session timeout in seconds=0A= var _ugifpath=3D"/__utm.gif"; // set the web path to the __utm.gif file=0A= var _utsp=3D"|"; // transaction field separator=0A= var _uflash=3D1; // set flash version detect option (1=3Don|0=3Doff)=0A= var _utitle=3D1; // set the document title detect option = (1=3Don|0=3Doff)=0A= var _ulink=3D0; // enable linker functionality (1=3Don|0=3Doff)=0A= var _uanchor=3D0; // enable use of anchors for campaign = (1=3Don|0=3Doff)=0A= var _utcp=3D"/"; // the cookie path for tracking=0A= var _usample=3D100; // The sampling % of visitors to track (1-100).=0A= =0A= //-- UTM Campaign Tracking Settings=0A= var _uctm=3D1; // set campaign tracking module (1=3Don|0=3Doff)=0A= var _ucto=3D"15768000"; // set timeout in seconds (6 month default)=0A= var _uccn=3D"utm_campaign"; // name=0A= var _ucmd=3D"utm_medium"; // medium (cpc|cpm|link|email|organic)=0A= var _ucsr=3D"utm_source"; // source=0A= var _uctr=3D"utm_term"; // term/keyword=0A= var _ucct=3D"utm_content"; // content=0A= var _ucid=3D"utm_id"; // id number=0A= var _ucno=3D"utm_nooverride"; // don't override=0A= =0A= //-- Auto/Organic Sources and Keywords=0A= var _uOsr=3Dnew Array();=0A= var _uOkw=3Dnew Array();=0A= _uOsr[0]=3D"google"; _uOkw[0]=3D"q";=0A= _uOsr[1]=3D"yahoo"; _uOkw[1]=3D"p";=0A= _uOsr[2]=3D"msn"; _uOkw[2]=3D"q";=0A= _uOsr[3]=3D"aol"; _uOkw[3]=3D"query";=0A= _uOsr[4]=3D"aol"; _uOkw[4]=3D"encquery";=0A= _uOsr[5]=3D"lycos"; _uOkw[5]=3D"query";=0A= _uOsr[6]=3D"ask"; _uOkw[6]=3D"q";=0A= _uOsr[7]=3D"altavista"; _uOkw[7]=3D"q";=0A= _uOsr[8]=3D"netscape"; _uOkw[8]=3D"query";=0A= _uOsr[9]=3D"cnn"; _uOkw[9]=3D"query";=0A= _uOsr[10]=3D"looksmart"; _uOkw[10]=3D"qt";=0A= _uOsr[11]=3D"about"; _uOkw[11]=3D"terms";=0A= _uOsr[12]=3D"mamma"; _uOkw[12]=3D"query";=0A= _uOsr[13]=3D"alltheweb"; _uOkw[13]=3D"q";=0A= _uOsr[14]=3D"gigablast"; _uOkw[14]=3D"q";=0A= _uOsr[15]=3D"voila"; _uOkw[15]=3D"rdata";=0A= _uOsr[16]=3D"virgilio"; _uOkw[16]=3D"qs";=0A= _uOsr[17]=3D"live"; _uOkw[17]=3D"q";=0A= _uOsr[18]=3D"baidu"; _uOkw[18]=3D"wd";=0A= _uOsr[19]=3D"alice"; _uOkw[19]=3D"qs";=0A= _uOsr[20]=3D"yandex"; _uOkw[20]=3D"text";=0A= _uOsr[21]=3D"najdi"; _uOkw[21]=3D"q";=0A= _uOsr[22]=3D"aol"; _uOkw[22]=3D"q";=0A= _uOsr[23]=3D"club-internet"; _uOkw[23]=3D"q";=0A= _uOsr[24]=3D"mama"; _uOkw[24]=3D"query";=0A= _uOsr[25]=3D"seznam"; _uOkw[25]=3D"q";=0A= _uOsr[26]=3D"search"; _uOkw[26]=3D"q";=0A= _uOsr[27]=3D"szukaj"; _uOkw[27]=3D"szukaj";=0A= _uOsr[28]=3D"szukaj"; _uOkw[28]=3D"qt";=0A= _uOsr[29]=3D"netsprint"; _uOkw[29]=3D"q";=0A= _uOsr[30]=3D"google.interia"; _uOkw[30]=3D"q";=0A= _uOsr[31]=3D"szukacz"; _uOkw[31]=3D"q";=0A= _uOsr[32]=3D"yam"; _uOkw[32]=3D"k";=0A= _uOsr[33]=3D"pchome"; _uOkw[33]=3D"q";=0A= =0A= =0A= //-- Auto/Organic Keywords to Ignore=0A= var _uOno=3Dnew