From: Subject: Plasticity of Bone Marrow-Derived Stem Cells -- Grove et al. 22 (4): 487 -- Stem Cells Date: Sun, 13 Jan 2008 18:12:54 +0100 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_002E_01C8560F.EAEC9310" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198 This is a multi-part message in MIME format. ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: text/html; charset="Windows-1252" Content-Transfer-Encoding: quoted-printable Content-Location: http://stemcells.alphamedpress.org/cgi/content/full/22/4/487?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&searchid=1&FIRSTINDEX=0&minscore=5000&resourcetype=HWCIT Plasticity of Bone Marrow-Derived Stem Cells -- Grove = et al. 22 (4): 487 -- Stem Cells
3D"Stem =20
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH SEARCH=20 RESULT
 3D"
3D" QUICK = SEARCH:   [advanced] 3D"
3D"
Author:
 Keyword(s):
Year:  Vol:  Page: 
3D"
3D"
This = Article
3D"
3D"Right Abs= tract=20 3D"Freely
3D"Right Full= =20 Text (PDF)
3D"Right Alert=20 me when this article is cited
3D"Right Alert=20 me if a correction is posted
3D"Right Citation Map
3D"
Services
3D"
3D"Right Similar=20 articles in this journal
3D"Right Similar=20 articles in PubMed
3D"Right Alert me=20 to new issues of the journal
3D"Right Download=20 to citation manager
3D"Right Reprints/= Permissions=20
3D"
Citing = Articles
3D"
3D"Right Citing=20 Articles via HighWire
3D"Right Citing Articles via Google = Scholar
3D"
Google = Scholar
3D"
3D"Right Articles by Grove, J. E. =
3D"Right Articles by Krause, D. S. =
3D"Right Search for Related Content =
3D"
PubMed
3D"
3D"Right PubMed=20 Citation
3D"Right Articles by Grove, J. E. =
3D"Right Articles by Krause, D. S.=20 =

Stem Cells=20 2004;22:487-500 http://www.stemcells.com/
=A9 = 2004 AlphaMed = Press=20

CONCISE REVIEW

Plasticity of Bone Marrow=96Derived Stem Cells=20

Joanna E. Grove, = Emanuela=20 Bruscia, Diane S. Krause =

Department of Laboratory Medicine, Yale University = School of=20 Medicine, New Haven, Connecticut, USA

Key Words. Adult stem cell =95 = Hematopoiesis =95=20 Plasticity

Correspondence: Joanna Grove, Ph.D., Yale University = School of=20 Medicine, P.O. Box 8035, 333 Cedar Street, New Haven, CT 06520-8035, = USA.=20 Telephone: 203-785-7089; Fax: 203-688-2748; e-mail: joanna.grove{at}yale.edu


3D"    ABSTRACT
Top
3D"Abstract
Stem Cells in Adult...
Evidence for Bone Marrow...
Current Challenges in Plasticity...
Lack of Reproducibility of...
Discussion
References
 
<= STRONG>Stem=20 cell plasticity refers to the ability of adult stem cells to = acquire=20 mature phenotypes that are different from their tissue of = origin.=20 Adult bone marrow cells (BMCs) include two populations of = bone marrow=20 stem cells (BMCs): hematopoietic stem cells (HSCs), which = give rise=20 to all mature lineages of blood, and mesenchymal stem cells = (MSCs),=20 which can differentiate into bone, cartilage, and fat. In = this=20 article, we review the literature that lends credibility to = the=20 theory that highly plastic BMCs have a role in maintenance = and repair=20 of nonhematopoietic tissue. We discuss the possible = mechanisms by=20 which this may occur. Also reviewed is the possibility that = adult=20 BMCs can change their gene expression profile after fusion = with a=20 mature cell, which has brought into question whether this = stem cell=20 plasticity is real.


3D"    STEM CELLS IN=20 ADULT BONE MARROW (BM)
Top
Abstract
3D"Stem Cells in = Adult...
Evidence for Bone Marrow...
Current Challenges in Plasticity...
Lack of Reproducibility of...
Discussion
References
 
T= he main=20 function of stem cells in adult tissue is to repair and = regenerate=20 the tissue in which they reside. Stem cells have the ability = to=20 self-renew and to differentiate into at least one mature cell = type.=20 Under normal conditions, stem cells divide to produce = progenitor=20 cells that can, depending on the tissue, go through a number = of=20 subsequent cell divisions and differentiation steps to = produce a=20 complex web of mature cells. Hematopoietic stem cells (HSCs) = are a=20 well-characterized population of self-renewing cells that = produce=20 progenitors that differentiate into every type of mature = blood cell=20 in a well-defined hierarchy [1].=20

Mesenchymal stem cells (MSCs), which reside in bone marrow as = well=20 as in other tissues (e.g., fat), adhere to plastic in vitro = and=20 expand in tissue culture with a finite lifespan of 15=9650 = cell=20 doublings. Under appropriate stimuli, MSCs differentiate in = vitro and=20 in vivo into adipocytes, chondrocytes, and osteoblasts [2,3].=20 Although MSCs are stem cells, capable of self-renewal and=20 multilineage differentiation, it is not yet clear to what = extent MSCs=20 are responsible for normal growth or maintenance in = vivo.

A relatively elusive adherent stem-cell population referred = to as=20 multipotent adult progenitor cells (MAPCs) can be isolated by = in=20 vitro growth of bone marrow cells (BMCs) in growth medium = containing=20 specific growth factors (e.g., epidermal growth factor and=20 platelet-derived growth factor) for several months while = maintaining=20 a relatively low cell density of 0.5=961.5 x 103 = cells/cm2.=20 MAPCs have the ability to form classical endodermal, = mesodermal, and=20 ectodermally derived cell types such as hepatocytes, = endothelial=20 cells, and neurons in vitro [4].=20 The pluripotentiality of MAPCs has been confirmed in vivo; = MAPCs can=20 contribute to multiple tissues (including brain, retina, = lung,=20 myocardium, skeletal, muscle, intestine, kidney, spleen, bone = marrow,=20 blood, and skin) in chimeric mice that are derived from = injection=20 of MAPCs into early blastocysts. Also, MAPCs can engraft=20 hematopoietic tissues (blood, bone marrow, and spleen), as = well as=20 mature epithelial cells of the lung, liver, and intestine = when=20 administered intravenously to sublethally irradiated adult = nonobese=20 diabetic/severe combined immunodeficient (NOD/SCID) mice [4].=20 Unlike hematopoietic cells, undifferentiated MAPCs do not = express=20 CD45, c-Kit, or Sca-1. These cells may represent a rare = subpopulation=20 of MSCs, or they may be a byproduct of the long-term in vitro = culture conditions used for their purification.


3D"    EVIDENCE FOR BONE=20 MARROW STEM CELL (BMC) PLASTICITY=20
Top
Abstract
Stem Cells in Adult...
3D"Evidence for Bone = Marrow...
Current Challenges in Plasticity...
Lack of Reproducibility of...
Discussion
References
 
<= STRONG>BMCs=20 to Skeletal Muscle
Muscle regeneration and repair are = thought to be=20 carried out by muscle-specific stem cells, called satellite = cells,=20 which are located between the myocytes and the basal lamina = of=20 skeletal muscle fibers [5=967].=20 Characteristic of stem cells, satellite cells are usually = quiescent=20 and have the ability to both self-renew and to generate new = skeletal=20 muscle fibers. Derivation of skeletal muscle myocytes from = BMCs has=20 been studied in vivo after muscle injury and in mouse models = of=20 degenerative muscle disease.

The first in vivo evidence of BM-derived cells contributing = to=20 muscle regeneration came from a study using BMCs from C57/MlacZ=20 transgenic mice that express the =DF-galactosidase (=DF-gal)=20 reporter gene under the muscle-specific myosin light chain = promoter=20 [8].=20 Unfractionated, adherent, or nonadherent BMCs were injected = directly=20 into the tibialis anterior muscle of immunodeficient mice 24 = hours=20 after damage was induced with cardiotoxin injection. As a = control,=20 each animal was injected with 105 purified satellite = cells=20 into a similarly damaged contralateral muscle. After 2=965 = weeks, four=20 of six mice injected with unfractionated BMCs had = =DF-gal+=20 nuclei within their skeletal muscle fibers. In their = contralateral=20 control leg, each animal had muscle fibers that had = incorporated the=20 satellite cells at a higher level of engraftment than that = observed=20 for BMCs [8].=20 The BMCs did not need to be injected directly into the = muscle; after=20 bone marrow transplantation (BMT), intravenously injected = cells=20 also differentiate into muscle cells in vivo. The location of = the =DF-gal+ nuclei within the muscle fibers of=20 transplant recipients suggested that both immature and mature = muscle=20 fibers developed from the BM donor cells [8].=20

Evidence that BMCs might be recruited to differentiate into=20 skeletal muscle fibers under physiologic conditions when the=20 local satellite cell population is depleted was obtained in=20 mouse models for Duchenne muscular dystrophy, mdx and=20 mdx4cv transgenic mice [9=9611<= /A>].=20 These mice lack functional dystrophin. Early in the disease, = the=20 muscle mass is maintained by resident satellite cells; = however, over=20 time, the muscle is replaced by connective tissue, thereby = leading to=20 fibrosis and muscular dystrophy [9].=20 Ten weeks after BMT, mdx mice transplanted with normal = BM had=20 donor-derived cells that costained for muscle-specific = markers=20 myogenin and myf-5, and some of these BM-derived muscle cells = expressed dystrophin [9].=20

Side-population (SP) BMCs, characterized by the ability to = extrude=20 Hoechst dye, and to fluoresce with a unique pattern on=20 fluorescence-activated cell sorter (FACS) analysis, can also = become=20 incorporated into skeletal muscle fibers. SP cells are=20 CD45+, CD34=96/low, = c-Kit+/dim,=20 Sca-1+ and enriched for HSCs [12<= /A>=9614<= /A>].=20 A potential problem with the mdx mouse model is that a = background of muscle fibers may spontaneously revert to = synthesize=20 normal dystrophin, so that the detection of dystrophin alone = is not=20 conclusive evidence that BMCs differentiate into functional = muscle=20 fibers. Twelve weeks post-BMT with SP cells, dystrophin is=20 expressed in up to 4% of myofibers, and of these=20 dystrophin-expressing fibers, donor-derived nuclei were = detected in=20 10%=9630% [10<= /A>].=20 BMCs were also transplanted into mdx4cv transgenic mice = that=20 exhibit an extremely low percentage (0.2%) of reverting = fibers.=20 Similar to previous experiments, BMCs demonstrated myogenic = potential=20 by engrafting into the skeletal muscles of mice with muscular = dystrophy. Normal dystrophin was expressed in these animals,=20 suggesting that the BMC-derived myoblasts were functional; = however,=20 the level of dystrophin-positive fibers averaged only 0.25%=20 throughout the 10-month period of analysis and never exceeded = 1% [15<= /A>].=20

In a rigorous study tracking the pathway of BMCs to satellite = cell=20 to myofiber, unfractionated green fluorescent protein-positive=20 (GFP+) BMCs were transplanted into irradiated = recipients [16<= /A>].=20 Irradiation served to both ablate the BM compartment and = decrease=20 satellite stem cell numbers in muscle tissue. GFP+,=20 BMC-derived satellite cells were identified in muscle tissue = of BMT=20 recipients by morphology and also by their ability to = self-renew and=20 differentiate into myotubes in vitro. The cells were = karyotyped, and=20 the "re-programmed" cells were diploid. The level of = BMC-derived=20 multinucleate muscle fibers in BMT-recipient mice was greatly = increased when the animals underwent physical activity for 6 = months=20 [16<= /A>].=20 This study is important because it provides evidence that BM = to=20 muscle differentiation occurs via repopulation of the muscle = stem=20 cell compartment. Although it is not yet known which BM=20 subpopulations have the ability to develop into muscle, the = data=20 obtained using SP cells suggest that a population enriched = for HSCs=20 is responsible [10<= /A>].=20 Muscle damage may not be a prerequisite for differentiation = from BM=20 to skeletal muscle. For example, 16 months post-BMT, = recipient mice=20 had engraftment of BMC into the panniculus carnosus muscle, = which is=20 much higher than what was seen in any other muscle analyzed,=20 suggesting that BMCs may contribute to regeneration of the = panniculus=20 carnosus under normal physiologic conditions [17<= /A>,18<= /A>].=20

Although the studies described above provide evidence that=20 differentiation from BM to muscle occurs via repopulation of = the=20 muscle stem cell compartment, some of the incorporation of=20 marrow-derived cells into skeletal muscle may be due to = fusion. Work=20 by Ye et al. [19<= /A>],=20 using a Cre-Lox system as a readout for cell=96cell fusion, = supports=20 this theory. They used, as recipients of BMT, mice that have = a=20 Stop-Lox-=DF-gal cassette, which allows for expression of = =DF-gal by a=20 cell only if the nonmammalian Cre recombinase enzyme is = expressed. As=20 the BM donors, they used transgenic mice that express Cre = from the=20 lysozyme M promoter, which is active predominantly, although = not=20 exclusively [19<= /A>],=20 in myeloid cells. After BMT, recipients had = =DF-gal=96expressing=20 muscle fibers. Although these data strongly suggest that the=20 =DF-gal+ muscle may have developed by fusion of a=20 donor-derived myeloid cell with a pre-existing muscle fiber, = they are=20 not conclusive because complete cell-type specificity of the=20 Lys-M promoter is lacking [19<= /A>].=20

BMCs to Cardiac Muscle
BMCs can also incorporate = into=20 cardiac muscle fibers. Data showing differentiation of = cardiac=20 myocytes in vitro and in vivo suggest that cell therapy may = be=20 effective for cardiac disorders such as acute myocardial = infarction=20 [20<= /A>],=20 chronic ischemia [21<= /A>,22<= /A>],=20 and cardiac graft rejection [23<= /A>].=20 In vivo, BM-derived stromal cells and mesenchymal stem cells = can=20 differentiate into cardiac myocytes, as assessed by = morphology,=20 spontaneous beating, or muscle-specific protein expression = [24<= /A>,25<= /A>].=20 One of the manipulations that induces this differentiation is = addition of 5-azacytidine to the growth medium. This drug = leads to=20 DNA demethylation and may thereby activate previously = silenced=20 regions of the genomic DNA.

Myocardial infarction in humans and in animal models by ligation = of the left main coronary artery leads to death of myocytes = and=20 vascular structures in the affected area. Left untreated, the = remaining myocytes do not reconstitute the injured tissue, = and=20 scarring occurs, which can lead to deterioration of cardiac = function=20 [26<= /A>=9628<= /A>].=20 Injection of lineage-depleted, c-Kit+ BMC-derived=20 hematopoietic progenitor cells directly into intact = myocardium=20 bordering the infarct area can promote regeneration of = functional=20 myocardium [20<= /A>].=20 BMCs migrate into the necrotic area of the infarcted = myocardium and=20 regenerate myocytes, as well as vascular structures. Even = though the=20 thinning of the infarcted heart is only partially restored,=20 BM-derived myocytes appear to be able to restore electrical=20 connections, leading to a functional improvement of = ventricular=20 activity.

HSCs can be mobilized from BM to the peripheral blood by = administration=20 of hematopoietic growth factors. When stem cell factor (SCF)=20 and granulocyte colony-stimulating factor (G-CSF) were used = to=20 mobilize HSCs 5 days before and 3 days after ligation of the = left=20 coronary artery in mice, there was significantly less = mortality,=20 improved cardiac function, and more tissue repair with = proliferating=20 myocytes and newly formed vessels than in the control animals = that=20 had not received growth factors [20<= /A>].=20 Based on these data, it is tempting to speculate that = mobilized=20 BMCs may respond to coronary occlusion by migrating to the = site=20 of injury and generating new myocardium. However, this study=20 was not designed to assess whether the circulating BM-derived = cells directly contributed to the improved cardiac outcome.=20 Consistent with these findings, among patients who have had=20 acute myocardial infarction, those in whom immature = hematopoietic=20 cells are mobilized from the bone marrow show a statistically = significant improvement in ejection fraction 6 months after=20 myocardial infarction than similar patients in whom no = mobilization=20 of hematopoietic progenitors occurred [29<= /A>].=20

Engrafted BM SP cells can also contribute to myocardial tissue.=20 When BMT recipients of =DF-gal+ BM SP cells = underwent=20 occlusion and reperfusion of the left descending coronary = artery,=20 BMC had contributed to regenerating heart tissue as both = endothelial=20 cells and myocytes. These =DF-gal+ cells costained = for=20 3D{alpha}-actinin and seemed to be connected to host myocytes [13<= /A>].=20

Stromal cells injected into scarred ventricles 3 weeks after=20 myocardial infarction can also engraft in the wounded tissue=20 and express troponin 1 and myosin heavy chain and can = increase=20 cardiac function significantly [24<= /A>].=20 In a similar in vivo experiment, rat bone marrow stromal = cell-derived=20 cardiac myocytes expressed contractile proteins and connexin = 43 [30<= /A>].=20 This gap junction protein was seen between BMC-derived = myocytes and=20 host myocytes, suggesting the donor-derived cells integrated=20 themselves into the cardiac muscle network that was necessary = for=20 electrophysiological function [30<= /A>].=20

BMC-derived cardiac myocytes also may have therapeutic potential = for the treatment of chronic cardiac graft rejection after = heart=20 transplantation. Immunologic graft rejection compromises = cardiac=20 function due to fibrosis and scarring [31<= /A>,32<= /A>].=20 MSCs home to and engraft within allogeneic cardiac grafts = that are=20 undergoing graft rejection. IV injection into rats of=20 =DF-gal+ rat MSCs 1 week before and 1, 2, and 3 = weeks after=20 allogeneic heart transplantation resulted in localization of = the MSCs=20 to fibrotic regions of the graft and significantly reduce = graft=20 survival time. Although most of the MSC-derived cells were=20 fibroblastic in appearance, a small proportion of the = MSC-derived=20 cells expressed desmin, which is unique to cardiac myocytes = in the=20 heart [33<= /A>].=20

To assess the ability of human BMCs to incorporate into cardiac=20 tissue, CD34-selected cells from mobilized human peripheral=20 blood were injected into rats 48 hours after ligation of the=20 left anterior descending coronary artery [34<= /A>].=20 Two weeks post-transplantation, animals that had received = human cells=20 had an increase in vascularity and cellularity within the = area of=20 infarct, as well as decreased fibrosis, over that of the=20 sham-operated controls. Moreover, using echocardiography, = cardiac=20 output, and ventricular volume measurements, cardiac function = had=20 improved in rats that received these CD34+ cells = following=20 ischemic injury [34<= /A>].=20

BM-derived cells may also differentiate into cardiac myocytes = in=20 humans. In a retrospective study of heart transplant recipients, = the=20 heart tissue of eight males who had received female hearts = showed=20 high levels of chimerism; up to 18% of myocytes, 20% of = coronary=20 arterioles, and 14% of capillaries within the allogeneic = hearts were=20 Y-chromosome positive [35<= /A>].=20 The kinetics of this engraftment are not yet known, nor is it = known=20 whether BM engraftment into cardiac tissue is a result of = fusion with=20 endogenous cells. The relatively high level of engraftment is = likely=20 related to cardiac injury secondary to rejection because the = hearts=20 of female patients who had undergone BMT from male donors had = an=20 average of only 0.23% Y positive, =DF-sarcomeric = actin-positive=20 cardiac myocytes [36<= /A>].=20 The normal karyotype of these cells suggested that fusion had = not=20 occurred. The relatively low percentage of BMC-derived = myocytes may=20 reflect the degree to which BMCs contribute to heart tissue = under=20 physiological conditions [36<= /A>].=20

Clinical studies investigating the effect of injecting = autologous=20 BMCs into humans with chronic myocardial ischemia show that=20 intramyocardial injection of BM-derived cells is safe and may = improve outcome in treated patients. For example, Perin et = al.=20 [22<= /A>]=20 evaluated 14 patients with chronic cardiac ischemia who had = been=20 treated with direct intracardiac injections of approximately = 25=20 million mononuclear BMCs per patient. Cells were injected = into=20 ischemic areas containing viable myocardium, which the = researchers=20 believed was necessary to support neovascularization. After 4 = months,=20 the patients had improved cardiac perfusion and contractility = compared with their baseline measurements. It is not known = whether=20 the injected cells facilitated repair in myocardial tissue = directly=20 (by engrafting as cardiac myocytes or endothelial cells) or=20 indirectly (by stimulating angiogenesis or myogenesis). In a = related=20 clinical trial, autologous skeletal muscle cell = transplantation into=20 patients with heart disease undergoing left ventricular = assist device=20 implantation proved to be safe [37<= /A>].=20

As of January 2004, data from several clinical trials in which=20 marrow-derived cells have been injected into myocardial = tissue=20 in humans have been reported [21<= /A>,=20 22<= /A>,=20 38<= /A>=9642<= /A>].=20 No short-term toxicity or adverse events have been reported. = Although=20 limitations of each of the studies have hindered our ability = to=20 conclude whether a therapeutic benefit of administering=20 marrow-derived cells has occurred, the data are promising [43<= /A>].=20

BMCs to Liver
Liver has at least two internal = mechanisms=20 for repair and maintenance. The primary mechanism of liver = generation=20 and repair is proliferation and hypertrophy of existing = hepatocytes=20 and cholangiocytes. When liver is severely damaged and = endogenous=20 hepatocytes cannot divide, then liver repair is facilitated = by oval=20 cells, which act as tissue-specific stem cells. It is = generally=20 agreed that oval cells, located around bile ducts with = oval-shaped=20 nuclei, comprise a resident bipotent liver stem cell = population [44<= /A>].=20 Oval cells proliferate and differentiate in rats after = hepatic=20 injury with carbon tetrachloride (CCl4) when endogenous = hepatocyte proliferation is suppressed by = 2-acetylaminofluorene=20 (2-AAF) [23<= /A>].=20 When BMT using unfractionated bone marrow from dipeptidyl = peptidase=20 IV-positive (DDPIV+) rats into DDPIV-null = (DDPIV=96)=20 rats was performed, followed by liver damage with 2-AAF and=20 CCl4 2 weeks later, DDPIV+ donor-derived = oval cells=20 and hepatocytes developed [23<= /A>].=20 BMC-derived hepatocytes ranged from 0.76%=962.2% of total = hepatocytes.=20 In humans, sex-mismatched BMT recipients have BM-derived = hepatocytes=20 and cholangiocytes, suggesting that donor-derived marrow = cells may=20 have engrafted as oval cells [45<= /A>,46<= /A>].=20

Results from xenotransplantation of human BMCs into sublethally=20 irradiated immunodeficient mice suggest that HSC-enriched = populations=20 contain cells that engraft as mature hepatocytes in the = liver.=20 Lin=96CD38=96CD34=B1ClqRp+ cells=20 contribute to hematopoiesis in sublethally irradiated = NOD/SCID mice=20 and engraft as mature human hepatocytes [47<= /A>].=20 In a related xenotransplantation study, human hepatocytes = developed=20 in the livers of mice that had been injected with either = human=20 CD34+ BMCs or CD34+ cord blood cells = and=20 treated with the hepatotoxin CCl4 1 month = post-transplantation=20 [48<= /A>].=20 The level of human albumin RNA expressed in transplanted, = injured=20 mice increased significantly with human hepatocyte growth = factor=20 treatment [48<= /A>].=20

To determine whether a single marrow-derived cell can = differentiate=20 into both hematopoietic and epithelial cell types, Krause et=20 al. [49<= /A>]=20 performed transplanted single male-derived BMCs into lethally = irradiated female mice. The HSC population used was isolated = by a=20 multistep process. First, the male mouse BMCs were purified = by=20 elutriation, and the lineage was depleted to enrich for = long-term=20 repopulating cells. These cells were then labeled with PKH26, = a=20 membrane dye, and then transplanted into primary lethally = irradiated=20 female hosts. After 48 hours, the PKH26-labeled cells were = recovered=20 from the bone marrow, and single cells were transplanted into = lethally irradiated secondary female recipients using = limiting=20 dilution. In the mice that survived the single-cell = transplantation,=20 there was male-derived hematopoietic reconstitution, and all = of the=20 mice had Y chromosome=96positive epithelial cells in the = lung, liver,=20 skin, and gastrointestinal (GI) tract [49<= /A>].=20 Another murine transplantation study demonstrated that a = single,=20 long-term, bone marrow=96repopulating c-Kit+, = Thy1.110,=20 Lin=96, Sca-1+ (KTLS) cell could, in a rare = event,=20 incorporate into the liver as hepatocytes and into the = central=20 nervous system as Purkinje cells [50<= /A>].=20

Functionality of BM-derived hepatocytes was demonstrated in = a=20 mouse model for the metabolic liver disease tyrosinemia type = I [51<= /A>].=20 These mice are deficient in the enzyme fumarylacetoacetate = hydrolase=20 (FAH) and must be maintained on a drug,=20 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione = (NTBC) to=20 survive. FAH-deficient mice that had undergone BMT using = wild-type=20 (FAH+) donors were taken off NTBC 3 weeks = post-transplantation,=20 and four of nine mice survived with substantially improved = liver=20 function. Livers of these mice had large segments containing=20 functional FAH+ hepatocytes that were derived from the = BM=20 donor. The dramatic survival advantage of the marrow-derived=20 hepatocytes in this liver disease model allowed BM-derived=20 hepatocytes to expand and reconstitute up to 50% of the = recipient=20 liver. In this model system, data suggest that the mechanism = by=20 which the BM-derived cells changed their gene expression = pattern=20 to that of mature functional hepatocytes is likely to be = fusion=20 with damaged recipient liver cells [52<= /A>,53<= /A>].=20

Kanazawa and Verma [54<= /A>]=20 tested the ability of BMCs to generate hepatocytes in other = mouse=20 models of liver disease: an albumin-urokinase transgenic = mouse and a=20 hepatitis B transgenic mouse. When these animals underwent = lethal=20 irradiation and transplantation with bone marrow from GFP or = =DF-gal=20 transgenic mice, no GFP+ or =DF-gal+ = hepatocytes=20 were found. However, when the BMT recipient mice were treated = with=20 the hepatotoxin CCl4, then donor-derived = hepatocytes (as=20 assessed by Y chromosome fluorescence in situ hybridization = [FISH]=20 methodology) were identified in their liver tissue showing = that=20 BMC-to-liver-cell plasticity did occur at a frequency of=20 approximately 1 in 8 x=20 104 hepatocytes [54<= /A>].=20 This paper highlights a problem that has been picked up by = others:=20 Transgene expression is a less consistent means of detecting=20 donor-derived cells than is Y chromosome in situ = hybridization, and=20 neither of the disease models was analyzed with Y chromosome = in situ=20 hybridization. We need to take this into account when = analyzing=20 published results based on GFP or =DF-gal expression. =

MAPCs, derived from mouse, rat, and human bone marrow can = differentiate=20 into functional hepatocyte cells in vitro [55<= /A>].=20 Optimal conditions for in vitro differentiation of MAPC to = liver were=20 achieved by plating the cells at a density of 2 x 104 cells per cm2 = on=20 a combination of extracellular matrix proteins (matrigel) in=20 the presence of fibroblast growth factor-4 (FGF-4) and human=20 growth factor (HGF). After 2 weeks the cells were = characterized=20 as hepatocyte-like cells, expressing early and late markers = of=20 hepatocytes. The cells also had functional characteristics of = hepatocytes, including the production and secretion of urea = and=20 albumin, cytochrome P450 activity, and uptake of low-density=20 lipoprotein.

BMCs to Skin
Adult skin contains multipotent = tissue stem=20 cells that can self-renew and give rise to epidermis, = sebaceous=20 glands, and hair follicles [56<= /A>].=20 This putative stem cell resides in the bulge region of hair = follicles=20 [57<= /A>].=20 Long-term repopulating BMCs can differentiate into=20 cytokeratin-positive epithelium of the epidermis [49<= /A>].=20 Using a BMT model, BMC-derived cells were found in the bulge=20 region of the follicle, yet they did not show clonal = expansion.=20 In humans, female recipients of male BMTs had BMC engraftment = into the epidermis (as well as the GI tract and liver), as = determined=20 by colocalization of the donor Y chromosome and cytokeratin = in=20 recipient tissue [58<= /A>].=20 In a separate study, skin biopsies from females who had = undergone=20 transplantation with male peripheral blood stem cells were = assessed=20 not only for the presence of Y-positive epithelial cells but = also for=20 skin stem cells as assessed by self-renewal in vitro. = Consistent with=20 other reports, epidermal tissue from the patients had=20 cytokeratin-positive, Y-positive cells, suggesting that they = were=20 BM-derived keratinocytes. The degree of engraftment of = marrow-derived=20 keratinocytes did not correlate with the degree of = graft-versus-host=20 disease (GVHD) in the skin ([59<= /A>],=20 J. Grove, unpublished data). No donor-derived keratinocytes = grew in=20 vitro, suggesting that the donor-derived cells detected in = vivo could=20 not survive under the in vitro culture conditions used [59<= /A>].=20

BMCs to GI Tract
The GI tract of mammals is = thought to=20 have a resident population of tissue stem cells that = contribute to=20 the continual turnover of the gut epithelium. The putative=20 multipotent intestinal stem cells reside in the crypts and = give rise=20 to all types of epithelial cells, columnar absorptive = enterocytes,=20 Paneth cells, goblet cells, and enteroendocrine cells [60<= /A>=9662<= /A>].=20 BM-derived intestinal epithelial cells were first shown by = Krause et=20 al. [49<= /A>],=20 in the single-cell study described above. Since then, data=20 provided by other studies have corroborated this finding. In = one=20 study, four female cancer patients receiving sex-mismatched = BMT=20 were chosen for analysis because they displayed symptoms of=20 chronic GVHD, acute GVHD, peptic ulcer, or inflammation of = the GI=20 tract. Donor-derived epithelial cells were identified in the = GI=20 tract of each of the BMT recipients [63<= /A>].=20 The male donor cells were found in all sections of the GI = tract,=20 including the esophagus, stomach, small intestine, and colon, = and=20 they appeared to increase during episodes of GVHD. This is in = contrast to findings in the human skin in which the = percentage of=20 BM-derived keratinocytes was not affected by the GVHD status = of the=20 patient [58<= /A>,59<= /A>].=20 Chromosomal karyotyping ruled out the possibility that = Y-positive,=20 cytokeratin-positive cells were a result of stable fusion [63<= /A>].=20 Donor-derived, cytokeratin-positive cells were found in the = GI=20 tract of two female cancer patients who received = CD34+-selected=20 peripheral blood transplants from brothers following a = myeloablative=20 treatment [58<= /A>].=20 While these patients also had episodes of GVHD, no = correlation was=20 found in these two patients between GVHD and BMC engraftment. = Taken=20 together, these studies support the theory that a BMC = population=20 enriched for HSC contains cells that can differentiate into=20 intestinal epithelial cells.

BMCs also differentiate into intestinal myofibroblasts in mice = and=20 humans [64<= /A>].=20 The GI tract of female mice that had been transplanted with = male BMCs=20 were analyzed 7, 14, and 42 days post-transplantation by FISH = for the=20 Y chromosome and immunohistochemistry for smooth muscle actin = (SMA),=20 desmin, F4/80 (macrophages), and CD34 (hematopoietic = progenitors).=20 Around the crypt region, donor-derived myofibroblasts=20 (SMA+, desmin=96, F4/80=96, = CD34=96=20 cells) were seen in BMT recipients after 7 days; by 14 days, = 49.4% of=20 myofibroblasts around the crypt were marrow-derived, and = after 6=20 weeks, 57.6% were Y-chromosome positive [64<= /A>].=20 Similarly in women who had undergone BMT, Y-positive, = SMA-positive=20 pericryptal myofibroblasts were found in three of three = patients=20 studied [64<= /A>].=20 The fact that BMCs differentiate into myofibroblast cells = following=20 BMT suggests that BM-derived cells may have a supportive role = in=20 the regeneration of intestinal epithelium by providing = soluble=20 factors, cytokines, and the necessary milieu to produce new=20 tissue.

BMCs to Lung
Type II pneumocytes are the putative = lung=20 stem cells responsible for alveolar tissue turnover. In = response to=20 injury, these cells proliferate to create more type II cells = and also=20 differentiate into type I pneumocytes [65<= /A>].=20 BMCs capable of long-term hematopoietic reconstitution can = become=20 type II pneumocytes following BMT [49<= /A>].=20 BM-derived type II pneumocytes have been identified by = colocalization=20 of the Y chromosome and cytokeratin, as well as by expression = of=20 surfactant protein B mRNA, which is specific to type II = pneumocytes=20 in the alveoli [49<= /A>].=20 After BMT, the level of engraftment of donor-derived = epithelial cells=20 is greater in the lung than in other epithelial tissues, = perhaps=20 because of radiation-induced pneumonitis [66<= /A>].=20 Following lethal irradiation and BMT with male BM, BM-derived = cells=20 begin to repopulate the damaged alveolar tissue after 5=967 = days, and=20 clusters of BM-derived epithelial cells are present by 2 = months and=20 thereafter. The percentage of donor-derived cells that = differentiate=20 into type II pneumocytes ranges from 0.7% at day 5 to 14% at = 6=20 months [66<= /A>].=20 BM-derived type II pneumocytes also developed in mice = transplanted=20 with CD34+Lin=96 male BM and analyzed 8 = months=20 post-transplantation, confirming that a BM subpopulation = enriched=20 for hematopoietic progenitors can engraft in irradiated lung=20 tissue as pneumocytes.

Marrow stromal cells may also be able to incorporate into = epithelial=20 tissue in the lung. Kotton et al. [67<= /A>]=20 used a bleomycin injury protocol to damage the alveolar = tissue of=20 mice before injecting plastic-adherent BMCs that had been = cultured in=20 vitro for 10 days. The injected cells formed clusters of type = I=20 pneumocytes in vivo after 30 days, and analysis at shorter = time=20 points suggested that BMCs differentiate directly into type I = pneumocytes rather than first engrafting as type II cells. = Because=20 the marrow-derived cell population was not depleted of=20 CD45+ hematopoietic cells, it cannot be determined = whether=20 MSCs were responsible for the observed engraftment of = pneumocytes.=20 More recently, a group performed a similar study using = purified MSCs.=20 The MSCs were isolated from bleomycin-resistant male mice by = plastic=20 adherence, and then hematopoietic progenitors were removed by = immunodepletion. These cells were injected intravenously into = bleomycin-sensitive female mice that had been exposed to = bleomycin.=20 Type II pneumocytes were isolated and analyzed by real-time=20 polymerase chain reaction (PCR) and FISH for Y chromosome. = Both=20 methods of analysis suggested the presence of male, = BM-derived type=20 II pneumocytes [68<= /A>].=20

In a small study of gender-mismatched human lung = transplantation,=20 6%=9626% of bronchial epithelial cells, 9%=9620% of = pneumocytes,=20 and 9%=9624% of seromucous glands were recipient-derived [69<= /A>].=20 The investigators developed a microdissection and PCR = technique to=20 detect donor-derived cells, which resulted in data comparable = to=20 those obtained using Y-chromosome in situ hybridization. A=20 correlation between the level of recipient engraftment and = the degree=20 of chronic injury was noted, which supports other studies = finding=20 increasing numbers of BM-derived cells in the lungs of = animals who=20 had undergone bleomycin injury [67<= /A>,68<= /A>].=20 It cannot be determined whether the recipient-derived lung = cells=20 in the transplanted lungs were from bone marrow. Again, = consistent=20 with tissue damage facilitating the transition from BM to = epithelial=20 cell, no donor-derived lung cells were detected in BMT = recipients=20 [69<= /A>].=20 This is a problem because the authors regarded this experimental=20 group as a good negative control for the microdissection and=20 PCR technique. These data differ from those of Suratt et al.=20 [10= 8],=20 who showed that two of three female recipients of BMT using = male=20 donor cells had a 2.5%=968% epithelial donor chimerism in = biopsied lung=20 tissue as detected by Y-chromosome FISH. It is likely that = tissue=20 injury, while not sufficient, is necessary for engraftment of = marrow-derived cells as epithelial cells. This is a critical=20 discovery, as it may limit the therapeutic potential of using = marrow-derived cells to treat diseases in which tissue injury = does=20 not occur. For example, in the absence of tissue injury, no=20 engraftment of nasal epithelial cells is detectable in female = cystic=20 fibrosis patients who, for treatment of malignancy, had = undergone BMT=20 with male donors [70<= /A>].=20 To date, there is no evidence that BMCs can perform the = normal=20 functions of lung epithelial cells.

BMCs to Pancreas
BMCs can also differentiate into = pancreatic endocrine =DF cells [71<= /A>,72<= /A>].=20 For these studies, bone marrow donors were double-transgenic = mice=20 that express Cre recombinase on an insulin promoter (INS2-CRE) = and=20 contain three translational stop codons flanked by Lox P = sites=20 upstream of enhanced green fluorescent protein (GFP) on the = ROSA26=20 locus promoter (ROSA-stoplox-GFP) [71<= /A>].=20 When the insulin promoter is active in cells from these mice, = Cre=20 recombinase excises the stop codons so that GFP is expressed. = BMCs=20 from male transgenic mice were transplanted into lethally=20 irradiated wild-type recipients, and the mice that survived = had Y=20 chromosome=96positive peripheral blood cells. Moreover, = GFP-positive=20 cells were found in the islets; these cells expressed insulin = and=20 transcription factors specific for =DF cells. To test whether = BMCs=20 were incorporated as pancreatic =DF cells by fusion, a=20 sex-mismatched Cre-Lox approach was used. BMT was performed = using BM=20 from single-transgenic male mice that express Cre recombinase = on the=20 insulin II promoter. The recipients were lethally irradiated = female=20 ROSA-stoplox-GFP recipients. In this situation, GFP will be = expressed=20 only if a donor-derived cell that has an active insulin = promoter is=20 fused to a recipient cell. Although male pancreatic =DF cells = were=20 found in the islets of recipient mice, no GFP expression was = observed=20 [71<= /A>].=20 The investigators concluded that BMCs can differentiate = toward a=20 pancreatic endocrine =DF-cell phenotype in vivo without cell=20 fusion.

BM-derived pancreatic islet cells were shown to be functional = in a=20 mouse model of chemically induced diabetes. Streptozotocin=20 (STZ)-treated mice have destruction of their pancreatic =DF = cells=20 with subsequent lack of insulin and resultant hyperglycemia. = When=20 STZ-treated mice were transplanted with c-Kit+ BMCs, a=20 marked reduction of serum glucose occurred within 4=967 = days=20 post-transplant [72<= /A>].=20 Although the investigators saw donor-derived = insulin-producing cells=20 in the pancreas, it was thought that the decrease in = hyperglycemia=20 was not due directly to development of BM-derived =DF cells=20 incorporating into the pancreas, but rather to stimulation of = endogenous cells to proliferate and produce insulin. The = reasons were=20 (a) the amelioration of hypoglycemia resulted in 4=967 days=20 post-transplant, at which time no insulin-positive, = GFP+=20 cells were detectable yet in the islets; (b) BrdU costaining = showed=20 that the majority of proliferating cells in the pancreas = post-BMT=20 were GFP=96cells; and (c) there were not many=20 insulin-producing GFP+ cells over time [72<= /A>].=20 However, it may be that transgene (GFP) expression was turned = off,=20 and it would have been helpful to check for BM-derived cells = using=20 more reliable markers such as the Y chromosome.

BMCs to Kidney
Sex-mismatched transplantation = models have=20 been used to assess BM-derived renal tubular epithelial = cells.=20 Lethally irradiated female mice receiving BMT from male = donors have=20 kidney cells that costain for the Y chromosome and for the = epithelial=20 cell=96binding lectins Ricinus communis, Lens = culinaris,=20 and Pisum sativum [73<= /A>].=20 These cells also express the cytochrome P450 enzyme CYP1A2,=20 suggesting functionality. In kidney biopsies from male = patients=20 who had been transplanted with kidneys from female donors, = 1.8%=9620%=20 of renal tubule epithelial cells were BMC-derived [73<= /A>].=20 This finding was corroborated by studies in which BM from a=20 transgenic lacZ-positive mouse was transplanted into=20 sub-lethally irradiated mice and ischemic renal injury was = induced 16=20 weeks post-transplantation [74<= /A>].=20 BM-derived tubules were identified by costaining for =DF-gal = and=20 megalin, a specific renal proximal tubule marker. The incorporation = of BMC into renal tissue only occurred when Lin=96,=20 c-Kit+, and Sca-1+ hematopoietic = progenitors=20 were used as donor cells and not when more mature = (Lin+)=20 cells were injected into recipient mice [74<= /A>].=20

BMCs to Central Nervous System (CNS)
The main = classes of=20 cells in the CNS are nerve cells (neurons) and glial cells. = Glial=20 cells are divided into two major classes: macroglia = (astrocytes,=20 oligodentrocytes) and microglia. Neural and macroglial cells = derive=20 from the ectodermal embryonic layer. Microglia, which = represent=20 approximately 5%=9620% of glial cells, are believed to be = derived from=20 bone marrow [75<= /A>,76<= /A>].=20 Historically, the mammalian CNS was considered to belong to = a=20 class of nonrenewable tissues [77<= /A>],=20 but this long-standing principle of neuroscience is being = challenged=20 by studies carried out in the last decade, which have shown = neuronal=20 progenitor cells that are capable of cell division in the = CNS.=20 Although the function and longevity of these cells are still = being=20 investigated, unambiguous evidence for adult neurogenesis in = mammals=20 has been demonstrated in the dentate gyrus and olfactory bulb = [77<= /A>,78<= /A>].=20 Recently, dividing neuronal cell populations have been found = in=20 the spinal cord as well [77<= /A>].=20 Several papers (reviewed below) suggest that BMC can = differentiate=20 into CNS cells, including neurons, oligodendrocytes, and = astrocytes,=20 both in vivo and in vitro.

In vitro studies on BMCs to CNS plasticity focus on the capacity = of the stromal BMC population to self-renew and to = differentiate=20 into neuronal phenotypes. Rat stromal cells can adopt a = neuronal-like=20 phenotype after being cultured in medium containing butylated = hydroxy anisole (BHA), dimethylsulfoxide (DMSO), and=20 =DF-mercaptoethanol. The cells display long cell processes = and express=20 the markers neuronal-specific esterase and neurofilament = medium=20 (NFM). Human MSCs differentiate into cells that = morphologically=20 resembled progenitors of neuronal cells and expressed neural = markers=20 when grown in medium containing 3-isobutyl-1-methylxanthine=20 (IBMX) and cAMP [79<= /A>,80<= /A>].=20 Using culture medium containing growth factors (epidermal = growth=20 factor [EGF] or brain-derived neurotrophic factor [BDNF]) and = retinoic acid, or coculturing with fetal mouse mesencephalic = cells,=20 Sca1=96 BM cells express neuron (NeuN) and = astrocytic (glial=20 fibrillary acidic protein [GFAP]) markers [80<= /A>].=20 Similar results are obtained with CD34=96 BMCs = cultured in=20 vitro in the presence of fibroblast, epidermal, and nerve = growth=20 factors (FGF, EGF, NGF) and retinoic acid [81<= /A>].=20

Under cytokine stimulation, MAPCs change morphologically, = resembling=20 astrocytes, oligodendrocytes, and neurons. In addition, when=20 introduced into early blastocysts, MAPCs contribute to the = formation=20 of neurons and astrocytes throughout the brain, including the = cortex, striatum, hippocampus, thalamus, and cerebellum. = However,=20 when these cells are infused intravenously into sublethally=20 irradiated adult mice, no significant engraftment of mouse = MAPC=20 occurs in the brain [82<= /A>].=20

Human fetal hematopoietic stem/progenitor=20 CD34+/CD133+/CD3=96 BMCs = generate=20 neuronal progenitor-like cells that express nestin and BMP-2 = when=20 they are cultured in astrocyte-conditioned medium or are = cocultured=20 with astrocytes. This BMC subpopulation, enriched for = neuronal=20 progenitor cells, could also differentiate into astrocytes=20 (GFP+; S100+) under defined culture conditions [83<= /A>].=20 Reviewing the in vitro studies, it must be pointed out that=20 different laboratories use different culture conditions and=20 start from different subpopulations of BMCs. This is not = necessarily=20 a negative aspect of these studies; rather, the data confirm=20 that there are several pathways to trigger BMCs to = differentiate=20 in vitro into neuronal-type cells. The ability of BM-derived=20 cells to differentiate into cells of the CNS has been = assessed=20 in vivo as well. BM-derived cells expressing the astrocyte = marker=20 GFAP develop in both the white and gray matter of the brain = of=20 myeloablated murine BMT recipients [76<= /A>].=20 Donor-derived GFAP+ cells also form in the CNS = after=20 direct administration of MSCs into the lateral ventricles of=20 3-day-old mice. In these same recipients, donor-derived cells = expressing neuron-specific neurofilament protein were present = in the=20 reticular formation of the brain stem [84<= /A>].=20 Similarly, in a patient who had received a BMT as an infant,=20 donor-derived neuron-like cells (7 in 10,000) were found in = the brain=20 after 1 year [85<= /A>].=20 These cells occurred in clusters, suggesting that a single = progenitor=20 cell may have expanded before differentiation.

Injection of the cytokines G-CSF and SCF after BMT may stimulate = acquisition of BM-derived cells in the CNS of 1-day-old pups = or=20 adult mice [86<= /A>,87<= /A>].=20 Cytokine-treated transplanted animals have a threefold = increase in=20 BM-derived neuron-like cells in the temporal cortical area = and=20 approximately a twofold increase in the olfactory bulb = compared with=20 untreated transplanted mice. Cytokine-treated mice that = received=20 transplantation at birth displayed a higher number of BM=20 donor=96derived neurons than mice that were transplanted in = adulthood=20 [88<= /A>].=20

To test which BMCs can differentiate into neuronal cells,=20 c-Kit+ BMCs were transplanted intracerebrally into = neonatal mouse brains. After 1 week, BM-derived cells = expressing the=20 oligodendrocyte marker (O4) were present in the ependymal = layer, and=20 those with neuronal character (=DF-III tubulin) were in the=20 subventricular zone, striatum, and cerebral cortex [89<= /A>].=20 In contrast, c-kit=96 BMCs did not differentiate = into cells=20 with a neuronal phenotype.

Studies marking BMCs with retroviruses have also identified=20 BMC-derived cells in the CNS. Whole BMCs cultured for 48 = hours=20 in interleukin-3 (IL-3), interleukin-6 (IL-6), and SCF, and=20 subsequently transduced with a retroviral vector encoding = GFP,=20 were injected into lethally irradiated mice. Within 1 month,=20 rare GFP+ NeuN-expressing cells were detected in the=20 olfactory bulb; at 12=9615 months post-transplant, up to 0.1% = fully developed cerebellar Purkinje neurons expressed GFP and = the Purkinje cell antigen calbindin-D28K [90<= /A>].=20 These cells displayed the typical morphology of Purkinje = cells with=20 extensive dendritic arborization and actively expressed -aminobutyric acid (GABA)=96synthesizing enzyme, = thereby=20 strongly suggesting neurotransmitter activity [90<= /A>].=20

A single Purkinje cell was also noted in a different experiment = in=20 which GFP+ BMC hematopoietic progenitor (KTLS) cells = from=20 a transgenic donor were transplanted into a lethally = irradiated=20 host. In this experiment, only one Purkinje cell was found in = four mice analyzed [50<= /A>].=20 Subsequent studies show that the nuclei of the BMCs were = reprogrammed=20 to express Purkinje-specific genes after cell fusion of a = BM-derived=20 cell with a mature Purkinje cell [91<= /A>,92<= /A>].=20 Despite this unexpected mechanism of formation, these data = suggest=20 that BMCs can be used as vehicles for gene therapy to the = brain.=20

BMC incorporation into neuronal tissues is enhanced after tissue = injury. When MSCs are injected into the striatum and cortex = of=20 previously injured mouse brain near a site of cerebral artery=20 occlusion, the cells enter into the injured area and express=20 neuronal and astrocytic protein markers [93<= /A>].=20 Similarly, when MSCs are injected intravenously into rats = that have=20 been subjected to traumatic brain injury, they migrate into = the=20 injured area [94<= /A>].=20 Of note, the rats that received BMCs showed reduced motor and = neurological defects compared with rats that did not receive = cells.=20 Although donor-derived cells in the brain parenchyma = expressed NeuN=20 or GFAP, suggesting that they may function as neuronal and = astrocytic=20 cells, these cells did not re-establish the normal tissue=20 cytoarchitecture [94<= /A>].=20 Therefore, it is unlikely that they were directly responsible = for the=20 functional outcome observed. More likely, the BMCs = facilitated tissue=20 repair by indirect means.

Under pathological conditions, circulating BMCs can enter the=20 brain and may actively participate in the renewal of CNS = tissue.=20 When middle cerebral artery occlusion was performed on mice=20 that had been transplanted previously with GFP+ marrow=20 cells, donor-derived cells appeared in the injured tissue = within=20 3 days of the ischemic injury [95<= /A>].=20 Donor-derived endothelial cells (assessed by colocalization = of GFP=20 and the endothelial markers Willebrand factor, CD31, and IB4 = lectin)=20 were present, thereby suggesting that BM may facilitate = tissue repair=20 by contributing to neovascularization. By days 7=9614 = post-injury,=20 BM-derived cells expressing NeuN were found in the ischemic = zone [95<= /A>].=20

Human MSCs also differentiate into cells with markers of = astrocytes,=20 oligodendroglia, and neurons after direct injection into rats = that have undergone cerebral infarction. As with = administration=20 of murine MSCs, mice receiving human MSCs show functional = improvement=20 even though the human MSCs did not establish new neuronal = circuits=20 with the host, again suggesting that these cells facilitate=20 functional restoration indirectly [10= 9].=20

BMCs have been tested for their ability to repair spinal cord=20 damage in a rat model of demyelinization, in which = oligodendrocytes=20 that maintain myelination are destroyed by local injection of = ethidium bromide followed by X-irradiation. Administration of = BMCs, either directly into the lesion or intravenously, was=20 associated with remyelinization of the neuronal axons, and = the=20 conduction velocity of the remyelinated axons was increased = [96<= /A>,97<= /A>].=20 However, the derivation of the new myelin-forming cells from = the=20 donor BMCs was only assessed by the cellular morphology of = the donor=20 cells in the areas of remyelination. It cannot be ruled out = that the=20 BMCs indirectly enhanced remyelinization of the axon fiber by = improving the recovery of endogenous myelin-forming cells. = These=20 results are consistent with those carried out by others [98<= /A>,99<= /A>].=20 For example, injection of MSCs into injured spinal cords of=20 paraplegic rats was associated with improved recovery of the=20 paraplegic animals, even though the MSCs did not show = significant=20 differentiation into neuronal-like cells [10= 0].=20 Taken together, these data suggest an important new concept: = Even=20 though MSCs are not able to replace damaged neuronal tissue = in the=20 spinal cord, they may be useful as accessory cells to = facilitate=20 healing, perhaps by producing trophic factors, cytokines, or = other=20 restorative factors.

Most of the in vivo studies demonstrating plasticity of BMCs = into=20 neuronal-lineage cells, in rodents as well as in humans, are = based on=20 the coexpression of donor-derived markers (Y chromosome or = GFP) and=20 one or more neuronal or glial proteins. However, there are = several=20 concerns regarding the specificity of the antibodies used, as = well as=20 technical problems related to microscopic detection of single = cells=20 expressing multiple fluorescent-labeled markers [78<= /A>,10= 1].=20 In some cases, the neuronal protein expression pattern was = supported=20 by specific neuronal morphology in vivo [50<= /A>,90<= /A>].=20 However, even if BMCs can be induced by their local = micro-environment=20 to express specific neuronal genes and assume a specific = morphology,=20 the functionality, such as the capacity to integrate into the = neuronal transmission network, has not been shown. Data are=20 consistent with BM-derived cells providing a "neuroprotective = effect"=20 on the existing cells, perhaps by activating endogenous = healing=20 mechanisms=97including revascularization.

Even though definitive scientific evidence that BMCs can be = used=20 to treat CNS dysfunction is lacking, doctors have started to = use=20 BM-derived cells to treat patients. To date, data from a = single phase=20 I trial have been published. In this trial, patients with the = severe=20 neurodegenerative disease amyotrophic lateral sclerosis (ALS) = were=20 injected intrathecally with BMCs. After 6=9612 months, none = of the=20 patients had side effects, yet significant clinical efficacy = was not=20 shown [10= 2].=20 Related studies are under way in several clinical = centers.=20


3D"    CURRENT CHALLENGES IN PLASTICITY STUDIES
Top
Abstract
Stem Cells in Adult...
Evidence for Bone Marrow...
3D"Current Challenges in=20 Plasticity...
Lack of Reproducibility of...
Discussion
References
 
<= STRONG>Cell=96Cell=20 Fusion
Reports of in vitro and in vivo cell=96cell fusion = suggest=20 that somatic cell fusion may be misleading scientists to = conclude=20 that there are stem cells in the bone marrow that are more=20 pluripotent than previously believed [52<= /A>,=20 53<= /A>,=20 10= 3,=20 10= 4].=20 For example, when BMCs from a female mouse that was = transgenic for=20 both GFP and puromycin resistance genes were cocultured with = a male=20 embryonic stem cell line on gelatin-coated plates,=20 puromycin-resistant clones developed that were = morphologically=20 similar to embryonic stem cells and could be induced to = differentiate=20 into cardiac myocytes and neuronal cells. This had initially=20 suggested that the donor-derived BMCs had differentiated into = embryonic stem cells. However, when DNA ploidy was analyzed, = the=20 cells were tetraploid (n =3D 11) or hexaploid = (n =3D 2),=20 suggesting that they had resulted from spontaneous fusion = between the=20 BMCs and embryonic stem cells [10= 3].=20 As described in the previous section on differentiation from = BM to=20 liver in FAH-deficient mice, wild-type BM-derived cells can = take on=20 the phenotype and function of hepatocytes by cell-cell fusion = [10= 3,10= 4].=20 Thus, it is possible that some or all of the in vivo = differentiation=20 that has been referred to as BMC plasticity may be due to = fusion of=20 differentiated BM-derived hematopoietic cells, perhaps = macrophages,=20 with mature tissue-specific cells. This issue was addressed = in vivo=20 using mice with normal liver function and the Cre/lox system. = Stoplox-=DF-gal transgenic mice that contain lacZ = downstream of=20 stop codons flanked by loxP sites were lethally irradiated = and=20 injected intraperitoneally with BMCs from mice that = ubiquitously=20 express Cre recombinase and GFP [91<= /A>].=20 If a cell from the donor and recipient fused, then the Cre = enzyme=20 would permanently remove the Lox P=96flanked DNA, allowing = expression=20 of the lacZ gene. =DF-gal+ (fused), = GFP+=20 cells were found in the brain, heart, and liver of BMT = recipients 2=20 and 4 months post-transplantation. Importantly, no = GFP+,=20 =DF-gal=96 cells were found in recipient tissue, = and the=20 hematopoietic compartment was largely reconstituted with = donor cells.=20 In a second experiment, donor mice expressed Cre recombinase = from the=20 CD45 locus, so that cells that express CD45, or once = expressed CD45,=20 also express Cre recombinase. These cells were used as donors = for BMT=20 into stoplox-=DF-gal reporter mice. Ten months = post-transplant, all=20 four BMT recipients had =DF-gal+ hepatocytes, half = had=20 =DF-gal+ cardiomyocytes, and one mouse had = =DF-gal+=20 Purkinje cells [91<= /A>].=20 Thus, BMC engraftment into these tissues is at least in part, = if not=20 entirely, due to fusion.


3D"    LACK OF REPRODUCIBILITY OF FINDINGS
Top
Abstract
Stem Cells in Adult...
Evidence for Bone Marrow...
Current Challenges in Plasticity...
3D"Lack of = Reproducibility=20 of...
Discussion
References
 
S= everal=20 reports in which BM-derived cells do not differentiate into=20 epithelial or neural cells have called into question the = validity of=20 the initial findings. For example, Castro et al. [10= 5]=20 failed to detect marrow-derived, neuronal-like cells, or = microglial=20 cells in the brains of lethally irradiated mice that received = bone=20 marrow from ROSA26 mice with a lacZ-containing = transgene.=20 There are many possible explanations for the disparate = findings. For=20 example, because the experiments were not performed using = identical=20 mice and detection techniques as those in which BM to = epithelial=20 engraftment occurred, the data could be due to false negative = findings, because ROSA26 transgenic mice show transgene = instability=20 in several tissues, and =DF-gal detection is sensitive to = fixation and=20 staining conditions.

Wagers et al. [50<= /A>]=20 failed to reproduce the results obtained in single-cell=20 transplantation assay by Krause et al. [49<= /A>].=20 Despite differences in the donor cell population used, they = did=20 show a very low frequency of liver cells (1/6.7 x 104) and Purkinje = cells=20 (1/1.3 x 107) that were = derived=20 from a single KTLS BMC.

Need for Accurate and Sensitive = Techniques
Technical=20 problems still persist and can be misleading. Most of the in = vivo and=20 in vitro work establishing plasticity of BMCs is based on the = coexpression of donor cell markers (e.g., Y chromosome FISH,=20 GFP-expressing cells, and =DF-gal-expressing cells). When = samples are=20 analyzed using stringent conditions and proper controls, = techniques=20 such as immunohistochemistry, immunofluorescence, and FISH = can be=20 very revealing. Optimal methods for costaining individual = cells are=20 still being established, and false positive results can be a = serious=20 problem. When possible, all results should be verified using=20 alternative approaches.


3D"    DISCUSSION
Top
Abstract
Stem Cells in Adult...
Evidence for Bone Marrow...
Current Challenges in Plasticity...
Lack of Reproducibility of...
3D"Discussion
References
 
P= ublications=20 on the potential plasticity of BMCs are significant and = exciting, yet=20 there are several questions that need to be answered before = these=20 cells can be considered to have therapeutic relevance. The = biological=20 mechanisms for BMC plasticity are at the center of an open = debate,=20 with multiple hypotheses being proposed for this = plasticity:=20

  • BMCs could be the source of specific stem cells present in = different=20 tissues. Data showing that BMCs give rise to oval cells, = satellite=20 cells, and type II pneumocytes support this hypothesis. =
  • Fusion could explain why BM-derived cells are able to = take=20 on diverse tissue phenotypes. Even though fusion = alone=20 is unlikely to underlie all of the plasticity = data, it=20 cannot be ruled out that, under selective = pressure such=20 as acute organ damage, BM-derived cells may fuse = with=20 other cell types.
  • BMCs could be genetically reprogrammed when they are=20 exposed to a different microenvironment. This = phenomenon=20 has been described as "transdifferentiation."=20 Transdifferentiation occurs in fish and amphibians, = and=20 nuclear reprogramming can occur in mammalian = cells under=20 certain experimental conditions [10= 6].=20 However, no study to date has demonstrated that=20 transdifferentiation underlies adult stem cell = plasticity.=20
  • Finally, a truly pluripotent stem cell may persist through=20 adulthood. This hypothesis is supported by the = findings of=20 Jiang et al. [82<= /A>],=20 who demonstrate that MAPCs contribute to most cell = types=20 when injected into the blastocyst. =

An essential area of future investigation is clonality studies,=20 showing that a single, well-characterized marrow-derived cell = gives rise to mature, functional cells of multiple tissues. = We=20 need to understand at a single-cell level what part BMCs play = in the=20 cell turnover of various organs in normal and diseased states = and the=20 biological events that guide these phenomena. It is hoped = that in the=20 near future we will begin to characterize plastic BM-derived = stem=20 cells in the rigorous manner that hematopoietic stem cells = have been=20 characterized. At the same time, studies on epigenetics will = help us=20 determine what commitment means at a nuclear level. =

Most of the collected data, showing that BMCs give rise to = different=20 tissue-specific cells, are based on immunohistochemistry and = on=20 visible morphological changes of the engrafted cells. This = approach,=20 as discussed above, could be insufficient for assessing = plasticity.=20 Even when BMCs are shown to express specific genes and modify = their=20 shape, the functionality and integration into the host = tissue-network=20 are not guaranteed. Nevertheless, there are some reports that = unequivocally demonstrate that BMCs can engraft in = non-hematopoietic=20 tissues, integrate into the host tissue, and work together = with=20 endogenous cells. This is the case of the reprogrammed = BM-derived=20 hepatocytes described by Lagasse et al. [51<= /A>],=20 and the BMC-derived myocardial cells described by Orlic et = al. [10= 7].=20 In addition, the fact that a boy transplanted with allogeneic = bone=20 marrow displays an unexpectedly mild form of muscular = dystrophy=20 contributes to our belief that BMCs may help ameliorate = pathological=20 conditions in vivo [11= 0].=20 This important therapeutic effect need not be due to = unexpected=20 levels of bone marrow plasticity. For example, various = studies=20 show that administration of BMCs can stabilize CNS disease by = stimulating the activity of the endogenous cells instead of = by=20 replacing the damaged tissue [98<= /A>,10= 0].=20

It is important to note that, even though the basic science=20 surrounding BMC plasticity is at an early stage and lacks = conclusive=20 scientific evidence, clinical trials using BMCs have started=20 for some diseases that are particularly difficult to treat=20 effectively. We now proceed with a balance of caution and = excitement.=20 On the one hand, when possible, adequate preclinical studies=20 must be performed to assess safety and efficacy before human=20 trials proceed. On the other hand, patients are of course = anxious=20 to know whether this will work in humans. Currently, several=20 centers are conducting clinical trials to assess whether=20 administration of marrow-derived cells to patients following=20 myocardial infarction can lead to improved outcome. Despite = promising=20 clinical outcomes, as of this writing, no randomized = controlled=20 trials have been published.

In conclusion, scientists need to make an effort to understand = the=20 biological mechanism(s) of BMC plasticity and to characterize, = or=20 give an "identity" to, plastic BM subpopulation(s). At the = same time,=20 researchers need to ask themselves whether these phenomena, = even if=20 they do not occur physiologically, can be manipulated for = therapeutic=20 use.


3D"    REFERENCES
Top
Abstract
Stem Cells in Adult...
Evidence for Bone Marrow...
Current Challenges in Plasticity...
Lack of Reproducibility of...
Discussion
3D"References
&nb= sp;

  1. Kondo M, Wagers AJ, Manz MG et al. Biology of = hematopoietic stem=20 cells and progenitors: implications for clinical application. Annu Rev = Immunol=20 2003;21:759=96806.[CrossRef]<= /A>[Medline]

  2. Prockop DJ. Marrow stromal cells as stem cells for=20 nonhematopoietic tissues. Science 1997;276:71=9674.[Abstract/Free Full Text]

  3. Pittenger MF, Mackay Am, Beck SC et al. Multilineage = potential of=20 adult human mesenchymal stem cells. Science 1999;284:143=96147.[Abstract/Free Full Text]

  4. Jiang Y, Vaessen B, Lenvik T et al. Multipotent = progenitor cells=20 can be isolated from postnatal murine bone marrow, muscle, and brain. = Exp=20 Hematol 2002;30:896=96904.[CrossRef][Medline]

  5. Mauro A. Satellite cells of muscle skeletal fibers. J = Biophys=20 Biochem 1961;9:493=96495.

  6. Moss FP, Lebond CP. Satellite cells as the source of = nuclei in=20 muscles of growing rats. Anat Rec 1971;170:421=96435.[CrossRef][Medline]

  7. Campion DR. The muscle satellite cell: a review. Int Rev = Cytol=20 1984;87:225=96251.[Medline]

  8. Ferrari G, Cusella-De Angelis G, Coletta M et al. Muscle = regeneration by bone marrow-derived myogenic progenitors. Science=20 1998;279:1528=961530.[Abstract/Free Full Text]

  9. Bittner RE, Schofer C, Weipoltshammer K et al. = Recruitment of=20 bone-marrow-derived cells by skeletal and cardiac muscle in adult = dystrophic=20 mdx mice. Anat Embryol (Berl) 1999;199:391=96396.[CrossRef][Medline]

  10. Gussoni E, Ssoneoka Y, Strickland CD et al. Dystrophin = expression=20 in the mdx mouse restored by stem cell transplantation. Nature=20 1999;401:390=96394.[CrossRef][Medline]

  11. Ferrari G, Stornaiuolo A, Mavillo F. Failure to correct = murine=20 muscular dystrophy. Nature 2001;411:1014=961015.[CrossRef][Medline]

  12. Goodell MA, Brose K, Paradis G et al. Isolation and = functional=20 properties of murine hematopoietic stem cells that are replicating in = vivo. J=20 Exp Med 1996;183:1797=961806.[Abstract/Free Full Text]

  13. Jackson KA, Majka SM, Wang H et al. Regeneration of = ischemic=20 cardiac muscle and vascular endothelium by adult stem cells. J Clin = Invest=20 2001;107:1395=961402.[Abstract/Free Full Text]

  14. Welm B, Behbod F, Goodell MA et al. Isolation and=20 characterization of functional mammary gland stem cells. Cell Prolif=20 2003;36(suppl 1):17=9632.

  15. Ferrari G, Mavilio F. Myogenic stem cells from the bone = marrow: a=20 therapeutic alternative for muscular dystrophy? Neuromuscul Disord=20 2002;12(suppl 1):S7=96S10.

  16. LeBarge MA, Blau HM. Biological progression from adult = bone=20 marrow to mononucleate muscle stem cell to multinucleate muscle fiber = in=20 response to injury. Cell 2002;111:589=96601.[CrossRef][Medline]

  17. Brazelton TR, Nystrom M, Blau HM. Significant = differences among=20 skeletal muscles in the incorporation of bone marrow-derived cells. = Dev Biol=20 2003;262:64=9674.[CrossRef][Medline]

  18. Corbel SY, Lee A, Yi L et al. Contribution of = hematopoietic stem=20 cells to skeletal muscle. Nat Med 2003;9:1528=961532.[CrossRef][Medline]

  19. Ye M, Iwasaki H, Laiosa CV et al. Hematopoietic stem = cells=20 expressing the myeloid lysozyme gene retain long-term, multilineage=20 repopulation potential. Immunity 2003;19:689=96699.[CrossRef][Medline]

  20. Orlic D, Kajstura J, Chimenti S et al. Mobilized bone = marrow=20 cells repair the infarcted heart, improving function and survival. = Proc Natl=20 Acad Sci U S A 2001;98:10344=9610349.[Abstract/Free Full Text]

  21. Fuchs S, Satler LF, Kornowski R et al. Catheter-based = autologous=20 bone marrow myocardial injection in no-option patients with advanced = coronary=20 artery disease: a feasibility study. J Am Coll Cardiol = 2003;41:1721=961724.[Abstract/Free Full Text]

  22. Perin EC, Dohmann HF, Borojevic R et al. = Transendocardial,=20 autologous bone marrow cell transplantation for severe, chronic = ischemic heart=20 failure. Circulation 2003;107:2294=962302.[CrossRef][Medline]

  23. Petersen BE, Bowen WC, Patrene KD et al. Bone marrow as = a=20 potential source of hepatic oval cells. Science = 1999;284:1168=961170.[Abstract/Free Full Text]

  24. Tomita S, Li RKI, Weisel RD et al. Autologous = transplantation of=20 bone marrow cells improves damaged heart function. Circulation = 1999;100:II=20 247=96II 256.

  25. Makino S, Fukuda K, Miyoshi S et al. Cardiomyocytes can = be=20 generated from marrow stromal cells in vitro. J Clin Invest = 1999;103:697=96705.[Abstract/Free Full Text]

  26. Pfeffer MA, Braunwald E. Ventricular remodeling after = myocardial=20 infarction. Circulation 1990;81:1161=961172.[Medline]

  27. Weisman HF, Bush DE, Mannisi JA et al. Cellular = mechanisms of=20 myocardial infarct expansion. Circulation 1988;78:186=96201.[Medline]

  28. Anversa P, Olivetti G, Meggs LG et al. Cardiac anatomy = and=20 ventricular loading after myocardial infarction. Circulation=20 1993;87:VII22=96VII27.

  29. Tomoda H, Aoki N. Bone marrow stimulation and left = ventricular=20 function in acute myocardial infarction. Clin Cardiol = 2003;26:455=96457.[Medline]

  30. Wang JS, Shum-Tim D, Galipeau J et al. Marrow stromal = cells for=20 cellular cardiomyoplasty: feasibility and potential clinical = advantages. J=20 Thorac Cardiovasc Surg 2000;120:999=961005.[Abstract/Free Full Text]

  31. Hayry P, Aavik E, Savolainen H. Mechanisms of chronic = rejection.=20 Transplant Proc 1999;31:5S=968S.[Medline]

  32. Orosz C, Pelletier RP. Chronic remodeling pathology in = grafts.=20 Curr Opin Immunol 1997;9:676=96680.[CrossRef][Medline]

  33. Wu GD, Nolta JA, Jin YS et al. Migration of mesenchymal = stem=20 cells to heart allografts during chronic rejection. Transplantation=20 2003;75:679=96685.[Medline]

  34. Kocher AA, Schuster MD, Szabols MJ et al. = Neovascularization of=20 ischemic myocardium by human bone-marrow-derived angioblasts prevents=20 cardiomyocyte apoptosis, reduces remodeling and improves cardiac = function. Nat=20 Med 2001;7:430=96436.[CrossRef][Medline]

  35. Quaini F, Urbanek K, Beltrami AP et al. Chimerism of = the=20 transplanted heart. N Engl J Med 2002;346:5=9615.[Abstract/Free Full Text]

  36. Deb A, Wang S, Skelding KA et al. Bone marrow-derived=20 cardiomyocytes are present in adult human heart: a study of = gender-mismatched=20 bone marrow transplantation patients. Circulation = 2003;107:1247=961249.[CrossRef][Medline]

  37. Pagani FD, DerSimonian H, Zawadzka A et al. Autologous = skeletal=20 myoblasts transplanted to ischemia-damaged myocardium in humans: = histological=20 analysis of cell survival and differentiation. J Am Coll Cardiol=20 2003;41:879=96888.[Abstract/Free Full Text]

  38. Assmus B, Schachinger V, Teupe C et al. Transplantation = of=20 progenitor cells and regeneration enhancement in acute myocardial = infarction=20 (TOPCARE-AMI). Circulation 2002;106:3009=963017.[CrossRef][Medline]

  39. Hamano K, Nishida M, Hirata K et al. Local implantation = of=20 autologous bone marrow cells for therapeutic angiogenesis in patients = with=20 ischemic heart disease: clinical trial and preliminary results. Jpn = Circ J=20 2001;65:845=96847.[CrossRef][Medline]

  40. Stamm C, Westphal B, Kleine HD et al. Autologous = bone-marrow=20 stem-cell transplantation for myocardial regeneration. Lancet = 2003;361:45=9646.[CrossRef][Medline]

  41. Strauer B, Brehm M, Zeus T et al. Repair of infarcted = myocardium=20 by autologous intracoronary mononuclear bone marrow cell = transplantation in=20 humans. Circulation 2002;106:1913=961918.[CrossRef][Medline]

  42. Tateishi-Yuyama E, Matsubara H, Murohara T et al. = Therapeutic=20 angiogenesis for patients with limb ischaemia by autologous = transplantation of=20 bone-marrow cells: a pilot study and a randomised controlled trial. = Lancet=20 2002;360:427=96435.[CrossRef][Medline]

  43. Forrester JS, Price MJ, Makkar RR. Stem cell repair of = infarcted=20 myocardium: an overview for clinicians. Circulation = 2003;108:1139=961145.[CrossRef][Medline]

  44. Theise ND, Saxena R, Portmann BC et al. The canals of = Hering and=20 hepatic stem cells in humans. Hepatology 1999;30:1425=961433.[CrossRef][Medline]

  45. Theise ND, Nimmakayalu M, Gardner R et al. Liver from = bone marrow=20 in humans. Hepatology 2000;32:11=9616.[CrossRef][Medline]

  46. Alison MR, Poulsom R, Jeffery R et al. Hepatocytes from = non-hepatic adult stem cells. Nature 2000;406:257.[CrossRef][Medline]

  47. Danet GH, Luongo JL, Butler G et al. C1qRp defines a = new human=20 stem cell population with hematopoietic and hepatic potential. Proc = Natl Acad=20 Sci U S A 2002;99:10441=9610445.[Abstract/Free Full Text]

  48. Wang X, Ge S, McNamara G et al. Albumin-expressing=20 hepatocyte-like cells develop in the livers of immune-deficient mice = that=20 received transplants of highly purified human hematopoietic stem = cells. Blood=20 2003;101:4201=964208.[Abstract/Free Full Text]

  49. Krause DS, Theise ND, Collector MI et al. Multi-organ,=20 multi-lineage engraftment by a single bone marrow-derived stem cell. = Cell=20 2001;105:369=96377.[CrossRef][Medline]

  50. Wagers AJ, Sherwood RI, Christensen JL et al. Little = evidence for=20 developmental plasticity of adult hematopoietic stem cells. Science=20 2002;297:2256=962259.[Abstract/Free Full Text]

  51. Lagasse E, Connors H, Al-Dhalimy M et al. Purified = hematopoietic=20 stem cells can differentiate into hepatocytes in vivo. Nat Med=20 2000;6:1229=961234.[CrossRef][Medline]

  52. Vassilopoulos G, Wang PR, Russell DW. Transplanted bone = marrow=20 regenerates liver by cell fusion. Nature 2003;422:901=96904.[CrossRef][Medline]

  53. Wang X, Willenbring H, Akkari Y et al. Cell fusion is = the=20 principal source of bone-marrow-derived hepatocytes. Nature = 2003;422:897=96901.[CrossRef][Medline]

  54. Kanazawa Y, Verma IM. Little evidence of bone = marrow-derived=20 hepatocytes in the replacement of injured liver. Proc Natl Acad Sci U = S A=20 2003;100:11850=9611853.[Abstract/Free Full Text]

  55. Schwartz RE, Reyes M, Koodie L et al. Multipotent adult = progenitor cells from bone marrow differentiate into functional=20 hepatocyte-like cells. J Clin Invest 2002;109:1291=961302.[Abstract/Free Full Text]

  56. Oshima H, Rochat A, Kedzia C et al. Morphogenesis and = renewal of=20 hair follicles from adult multipotent stem cells. Cell = 2001;104:233=96245.[CrossRef][Medline]

  57. Taylor G, Lehrer MS, Jensen PJ et al. Involvement of = follicular=20 stem cells in forming not only the follicle but also the epidermis. = Cell=20 2000;102:451=96461.[CrossRef][Medline]

  58. Korbling M, Katz RL, Khanna A et al. Hepatocytes and = epithelial=20 cells of donor origin in recipients of peripheral-blood stem cells. N = Engl J=20 Med 2002;346:738=96746.[Abstract/Free Full Text]

  59. Hematti P, Sloand EM, Carvallo CA et al. Absence of = donor-derived=20 keratinocyte stem cells in skin tissues cultured from patients after = mobilized=20 peripheral blood hematopoietic stem cell transplantation. Exp Hematol=20 2002;30:943=96949.[CrossRef][Medline]

  60. Cheng H, LeBlond CP. Origin, differentiation and = renewal of the=20 four main epithelial cell types in the mouse small intestine. Am J = Anat=20 1974;141:537=96562.[CrossRef][Medline]

  61. Simon TC, Gordan JI. Intestinal epithelial cell = differentiation:=20 new insights from mice, flies and nematodes. Curr Opin Genet Dev=20 1995;5:577=96586.[CrossRef][Medline]

  62. Bjerknes M, Cheng H. Clonal analysis of mouse = intestinal=20 epithelial progenitors. Gasteroenterology 1999;116:7=9614.[CrossRef][Medline]

  63. Okamoto R, Yajimi T, Yamazaki M et al. Damaged = epithelia=20 regenerated by bone marrow-derived cells in the human gastrointestinal = tract.=20 Nat Med 2002;8:1011=961017.[CrossRef][Medline]

  64. Brittan M, Hunt T, Jeffery R et al. Bone marrow = derivation of=20 pericryptal myofibroblasts in the mouse and human small intestine and = colon.=20 Gut 2002;50:752=96757.[Abstract/Free Full Text]

  65. Mason RJ, Williams MC, Moses HL et al. Stem cells in = lung=20 development, disease, and therapy. Am J Respir Cell Mol Biol = 1997;16:355=96363.[Medline]

  66. Theise ND, Henegariu O, Grove J et al. Radiation = pneumonitis in=20 mice: a severe injury model for pneumocyte engraftment from bone = marrow. Exp=20 Hematol 2002;30:1333=961338.[CrossRef][Medline]

  67. Kotton DN, Ma BY, Cardoso WV et al. Bone marrow-derived = cells as=20 progenitors of lung alveolar epithelium. Development = 2001;128:5181=965188.

  68. Ortiz LA, Gambelli F, McBride C et al. Mesenchymal stem = cell=20 engraftment in lung is enhanced in response to bleomycin exposure and=20 ameliorates its fibrotic effects. Proc Natl Acad Sci U S A = 2003;100:8407=968411.[Abstract/Free Full Text]

  69. Kleeberger W, Versmold A, Rothamel T et al. Increased = chimerism=20 of bronchial and alveolar epithelium in human lung allografts = undergoing=20 chronic injury. Am J Pathol 2003;162:1487=961495.[Abstract/Free Full Text]

  70. Davies JC, Potter M, Bush A et al. Bone marrow stem = cells do not=20 repopulate the healthy upper respiratory tract. Pediatr Pulmonol=20 2002;34:251=96256.[CrossRef][Medline]

  71. Ianus A, Holz GG, Theise ND et al. In vivo derivation = of=20 glucose-competent pancreatic endocrine cells from bone marrow without = evidence=20 of cell fusion. J Clin Invest 2003;111:843=96850.[Abstract/Free Full Text]

  72. Hess D, Li, L, Martin M et al. Bone marrow-derived stem = cells=20 initiate pancreatic regeneration. Nat Biotechnol = 2003;21:763=96770.[CrossRef][Medline]

  73. Poulsom R, Forbes SJ, Hodivala-Dilke K et al. Bone = marrow=20 contributes to renal parenchymal turnover and regeneration. J Pathol=20 2001;195:229=96235.[CrossRef][Medline]

  74. Kale S, Karihaloo A, Clark PR et al. Bone marrow stem = cells=20 contribute to repair of the ischemically injured renal tubule. J Clin = Invest=20 2003;112:42=9649.[Abstract/Free Full Text]

  75. Perry VH, Gordon S. Macrophages and microglia in the = nervous=20 system. Trends Neurosci 1988;11:273=96277.[CrossRef][Medline]

  76. Eglitis M, Mezey E. Hematopoietic cells differentiate = into both=20 microglia and macroglia in the brains of adult mice. Proc Natl Acad = Sci U S A=20 1997;94:4080=964085.[Abstract/Free Full Text]

  77. Gage F. Mammalian neural stem cells. Science = 2000;287:1433=961438.[Abstract/Free Full Text]

  78. Rakic P. Neurogenesis in adult primate neocortex: an = evaluation=20 of the evidence. Nat Rev Neurosci 2002;3:65=9671.[Medline]

  79. Deng W, Obrocka M, Fischer I et al. In vitro = differentiation of=20 human marrow stromal cells into early progenitors of neural cells by=20 conditions that increase intracellular cyclic AMP. Biochem Biophys Res = Commun=20 2001;282:148=96152.[CrossRef][Medline]

  80. Sanchez-Ramos J, Song S, Cardozo-Pelaez F et al. Adult = bone=20 marrow stromal cells differentiate into neural cells in vitro. Exp = Neurol=20 2000;164:247=96256.[CrossRef][Medline]

  81. Kim B, Seo JH, Bubien JK et al. Differentiation of = adult bone=20 marrow stem cells into neuroprogenitor cells in vitro. Neuroreport=20 2002;13:1185=961188.[CrossRef][Medline]

  82. Jiang Y, Jahagirdar BN, Reinhardt RL et al. = Pluripotency of=20 mesenchymal stem cells derived from adult marrow. Nature = 2002;418:41=9649.[CrossRef][Medline]

  83. Hao HN, Zhao J, Thomas RL et al. Fetal human = hematopoietic stem=20 cells can differentiate sequentially into neural stem cells and then=20 astrocytes in vitro. J Hematother Stem Cell Res 2003;12:23=9632.[CrossRef][Medline]

  84. Kopen G, Prockop D, Phinney D. Marrow stromal cells = migrate=20 throughout forebrain and cerebellum, and they differentiate into = astrocytes=20 after injection into neonatal mouse brains. Proc Natl Acad Sci U S A=20 1999;96:10711=9610716.[Abstract/Free Full Text]

  85. Mezey E, Key S, Vogelsang G et al. Transplanted bone = marrow=20 generates new neurons in human brains. Proc Natl Acad Sci U S A=20 2003;100:1364=961369.[Abstract/Free Full Text]

  86. Mezey E, Chandross KJ, Harta G et al. Turning blood = into brain:=20 cells bearing neuronal antigens generated in vivo from bone marrow. = Science=20 2000;290:1779=961782.[Abstract/Free Full Text]

  87. Brazelton T, Rossi FM, Keshet GI et al. From marrow to = brain:=20 expression of neuronal phenotypes in adult mice. Science = 2000;290:1775=961779.[Abstract/Free Full Text]

  88. Corti S, Locatelli F, Donadoni C et al. Neuroectodermal = and=20 microglial differentiation of bone marrow cells in the mouse spinal = cord and=20 sensory ganglia. J Neurosci Res 2002;70:721=96733.[CrossRef][Medline]

  89. Bonilla S, Alarcon P, Villaverde R et al. = Haematopoietic=20 progenitor cells from adult bone marrow differentiate into cells that = express=20 oligodendroglial antigens in the neonatal mouse brain. Eur J Neurosci=20 2002;15:575=96582.[CrossRef][Medline]

  90. Priller J, Persons DA, Klett FF et al. Neogenesis of = cerebellar=20 Purkinje neurons from gene-marked bone marrow cells in vivo. J Cell = Biol=20 2001;155:733=96738.[Abstract/Free Full Text]

  91. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM et al. = Fusion of=20 bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and=20 hepatocytes. Nature 2003;425:968=96973.[CrossRef][Medline]

  92. Weimann JM, Johansson CB, Trejo A et al. Stable = reprogrammed=20 heterokaryons form spontaneously in Purkinje neurons after bone marrow = transplantation. Nat Cell Biol 2003;5:959=96966.[CrossRef][Medline]

  93. Li Y, Chopp M, Chen J et al. Intrastriatal = transplantation of=20 bone marrow nonhematopoietic cells improves functional recovery after = stroke=20 in adult mice. J Cereb Blood Flow Metab 2000;20:1311=961319.[CrossRef][Medline]

  94. Mahmood A, Lu, D, Wang L et al. Treatment of traumatic = brain=20 injury in female rats with intravenous administration of bone marrow = stromal=20 cells. Neuro-surgery 2001;49:1196=961203.[Medline]

  95. Hess D, Hill WD, Martin-Studdard A et al. Bone marrow = as a source=20 of endothelial cells and NeuN-expressing cells after stroke. Stroke=20 2002;33:1362=961368.[Abstract/Free Full Text]

  96. Akiyama Y, Radtke C, Kocsis J. Remyelination of the rat = spinal=20 cord by transplantation of identified bone marrow stromal cells. J = Neurosci=20 2002;22:6623=966630.[Abstract/Free Full Text]

  97. Sasaki M, Honmou O, Akiyama Y et al. Transplantation of = an=20 acutely isolated bone marrow fraction repairs demyelinated adult rat = spinal=20 cord axons. Glia 2001;35:26=9634.[CrossRef][Medline]

  98. Chopp M, Zhang XH, Li Y et al. Spinal cord injury in = rat:=20 treatment with bone marrow stromal cell transplantation. Neuroreport=20 2000;11:3001=963005.[Medline]

  99. Ishii K, Toda M, Nakai Y et al. Increase of = oligodendrocyte=20 progenitor cells after spinal cord injury. J Neurosci Res = 2001;65:500=96507.[CrossRef][Medline]

  100. Hofstetter C, Schwarz EJ, Hess D et al. Marrow stromal = cells=20 form guiding strands in the injured spinal cord and promote recovery. = Proc=20 Natl Acad Sci U S A 2002;99:2199=962204.[Abstract/Free Full Text]

  101. Svendsen C, Bhattacharyya A, Tai Y. Neurons from stem = cells:=20 preventing an identity crisis. Nat Rev Neurosci 2001;2:831=96834.[Medline]

  102. Janson C, Ramesh TM, During MJ et al. Human = intrathecal=20 transplantation of peripheral blood stem cells in amyotrophic lateral=20 sclerosis. J Hematother Stem Cell Res 2001;10:913=96915.[CrossRef][Medline]

  103. Terada N, Hamazaki T, Oka M et al. Bone marrow cells = adopt the=20 phenotype of other cells by spontaneous cell fusion. Nature = 2002;416:542=96545.[CrossRef][Medline]

  104. Ying QL, Nichols J, Evans EP et al. Changing potency = by=20 spontaneous fusion. Nature 2002;416:545=96548.[CrossRef][Medline]

  105. Castro R, Jackson KA, Goodell MA et al. Failure of = bone marrow=20 cells to transdifferentiate into neural cells in vivo. Science = 2002;297:1299.[Free Full Text]

  106. Wilmut I, Schnieke AE, McWhir J et al. Viable = offspring derived=20 from fetal and adult mammalian cells. Nature 1997;385:810=96813.[CrossRef][Medline]

  107. Orlic D, Kajstura J, Chimenti S et al. Bone marrow = cells=20 regenerate infarcted myocardium. Nature 2001;410:701=96705.[CrossRef][Medline]

  108. Suratt BT, Cool CD, Serls AE et al. Human pulmonary = chimerism=20 after hematopoietic stem cell transplantation. Am J Rspir Crit Care = Med=20 2003;168:318=96322.[Abstract/Free Full Text]

  109. Zhao LR, Duan WM, Reyes M et al. Human bone marrow = stem cells=20 exhibit neural phenotypes and ameliorate neurological deficits after = grafting=20 into the ischemic brain of rats. Exp Neurol 2002;174:11=9620.[CrossRef][Medline]

  110. Gussoni E, Bennett RR, Muskiewicz KR et al. Long-term=20 persistence of donor nuclei in a duchenne muscular dystrophy patient = receiving=20 bone marrow transplantation. J Clin Invest 2002;110:807=96814.[Abstract/Free Full Text]

Received August 13, 2003; = accepted for publication January 30, 2004.