Array();=0A= //_uOno[0]=3D"urchin";=0A= //_uOno[1]=3D"urchin.com";=0A= //_uOno[2]=3D"www.urchin.com";=0A= =0A= //-- Referral domains to Ignore=0A= var _uRno=3Dnew Array();=0A= //_uRno[0]=3D".urchin.com";=0A= =0A= //-- **** Don't modify below this point ***=0A= var = _uff,_udh,_udt,_ubl=3D0,_udo=3D"",_uu,_ufns=3D0,_uns=3D0,_ur=3D"-",_ufno=3D= 0,_ust=3D0,_ubd=3Ddocument,_udl=3D_ubd.location,_udlh=3D"",_uwv=3D"1";=0A= var _ugifpath2=3D"http://www.google-analytics.com/__utm.gif";=0A= if (_udl.hash) _udlh=3D_udl.href.substring(_udl.href.indexOf('#'));=0A= if (_udl.protocol=3D=3D"https:") = _ugifpath2=3D"https://ssl.google-analytics.com/__utm.gif";=0A= if (!_utcp || _utcp=3D=3D"") _utcp=3D"/";=0A= function urchinTracker(page) {=0A= if (_udl.protocol=3D=3D"file:") return;=0A= if (_uff && (!page || page=3D=3D"")) return;=0A= var a,b,c,xx,v,z,k,x=3D"",s=3D"",f=3D0;=0A= var nx=3D" expires=3D"+_uNx()+";";=0A= var dc=3D_ubd.cookie;=0A= _udh=3D_uDomain();=0A= if (!_uVG()) return;=0A= _uu=3DMath.round(Math.random()*2147483647);=0A= _udt=3Dnew Date();=0A= _ust=3DMath.round(_udt.getTime()/1000);=0A= a=3Ddc.indexOf("__utma=3D"+_udh);=0A= b=3Ddc.indexOf("__utmb=3D"+_udh);=0A= c=3Ddc.indexOf("__utmc=3D"+_udh);=0A= if (_udn && _udn!=3D"") { _udo=3D" domain=3D"+_udn+";"; }=0A= if (_utimeout && _utimeout!=3D"") {=0A= x=3Dnew Date(_udt.getTime()+(_utimeout*1000));=0A= x=3D" expires=3D"+x.toGMTString()+";";=0A= }=0A= if (_ulink) {=0A= if (_uanchor && _udlh && _udlh!=3D"") s=3D_udlh+"&";=0A= s+=3D_udl.search;=0A= if(s && s!=3D"" && s.indexOf("__utma=3D")>=3D0) {=0A= if (!(_uIN(a=3D_uGC(s,"__utma=3D","&")))) a=3D"-";=0A= if (!(_uIN(b=3D_uGC(s,"__utmb=3D","&")))) b=3D"-";=0A= if (!(_uIN(c=3D_uGC(s,"__utmc=3D","&")))) c=3D"-";=0A= v=3D_uGC(s,"__utmv=3D","&");=0A= z=3D_uGC(s,"__utmz=3D","&");=0A= k=3D_uGC(s,"__utmk=3D","&");=0A= xx=3D_uGC(s,"__utmx=3D","&");=0A= if ((k*1) !=3D ((_uHash(a+b+c+xx+z+v)*1)+(_udh*1))) = {_ubl=3D1;a=3D"-";b=3D"-";c=3D"-";xx=3D"-";z=3D"-";v=3D"-";}=0A= if (a!=3D"-" && b!=3D"-" && c!=3D"-") f=3D1;=0A= else if(a!=3D"-") f=3D2;=0A= }=0A= }=0A= if(f=3D=3D1) {=0A= _ubd.cookie=3D"__utma=3D"+a+"; path=3D"+_utcp+";"+nx+_udo;=0A= _ubd.cookie=3D"__utmb=3D"+b+"; path=3D"+_utcp+";"+x+_udo;=0A= _ubd.cookie=3D"__utmc=3D"+c+"; path=3D"+_utcp+";"+_udo;=0A= } else if (f=3D=3D2) {=0A= a=3D_uFixA(s,"&",_ust);=0A= _ubd.cookie=3D"__utma=3D"+a+"; path=3D"+_utcp+";"+nx+_udo;=0A= _ubd.cookie=3D"__utmb=3D"+_udh+"; path=3D"+_utcp+";"+x+_udo;=0A= _ubd.cookie=3D"__utmc=3D"+_udh+"; path=3D"+_utcp+";"+_udo;=0A= _ufns=3D1;=0A= } else if (a>=3D0 && b>=3D0 && c>=3D0) {=0A= _ubd.cookie=3D"__utmb=3D"+_udh+"; path=3D"+_utcp+";"+x+_udo;=0A= } else {=0A= if (a>=3D0) a=3D_uFixA(_ubd.cookie,";",_ust);=0A= else a=3D_udh+"."+_uu+"."+_ust+"."+_ust+"."+_ust+".1";=0A= _ubd.cookie=3D"__utma=3D"+a+"; path=3D"+_utcp+";"+nx+_udo;=0A= _ubd.cookie=3D"__utmb=3D"+_udh+"; path=3D"+_utcp+";"+x+_udo;=0A= _ubd.cookie=3D"__utmc=3D"+_udh+"; path=3D"+_utcp+";"+_udo;=0A= _ufns=3D1;=0A= }=0A= if (_ulink && xx && xx!=3D"" && xx!=3D"-") {=0A= xx=3D_uUES(xx);=0A= if (xx.indexOf(";")=3D=3D-1) _ubd.cookie=3D"__utmx=3D"+xx+"; = path=3D"+_utcp+";"+nx+_udo;=0A= }=0A= if (_ulink && v && v!=3D"" && v!=3D"-") {=0A= v=3D_uUES(v);=0A= if (v.indexOf(";")=3D=3D-1) _ubd.cookie=3D"__utmv=3D"+v+"; = path=3D"+_utcp+";"+nx+_udo;=0A= }=0A= _uInfo(page);=0A= _ufns=3D0;=0A= _ufno=3D0;=0A= if (!page || page=3D=3D"") _uff=3D1;=0A= }=0A= function _uInfo(page) {=0A= var p,s=3D"",dm=3D"",pg=3D_udl.pathname+_udl.search;=0A= if (page && page!=3D"") pg=3D_uES(page,1);=0A= _ur=3D_ubd.referrer;=0A= if (!_ur || _ur=3D=3D"") { _ur=3D"-"; }=0A= else {=0A= dm=3D_ubd.domain;=0A= if(_utcp && _utcp!=3D"/") dm+=3D_utcp;=0A= p=3D_ur.indexOf(dm);=0A= if ((p>=3D0) && (p<=3D8)) { _ur=3D"0"; }=0A= if (_ur.indexOf("[")=3D=3D0 && = _ur.lastIndexOf("]")=3D=3D(_ur.length-1)) { _ur=3D"-"; }=0A= }=0A= s+=3D"&utmn=3D"+_uu;=0A= if (_ufsc) s+=3D_uBInfo();=0A= if (_uctm) s+=3D_uCInfo();=0A= if (_utitle && _ubd.title && _ubd.title!=3D"") = s+=3D"&utmdt=3D"+_uES(_ubd.title);=0A= if (_udl.hostname && _udl.hostname!=3D"") = s+=3D"&utmhn=3D"+_uES(_udl.hostname);=0A= s+=3D"&utmr=3D"+_ur;=0A= s+=3D"&utmp=3D"+pg;=0A= if ((_userv=3D=3D0 || _userv=3D=3D2) && _uSP()) {=0A= var i=3Dnew Image(1,1);=0A= i.src=3D_ugifpath+"?"+"utmwv=3D"+_uwv+s;=0A= i.onload=3Dfunction() {_uVoid();}=0A= }=0A= if ((_userv=3D=3D1 || _userv=3D=3D2) && _uSP()) {=0A= var i2=3Dnew Image(1,1);=0A= = i2.src=3D_ugifpath2+"?"+"utmwv=3D"+_uwv+s+"&utmac=3D"+_uacct+"&utmcc=3D"+= _uGCS();=0A= i2.onload=3Dfunction() { _uVoid(); }=0A= }=0A= return;=0A= }=0A= function _uVoid() { return; }=0A= function _uCInfo() {=0A= if (!_ucto || _ucto=3D=3D"") { _ucto=3D"15768000"; }=0A= if (!_uVG()) return;=0A= var = c=3D"",t=3D"-",t2=3D"-",t3=3D"-",o=3D0,cs=3D0,cn=3D0,i=3D0,z=3D"-",s=3D""= ;=0A= if (_uanchor && _udlh && _udlh!=3D"") s=3D_udlh+"&";=0A= s+=3D_udl.search;=0A= var x=3Dnew Date(_udt.getTime()+(_ucto*1000));=0A= var dc=3D_ubd.cookie;=0A= x=3D" expires=3D"+x.toGMTString()+";";=0A= if (_ulink && !_ubl) {=0A= z=3D_uUES(_uGC(s,"__utmz=3D","&"));=0A= if (z!=3D"-" && z.indexOf(";")=3D=3D-1) { = _ubd.cookie=3D"__utmz=3D"+z+"; path=3D"+_utcp+";"+x+_udo; return ""; }=0A= }=0A= z=3Ddc.indexOf("__utmz=3D"+_udh);=0A= if (z>-1) { z=3D_uGC(dc,"__utmz=3D"+_udh,";"); }=0A= else { z=3D"-"; }=0A= t=3D_uGC(s,_ucid+"=3D","&");=0A= t2=3D_uGC(s,_ucsr+"=3D","&");=0A= t3=3D_uGC(s,"gclid=3D","&");=0A= if ((t!=3D"-" && t!=3D"") || (t2!=3D"-" && t2!=3D"") || (t3!=3D"-" && = t3!=3D"")) {=0A= if (t!=3D"-" && t!=3D"") c+=3D"utmcid=3D"+_uEC(t);=0A= if (t2!=3D"-" && t2!