This article has been cited by other=20 articles:=20

3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Hum3D"Home
M. Mints, M. Jansson, B. Sadeghi, M. Westgren, M. = Uzunel, M.=20 Hassan, and J. Palmblad
Endometrial endothelial cells = are=20 derived from donor stem cells in a bone marrow transplant=20 recipient
Hum. Reprod., January 1, 2008; = 23(1): 139=20 - 143.
[= Abstract]=20 [Full= =20 Text] [PDF] =
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
F. Li, X. Wang, and C. Niyibizi
Distribution = of=20 Single-Cell Expanded Marrow Derived Progenitors in a Developing = Mouse=20 Model of Osteogenesis Imperfecta Following Systemic=20 Transplantation
Stem Cells, = December 1, 2007;=20 25(12): 3183 - 3193.
[Abstract]=20 [= Full=20 Text] [PDF]<= /A>=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Nephrol3D"Home
G. Stokman, J. C. Leemans, I. Stroo, I. Hoedemaeker, N. = Claessen,=20 G. J. D. Teske, J. J. Weening, and S. Florquin
Enhanced = mobilization of bone marrow cells does not ameliorate renal=20 fibrosis
Nephrol. Dial. Transplant.,=20 November 7, 2007; (2007) gfm607v1.
[Abs= tract]=20 [Full=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Hum3D"Home
K.E. Schwab and C.E. Gargett
Co-expression of = two=20 perivascular cell markers isolates mesenchymal stem-like cells = from human=20 endometrium
Hum. Reprod., November 1, 2007; = 22(11):=20 2903 - 2911.
[Abstract]=20 [Fu= ll=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
M.-S. Tsai, S.-M. Hwang, K.-D. Chen, Y.-S. Lee, L.-W. = Hsu, Y.-J.=20 Chang, C.-N. Wang, H.-H. Peng, Y.-L. Chang, A.-S. Chao, et=20 al.
Functional Network Analysis of the = Transcriptomes of=20 Mesenchymal Stem Cells Derived from Amniotic Fluid, Amniotic = Membrane,=20 Cord Blood, and Bone Marrow
Stem Cells,=20 October 1, 2007; 25(10): 2511 - 2523.
[Abstract]=20 [= Full=20 Text] [PDF]<= /A>=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
E. M. Bruscia, E. C. Ziegler, J. E. Price, S. Weiner, M. = E. Egan,=20 and D. S. Krause
Engraftment of Donor-Derived = Epithelial Cells=20 in Multiple Organs Following Bone Marrow Transplantation into = Newborn=20 Mice
Stem Cells, October 1, 2006; 24(10): = 2299 -=20 2308.
[Abstract]=20 [= Full=20 Text] [PDF]<= /A>=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Ann3D"Home
A Scherwath
Reply to 'Promotion of = neurogenesis by=20 human stem cells in high-risk breast cancer survivals after = stem-cell=20 supported high-dose therapy' by K. Altundag et al. (Ann Oncol = 2006; 17:=20 1465)
Ann. Onc., September 1, 2006; 17(9): = 1465 -=20 1466.
[F= ull=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
D. Bryder, D. J. Rossi, and I. L.=20 Weissman
Hematopoietic Stem Cells: The Paradigmatic=20 Tissue-Specific Stem Cell
Am. J. Pathol.,=20 August 1, 2006; 169(2): 338 - 346.
[Abstrac= t]=20 [Full=20 Text] [PDF] =
3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Am.3D"Home
T.-T. Sun
Altered phenotype of cultured = urothelial and=20 other stratified epithelial cells: implications for wound=20 healing
Am J Physiol Renal Physiol, = July 1, 2006;=20 291(1): F9 - F21.
[Ab= stract]=20 [Full=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
W. Huang, V. La Russa, A. Alzoubi, and P.=20 Schwarzenberger
Interleukin-17A: A T-Cell-Derived = Growth Factor=20 for Murine and Human Mesenchymal Stem Cells
Stem = Cells,=20 June 1, 2006; 24(6): 1512 - 1518.
[Abstract]=20 [F= ull=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
J. R. Harris, G. A. J. Brown, M. Jorgensen, S. Kaushal, = E. A.=20 Ellis, M. B. Grant, and E. W. Scott
Bone Marrow-Derived = Cells=20 Home to and Regenerate Retinal Pigment Epithelium after=20 Injury
Invest. Ophthalmol. Vis. Sci., = May 1, 2006;=20 47(5): 2108 - 2113.
[Abstract]=20 [Full = Text]=20 [PDF] =
3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"J.3D"Home
B. Hu, F. Unda, S. Bopp-Kuchler, L. Jimenez, X.J. Wang, = Y. Haikel,=20 S.L. Wang, and H. Lesot
Bone Marrow Cells Can Give Rise = to=20 Ameloblast-like Cells.
J. Dent. Res., = May 1, 2006;=20 85(5): 416 - 421.
[Abstr= act]=20 [Full=20 Text] [PDF] =
3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Circ.3D"Home
K. Fukuda and S. Yuasa
Stem cells as a source = of=20 regenerative cardiomyocytes.
Circ. Res.,=20 April 28, 2006; 98(8): 1002 - 1013.
[A= bstract]=20 [Full = Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Home
T. Chan-Ling, L. Baxter, A. Afzal, N. Sengupta, S. = Caballero, E.=20 Rosinova, and M. B. Grant
Hematopoietic Stem Cells = Provide=20 Repair Functions after Laser-Induced Bruch's Membrane Rupture = Model of=20 Choroidal Neovascularization
Am. J. Pathol.,=20 March 1, 2006; 168(3): 1031 - 1044.
[Abstra= ct]=20 [Full=20 Text] [PDF] =
3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Cancer3D"Home
N. C. Direkze, R. Jeffery, K. Hodivala-Dilke, T. Hunt, = R. J.=20 Playford, G. Elia, R. Poulsom, N. A. Wright, and M. R.=20 Alison
Bone Marrow-Derived Stromal Cells Express=20 Lineage-Related Messenger RNA Species
Cancer Res.,=20 February 1, 2006; 66(3): 1265 - 1269.
[Abstract]=20 [Fu= ll=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
X. Wang, S. Ge, I. Gonzalez, G. McNamara, C. B. = Rountree, K. K.=20 Xi, G. Huang, A. Bhushan, and G. M. Crooks
Formation of = Pancreatic Duct Epithelium from Bone Marrow During Neonatal=20 Development
Stem Cells, February 1, 2006; = 24(2): 307=20 - 314.
[Abstract]=20 [Fu= ll=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Hum3D"Home
M. A.F.V. Goncalves, A. A.F. de Vries, M. Holkers, M. = J.M. van de=20 Watering, I. van der Velde, G. P. van Nierop, D. Valerio, and S.=20 Knaan-Shanzer
Human mesenchymal stem cells ectopically=20 expressing full-length dystrophin can complement Duchenne muscular = dystrophy myotubes by cell fusion
Hum. Mol. Genet.,=20 January 15, 2006; 15(2): 213 - 221.
[Abs= tract]=20 [Full=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
J. Yu, M. A. Vodyanik, P. He, I. I. Slukvin, and J. A.=20 Thomson
Human Embryonic Stem Cells Reprogram Myeloid = Precursors=20 Following Cell-Cell Fusion
Stem Cells,=20 January 1, 2006; 24(1): 168 - 176.
[Abstract]=20 [Fu= ll=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Physiol.3D"Home
A. Leri, J. Kajstura, and P. Anversa
Cardiac = Stem Cells=20 and Mechanisms of Myocardial Regeneration
Physiol Rev, = October 1, 2005; 85(4): 1373 - 1416.
[Ab= stract]=20 [Full=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Pharmacol.3D"Home
J. C. Brodie and H. D. Humes
Stem Cell = Approaches for=20 the Treatment of Renal Failure
Pharmacol. Rev.,=20 September 1, 2005; 57(3): 299 - 313.
= [Abstract]=20 [Ful= l=20 Text] [PDF]= =20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Stem3D"Home
T. R. Brazelton and H. M. Blau
Optimizing = Techniques=20 for Tracking Transplanted Stem Cells In Vivo
Stem = Cells,=20 September 1, 2005; 23(9): 1251 - 1265.
[Abstract]=20 [F= ull=20 Text] [PDF]=20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Am.3D"Home
H. K. Haider and M. Ashraf
Bone marrow stem = cell=20 transplantation for cardiac repair
Am J Physiol Heart = Circ=20 Physiol, June 1, 2005; 288(6): H2557 - H2567.
= [Abstract]=20 [Ful= l=20 Text] [PDF]= =20
3D""=20=20 		3D""=20
3D""=20
 3D""=20 3D"Home
 3D""=20 3D"Am.3D"Home
A. M. Diehl
Recent Events in Alcoholic Liver = Disease V.=20 Effects of ethanol on liver regeneration
Am J Physiol=20 Gastrointest Liver Physiol, January 1, 2005; 288(1): G1 = - G6.=20
[Abstr= act]=20 [Full=20 Text] [PDF] =
3D""=20

This = Article
3D"
3D"Right Abs= tract=20 3D"Freely
3D"Right Full= =20 Text (PDF)
3D"Right Alert=20 me when this article is cited
3D"Right Alert=20 me if a correction is posted
3D"Right Citation Map
3D"
Services
3D"
3D"Right Similar=20 articles in this journal
3D"Right Similar=20 articles in PubMed
3D"Right Alert me=20 to new issues of the journal
3D"Right Download=20 to citation manager
3D"Right Reprints/= Permissions=20
3D"
Citing = Articles
3D"
3D"Right Citing=20 Articles via HighWire
3D"Right Citing Articles via Google = Scholar
3D"
Google = Scholar
3D"
3D"Right Articles by Grove, J. E. =
3D"Right Articles by Krause, D. S. =
3D"Right Search for Related Content =
3D"
PubMed
3D"
3D"Right PubMed=20 Citation
3D"Right Articles by Grove, J. E. =
3D"Right Articles by Krause, D. S.=20 =

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH SEARCH=20 RESULT
STEM = CELLS THE = ONCOLOGIST CME ALPHAMED=20 PRESS JOURNALS