=3D"") { if (c !=3D "") c+=3D"|"; = c+=3D"utmcsr=3D"+_uEC(t2); }=0A= if (t3!=3D"-" && t3!=3D"") { if (c !=3D "") c+=3D"|"; = c+=3D"utmgclid=3D"+_uEC(t3); }=0A= t=3D_uGC(s,_uccn+"=3D","&");=0A= if (t!=3D"-" && t!=3D"") c+=3D"|utmccn=3D"+_uEC(t);=0A= else c+=3D"|utmccn=3D(not+set)";=0A= t=3D_uGC(s,_ucmd+"=3D","&");=0A= if (t!=3D"-" && t!=3D"") c+=3D"|utmcmd=3D"+_uEC(t);=0A= else c+=3D"|utmcmd=3D(not+set)";=0A= t=3D_uGC(s,_uctr+"=3D","&");=0A= if (t!=3D"-" && t!=3D"") c+=3D"|utmctr=3D"+_uEC(t);=0A= else { t=3D_uOrg(1); if (t!=3D"-" && t!=3D"") = c+=3D"|utmctr=3D"+_uEC(t); }=0A= t=3D_uGC(s,_ucct+"=3D","&");=0A= if (t!=3D"-" && t!=3D"") c+=3D"|utmcct=3D"+_uEC(t);=0A= t=3D_uGC(s,_ucno+"=3D","&");=0A= if (t=3D=3D"1") o=3D1;=0A= if (z!=3D"-" && o=3D=3D1) return "";=0A= }=0A= if (c=3D=3D"-" || c=3D=3D"") { c=3D_uOrg(); if (z!=3D"-" && = _ufno=3D=3D1) return ""; }=0A= if (c=3D=3D"-" || c=3D=3D"") { if (_ufns=3D=3D1) c=3D_uRef(); if = (z!=3D"-" && _ufno=3D=3D1) return ""; }=0A= if (c=3D=3D"-" || c=3D=3D"") {=0A= if (z=3D=3D"-" && _ufns=3D=3D1) { = c=3D"utmccn=3D(direct)|utmcsr=3D(direct)|utmcmd=3D(none)"; }=0A= if (c=3D=3D"-" || c=3D=3D"") return "";=0A= }=0A= if (z!=3D"-") {=0A= i=3Dz.indexOf(".");=0A= if (i>-1) i=3Dz.indexOf(".",i+1);=0A= if (i>-1) i=3Dz.indexOf(".",i+1);=0A= if (i>-1) i=3Dz.indexOf(".",i+1);=0A= t=3Dz.substring(i+1,z.length);=0A= if (t.toLowerCase()=3D=3Dc.toLowerCase()) cs=3D1;=0A= t=3Dz.substring(0,i);=0A= if ((i=3Dt.lastIndexOf(".")) > -1) {=0A= t=3Dt.substring(i+1,t.length);=0A= cn=3D(t*1);=0A= }=0A= }=0A= if (cs=3D=3D0 || _ufns=3D=3D1) {=0A= t=3D_uGC(dc,"__utma=3D"+_udh,";");=0A= if ((i=3Dt.lastIndexOf(".")) > 9) {=0A= _uns=3Dt.substring(i+1,t.length);=0A= _uns=3D(_uns*1);=0A= }=0A= cn++;=0A= if (_uns=3D=3D0) _uns=3D1;=0A= _ubd.cookie=3D"__utmz=3D"+_udh+"."+_ust+"."+_uns+"."+cn+"."+c+"; = path=3D"+_utcp+"; "+x+_udo;=0A= }=0A= if (cs=3D=3D0 || _ufns=3D=3D1) return "&utmcn=3D1";=0A= else return "&utmcr=3D1";=0A= }=0A= function _uRef() {=0A= if (_ur=3D=3D"0" || _ur=3D=3D"" || _ur=3D=3D"-") return "";=0A= var i=3D0,h,k,n;=0A= if ((i=3D_ur.indexOf("://"))<0) return "";=0A= h=3D_ur.substring(i+3,_ur.length);=0A= if (h.indexOf("/") > -1) {=0A= k=3Dh.substring(h.indexOf("/"),h.length);=0A= if (k.indexOf("?") > -1) k=3Dk.substring(0,k.indexOf("?"));=0A= h=3Dh.substring(0,h.indexOf("/"));=0A= }=0A= h=3Dh.toLowerCase();=0A= n=3Dh;=0A= if ((i=3Dn.indexOf(":")) > -1) n=3Dn.substring(0,i);=0A= for (var ii=3D0;ii<_uRno.length;ii++) {=0A= if ((i=3Dn.indexOf(_uRno[ii].toLowerCase())) > -1 && = n.length=3D=3D(i+_uRno[ii].length)) { _ufno=3D1; break; }=0A= }=0A= if (h.indexOf("www.")=3D=3D0) h=3Dh.substring(4,h.length);=0A= return = "utmccn=3D(referral)|utmcsr=3D"+_uEC(h)+"|"+"utmcct=3D"+_uEC(k)+"|utmcmd=3D= referral";=0A= }=0A= function _uOrg(t) {=0A= if (_ur=3D=3D"0" || _ur=3D=3D"" || _ur=3D=3D"-") return "";=0A= var i=3D0,h,k;=0A= if ((i=3D_ur.indexOf("://")) < 0) return "";=0A= h=3D_ur.substring(i+3,_ur.length);=0A= if (h.indexOf("/") > -1) {=0A= h=3Dh.substring(0,h.indexOf("/"));=0A= }=0A= for (var ii=3D0;ii<_uOsr.length;ii++) {=0A= if (h.toLowerCase().indexOf(_uOsr[ii].toLowerCase()) > -1) {=0A= if ((i=3D_ur.indexOf("?"+_uOkw[ii]+"=3D")) > -1 || = (i=3D_ur.indexOf("&"+_uOkw[ii]+"=3D")) > -1) {=0A= k=3D_ur.substring(i+_uOkw[ii].length+2,_ur.length);=0A= if ((i=3Dk.indexOf("&")) > -1) k=3Dk.substring(0,i);=0A= for (var yy=3D0;yy<_uOno.length;yy++) {=0A= if (_uOno[yy].toLowerCase()=3D=3Dk.toLowerCase()) { _ufno=3D1; = break; }=0A= }=0A= if (t) return _uEC(k);=0A= else return = "utmccn=3D(organic)|utmcsr=3D"+_uEC(_uOsr[ii])+"|"+"utmctr=3D"+_uEC(k)+"|= utmcmd=3Dorganic";=0A= }=0A= }=0A= }=0A= return "";=0A= }=0A= function _uBInfo() {=0A= var sr=3D"-",sc=3D"-",ul=3D"-",fl=3D"-",cs=3D"-",je=3D1;=0A= var n=3Dnavigator;=0A= if (self.screen) {=0A= sr=3Dscreen.width+"x"+screen.height;=0A= sc=3Dscreen.colorDepth+"-bit";=0A= } else if (self.java) {=0A= var j=3Djava.awt.Toolkit.getDefaultToolkit();=0A= var s=3Dj.getScreenSize();=0A= sr=3Ds.width+"x"+s.height;=0A= }=0A= if (n.language) { ul=3Dn.language.toLowerCase(); }=0A= else if (n.browserLanguage) { ul=3Dn.browserLanguage.toLowerCase(); }=0A= je=3Dn.javaEnabled()?1:0;=0A= if (_uflash) fl=3D_uFlash();=0A= if (_ubd.characterSet) cs=3D_uES(_ubd.characterSet);=0A= else if (_ubd.charset) cs=3D_uES(_ubd.charset);=0A= return = "&utmcs=3D"+cs+"&utmsr=3D"+sr+"&utmsc=3D"+sc+"&utmul=3D"+ul+"&utmje=3D"+j= e+"&utmfl=3D"+fl;=0A= }=0A= function __utmSetTrans() {=0A= var e;=0A= if (_ubd.getElementById) e=3D_ubd.getElementById("utmtrans");=0A= else if (_ubd.utmform && _ubd.utmform.utmtrans) = e=3D_ubd.utmform.utmtrans;=0A= if (!e) return;=0A= var l=3De.value.split("UTM:");=0A= var i,i2,c;=0A= if (_userv=3D=3D0 || _userv=3D=3D2) i=3Dnew Array();=0A= if (_userv=3D=3D1 || _userv=3D=3D2) { i2=3Dnew Array(); c=3D_uGCS(); }=0A= =0A= for (var ii=3D0;ii=3D2;ii--) {=0A= try {=0A= var fl=3Deval("new = ActiveXObject('ShockwaveFlash.ShockwaveFlash."+ii+"');");=0A= if (fl) { f=3Dii + '.0'; break; }=0A= }=0A= catch(e) {}=0A= }=0A= }=0A= return f;=0A= }=0A= function __utmLinker(l,h) {=0A= if (!_ulink) return;=0A= var p,k,a=3D"-",b=3D"-",c=3D"-",x=3D"-",z=3D"-",v=3D"-";=0A= var dc=3D_ubd.cookie;=0A= if (!l || l=3D=3D"") return;=0A= var iq =3D l.indexOf("?"); =0A= var ih =3D l.indexOf("#"); =0A= if (dc) {=0A= a=3D_uES(_uGC(dc,"__utma=3D"+_udh,";"));=0A= b=3D_uES(_uGC(dc,"__utmb=3D"+_udh,";"));=0A= c=3D_uES(_uGC(dc,"__utmc=3D"+_udh,";"));=0A= x=3D_uES(_uGC(dc,"__utmx=3D"+_udh,";"));=0A= z=3D_uES(_uGC(dc,"__utmz=3D"+_udh,";"));=0A= v=3D_uES(_uGC(dc,"__utmv=3D"+_udh,";"));=0A= k=3D(_uHash(a+b+c+x+z+v)*1)+(_udh*1);=0A= = p=3D"__utma=3D"+a+"&__utmb=3D"+b+"&__utmc=3D"+c+"&__utmx=3D"+x+"&__utmz=3D= "+z+"&__utmv=3D"+v+"&__utmk=3D"+k;=0A= }=0A= if (p) {=0A= if (h && ih>-1) return;=0A= if (h) { _udl.href=3Dl+"#"+p; }=0A= else {=0A= if (iq=3D=3D-1 && ih=3D=3D-1) _udl.href=3Dl+"?"