------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/banner/title.gif R0lGODlh3AAsAOYAAP39/vr6+/j4+fX2+ODl7ubq8dvh6xsuSSM3VCk+XTNJaThObj1TdEJYeUde f0xjhFRqi1lvkF50lGN5mXaLqZurw7nF18HM3AkUIw4dMRQlPS1DYml/nm+Fo36SroaatZCjvKm4 zMrU4dTc5+zv8/v8/P////Ly8u7u7uvr6+bm5uLi4tzc3NLS0szMzMvLy8PDw7y8vLu7u7e3t7Cw sKqqqqCgoJmZmZWVlYiIiHx8fHd3d3Nzc2VlZVZWVkVFRTU1NScnJxYWFggICAAAAP///wAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH5 BAEAAEUALAAAAADcACwAAAf/gCaCg4SFhoeIiYqLjI2Oj5CRkpOUlZaXmJmam5ydlgAFBgCepKWm p6iUFhYEIyejqbGys7SWJB0XggMFJgMkJ7XBwsOnACTHASIPHyIkqwUjziLE1NXWkRUhJSUFyhQg IBIgFR8gDBK6sNfr7NQCEB+8BRS45BMVFRMQCA8mIhfR2gkcKItEAwggLoBIIGGCAggePkigoGBD BBEWApQwwMuRgBk8fgAB4iNHDRYEG5VYUUOHD5Eje/DAMWPFCQHqUnIKoSACCAoJJjBAAKECBwQO OEBY9mHEABEgCJRg9OLHkCBYgwwhMoSHzkQDZvgYMkSIkKxmiag9+wPG100n/wgUcAAxwYEHHThQ gNChgQQOGxKAWBDBg4QOIwoMMFFiBIETUwfBEEJEB0rGYon0eGvohQ+uJV/YNCFgxQscY9USqcEZ k4gQBUJsWKAhAwJ9EIA+AKFvwQYICjpYoEBBBEYTF1aFsADrBJDKhgYA2dxaUI0gRNpGRgTjsxC3 1SldcAACAAEHCjJg+H0AQYQOECaA4MBBwUELvCbITz4BKocQAlhHRBAqHIJaeDVs5UMKjQzwgxAv hEfJBwlQEII+DDjAwAMNIIDAXvZ54EADCSSwQQXGdSDCAAZMsMAHIYDQAQEmANBDdoi0kEN1LWD3 A4OOzBAEeBI+QkAECByQAP8CG5CIAAN1KfDBAwg04IEHFCxwwAEbLsAAbCEs8KSGDyxWwmc/bEcI AGrqdIJ3ET6SQltFPhJABArQloEGC3SQgAYN4OXQAxT4JSNwdiFQDl0dRMCBmEXBBkAA3hFZpwk0 bEWdnD3EGYwANvCQQ4GeFLBAAw5saWIHDywg1AIe8CXBYXgqkOSWFZgQAlK5GOCAB3JZAAwPavkQ 4CEtxNDCCsw26ywLL8AQg2grsMCsCizAAKQJJ7Rw7CLWNvIDVzFEIkALLEzLrLUrYCvaCzGwoEKy KwxSAgwwyNtCTYioQEMNNdAQgwog/ZADDqSQMNSSHHRQEVEUJOnBYAk4QIH/Ugz8qcEBHhTggQYM gPDPAw5UMNwIJiSoFg85CSLAuGcFMdLMWAGhlQ84wPTDDzJr5ekLQHiayMsIL9LCVkIAIwkLOY+0 c89CxFCDDzPr0MIgAkzttNWH0GDzS1vpgAMNP9RQtCcfbKmAAhgMoYEGD0iQAANYhviXB/VteQAE EEQgQQMMHGTXA4Tz4pxqPCg9SI89BEwDDTpwlcPjLQWhgwk2qCXw4zoEcZkJMBDh1SKh77gIDmql WUnmROAQA+dDoJQCZT20bMILtCMSwxA+sFBCtz/0EIPYOphOCkV/YlBbe3pR8AEHDJTTgH0UbKAk AgkogLIICzxgQJgSw6Jy/7GkCkJDDjnBUNbnmO74AleKm5DD1YLMQIQQ7B/yGcuL3KiZJS/YitB6 cJnnXM4QKnjO2Qphs3oNogY8yBoOcODAUlRgSxnYEwIyoI8DNOADH5iYA7LnovYsCQIrAgAHIrC9 CHxgMYPIwVbUErRBpCB+JphBWYSWgquFbgjlMwELFFeDlSmiBZTxQQAWMS7RWQKJRCjXIIYoiP0d YgUKvOIQVDcI08iiBAvAgKoiMMIKdABkjbrHB1xVqCRtACkVMMAIWvUBC3wgV4UoQQ5UMyAaJEKH EDrED4NYiD0OqIKGIFZ2cGiI5xDBeJOAohQNYUVDYLF1yBoCELZViwAsIP+DXArMMg4AKBAshQNX +kkDNoYADTBkLxAIwQc0NA1DAECGqhGCHw8BSKFJhiuEJAQPgkAZSBKiR5/Z5CIceUBKSBIRlSzE JReINco0MxgRG5x6FlCBVnWgAxt4SKAkYCtVbaw9C7BALyTwgTYRggbYWcskCdFLQQITEZT6AbGC gMhBdM5+QuhnI9VSu0pA0VKEiCYhpokI/6FPGKYi5QQQgAFUOSACCYhVAuijjxKpzUMOmEAE4kiA EMAwETBwJBGAkL8c7tCeQ9gWAFqgtBP8wAdQpKYJViAEHfCUCC0tRBN/sERnUsZSNK2iEy2ZxUOw gDJdYWQsQNAekWaAbwv/sEsDOuA8DziqL3pDgAdIYAILyKccjWCBSq9Zv5caInTZ8YFcSaK0FARh M/vkpPzwRwLszPMQisSfQSlz07n6QGkK7WJTeUkZIvQuGBdY22z2tkIQYLQBHNCPTyKSKgRwk6wF ANyXHNEjGvaznm8lKA960AMhFNQEKujK7bYCyRPc1QQkeA5rFFFEtej0EVD0wWpbayyljk6ai+1a Y1laCwB84I1vY5V7INAnBTjAjl6VzxhDMALZQECdj1DZdwqB2kL8UHHng8UKMBmAGwVhWzgIpE0f uYifrpSskTzqIGaQg6ImVhAMVQTQUqfXWFzgARs7jAIeEBgIcOADFuLA/0HC9LYGREAfH7DdIl5G LvK61bz3FEQPIxO6ou1uCDZwGRBU117oKMJGahnCbxvxTBGzABb/3WlyEbGCJs4YFdlEgH28NIG4 cYCdEgHhRLe0gQ1wQKrcKvAgiDWEv5aXEINEhA2GsFsAjOsHwKBB1Kb8v0UEUC1BoB9p3VJjSi4V uZhkxCWVWQsLKGBJQs7LYUTEgQo4QAMToEAEEOxKDVDABDLIgUkIYYMfR2689PwwlkNsiD3uModq mUEJdqaOyP2AEQCIXOqgbEuxmaDNhchxgBkB0KCmwgIPFoEHKibSQFPAMBu6NaFJ+YGU5WAHKHCB P9lKiBvReb+S/iUQEf/BA0ibIABf1uFuBYG6IDRiTqrpgZQNkVs/ojqhb17ojgXxAhySwCyunkUB HhCBCDBAPn+BR/X0Jiuy1mAHwBa2IHTARWlih9iZC2RqY7qmF0zFB0JQM6a4IrP4Ze69aVXpD3xp oEDC1VIloN9zjisZtYa7Rix4LCFsC/FqCODIgZbAAzIrgQ0wQEnRG8EHDIDoHNzgBoTYo04FYOwC oy7hMGXfCXoQoAaOvIkpfuf9KM5j/91PBzDQ8AlsIAQgACMGXLHU0EeBnU0JogSdeo7XYasDIFDT fsSuRXc/INKkOCBuJDpAngiHWQigDBF7HEIPYEDWsHwmCEyP3BBmcAj/1vVgWStoQQ98wK2z6FWH JZdM2B4x9XjeryQ1kBYMapCDJjI+ZcVCvOI/fQLKCMEG1Up8SCZzPxqwwFot8EEPHkR4QcRAZgKd BQAim2AHVAl7mB1Me6zXHgl8yxC3j3HMaNdSUAGBLD/AwecE4DWyXGUkWsnBC1rrWoyXxBAzMIsQ eFADUkvTBg/i41ZmyHC31OD5ZJGZzYaQAxa0lixVx/4We2D9/M9f0WVBEj4QBCI3DAMAYREAER4C HC4UASEwawqQIRPREYmQAhBENdMxPxoWAPCCLzGgLYMQAMmCLzAwAyY4A9qyAh8oLfmTAkVFCAOQ AioQA9NyfIxQGi2xnXhOIxOuozQjiC8niIInkAIrKC1BSIIwEC0xcIQkUAIvkAOslQMx4E7B8AHW tRR2kRQUIAFQ8gAJECggcClieCkD4AFxsw8NMD12ERgMYCsOQHNjGIcSMgokQDgTUCLZ4yUWABty 2IdFYgELcGe+4QBTkgt+eIjVMQAVMGjUtQAQcF2IGInV0RgUEDcVgF+SmIk6UQIs0oSa+ImnEAgA Ow== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: application/octet-stream Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/adsystem/graphics/1200244325145/stemcells/pts_blinks_bnnr_ani.gif?ad=16034&adview=true R0lGODlh1AE8ANUAAO/v5eTZ1uLXuevZi+vSbf/WCO7SSdjNoMzMzO/OMffOGc3DwdS/dsK9s929 St69Ib2xgbKupc6uT7KplM6mIbGiXaWciq2VKpaOe4eEb5pyMXRjKlpaMVJCGTo6IXMQUv4BAgAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACH/C05FVFNDQVBFMi4wAwEAAAAh+QQE BgD/ACwAAAAA1AE8AAAG/8CCcEgsGo/IpHLJbDqf0Kh0Sq1ar9isdsvter/gsHhMLpvP6LR6zW67 3/C4fE6v2+/4vH7P7/v/gIGCg4SFhoeIiYqLjI2Oj5CRkpOUlZaXmJmam5ydnp+goaKjpKVbCqip qFipUqter6wKX7FDrWa1Y7liu0i3tqrBYL1axI4PyMnIWMlSy10Kz1fRD1/SQ81l1GfIs2XXStnY yuRg3bTgkeTiVexO6azwrvJX6e5h22bn39VN7uvKzD3wBo1eI4D9rNxjYpBKvmkNqdiLWIyiln1k KFJLKAShRWcD0XGUtFDhx3GwTiZ5yGXiSHwqTRIcE7EckZLWQqZ8CQmnxP+YMdGw3BLUEEaaPIvY HJc00FB1RZP4RBJVW1WpTXvqzJi1Y8CbV+U81doVZFkjYXmlRXuW0VExFv+tfTP20VSzIPXUrdd2 0dswccHd7bP34FyvfYVQm1knGeN4Wyv9Ffn4iNzEeRxLpofwyMavRD7P/MyRNFuC4oYCrAxWsy1l lUWHXlqAXWcjGzcuUb2ONW7YbGnPdt2a6WvQWEcODk7OtNLIq08bR3xUtmXienB6LEL68lLnBbor l4aR97olzZkKr00bPHuO24efV2J+vefez+e3Fi4utf38AJrlkVwzIcQYRv0BRx1yC0aGh3aO6bYf f91ISB1qFWKXDUvmoYL/3W9HRXiZh9coiNh+JI4H0G6CZThZfinml15rMRZ3onq+TacjFLCJZqFX BTrGIILS5Ebjj+G5iNkaECZk3o4shTgehqU9w2GLVLJYJXzQ6cRbcDYmqeKO901J5nXHPZdlmuME mZBc77S45HtseqVmmARCeU2UXb45ZxpN1nkjnYJKeeegdhKqGJZncrdniV1682WAgz6JaJmHKoqV oOytuSiXbpIZmIqzGAPmp2BlqmieiF4JKp5/ohEoqrBuCVaQmeZZHaOXgjjcrcCK+dyplcrZ6K/B akqVk7xqymeol44q43+U8qlqgma2+uirOh4mEIOKWuospLgme1mnyLZ5/6ygzwY7aZjhGturo9kq iyat6mrL7aBw+iMnfugVCem15DXLjqvJrhorN+v5N6a+CRss51C8eerLthF72SKx8T5sL7251sRs vQeTW+uw/pL6aVkOp5qxnyRjXGifKO2hn47ilrwveyGP5J6w5jaEcL7z1gxvyyfTJzHLI/ecLrrd bpwydweK3LTRQCZNtM5PS7kwkxU+hnTUthLNc9AvCVfxuvgCnTXbLoWZs9BLR7E2xGZjizJDVufY sct5Fxxz2W3v6qDNnAnsMdeBOy0jY3d//HRuRh7XVNw4yys5p0Rixuq4O+sNeMBMH17twC+LuhXj K6dY9deAJn412V136f/4fr6iraV8MzLFGubFLk734Dx+zjrU/ErNd+l+j3124DDf7raYAKv3x6zT K0w48s+/bS+S2Xe+u+W9Hwv831pfTHwTP4s/M7TKSkt684qPzr3oW8u8cvmI+T0H9nPbnqF0x7G2 IW8qrvIf+LqHKOdpb3z5O8uKCFg4mkWrLXf5ELGslboLWiyBU+sDADV3vAFGEEQviRwC9aeltLmQ S7NLXldUaLVq0FCAFowfBjX3HvrFsFkPpOD0CkOp7MiOc4KrXblO+DiQCRFTnArHRDjmQPypT3pl 6scNlZg+BianiBo8HZcIFj0hDo19L6LDCIWHwyV67x5qq5vS2vhF+2n/qopJnCMWNyjHCsKvX8sD YxqDZz+vqe6DLEzjctywRkqV0HZPfA84tqjH99URaw2sXxdzx8RLUtKPXZTfjsIoN9RB75B6ouMV EXc5TdLOkph0H/l81sdVgjJf7xqlK2UIwTc2BI+IDF0eMXnJTJqulGPsoA6DycWo+e8NjUxfu2K5 OmMZbo9OvOXbcmlMJJZxJbW8TgwPmMgcApJ0gjxm5pJ5Sg+mspnJeyYjj2hAK04zUZ3M2vHIOcNy BklSytPlOK0IxXyKE4nMbKcO4+SxHqKzgmREJd60qTB5tiGar6RoOJ+xT1nacnpSAuh4qLjLIIJz fZ6s5T1Nis+Hzqx0/zOLqDsnClJzqlMOGOWlu4CYoNFYiYX85NuhLPW5btZTSCtEqS3P5b1tkhCI xbzRAsVYSJs+DEm8shQR43AbQk5oSBO0XoOeSpBPJgdmFLqZJI9WUvH0U6nLUmtX1cMgt8ookNMC Fx/Z2VSCxkeskqxrWDMzWAcGFo72sQ3/8GdW9cFwIWo1qle/Ojxs5lUw3REnZAdbNHjtbzDO4+kw 6eqOH0X2sBa9aGFLSr2P6TV8GpRlYz+61rgmhU8wjGIRC+pLCbpIKdRrpezAt9WF/CylfL3faFt3 j/qcNbWmiK5JYCfd6lr3ulNYJHa3y93uEku73g2veKWbm9eO97zolTEuZ9PL3vaOgjTQda9850vf +tr3vvjNr373y9/++ve/AA6wgAdM4AIb+MAITrCC1RAEACH5BAUGACAALB0ACwCaASsAAAb/QMVj SBwqQMikcslEEptQpPBxjFqjz6sWlN16QdNqsvstK8lm8/SRboe3RDG3SJe3oeg7M69/UP6Af2x6 IIBmfhSDhEuIi05/jnuCS4aRWo2WV4iKmU2bW4CcgaOJnUmTplyQloiknG2VX5+dmIu1mbOnq6mS FLyeqL9jwVahSqSBr5bEuLuOraPKZrFeuazOfdiR1oXav7fCqqXhj+NWraLIzMvmtN53rabUcOu2 74f32e3dvuTl/uWkpeLGJNqxerwQ2uu3bZ4jh5oUAozIsNm+iRgZSbQoUJcxjx0zLrRYMRLEcxtF aizZ8KJKjAR5xTz4EUnNl9dY6tNJ6CSW/5Q4xQ0EGtTUTKMbh9y8WZQQOKc+70QF5rLpMJ5Qq1qV SXRhSJA0v269lA/fPT7Fyi4RIkhskilnhryVG9cOxUR29bBNxIkMWix0o8CtO1SrrMBd9gaOsrTr mMVwqMT9auSxInR508SDoo7qqF7EoFUUvVJRrFuiNxq8Wg9a388eacJemWgqamRuxTFL7dJ1wV2n ZzMmxhQUbuE22+EuHTv5Td+gx21uoq4k75KdywUnRWmVgmC3kWV2Hiw7a0BiSDcnj/w6xTPqxp8P bd4j8ljbp/JLZ5hz9fvKLXeVacAlY18gvxk4XYJ8zVOdEt+1hZ525oSCDk0BXQWfhBKhM/9IhA3+ IYeF+QVYUTIL8sMdSqORmJKLLQooBYwjFsgQdGmZmJtsSsHYHX+1UZNLfnSB2CMFcmwST4oYllMj Q0KikksuERIY4z8aDrgeHs7MQqWUXTJDzXZPbknVhlZeUaWTWoIRpXTE2YimcTqmsd1VNfK35ZBh xjiINZUgshdW2+np3JziXAZeeX2y8Sai/LzX5pRg+tndibsAKieLkNpWqaIVNprhem+61Rhff12a ZaIHGRppm69iOaqm/SjpU6FNxsrqrrzyiV0p9Fl6KKeTLgqnsFviSmpZ4aXJ4p/GOjtrnFCKqsWp K15x56jJuVrqntbSGlBqCcIa67e9Rmv/ZijBdspsuOoKZa6uyg6r65mwenosqNLuKq69vOYI5Go5 rqqpt9bq2iy3r9qKXKz/KvwprL5eKuiG7mIlq7/xLpwrxNSa2UvGFEFrTsXFmghuf87xV4R+2wYc MsAob+zlzA4jqCrD+MF7crz3qrcqr/oi+u9gDNOb6cz3jpzvu/s+LWzE6Gob2mLF7SyvzCrTzOiV KfNXhVweKlPvuT7zK/Va7SVcdNhhcbnPmEt33fRKJGuiNrfoUp2wwFb3F/PBuVb9KNzzMrme31MD XbN9r3h8N8asHfnaO9zQfSPTb/OtlsVrI25v1YCXPtzmqKeDMLKHa2c5hBOydrq5PTf+//Pt/ZJn h+Sd60Zwy1S9ojntm/7E+ucz1vT4zXaTfvpXWedaC+HLHg82hQbKtiGhda9utONfg+a05xpv7Xv2 rNmVuTNn1y4p+dUQvPzE1UNqun+C102896HbrI7ZxuJe6gqXNoqFjzbjIxrU7Cc3lqwPUwOsH7Hg dy1X9I9jzfvb8wIHPf3xLIPWo1zSmmAk7czug9Wy3d4U6MDYDe1x+BqhZ5jzsfYVT255y1GIVtg3 zmkQfy4DS8FkRb3Rua1PDIQCiEyIP+Kl8Hu4uyB5InfE8kmOgwwcHgpFhjcpguYIlAqVCgmIrPvV JHqL616ryJhD8x2FOYqzF+OguEIYqv/IOlV8HwYFssR5aZFrT5wgC7GYLjHSkY3zAmLcgDfErRUR bSF8If2oA4k4ggyEh+QWDIXmP0MKknkdcd4f5/jJA56wkP0CJSJlmKAgMvKU04sT/yjYSZN1JGew 9OEYNWlK7CUpj6WM2rSiWEM1StB4baRkBAcpOkgmUZmu3E/gDCbLVTKzlltMlCVtGMhh1rGX/FiT JD2JTNGpMmmj1KUe7ai1MKZyks5MJDQXKc1GxjJAs7ymG+EZKA4J0Ikrs6UBydktiUWynN40p5jY Z0wjWhGYuSSmQQV6zIBtUIj1jOj+rDm/XQ4Ll03M5kR5aQ5xjrR1+ozhHt9SqfQsFIL/AAWYStkp PaD1EJPybGXGOoi6jVa0o5n8qD8jms9zFrQ51sBEGJPZi739y0FzY+gyVQSNdYKzqa/cTFL5OYkU AeU5/VTL4KpZ0YZVzahmRdJ1pEWrbLEHqjYaRZkKyVQGHQiuAJJqTdvhnmDmLjroW+ul2oaMwVYw qoWdJhHJ6tDB5jWFhP2MYOUYLLeebx8LsuAqeaeW6aQGgIHY3R8vKbzEIjSlypRfkHS2veLURzeH paJlQ+pIxsZzPvPwrGZl09X/pRGz6HEIjkToJqbUjLPl62Q9QNQbvf5WGU/oHU1hxyFF+S4vw62c cMW6DtHI57c+bSxtmBQehKBvLOhNSa88kKfe9rr3vfCNr3wnN9/62ve++M2vnW6o3/76978Ahi86 WBvgAhv4wAgWBnNdmOAGO/jBEDYeGiNM4QpbOL9r+O6FN4yTIAAAIfkEBQYAIAAsHQALAJoBKwAA Bv/AB2VIHD5AyKRyyUQSm1CkkHKMWqPPqxaU3XpB02qy+y0ryWbzlJJuh7dEMbdIl7eh6Dszrwdd /oB/fUiACmaCg3t/hoMUi4lMiEqAkHCPlVd/bJhWkpmeCoGiF5xJoRebpY4XjJCjnneFh6Sql32r rZiwfrulY7a+S5rBTb3FoK+UvqepnLi6r4myZca3wHfPpbvKxGfX3cPdk7RXq+Qgp8nBzMHZrtWx 35++7nr1ldvwzvLB4eKE56CIUpLunyl/+1hBCyiNXxR9dxTksudQzy6JE8VJNJgEoTiIAw9CxLSx XcVZDAdN+zKSI56TbVq65OgRXEphgQhym2lSIT7/mV5WBr3J08q9d0WTRkLlsuXOgkpr+XxHNN7U oVG9HG2YNWpNYk6RAe1aDibLkRijpBWKBONEIV/TLnlAN2MSO+joHim5RZMdt1b43l3VTIvcJoe1 4FWgF53dwILHsYm8BHAauEy1PN3Z5nDiuVA+56X7iUpl0QQnch5HarWTnNfMZX6d8xclOYQ7Sqon KFDhpYCayf7Nxbe32gDPUXJdXBPbJbxbB9dqHCevr8Mrc5smu2pynWMBXkc1ZDW7tr2n49wEdfzs 5tirX38YDXoy1SFpc+vu6YEk/7NFNwperCE0iiKiiNEdawUiZ9soj9GWSzIE2idKYfcBx1l73OVH /9857VGTjIfo+JPOheuhJwmKujkoxSibMHcdEatl+KIm5lRRHnkt0vieMrlJyJqPxI1B2CYAkgeI HMGtcsaRDPa4Y0AjRtjchDgG2Ql55uAEoxJJTikGh5fsOIRmYnknUJZNdilSKun4uBR7+0EJRpNL HifnfGteoOMfTK5oS5Ba8gJmOABaeMQqCgKDKETuEOoPgJs4OQ5wrP3pZ5TXWRkdkhBRSlugoAYk 6WxkXhUWiDJuSU42jL4pEjmchRNipOEUut2mMnbIqqBTWQpQM7DYulNuxzqaWYhN4Krcj5lFh2mL jAhbIrCeKksnSK8Wu2yyz8K5q6pqfjdrEWd1O/+VWOJiK5mK5zj7Lry6mXuMT9am2oq1BlL5bX+a nCekbtt6Jy/B80rrJWvVpkmtUdrSOw9tKV4brycmjovlUL8e2NdutrA768MIW3zcvhijumtybPkK Hq2DpkysvwUvjNCnEmMRc7gJKzttcg13TPJL5NY8cXMV3yrzyEBf+nHHX36ibisi5yyUsZ4cPCzT hrp3VacUc70Sv9AmXSMqgJ48L7MIosxzyQpzCjbSYleEs8lHW8uL0WFvbbXPT79caav2ulM13nP7 rXSwS//N8jUu18342+KtzdmCapfMtoVuz4s3gfk8i6/DTetcdM702WZ21o0jfnW5fBo5s5r7hfz/ a7swn474laqXnNxebc14ppdBvzw02TOvHlCSDN29eeZ0+23vMT/Pna/GEOv+vCnBR684uJ7r6zSa tH/FqeG3S44l37z3vbee1RPvvvju96u8hoU5T7izRdzcK0M7idzfvsY5y4XHW+xDnvrGJzXyFalF tqFa+ga4PtTxj0iHSpvc5Oc9+nnPfgZMSZ6g977dNWtnUevRmqonQNfZLWImtMIRavWvi1HOg10j nwMbOLAcXgt3Qyvh4tyWwnotrE/FW2D9yhZCBDUPhtvrIX9qMkLrHLF013OX6SoYQ6LRMIGtw+Gq duiqCBpRRUAs3fdYN7kiWmx2H0oiBXsnPR8K/3E1biIh1gy2Mwq4xS45WgoLy0S6xJ1Qe4Rr0Rct GEbsnZGHrnpg4WwHnjQaco/QI8wfmxAmCCJxfo78IBM1h8cq9vCO+tBaWUQIwJSNTmhqPCQXoygl BDLyhqG044euOCNIoq+SSlyjDTu3hSQx4n+vNJ4aFfhIVLbSI/pL5c5EJEhethCHbWti9jalN0zS sYQuJBfHrGk+T7bPhwITYw0zKZMgIVOO4SRmHW1pQuZlk5TSnJzn5pKPQSYzmLLU5pa+6czjhC+X Y5SbenbZw8OpE4z69N203glKLYoyeQLVDyyiyceI1nEpgfInPLFZQHx6p4UF/WbGLKrLPpHzPf/3 MmPl0AhQb0qxdQhiA0U7GEpmzlSYFuIFbqC4v2lKNFfeEmlFc5ctROoDpTa9aE1hR0PRSTJ2v5TV HE3KTlwKSqfVuGZPcUpPZi3Jf07tqDzBWcJuPpNhSw3iPYHqKnimdImWfN04FVrOSa5rgvHMqCpX CjOwEkWsFvWpHaMqKnDNsqgeZStS/aVUnrJ0rnf9pPcy61N17pWBC3VpQwH70FuulbAI22kWmarS Ud7pX0FNHEdXedrZiKo5IX2pXXOJ2ajea7frbG1eAadD+E1PtOd0KEKDe1PKxW4YhbAMFr2lkHRw MYvt2mesrDXb0vSMso8U2PRQurcpNfWx+TT/5089MtmFGWIl4mXopR6gAHNYCauU1Gpg4UXfPM4z WvkwRKzUQTK9eU1ZHoPr4zRoLi11Vy3IIXCDWPlX0dl1igTUI3O9SKJkYKg+DxIFfjK8wQOXq3Z/ BeZWF7yZcZFoiiy2sPtinAv+/GYazENIom40tYx6McQeyfGmOBg76/XiFef1cZ9chDYSwSe0r4UQ kZELZAbLN6s0XfGTXZRHG98rHBI28hMBxZbszHWG0PTHCB+cveN8Bc1bVC95p9zbDUMBzTsSRn0D QSAzW6jJX9tKiZ8MhsCNVsX7fZB/3edn4MDpj5TxQklQI+lSRFoPl05ELigtIhKb4r6caEWmVC1t mExzuhKjhkSqycLqVpPlMM9xtaxnTeta2/rWKgEWrnfN6177+tdROZKBgU3sYhv72Mi+yysqlOxm O/vZ0J5Jd64a7Wpb+9rYLqZemJ3tbu86CAAh+QQFBgAgACwdAAsAmgErAAAG/0DQZUgcgo7IpHKJ JCqY0KMxSq0On9Ws8ILVerdL4ncMvZLPzQt6Pc2KkYqiXL2mxul1qjmPpGj+gH8UfIAPY34ag3xK F3+GfI0aj4t9gkqAlFqRk5lQiHidTIiKVYCkD4GpiaFHqBqgnZuZiKqka4WHlqGykI6so5d/rFG8 w0qfxkvAWaZIrqq6oa6wmcV8tKm2aLhfy7G+vZK/0UeYyYzg50fI6uvkUc2t0PHSf9SU1nm0rNxe 3tXp6uRb9A+EuXZCAp5j167gkmzO6KmbZmzgmn2h+mlxyEfBA04CFRJ89xHkOY8mkzFUxzEJRHnv zn3sskvkxYOZNGZpiVCTTf99MXsKVWavJ89ygU5JHMrKIhqMnXRWOcqUidM6VKs2LIqQKgVaSoNq DZfyKU5KUqlkHSvlJ1axbLe+MgrXZbRn2uLmuUoGqrKvKMuCKGlQZEmTkS5oCyyKwqSvtr4meSAZ JU1PkZgcjoLSqr3IkvsAJgyFMOSdtigPsjym5GUQn1iXJn0sNGzbCV/lfXh36UbJtGknwX17kPBW uE+vy7xkc5SZlYRBARTp1evqrwLGCcSlSapgXO3COVjsU9JS3OFg747uLHYNduEjoU79On23uR/b O+/zLOz9/oGwXX2THcTNe8z0Vtd02VGXm3UFzgXTesdw9cx86R0xoD2vFcb/lV/gpULNPJy8J+GD 0iH1nV10MFQeiVSI6J2MIUaDIIbyqUhjfKkIll90qvTHnzvQgGQiKBeq+MiNMSq4ChnzqIJkeM+s GB0dSXoY3pG8nQdifEQAQpOJAVFXXRKJ4WEmczhiiGY6tISZYxmJgXmmneHl1oaHdlZHU5Q+vmjP ECk2Keec2AypIqGFZtlPmgk+OZhvkR56aBcUwfQKo6CwkyWneBaqJ6P/iRrfjLYYWOachXrDUJ7M sfkjkWqeWMaq4rHYFqLv4EReNAqoKg4xcIaXpygpRkLKq7YWlqumOOonaZOS4nXGr8MWFhYejv7R hac4WVOoqOYgUuqc4C3p/2S0qNIa3bIWniVduMVKmOWt2Srr7r6CauMrOPpCq6Qe9WIZ4HC6BFyq wYUGzFC32a5FT5JD7MYEto94k+mkKfYDbsPpOExluYJ8yW5uYeX4qC4MuRovua9sPOvCAhObL8vh sdMvePGpW62wgRZcsycJR/PxnCKfCLG0FoOX8o7UzpixgtwCfeXQxSRdtXSjJJrtwChH1HHIOJ/o sr3yCiKqoAyjGwbZT7bM1c6nnqzw0gRH/LLbFT6p8NFvxj3y2HpPC4+TUkYqNZHbiq2y0BwjDbci D5OciNcgHbgu2GHTzPjVkbcn68yA5z2J1qDT3abdm3sYdOFtT1W0pKXvSv/54I8X3nR8Kd/mJ3o5 8qIx7id7fm/WZW8tX9eqZA5w6ysLbrbRe3e5NuT3enaz9MqLhrDh/w57t9U2Sxu7WrPDizbI3Dte vMTA7unh7nzuOvXPSpNvPL3b326rOaqhzJouozn85e50yXsX6LKnJViwbWjaQ2D7cGSxgoTPZ73j XAQXeDBnfAWDHGSf/7rHOfgZrkv3qNushpc/wpkPa5Pb165gYTKwjc+F7fJcqdR3Ph69DXYQ/KEE i3Csg1lwXM8zYPE2uC8GWoF665PcBENXwgWpiH4Oipr9Pjch91UxioEbopxgcZYaus52XjwjGnV4 th7OyG0PpGL53gi1YB3/i4ursyH08BNHJ9qMdtXLYeVwiEdqYfGOPNviDsVGQjXuj30STFzgOtXB AmbQkajDY+1UuLgmdlCRKMoQkPJyRFYl8ZJp6eQj+cYgemwyk3L0mBXnB7wU5lF4VEujLMGoSjI1 615mtKQuY8hGKLoxj6rcJBNRdpgHdMg/pezZGmPJR+x9UkMm4iEMp4i3Qh7uhOCxpYo6ycJG7tKN yINPM5+ZomCecpj9k2Ebg3inMIaQlb2cZWFo2Cskim+PXxPiPd2Aib8Fco2DPKACI5WqaGTxm+TM Zc3OuU0J0o9I4nDnP5XIOVjOU444gqM1TdUei3pBYYvkpDAnWk0ggrSV/9N8ZQJZqjstSIQeD4Wp IssJzxeCNJ0XxZAaNApCmpq0mIDkJY8cOFJ8ghKWvKEk+PxZVGoGtKQDzZsiDKrUziX0fbO8qUMR qUJc4s+cTbUnQsnqIQUQdZrd9GrOjBnEVIwpraYTJFtlFU3WcdSRy1Rml6oqU27qz4QNlVROL5Ys cPDUqFl96kwZdK5vVjWuHqXrSxNDjj5eE6jynBsU/UVVuOovsAdtJWFTC8u4IpZ3OBJn/VYoUav6 9HjE/OrC3to52+p1ekk9pimu51I/5nOKOhttIvX411SCUrDpiilrJ+vasJIDp2wd505rW92uglaH SfoEb2+o0LUCV5sv5f8Q/2772dzOVUJcJa0pN4rKlrKXpNLsbWFH2NOFAs8WCrvmbM3aOMh6EpK/ JaF4K/lOAyPFf99Dr8y0hUm8zhFDENaVfvs536rO1rmkSy1j6RvZB+Oxu0GViKwoVVbHcvew0/1a 2RJpLlo0M78oxcUzfHrDrbUIVtJRmGfx69/kSsqOdIgEpopY2t6Oqjqvu69TO+fKD+XJyIl1jI0Z aVNyIMMQIB6wi8/aX2iBuVVohm9nfaEsr42VxHQMBCfm0Z6NWkm7+0ymiJsTiJD2OXCi3FW2LjhN Hck5rweespaG5Ga30RnQPQK0j2jJo0DrlLZkdvCi/6yp3N3Z0MJoNCntVorRSFfabVsGNRlPhLES 42u+AapF3wbdZJSG0r6u1t5L/mOi1wTJeocG0qR9UyTFbTfTvj01cWFN0huJ2q/aqE6qfcigEi3W Wbe0cN5CZDPFVBuZpNYQZOx4VbWusj8bPrNYON0lwCJl2EGxNESPXeBkv3G2M+I2EzY0mWZ+ZA3/ HkzAz+CRUHSmEwM3OCeOsw38HLwnj5CNOgpeBYZryOLScOZEJq2Xjnv84wKfRJhBTvKSm/zkKE/5 tQin8pa7/OUwjzlb0lQnmdv85jjPuc5bye6d+/znQA96XD4t9KIb/ehIxwpxks50mQcBACH5BAUG ACAALB0ACwCaASsAAAb/QApoSBwKi8ikkvhYLo9Hp3TanFqZ16xxq+16q95wNEyGdqNg5ZisTLOv 7jdoQ6/T5cN6+I5X8vt/fUWBeYSCToaHfhuKVomLjIN2k42SlZaKk3p4m12PnJGAoY2GnZdJn5ep latEpnOar5mjrLSgmqK2jrqih61kpb++vKfCgr8Xr7Gyw6eFpMZZzFPRWtWIxHLB2bXOi96o3LDK 12/l0uKe59jpSOtOcdrtXu+C8eD16rvk84f3vbP6XZkmJR84WMUEHlyIkGHDgnbcGXRITSFEixf3 YKQ4USLFjxA5tuMH0lvHcbUUnkzIsqRLVxs1oqNF8KW5mOHE/YN05mGR/39r1DihUGUnEQ10LgS1 ck9INKNlhhYlE+/O1FNORxKqiZXN0qNJv8KRRGxZHKS4fqKloyENJSLJIkq8MOSBqa2a6F4M9GDt hraQNuiFeTeQ2SRrUVaUOGnwFL+OC71F0tcOYLKEybYiqTHvJDd4J2kIh1kyX7+XGf/NvGTZ6CJx 04IVrTlUbLmsYb1+VruO2HGB/LLNyc+wcU27h9zGjU21nd+E60Q+XET46tKKTYvjTG8ZbUzR7Uwf 1WkyCOvJtQuWzI7RWrfUQVDY5Ht28jqjpZeO65Fs/qQVXScffXSMQWByaKVX2B3v9caVT+P8t16A 5xUnXhHz8VFfbqYkOP9QaMAMB9k48DE2WmLgZRchERlGsuEQHhJY1h9oMZYbCPzB5Bheu3XIR40p 6nZja6PkWMhgGQa5DXZA1lXeZjQJ+CCNPBoxHFzG7fgHOTPZ2NlsSkYZSh0lDhmIkbBoOeYGWc1I nphmvtmfjnGyFyZ2zaWI151e2skbh1DOqSKRfPr5J4RPRtklWZF9KCdMgmbHZZ16wskbQYX1Oemh iL6pqJCFDvpNpYLu2aeKIBpKaKXbPQoppZwmGik7zuHnKKlhrvmpqqbGuqWL5hma6qBZhkoSgMYG iuurvuaE57BT7ioqacweummnus5KpJiyZVRtr35ee61P0ALLnLCWEuv/arND1lhgpMftUmqUPUqL 7rqSKvutvp3iSW6649LKKGFGZVottrCqO6+m5spiMKDSgvsvLctRu2+rC5e21JI3losxq/IeHO+y 4UoscF08UbgvvL9GLHGxhAXVCWjGMewyy/62KKDInoa8sr+zLpjrkKNeLBPIJOdr78lMb5u0x/Pa W3N1iWA6NcQZ8wz0hTgTbXEhrzWpnNXOdgwwvxN7IXbaT7esbcrexv0vy9kizXPYhLS4htX4ytp2 1Ii9qLXXdAdr1ycco2uzz9YaozPgbdd9cNNwM321r5I3LnUsgQ9bNuYJv9wzErEVrTnjwJ2r6uRC 85z5qkZfUbHdjS8e/yTln1ve99kub94tYWrqbvvPg68+LbjRzkVZEqV/fe/QxncdvVq/j0x8yUs7 rbLclyPM6+g8RxZHi0CbPXztydqylsy9oy5M87e3Dvr0xU+rWoXtR56w3KhCua7or7Meu241vYdh L2sDFBXX0ue+eawNQv3b3etMxzYnxOYIyMvg+SCoPbO16n++C53otGAkvkFPYfWrYHTS0y/CJWso AZOf9+zHQO7l73pKe1vuIriPv2FHXCOcHFmaYELXiVB6CrQDzSAXkqSdCoIyhNpiaFe5DN7shybr 4PO2N7cTAnFzt4ONhhDXPb/h0IpISFAwmJinM+4udwbM4RRjJzwqlv/RbWGsHA+5eMcNCrCF82tI EQMJRCQea0L1S54PE7hFQqLtj3C8IfqwlscdylCLfcSiJAE5wzG6yYsarCGkDgdGFybyiqwToBSb SEdMbvKOAdRKusbRqFNlkpKt5GS5CgjLG6EJWQmc1Lgg+bVfIjJJKdyjIz+Wy0iy0ZjB+96iqFjF N2rymWeCWcnoMshOhtKInGpSEOkXzFGQUjJlehYsT6TIZlqMO1dyYyynyRr41ZGRZrSTPXV5NvWo khbWCU2wcBNQA/3qPpsMTHhegZ77eTBIy2nn6QI0UM7VihAB5VYPL7ozV4ZKjgstTkgpZtFlqJM4 qvvdvWwliXpZk5zBK61asBrZP5RKVIXbGqh14qDS1DnMf8yzKB9fekCORlJ1PtWLSc2XRj0wA6k4 CsTjwjGYOBKzcw5NwlSDCr6aLs9Jj+zqE6SzNkbcpj3s2GdUP6iE5UBHcSnMJ/BkUdZpVAaYNpEC VL6QV74mhBt7PcVVwBFYvX6ksH1NrGIXe5AHMfaxkI2sZCdL2e05trKYzaxmN8vZYbCzo50NrWhH S1rR6kxwpU2talfLWpcsp5atja1sZ0tbL0ThrbXNrWSDAAAh+QQFBgAgACwdAAsAmgErAAAG/0CQ Zkgcgo7IpHKJJDKfTQ10Sr0YqViQVZrtRpdOr3i5HZuTw8v5fMWGo8Xi2q1Rz6Hle/LS6fv7dnN+ Y3wdgXpNfYhCiot7gEqDjlQajZN4fVyXTIWHUH6Hf6KGm0eZpYwdk4WjnmaSXp2blaqItKWySbCo aJa8SIWav1qQVAqguqPIpaelt46soq5ju1m5k8962avFSNW/28PBw8DdU8umyuaTzbO+eqyb31Xr tu9r4YvX6bXkqf5Hxvnbx0RaMlIA213KNyfepXlTCAL0whBevYkYH3UQ9ktipD+hLmZcVPGMQ3b3 6CEc2aVkQ5EsAQok5/GgOXQxHbkkBFFQyv+IMHP26sdtpVCMM8UF1cIqpNGjd3aKOemo55OaUI9I NYM1Ky6FHZfyczrNq5itXagqucBWzLGfUGjVmXqI7QUFwO7uKYtnA9wueJXIrds2L9+rbAPj0ZsX VdIzCuwaVjwYC06caRN7iXyIM2PESDwD80vULZmegyCSVnRvdYcNQ3fRUkRBoyZY2wqB+GP5jzDX sMHwju1rV+qfq2dT8qV7eBbXHJtjPgJ8CSzconobnd579/WUCln7CV5uozdLon7/Ia+xT3C1Ntdb V6bEtftEzr2LUkyh+Gv87WV3jm9I2PdfgL7M5h9R6rDHj4BxMadOFgq+E01+1I3i4Hf9VKj/HVmv qCPKhuadN8pa7XDYjoEO9pceMXANosFq85140BCwXEDaBly89ZoU7/gRWDe5jQdkiU8cuUEgfuAY ZCa0kKeje8IYp8iM1Yi4HFGs8OgdR0u8JcRqil3Y5EcbKXeQiaNR+eFBhz1hJI1OlhYelaShiCRu 3i1pYp31udlHZKj1URsIeYYmJAg+DmXHTPvcB4KLgXZQG2mH/lNecJRu6WhAd3JBS5nrWGlphnYO yqhVmoJ6YKdUFJOoq+RJqlUxSXGoUZxjwRliP7PqlkyV6Em4Z4LIIjRTozDCWNqat25XLFG0PNrO NTPtIotsxt72V6upWIukQEU+ZSp+TrE5/0W53j6rpx3VltfupzAS24+2YulH1ha88gOgqyHZq66r 8/4brbgCw8hWoR3eNC29kHaTrS8uKjmUbQMnmSzC8ka7K5rQhhsyq+xmzEkx8RKcccq5Plxev5cp s4Fin1iSTaRI6pfxxNRurLK6nZhZI7oj+1zvyx37qygg75SsdIQ9K3ttM+V6cu7BRbt7cdI6A4VQ ykc/LXLYT+P7lJwOKwPm0B4DPGzWGIu9Dct31hK0jSGD3fXeY0e8Es+VhuM030zMjevUB1YN8sB6 67putyaf9rXEKRrd8r3Gwpx2HVawuvfNDifMN+AG9103wEIvPnbZliMeCOnx0Tw4ya3nvP8oU6Sa uyDRA9POZeVaI7067Kbb7rLbb0YB4oAN94Oz6GYX3DbWZO/dFitvMJ72yoePS/mxz8q39c+ECxc1 xyaWRdDVq+/te9zlkxEI2MTTbTzmv59d0FJnMm/w83DjGrfORz5EgQU+2pMW/iDmOgG+w0fPmt23 DPcjLOVMPzQTXsawo8DICQZyYsOCAkjzOuAx8H47yxd3bhQrm1kCgL0DId8oyCMLcqQaCHxa445X PE1gy4SViqAM34efUdwQLMjboAs7GELzwc9zaCoh+E4IvcxlYYV/amHzNPilAJJvgMQhUBJm5arg cTBdcuueD78nvYNkUILBm14qjKgnd63/b3fUY10cwUU8LbKRe1JDodi6kj4tri1vLwydF8kGxiK+ CE1rjNES0ThDNWqwj8564xAnmKwu+CFTSRTbGRdZuE3uEVUgcSABq+e4UNZMfyz03/RgqMcndrJ0 zBOXGSe5SPtFUoptRKUTVekp3hXzYyH73Paa+MH8BRNthiAhMXl3uRTCMoq+4schE8jF0w0SiHLU myxzqEwmVjKQv5ymTYb5RU6uEgvS5CLfRhnDPcJRO3msnyXriUwtLk8/29RhIqVVRWcCkl5uOAU5 6VlLajawnaVxka3kiMlmUrFm71JdOSlJRIj2Bl5/TCM6F0nIXhVSm1r8nyL5qU5w+fIJ/41aKC9Z Sj2/AdNkF7JoS0u5ysd8JFN3ZNBMGwo1W+6RofocKU0VdsW0MQmJqgMdQUkKTpfuk6cLk2TzOFq7 dHp0jO5pmimP2cOk0a9UeGxfKzVmUGYi8m9VfelSS6qvbAI0pbNcKVEZecuaejMYMt1qL6/6wymu SSH3fFxPESeq71ktrTtcoGKNitfhxfWq7rNi8kx6V1m2ipaZbes5Lwq0TATWmKElLVO/eoSKjXan 7Czrz86qO6EKdqk8paxnadtGue6VrpjpRv9eqdKpzvWyixUkYBmG2rX6lpYWgkQjWctW1XaRj2i1 rTF9hBdmFRW2UQ3pOdH3WxWaA2xYFP+o8/Sa2pZSkLzMWu4DE8jVtu6QWFwz4KnAllhMwLVEO0zG R46o3Tymg0c0mix4P+UjKW4qbpFVg1qgWqO60Matb+2mIAn3yTn2k1xo9ZiZhDtU/eJtVcrIICwM lCq72aq/r6wFBP9AMxaxTZQl1g+Eqrvg8rTCxwZZ2ihqPCGNQrMzDcJnXo27Vx3vWMdHmPHtTETj Ea+Eoc56spk8cRKJjicJLuIUB3Wr2PUGGQlevgdV2Kc3vNBHwdRlgpt/DCoDSS6VYC6yjzcbLVGA EprFDRgprdxMM+M5NE6WgpWfetsCHedZ0SjLPYbrKiEfCsZQIGOkMSrpAqvXFZLpKF9zT5kOC5bw QVc5dHvU9BE+95nU6tVwQc23kW9oWtVgtUQGEb2GXZvl1zmBIkZ8DWxGFfvYyE62sn+17GY7+9nQ jvZEJOFdaVv72tjOdrajZEEHafvb4A63uFny5nGb+9zoTvcdnqzudrv73eqWDLzn3ewgAAAh+QQF BgAgACweAAsAmQEqAAAG/8CNcCgEGY/IpPI4XDqZm6d0CipSr9ar1piFRrfgZTdMHpPBZmcTSWx/ z9M0XCmf26eUu55rzN+/fnuCgoCDWIaISIGJTn5vhoWMiIuShyCUZ5GVm1KanHyfepicjoyeoXCj qGx9eqernK+bj7BPGkuqlaWJsrVXubC9aK2+n8KmxWTAjLuIx8m40EkUy1rPg9TV2NqQ0lvchtSS 197E5YPk5+px61Lg7U/p3u/waub1+Oz5ivuZ9/v0+oEKKFAarXwE98nblisbv2kOk3w5eElcIzCL LFLpYOQWRI24Rk3ECPKjnYz0Itor+THhyDMJlahU+Y2lNo4gPCqiKZMgTv8QP5/gBEcRlJGgrOxd UhJUp6Utj5wWnfITKZ0jwF419bfEapiGRufEPBK0g4aq04z68Xp1aSdoSJ0+PMqUiRO5Qo1caDu2 