+p;=0A= else if (ih=3D=3D-1) _udl.href=3Dl+"&"+p;=0A= else if (iq=3D=3D-1) = _udl.href=3Dl.substring(0,ih-1)+"?"+p+l.substring(ih);=0A= else _udl.href=3Dl.substring(0,ih-1)+"&"+p+l.substring(ih);=0A= }=0A= } else { _udl.href=3Dl; }=0A= }=0A= function __utmLinkPost(f,h) {=0A= if (!_ulink) return;=0A= var p,k,a=3D"-",b=3D"-",c=3D"-",x=3D"-",z=3D"-",v=3D"-";=0A= var dc=3D_ubd.cookie;=0A= if (!f || !f.action) return;=0A= var iq =3D f.action.indexOf("?"); =0A= var ih =3D f.action.indexOf("#"); =0A= if (dc) {=0A= a=3D_uES(_uGC(dc,"__utma=3D"+_udh,";"));=0A= b=3D_uES(_uGC(dc,"__utmb=3D"+_udh,";"));=0A= c=3D_uES(_uGC(dc,"__utmc=3D"+_udh,";"));=0A= x=3D_uES(_uGC(dc,"__utmx=3D"+_udh,";"));=0A= z=3D_uES(_uGC(dc,"__utmz=3D"+_udh,";"));=0A= v=3D_uES(_uGC(dc,"__utmv=3D"+_udh,";"));=0A= k=3D(_uHash(a+b+c+x+z+v)*1)+(_udh*1);=0A= = p=3D"__utma=3D"+a+"&__utmb=3D"+b+"&__utmc=3D"+c+"&__utmx=3D"+x+"&__utmz=3D= "+z+"&__utmv=3D"+v+"&__utmk=3D"+k;=0A= }=0A= if (p) {=0A= if (h && ih>-1) return;=0A= if (h) { f.action+=3D"#"+p; }=0A= else {=0A= if (iq=3D=3D-1 && ih=3D=3D-1) f.action+=3D"?"+p;=0A= else if (ih=3D=3D-1) f.action+=3D"&"+p;=0A= else if (iq=3D=3D-1) = f.action=3Df.action.substring(0,ih-1)+"?"+p+f.action.substring(ih);=0A= else = f.action=3Df.action.substring(0,ih-1)+"&"+p+f.action.substring(ih);=0A= }=0A= }=0A= return;=0A= }=0A= function __utmSetVar(v) {=0A= if (!v || v=3D=3D"") return;=0A= if (!_udo || _udo =3D=3D "") {=0A= _udh=3D_uDomain();=0A= if (_udn && _udn!=3D"") { _udo=3D" domain=3D"+_udn+";"; }=0A= }=0A= if (!_uVG()) return;=0A= var r=3DMath.round(Math.random() * 2147483647);=0A= _ubd.cookie=3D"__utmv=3D"+_udh+"."+_uES(v)+"; path=3D"+_utcp+"; = expires=3D"+_uNx()+";"+_udo;=0A= var s=3D"&utmt=3Dvar&utmn=3D"+r;=0A= if ((_userv=3D=3D0 || _userv=3D=3D2) && _uSP()) {=0A= var i=3Dnew Image(1,1);=0A= i.src=3D_ugifpath+"?"+"utmwv=3D"+_uwv+s;=0A= i.onload=3Dfunction() { _uVoid(); }=0A= }=0A= if ((_userv=3D=3D1 || _userv=3D=3D2) && _uSP()) {=0A= var i2=3Dnew Image(1,1);=0A= = i2.src=3D_ugifpath2+"?"+"utmwv=3D"+_uwv+s+"&utmac=3D"+_uacct+"&utmcc=3D"+= _uGCS();=0A= i2.onload=3Dfunction() { _uVoid(); }=0A= }=0A= }=0A= function _uGCS() {=0A= var t,c=3D"",dc=3D_ubd.cookie;=0A= if ((t=3D_uGC(dc,"__utma=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utma=3D"+t+";+");=0A= if ((t=3D_uGC(dc,"__utmb=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utmb=3D"+t+";+");=0A= if ((t=3D_uGC(dc,"__utmc=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utmc=3D"+t+";+");=0A= if ((t=3D_uGC(dc,"__utmx=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utmx=3D"+t+";+");=0A= if ((t=3D_uGC(dc,"__utmz=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utmz=3D"+t+";+");=0A= if ((t=3D_uGC(dc,"__utmv=3D"+_udh,";"))!=3D"-") = c+=3D_uES("__utmv=3D"+t+";");=0A= if (c.charAt(c.length-1)=3D=3D"+") c=3Dc.substring(0,c.length-1);=0A= return c;=0A= }=0A= function _uGC(l,n,s) {=0A= if (!l || l=3D=3D"" || !n || n=3D=3D"" || !s || s=3D=3D"") return "-";=0A= var i,i2,i3,c=3D"-";=0A= i=3Dl.indexOf(n);=0A= i3=3Dn.indexOf("=3D")+1;=0A= if (i > -1) {=0A= i2=3Dl.indexOf(s,i); if (i2 < 0) { i2=3Dl.length; }=0A= c=3Dl.substring((i+i3),i2);=0A= }=0A= return c;=0A= }=0A= function _uDomain() {=0A= if (!_udn || _udn=3D=3D"" || _udn=3D=3D"none") { _udn=3D""; return 1; }=0A= if (_udn=3D=3D"auto") {=0A= var d=3D_ubd.domain;=0A= if (d.substring(0,4)=3D=3D"www.") {=0A= d=3Dd.substring(4,d.length);=0A= }=0A= _udn=3Dd;=0A= }=0A= _udn =3D _udn.toLowerCase(); =0A= if (_uhash=3D=3D"off") return 1;=0A= return _uHash(_udn);=0A= }=0A= function _uHash(d) {=0A= if (!d || d=3D=3D"") return 1;=0A= var h=3D0,g=3D0;=0A= for (var i=3Dd.length-1;i>=3D0;i--) {=0A= var c=3DparseInt(d.charCodeAt(i));=0A= h=3D((h << 6) & 0xfffffff) + c + (c << 14);=0A= if ((g=3Dh & 0xfe00000)!=3D0) h=3D(h ^ (g >> 21));=0A= }=0A= return h;=0A= }=0A= function _uFixA(c,s,t) {=0A= if (!c || c=3D=3D"" || !s || s=3D=3D"" || !t || t=3D=3D"") return "-";=0A= var a=3D_uGC(c,"__utma=3D"+_udh,s);=0A= var lt=3D0,i=3D0;=0A= if ((i=3Da.lastIndexOf(".")) > 9) {=0A= _uns=3Da.substring(i+1,a.length);=0A= _uns=3D(_uns*1)+1;=0A= a=3Da.substring(0,i);=0A= if ((i=3Da.lastIndexOf(".")) > 7) {=0A= lt=3Da.substring(i+1,a.length);=0A= a=3Da.substring(0,i);=0A= }=0A= if ((i=3Da.lastIndexOf(".")) > 5) {=0A= a=3Da.substring(0,i);=0A= }=0A= a+=3D"."+lt+"."+t+"."+_uns;=0A= }=0A= return a;=0A= }=0A= function _uTrim(s) {=0A= if (!s || s=3D=3D"") return "";=0A= while ((s.charAt(0)=3D=3D' ') || (s.charAt(0)=3D=3D'\n') || = (s.charAt(0,1)=3D=3D'\r')) s=3Ds.substring(1,s.length);=0A= while ((s.charAt(s.length-1)=3D=3D' ') || = (s.charAt(s.length-1)=3D=3D'\n') || (s.charAt(s.length-1)=3D=3D'\r')) = s=3Ds.substring(0,s.length-1);=0A= return s;=0A= }=0A= function _uEC(s) {=0A= var n=3D"";=0A= if (!s || s=3D=3D"") return "";=0A= for (var i=3D0;i0) r=3Da.substring(i+1,i2); else return = ""; =0A= if ((i=3Da.indexOf(".",i2+1))>0) t=3Da.substring(i2+1,i); else return = ""; =0A= if (f) {=0A= return r;=0A= } else {=0A= var c=3Dnew = Array('A','B','C','D','E','F','G','H','J','K','L','M','N','P','R','S','T'= ,'U','V','W','X','Y','Z','1','2','3','4','5','6','7','8','9');=0A= return = c[r>>28&m]+c[r>>23&m]+c[r>>18&m]+c[r>>13&m]+"-"+c[r>>8&m]+c[r>>3&m]+c[((r= &7)<<2)+(t>>30&3)]+c[t>>25&m]+c[t>>20&m]+"-"+c[t>>15&m]+c[t>>10&m]+c[t>>5= &m]+c[t&m];=0A= }=0A= }=0A= function _uIN(n) {=0A= if (!n) return false;=0A= for (var i=3D0;i"9") && (c!