LdC6U/aGhRP3Yrx/cA7ijYbEalCwVUR9eqz2rhjEEskCfrulw1S2Iini9CwG5+KOfNXgnFqFLRfW Vb6UPQqbbG2ZnFVtWK2F9DAxFCH/BXobtx7ftINXpj36sls2rmNT2a1HMB67zp1YTxI9NVV9gYoe fIlo+5OsmLkH1r4xqV/hkhNRst7snSxN4sMNfm48cvbcXGGSDn5KJbWQcQfB511SLh3GH3bvnYfN EbfUMV16br2hoH8imZP/H4bf7Cfch+B10uGDHFrjYYHYHZiWf3P155yAIHI243/ubSiWE90pBZmG EmaGYor7LfeLYQkGCaOQJV4hFWIDroijfy4+lKRhPi4YxlT3FahjKg7+9iNWSmJ3YnhehsjYlYwt 6R6AXRX5SpTPkailMiKWeSeRZTh4YoRYxkflHMLUpyefDELIJDiqNEMmlnb6aZmkQnJDYHZ9ISnj i1lWmhilTC56qB0WihkkkIEOdGORbj4UXh2OYojmlKt+l6inlszqlySxDgninDU+2quZtML4JS9b ymrkpogSyypFxSHI7KOtsorrFHIB6+uCsgnBG4Xy5Znqtc6S4VqXmI6K/4ypmipLbrndUlftjq2O yCKom+1Jp66hvnmSuG3WWi4Y0aELaMCzJLutoeOiy6+/zeFZr5KRdrrEac1mbHHFR5gH5sTj3iqy FhgPrGiO6iLL7prUMuvwySc/fCTIbXK8Z6431/qFBtmwlJN+NE9rssZ5XTgkicc6o/CY7o4Mb0c9 Z/oim/3Z/K6KKO4LM2c9UtFr0tqC07XGSKes9MrSNj00n9GCQB9GAFd9r8VSZAtlsKpay6MgX5sd Nsn9Ov1sy5zGsvSphMeY97VtD6om1ZxaLXicgms9uBRjI1745lengxSXmJUd8rpQuYsqwmRLuWt8 kM8l+dpG07gt43Nrxv+60LP/Dfe8qac7usqlL7ws5y9fXqw7cUdee862b6d77Fu3St6/QXNeOd5W 4hv96bifHTzTwl/NdprHp62468uLj4Rgjzzf5Lzj6f047uhljf2joB9NPurjHN5u+JO71MECp7nz Uet1iyuW++AEv7Y07n+Ji+DQDjSsBG5PgrMzV5iwBr4NFa+B6YlW3yCVPrflrUezkp2lVBe4l3hs d22rnwq/Yi2Diep3XNlDoYZ3vg8iUEM9Y5mEAiG7K6Hqcxu0INF+8xm6TG1+gPHMT2TIPALuzWiw yQj+jnMJndBjh8ZSUkYaNz3b5eELL4Sg7bpHObdkTntLtN4VHKMevA276zRUVB9CGoPBM7xRiVtU 28zIULKZxZBenYGjPB7IHhwGMl99XCDmytGoT+nQdBgMCCOHEz01LuFtYfDIIn5SFIxJkhERU4Io Dbk7ugGyaFOhgFPS+JsHrdKSTuxT+Li3uTdscpKoqUjUEmIRnrSSb1LDSjJlZExENmKZXlMmKqrR zD74LBzQDElBtslNZdikm+AMpzjHSc5ymvOc6ExnQbqVSnW6853wjKc850nPetrTDnIp5D33CY0g AAAh+QQFBgAgACwdAAsAmgErAAAG/8BLZ0gcXkDIpHLJRBKbUKSwc4xao5rhdYvMdrjg5LSafIbP TC96LR5q2Osxl0gGFe9U+NWtt6r7Shoeg4SDb32EaIIeh4BKHYOOdpGSgYZLiZV7lJpYg1+dUIuN VoSkhaiMoUifq5MemouppGyZYaOhkLCOuqu4Srauj5zCSYugxV2XVw+mwKnOq62rvZWyqLRrwVy/ mtWA37HLSdvF4cnHycbjURvRrNDsmtO5xICyoeVX3ZXncP6O+IHQ5wqgq3TqQAhkgu2ZqoQDPSDr ZJANvk4EPT2EuKainoUcQ1qSCBGkQ3bvRNbbJeniPHtbTKqE4hGOzJkJEaq7GTFlSv+ckmqecVkp oyh5QGnCDIg0aU566JoGknVKqtOOS20arZVVY7arw1iK2wj2KUmzXxmitFoWjNBbGTXIPdOsaxMh n9LenWtM7gMpfqfWiRlxw2C6S/BKJCWXMd9bgaNciNxFw2GmZ/U8aNxXw18QijvoJbeWLJjGn7ls tpxktWc/rEG4Nlb4MrM0GeM10YWKCe/Mr7b1HumwDLFrhDZcQTXx90TjycMGmw5tNyHem8QiH6R8 TiHcs6xfV8vS1m+xUHyyTQ/N3XdMwKE912mLuXTg68YrzF19iftU5AVzXhL/FZJaT6QhE852g9gG j34PlrPdfWJRB6B/ulmxYDwOQlf/SHfK9Affe8U96KFdD1ZlGhfxXPjMRPGAuF9m9RUC43AjZkJU jkMIl6EU1/FWxRuRgFKXRLzJSMhf7jWy4SfYaXjdIRcESUgdVmoXkR0lRtijPS1mNxKSW8mWpQep MYhelVBe2aUtRMLyXBPqrbhFIl+2CWZ8RSKYHzLmTQmknh7UoUuem/HHUjhH/nUkfIcsMlJVgBJT TThPVoqeb3tGSgyboOiSpjwWQjeio1tlStqmah2iKmgwLSPpm8etl6JDo7G3KCezJkirdvQI2GmI Sjw642SKQqfiqmF5mlk39NWqirDA0ogiprLSg9CTtJTqRGnMSlmtpvsso0sj0Yp1/26IN5Ynba63 rrqBF/Ca+C1L/EBV47jh3tssuyWOsmOX6/ZLrbPIQBvsnl9A9aqfUWD7kE7bvjsiweDaG7G05Pph 7jjp/jtju/3OWG+dvR2oq6khUvrrSB37qyzA4QrsYr8Fa3wwzSb/WfKRi8j4cKqWZvvsNNxejHPG ECvFr8ZHPZRzyDOP/HJ+J5eWypzksdyzrwZzXLLECAdsyIRKv7Is1AVTDPLCm37SYFgwlyyeyG6f lXSXEOcMMdFPN93EL1PDjbe+nATDU7wmyhVlKZx8ky+f7gZO7eGUt4w2xmTti3nCb1uLXoFo0u0z 1HdXrVNPf032Wstp98004HWjDv+eq6HHrDbPf1t8Jzt8rJproPiuRTLUVMt8b9mrDvmGLGZwvnbT bWubu91swjT0tUVPjLidX5dM/PS0ny744E5ez7bRxze9eE/DQ0Vn5LwafzXPl6vusPwDL9154t1j XviSh4QjeUBGr6jd+ZYgMTs0DDj/URns+Da++zlNgWUqVkTQZTj9ZQ55toLfcuTXNeVNrn2K66Dy EqgFqGSvDv3TmN8850HQbYSAzWOg2GynQ3XF4zkQmlTsKhg2VpkOfyhSQvZuqMLdWa2IQvwd+FbF Nc5h7UUWJKDEtlbCEBlRdv+r3OeuiMRNRbCHGOSeD+WzhP4JxFtO1Jka0/hFDBX/goOiGyMUyTjC KT6oiv7jY0RQuEPqdY+LsYshGMkXQJ4pLI9tXBIazVe+eyGwCf+53RDpF0a7ccpySYyQ+gzpvQ+6 L4Q/IQ8gZVi//xESlGsMyyWZkD1nfZGIclyjAB+pu3sVapJlFFPVpBhJ08BxhgCsYwIpmcQ7Fg6S y+MdDSfYRxU1Iojz21XxXJnFJpINDDpKVjT3OM684bGXPTkgMJ+4wCPG8XeMIRUxcNk7ZW5Pmf85 wjN1Vz1TptCPwsMVFfvotRN2E5rLHCeLSKJIek7TieZkZtzKcU9hlpOEg6pWt+bJSUbas5BbicY+ x8a+g2YtjNfEqBWpOciD8rOR/+xcwqMa2lEL9tOG57QbctaJw0/qMZtRFF9NyXlBiRJUoVosKVHf V6eU4qeLkrPfUr0J09W1iqba9OhPeWm3XtijouLaKtJCt9EKDTWXFmVnSM+a1FK+MqiQQ+lA41pQ qaLVqF6D6PfYhdVh1lOsTEQogr4K0jnW8HTPLKv0LJi6YNIVqVR1q0kXKtc/HjWhBp0qQr8Z03Au RpzvfOhN+YjDVuTPsRvTpSPHGljF+k+rYcVrFHDZVgH+VZCzLY1TiWlCu94WtQnV6weP0VeF/hYe zoJrE3FxWrUaljTJFQNr4do0XDbKTM91rjJp28QNEmuyUiRFzlKZtqhyU7MvRf+P0Yrl2RmhJzUO TWbtkHm81V1qHGD1CmIz5iMgcjSrxXngR2GZnTcALT+7WF3F5LojlY4onpTI5GXN6zKiHperoaVE L9S0W+Omk0TYTcWBQAwNLFFCJ/nNLSUMaKAcxQqOi1QC6Sqp3XJBA4/haU08DnQeHzWTHSzOIPEE uVfUhekkBdyxjKGRqBu/dkw48uJPiIJIsIGRjlt43HaycTMvUvCsIY5yY2tshSC/rcfguWOAQOze 8K45lENmaZEFp6YeblPN7B0Oh58snfNd4yvuUaKNitkdYwW3p2P+813wbMcvA7iNc6ExohODp7eB oEBRawo+yhHoamZzbrzFrG9hH+rL8z3JKtGRDRQkGAZWt+XVOMlgSFwNa1rD+ta4zrWuwRnKXfv6 18AOtrBdkQlDD/vYyE62speNxgcy+9nQjra0r7JEN0372tjOtrb1QLpZbvvb4A73tV0XG3Gbe9dB AAAh+QQFBgAgACwkAAsAkwEoAAAG/0CQcEgsGo8gCnLJbDY3QqXzGZ1ar9gsEZrUeofcr1grHWel YXORW1a73/C4fE6v2+/4vH7P7/v/gIGCg4SFhoeIiYqLjI2Oj5CRkpN6bZSAlpeaWJmbnp+goaKj pKWmp6ipqqusrVedfLBuUrJEHmO1ZH60XrW8roe3arlGxEeZxh1MXMpdu8XPkM1URciqxnfWa2LC Wd1D36DhIOFpdOOm4+ij63zqTtNT2Fcbwu1Y5lbx1Nxg9mLz3OyLM1BNPSH38iTEdiuhlXyJmnFh JkqiEIqBAuKB2OSbRRAYS3F8peZjSFQTgamUNHKly5cwCTmMSbOmzZs4yeXcuWegRs6eQIOiQiO0 iqiZRZMqXerlX1GkTPc4dQUVU9SriKpi3co1UkFNLa3epKC1a6xlZr98dRU2rdujb+PWWfuprNy7 pH4eMqcXr99LH8X9HUw4D93CiBM36avY5eG4Xx87aXsnsl/LgShvwsxE8k7NRqHhadjYK1pBdq1o Bd3nHSvW2y6l3poPNpPZBo3YBmqpdiDPhHaD1A0vTxrhsYNvMVSG8RvgSI4fCQNdS/VC0KUXw23H +TFK3s2E//Ir27A+40urX8++vfv3wEjrhL8yCAAh+QQFVAAgACwdAAsAmgErAAAG/0CQZ0gcgo7I pHKJJDKfTQ90ShVKq1gjdhtdOrlgpjZMPo7L4fP0Gy0W0VU1XHydIzdPvL2s1++bf2aBS32DZXWG UHqIiUmFXH5UkYmMgZV2k3eNWI+Dl2ife52bcaR5gqaaIJlTrEyuf6FzsnynqbawoJ6ko7divo6o t71MHapVuXa0uobJwMGrlLubxM/CwIvYR87QStzT0s3WnNvjabzl5uqqy3/Viq/r4YPfz+/ySu21 0fjm2b734hHqZylRPW38CD7RRyagQoPXTDnc4IfVwYe/xGHkd3EcwzAON7qLiC4huYEiD0GURBHY FQ8HW96RuW0SzS1+jBl6GYliz/+bnIC+stnx5Mc8NH0m4QlJIBilT4kmuwk1oU5R4NYs3brlwjlv xcAgGpvxyFUhm+roq8TqrFZ4W8h+bejUjtuFVBj9KwWo79uiYZU9uavEaxINwtjuOboEMck9hPl2 I1PpLGCV+8BaW2b5cVkshlHGZUwnr5c6kUHcVWxmrd+ltOTk4yIbDmsrhy5drD0XWV3KY2V9+rTX y+suGc/UM3zFsUY/jq+E5upV+nF+1rPMIhkSCfMjzm2jzF4lPFoQzotLTIfzN+bGxp96ni+fPW37 2jkK66S+d7qjlVzxSB3/sNaRgIuNB9J/7PXH1YALmuTbEsYMAZhe+J3XlIafoQL/IS4HZmiafhry R99317AGYHwfYsediCNedp2DrTCYEI0e2rhhTKRgKCGHRr31oI4oCcXXbunsZSKQcJ2lon/ntVhg kZTBKJaC9f1TEX0IuphlfSNeCU0mR+HIZJc49hHijzHquKRr8UGz4mwkEoiKgVWyCaWZAmnJzl9E nsTjUKRFREyZXLIY6JhrIlmnKlsyqURqTPIZZ18tDjVmnjK+KGmNXkYqXJL09Qkmbu6FSSqdG45K Z6aE4OEHG1B0ed+jq3rJjJxQovmYK929mqBmjNFkq5m+fgrXoJLFpRmZEbo6pK7n+Simo1I2WOqk rP4pJleockgpidcOy+tIi05r/+mzpwrp7KbdBllrnGO00+hX2d64rbvp8vvpcKbia663WPWbI7WC tjvvt7leJ0mi8Tos2q3Yuqmtskik9iTDnllrHrkUD2wwFW6JCijCEzKran6QXiovXhHve2+5ur65 HbG9mlXFVdOB/G6nle57EsrqCt3yhs2y3LDRIweoM10C06zkxcuEsvGt06IRbNbi4XyzyQvDmrLC P855NLjtYey0nkqYN3PINVMNhltXv8v10D7nB3TdWNAtd9gjB5y2ZmgrnTeiait65ds/W6wvxiD0 HPG6hUcZOLtR33wu1MdCLPbDbKcKLceHRutvsvZyGvXUjxfqqdmYXh7a1rEL5v9112DD/DmoKh8j 8cJn/26LtLWvy7jejucOMxLh8Z205XFXe/Hx7xHMjPKKUx78hIQL32Hp9RF/cJpmUN9m9NhD8XHQ kLsMPesvTa+67Ztfb332TOcNavf5+zh6q6dbVSgWYb6TsS59SUCR+7RHEtR5q3Oh053IiEYzCo4v f7SziMjAB0DgFW8+BJwf1DLRiejgrXIMVNY94oee7SGPfvcTofGsBDqVDdA/HEyb+OC1vwLChYX/ wxIqqsMe59XwgTT0YOM65K8U2upi1psSm2Tlr/0lxCvj4lcOwyA539noiXTSALAAlxJWGbGM53va njBoiwhyjB49wlzl+hGZMUqR0ItwyITkENGzPQoRa2CQnNvsB8PLDQ4PrkvgCRfJhC6ubItZKdjE hAWu9XFhXJ+4iwJjaLjMJCGLGSGhkZbHyQrq4SyWDAQoJ7MTOXqPlEoswyrRSMta2vKWuMylLnfJ y1768pfADKYwh0nMYhrzmI1QCzKXycxmOvOZ0IymNKdJMm5R85rYzGYZq6LNbq4jCAAh+QQFBgAg ACwdAAsAmgErAAAG/0BQZ0gcgo7IpHKJJDKfzQ50ShVKq1gjdhtdOrlgpjZMPo7L4fP0Gy0W0VU1 XHydIzVPvL2s1++bf2aBS32DZXWGUHqIiUmFXH5UkYmMgZV2k3eNWI+Dl2ife52bcaR5gqaaIJlT rEyuf6FzsnynqbawoJ6ko7divo6ot71MG6pVuXa0uobJwMGrlLubxM/CwIvYR87QStzT0s3WnNvj abzl5uqqy3/Viq/r4YPfz+/ySu210fjm2b734hHqZylRPW38CD7RRyagQoPXTDnU4IfVwYe/xGHk d3EcwzAON7qLiC4huYEiD0GURBHYlQ4HW96RuW0SzS1+jBl6GYliz/+bnIC+stnx5Mc8NH0m4QlJ IBilT4kmuwk1oU5R4NYs3bqFwjlvxcAgGpvxyFUhm+roq8TqrFZ4W8h+bejUjtuFVBj9KwWo79ui YZU9uavEa5ILwtjuOboEMck9hPl2I1PpLGCV+8BaW2b5cVkshlHGZUwnr5c6kUHcVWxmrd+ltOTk 4yIbDmsrhy5drD0XWV3KY2V9+rTXy+suGc/UM3zFsUY/jq+E5upV+nF+1rPMIhkSCfMjzm2jzF4l PFoQzotLTIfzN+bGxp96ni+fPW372jkK66S+d7qjlVzxSB3/sNaRgIuNB9J/7PXH1YALmuTbEsYM AZhe+J3XlIafoQL/IS4HZmiafhryR99317AGYHwfYsediCNedp2DrTCYEI0e2rhhTKRgKCGHRr31 oI4oCcXXbunsZSKQcJ2lon/ntVhgkZTBKJaC9f1TEX0IuphlfSNeCU0mR+HIZJc49hHijzHquKRr 8UGz4mwkEoiKgVWyCaWZAmnJzl9EnsTjUKRFREyZXLIY6JhrIlmnKlsyqURqTPIZZ18tDjVmnjK+ KGmNXkYqXJL09Qkmbu6FSSqdG45KZ6aE4OEHG1B0ed+jq3rJjJxQovmYK929mqBmjNFkq5m+fgrX oJLFpRmZEbo6pK7n+Simo1I2WOqkrP4pJleockgpidcOy+tIi05r/+mzpwrp7KbdBllrnGO00+hX 2d64rbvp8vvpcKbia663WPWbI7WCtjvvt7leJ0mi8Tos2q3Yuqmtskik9iTDnllrHrkUD2wwFW6J CijCEzKran6QXiovXhHve2+5ur65HbG9mlXFVdOB/G6nle57EsrqCt3yhs2y3LDRIweoM10C06zk xcuEsvGt06IRbNbi4XyzyQvDmrLCP855NLjtYey0nkqYN3PINVMNhltXv8v10D7nB3TdWNAtd9gj B5y2ZmgrnTeiait65ds/W6wvxiD0HPG6hUcZOLtR33wu1MdCLPbDbKcKLceHRutvsvZyGvXUjxfq qdmYXh7a1rEL5v9112DD/DmoKh8j8cJn/26LtLWvy7jejucOMxLh8Z205XFXe/Hx7xHMjPKKUx78 hIQL32Hp9RF/cJpmUN9m9NhD8XHQkLsMPesvTa+67Ztfb332TOcNavf5+zh6q6dbVSgWYb6TsS59 SUCR+7RHEtR5q3Oh053IiEYzCo4vf7SziMjAB0DgFW8+BJwf1DLRiejgrXIMVNY94oee7SGPfvcT ofGsBDqVDdA/HEyb+OC1vwLChYX/wxIqqsMe54HuXLbi2Avd58HLCasbNrnGlNgkK3/tLyFeGRe/ chgGyfnORkmk0wWABbiUsMqIZjzf0/aUP7hEUImBANrylta+cUSUhowS/CIcMiE5RPSsj0LEGhgk 5zb7wdCJQ8OD6xJ4wkYywYsr42JWCjaxJ/plfVwY1yfuosAYGi4zSdBiRkhopDkisoz8OAsmAyHK yewEc5X7ZIfK0Mo02vKWuMylLnfJy1768pfADKYwh0nMYhrzmMhMZiPUosxmOvOZ0IymNKdJzWqS jFvWzKY2t2nGqnDzm+sIAgAh+QQFBgAgACwkAAsAkwEoAAAG/0CQcEgsGo+gB3LJbDY1QqXzGZ1a r9gsEZrUeofcr1grHWelYXORW1a73/C4fE6v2+/4vH7P7/v/gIGCg4SFhoeIiYqLjI2Oj5CRkpN6 bZSAlpeaWJmbnp+goaKjpKWmp6ipqqusrVedfLBuUrJEHWO1ZH60XrW8roe3arlGxEeZxhtMXMpd u8XPkM1URciqxnfWa2LCWd1D36DhIOFpdOOm4+ij63zqTtNT2Fcawu1Y5lbx1Nxg9mLz3OyLM1BN PSH38iTEdiuhlXyJmnFhJkqiEIqBAuKB2OSbRRAYS3F8peZjSFQTgamUNHKly5cwCTmMSbOmzZs4 yeXcuWegRs6eQIOiQiO0iqiZRZMqXerlX1GkTPc4dQUVU9SriKpi3co1UkFNLa3efKC1a6xlZr98 dRU2rdujb+PWWfuprNy7pH4eMqcXr99LH8X9HUw4D93CiBM36avY5eG4Xx87aXsnsl/LgShvwsxE 8k7NRqHhadjYK1pBdq1oBd3nHSvW2y6l3poPNpPZBo3YBmqpdiDPhHaD1A0vTxrhsYNvMVSG8Rvg SI4fCQNdS/VC0KUXw23H+TFK3s2E//Ir27A+40urX8++vfv3wEjrhL8yCAAh+QQFBgAgACwdAAsA mgErAAAG/0DKZkgcUkDIpHLJRBKbUKRwc4xao5fhdYvMbrjg5LSafIbPTC96LR5e2Osxl0gGFe9U +NWtt6r7Shcdg4SDb32EaIIdh4BKG4OOdpGSgYZLiZV7lJpYg1+dUIuNVoSkhaiMoUifq5Mdmoup pGyZYaOhkLCOuqu4Srauj5zCSYugxV2XVwqmwKnOq62rvZWyqLRrwVy/mtWA37HLSdvF4cnHycbj URrRrNDsmtO5xICyoeVX3ZXncP6O+IHQ5wqgq3TqQAhkgu2ZqoQDOyDrZJANvk4EPT2EuKainoUc Q1qSCBGkQ3bvRNbbJeniPHtbTKqE4hGOzJkJEaq7GTFlSv+ckmqecVkpoyh5QGnCDIg0aU566JoG knVKqtOOS20arZVVY7arw1iK2wj2KUmzXxmitFoWjNBbGS/IPdOsaxMhn9LenWtMrgIpfqfWiUlI w2C6S/BKJCWXMd9bgaNQiNzlwmGmZ/UoaNz3wl8QijfoJbeWLJjGn7lstpxktWc/rEG4XjfI8JrU tMVigtZEFyomvjO/2vZ7pMMyxK4VvoJqYvCJyJdHD0adN3BCvjeJVV7bbaE00L4+V8vSVnDdTXyy hRLP3ffdE6FB12mreViouc8S3Z2Kifv+/AVzXhL/FYJbfZmFw90gl5GG3UkwcXcfMdUBqESB70Wh YDwNTtj/XX4ZQogegiwNyFxpo7EXT3HPxAeNBiMhQyJUFoqoTFeFDEFcPEpQgJ1vVVwDSl0S+Qaj g3+518iGn2RnhW+iSfEjIXVMuV2OxzlY5I7WaZiclegxQaSOg6S2oG4+Nklllj3lB116KGoD5pb2 0IhdiPRxAuUhadLZQR26kNnBZhmZRwyRfxG52yGLjFSVjMRUEw6TkIYZ1qI39jiNLmbKU2F0/CW6 FaUObrEMqaDBtEyjbAbDEzxk/cSFoSyxSpqL5X2ZmYB1PmSrbJksMlmhepZWanSM0tNNnleqwmuz lWoXVrKZIcQkLZ86YSys0tIWrR+njsPstDfieuyNKcJa/1UHGniRLrfa1rqWufCWe+4r5Cpk5y6j 7MemLuveC7C96Hp7b0RfQIVqm09Guqqym+qKLYXFxsrJqLp+61W8jYyLLMH1urqeuiISgpuKJXLC z773ehxvvjox3G+N9Q587rPUIrMsPcEQuciRLxtcr1Ji2ayTtRLz9++2DHsJ7cHgPWSzvrs67CvL Q7/a07qpvEkeqAXf2mrGAludc5Yzs3ju1E3jDPLOVY8oEYOXCt000TBDfNa1Sq/NNMZPD93EL1O7 /MrZNydtqrFyOVlKxbQ9Onbgd0/6sHDBGiJh34dPnne14vJsD4a4LQz457j+NdlrYd9La8CCX0f5 VoSHHv836p5HPis7fDiYIq26i5347Fbj7mCQb8hixtIW51r05TrbrrGU5ZhuF74fU41rWgJl2/nw 3YK8lUJLSl/21ZhfrPiJppHnNfPBw0Pv3YZbjr5z+Pnrd/PnI051x6LTDZHYtQTrWQps8fLTRP5z stYN7XW5c1qMoGYFn9nNbdqL4P921z7+vG9/8UOYButnNQVqim65iQIEwZe9o5kvdj0ZjAHDNxz7 OMRr3aNYyvgHw7qJ73onfGHloDfCkW2NfR+smcrmVcTbIbCGWOIc1Q64wpCZ7W1CLAcDC0i2Hj7x PA8aSZhyKJYqtu16M+QChgDoRI6B7IzNepesPMg+BK7/LH3Om+DQ7Ne1r6UQZdmz4vPuFz/D3WhQ XCTeAYMWL6C1oxxkZB7s7tabLlJShQ354SD9B0dHcfB3+PEj9jYoPEHqcYiDdCQU+kQtKlZskhh0 4UYMORwZWvJ0gayjJ9nUNLaRiIa0JA8jChdA45kyhJhsXiPCmEw7MpGFmvTh9xbHL2LtEJZXzGDr aFkIVaZRgrk8EWM8pcNc/rJhirzCf45AzDZ+L2bndGAy17XMUHLuG3ecn8jcab93yW+KzXQjNN+p NzZOD1bo+SbeWmjPVK3vga/UYCXT+TipZTGb8FRfHD/pkHoKB047DCHW6FfMLxKxCYrSnxJ5iEr/ we2g/8pJ5ClxKdCYSTGS+8PmIkepzUve86KbfGM8Sck+ejooib1cosX0ecviMfSji1JpUlkay4Je 0B4memIwpWk0vYGinRMrY0QHOtGZXq+KJCTkQLWmno0wE5CMzGcTp9dPoVLiGFI141C7CrpZlrRU WG3qTuvaU6T51TTe86VGgflXuE4zrZwcKlvjBCukAs+BI90nXTGKNbxa05yLfWr0DnvQVjzLrIPl bF+/aruwSlKiskOtLh/bWL4ydaPUNKoXQYhZPLastqqll2dxNNZjkoZau/xn1i5x2qumVjeXOyFr ceu64iIKWGgU7GzbWVr0cW6fcuTdOOYIv97eVrZPjP8IcluTOVjsJzV6DS3BFCtchVFiagod3AsV u4sdQSexpZkbTXsKuDdY8JBvNKxR99NQ/oyTEv+hpjOXKlHJ7ndbvTiTR8PJI/ZC40AVKkSV7kqP /IJ0FwM0UIBU5b2pkgJDA94qiN6hYSWk2GQe4tJOj+hhmjkWn880LkLV1hMUxwM3MB5UjVf6YJpx hxZE6eMzyhtN7cgrkzZaQpTLKVAk3Di7FI3Cl/0KxqgVIhsd/mNF0exjkE5YcmQ9UyKvfOYl3PiQ WDbjcC55ja+4J4gf/ZmXL1tlxs6xTx38c3WvmYa5xLixq7QSAEFQoKPMER9aBOIcUdEhKsuVrHuu nq5ZrCKdBnpZM21JdVvGJxJTq1o2r461rGdNazntuNa4zrWud83rolBCUb0OtrCHTexiD8dxxk62 spfN7JAgek3Njra0p03tM2BIldXOtra3vezVxYbb4JZ1EAAAIfkEBQYAIAAsHgALAJkBKgAABv9A jXAoBBmPyKTyOFw6mZqndAoqUq/Wq9aYhUa34GU3TB6TwWZnE0lsf8/TNFwpn9unj7uea8zfv357 goKAg1iGiEiBiU5+b4aFjIiLkocglGeRlZtSmpx8n3qYnI6MnqFwo6hsfXqnq5yvm4+wTxdLqpWl ibK1V7mwvWitvp/CpsVkwIy7iMfJuNBJD8taz4PU1djakNJb3IbUktfexOWD5OfqcetS4O1P6d7v 8Grm9fjs+Yr7mff79PqBCihQGq18BPfJ25YrG79pDpN8OXhJXCMwiyxS2WDkFkSNuEZNxAjyo52M 9CLaK/kx4cgzCZWoVPmNpTaOIDwqoimTIE7/ED+f4ARHEZSRoKzsXVISVKelLY+cFp3yEymdI8Be NfW3xGqYhkbnxDwSdMOFqtOM+vF6dWknaEidPjzKlIkTuUKNUGg7ti3QulP2hoUT92K8f3AO4o2G xGpQsFVEfXqs9q4YxBLJAn67ZcNUtiIp4vQsBufijnzV4JxahS0X1lW+lD0Km2xtmZxVaVithfQw MRQh/wV6G7ce37SDV6Y9+rJbNq5jU9mtRzAeu86dWE8SPTVVfYGKHnyJaPuTrJi5B9a+Malf4ZIT UbLe7J0sTeLDDX5uPHL23Fxhkg5+SiW1kHEHweddUi4dxh92752HzRG31DFdem69oaB/IpmT/x+G 3+wn3IfgddLhgxxa42GB2B2Yln9z9eecgCByNuN/7m0olhPdKQWZhhJmhmKK+y33i2EJBgmjkCVe IRViA66Io38uPpSkYT4uGMZU9xWoYyoO/vYjVkpid2J4XobI2JWMLekegF0V+UqUz5GopTIilnkn kWU4eGKEWMZH5RzC1KcnnwxCyCQ4qjRDJpZ2+mmZpEJyQ2B2fSEp44tZVpoYpUwueqgdFooZJJCB DnRjkW4+FF4djmKI5pSrfpeop5bM6pcksQ4J4pw1PtqrmbTC+CUvW8pq5KaIEssqRcUhyOyjrbKK 6xRyAevrgrIJwRuF8uWZ6rXOkuFal5iOiv+MqZoqS2653VJX7Y6tjsgiqJvtSaeuob55krht1lou GNGhC2jAsyS7raHjosuvv83hWa+SkXa6xGnNZmxxxUeYB+bE494qshYYD6xojuoiy+6a1DLr8Mkn P3wkyG1yvGeuN9f6xQXZsJSTfjRPa7LGeV04JInHOqPwmO6ODG9HPWf6Ipv92fyuiijuCzNnPVLR a9LagtO1xkinrPTK0jY9NJ/RgkAfRgBXfa/FUmQLZbCqWsujIF+bHTbJ/Tr9bMucxrL0qYTHmPe1 bQ+qJtWcWi14nIJrPbgUYyNe+OZXp4MUl5iVHfK6ULmLKsJkS7lrfJDPJfnaRtO4LeNza8b/utCz /w33vKmnO7rKpS+8LOcvX16sO3FHXnvOtm+ne+xbt0rev0FzXjneVuIb/em4nx0808JfzXaax6et uOvLi4+EYI883+S84+n9OO7oZY39o6AfTT7q4xzebviTu9TBAqe581HrdYsrlvvgBL+2NO5/iYvg 0A40rARuT4KzM1eYsAa+DRWvgemJVt8glT635a1Hs5KdpVQXuJd4bHdtq58Kv2Itg4nqd1zZQ6GG d74PIlBDPWOZhAIhuyuh6nMbtCDRfvMZukxtfoDxzE9kyDwC7s1osMkI/o5zCZ3QY4fGUlJGGjc9 2+XhCy+EoO26Rzm3ZE57S7TeFRyjHrwNu+s0VFQfQhqDwTO8UYlbVNvMyFCymcWQXp2BozweyB4c BjJffVwg5srRqE/p0HQYDAgjhxM9NS7hbWHwyCJ+UhSMSZIREVOCKA25O7oBsmhTeYBT0vibB63S kk7sU/i4t7k3bHKSqKlI1BJiEZ60km9Sw0oyZWRMRDZimV5TJiqq0cw++Cwc0AxJQbbJTWXYpJvg DKc4x0nOcprznOhMZ0G6lUp1uvOd8IynPOdJz3ra0w5yKeQ99wmNIAAAIfkEBQYAIAAsHQALAJoB KwAABv9A0GVIHIKOyKRyiSQyn80LdEqlGKlYkFWa7UaXTq94uR2bk0PK+XzFhqPF4tp9Uc+h5XuS sun7+3ZzfmN8G4F6TX2IQoqLe4BKg45UF42TeH1cl0yFh1B+h3+ihptHmaWMG5OFo55mkl6dm5Wq iLSlskmwqGiWvEiFmr9akFQFoLqjyKWnpbeOrKKuY7tZuZPPetmrxUjVv9vDwcPA3VPLpsrmk82z vnqsm99V67bva+GL1+m15Kn+R8b528dEWjJSANtdyjcn3qV5UwgC9MIQXr2JGB9tEPZLYqQ/oS5m XFTxjEN29+ghHNmlZEORLAEKJOfxoDl0MR25JARRUMr/iDBz9urHbaVQjDPFBdXCKqTRo3d2ijnp qOeTmlCPSDWDNSsuhR2X8nM6zauYrV2oKqHAVsyxn1Bo1Zl6iC2FAsDu7imLRwPcLniVyK3bNi/f q2wD49GbF1XSMwXsGlY8GAtOnGkTe4l8iDNjxEg8A/NL1C2ZnoMgklZ0b/UGDUN30VL0QKMmWNui WeWn0DVsMH8EizpIXLWf2ZR86f6rxDXH5U+P+F4CC/dwKpfFUlcVnPd2Yaz9/C630ZslUcKmnxYf ELWy8eZHNR81frYvZYof3H+diCj00tsdh4RrfcBHzHVaIQjCLuoYuKAyyfmnThb2vfPfEgTyRxw/ /e32/6BRmGWhDn0fgQehbfHF106GBuqH3oEApnjBagEq+OEQsFBAmgZcvPWaFO/4EVg3uYkHZHlx PahBIMchdxCOGmqxo4lEDTJjNSNGqNGPD3K0hI9X9qHYfxw1ieV5luhYoJcBkvXKmjRCWZpCRtJI 3m2WHLlkfHLOx6WYah1UGwikJeEjXj4OZcdM+xR4hIt+1kbaoP+Q9xukWva3KJ1I0jLmOgz2MWih ByG6W5EaYoodQqS2F6WjmrpKZYrkHRafm9RY0mqjSHLoq6y0JkgULZv2muiBMH6S501oDlsMo93M tIsssinXzqm+EAvstqh6Emo/2gaLrYS97pZLuAfi6f8sQklVZ210BTGryha2BpsNr7P+mm6wlQpb bL6dBGqvvPyGC+1K0vriop5DoagvE9sY3I5A3X5U5bIgNpvpth+qZAe6Ca/774Yd1yqivKJooJiy 4KbJbL4lc1ytyByXHLB8FscqbrbPThzttb74mBSq6m6cysjcvuvtfi1n3M+4Dsd8VTEgA03zvjuT W++HTo3CZs7CmmwezNNa3bDO7TZys40xoxvzzEgfGEjIfoZDNL8Q88yuzxpWTHLbBD8MHLlFA4VQ 1eXqHffbSp/sdB1WeGhdP/iSXHbi6ypasyRrd0ey2+5effDcZlss5tkyMxdxz71+GJhmri59cdNO 4T3/eNTmUv0z5ppj/evlW+OUxkG2Ti52OmS/W3jYaHNKuRqsvDGw0wWzrsk1dJtu4N2CCye682UR 9K3Ov6uuvO1kBIL48kdvrvHx5ywlYPxNw+88v9kz72/NpD3nHu2WUxzHsFe60HiuP7gz37p4FKYy nW49svtc4KSWN8KhDwoFIA3peNe81oVOI8GTH1gChMDYJSN5FtTX6n7UQLCRJ0a/At379uc7AnIw CXZCne+g1qEXPYkToGIa+RgHwxKmrohPQEf+2uc7IoLQccUboQvv9bIAplBqK/San9byvyF+sIPX 2x374rOyfu1QgbHx4QuB+JTx0bB8SDTjElelxAIy/zFtT2ucZUTYunjVz4Rjs2ICM9fDP3hpfslK IsZqp0LrHW+OMCoj9yh4OyPSkVKA5NfkGElJ7w0yCxnaIPsk5sEZyg2KdPza9OxXyjxecWY6pF+x irhJQYLxkXaUzjcmycM3TiEf4hOiL78Yl/N1r00avFP19tZK/GknOytBpCL/eMpAZu2TlnQb/VxF y0XakoajU6bgDqi/M8ZxhVsjlDmCOTsvmrKC2NwmE83ZOzw6E15tIh6f6GjEyl1TnFgUIIVOIbAY ThBuAxQj3lwEK0tC0pO3nOYT/1bLfxbzlcx50McU2khmonCidMTVjfipP3/CMZ5mJOXXElVQwFGv o/9xs+EYdQPRIxpNpfGjFDsl+NJO6vChPBXlMhdHzGqGVJ/8UKVBKVdFi9Izm458ArFaWtGTRtSo c9zRO3iJxqtSbHcRnB4ne/lUlpFviTh1alduhdSRyrNfJnUiQGF5VZtlgqredGpasZrL1LSOq+cU 6MG4gLiwLnWsXbXpW9c3VPe5EqSybKs0/djPplpVseXcq103glcA6jWqfL0hCBYWUIwG9nu9+irC gtjOYb6zkpiV6BvRClq5ZjKyyWCSFHnKyo/OVW/1vF+6OuvOx3rVshaCBF1jC8+6NsNvmswrCA41 XbICVay/Ra1vb8uyQ6ArRFN0Wca2W9aUgvZYwVD/i2KqalusyRBgvRHVPAHrMXHKMBklcqFLl8aj HErVmD6NldDWeCD4qNZNatmtxepCm2Py9rbCpaAfauOkTB74I2H7j249q8sTHcFHoigjLDI0J7U1 lL50rAWI/7AyFpEwuhzmDTlhW142tuKFBjEgfnA4If1OszMN2iM141rUD+FMRR9Wh4hHERl1bHiI F9oSZk7CUPYgwUWXMl523ZCjGyehyvegihvnWV0P/9e0xjByHTO0HpAoAczVaClb0zhhIVd2vN/k po0qvBxP4OVFGsYuj8MDoGiU5R6TFYiPBoViKrQKRvjkmiIpKl3DBLic1y1RMtvjHRvDK3rzyGiI ZirUBS0btUt5FtZGvvFoQz8hh2UMzRxibZZa58RDGaG1rae76177+tfAflMcg03sYhv72MhGiYpx nexmO/vZ0A42Lfrb0Ghb+9rYzvatj6ztbnv72+D2CbPDTe5ym9vakjm3uokdBAAh+QQFBgAgACwd AAsAmgErAAAG/8AHaEgcCovIpJKoWC6PR6d02pxamdescavteqvecDRMhnajYOWYrEyzr+43SEOv 0+XDeviOV/L7f31FgXmEgk6Gh34ailaJi4yDdpONkpWWipN6eJtdj5yRgKGNhp2XSZ+XqZWrRKZz mq+Zo6y0oJqito66ooetZKW/vrynwoK/FK+xssOnhaTGWcxT0VrViMRywdm1zoveqNywytdv5dLi nufY6UjrTnHa7V7vgvHg9eq75POH972z+l2ZJiUfOFjFBB5ciJBhw4J23Bl0SE0hRIsX92CkOFEi xY8QObbjB9Jbx3G1FJ5MyLKkS1cbNaKjRfCluZjhxP2DdOZhkf9/a9Q4eVBlJ5ELdCgEtXJPSDSj ZYYWJRPvztRTTkcSqomVzdKjSb/CkUSsDlI6F+KcRUtIwVoNackGSmY2HIUhCkxthWvn7sVAbu3E zanBL0y9gcyaVauHq09Ybw1PiRyOMpLAiyWGQuyYpMa3FyisHQxTIujKhw8DBl21bqGysS4goYur yFu0ckPRjihJdiHfz3LXETsu0G24hPdyFo67yG7eIZlrIK46qWZKSI4Df526+j7NwJZN2v54mWSf nbAP0Z68MPclddemOR7owabhYJEfln1W8ia6HpHFn3VSnAWcfXzg111z6zH43msD0pGGeLtoFuF5 i0RIUyySIRj/iYIPmmLgQMqFh9xor0244YkOomccgx6+NsaIZz2YU37g2QggTP5tCJyDNYIQZGm9 wUTeN0TsWIhhCGJCJFlQNjhKXn905qORFUppmhEOKglLj5vtNVOO9PwxZHkrHqZilE+C4CWBIU6H EnyJpWmjiwG2Sc6dYnYXnZ5XBtemjYiRaWWec/6JJpuCohnmhmOSheF3gCKa6J5+Noonmwl+Uiin fWoaaqLBtTjqoU4uOug2jJZ4J5KAilMnopiKWuWoGUl3JE+VpnrpqbjOCuprsnzqZ62qxgoenLYy SietkK5qy3LSPpqlshX5Wme0tlrrKzvXqZdro8Heyi2pyTpK/2RtrdqJrrDSOlsjHWsAK+u5e/14 LqHwxnkvtP/Gm+mmx+IKrqRqVjRKv+ryuXC52t5KLKvVDsywvbOJ2+zAsJJr51IU82toKxhnK7DD EXs76MF48Touwd1a/PC+F9N7Y8vtjowvzTMj4aF+ETvbMczoWkqqsf5e67FKO++ss9F03it1quWq vLSlDJ/Jcaauvvsw1j1fh2HJikKmpXMEhXy0u6hiq4XW20L79LdRU/pyzXO7batvWntYr6c1W000 2fnJCbbQ4YT7CpWw3SwyqAHrPcUDawEsN+RQu8zy5nhjTnXVGgtpKuBfe97ryUXTNnTcJlfHzDRq I/1r5Fdf8f+c5Z/nrenmdSuce8oyO6tc6OOAyTnbwB6+9etNK/3lZUmonjiZa+v+7Oc6HYf76UnT rXnvd5deMcrBS3JeHDFu/XjBTgfN8VpBEX79ykvQdWTsgavv/qtJVA532NybXeYcx6+pBbBryELW Y8aVtvyRb2OSK87Ymte63TlBawukVsz4pzwOJklB8nOg1yLFNZL1q2rle6AF62eu41mvcxEUzPQi OEOPDWV0BJRdeky4vSWcKYTi6x79vqdBF6JOgNjr4ALJ0oQGBhGJB6Rgbtwgv9U9MTsGKyICeZjE 8PVwcC30HgHXZkAbAk+FCmRYxj5EujOO8Iisyw8Gq1hDMO7/r4RP3CHtXMQNHQLQjOwbIPXIaDc7 mq52qNuiB/0oOBgikjvMSlfbAEnJDMaxYUWr4yU1B0Q3KpB3RQSfIQPZxUQib5EiTCDPhMcIxilx kqNMVwE9yUUa5qyUldSjIOW1rUndEoJCfKQkT5nJ9QXzTe4xJXk6tUr9tQmZTHLkLMdXzDtyxY+M guYhl/g9PhZSmrrEpU+0WbC7OJGW7ZOWvrAYplfWkpJU4puEvqVFWtAIlpuEFTn0tcw8hnGIYzSb m6wURBQ6LBLSMyU718WhErKTXRN7ReWkNIkx7HA7dLyO6wjBHtvU84nPwecfo6Yx8yiOo8t4aCEj 2iJO+vOF3imVy0ZpEVI2QlR2xYGO61wqwyIZ05vfJB5E8fjLwul0fsJUAn3ccZw4DJWl0zKhLWpK ooLyTHA5Lda2mHEbv8T0p6K7A/Me4SXKMc8w2HQmjmSqhhEpAZl/NAQYXFlBoErBrIWB20CdCJvC yMJLovygWahjTINmsg4JXatqloCZZNqECpWAymOhlxBuSPYUVwHHZaWwWXtM9rOgDW1oHSPa0pr2 tKhNrWp958HVuva1sI2tbFXBIqDN9ra4za1udfszEO32t8ANrnBf8hxfDve4yE2ucnvCheU697ZB AAAh+QQFBgAgACwdAAsAmgErAAAG/0AQZUgcgo7IpHKJJDKfTQp0ShVKq9hhAcuNLp3dMFMrLnvN ZmNWfSwU31c01B2XQ8l25OPC7/MfeX1lfHljfAqFFIeFSnsXgEmCjFWKF4iTU451mEuOkFR9nwp+ pI+cR6MXm5OVl4WOpZ9okmF/p62Ji5yeSrSnX7q/jXyrwrxVoUippbanqcW5lpOwpLJmvljHmLh5 3JjaR9jCR97jR5rmSeBQyajM7ZzPwuV2sKfiVOvRrnL0r81I8M0Llg5dunMAn1RTBi+dvF/+0Njj JBCKvkIK+PUjyGhdRo3mCmQ8qIcYSRAXI/kR1dChgi0QOcqZiKnik5QnKcnMgzOnT/+UJkn2BLHQ XcKfnCKaoTnJJpOhSJUonXk06k+DB4c+gMWyqtVuO5c6HUQoDNSvQsLaKYsWKdaCXpdgG9u2y1Qx TBttFTnyycdlTP4CU2UNhGC9rrYaVgISVeNOlQJ/nNNXalA9ijE/4PvY8MjCN2UpUMwXJpePpkuq Kg3lsN5PW2VVogC6F9twt7vE9qyxcWbNvJeMlrX7XGThk1u/VH2BHbE+FFKTYzb4clo/yojiu03r eMDm2EH5ieNmvPTruSv5Wv+c2Hn16jtfT9w+9xT1zYeBx1ceunRafVyCX35TwLNMbQWqMh560SXx kGH1qaLfFYDhBh0S/bnHxIJA2ff/XSmrvGMZKXEMqBIp/LCFlXcWFqUQh+hdaNtKTZBy4okkysWM fN5QEx4VAxKI0I4jwmjhhwLaKJ4pRjFZyzs5MiRhk0qqRiGAMAYZopJ5nUhEH6kFmRt06iUx25XE SDGmLrexqJ0qago5xmxellmndWfe+OGXfKQGJY/BwMInFmnaOSSIMw4xF1sB1ggnMgAdSBac8Cl6 24PL8FmHQRVaYR2Z2JwZWZcfOtqVNMukKORt2mCVXlkssuiqnIZI851Ktl3R41HsEVjJJwVgaesT u06pHTSqmWrld5twJ6ew9DmZoJOSitFdMAld1imYy0LYJkHOzjhkh7QiOR210Crb/2EcrQbVKW7e Cimru0558+uQ7AY1r7RvnpgkuoyqNV+37z7VzL34NmlmM2+lOySCJ55KDm1cXGsrONo6vK7CjrqC MFYVekKqhf9KTLK6WLVr7KJx1lEsmuUuPOzHlxm0rzW9liwlgY3eESi9HqpzMECc+kKzsf2e/DCh kb6DrJ4DdyhLxgEPW/S3MzNMdX4il6JRzwgfqfR1kKRM9GW+APaq1UDH3DHKNevLKq/O2hr2tgK/ zLFFQzt5tbxaI63xWQZC+bTYUWNsLN5sT/muvYHHEfIfPg6rdNhJZ052wktzrjlubuqNOLHBHJ3v lG7a16u6iPdMupCzun3ruVM7bv+0ilub2/mSEm+l3nninnuJNpgO3rbMHke+88OVf60L5hqbrhps aKvuBz+iFzxY8kyCTAsgquq4KlvQVw0o7NXLjhsk5cMsc7fx6i41007SMSPEmXNDfO5j/4083IIr y3BGQ6YG+Yt2yxub9HYXO/EhLWobi999Sqe8D9VmHTlDYKnGVqtoxcEpA9RgBB9Xwdb9jF8vQmGi lvS2+RlFcsazHda4VzY8WYdczrFb08wHwNPV7oO5WQatslcvClKKTlDTD87qprMNvul8HnRiF84m Q8A56VM83N208CejHLZwf4uLoftaeJ0i3BAbI3uiCBlHQ88pDohDFAcRg+YomSH/CkNdFBq/Mri5 vbmugyqBYxjUQ70qyuwT/FOjFnPIxRuK74s7hGEWR3i7rDFjE0g8VA6bKEFF9tFs0krfhjgyR/XF ymn6QSEGmbhGjQGSWVJcEhXHeK5AJlBzhIvLnlgovN0Vb5L+I6OYHviuNIJthzwzYg2NpTJBik8j pQSSEXmTEeCJY5Xj0yHAkmm57dmyk3MIUiFpeZ1vdtIXuVShl3iZuEje0nXB7GUt/7KcR2oyhZxk Yw+nBz85+rNx5HxlHyG1CWwecKD69JnljidNQoQtnp9MJDp1GbGKWuhwFhueO/14QnJCTp2pRIQx n4dM+S3QhZQM4o/qSLAiWhJ//yzlZxKPuU35CfRYe/PiQCF60oSidIsWfRNGyacLMEqSm1EE50dh CsuRatNknjxpM3PaIkx2lKre1OBbgrdIPt7NlVkFHVZHxL5Z5jRsEj0hUxsCjzyO0ldF3eg5r6pU ZXpOfAVwaj6FdUg3mhWcLZJTNCdoSfgNRo9LzCYnM/fHsEL0rZzkKUDS2ri1ZmuyjuSq/uTqU8m+ 9K46wiE+W1m1vkYQpY+dTUIGq9A2ntZma7Ln5S6LVMLq0ZmbFKFn4ddZilowqG6V7WYBdlT5eda1 3iuLJvRKWm6aFpTjpGoo1pZU7Y0IuXFDXWy5qsjy1Vaht42lcP9KQgIl97s/Zf8kcDMLteF2pbj9 Y6g8IxpG5RKDuQjla0yh29I1xcmK1XWpa3HKuYfSTbHNtalj5ZtC1nl2mfD1ZDplg1n15S+uxH0n XcuL3fpy7b4VoSlU/4g79PlNlLiK6oYFrBIIf9PAe2TlQBmbtxXTcbYnNmSLx6XhytKPwtlsJFwv xlkxnhVc3VvTh5sDC3oe1LuISFW3vurhux4nbKy9ydy0G0oum+ZBoxOxzPjUzev215TNgIdB3gLb Lj+CgMEAs3qXhYjGjpfIGebosABT5y2Hd8a4+FXlKrzYYbpCiNfTLHWgdpksByY8iP6jlorkCq8e GEWEDfCNA6tmEc2oSufymh3/5fOmxEZpWpDM81wX6mkqfQjUnGbyOxBJUmkNupul6ITr7ghLHCf1 c7XK5nZcdKhKyxhzMbLz/zhn3SLRCCFBOk+uHZho5pC6JW9aqU7bqWqfxlqwvcKHicjlIjHbsckO dI7zVOG8Wzo6MKmryGxqg61jHyWve1E2GR/7up1K49npbrCdBVbqtz5w2+6VUoQbW6Z/fvoJGXIQ PSsjhskkpy6OIXUYKI4JkUhc45AqcxL44pNLsOYgHqfCxZXAmYNU0yUYj7nMZ/5xBdP85jjPuc53 znNUj67nQA+60IdO9KQUir1FT7rSl870ni+66VCPutSnHhVYU/3qWM+61s3yB5ute33oQQAAIfkE BQYAIAAsHQAAAJoBPAAABv/AgnBILBqPBYVyyWw6n9CodKpAWq/YrHbL7Xq/4LB4TC6bz2Gqes1e o9/wuHxOr9vv6LZ+v8f7/4CBgoOEXnyHiFKFi4yNjo+QRImTlEqRl5iZmptZlZ6InKGio6R+n6d6 paqrrK1aqLBurrO0tZyxuFO2u7y9grnAT77DxMVnwchMxsvMpQoP0NHQVV9M0BR6DxQUD6jRbFfR cc/dReJ453fkD3jk1FjfRNLz5XHpb/dk2tv82+yGTPh1YyPQ27Y2VvbZ81eEnx+F6Bje2fcPi0Ai /TJykyMRDkQz+zRW5NKkIBuKBrGBQ/IRDcWG2x7GjLhxYscrF4do7DcSzU3/lzNB7qzZpaS/NihP 7UPIMihQokIc0pQJlc5LeDmjDq165ueZlvqkjjHKDelRpQeZGgErtKpYO2znXIXrFWbWAnfr1C0T N0zIMmQHrkmaTNGRvmPmNiug2OpenTwxPi6F+MtfMoHNli1seK3Tr5OHNZYbOuPIvK0qe7k8NuDZ wa9jTVNz+HPbnh4jhXxGl6u5kKdDj1LdhbWYzCdjK5UmS55tvsIT6+ZnCUz1JAmjZwWOpYkm4lyM /8ZtBLmaa9wEU/m2hP0zf9LSU3F+lC/6yELu5ctyrTu03+88RcFx+f1XRTrvpccYPRXxFI2D/0nC 4ILkTTNERfEUSJ489VB4/2FBbQ2IxFC1iURWbCGlpUSKKrX3GnUJpnefaVBAdleKFUb2j0aSiagV j575Q104TrEYHWP4fShSiRJRw5pYLDIWYBLlZKUAahdO2c1QUSZBzZA/JplfR2KZRl9dOI75XJgZ mTPUif24GOeKO5FFJ3zAPchljXglSeKZAv3T5Y89AqmkRlO66SOSdfK35KFt2pXRO7sRqqZDHV64 5U1YLjjiVm2+Ux+bN5IZlJmk2rakeIXeJ+mkcqZnEo5LBGqSEjDOeeVRM96nnnd5CrGrrAf16Oul UL3l4Ft9Nprdonl2aqxxRt407LGXfhlUmplqelen3dpI7E7YVTFqs9z0Q/9fg9sGKqytxSrpKqs2 KvnOsLWqmOBAhPV71m75jitYoHcOrK8TjK6rZkW7CtpRY8q2i02PNiZKn8KWWtGwmpRKNSzGrFXa LMgWY/vjhuFmrNCB9eFaVr0ZM8outEVKpJhUS9GrMkMB9ywnv6/5uxm+sQIXsGCEwRhFS1fN1fTD P0Xs482nxtsUzUQxG6TDRD1Zc00hl/m1oCVzZ+M8HH46dUwsvyyzqFVjPfPF8i5Mscw6j7yway0q vW/BPwfucosxAjy4NS8e7ATTNkMNtuM9SV03zM1arCTGej/LNYZiy33poZTLnF/Z3/5JpdqXt10P SpS/NZfrY9sNM0VGGgH/ZWxK+52U0Ej/S9001SJOeNKKN7HU5E433nXUToFJtY9gqt1x1msi7zj0 zSu/dtwkH2Z2qg+Td/v2DHPK/eSZJ2x9sjPRbijlQvet7+5B15+W0QHfmqDwBhP+xPGyS97jZISj mXHtZQKUT/R+sx3tpYxRDMnJsBTYvhS1zUcfi1nTSnatablqCM+Y0vjQ16fgYM9zGoyd6GYHn/ft bGhEi+HfZkhDgBlucH7bn+Bk+AQYBdB8IlqHnuBztrOx4yoxqlh5qgQf1VHpd7jpxku+57UBMZFX QAzdBotAjmYFx4Q9CSH8JPbFu6XvdV8DGRCddMRA4WZ86snd/Hw3tPgN/9F4sJIT/3wWBaWt8Hkj 4ZxbRgXFplUxUYLMj+hchUhBGRB0J9ucnv4RI22hkEGPlIddKnTFy8lOKybUoqmwpkaoNCZvcOQb H2fIu/zdyX+0Et4eDyeFpRTtexDU5CdPxkKebeqEWpqesNBzRJ1tqIFxE2QxO5LBM9rMcl40xyaR QI4R7jKLKaQeKQ9lsiQsEJVkVCUtAVfDxN0vhxP8le7MOYX4oaqIitxlNC3Fnf90Tkt0WxBDPshF 3KQTkpWrGy471z219SRyj0mimkiITWdqM58QfGeYzmSFVPJxnZtp5Ss3ikfFYbR/7ZzjTg7qPBLO U2/1NFfcAnQd9UHwgP/eUxQyTxgfeLGPpsiDZl4Q6huAfoRqoczm3DyJLDHx8nOo29tFRQq0OtpP JTfkqCx3iM6O8s9R7TNpVnB2kU7+KECZ+ulWz1WgQs1UiUd9nhEnObqK/oSnG3qXxBh6U1E+lKgr vEIHc5nUty11eHTsnVPPqTj86ZGqxZvq4B5IUWVOk55dVSkw5QFWiWnTQpoSFxXvub6gnnSLBjUW PKlpzbyW0Iywu+tCTUra9mltjDCUI2Azaj/BgvREv9IoDxenL5NkwV3yHKuI6skOzoIwkJadG2+O m63Pds6xpiVoTt1600y2dnt09Wxqh7paeWqOr0ew6Dg/Ss5yDg2debz/0yx3a1XBjUauyxvkXbkT QuNeiG7VnK8053nWo4puX6hVIWNLd9mWUrS7QA0wCh1ayrhi6rUvjKOKyGte264yRgezZXmrqlhW PgaZcO0l2A7Zz9RJcZ8ZPKhkR1vF1e2TwHYlG3XBWETyKNSlCW6dChncWc2Bk3zivJZ7axurC7NI PRqmIYcPS04BHtCVcJtvf/G1RMmKY4p/iRCHYLRZ7v2HdsRUcEHDC8RHilFTzRQr+7S749Q2+G7u q554Y3gr+g3WwuNcLIqYemHezrap0M1TAUfLVWa6cYFbHtXTiMgke15vdhaM7vkCqNMyw1OIESpt jjO2Xbu+uZf8tF04//+KZ90Sz39Hwajw5Oc/P8+SdX+EnF3MqNaYkXlin4QwPJ0cupzU2qFxFS2h SzPXa9ZVqJ7uMah/LK8gU9jU7AycqhHb6vY2+SzeHOD0eErrhuq6u3n9duZ4jWxJnxBzOLkJGnsK 2+yKGX1uVjZkx0Xduv111Yt1jYShuuey1JnPef4fkWmYQWYxb1FwbJW6iLRgcV+lv4pZNI3Fox11 F3pRfVVzGXWM8YtjTuJwPki1VPuS/KV3grrCocn1x2X7rXfJUEZ5DqslKTOO2+LkYjjmHM4lSBnV dEU1uLhPCj6M35qom86c0HMuLnEt3OcxGTl3kYjhlFcdhpV8pf6IZva4JNu52ieK1dZlriXJwZan kXrWzqvn9AbWTqaoATp4Zwz3od+cfJJhM8ZHLlOov9FMUj+7sHAYVQz/Sr1iz605m/ryxFrb8FAw KrjNbloNpa9Eazd6eeDFuYiWTPIv1RpxUMMiaHYb75DRe5DSZRvGdQr0aeCM7HNRCLsv5vaumL3u YUEI2+P+987YvfA/cQfpAv/4thi+8idhEyH5HvnQz8Typ38IO8gc19HP/iqoz321kAb22g+/JrpP ftrUYR2mF7/6I1H+9kdh/fBXv/vnj7D42z/69M+/ge/P/8XoP//9F4C393/0J4AGaAwEWIAHuICC EAQAIfkEBQYAIAAsHQAAAJoBPAAABv/AgnBILBqPBYVyyWw6n9CodKpEWq/YrHbL7Xq/4LB4TC6b z+AEdc1ePt7w+Dv6WKLv+Lx+z+/7/2hqbYNQcoZ1awkJgIyNjo+QkZJegoSWCodxloqTnZ6foKGi RJWXbJlzpgqco62ur7CxWKWqdKi1SooKsry9vr+Aq7iFt8OCusDJysvMWMLDTKiI0M+rzdfY2bLV uNLUTbrC2uPk5Y/cpt7fq+G6rObw8fJk6IPq60uK+vu78/7/wKCAqaZpihwKFFJRgwNun7tFV6rk kUjEDiOKfzD60WjF4hApeziiESkm08BKBZ9kQjhtocJ8Dtn1O4LpgZ43RuBcxMloTk//m1p0EpG2 x+dEnmdMfiHI0Im0pt+gNtTHriPSO1eFCM2YtY/RP12RbNWKqmgdPTWxHjrpRmrNQ0pSumw5lR+S tHm6ju2DF9BXP2GNvC1C9ObZo0CTBu7CNFWxti+hua2LjObiMXov3+kL9nDnLHIIa1Y7c/PoLnvZ xn1Kd3VrfFEcQhR8+kvtcn+9JrYSeujtbb9BB6eJ8kFCQ1Imr4tc9+7woLsBki2tW/je1Mw4l8Hu helx5U5fR2XOZJ/l6Ir5ovf05jj1vOuPXH/uSjsZ7oyLu29DXjJyWrnoQ1t8S7nBEkn0ECiJce4t pZBnOSXGhHxQMZjQhBHil0QTQryH/xZ9YoH4UTTGiUdMf7aQOA2DcRwY2ztkKcjFWwjVmNBNFLTC YBiY5ORhTf2UVUB739n4HYRK8VbaVTfiwRAa+CXpG3JNUOmaVFZeCRkcNbbYpVzszCZHaW9B+FEc SeBkyJRT9lbEW5gg5ExWcG1R5nslonmeTz0OWWOHW5VpE05bDvlXjR6muZugY+YJFE96GjpmhDNt NemZT1L4VZRSxjimip8yuiWYTRHJJUunojqZgJJuupZoyCk61qydMipnRHS+OuelQ3yZmpCCCnEc pjplFqmwt1IoWKuGHDlkFXkOkQl1ribGa6fMHsapY7nCBapcoT4GZ5yq+sqit+VxAv/nlK7BqqWn S15V0HwH5YhrdKXmpmm7RJhrZr48BVvAsNI+2ZXAvSYbYYjctofmoH722WqZolWK1LoFI7IXkINJ ytvFF48r8p2ukVjlgy/Ve6SvJbc8laIVyYvkYXF6ZiybgOKL1I73VpyxcJgWwdLPQRNNbpPzFaxp Vn+GyHDQj9YxKJDW7pyrxYtexdlflkZNYKCEQib22C5zTDaWXZrbZS4iwwFggJxtPXM/5FqcIc4w 482zVTpjDXTOQjfpcdEx5pxs0mQtHR2iG4r2NOBR91mixF33TTTghBsab9WFP67oySumLHpLWKKs sYUJqX2hipCF44QiWsscL90M2g3/K97aWarweT53fgXIiws+ltxA0Xh54sjDyrSqlWsK9XSPXlj1 9L0Pjvn1muvt9a/Ag072yAwJElmFh6St6shtv6GG6yfHvBvXNNeu9O2X544QtLvf7Zvf99IePPXH a0/OSiSsXM1PecE7UrX0l7fpYGpzx8ue7xpIQfhxLlsMNBvJwDe6cJROY/4y0n7QR74HxAR0s5Hb 7ABVri8V7EZHg6G8VPextRUsSC6kjY0GdbgdDopQRBqa9SQVJAMmL2N7YZys8OY7uVXPevPhH/ZU qD1P3Sxn3ivbBz1IOoYEUWUu+l766nDC1kGEigH0EqpeWKx5WWuNSWiau84VOT/5/+pNnyLSUBC1 Cy9KzYWpMBriDOW+H+JLcEP0HdjeZ7nLRfF4cZMdEzPmkfp98HslNKEW6egvOmaxda6RTSnCJz5G QvBMtvMNwdqIF4TJEZWAw0QfzxKaf6FHAa8cmPD0RDWpaWtSg5zWBNO0ufcMZpG+eWLz9gfJ2JnS fXhazCK7GDpqbgmTvupkqEpWnGqyjR/c1AXAqAWyVLLxZ72Zg+7slUzMqZOWx8pcwtiJrKoJDi+a +IgQE2m1j0VHluxiGDIP6EBHXq2ZWWsYOdGzLWKxbpPV7KKBsnk+LWWxlN4M0/owSkbY1SmgxCQo WXZpE4oRcp2OI1w+HaWsCO1un/8OK1qeTsnPCzovZsWsIfDaeUPtNXKIkfwoEul3U1k9lIMRPaqF UkUXMJHQdJXYqD6kkgBh0g+gRxwp9Uyqpp3tzplIxCEiRUojeurSnmo8ToMcGca+SDMrWI1RorRC sAr+FIoHnWBQY+WuSeLukhC9Zluq1MLXTMYtJaRMVUc3VzbFNTMklVXUoPjVhEprrbqs6xHrFTi0 TvR0M3vj+frpOUDllDd1dSIzDfrT4TmzsWn8GvCsyU2LgqupjjqsbnGb0fIEaIuwNarNGErAwnHV kJc1K1jp6qrv8PRhX93lPSXJ1tWtRqSTfGWmxJJamSnTaq1dLvawsMyiIhWTAJP/qGDRJ6hPugw8 udiiGqzjKpduVU9dFW1Kr5fPwnl3iXYkjHQlRF1FGpGQpc0sSLm7U5FaMIILzJx9+FZE2RKYt+ht WG83uNvxebi3Up2q+sQmTjO1yZxa/dlxKWvWuOKzvx57rNfmKWC0ynS7eNUZdiOo3Xcy+MI8LaiB w2vZzOmLaA3FolJHB9oNjzE8iP1wienijlBylB1HHikFUGyoyJqUWTTuXVpYOaQYz2xwFqoxEovX VczmeL9vTSC77OMm1faUtdVzbZGFPKBh/hXDFiVZSqLs5CwhFRGLnQY4rayGQc+NhStzboqNG6lz 0TV/HltT9hpF3DbujblrLimn/2kaTAsHjp4Gk1mk7Mzn8gpZz+5brYFnaWolny2Tgb5tod9J21tr 0hYdTTSJZiNBcqWqrjGl9PBC6BzUVa2PPuRulwK8RwAGEWmhhbBNGYgsVBulTgPN6oOHGeEpFhiv tPZn0JZMzSav98msA6yBqkmV15FS2Fa+c+46/WcBb9nPapZ1LnNyv/GWu253HvJ+ydutBW+IIuFG cMLfLGtYGznbDkwyzNgNqlzL+4PbJDRGFy2MRPPDdFUp9oFjK09X867imom4BIF6bpfXZmOqts7F vwvAhFsce+PedJyL5uuOb/C8gUW6r094ckWPSxNTJrctGQnkE8ezzzCXkVsbzv9nleus511P8OA6 9rsGixvjNWXzyr1+VUjpynqtvNI2GfXhiJIK5WV7chmv6VEr9d1NnmKizOmu9bwmUnH0ArwVcf72 VukcgVfP4H8nbvNOVbrxdF98zjE3qrsbWteeL/pDCyIbJnyHKob+e1hoRXV5Zksz+5aiPxXvy8hr GvJXLPstG+85Vs+c4m2KJ9kxmKFMSSnc1+wweQjNnMTmvYQkH6X6pkyev39M8GYXOx6JDJ3TEUay s/fn8Mdb1ELePPuGB75DU7PvOJtYDLCJfxs2OthntAMK7IPbgkQknf5vQ/7yl3/fhBLjcgxv41ul QBWRoCH+14DZAYAB+DoEWH/V9QYOEpiAlaEbYOeAHHgNEBiACRgXJxMgBygFGJiBIeFH/NeBLOgJ lmAiHwg3S0aC6SKADQETdqGBkdeCPNgLLwiDMQg6pMc+FRgbGiVK88UH7dWDTJgMQYgPTZcK+Udy 9YCESBhcTZiFHPiEUEiEtGCDF2iFV6iFZNiEXOgfMjiFYFiDYiiGWFiGcCgPZ/gNVVaDidCGeEhs cbiH/TeHtRBVFmiEJBhieShKfHiI0lEIfogLb/MQBliIePiGiDiJyjCCi0gIUfWFkEgVm6iAlPiJ jxAEACH5BAUGACAALB4AAACZATwAAAb/wIJwSCwajwmFcslsOp/Q5WNKrVqjD0XyyO16v+CweEwu m8/otHrNbru/ibg82rTa7/h8lUmNv/+AgYKDhIWGh24GcnF0CnqPkHdQWQYGiJeYmZqbnJ1jCoqL k5GkkE+LcpWeq6ytrq+wQqCoTqW2eKeoqKqxvb6/wMFds6J1t8dOusqpCcLOz9DRh8RzjtbHpbnL 2wYK0t/g4eJe1IyO2KTJ2+upluPv8PHA5Unopk3s+YuK8v3+/5no2cujTp/BOO4AKlzIUE25cwP3 MDnIrlKoi80aatzI0cjDiFMKUuRmMRRCbx1TqgSYwGQ9eyJH6prY0iKzlThzjmspCh0+/5n5lISs aZOXzqNIg/Gcc+snUIrWiF5EmbSqVVZLGWVb8hSolnNSK2W8Srbspawv9dDsCnVOnKElE5qdS/eP rkdr2W7TwnRoEq1aSlKtS7iwmbuSuOplxzftFAoUHtCaIlXhAwq/Hj8wvBKxRCWLGfc9B7m0ZFSU iRrSI+iyL8hUzECkMtgLbduQPFrBXUXIZiJKOqMOqTi0PmukSys/vQiu0UCXlUtvjblXZDRTjGQH I900kejdpf/2Hf5LFiLXh6RPOTOvcVE9syQPD3tmFtXUxx9yHUvBejKOFDCbb7UdcV0VpXVxmX5F RPfdf9o1ON45wtHS2HvwMSUFfd0x1/9TYM+9sSAm/MEyohnVbVfAb9V5AWEBsHFxooEtDlFggw0G t+KOKinC14UYuqXhfJEhaJqHylBm0Y1qzLhfja44OcZvKlLJHYMrQibji+phCQaDm6XI40ZK2FQc hmfyAd4dRxqUWiVMYsflICW+ImUYOtohS5xCcKnlEXd2aQaYOwbn5T9A+ghkaKANmVweRS7K2H1w ijgndb0E+gVV2ako4Bd+QjmEpjCK+iWOK1qp0V5oTibUmngUaZBLgNU01hqkQmfqKrkO4xuLNl5J 45aHZlmsjKimd2w8jUn613vIPQoJY85qiB+ul64xYJaZZqvgr+CO2UWoxLrobRG1Fcj/ZzxyVKFM tbusg9xjsOFlELztgiiXnBw2iJl/y205XZ1FdMhFd0cArFyf44GXIHAGAxfhp6BiqWmv0a17VaOO vLQovmgVIwWseixG61uSLdkkh1AuqN+dMY4amakuG6ldkfT6SwGnM0+omafRGfnyjcsy/J2D5XIH mcZJgdaxtUG929yrRz7ynliTEcV00ub9iV7LXsss6mXqQhi2p6V6FLPMWIbdJ5QUhqt0xFx3fS5S TgP5dIZ809JX1QTNNNLeIWuFED9n9EpegQQvPWzBhza+K3leSmm5qf5VXjTkZSj+4ORVOf0uks+a 42xjNau1zn33ghyVWInfTTB5Be9K//Ds6Onntr9cZO4vg3PujsbdD25efF2iJwmvU3xPqw/pI538 OuJkeI5745G3fOx/AJ9nhPBGH/81y2LoyXn1xH+N/FfLRNW+e0ImkEeQ3BB1F4i3hmE9zVDOib25 N1vb28YFJrPh7A5iQNj5ppQ+mRWmdO3ZC/OWcQX6tS9lCFGerdC3uev1L3sLfFwAawQ+GDHId7lj g/lSyMFBga4qELyf36IwqcUQLiggo1SIbCM7/tVuS7wjoLl4VrfwqeeFbWigsVCERLwtD0n4iIkF 5Qe9g2CtJ9fqWgd9+KCDwc1/O+Nhw8L4vRcZ8GDGE1YLAbUrJa4kh3prRPtWB7IgSf8vZTtk4xbZ +D2L7U6A5KmRf/w1mN0FrY/oehHS2KDEiymSjMjDIWoacbopDo4ZWbPIl+q1QtrdLIA8w50AFykL xwnIbQALpRn9WCNSrqGRl5pR9zgTQxlWg5JzRNOFTta3veCxGzzsVxc/qbbpBIiN4kHmwmikHG+s MmF0S2IaKRfMgNESX40CzE8mGL/Q9EE0y7ii4VTWiduUz3sKCgk51JkGiHzDnJwREBxRdwopMmJ1 rLPk4Wz1IXLG858aYZ+82EdJbt5Tgvrk5z4/VJOtAfSh4Mjm+5IABYpWVGr6FOdkPMRLHToUoiB1 hkTfx4e10BCj78ln4bSCQXZ4NKT/MIXHSCM4sjSddCQqjRpKgfLSmPr0GzO1kEWjZaGL4pQts2GL DvP306b+4kwRtKh8PnbThDrmm7ncBiVg59Su/qKWQpUCVE2nDb8ZByKvSk1X9MVUr7rVE2MthlTl Q1J7HtSl1UJrUm0olba+9a+ZAGs15hpUstoVXjltDm32ykuZxIV6gI0sJuJqDooudqBGNetwXHoH Oz4WmJINLSIomzfiFNawBoXgaYeDVZPZ5HCCEa1sCyG/iQrlK5RFLfzuCs58GUejF3nsR2dLXDzd sLK3xe1q6ZDVC6rVqrZSRFyGW9zq9u6GXDkHx3I71MP6sopP0eg6gutP65r3MM+NQIp2s8td5u7U ko2tX1gqdd76foKKWaBNWnA7VMyWtZfQ1QfWhGvfAoPhK3uwLF0p2l//7jbA42XGZz9LXQPPJQgA IfkEBQYAIAAsMgAAAEkBPAAABv9AkHA4TBgTxKQS9Gg6n9CodPpIOo3LrHbL7Xq/4LB4TC6bz+ik wmA4uqnN9JJCgTvZ8rx+z+/7/39rbW4JVH10dHZGTUggCoCQkZKTlJVZg0dSfoh1U4RubAaPlqSl pqeoQ5iLT5uJUp9HoQYgtKm3uLm6ZauFrXqInrFGs6G1eLvJysu3tkJ20FTBUMOgxddtzNrb3H7O TFXAnU9uW9jX3enq62Lf4WnT5Fha5/XI7Pj56Qn3ea9XR7rYszdKn8GDuvitOhOP0Twu51QNREix oimF5cY0fJDRHDZV9IxZHElS0sIw/xw+9FhM4hti9UrKnJnnZJeGHVm2FMImlhD/hR9pCh0axqaW lDl1ijz2TYmTJKEaEZ1KFeqQd0pwrlTar1+WgJeqiq3qDOsQpFsh7mRKT9ZKfmPjkm1KhE4RsALR uazGKtGqO3ID01x6dhzHtCHXRuUrFQSFvYgFn7Ir+QxhtI3zzpLYFNOgp2GV0K1cibKYB6brnOaD mlOaOKK9MsErkOdSwkSQXdnymC5c0qQelxFeNxVxMKp5L1m8iDbXe7iZ8JyH5ficY1c5zioI3I/Z MKjBORn1/fok60msm26C/phPL0FtM2ZVCDnbWr6IcO/Orf3RLP6VUV5xdcH2WIDzDaOXfIztlh4n ENq2GX8UBWjeHhYCmF5x1jXm/1xYivVCiC0OPQiha0wtmBuFycDm2FnPDEgghhptSIECcRCHzGLw 7cRcLJ8d5tiJRMYhUkQxApUZi6WUd5yMMOKiniOUPbbGdIRwlZuIn5RYF5GISNgVNuUANRqTlUAJ ZZTAkDGlEMI9xs+HP/0mJlRnFlEimCdyho6RerXRRJ7LrGmRhRnCmYtZ4RRk6F3x8RSal4XxCQJM PuJRBZIk6lfaM31e+MV+aDya4XfH4aiFqRqaEYx3P9UJE6a4TYjlnnyimGJQLXFqnKhZkQqgaS+K auGa7BHLhXXfCdsqm2g4ukdmKikkpoiL6ZYZihFKeO2ER8ZEi1lLbhLJd6x68f8oGeEJoUCipcDb RSbubDnILEB6Vl2unADakywDRfXtPeEQykciYKyrKLBoyFusU8o64q4YDruaxyIrSrfXjyN6NmSf B9oFE3ZEPGAPU4vEhN+ltv5RsR7OKpeFwg9D8vJwcmC8pazh8vXvb5balnEt9n4U8JFImGkzSshl +OSrFd18y5KDXAoUlj57RkvIpu1IC3Rei2vMyUSzHF2b9qWNM0JSu3nxcuBImODIQoeJ6cCc+Rnw O4E+0zKNanvR9hjCDjg40+e9HRvPXFYDdiO18vrzwGTSCu4zkRwO7cJZvJvoO5oHh09kPSkx990p Slr0Zl6vfnRE42YeeBdQIrz/mjqhz8jwGOUKbfVLhzHGHF0kkh3u6wuOrfEQMbuNuO6COzUzaxEf cl5ygPT0XXPzDb/4RKnvGrA1rBtgVvNfhrr5F40meqO77YUj/xLzc86Q9RjSQV6YaSgQWdmEOEzw hPezzkBHfLb40dE6FqjeweN2VnBY7q4yBlQdDH+AcKD2slSI0w0vgV5Bnt6uATDjORAV68KRi7ig JtAIiCI088L/AOihanVPa76zhZkC1TrkqSwbJ0STEGVIj9m8ASAexOGKtKOy8CFwIg1k2RCnGIb/ bfCIA5xbAb9hK04p74nFeIjRdCgwKprxK+YwYiZsqMV/gS02AcPc3nojOTKW/+6MeHSXFWOBxNOh rnUAhKKmxMeEXvFwQkrKYx79uMYs+jFc9qLc8Ug4JDA642s7sZMi8chIXzjykWHLWxx3JR4n0DGM nwAhMpS2STMiC4udZOAfvRgRcrDHT4vT2/LK1sohzjB41IhlCQGGQAp+xJZ46mEu8aWiXjJJTY1k Yyc/2LKC7SQYSKDMbf7Gy7U484wdnE8whTlMusGxJa7RJtjGdknXnSOI35RLOBs0TnIqaWT+UlnX 1hnCsCEPnvEUS/PCqRJpTnOLlJOOSDbFzwRKSpU+vGNAu9M7hyDRoIz8IAKz+cQR7kyS/5woRbdn 0WphFJRaawlWksdNf0a0mUAiDYywfMEKR37yoEp06TYj91IRxpRC8pBHAO1ZwntBNERHsmRP7QHQ n9IkmgLs40uIykqdjvCoS41oU52KjyAAACH5BAUGACAALDEAAABJATwAAAb/QJBwODQkjsiHcslk Ep/QqDTaXBoM06x2y+16v+CweEwum83XtGPNdpyllLg8/q7b7/i8fs//pq9tbHpzcl1YfYiJiouM jUR/gYN0W24gf1eOmZqbnJ1FaoJ4hJNPbliXqJieq6ytroagoW+jWqm2qq+5uruNCahua7O0RJWf f7zIycqMvpfBwoXEp7eHy9bX2GXNkGfDQg7Uadnj5OWwuGLeIODi1Obv8PDH6RRRa+H4+ejx/P2J 8168sdNHMJy/gwjv/OoicGBBg0USSpyo0NkWgQ8zUtzIscxCOISGgLOUsWTEjihTQvn4ZJjDkib3 qZzZkaWQkN9g6nxZjaZP/4qohrjUqVMawJ9IJYrDeY+oSSIXLhgzdkVBwgtWX2W9UG+Mgqw/xZXi 6RRfMRBxokYlOe8S2DxvF2FF1jXT17gg8EbR20jsOrJlw1Vyk1atWrZ+ifB9Y7ixVD1zXz12pMAx 17pCLDuGsnnKVyGfFZDiAglwYDWXvlU6PMQwYpl9uN6dvdhMZFeTydSjoKRL5bxCKeTOO1s4BdpE hHPeAhYv5pWQTuurVG1tlMOpTvIZnuh2K+6Kfl/PAr51eS3N/Uh/CAxL2inW3Sk6v8c7K/pZng+x qv+JeM7nnfcfGOn5YVpgL7Wk3Bb6QJEAHvjlYd8qEQbkxYBQTZiZZxXutf/fEA84eNRr66mxjioV HpjdEz2d0aEdGnbyon9CiaYYeuVFxRd9M94ImhAhRpEaVWW91B5aC9YCU2yOxMhJjz+ilwWG5u2o BVdhFDhFUEKUKJYBq+FXT4uPmCIkmXdASdxnYDi5Jnp3TRkneXKyeZFvOQa4BZZnBDnVJ4ipON2J SKbYYD5dpqkZd481Rp5rmekVomGjPQGpFI5i6BhejhIRpJ1RTglekuPtqYcqqHZ5WpdhajGml9q5 uChnccwGQo4gPDCncHoximld4D02562lLmdpS1T0559UthJL5xaT3tEMYolSyyKJQY1U2Ci0eDkk jF4E6ysUwtlHKlTPcaf/n7jF7pejXl89UKkUlXV2ZZt2gJmgJSySOY0trVISGL9n+kvGi6PaF+Bb VELVnJh8GnssZ71SscSFzA57L75mHPFvW9iiY9Bl3BZikKCgbInmweFi+tZ5vCZ33gMR3+qmnhK3 Bl8dDZsaRs1heAzYOv0mpqot+YUc1MrVkmb0GAi77C55teWsM6blNTxcvYuqCUXPG3OMhmkEH72y fN16+xDRLHfx7tTwvXyluqxlSG+wy57BtVoMq+m11/tB1NPTZq8oktpc4mNby9c9PEXMV8NXXrmW lkdzu3kBjrEYf79h0Mcjlf2IO0WKnoW+UojMOeMUQ0X1xFREOBzOijGq/zkXYD/7s+cQWbul0qua TsaXu7sttcPXKaz7zkLRDrelfClLoN9Z3k6k4WxdC11BDK4XctPGh9/68+O7jnmoaM0exXt5W32T 9aBRD19/8APfTva5xjo64jsZDDXr0GuJsBQgr7RUTFcEdNbEPoO3N0mFOw1Tjtx4Jr+dIXBDdUDU v9impNSU6BlKYkfqANGmWcEugACq2+PsJUDX7MiFEAxQpyi4urlRKl9m+ROhhFc4WDmNaVR5h5+S Yg0Nqupw39pfg+zHv6c9iIhQPJXiRoKLYByiRR+bThMJ8oQnRvGLGVTcFYthCjRVY4trA5/+wMjG OmyDdNrZlxmbqMYwwP+mjm3MY/cEk6pvHBGITPQg9/zFkzOtRHt6TKTAEFU2EY6oaFxU0hkU9whF WlJlfGwRWSKCRTQiKRoF690lR5k6FZmJjIB65PUGx7Q7JooUJisKD0lpyTcCbB8qwuQxEBW6a42G Dmqj5Siz6IzEbJJgZ0ujTIBIR2Eq0hemOUvBkIkJMwbyiELCSSAH5kxL3qIpobwi4VZJrV5uaQ7b lE43E0lMErayh1cc4ZKGhEbsrfOLvsBWGXWZnWSuTXrpVOc92UnPM7LyFntE1KvqmQ8vDjSK4vxS MapIJJJYlIcMRZxDH5qUfLaEhGa7liATY9CMeoujYARTv/ZnunbYk5MHJj0pSikSBAAh+QQFBgAg ACwxAAAASQE8AAAG/0CQcChUGAxEYSLJbDqfRIpUCq1ar9isdsvter/gsHgsdJjP6DS6S21SiOs3 eU6v2+/4fF7NP3+nUhcXTH0OIIZ6iYqLjI2OV4WIW4AUghdtZWqPm5ydnp9MS0+FbJSCcGpIoKus ra5ioqNrXJSVgnKpqq+7vL2+smmlU6dDubpax7/Ky8xkwZOAt2+aYwrN19jZVrNZtYPF3Nri4+RZ yYdmWrWV4GdH5+Xx8uTv7+nd0ZfT4fP9/uP1jkiqYooYOj91CDiJ9a+hw0bephwcOGaWwocYMzLy 9m3injIgLiaxprGkSVr5qPD7iEhkSHgnY8oEke/bs0WGEB0hwHOmz/+fw6R53DTQkMKeP5M+dGCq HcVEiDoWO0SEAEOlWOcJBckS3LYkLv3JyXpS31A9FO9ZulUl7J11Eu2MfWXwD6YrcZ/ApQSmlpC5 k7x+JDREKhRD79zSAayI8SqSXhzT9GJYchLLQi5AvmLYMLB7OEGvHb2WcMs8mN/6So23DesoQT1v kfqazlPbSdDYIk3aSU4hise8qS2c1/Au3+5mpgzlOJTN1ZqQvG0HdKZ0vHljVrXTah3ni4hDnLwF svIibJqTTyRbSfep1a27y5x99Jb3i9c3Nq4fJSA94LVinTNpgVTfaOKBlFh+CfbFX4NRjIdZe3jY A5UfB5b2xW8hzRH/YCIQgtgfNMsBOCIehtXjQEAWzjFLdiDYB0kVSJxWXILQNTeFNcTlCIaPf52I T5AmWqYAhV0AORdMYaxRX4yWEEcdYR2KEaIVOWo2oYxNkOajl0RigaQTV+IlZBJjciEKIvewOGUT aamVoSUVVuXdH8WhyQQ7BMVFYRuV1VVJgGPdZUs0Isao15lE0DnGVfCxKOmkRWE4Z5oVgZAYk1Z8 CIVhPtpyx5FjCqLkZSd61l6ZjWLmKZmYXgFppCpOKil1c7LKVRWI7YSnrno6EWsVw7qBqq7nldcp o8I6A+eKtkYrUGGXUuVIrwYEt2yZjhU76qIRiuctg74c4Zu0A9HZ/xsWwOZmrbbqcavOGB0BqV64 b/FlJbPNgjFrpE0YYAa6jdr3JifwksnvveyuApin+sDlyauMTDnwOQJLOy21lzQyoG/ABSYvJ5AV 61i7l+kbBsWKCMwrxtBqrOLBWNB837vzjhzsIrKFeiLKIjY4bsC8xiyQQEbLrLTMNnNxj0L24osn FvZeyXLBJ+/MxNAensm1bQGtePHS0Vq7CEySJDzE1cs6kWWXHXep9ROysbWnFl/vKxnQTfyLStgC j800M72qTVNdtNA99xBHCvt2o3Ifa2zkjUYdNN51HCy4MYM3053fCxMkJkmWzybdqpNfUXqRn9Bs NB9kN10zBa5rgf/tnZzkVQWPb0StO5nISrE6Kwr87nHYnGv8JlOy17kgWdDfobkQ9qBx9NLTs7Jp 9NyP4fJhMbM5dtIEe8LpEEhs3/36Xrhe/Vnkky2/pGYfZo6mvrKvv+3uB259rWXbQvOaZ7uQ7e+A NNoGtPwgiflhDwxMcVaVEEjBJCyhaQz8WPwcyMGNRWgUUEhf/ipIQnP47yCU6qAKv4cOMrDQcCWE 3sfclUGLrfBWNSPgV4YAwxhmZXoIOUS0NkgpENrMDHxrQg99mBTN+U8KgrshdXS4iCUycSaBK9p1 bjjELlDRC1a8okws1sIFEpGDGKSSI8IoRpPMkCrpCN8ZHXiw8z1EggB2bKNMspibnPixenOUHxl3 gUc9du82RREi0gIZu2wU0pDRE9+urCXHOTKyRdd4JCS7RzuuxM8dXAylKJXGxk1eIwgAIfkEBQYA IAAsMQAAAEoBPAAABv9AkHBIBBmOR4dy6Sg6n1AnZUqdRq/YrHbL7Xq/4LB4TC5nCcTmVwm9uN/w uFyoHl7UCrN+z+/7/4CBaEN1WmxtcolzIIVPBIOBkZKTlJWWTgmQjGaKnW+MjU9Nj5elpqeoqUWa oV2enptOrUSkqra3uLlfrFezIK+KsWldmrrGx8ipvKJRwInMYMXJ09TVe5CHRa3Oi9pl0tbh4uNQ BqxM2UJuv9zr6Olk4OTz9NXnS0/tn950u+AECeoJHIgMGz4i+vYN6yfm0aCHBCNKVCXPTkJZfByS gjixo0dJFdVx0+YrnkaOH1OqNFPsQhFn7/gUKqQRRK2VOHNyaSnyFT//QPBO3tRJtOiqlzDRMbQk 1KhTpwZ9LhRmJttBKDWfasXZUpHSpVXhrSPkxOHWs0QddAMFVo+vCxqmbsqaUsODYw/cxBXz4C5a TXFiwuvzTq+Gwy6jmA3k95LdZGO9UIh8gYLkvo2HZI6ymZ3CSonJDiZztZHeIYc1hPa2GFDq16ld d7a1N8zqLg9gH36iu/dL3Vf6Vu4LYvZtKO/UlATDJN/pIrF9tfYTF7P12WYe66JQW/LxIZaDq97c vbh1ENXPEymP/rudxnlvuyeJb7SY5s7Zr3dTcjof/ZFopwuAtm2R23cEonfFbkWE1wx8lTn4C1aE fOXHLPO9tNwogST4/4eAuXjoxQXYFXEgbwQSeOKIECI0YRTJ7RGKUhmW9YUBfYiYY4mo6IhFaDVq phqK2Kk4JIuahWbFfCEx11ZhW9QoD4c5lgIiLj42mNldoT0goRMrQnclaguCQWKSIqljSh1QanEH RkP4d9R/VvJ4SpZEeHkFBTyGud6YQiQI1xdnCpGXE98tF8Zb7SgqREV1DJJHGXhqhtkXgFpqp3pQ cApFgp6a4SdqKWZRqW1BXnHTcvp40WScQ4nRW2wIxcXda+7B9RpqJe66IK1SoLdrbrXClpllsHW6 mZ3FHQndfDqeOiKb0WBDlpkNPSoNG69uMSuDdux1HoDjXRrobM7+ov/foOroJy5xgSKaLpnQ7XHg eexGkaW0WbCp3E9doJPqL/btpK2qlEbpLnvkjqnBlyBw50S0UoC7HpjkzobZwLkBZ6oX844xIxet mDZwosQstRGFY/iYL3Tk6bslgXDBJyKAL9NbK7p63Gvux67w64QBjl5Lx2iNiFhj0Vhsa1PLCn+a WYJXUi1miTmD5+7E7gltYshAg2wGjlQdDadoWUjVb9nEyPmorFHzZjO0mUXG23EPQyxsp1vn+S2w Y4yqhbRen224KCWpcdzARu9iU6y0hOFyxkLSvd+vKM5rsd+8fV1Gx6/NzLjOQZMxKdtbWHj4i05G rsVDaPwDxuRSVy7/8+X6plje5hdP/PXoYAgeduluwYhcjNA0ft8ZijUvtpuUk/5b3VTX2F3W0jc7 ceFZCI8Fv9z3U3DyoBS8ISDSnOQI5PrGPTH16IIocRsPf1/vpxjLHYn3ZbbBN/D9Klkv5LI65QmC FrEaBfs6B73a2Q4pDsMfmKAjoVJ5jmsM/BzY7Nc+eclkDfhhwyzOFw+Wle9x7HNIQL7Xid84sHcb OxcDN9a3vsyvXnwiTlzYQ6zOTc1eG+wf/UgEryCC8CoEhIbqDFjAnUDKdW7rlrBm5UL9bQ9Y0IJN 14b1qdD1kHNdxBUQAeghXfkKKItKA9OGscY5NW0VC3wE2dBShTHo/40cdxwD0QyBBeUgMRKDkR0C 6SIMOaLlkOTAz9HaiDpXhaQ1/okUIidpDH+Vpnx/nMRGmhQeszhNipQMpcgQlxwkpsMXqGwCTfj4 OBRiJXbs45YoZ/mHTBqwEc1JXC/ySMrIqcFasBvg02hJTEqMTI316aPxDBanBg2zmawEZTGnWaF/ AcwQB9HlNRDmpAVS85vKbCIpD2G+SiRQCWhQ5Sy8Cc52ilNNvSCnLdmSOuQ403VjcJs798mFICll fKwkWSuhaLamEZKfCHWTP3MJ0Km08ZcBtREKD5rQiuZDkYgTnzaTWMBiOG19TZmoNC26FWsGcHwi TCZLHuEAB430EGVZgYhQRkrSsyhKnSj1F2nwic1W1OImsJwpTWuqFWqRppSjDNg6BSnSkBKVliad yR3mOU51dtML63zdT2f6VGKaDCENlUV9wkqRrQp1qF1dCdGUsA/FyTNgcF2eI4dyVqemNSdBAAAh +QQFBgAgACwxAAAASgE8AAAG/0CQcEgsOo7IpLLIbBYpFGd0mARNndisdsvter/gsHhMLpu/BFBS wpaA2vA4/EKvX8j0Il2SPvv/gIGCg4SFWAkEiWpHbW9yjxcSdnlikVl3hpmam5ydnluKjI+jkpOU YZZNSIuJBAmfsLGys7RFoQ6kkJNjmKpHIK2KrQq1xcbHyGK3uXO7qBJK0Q7AwdXJ19jZxwaKi7mR ppVv0qvU1efa6errhdxpSKThz+Tl5uf37Pn6+2B9onGmAgq0A41euXsIW/FbyLAhNW9tAqIy+GtI wosKHWrceK2PkIh1KhU0SASjyW4cU6qEdQtcSDAj6ZW8aM/ePQMrc+o0FKqUHf8vkSjaSiikVTQm KHcqXWrmHS55WmKSG4rQnrQ7RJlq3dolEaOBAilOo4rOnBohV4cM4Mq2rRanbrhIlUYWXbBfBJI4 PUJn2gBrbgNz9YpLS1CSM6sGO+sgL943wNZgrUZMsGWlhOM2mXs0cdm705R41czHMV97A3BeXq3S 6FNTYusCVvhrLJWnkoRouEBYSC/WwFf2JtIGsUWii0M3PtINDggNSGsHTbQ2uCcN0HVe+QMFi+s6 bIwXzQp6EfPmH59jX49djdchk6tb5/T7TP0v2QXl77L/eRbX4ckk22JmMcdIUaIQwd6C7VFTUXzz 5bPdUhOSBc9UA3ZTXjSOaab/HoMMjudYGr2s9UqEbWF3Hy0rGiGeTZ+5Zh5zMxbGnoI3ikhbXiWC oBqKQM5SGQHyGTEUjBm5ZptFB6a3XhPr9XXRcuERWWSQs3SHhZYateiOiKtU5NlstxzVh4fqYZFd aSbZBiGWcPqXCWgHNTbgcU6hVdCZcbnxpBP5xXjPNCRSc2WctfSX0m5I1agcEmlUBSahFWVWRINZ QJMVkiOCEJ9H6lSoVIu+zaLoFhNWuJ0D4K2CEj5jLWaanbj0+eEWbijWTWOw8qgWCCfmFCKgXJwa BoP1iSqEsvQtG8iJhX00koO8VlNpRkUNERcdf2ZRraTWVEVlET/KQioY525h/+x2ijJ7yRODGDuG u2AYwJedvrk6Ip3nEaaIrd1ikWsoyBnFqVf+8HooMvKesd99DePHRLvpShxIxPVaVMRISSqpr8ZD BOzEwLuehB5C+F6gsCf0EiGqsRUjE0XM2GD8hW2jFUQttuaNxyQaKJNs0hsJEeqpoTVzZfM1NHOx xEMcazjrEoTxati3HRdKk8l9aE1kYBSoiGgmCSRg5r/95rUXXVUnRRzWyZk19F00Rfbm2HiDwfas 5tRGUsdoEoiy4FynoSk6y32adxMtY0kXtXhN/be/hlsFqclxmYznOcvZ9ldltCwNSOOL30x11UuK Ffm+1upl8lMHF652EQtfRv966UzY2xnqY6muL+sKKTIZuATLTjfdtAObjehHP8H8pV7czo/03j6O uqOxYWuwrHWDJvuYajsmRO2faMCuYRM7b76C6hPRNPTwYapP2JlUgbbv5Gj/Tk2xw6jjpnAzCtrG V65PhG1BVogXoBZEvQTGSUC8w5/92tY1j3FNEmwqWgCtBYxxUOcY1CNdA3HntL1JgzMUycgGCZCb