=3D".")) return false;=0A= }=0A= return true;=0A= }=0A= function _uES(s,u) {=0A= if (typeof(encodeURIComponent) =3D=3D 'function') {=0A= if (u) return encodeURI(s);=0A= else return encodeURIComponent(s);=0A= } else {=0A= return escape(s);=0A= }=0A= }=0A= function _uUES(s) {=0A= if (typeof(decodeURIComponent) =3D=3D 'function') {=0A= return decodeURIComponent(s);=0A= } else {=0A= return unescape(s);=0A= }=0A= }=0A= function _uVG() {=0A= if((_udn.indexOf("www.google.") =3D=3D 0 || _udn.indexOf(".google.") = =3D=3D 0 || _udn.indexOf("google.") =3D=3D 0) && _utcp=3D=3D'/' && = _udn.indexOf("google.org")=3D=3D-1) {=0A= return false;=0A= }=0A= return true;=0A= }=0A= function _uSP() {=0A= var s=3D100;=0A= if (_usample) s=3D_usample;=0A= if(s>=3D100 || s<=3D0) return true;=0A= return ((__utmVisitorCode(1)%10000)<(s*100));=0A= }=0A= function urchinPathCopy(p){=0A= var d=3Ddocument,nx,tx,sx,i,c,cs,t,h,o;=0A= cs=3Dnew Array("a","b","c","v","x","z");=0A= h=3D_uDomain(); if (_udn && _udn!=3D"") o=3D" domain=3D"+_udn+";";=0A= nx=3D_uNx()+";";=0A= tx=3Dnew Date(); tx.setTime(tx.getTime()+(_utimeout*1000));=0A= tx=3Dtx.toGMTString()+";";=0A= sx=3Dnew Date(); sx.setTime(sx.getTime()+(_ucto*1000));=0A= sx=3Dsx.toGMTString()+";";=0A= for (i=3D0;i<6;i++){=0A= t=3D" expires=3D";=0A= if (i=3D=3D1) t+=3Dtx; else if (i=3D=3D2) t=3D""; else if (i=3D=3D5) = t+=3Dsx; else t+=3Dnx;=0A= c=3D_uGC(d.cookie,"__utm"+cs[i]+"=3D"+h,";");=0A= if (c!=3D"-") d.cookie=3D"__utm"+cs[i]+"=3D"+c+"; path=3D"+p+";"+t+o;=0A= }=0A= }=0A= function _uCO() {=0A= if (!_utk || _utk=3D=3D"" || _utk.length<10) return;=0A= var d=3D'www.google.com';=0A= if (_utk.charAt(0)=3D=3D'!') d=3D'analytics.corp.google.com';=0A= _ubd.cookie=3D"GASO=3D"+_utk+"; path=3D"+_utcp+";"+_udo;=0A= var sc=3Ddocument.createElement('script');=0A= sc.type=3D'text/javascript';=0A= sc.id=3D"_gasojs";=0A= = sc.src=3D'https://'+d+'/analytics/reporting/overlay_js?gaso=3D'+_utk+'&'+= Math.random();=0A= document.getElementsByTagName('head')[0].appendChild(sc); =0A= }=0A= function _uGT() {=0A= var h=3Dlocation.hash, a;=0A= if (h && h!=3D"" && h.indexOf("#gaso=3D")=3D=3D0) {=0A= a=3D_uGC(h,"gaso=3D","&");=0A= } else {=0A= a=3D_uGC(_ubd.cookie,"GASO=3D",";");=0A= }=0A= return a;=0A= }=0A= var _utk=3D_uGT();=0A= if (_utk && _utk!=3D"" && _utk.length>10) {=0A= if (window.addEventListener) {=0A= window.addEventListener('load', _uCO, false); =0A= } else if (window.attachEvent) { =0A= window.attachEvent('onload', _uCO);=0A= }=0A= }=0A= =0A= function _uNx() {=0A= return (new Date((new Date()).getTime()+63072000000)).toGMTString();=0A= }=0A= ------=_NextPart_000_0241_01C85B7B.BC962280--