rWXNeJ/x4NdIiDuzycQjErQe5SpYOYxgbYUY8V9kzkM+GjruhobL4VRcs73yFEwYOPNhlThHwSIa EUW6s95mlBirHRIKdVxzROwS4YYMcq+KVyzdEk+IwuztUFZHC6PQpBY8QSn/6YNpRNTfbnMhLn4R eDUxo1029T9rGIhzRMxj3h6HliSozI9/7JeOgCiMsiAFcbMCXjmsqMjVIOYqkOwi69wjrrqlhziA WVImvYfHTh7xKIzEnu/MIjfEXc4atnobK61WmzpWspWutI4CSHKVR4ayb4Xsw2HQ4ScmHO49hjzO Ld0GAk4GUzB0iYaHQhnJSdXqYNPoD8lYwT1JUrIV1rwmV3Dhu/pwk5YP2Zyk2jPOtO3lLmM8RzrV uZU2wsOY3PxdF0lpyY0VyCbu+WMyT7JPfioFJ/58SkDPRkd8PEeQt0DkecgJQ2A6FJsBWsM/J0pR Hi6mjEg6iyW/dU6TNfSjQjoJKV8KgiaSro51vLKnjDgoyo5i5KUwXQkG2XAbzdh0gpRbqGk4GD6f cg2oQVUJaZDQi6MilYcwuukLnfrUqK4kCAAh+QQFBgAgACwxAAAASQE8AAAG/0CQcEgsGo9Ch1KJ NF5Al6h0Kh06ipcrSNHser/gsHhMLpvP6LTanCC4CUfJWCJfC+n4uhBu7/v/gIGCg4R7RnpeiGUa GkV5eSB6AwmFlZaXmJmaQ3xkFYpjjEOPkHtuDJupqqusrQZvnWIVaKJ3pESwuW6tvL2+v2Svb3Nn tbZ4RcNNA7HAzs/QrLuJdMWjj8nKXgPR3d7fhNNN1WaN1+ScsGPc4O3u72LiRrPlRKW46mXN8Pz9 7vsV6KW5ly6fmQEG/ClcGE1eJIFizB0zomtfF3YMM2p8xmcWRDASI6ErWLFkyQEoi2DcyLJlJYtl RpI0aXIiCJQrmbncydOPw/8vIWWaoklUXDU5ODGu7Mm0abwwxoSCKEpV251IBJIKWeq0q1d8QO2B mlqV6lBHQ7R+Xds1V5NaBIeWJXrWalqcbPMydWskKKi5ZskSQCUk5FQ5SFPqXdyS76GRqAAXLXhV yIYNQyLfcYOT0k7M3UAzRsPXcJHIkifvAXX5suCpke5O+gzNtWmoowWL+wgCdeqShs5Va00ccycC DiSh9CyoePFBon89iK7J+eUnRKw7N2L9QRfDG7BbRpJLiczfNDMblaOhteXiId0gvrkcuvhL1H3l L3NfzIaQF7R3mxAXhNfFf0UgGAoZ+zCAXkkMEPYGMnW4doR7hB3CB1d97Ff/iIetgOjFbeYMmN2F Iqa4gXd/sHgEH51E+GBFhDkIBzJD/MfIjjteNmAsEmjB4RoiNlebGQ/0h4WLSHho4YUH+lGiEQlt RUAdMs7olhzKIOIjjzvaA9MmRQZSZipnRuRfkyCmiIlDWuaS4Sk4giAgmHgyeGVaZpJ5pBpKguFk mwemiRt52cQJo1HZhYmnMaeNOeFdY5ZhaId/2nHpoE2I2F6gZuw3DYyr6QaYXFex96WdQ/AY3ItS kTXKTX9cKgSTYrCYJq5q8HqiH6BCiWKnXUxnoB1MOiThhJIt24mXYRYRbVUSZJjMNRtqql1+oD13 xAPtEaeBd216i2Jr457b/9oD0yVobo7vanpEgVF+oaAfr3Rh0Iu69DZMHarqyGqrkOo7l5hZDTnG ttxGkeAR7fVF74UhCdjXsSA8mSN4GQvLXcW2enFvYRpzB9XIa8RyIy5NHAeLHld6qaNpxijKV8xb EemfYcZyt1/J43l8K9Du8kr0z9yG3Kl19i6sNHl0qDMWbPy+4VuFM9NsTr+B4ExrGobuN3GrnD5M bKMiBxqxyWy3TeS47LIrKBnhqmGAAQxw+ZNuLCc6mGB3QmxiZrHG4YV8fKIRdpPuIjE2gSneRzTZ vnbstmUDTm5pqJynUWW1+/5ll1xwdFJwwdmMUWnqsdG3OuNhOGk27EQMnv/0rT6fPTu8DGO6uaWD iyGBY/q2rE6GEtUyl40271INSq9fXu/lbv66tBPuNU679RsTGa/lZDz9dNW5VNNMpfIgb87wqcVk vC1fh7+m0ODTXyTRSfqYHaHSj79w579bA/PkVIeXrYw80aNaAu9gLX0VDlsK013T7OehtXFPetKK Tnsq97PcVUJpSrMgGpZQOl2QY1KtQ+AXStfAMCzwcPIZHl5iN7/LiXAIPdsdBnf3uNp1MINICN7/ AtiXzHWtIidc2QP3ho+/sa95NYHV8HI2NxrSL2Pp8mF+bti9C9YPi9j7YYJMUyAhWlF+nVISF/tg wgIqcWoz8U1FVhinFMb/IUhbqdKBzPjFHIXRh30EF3XChSuNAa1kmBEjEQpEnctUjog1hNjI9LeG BKAiQqSTx43iQhG3EKWFfRMLGG70OkkIals7HBRxWMTB70HOlcYiTtB0uD9xPRKSZ1yaLPvABSE4 62WKQMwDSWcqWDgIk4CAI1iIEEFoMOmWq4AmMKT5B4OAgpOdVMfqlNkMUJ7BIc3MjTgFgUREYGOU MJETOuOkhWXWIZzjjOcZYEY8sdSJjgjsFxT3lQgqyvOfRySgPYfJumyeYirefNGCEGUPfwL0ofP0 pRwRJxxl8muFZkioIkC5t3dC9KPu89sBb6GnljEIKMFjYmXgCdKW+nIm/wcUiUzNkE5FsSdAqHuV rKg2q/i59KeHMGgKj2LR911UhS1jDzJQNyp8tPCdOgGqVPWYqKEKs6j5tIpFNoko7OBBFHEypVTH asez6IEcBDWeNhVaQIrYiRHVAOtkJMNSsuYmIYr4F8CuoQZPGjOhnHiUqYo5jNTU1a4Add5eRYJV g2lzQlhlAE4b4VcacS0Mh0VsXpgDlpEArLFqLazVoGbMJ1RWn1Z7YeI0O1au9nSmpDnfiIpX08Km IbOs1Usz5mPHtB7uWm4N1mD2AYcGqhYJuM2tUyzJiZ4ulq9pgNNlFQocBxEiucplSr6Q8Fzoxlak 6YmiJbCbXabkVaZTAw4tUmF6M4VqgrzlfUcQAAAh+QQFBgAgACwxAAAASgE8AAAG/0CQcDgkDB0O onKpTA4v0Kh0yhRCqyAjdsvter/gsHhMLpvP6PNgyABX3vC4/Kupa4ZvZiXN7/v/gIGCg11rQm1d copxXnYgd18ShoSUlZaXmJlMBpOIeot7imCQkHtYnkIDk5qsra6vsKlseiCgtYyNkEKmShIgDKhK qrHExcbHZJ1VoHO5j7tVwMjT1NXWVcrQocy8XHal0cHX4+TlrNnb3HR3d91E0mGr5vP09Vzoc3C3 ubpLwAxawAwbIs+ewYPj5OFq5q0ONH8Ax6iaOKwgwosYiSnUh2uLQ3BK/qkBQXFixpMoXeHriIXd QxC+fsFDM8mkxZQ4c/pRJqqlI/9eMf8FJIMKlU2dSJOiIcCToRKXRIICG2pmpjuSA5Vq3dqF6Sx9 TEjVEhJTprgzIs9i5cq2rRKvhzw+G/tu6p+ZDCS0ecPgptu/WrM9FdIupN27aqXtWeUXsGOMnbpB NRzRj9p+vx5rZhuZsENTUtWiVaIPZGYijTdbcnhB9chDe0zHFc1nL7QNS9a0YcA3tWtCd1qT0YUZ iwJK3zQcZ7JcyfHmhdh0Cy3Ik+1axQmTzGzk6u9yyqdlTzN++5CYUgPRVrIBNxPd3w/2a03hDO4N y6EbfwICfxjMmF1QXjiDlAVNTO61p+CC2g1DAFWGGBAfNe4tcVyFcl2i32BEFDf/niGIrIdGWajs cR+G/aFI0Xa77QHXhOYMuISMw40BYH8gLJcdiLBUAAmKQiiowWKGrMhdLSLCCAskwo0SCI0zclif dtiQNchZZQE5BIaMlQTfS0paI6AYUIKxIR2DUUCcEAkYRkCSVdFlIo5zEaFlbiWRZmCY1JzZkjE3 chjVIbuF+EVBM8EklyM4Dnmol0R04xuf1xTnZyXNNTelP3jIJNEqeJ03p3vJlfleRSYZwZssrIxX 5p1DbMpfF7B2YWoVspbhqhnL1TqalXskuuchAWXFxJ64scPoM3DimacRBJgy6R+3Jiurr0z4CsmG 2Gq3LXt2LtEkERSMS8alX1Bw/58gFZToKaFMVCbYHhKMOkSpeFCFmhdefinEi5fc0S0W5s5aRcHi EoHuGNAtDIKaCIfhMJl8SBgvkpUp+k5c3gR5L76nCPOeeW1A6km7RawGxsCNZLtFxBSbOSUFE2eS qWUhYdzFYeeFBfKtrN4DaUDd6AtImTU7h6vSOgF9BsxhiBasdadQNSy+Q4rY7FqpDA1mJbeaSqPT xmy4IdkM04kGbcFufBobGS8R20d0mWFs18IYKR0mYf8nBnThBcLyGWjb2EdetBWlKkRGP4S2v3ij ZtIh/e6tspNMIFy4x17k2vEZZkcZ8OFd6AVGohzXDbcaFmVlU6pZiPzkIAPWV/+eAoNXszlzVeTO RRuNv+vFTJDnLIah++Zt5LN8u7I7uF/AugHUMfsB6/OEvrlFZVoHs553YjD/OnwmBTNt9YJv4au5 Fya9xZm+/4npHwYU+iCBb2/vyaRbn7r8irvByjBQATBalcohHTrDlCLmnpn97SLYY4LnqhO8iATP TbLIS/gOJcCKbKxkXmPD+dDEh/EULHBbieAQFFAc6h0vM6iry/00pj+rbfBReZpFv/RWr74Qw31C mKCFbIYSIHYhCf+IW+piWMNeIKZLk+vaDqNIOUpZcQyFUiKnoqbF/mGBMR0cSJHKF8YrmhEtTJxF NJpovJARBIcrWgMZf2Gy1J3/8Y76S6Pc6sJGt11MdiOrYuWcRUU74vGQlMnfxnzRjSRujyp6FMek 8oQIKFIxK15E5ISSqEVFwk0kVTOMGzm4IgkIxxdjlGPOVBm7slxQk9+xmFnwVzdOimYqQ+nf3STn Lf7orQ2mi8sktGCIV8JSNcvhZC4NCRNbJg6SEsETlaYpwE+yaF9fGuExN6OXJAYEeZTh5COJIszk IdBZySBIMbfJpyzyLERlMYUz9fgLY/5xl0QY1yXXIhrXTc6e7HyMODl2lnnSEyA2XGMgsTHAoKmR kGHUZkAB402Cfs2gzxweQ4eBmYFUspDymCKkJqok3gwUnmMpikHHyboucQxRjRtV5fgKSdLf+KKi KJVnXebJ0qjxkmsf5ZHxJjfTKda0pPWkWs9UaktPytBvHyWZFGchSQ/+T6RHhZEptNc2dzDVmX3U H9ekWk07gpFVciwS1waZ1e/kgRfXOc1Xi9LTeBhSMHobI97SKlKathUwDohrpFaXmdCANRwAlYX2 Ivq2PN1Erersq0T/Oo8gAAAh+QQFBgAgACwxAAAASAE8AAAG/0CQcEgkEIiSpHLJbEouF6J0SiVe JNZrdcvter/gsHhMLpvP6HR4wGi3K/C4PK4Wau74OxE+rAgHA3WCg4SFhoeIiYBuDHOOg3l4II9T DImXmJmam5xci2+OoaJ0XXgbG3ukQoxugAMGnbGys7S1Q4Fuo7qqW5F6k3xDrAyugCCBtsnKy8xl uKC7oqUaUnJEw8TFrsfN3d7fy8+N0XPTdxu/qth/2u3g7/DxiOLkwaVT9tht7O39AwnyAgoc+IUe Fz9efvXx40ffvmP+IhKcSHEiGzddEFbxJUQjxlUfIUYcWbGkyW/iqkThQi0VQocPR8osdrKmTVkE jIUEw3ESSP83BIbd8sfO082jSDHlfKZxGr6fDof24zcFGRGrSbNqVcM0YSSfIHayujpV5EWMCLES Abi1rVswn5pOabknLKugY/lpkwqT19u/gLt0nftVGExLZvtl+0SM0dmHVNQGnrx18BC6C+1GXTyV s+PPFRrnCk259ORFRDi+PIxY7zaz+owh3FCBMVjTuNuiBqGwo+aoYRPTFPmbkV0pHdgxgtN664Xk 76DnRoNLCCpgzA9Lncnqomw51DqIl248FpTz6FcWeg7vOhlU58XE55K+PhQ09YWo91J9IWti2xXT hoDDGIMdEeKBMF5yzY0DICbPLSjhIex50wFm8lGhwX5bSJj/oBQReighhx564R4ZjGUHE1lludLK GwNCg9CHQyy4QTYP+VEMLIZUuImPzXTAYRnzDUlFB/Ddp2AX0lXRJAjPnfiFlJEFclZoKwYoIIHY sBFHI0LQiJyYF4VlDyLPGYnmk8qkiZ96VHboJIZDuOkkm2nQadh/UkS0mENWNcSbgqcUamihYbXT nFzrCckJkMvYaYaSY+AZoUqOOmkIlUdck6VwBooEKCiQWXeolJzttUpaFGaqCaRtukoklFDEqemR eEIpK3KQVPmHp3m55qKogAJz3BAnnjqJqlX550qndUiaCazJSEuGml7kKqYVuyJYyIkCSmGJaCxu M6BtMIr2/yVvhk5xijDatCJZmbc0im2PudZi7RiUiqFtrvsim28ZdOX0m7gVGExUoox1dxFzfrTr 7rsMK/ZrJY21em8a6Ok38CwBJ6TfSurpySuumG78sRm5bIGYYvts6VhHgoZH8cSTpOrisOXSOwWP Z4Qo4hTQTVjFBkZTW+N4TDLd4YJh7lci0QuabEUY2m4R8mUrk/GGXcxdFfNwYzf8MGkokpQYN1Q8 iLYaQk/trRQadLvk1XfTjSR6SFOBdHxsQhqFtFEk1y97HV84CJJW9K213UcKYoABMT3UmoHxlvfJ bq0haasdFZ+rGIGhXsXNmfhBTjTK3N4Z+etzXwY7grvum/813RvfOeG9W4OYdxpgsgE2i5ZwidEn x4AZ5s1SXBcalzMJqGOzfXKs+smrY589glY/uXKuf4PYrbZ69vsF4/Jd727XXRyBZfGBNLV5w8Yx Jjz6fq8yuk/RYx5Zg5JJX+7CRAVIDYxNBxwTFxx3JA5ZC3/aSwP7uDXA1EywCtA6npf8sBTvCK88 8JMXCD4nLFy8Rmc06Z/whMc2IqmvRgX03uPcxQU8KY51DRQfiUQEtS/kJ4I+fOH2zMCjsaBGdFYy AlQccxZA7Acd1EChixYDqr1syU8PMgu/hPi7OskQU0BUINUQmK/a7cpw9jHf03oYuzD0Tk7AM+IG RQeZYNH/MRvW6QjpLDZFFcqmCgPajgDBYKkv3gqGNSyj98o4pDNGKz1DBMMbD3mGdcjmZR8cV1T6 +EHjqZB/0bNEbV4DL2Ndi4uFDKN1EFjDbBGBgTok2g4zcUGPVVCVYQDUH8WFGH3ghZOZk1f0jOXH kTTmTGzpwiQJOAVIwZJ2soTj46TWoUY2kpanVNPnakkFB+hSecFZxRK7ND9zhcqYf5Ji/9YWv7cB bZqEjCHRqHQKGw6pbufD5fgaGSduStONkKPWMytpyfgxggBog8kv7VdOK6Fzj5/UEtsYRZ8JpjKS 1yHfK20YxifVzXZG8qg//ylJ1SFNShBEwzcTWpfiHLRy/+cSJgslsrYqMquFYjsdtJTJw2110WO6 8ymu2DhGoS7NafsMqnhISAZuvlFuddjkADxiptuwZoo48oxMZcKQmVzMZclrxnwkmbuxau2WZ0Vr m9SoBphccjlg+U8IkaiNhhhzODYtZvHAOZ2+bmKTYFpOMPbBGmKZ00DqNGG4imkMRSXveX6NbCIa 5LBGGMcjfIKfBzfL0KnILLF4jQxEchZAyZpWpZvMGWT4IFcNbvaOW/VTWmRSrz5plrSnzW0aEtAc qGSyNaxtbXBes7+KedW4mAttvXSGUJHsVLfQ9UJzjGAcy9FsnNq5rRZpMkqJkIQu6ASQoqYX3fKC IUu99f9Na1uj2TtekSTKpZvFfsPZnJn3vl1Ib3nCeV1AAqe96ZRIYtdQoMfshaL4TbBd8JKXt/nG Zf817CLmW8L0XmOPAHIYG86p4A7vQR97AguCsfuRO4Lqa8hlIRKE4SlVyUum/PVwh/VbqgePmMSW SyexHCRFC8cYuVkF5kyeK+PTWhbEq3rwevMC291UkQtUBLJMAykGIhe5vDWmqkuXDOAgl8XHbEsV lYVczCtD15vv+whCVtNLLucYq2orYRODmVXQDtPMueWxYH2TZtW6mQELbSgpK0xX+uqEsTTF82lV BAoRjyXNXA70a5OrKLpqGNF3VrRkx0EHDaAY0qL8M2EjtSpo6C02r5hOtKYj2xQs9WEdW+YTSPYo rNhyNtVlXrVbggAAIfkEBQYAIAAsNAAAAEcBPAAABv9AkHA4JBCPyORQomw6JdAo0eisWq/YrHbL 7Xq/4LB4fK1UlBr00Xwmu9/wuHxOJxvqoDZSw9/4N0psFQx6IHd4iImKi4x0DG9maHwafxtpa2yN mpucnZ5KA2ORkn1+SIJHA6qrrJ+ur7CxV6Fho3ullhqCbI9YrbLAwcKatF22R5OUppi9qcVOVMPS 09Riz1iRhULJypjaRKrV4uPkZNdW39vJuUOZTeFb5+Xz9MHyW+uA7WYM/f7/q+oJHDiQQEAn7pBN 8sNnVxV4BCNKLHdPSDpuyyzy+4eElcePHgUImEiy5KKKtxbmQvUQYsdnhEaJFPDRpM2bYFAOyacv z8b/f0BBCj24L9JMnEiTxslH5Ke/l/eIzpo5EoSAaEqzan1WSGXPY6B06qxyVKtZs+eYNm3pxCWR Zlionp2rFePXdM6GgrzSs6kZVWXpCsaZMY8VvUNBKelAduShwY0KQ/byzFKWX0rgbunAmbMGlI4n L+Lcl0vP0pwqoR6Dee1ht0NgJ+EqpLNtxkJCnQstmtrqLx0ufUGNO0twIh1KX2P5DnFNLRtsg+Dc 1l1VOsJ7e9GX/Uv3JGm+hymNevVYcM49nrpSPAnqYoCva7dJXBN5JH0TaEmvfj2IUAl1tlh7sw3x iEjzASMed3zF8ZsT9x1RGoJ45cafVBZVQR2ED/13/wSCCQbzYBUjbmeahPgZyEo/UF2IzRDRJaea at9VNABcIIYYyyUlpggHgQ0Soc9pSQBkIWIepmLcjDMW2JJ15+nICJAkyiEeh0LWBiNscDEg239f vkUIEqQxqQVYgQAmpYLQxeEZdnkNUAFKKzppGHJMVpIGfxXmZpGajPzWo3G3NUElmVb0eKgbqKUx aCfawDPnc0lWEUmMef7hi5f9dSQEjvLhAQgfWTRKBo8baqgEII8qsqgshUTJCgRrbFNbppIdxgUt B16VSKtazvHqdGQAOSwIwCL6BmmitHEOXHSCI2RxuF65Ba1tyTlEjnX8Zm0Sx6LYxbdBlhTuLJVK 6//puiBgi6wQqiFbSRlZQNCnKnpwOwewh35HLgj/NnJuudXEigS0BgLVTzHuwmvmO/HsZ6BVNHXb JhY9ljZwNcl6EulhT2HTJLqXedFGqHAAqzIXwnUsi8tdwOxabCBr9ulbEubaIc5Z9OkayoxejLEX AQ/3qyIyt8VuG33a7IbP/jnZC6AOajFwxkklDWts+FrkNAhfi0P1G1qbiE85ZZeKyCALG4bmfrR5 8gzQ442x8WJE3w1eyks1soo2vbw9MTAAvsMPxaU+DKMWGqQarNXgHkGl3sg4/vgYaavaiD+7hO0P w69dWEHDEPuM7yCIk6E1bq2u1nihkXNctd/tcOT/0+HUkA4xEfqu6bsczO3cbhUa6N6E8Tl9SPfv zJN8JzMstnSjkjMrxq41yjevfRJQeyP4wV66EaUSyDfR+/a/O6D0ETEl5EvEPbOWhEhYoc+8z3rs 0n3C4w8ffxLlUxf7wJY6+zWPbQoL3530t4W2Wa9kx3NDL5ZnQO2FA4EOaaAC5Uc9CDYBRxW8X+k4 J4iwfXCDElufEEjXv9mMLYQ6Qt31YqKRLjjwepi4QgBxOJtCUBCGUipchtrhBafdw177g4B45HGe 3QBRShXaiBkusb8i2ekNLYzLE9GHpu9dwWYN86Lz5PDDLWpHiqMQ4xd3ZTxOhclPYvCVGUWDF6Yl P0SNTjAh+WRRxjnSkYhD/IIeBZjCDsbRjyGsYmbqJYw+ItIm6jNGGEyYxXQhwpGPNEuf8PjBbBVy EXLMZEmCAAAh+QQFBgAgACwxAAAASAE8AAAG/0CQcChMEBnEpFJYGVae0KU0qZlar9isdsvter/g sHhMzh4OZelzqGkLN/D4xlotpu/4vH7P75fPeWtrIG1ucm91VxUCAn6Oj5CRkpONgHhRQm4gh1xo IAeMk6KjpKWmQ5WeZJiZVZxzZkJogKGntre4uVypZYOtm7CbW6qfs0KNusnKy6cCZ8RerJqHwVjQ z0nIzNvc3Xi80SCDmsCIw0nPlkTa3u3u71bgW1BNhImH9dbQsulK7PAAA3YjIE+RtDpyNiSyYmyJ pX2oBEqcqKzglHHTYFVjMkUdEXWeQNWKSLGkSVLOPlnBiDChllkeVQ6BeIzdv5M4c+ZBRjMKOf+X L2nGpEkSxE2dSJN+sejE3puNQa19xFLJqNKrWLvsq5fRnBmiM6fGPJK1rNkvTSpk6LopH8N+UsYO BQEhG6qjZ/PqHBAWRAanCRd2xPY2LGGZsqjqXZyU7xJObuMWAytZ6hK8jDNPdKwqcNO4gCgn5ocu SYVqEJFhLklBWWsyFF7rdQwGrhJVIVV6hAh16jqrfWRPEn7yghLjXC7EJg6C+RLnpAQXnj5zrJLe woYg+b1aIvRT2MGEJ/J9eGvlrcvfFs2PfW6YXjp0HF2zO+zl+IMnQ/6F/xL/zwkhnHzyDYGfbAcq USAXCJ7jnnUf7QMhRxos2MGFGC5Y3WVJqQf/j4YKXlHeeF4AGKCAIFyAHHYpXXHYYH1JeN0QIGZI yIaIFYWThybxyGMXP57YnBAgavViZcQkmeMbRC6BIToTKhVkWepNiSIYDQqjIhZNpBMlfUvWA1Fk TkJZDGNWbqMceUlQYCKbVqQpRpYOfeUibn3lSQSBUyz4EHy3gbAdSQpQJOcyblqx5hRVDmcgEaih QeYwgM4lHmk4doGMEaXk50V5y4kYKqOjYlnqEOOReOgplKExqFi0HElMPUXCuJ4Qr2bRiH17vJnF gquWeZyQjBJhYm+xtYlFsFfMUSsYBixZm1FKQpPPs2+IOZiSWvDKB37YAZtsgcyFG4Z8p3ah/6F8 JG7xmqd38DmJjIESUZc4TWIBS2gRGnMNOv/kKgq2DP43rL5a+CoFqEnMkay7ABEg1kXbCYUGBA3R GEuMIGHz4r1b0NbpniKyOV6DBOMBXbtZvJsuNxmTlaTF7UmB3TW4/XkkQ1OIPMqUzA5ZYjJBb8Gy F0QBamsx0qGqZ2IHbHevl/zG0w2dxZKxgcILa1H0sgPnEfMXgNRl3b6SNfTeZJbqdoW33z5aMik/ tpYy2MrK/Q6npVWmz59EVOFxSHg+pFvOO4OpOHCFioJ113jcDSQkX9sSc8Wd+AZ1oIXT295umo4M cbxjVD65JJKTvSR79WKqBMYeO5Q068BxCP93Gsx9JxzXQvC+Ra3OoSssbHsA78fYX8pOF+fVIa/4 zqJhtqujekOu8WMgFMkcgKkLzUX3cSJF+510QXQG7HjqmdsWDIAMyuK3g2+9Eg9X36TDPiY6BXoU hNcok3cw3XMEOJ/xTWd9MlHb4v51hfZd7RR1Ixb1cmJA8rnvgMprmmb4gBzfKaokHtyCxHiWBsKY r3nSctsFl7LBFp4iWtQhwzNAhhhPmG1DFdzC7VzIQ4mULYW+gU/McmiXK4ywh0gMCISGgjgvncMJ 70uiFG9BxLeABWefgwgNhbDF5U3xi5YDohigVye2VQ0LGgwdGNc4huR5AQltOxy/nLiELireolsg 8Bkb97gKMMDRfOtzVRbV4EV8kSEUeuTjGh1Aij8uz1+agxVHhgCBNJ7pku+BxvQSqchO6okrdygb A0FzhnzQcFLcWt0UGsFJTyqSJpY0Uvnmc6YJoTKST9NR7VzJS0kATkK2UcItDdO6Y0hher1MJiRm yMQXqUIDGIsRLsewQ2Va00gHuGHNZlVGMSpwKY044jVb2Dgu9WGGOXJVXSoQTc2NUowsHKc8Q3mx GmazhvQRSgK/Mc9+yrCeJszUaAgnzZ2E05+aGVQFyOHLnNVSNOkzqFEYUU2EtiMIACH5BAUGACAA LDEAAABJATwAAAb/QJBwOBwIGUgGcQmqVJrOqHTqZC412KwwSnxWjNaweEwum8/otHrNbrvf8KVB cKhD7nFiZs/fCzcbVhsZYwJ5h4iJiouMjY4gdHZ4eX19f4FMhGQZEI+en6ChoqNEdQd3nXCVfYCt GxwcgJpiEJKkt7i5urtCpqhvq3yugLAgs0tPk6amAs0JvNDR0tNmvqlrwX7DsIBWTyB4y+J1htTm 5+jQk2iE2cOvQsdLqOPjkeXp+fr7iNbs2SBanUHVqV69ZuQEGODHsKHDMARA+BuTTdg7WWF+GdzY jA6+hyBD8psoBqDAMZ1S3tlosOMBlx9FypwZjaSeiu9iYRpCkB5L/5Ydg8akSbToKFtLTO4cIg9c z59QhSIcarSq1UQ241m6CGiKkKdQDV4DJ7Xj1bNo3xjxZezmnpwYefYsGFbsul5CIaXdy9fMgEin 3GbYRktj3Z8EwQ15mbev48dFAHeqRNiYlLm1DrN0au3aWCFUIYuuKjlewKVMMGtGvDKwynWhR8sm zXZbXKdzV497nTkwIQ69Vi6eTfxspLupVeuuR5CtaQ+9TtUazhd6Og8air85DiGDzlmYJS53Xqv1 ZyEe0nvY8NL119hEraPrkH1NBzYPROW3sn9J/v5kcBfQV5j1Nt4yPgXGhHzqkXXKAbeoJ2GDjMg3 jYX4tTFhegMSsf/hhwtOWMZ9S6AmRjm/4AbWgangsdJd3oGAoYzpdQCBIZ9B6Ml6o8wIjY9qBFIf Gh6Q+IeMIOwHYEA8EtGfBtABWKQaRoIwpBWSFHggec15NiCQ6L1XiihgNlJmLmdSuaQYQJbppo9r IlJgayzylpmXS3Sg5558bnAjYOXo+EmaihBKiqFMmEiEoku0CaabijxQJREdtZhgnSo6ZwUsnBZT SjNDBPUgT/C9geghp4aS6hgaTDqGo2y+CsoydHy1pSRZ3klEd0N00CmnewbSnj0uZRZqhYees2qi VqoBaxhgPrDsGK4imJJ44unWm0p28NQhCL8C6ysnuxEbqKCCIjL/rRvrOtIuE3FCC+2j1DbpiHST XGsgUN0SaJN3ewIHHLiw6GnrRtElVKtEi5mVx7trQLyIxEMwagWcHMpLhr1n9BevAt0O4lR0CYuz xEcJehlIkb4SPAQHvu5Uz2IQZiYVhOkm8iGFHqInoRgdiBgmmw1e2SjPF/+MpIdCH430w4JAOkZ+ FKdmDJ7i0SUOndHRed7L4BLB6dXjTeUSw72ou/OM66HWZtTQVhm0FUHvFGWjGuMthJQLXhGG0XHn eXfeZVQNAgEuSvdVwnQKShd3dZTIp8tiD7zvgaJiCxrUZ/iYcc9MQDkjlNAaPbqTSx998eoAUl0G 4PMKHe/QRMpZ/3KLjJvsr3M6agJdp2ETHEvJ0mlGM2MIGbs5HIj6uAHbsepNeOp/c9yr56tnj/oQ sy/oauFpSDq4GwyktPXi1kQ+j4FjcVBkMQMLUQy5BjEBVcKNqa+XqbVrnySYzyuRB2ZnL2mVaW7T o90QpuQ/5rFhWdiBQ/nAsZtS2GEZ82CcHjz1MstBBQLZWY7ZQKU/B3ZuelIjwvcW2ECmRU96C1zb 56YGLxj2L3zvMoABXqO74+lqfdlSnDHi56mf5O5+JqOVwxTEvxM2MIUKTJp/nschKdGrbzbUUNNY GDENxeE1QUQX5DLymXVwYymIodnlAMMMUxwMeYFKRc5uCL4niv+BdKAjWhioqLoEUi+KGfJPFs0w LYo1B0HHSxsZg2geClrLeI4kB8KiczO0ScRhTiQkCoEGvRfyh3oIbOEfaTSoB9LQj2tYkRsVozmU aK14zGHl8cRCvKiUpVbqm2MdNdnAUPYxj6KEYQD9iL2/ocqUYVjhKNmAOFUy0VtlaFzjzmdB3SBk WApDCAXPlktn0RGY6HGVnoqJRVZZSFpJKtEyPdeBJQ2Tc95kE2rEd4ieEA99z3QlIrPFzyUcZl8w gSN3pgOJcyGTl+WsGIb0hMeEgsCXXGThkqBHzkV18phd5OSkGPjF3OxTDN+wwivlqKNyaYakAr2m 4pSoTf2VKob/O3NoRJ02w+qJaE1UfBpNrVPRnXIUnmkoE9UmBLs22GlfQBxIGMOIoMCgazP480hL 6XRLQ9ThGy/1RPfesNVEdJUfX02DPcOoL+SQgS72GweWJkm8mzHjZkFpZVa1Q9eOenSOX2sCLVpZ y371NXJJZKlKpUJJs9QMNM2ISF0Xu4inMFKWVkOJJWGJM5MiLLDZFFXkMIABm5nlRoKaK2NHO5Cx bqsLU0jMXrd2uVz10J/q641bA4MBxC4xecsjrW7dcNTTmpVAefUWazcCgSfQamb9Ulho3ShQwSqo I2DYrXTRYE+vQXZXuHElI1vbrbCUTJsng1BjKFiLuBa3AtCd/656z6ol7Ip0rBm5HXc5wpGF2U8o F+wS8kK73v6y9xeNdKVq47tdSFoQtyCorT/PpiI6lKe8oCqIfydstbH26xrgCc9eC5zGbR53CCEV Qm0Z/MYWiaOloKIwhXvbrXVkWMPBpWb93qhLJmBgv6H6rDSVC0cVT9gBvZVlFLohF5XIMsa8mwh3 Y4Nj2z7SFym9ZXR9PN25SAR3pilyvn6b1lVacr6VIsKNr5njCHtYsFWNK5WrrKIXfSXEuzLygEVK Mtj+NcfXAC+Py/PINN9yzeqdIIy1q+HVpsuIIt7vNVPhEnxtqxN+riqg/WtlVjYFuADmsp1nqTsF SxJFPMZXU10jTWoBKHbSjLVUilJBiN+qNrjz6KGX27o4SAw3IZktdZpPjeq6fmYwk9CEWY3sXkPP mqmSdOQ9ePLWguqa1L3eLasHI0thE1subYb1Ky+4Gc+a963PDreao72XIAAAIfkEBQYAIAAsMQAA AEoBPAAABv9AkHBIHDCOx4pyyWw6nZeodBrVaIhYYSXL7Xq/4LB4TC6bz+i0es0uW96YuHw+52bu +Px9w+9z/n9CGVwbbYaHiImKi4yNaXB0kV54XRl9G4CBIIMgGFgQEI6io6SlpqdqGBaRdFl6Yn8d HRxfoKGouLm6u7xnq6xxrq9hml62tkQCvcvMzc6Lv5JYg5Rdl5m0nETHoF3Kz+Dh4uNDrMJ66Nog sbTlQsfk8fLzywRZ5kPp6JeYgBvq3JDRG0iwIKk6+e6QyZQlYDcy3wxKnEgRi5yE+vBcy1TIEwiH t84IGEkyYsWTKMlVIwZo05CQokymnElz10osG4t5Elizp8//iQNcbdLHj2GGnTzb3IL5s6nTRhaG cWn5kuk7Qw+/GHjKtSuZqAqn+qsa8NABeC6FAPDKtm0Yj1kYVnVk9eqQtW7z6u0kJCeHjhbqIjqA xYIQwtv2Km4LV+5OLojVHJjMxROHDnA/pr27uDNNxNg6CjZbeQgHDx4aqnN6ZZwsz6RBzBISp27k NJNz377lMTUZvKKsCB/eWlFxcKg7rOkgXPkY4WCIS7eS5YKs61+kCzkOIkoYwpxU5fKE4Rbq8+fb DUEMgTBwRtxJxU+pwTmW+WJ8D8F/n4j9IfqNESAIHvzXBWLiOUIYXAuqYlgH6BGI2oFZvGccLvwt k+EXyl0A/wJ0H5YB4iIbyobFfx4aOIQAuqHCHl9wTQighKip91Eot7jXyBUlItIjhiGqQR0aKg7Y 349kGKiiiiBs9cVtuFFWGoAyEhGhMZppZuEhPJ6CpJdBpjGkiUlmkWGXXjAJhpJZ/JcACEHhdcwE UEZZZyflhXJagdf1eZ2NQshkl1oA2ONjmPKJg2YZ3n3I3HGNcmjGolyoKal/bRJRZ1ZrSMkFBI/J VqUQ2A1h2Bm3ABAUl4iO8qUplJ5RnKVd0MpFrFgYGQabZJLp5CcPjUbGAYZFVpuVr50I0UiaJgbC lkK2Gpyi0orYmq6XkoErG7zqp+ZZ7XEzBpTk8gXBgzJic/+ZLLTc6Q4IypTE4mQwQYvGtoZcMNx2 1L56X2uv2mpmtTOa4SERByM8zSe6jeZuZeXlKoS664Jwqhe5ecJsQ1nq2AaSagpMRIbojSpxGNjO ijIYCe8nRMtp1toFvtU14hGo77SXm7ArdlEbBBnsOTHFxaghE70XjmEpfv/1uG909ZncWsIaeLCo vso9OvJ2I2IB8xrXekEzF193utk2wqLl80e9pUY0VWyQ9Imz9j5HsLLPmZwItgXPfCQXRhrpocpq WJ3d3fcll8gqFuVsDKdcGHYaqW/TcrEXgiaTTOYvqRVtjx2SUTbfMiftMndqls11ov6SPoahmZWT Z4toQw7/xttg1Mm5qfAKulSWdUeH+BBqzud6L9yNncXxZYo4fCOGfhFYXSDpTFlksxC9mheFhPGN TPLu/NFIwYv9fK/9ZXqr+tl2x7z5W/srhnbs2y0/IoLh2N6nIH0Bd+xZeFigAniAeeVGXiPxFAg8 5jzQ+a1+W4OgGUQWwdPdajpjagMFLThB/KnNWcCqHodowbP1HJALgspcvLBQJwDsbn0OXJ8E25co hcVng2IjTqUmdT68sUEBtgNWYqqXlMaxASYbywKzQJFETZ2FCOX7264eeDIxCExgqpNi+nKBwxDd rxS/y5n+RDguAVZiDC88TIWaNL/zFc8QTAtDrLI4ny9y/4uH8uviGpIyRofE5AtNRCCLOIaFKPIr hgMjA996dIH3Ac5wiRxCFhXRRXxlaJJkcIAfnRWSiN2of7lTBAK9B0LOyJFUfkoW8ai4vJY5sm8v Q40rvaa3beEncImoZA/dpwtxaYaIttBNuQ6xwi9UYDKCHGTnniU8pbESYSVLjXWaBwZsRfNgdSQb KXSZIT2iCgyG4clSgFnChhgQDBjYgMaSeZsmshBpqUKeFTA5Mg1gUjj3tCPX9ImhDCKCAZskQp74 R84AeiGd4+rZAL2RzJKIL1XRg41ER7GpY8CFnEXMUmkEqBsDFrB38oJXAEMRPinFc6IoNQQQrQKl PEEOo/+gUGCzwOBRYQpTbihUYvg6d9KU+jQNDGiIVcQFwIKWAUq7+4bGRLq2A23Kcz+N6jcxVpab wTSjXxhEGo3FVBZiIY1zY6ZUxyqG6XFjNxYly1XL+a7cffRJanSiu14kVrLaNQsOCMM4YbLWD4rE jJLRHY6getfCDmqZtRMEUvq6P8l8AYC0eWdCoWhYwxKAjJ0oImOPIcwxBKOpALyNTXcmU8TWtbKo xVI5NstZ2j1Wc+74wHfMCFbCpva2n2QKa1ubmzSEQrYCZdhkw2BI3O4FZ2ENY+12azQsfAC4PWvs IlRl3KhCdhuLFSNzjfGwt0a2lOtJRHGrm5fr5gkDgxBgyG6xGgboLjS8YgAsGMZLXq+ACoA/s2qw 1stWvmDsqIegb327AllPnMql+12vQRnqVcS4cxQCHnBT7IFePHWhLLll7YJDSUglNiLCEm7K5Qaq VnjwtwzK6G8pQBzigQQBACH5BAUGACAALDIAAABIATwAAAb/QJBwSCwaj0hjJQnSIJ3EipQ4YFqv 2Kx2y+16v+CweJycTIgWjHrNbrMzWo4c6YZjBAKyfs/v+/+AgUNmaG6GaxmJVhuMG3KPc0KGkoKV lpeYmZpIZhYWV21wWxxHhp9CB6kHE3mbrq+wsbJCZyCeh6FckB0dHIltp7QHRa2zxsfIyV2EdKGi WI+8Q20Q1RBmw8R4xcXK3t/gmAR4tBO4iKOkQ74Za8HCSdvkIADh9vf4fmbnGLpyHdPUvMOW7Yi8 g/PyKVzI0Mq+SaOMuCMyQZUVhAgbatzYsJYkDM+gGWmH4R2IigWZtOpWpB7HlzC9nWGTjgPAj54G ofzCMqbP/5+wqgwCsSYLpEi2KKJM+QUAAIQugUqdGmiCBUVX1BXJWW5nlzxnPFk44/TpQapo05Lx yCRawGBmloZZVQvkp7Jm1erdu8yKWxDtBnpde5JSP7xCAAjly7gxRZNCos0peSquRTJ0iwwLidix 58ZsI/+jpJMgH4/DDrTaJwpxgs+w1XrUiqZ0qj1M2VoodqDfYaexg6M1J7GkbaZiQhPtNwSOgJTM gQuXtWG6l27KuVpGjjvNGtpXylp/VX38Fuyku14m7NGcQAzgiTAFCaJVVPP4vW2jJVju3FQNnMGM FR4Y4QErz6Vi1xD35RdOedT9ASExOn1CEHdcqELIUmkQ4f/BhyCGGOJJ29wGGHP0OKiiMsPEVdEY qqxCC39JwSfijSCSKA8qQrSTTYMrBpkJAFbNGEaCKUE2zRAFgtCkkzk+k5BmKAoJzoRpjTNENxh+ UcuXn0DmAS9k8pLjlltOCYIq9KVoJTJYpoVeSl1akdtQNXIAojRCkPkhLfMgqZoRxVyV2JuI7rFY YWwdYEGdROBhopFEVCnEmEWYWWA/as7DXE/NWZroqGAUhMGAQihpJ1tFfmLjmZk+WR8S+62ZhKmf xUlqJdnUpcWLkVJaWwd7HsHnGWpqUysTvUUHAAG7BqIrCNMChZI5IQnLo61CrGZRMLIaCxAGqvW0 HzfJGsH/pq1OLXrPtNVSe0W85KXFAHLubWtnKngoxySfmQZLUX0Z5bEjUbOqqyCDQdIb7RECFvEl oUioImm3IBCLqbECS7Sbwd12Q44noCJpqJsPT+ewQ48aQdya/CI76RAWc5PEsSpFetaUB2cBZMrR WhUjvxSftJ58/ArQwJqt3JRxLxhfRGFGBOtsRQa7OQUq0IieMTTRakQKbMUWAyoABk5/kqy5q4WM EUJhJ0wHyvaszLUmS8UowMu1MVt2LW0XM+CyR6SRNEZyc0XrMFW+djepeZfdYd+qwkw04Cx5ZDDh wX76tttvEx7341vYjRYDRn+tWm+opEJc5ZaX6y/N7RCc/27CDayUbsnEsIniz2qZTrpOqqsy+baK H6H3cw5VrZKkh4d+8Fi9L/zjN8IP/4cBXhf/HHNsurpv0s8XlubWqdouffpXfDIM8A9qz0T24x9N 2m2+Ja88+QbNWBHV2kATrcLgFGjJT0WR0xuriJIG2NGMf/FAE+fc9j+QDdAL8DtgcLyWwEEZx3wC cWDryqUvWt0OdB1LoQT7xzANOmg7nBiCd4wzO6SRkFvKMp/tAsgF9HXrhodyIX4q0sFVWGoiOrwV BAN4oc8dDEW8y8MHLhi1xChGiNZ5VBEdVQQkoopsJKyhDhGnO5HtSFRF6110sDgdCKQuRlsJDQ1P 8kWFLf8RYurbXEI+J4QPTHFr6IkU6+jGxtisYmho8AhIaOgiMcauX0VY2hByF6izuG1JfQTBFJun rUFmsJB6OdWFYlSkVDEHLi6q3+oiqb6QgW4lc9skxIgIPRmhCY2g9AxdvsaWsDGykY4cms2qKLdX JguXgvQeMX2YS9mIcpSrsNByFFGZuGjLjkCk0EcmQMmD+fEDzPEjFYVBp2biB1paVB1X4oYiZkzM b3es1KnyWKJv2lNhltwb0czpIAUcx3WemMkvwtbIrtRvj5KgnvSYl0nNDAppjuSndbhHx7xZZZ6A CUgSKxrMmm2pZuhCGM2q91CJUQRSTHCXRKkyylJicjl4dExiHR0KwZKJLI2ZixyyVvqmpbTnpTC1 ZkRtCESWsE0eIJ2HNZnJU/NwTw3XWs5MCsecDW1heQKUpLIQKrGyNZVU2UARKS6KMN1UKTQdranO evZKDRHTD5/8qkYYJx+Y9uOLVfWfNeF5Q0qikFug8mol2iXXfAQBACH5BAUGACAALDEAAABJATwA AAb/QJBwSCwaj0hkpXLUOJ2b6CYp1FCv2Kx2y+16v+CweEymCkCNiXqI8Wa2HLGhTK/b7/i8fn9O r4VtWW9dHIUcHR1CU4FEFhZDFgAAe5SVlpeYmUgBZ0SMWBmDWoaHHh6FSY8TaGgRIJKasbKztLVE AH1rGJ9IolhRpB2mqSBqEw1CC51Ck7bOz9DRXrisW75YpMNGjkKrQsggAuJGzdLm5+i2AQtaoVpT RMKJ28V/4CDK4vr7ZwPp/wAD5ulzxd0oQ8KOqPKG5l44fVTKCZxIseIVTtWOXEMCLBiqRvXsNQCX j59JfdQsqlxZMWUxIhupBJsH0tiQkUUElDx5kqXP/5/oBlDzMyRmkY6FEm4zNiHCSJxDdupjl+yV RGZAs2qtNVTNG6NFZgISwo1hQ4cPTQ7RSW6r27eyCB7EYvYpWqnL2FFFUu4q3L+Axci9kq1DHEgv iTzNiXetzgYRjD0SsuxW4MuYuwxGgtBDkYWKoRJpTHkcTj82M6te7YUgLxCdaQ5h6upskQVS95oG xxvNKm8YJvhlTZz1ZiGdhQyyYPYsWnxqSy+wCyLysQWuXD0vMry4d60Qt3swjJi23efRSzdspea5 h0B/KH+fHzh8PNkgmBvTTn10+nzroYZMGiBsJE5k3EnSHX0MWiTXKYd1Y15/Oe2j22MDNjDdKthp Qf/gBLs01+CIKw22HG3OHYFbSVHtNpIaESgDhogLkngHBSDgN4aOz+CoBzsO6QdjikTotNOFfaAV I4FEeLYFMpMJUKONl5niZBhXZnLPfvw9xw4/RSY5knXHfMZFB7WtZRmV6WRphJtd8LiFj3R0QCd3 9ZDZFHXogZkMW3btx8YdAojIpjR3IpHoSnAOQQARrsAYgVOiFZlWZZ3YheB1TCY2hJWgWpnIdpaC ENyhqF4iZzjb8GmEXhA55hyZGqY5wSOh5mplhKwiUSgRhqYqLCXKbDjBAQfcdISRAP45HVS9OdSc KcLoWiRVTmlhQSeVDettGPj18QhR8WGaz143ndb/HpCTfQpqjohUq1gyUpF0xEidPDKlJYtm0S8V /4IRsBir5jjLwF8kCpkRIuoEpkPrCGFdA50E0u6nb2pD2Yq4tTbBIAoCtKgHCINBsr9lFCyNvHcE KeEq4jSwrZ+sSIlPGk5tSJYQoSrFs8b8rBgruvgk0S00cjbaqBBJY1lGltRWZKUdTApg6xriqAHm GvdQhVttj3CQ630ay6chbul9c6kAnEBUMS1ulnyjEXLKXSdrj9aW6Wwwi/PIPkxV0+HNTI8djykR Gtkp2jzpE2yvgDzuzNJUqFwE5ZhYLnBAB6SJDNEcCpAGREytco92aICqY9Te6NUxGrvgg9cZU2XR /4nkJNpdnOZYJFsdVGx181CRyJRexIDuXn6lOHs1/9IEjdMe9NE1F1jq7iDoTiXmXHTpidbjQP6y 6cuC4CTLFHfScceff50W0eJPx08ARvz6LRncz5cAWbXhFLPw4mOI8aTTFHfh51krkt1xpEMGioEI A9RTDZ3yd78uNMd/wArHdHyzkAE+ZAHg8wbzqnE2r4UPItiK3j5IZYRA7CswjdIecSiIBQhIaj1V qQewvFG61HxQDSwiHGQmwDEEMA9AK/IGC8OXBFyMozIhQ4cM8UBD8yWhirPA4he8Man1/I85RbiV kHoowtkU7TYkaV6xRHe2ajCxQhe53iuiYbelsf+sC1rEI5WU6L/bHQMcZiGjEvVRG6rgJIEWCtpI 9gKZCCbBLPRzTOxeiDFbUCBqRpjiEXh3hXlo8i2R6eI3PlcdACKmgz1Um8To1ZDXgeMMjdkHPhwB vyOQz2hneA0dhfBJLvQSC7/cym+GtJjg/WEVF0ulGpB1AH0MCFAQcUq2XgcdC50xC8xxpNpyibt0 3CmYeQAnJsT5yMDZhm8+zM/4SoesezyTKuN4HRETqbiisSNNvtLmvAp1qgr68wo26Q8g06lDQXKt foaUXaSihwZ0sXALkQRkP/9J0dlczDZZkxDD1mDQW+JDa0Bqn9ooRpqNUeyhW/yEPyrqTyF1CRn/ fkTmDjlq0IyAUIM4VNY1/2QSQJphNJGc12x0ydJvDbOLxfQpN9BJU0HaFIjwVJ/w4DfCIUQqn28s X1G3GsaAnsaiFohdSFJTU5hmjYh62ZjXZpfVnHhClkZIw5e4ytVVWKd/Pn3JRZFQU/l0Y0WLNFKY 6qfVDwjBsGsTBzPHRbGMmJGu3gpk/3a4M77Z0qlm/SuG0CWjb/SECB/4gFhBgNi1QCVN0lyb72AB 2VQ5wpyVkilibDlW45lVdK27VD6YZChkhHYXuwgtGlaYvsae52gCaBclW8sgJZqpq04ta1oIxLyp pAEsD0XLdialIVY0VqdYYS6bBJguHg7hMGMk3GNtzTld9QwRvMfz0PE6gU+Uhle8e4QtQDs6TPWW Brd+zSEVSnuvuC7sITDdwnLxuxrrqPIzB+AhfzvqGNwWN0yVcYgu0xcebskoAvo8woIZHJh2iehW ll3nhD24jDJ9Ca6kpUIDDsDhWE0qfN0FgyRWSuLvBNKU7RLSRpXp1AC7uCREgx/y4mupHIthxD3O jKE8yN/1pua7xUgfK3d6k2PwAydOUaGYowflKG8Fn499rA+r3Nf3ebkP1DRtmfaJU0vw2MysQbMp rTyZFRf5UpLTJ4hDXIYy4/kfQQAAIfkEBQYAIAAsMgAAAEcBPAAABv9AkHA4PBiJyKRyOaxUMlCN VLOpWqtMZCLL7Xq/4LB4TC6bz+j0MIBYLCJIi9wLzZw9Hg6nru77/4CBgoOES2xuEXBCc111jo+P QnoceJVZGCATQpqFnZ6foKGiIG1vi3R2YZN6lR5CqUkTE3ALo7a3uLm6IIemIIxLUGKrlF2ysyBu CEO1IAC70NHS01kEpIiNwmCrrpJImMezDQ3KCMvMAdTq6+y4pYkWwcPceEvhEeNu5edC6bztAAMK 7NMLTrwksLzQY3IskSJ95ZT48zewosWLS0rJ+0LMUixZDseR02duGT8k6ShiXMmy3YBrzYYk7EKv G5J7+PJBLGlOSM//AEB5BVXZsqjRXRpfzWTSEQ+HIeBAKmIGcUFJIiTXAA16tKvXUQVfKZzkkUjD RCJH7uxJqlTVBRS3/rP2ta7dP7040tMjJKrUqW/3wbQqJAInEBFUcr3LuLGZvFma2hxyNqfaqlfd KkOUKItcx6BDZxFwiAs3JZXTBrbKc20tN4inGiIqunZo0m1OEal586/l1azNuRYCG3GyN7M4ybbN vDbu4kNOg3iaxCHVwK13wtbXALHV7pQ7Z6LdvPzd0pLI1jMrFQnwnpqXNYtJ3BeeeLXwLaFrvv9R 9Kmsl0plgK3GU3y5FfcQEVBMVlgDnIDn2Ab+hVaaIg4OIV592GWn/8w1x5FC3ElLcNBMBG/YkRgo V7RIYSAvtpOhFxq4YgUIGnxhRY5MuOjjGS4KEaNnucFBXSa+XWegcCQliI1PpqSy1BAeJPbGOJt8 MqSWjG05hJdgdEAEmEmQCYYHPA4hJhfoUZbkcUsy+aGTbxxEIhgr0oIJl2tyqU6OZmaRZgdWXADC BmlmYWMVfTIhZqNdbLDemV5AV1hIIhnIGpyEFfcGYFNpciQXrgSVz2GFUBgoIKveoiqQMc7ox6th JPqFFFzkV5hxSmLmYTnz8XpcqKokFlc+QzQAwLL89UGrn9Q8G8aaWCABKRiBSutJhs8okSlwwWEW 0wIQyqKPmxnIiv+EK3BNJNcb5IKQwYowHhpKq7ZoK4aqVairhr6DXICrEgAsIAun4HZIn4YLZyIG XDANFRQCKHYC8CD4jnKxoF9ei2O9GaNhqIMn4mMYOQi7Ju58Jw5LKhOK9PRaLVvJhSzG9rK4zsYc H+qlrc7mrAQeHqtRi3IgNABHdyi+JacbbNQn7NFZJtGKg7AcyFY8NX9mMAgYCLAsAAakwTMaVwi5 s9BkVLtB0UG3CncYhgqB8nRQiHduynQGUDBncLQRwUGoUnl1JU/VwtZg5zbgrqkSJjPrGEAvMaOZ dfdRudq3cpH5mGjMfXYgBPgiE1bLaPKafJ0RFvWIDa97eFnXaL3/NzMIdA0UuQiAp+y/YnRwLeZf gjC3B1fISnS1ZTYvbYzM55z2F5+//KW/9rZavR8VJwFbzOcwTUs6CMzCFgaFG94KEQ81UxL5MP2T TBu6sxF5BN0CyTbwlCexeRk82tLouPCi7Y0hW/vrkR/AAxEkkMMcE1Cc5C4ludRZpRmzOxxWBuOd hfGkH/KDg+56Bxs7kCcMA3QUOzyGBwEmUAwXqIIBFbWvFzIBew+DkyJiRgT5sI8WIopgMjKowQq+ ZRExId85LJWM+iUtdgJomw11NK0kzM1Qc7MaEwCFBH3h0FVTJIRsIqIhEVXsaDi5m8MmCIKrsW+J q2HCOTTymdx1/81uDksfCsMYqT1qkQz/y4ILQ4bCFgGPkGogwA6l9rUezscw4ZgFEJOBjHPQrlfn os+mzLEYyQGlDeeoH5bMxkcC+jENWRRkF1/ooxvhIoWA0IRqFtad/KAokmdRI4M8orjc+KQk27FK AODFlk5qRUOiLMyUqIjIVeIilUgwFJia6YUgkZKaaZBk6wgDB04kpWo/jBxi+FGxIi2nLaUAZrJg Y8xl7K4f9YsXAw9YSlVSim5jUBfAsJmvegrCIe0T0XXMogS0gIdijiQMHpOgGYgsKCM0q5/Eete7 MsBSCV764hC4uEVVxiiL07TIxTRqBoBmikQj+UJOfEKLhsbEAv9ZMcntisMP3ZFCovCymS/FaUp+ 2jBD/vJpIIVALYwOzYq7uBiFrkVSJigyNpZ54J1kc7CCjoMfEcykQ4ODTktJUKBCqRk8tzIusdZy odUkJVKJcIEv1q2tNOpZ8UJqLXZsrBLVa2oXDKpLkIySMjDLRzoaAFONaAdFvkRnbuRDn5SIlSJl taka8ccse+pPFNC0LOi8oFeQ3cIwJj0pEjbkJlz6VY2aMKxwDNFVdRLhMykhjnckyhWqyU8XrvRC DFuV2yVQAVFn+K1P81WFoYYBApfi6/c0dM6qWvVuX4tPTKgDNcVyqBaOm6BcyBdR2galsRUK7ydA ax3c0eec4Kz/zs0M1gC3sPGXH3QtzaQW1tiOlazkuGPsXiLe/gYCoAUiUfogGVhdRmC17/WOSZQY osGMw4laiYnj7hg5Pfr3wmd404ioWlDnqvduyzhwgoRj0HP5wyS/TIeKHHvHO92xibuyMIZnDIay QXVDCg3HEgi845uFmElyGmPufknfNcDTYbkrxYTFyjuhxJjGUCaDJgD8ra+h1ziJOEaPQRw4l5pu cXMszuN+0UM22NFmGnKnPwwS5TZ/gQC+0duJPJyJqUDSwmgRaMw8FdP3qQQ6XPmAoAcNY6H0jhzI IIUI/QGesUXRzZAuKJVHQqw9IUmbWcbzcniIO/huRyVqbtgH/9CxGICq5MBymSQIHh3pSDMgzg/p piwszb7k0llDB0XdPtS5wyEbmU2LCXOwGOtkIQDAH6xudaQBnBNTJIcLAL11GRU6IpMwqYx3+gZK 0kGu9tbsU90zjh09+Rllm5vZySCWN7LAY6uCNYIIjoCKvuqFCSfjqrXd4Hbq67etHNvcrVZOaHeI 513dJLDUNqLBk1Cz5bTr3vd9TQXlo2bv/hvgkIYDldmn6VoLS9LdWaLkus1QX25F3k3kNngmpjjE KhrV3q3Z2DAO6SmbNAuHIS2eripb3Fl7YQ8v9sq5MhUS3zTmtKX5sgFaRoaAxB4FFjl83Tvqoctv 6Ny+lOKagWp0i4+Nv0q/MBxU1BkVcUHG6R0tz9mY2M4sZs1GPkciXOeTx3a9fl8P+4UZcDqEEPTv HZZxTu6UWBKFGCUT5Hp9tXJ3ieZP71F+CnhgYWfA7pjdWJojVhLeO/3obnVObrzXjz22x0NeNEEA ACH5BAUGACAALDEAAABKATwAAAb/QJBwKDQIhpAkcclsMjPQKFS4cW4yTuExy+16v+CweEwum8/o tHoYaVosXKyYQ697PFw4iJMJrP+AgYKDhIWGQgB5b01RY3RdckOLIHqHlpeYmZqbRIlsb6CVRFOH kyAREQtCDX6crq+wsbEEnkIRoYyRYXV0eFmVqA1CCMQBfq0GssrLzM1pt6ajZBxNvkTAbSCqRAjG AQjO4eLjzrVxjmOo2QvsC8Tv3sbg5PT19obm2aO6XY9MHtSEYAvWoJ27d8XifWt1r6HDh2AG1EK1 b9e5gREaFGyHEJ5ChRBDihxJhCI/LwGZBMSo0SC7jh0/xgNBgKTNm+RQnczCi4O1/2u21LV0CRMh kQAAkiIyhrOpU1jmLDrhJ3SowaLvhs0DkbSrt6dgw1qaOKEfrzt3JLEhuNHlQZhDiHUBwFSs3btp BEw882bCBHUZ217FGndIA3Vz8SpeHMbTAn1LzqJN6RewVaKEQWw1CFjfNsagQ395bKaq4MFwNQ9h t/azNCZRRctefEuI5LRDKrN1+7JoXAEIWLNZ0iD4kJ2zkzMm/cXyZY6ZtW5bcDiV3CV+sunZqrz7 XeZEqOlxfhq6b9VCPq8T3sSYsM+uvb/CLf+Sad5vUw9L306bYRBYWIBcAK4hV18mP5FhTYKwoEWf Ja5ho9FzvWWGkGsZATUEg/+ld//UgRBxKIuIaZBY0gQSTsgbVtxxV9J7ZyAgDCUghvhUggyK+M1a p+y2YnSazYPhKmewUtdmNTJmoiY4/sNFMM6xFxeL+zXRxow0ohGPKghAluRDSy4RpoJkEpEjF8L4 +KN+76gSn2r6eBmGTPsZ+GUzY1YzSJ5miunkEN+w44eLTVCJ3mrUcYOlnGAwJARIHj56Zz18ClGp IU2CsCCgbS7hzqFadTSlkP0tIcoY3WQ1o6OSfgpCWZPeyEymfYJwQHCqpELRKatspd9qq6Hyphk7 MrHAqUzMYwGhsYp0qSwKKMAOlmwclF5qw4IwY7ZkfGPUMHU9+hGXjDLpxLPOoCv/iIjqYjJjBLCq 42qQ3xbkKWTZwCpGBKkSutVMXByBBbeYlnlIuxs+2KwQBAzAq2aHwYEYMaiIuso2LgqDrBcZsELM S9xkpZkxGHfCDcEHL6ynOAgTcYBAW7WRAUX+dtnjRn5QS2xW2YDTjbcIzYQFq1PaMsQWKbvS8hlL 38WAtqdwtIR1wUXg7VoZ9TYjs138ehTQWYXLbCv/IqhyiRA9LcxGJWFRcTePGtdjMOCmR7SfxV0H Kq9WG6oQd3SR7Nrde4rBZ5hN05M4Jyr2BiBFrVgNNdYbwa0t4deKqvfeLcrDeTxKabNAANkwpEAh laaOxuLzmb3GlY13s00bC0GN/69Qdb8dXpXauIjrvNzI9NGptajSysbrGq78OKxn0bzzf8DeEqDv WqtNNp2tUhDcPQMYZKSubs6F8MfMGVdXhDxvqRfq4ynSX4EJFvPtQQXlmeX8yiMk9thZzAT5knJC bKZTMKWBpn0rSwME2MI2EDAkThaI03AI4o7IiQEmBiHQ6BKSLC94wkUoY9rZVkeS+A1laqlIFAp3 tSvjyWgYpXJCUTjih0SRj05tyEbgBoWAU9XkCw5ykJ9GaAYEGuIwE7JKN941oVNlryqfAoe+ljAP alluVIS6YXbGhx47iXANhwvN84yYAO0lUUoRDIwQpoiYklyLZL3DFRHs5cDvGf+KGjfkWifC9bjY EPGPa0liW66Tvdzopo0Pq6CjvsU5erUJZKX72UcCuIREhO4zMxuCwwDJSSI1Lj6AQeHcWLgePgKr a0RohzdUqUVvxMYcpDsF5jq5MFh9cl6IzBLfOtNGQRHqKoEqjANF1i/VjO6GHdojU4xROlp2MkOC 3EaaUOEXXbQxlEYTHVMg4xqdSZIwg1NI4OqYBYaEa5bO/NKVtHXGqTkBm/CEzDvKhZ2QGeVntvgI PY/CGoWsKp2cjCYT2lAWa14TniGzhciSxaJ5CA8cH/CCcfglLm8IYwKtQBpA77ROdlqFf7q0HykP 2pJ58utjb6rZdf7WhIg6kCH/XDIWwPa50QPVxowD1U5JGFXIYFToMI88CNhwJUlvobOD0nxUQXRG tpqebUbtpFEbTAE/XtavkHEEx0mZJTc4xONnIeSdo6azUnlgNHROTVICIHNGFQpED2/AKtZIiSXx 6dF4CyGQqTAALLpEijjCkB0dh7mArnRFo2n1DgPWmUQiPWyFVq2fSEv6sZN5sxiSzMIxW/EZpnQj I6mqWyUNmxTEJrY7ehBoF3j5xDjhDlwl0+VQuaMzQF2rCcLgbEVJOwTS+vG03YkmNNwJ2dbmcG6U 9ZVxZks0pr6xLq4hhkZ6i1ZEIOK3wK3P2jSCPX1RRBSspciuArm96+QnJvoQmp6bvtolNTYBu1zx LXyzC5psJHG8RIBflsKLmHiuQ2TA29tLvWEcRcrjMYFlCDiqOxdL0vdATKyOlXq0U/6OEnv/Na+Q 2kPg59ZQFavyHFe+0hjDPlg+tc3mVcfLX/FaNTBvsRt/ghauzSr4pK3MsTGUYuITKwcCwoBCSm46 t7nFq8UtFt1Lo1asAcP0bnnT8Q3lS+X5+vghQQAAIfkEBQYAIAAsLQAAAIcAPAAABv/AgnAoNAgO SIiywmw6n9BoZkqdajSbrHabiVY0FcEgQSybz+i0el02BBCLRSQysdjvdox+z6/6/1QcgoMehR6C VHsWGBkcGQECBmyTlJVrBgBwcnR4d3x7gKF+g4KGhRwbU593dRkTAACSlrO0bJiac52Ln4yivo2k po4ZfHgTc3ENDQGwsrXP0AUEmXG5nry/oqQcwqqKdscRygsI5QEBC8yx0eyz07gR15/ZgNvdxRYT 4eJx5OUI594wE9Cu4KR31eLx6kUvkL1T3jCAmzOnQT9//wKeAwhggMGPaBBu2gWq4ZRt3Aw50sOK ojiL/f5l1CiQmTOQOAdQ29THJLD/YBCJtaQ4LqZMczRpAiCIs6lOeIwY0nt4aOXQijAvHj2aVCMA Ak1z7pzjk+ohYhLzuSyqdeu/mOoAnJM7MCzIp9UmNKQ6LK0+omyNutVUrh+sw17B2i2IV45eX2at 5tunLOtFjEfj/ONkJ0JcWHOZLmYnYKwFbUDP+t338rLmwUaTUVyUwUJpxOpujq5VGtfpP6lVT15r ua3b15r6uYwQdcFhuh13RxPwptpvh6UgrgZcXHBmjJcbIMtLZ0qE54elQ6Pu+yQhlUL/Yu2O/Ds5 AcllRyDXwEIDOOFMMcFnAJChHi3sVYNBapKxVplrmNn3Fkzi7VcOcxkUYgE6FZ2G/wECzyl2oCUJ ygHMKY5MxB2EEcqE3EUVTtDPBAwZ8kgA4i2gFwbOHabbiGskKF6Gwqk1H4uDJfeWVjry5+FpKamU jhwmZuCZj+pRsMUWaJQYQSO1DfdSYN5tVd9FFZEjx5NEmmLKMlQ2wMiAWO62gZuGdFmdeHWIWRl9 SQq2QFbxiAMgS6fhqahnCIxzmm11LnZnBxRUaika1Q2ay4oQBvoiTHMcY1F/etAYpaJuLnOOMgjs 2OM6knqwwSSYbFIhVkh6OuGooYK6SD4LooonB57RNCgCX2LQwGEiNnXnrGkkQIBOsPR3ZK5mfpqM PjLCwRwGx7QprI3pdMVho+ap0/8sSM+mQUCmzLQ6AX31fbfrtsc4KVF54wpjQbmadIVsHHOq45Gz sqLhxlsV0cFffi0qWZhlFvCzpkSm9mtjBABNGIe5FiFw2gS3CaAATu2ecYAm+TYsjn8Su9jPnsrt t22piWp81jKw2VEuTazqZQGIzbCbcBkKKJAMmFYiU9i/x13ETD8VqqkQsKeOy8G/b9h7zgLKmnts sq/+CM2dihpAwKCM0NG2041OYKbFIFbntBw4i9uvlR3D9nFA5HQ1qAANEPPqumejOu2QHIt3GkX+ zHFUA6J+XM4x5ciJtc47d11f14UFjo4/Xm30H9gYnAfLweykTAQBB/Q3tHJv/3f/+QL4XRgOTG9Q rmbOOm+dDsMWir6VRnoVS1Oj5bStjmiJQ0sEA7GnHhPeqVvorefy0R23mpy70mIyEs0M+ltf2wFQ VyGP/HzrR08fu39tfVkxxwDtV133rQHkOzp6c1MGbKeky0RgA4zy2/LWxwzA4U4vdFpKNFw3BLXF 40GvSV4EEuSZQXGLMppBx7zeEEAO8MhME9MMlbhSEzisz4UMVMfX0mG/552sFhQUQgISQIc/hRB1 4hAIP+jALeIEbhPlaJPwlgTDJZFuhUgxV0AWoTy6oGMZ9ivZDWeRQyEooIcYDJyc8vW0NbGGDv3j EP6St6S7RehFC1iERaTIwDhu/0hwy5DThw5jIEt0UQi7C0w5qGizOOYiHPzjR8cktxEXykEZhQyc ffCWgZ8lBQ5SlGHv4KCHsnExfmWAwHyy4r99+SoeailiICXpxvDUpkyh+5jlYqiRKBprP3RhHuo8 WYk/SmOUpBRZ9sjXJ/51L2S96xaLtOc3SR4rk0lZk/6saDs5MquXqCqCeP5EShyBa0yeMBJFKIPM 72kimINSkyTfIjOfQZND9AMZAgTwuGtOAm140iEYfajCzryERjRSERGLqMivdUti6Qwi6QK1IAxk Eg4Vs2TpcPRAK9mTHaIcE1sulD2KSARjiSQoMkVIQCYuSEbrlJnVVEXLgGCyK/9yAc3oBJA8g7XD AD0cE5P25VFEhWo5x/ybjk7nGubIzVN/G51EMymXdM5lVTRMnU2joQD5hNEfNBrnLlR0xuXwDkD4 u0zHoPjC0PWNP0vFox5U1cBVncOoU4UGA0SlUZg0qqP6QIs4jWnVvyErrK/RVFEYOBgASjUpuQwA Bj7AI/b9DK6riwZO/VNXzfTnGPogiTiJ6JJjhuxCgI3llwYUQhS+9bAaYc5YByU40QVkjHGtRR2A eZHZxoNG8QHqGa362b86kXZJCp25RPaB4n6oa8vTFLJoCVtYQM8dOdWocu7Xp9zq9rr9A+1vYdlI 4dZyscUN7wckCof/iOo/+nv/beoO89xKfPF+lZUmZ6yL3XHuDjnicaI5vObSOoJ3D+FtrOlsVSxe xVC17H3GXOc1Sutg1g70xW5Xx/GP/BbmOMypWC2/9l8AM5atjfoPjpJj14BtJILOrQUPO8rPy843 TMvp7G5XWeGDymxHFtoIhwO8COOmo6kj/Voa00nYVyWYFgy4YGVl57YFmRC+MebsQI34FhtrihjM rAmOxBvgnxFZI4Ez1J5aip4jW6KqauHmmiqGW7R8M8rjDBX/KAyQJj0touezZQPEK+ArutbPczRr QNAzaPSwrhI4TZ2aUem22jS5q0CNMznBc1DWHg9sbC1cn7+8Ec0wk1VzkemgwENtaCRndZuQpCJu s1eHN8MZjQPlLaUjZo4IGFdsc+wvVgoj5raaq8zPOfQkvrjWysxBDwohBiIXAenOyngts84MJz9M Xk53WhwcG7Mm3ynDUlvCAHKyEiSTlezULdvVcJ4xUaKdH2RcMkdFfqRrzWFFbhe6zMJmAwPCjZZG HOM3rJ4NuqMM6fPOOlOYcWmOgEYO/Nmb26ABdr7XAIH+uEdZ8VBFnEM18FdH2a4b0R9harnwaNru 4VIEtsqjM4QgAAAh+QQFBgAgACwpAAAAhwA8AAAG/8CCcCg0CA5IiLLCbDqf0GhmSp1qNJusdpuJ VjQVwSBBLJvP6LR6XTYEEItFJDKx2O92jH7Pr/r/VByCgx6FHoJUexYYGRwZAQIGbJOUlWsGAHBy dHh3fHuAoX6DgoaFHBtTn3d1GRMAAJKWs7RsmJpznYufjKK+jaSmjhl8eBNzcQ0NAbCytc/QBQSZ cbmevL+ipBzCqop2xxHKCwjlAQELzLHR7LPTuBHXn9mA293FFhPh4nHk5Qjn3jAT0K7gpHfV4vHq RS+QvVPeMICbM6dBP3//Ap4DCGCAwY9oEG7aBarhlG3cDDnSw4qiOIv9/mXUKJCZM5A4B1Db1Mck sP9gEIm1pDgupkxzNGkCIIizqU54jBjSe3ho5dCKMC8ePZpUIwACTXPunOOT6iFiEvO5LKp167+Y 6gCckzswLMin1SY0pDosrT6ibI261VSuH6zDXsHaLYhXjl5fZq3m26cs60WMR+P842QnQlxYc5ku ZidgrAVtQM/63ffysubBRpNRXJTBQmnE6m6OrlUa1+k/qVVPXmu5rdvXmvq5jBB1wWG6HXdHE/Cm 2m+HpSCuBlxccGaMlxsgy0tnSoTnh6VDo+77JCGVQv9i7Y78OzkByWVHINfAQgM44UwxwWcAkKEe LexVg0FqkrFWmWuY2fcWTOLtVw5zGRRiAToVnYb/AQLPKXagJQnKAcwpjkzEHYQRyoTcRRVO0M8E DBnySADiLaAXBs4dptuIayQoXobCqTUfi4Ml95ZWOvLn4WkpqZSOHCZm4JmPQBZAwRZolBhBI7UN 91Jg3m1V30UVkSPHk0SaYsoyVDbAyIBYjriBKV1WJ14dYlZGX5KCLZBVPOIAyNJpbiZaiGcIjHOa bXWqd2cHFFCARnWC5rIihIC+CNMcx1jUnx40Rqmom8ucowwCO/a4jqQebJAGJptUiBWSnU4oKqif LpLPgqcmyoFnNAmKwJcYNHCYiKPdKWsZCRCgEyz9HYmrmZ4mo4+McDCHwTFtBmtjOl1x2Kh56jBr /5ezZRCAKTOsTkBffd/pqu0xTkpUnrjCWECuJl0dG8ec6njUbKxEuPFWRXTwl1+LShZmmQX8rClR qfzaGAFAE8ZRrkUInDbBbQIosBi7QxygCb4Mi+NfxC72o6dy+2lLKqIZn7UMbHaQS9OqelkAYjPr IlyAAgokA6aVyBTm73EXMdNPhWoq9Kup4nLg7xv1nrNAsuUai6yrPxZ0pyEGECAoI3Sw3XSjE5hZ MYjVNS3HzeHyayXHsHkcEDldCSpAA8S4qq7Zpkg75MbinUaRP3Mc1UCoHpdzTDlyXp2zzlzXx3Vh gKPjj1cb/fc1BufBYvBHKBNwQH9CK+f2f5YvgP/fheHA9MbkauKcs9bpLGxh6FtppBexNDVaDtvq iIb4swy8jnpMd6NuYbedyzc33Gpu7kqLyUgk8+dveW0HQF2BLHLzrBsdfX+WXVhb5ADtV532rQHE Ozp5u5kB7Uq6TAQ2wKi+JQ99zPib7fRCp6UYBGVpi8eDXnO8CCTIM4LaFmU0gw55vaF/HOCRmSSm GSpxpSZwQF8KEagOr6XjSxuCRcnagbIEJIAOfuLg6cQhEH7QYVvEAdwmytEm4C1phUsanQmRUq6A LAJ5dEHHMmBIMpNFA2VHw+EEAScnfDltTayhQ/44tDFW7Q10dovQixawCIs0EYFs3FDgliGnDx3/ xkDPwGIBcheYcjyxZmzMRTjwxw+ORW4jKZSDMgAJOPvcLQM+SwocmtjC3cFBD2SDhh4hMJ+s6E9f vYqHWoDIx0amMTy1KRPoPFY5FmqEicXaD12Ud7pM1kKPBOikJ0NmvfDxCX/aA9nuuMWi6/Wtkcai ZFLWZL8o0q6Ny7olngpgAPH4yZM4+taYPGEkilBGmNzTxC4FpaZGviVmPVMmh/wTSY38RwCOi+Ys zlYIIdxQXtekXmdeQiMaqeiHQCyk17gVMXLycHSAWhAGKAkHirUzIHSxiACOJ092cHJMbLmQ9Sgi kYsRMqDC7CAAj7ggGZkzZlVLlSsDMsmuyAU0/6KbqJUK1g4D4HBMTNIXRw8FquUE0286Mp1rmBO3 TvlNdA9tolzIORdVvRB1NI2GAuSzRX/QyJu7UFEYl6M7AJXxMhxbogpBxzf+JHWZdUxVAlV1DqJG FRoMCBVGYdKojeoDLd0EJlX9dqyvviZTRUHgYPgH1aTMMgAY+ACP0uczt6ouGjb1z1w1059j6IMk 3fyhS4IJsgv5dZVfGhAHR9jWwmqEOWEVVOBCF5AuvrUWddDlRWIbDxrFx6dhpGpn+5pE2SUJdOUK 2QeG+yGuJS9Tx3Kla2UIjVzKq5PKoRhnbovb6ubPs71VJSKB+8rEDve7H2gnHP4Tqv/Yr7WoO/+M 8yyhAELJlpnTvdhyQJXb3CFHPEk0R9dYCkfv7uG7iy1drYi1KxaiVr3PiOtzMWody9qBuvOVz1bH 8Q/8FuY4zKHYK73m3/8qVq2N+g+OkkNXgG2kgcylxQ03mkNBjfLBYZqvN+t7qwoTNGY7stBGOAzg RRA3HUsNqdfGSE7BugrBtGCABCcLu7YtKITSlbFmARrEt9w4U8QwZk1wBF4A+6zIGgFcofS0UvQg mb11KO+DRNm2iGzVp/R1UGc76I842q94rQVvgKXIWj67kawQfU6gn7O6StgUdflks20pRiNtSrmn Pf0meAiq2uJ9Ta2E2zOYN6IZY65qLjCFKKi80VNoSsQV0WNSSJutVwdHP3qQGqxxYW5cvAgQN2xu 5C9WCjPmtZbLzISeRXv14Kc56EEhxBjkIt682c06aNJqvOSHxbtpTotjY2SupDpbSOpZVJNti0QW slGnbFdLmcZpsnKdafbQRumY04pkrTmiuO1Bd9sSDJCTNxpxjN+wejbmlvGbywttTGGGpTn6GTnK WO9tgwbYpWYDBPrjnmTFQxXe9GbAHy1jum7kzhxE+HmLRbuGKxXYKC90EAAAIfkEBQYAIAAsJQAA AIcAPAAABv/AgnAoNAgOSIiywmw6n9BoZkqdajSbrHabiVY0FcEgQSybz+i0el02BBCLRSQysdjv dox+z6/6/1QcgoMehR6CVHsWGBkcGQECBmyTlJVrBgBwcnR4d3x7gKF+g4KGhRwbU593dRkTAACS lrO0bJiac52Ln4yivo2kpo4ZfHgTc3ENDQGwsrXP0AUEmXG5nry/oqQcwqqKdscRygsI5QEBC8yx 0eyz07gR15/ZgNvdxRYT4eJx5OUI594wE9Cu4KR31eLx6kUvkL1T3jCAmzOnQT9//wKeAwhggMGP aBBu2gWq4ZRt3Aw50sOKojiL/f5l1CiQmTOQOAdQ29THJLD/YBCJtaQ4LqZMczRpAiCIs6lOeIwY 0nt4aOXQijAvHj2aVCMAAk1z7pzjk+ohYhLzuSyqdeu/mOoAnJM7MCzIp9UmNKQ6LK0+omyNutVU rh+sw17B2i2IV45eX2at5tunLOtFjEfj/ONkJ0JcWHOZLmYnYKwFbUDP+t338rLmwUaTUVyUwUJp xOpujq5VGtfpP6lVT15rua3b15r6uYwQdcFhuh13RxPwptpvh6UgrgZcXHBmjJcbIMtLZ0qE54el Q6Pu+yQhlUL/Yu2O/Ds5AcllRyDXwEIDOOFMMcFnAJChHi3sVYNBapKxVplrmNn3Fkzi7VcOcxkU YgE6FZ2G/wECzyl2oCUJygHMKY5MxB2EEcqE3EUVTtDPBAwZ8kgA4i2gFwbOHabbiGskKF6Gwqk1 H4uDJfeWVjry5+FpKamUjhwmZuCZj0CWQQEaJUbQSG3DvRSYd1vVd1FF5MjxJJGmmLIMlQ0wMiCW WQqxAZfViVdHmJXRl6RgC2QVjzgAsnRam4gW4hkC45xmG51Z3nlGdYHmsiKEf74I0xzHWNSfHjRG mWiby5yjDAI79rhOpGdgskmFWCGZ6YSecrrpIvksOCqiHHhGU6AIeIlBA4eJeKCkQiRAgE6w9Hek rGVqmow+MsLBHAbHsLmrjel0xSGj5qljrHTIEkApM6hOQP9ffd/ROu0xTkpU3rbCWNCtJl0FG4ec 6nh0bBFvFFYRHfzl16KShVlmAT9qShQqvTZGANCEcXhrEQKnTXCbAAqoJ+kBmsA7sDj+IexiP3kq t9+0oB4K8VnLwGZHtzSdqpcFIDZDrgIKJPOllcgUZu9xFzHTT4VpKpSrqNtyYG/AJwOEzrDeAius qj/itIEBBATKCB1fB83oBGUyDGJ1QcvRsrb0WjkxbBUHRE5XgQrQADGqjqv1skNKLN5pFPkzx1EN dFpxOceUE+fSL8MccH1QE3bOa15t9N8CepwHi79hbUDAAf3hrFzY/yG+AH4XhgPTG4Wn6fLLTqfz VtpSb6X/kV6+0sRoOV+rI5rWDICOwcpJZ26htY/LZ/bYaTbuSovJSIRy5IVNbofUSV2cse+dB9+f ZRfWNjhA+1WnfGsAtY4O221mULqSl0WwwaJw6449XeicrtecSzW1NQHxeNBrcBeBBHkmUNSijGbQ oa43sI8DPCpTwjRDJa7UBA6184dX6FIxL20IFhwDyQYSkAA69GmBmBtezALADzpQizhz20Q52BS7 JWHwZBqsIFK8FZBF5A5/gWJhbTbWMYPcSQEmFODc4gQvoamJNXRAH4ckhiq3FWYTaYrQixawCIvw EHtc3BDdlhGnDx3GQO2QlOoCUw4fEm9h8QjH+fgxscFt/wSDclAG8eZmH7VlgGZJgQMP1WE5OOgB awWRFATmk5X0yetW8VDLC9fIx7S55m72YtcVK3Y47Nmvavuhy+5SiEh2SAqAYmJLG4e3MiaCgzXK uxjrqsWi48GNj8AaZFLUVD78la6LxTJlEcTTp0biCFti8oSRKEIZWTJPE42Ew8UW6KKTzUyXHPIP IDXyHwEALpjQkFQJ1VXMmIQRKzSikYpc+EI6Tq5aCAtUHtFhjj8tCAODhMPCthkQulhEALgDJzsW mcpoMmc5EnHYHNspSwa+z4YLkhEfJTTPmgSSn3MhZP4AaqV+tcMAJhQTk+RFkW9wajmxjJuOLuca 5pAtU/9xyx9GvSUXeWYUR+k4qEejoQD5KNEfNGLmLlQExeWsDkBUvMzEdFi7K76NPzP9VRlLxYyA lMqlO4UGAzpVUM3EiZk7chhYXcLQuAUrqa+pVFGwN5j1Da8rogwABj7Ao6548RxY3Vw0QOqfrjrp GPogyTJdSNZmYmR8aa2GK/L3tmri9a00Yc5Sg7jLuXETW1mtRR0YaZnNxjEqgyVsYWO1GSoaTG1J uqK3MPaB1n4oYLqrVLA8eUz+/c4dIU2lcuC4p/gsR7RjRd+FTIspC55Md3NtrXI/sE1pouol+rqs 5vpXCyTC0a+D4oxvf7tQ1SFHPEvSYLs0skPMuVYPyq3/q+Ve5ataeVKyh7ltJbaqLkZaB7B22C53 5fjbcfwDvIU5DnMWRt7JJZcPrqUqo/6Do+TARLUb4R8Ia1FCVuo2UJLML5h+G9zg+ldx8DzZjiy0 EQOndxGuTUdNGzo5KcqTraqKby0YEMCuhg5sC4LgdTksn3aStjAhrhQxbGnRBiw3vTR7sUbmRqg8 0ZZAMp5FT9VSzkiCLSJFRSmnzvdhBvrjnLKzoKmWq150sNjMNnVqP5+z5udwrhIgVeEJrUwj8dEI mRxmpp4N+xZ4BtF2mKPq3cqs5I1oxpanmgtoKgfl6MxiqyoUk0KuzMo64DnPUWSnTy8G5IOZIwKu rdpdo++IFYExuKo8RA963jwJJOqhT3PIHG3wbOksk3W0RAFPiANs3mE1t9CGFofEnKxRbBJy1bMw QJyspEdhKWTIclyErfWMazp2epNYDGSOYJxHy8IWf8ZuM7ItwYBlo6URx/hNpWdz6TxnuVOcBpDs vBMQRpWPm+SgYriNDRpVO7oSEOiPe4YVD1VQG2zTxnSuLRtdydU7R2Pc4b6T4u+K/7sAQQAAIfkE BQYAIAAsIQAAAIcAPAAABv/AgnAoNAgOSIiywmw6n9BoZkqdajSbrHabiVY0FcEgQSybz+i0el02 BBCLRSQysdjvdox+z6/6/1QcgoMehR6CVHsWGBkcGQECBmyTlJVrBgBwcnR4d3x7gKF+g4KGhRwb U593dRkTAACSlrO0bJiac52Ln4yivo2kpo4ZfHgTc3ENDQGwsrXP0AUEmXG5nry/oqQcwqqKdscR ygsI5QEBC8yx0eyz07gR15/ZgNvdxRYT4eJx5OUI594wE9Cu4KR31eLx6kUvkL1T3jCAmzOnQT9/ /wKeAwhggMGPaBBu2gWq4ZRt3Aw50sOKojiL/f5l1CiQmTOQOAdQ29THJLD/YBCJtaQ4LqZMczRp AiCIs6lOeIwY0nt4aOXQijAvHj2aVCMAAk1z7pzjk+ohYhLzuSyqdeu/mOoAnJM7MCzIp9UmNKQ6 LK0+omyNutVUrh+sw17B2i2IV45eX2at5tunLOtFjEfj/ONkJ0JcWHOZLmYnYKwFbUDP+t338rLm wUaTUVyUwUJpxOpujq5VGtfpP6lVT15rua3b15r6uYwQdcFhuh13RxPwptpvh6UgrgZcXHBmjJcb IMtLZ0qE54elQ6Pu+yQhlUL/Yu2O/Ds5AcllRyDXwEIDOOFMMcFnAJChHi3sVYNBapKxVplrmNn3 Fkzi7VcOcxkUYgE6FZ2G/wECzyl2oCUJygHMKY5MxB2EEcqE3EUVTtDPBAwZ8kgA4i2gFwbOHabb iGskKF6Gwqk1H4uDJfeWVjry5+FpKamUjhwmZuCZj0BSUmIEjdQ23EuBebdVfRdVRI4cTxJpiinL UNkAIwNimWWQ1YlXx5eV0ZekYAtkFY84ALJ02pqEFuIZAuOcZpucc6JRXZ+5rAjhni/CNMcxFvWn B41RFrrmMucog8COPa7TqBmYbFIhVkhSOmGml1q6SD4LekooB57R1CcCXGLQwGEiNpoAATrB0t+R rY5ZaTL6yAgHcxgco6atNqbTFYeImqdOsEAS8Cgzo05AX33fvcrsMU5KVP8etcJYYK0mXfEaB5zq eJSlG29VRAd/+bWoZGGWWcAPmhJxyq6NEQA0YRzXWoTAaRPcJoACQB6gCbr6iuPfvy72U6dy+zG7 6aAHn7UMbHZYS5OoelkAYjPqKaBAMl1aiUxh7h53ETP9VHimQrR2Si0H7r5R7jkL+Hrtrr2W+mNT BhDQJyN0UH0zohOMOTCI1d0sx8jTsmulwrAxHBA5XfUpQAPElMptU8QOmbB4p1HkzxxHNYApw+Uc U86bQZdsstH1GV0Y2uj449VG/yWNwXmw2GsXAQf057JyVv/X9wL4XRgOTG/ofSbJJROdTr4WIr6V RnrlShOi5VCtjmhNMVD/+eMxff24hc8SLt/WWJ8puCstJiORx4a/hbQdAHXlMMSz22V7f5ZdWBve AO1X3e+tASQ6OmGvmYHmSl4WwQaHlv1688yczblecS4VVtTxPPha6xEk6FmfzVKmGTriekP4OMCj MQFMM1TiSk3g0DwGsk8dSEsHlzYEi4nhJAEJoEOe/uc4cQiEH3RoFnHQtolyqMl0S3LgkhSXQKRc KyCLcB1d0LGMCUqMYiBRgAbth7Y3oQtnaGINHbrHoYSNamyH81qEXrSARVjkhexr4obStow3fegw BvrI5wJTjhiGrIm5CAf3+KEwvG2EgXJQxhfRZp+vZUBlSYHDCyEYOjjo/8FpIIHAfLLiPXXJKh5q EeEW2ajE8NRGTIdjGN8eqBEX6mo/dIGd4/BoEALskY8P253x7sS93zksdM5iEe/KxsZdzTEpaNLe DDXnRGAZxADiyRMfcRQtMHnCSBShzCeDpwlM9ulMbHxLx1J2Sg75B44a+Y8A6ubKdmRQXLLMXWde QiMaqSiEIiQj0pz1r196UHF7WhAG5ggHgSEzIHSxiABa10x26BFMbLnQ7igikYKNMZufBCD5Urgg GQWzYz8DFSMDIseuyAU0iVunlerVDgNoEExMUhc9BXWp5XjSbDpqnGuYkzVKmS1x53yhXH45l1BJ 8HEMjYYC5MNDf9Aol/+7UJEQlwM6ABnxMgprYQMPRzb+hBSVVgRV+0J1Do6mFBoMwBQ8YYKoeeoD LbjsJEvNxqubvgZSRWHfYMCH0qREMgAY+ACPnKcyo0YuGg71z1I1059j6IMkuAyhSzzpsAtZNZFc GtD/DFjUrmqEOTntU9oQFxAfHrUWdbjkRRIbDxrFx6JCZGldq7pCzCXpcNd62Ac2+yGjvQ5SvGKk YSsIDUuKa4/KERhnHgvZ1nbPrpVF5Bkx28iwbva2H0AmHP6Dqf9or7CPOwztLKFD1a41last2HIu FdnPIUc8KzTH0QgaRdvu4bZjZZyqcgWrBwJWuM9I6mnhaR232oG1y5X/z0zH8Q/oFuY4zBFYI5Fm 3euKVaiI+g+OksNUeG0kfqSlRQbnucE+BfK8XlpuLpvLqvZys2M7stBG6IvdRXA2HSPNJ9KI+Eut lgq8tGBA/dZquaotiIDGVbB6ucfewjwYUsQYZU1whFvsqqzDGkEboOo0UPSAmLh16O2DAFm1iMzU osx1UF0B6A8pam91hcVtdmlIWCo/kafofE6WnyO5Sjj0cdEksmMFRqNaKjiXaNYleLgp2NUlTahs mzKON6KZUYpqLghFJ57R02VKJBXMYFJIkXdXBzOfeYjYlOya/WWOCHB2aU+kLlYKs+OhXsvHXJ6F DvWQpznoQSHEEOMihY4817k6aNGZseN9dTtnOosjYTymYzEhyOdZwJJqauwVqB8nakOfmcFmegub QXZOREmYzmkkrDlmOOst19oSDHiTNxpxjN8Qeja+VrG2Wwyg03mHoDlaGTmM2OxZgwbTfWYDBPrj Hl/FQxVovlS2D61gpm7kyf8D9291pblyixTTAO9yEAAAIfkEBQYAIAAsHQAAAIcAPAAABv/AgnAo NAgOSIiywmw6n9BoZkqdajSbrHabiVY0FcEgQSybz+i0el02BBCLRSQysdjvdox+z6/6/1QcgoMe hR6CVHsWGBkcGQECBmyTlJVrBgBwcnR4d3x7gKF+g4KGhRwbU593dRkTAACSlrO0bJiac52Ln4yi vo2kpo4ZfHgTc3ENDQGwsrXP0AUEmXG5nry/oqQcwqqKdscRygsI5QEBC8yx0eyz07gR15/ZgNvd xRYT4eJx5OUI594wE9Cu4KR31eLx6kUvkL1T3jCAmzOnQT9//wKeAwhggMGPaBBu2gWq4ZRt3Aw5 0sOKojiL/f5l1CiQmTOQOAdQ29THJLD/YBCJtaQ4LqZMczRpAiCIs6lOeIwY0nt4aOXQijAvHj2a VCMAAk1z7pzjk+ohYhLzuSyqdeu/mOoAnJM7MCzIp9UmNKQ6LK0+omyNutVUrh+sw17B2i2IV45e X2at5tunLOtFjEfj/ONkJ0JcWHOZLmYnYKwFbUDP+t338rLmwUaTUVyUwUJpxOpujq5VGtfpP6lV T15rua3b15r6uYwQdcFhuh13RxPwptpvh6UgrgZcXHBmjJcbIMtLZ0qE54elQ6Pu+yQhlUL/Yu2O /Ds5AcllRyDXwEIDOOFMMcFnAJChHi3sVYNBapKxVplrmNn3Fkzi7VcOcxkUYgE6FZ2G/wECzyl2 oCUJygHMKY5MxB2EEcqE3EUVTtDPBAwZ8kgA4i2gFwbOHabbiGskKF6Gwqk1H4uDJfeWVjry5+Fp KamUjhwmZuCZj0BSUmIEjdQ23EuBebdVfRdVRI4cTxJpiinLUNkAIwNimWWQ1YlXx5eV0ZekYAtk FY84ALJ02pqEFuIZAuOcZpucc6JRXZ+5rAjhni/CNMcxFvWnB41RFrrmMucog8COPa7TqBmYbFIh VkhSOmGml1q6SD4LekooB57R1CcCXGLQwGEiNpoAATrB0t+RrY5ZaTL6yAgHcxgco6atNqbTFYeI mqdOsEAS8Cgzo05AX33fvcrsMU5KVP8etcJYYK0mXfEaB5zqeJSlG29VRAd/+bWoZGGWWcAPmhJx yq6NEQA0YRzXWoTAaRPcJoACQB6gCbr6iuPfvy72U6dy+zG76aAHn7UMbHZYS5OoelkAYjPqKaBA Ml1aiUxh7h53ETP9VHimQrR2Si0H7r5R7jkL+Hrtrr2W+mNTBhDQJyN0UH0zohOMOTCI1d0sx8jT smulwrAxHBA5XfUpQAPElMptU8QOmbB4p1HkzxxHNYApw+UcU86bQZdsstH1GV0Y2uj449VG/yWN wXmw2GsXAQf057JyVv/X9wL4XRgOTG/ofSbJJROdTr4WIr6VRnrlShOi5VCtjmhNMVD/+eMxff24 hc8SLt/WWJ8puCstJiORx4a/hbQdAHXlMMSz22V7f5ZdWBveAO1X3e+tASQ6OmGvmYHmSl4WwQaH lv1688yczblecS4VVtTxPPha6xEk6FmfzVKmGTriekP4OMCjMQFMM1TiSk3g0DwGsk8dSEsHlzYE i4nhJAEJoEOe/uc4cQiEH3RoFnHQtolyqMl0S3LgkhSXQKRcKyCLcB1d0LGMCUqMYiBRgAbth7Y3 oQtnaGINHbrHoYSNamyH81qEXrSARVjkhexr4obStow3fegwBvrI5wJTjhiGrIm5CAf3+KEwvG2E gXJQxhfRZp+vZUBlSYHDCyEYOjjo/8FpIIHAfLLiPXXJKh5qEeEW2ajE8NRGTIdjGN8eqBEX6mo/ dIGd4/BoEALskY8P253x7sS93zksdM5iEe/KxsZdzTEpaNLeDDXnRGAZxADiyRMfcRQtMHnCSBSh zCeDpwlM9ulMbHxLx1J2Sg75B44a+Y8A6ubKdmRQXLLMXWdeQiMaqSiEIiQj0pz1r196UHF7WhAG 5ggHgSEzIHSxiABa10x26BFMbLnQ7igikYKNMZufBCD5UrggGQWzYz8DFSMDIseuyAU0iVunlerV DgNoEExMUhc9BXWp5XjSbDpqnGuYkzVKmS1x53yhXH45l1BJ8HEMjYYC5MNDf9Aol/+7UJEQlwM6 ABnxMgprYQMPRzb+hBSVVgRV+0J1Do6mFBoMwBQ8YYKoeeoDLbjsJEvNxqubvgZSRWHfYMCH0qRE MgAY+ACPnKcyo0YuGg71z1I1059j6IMkuAyhSzzpsAtZNZFcGtD/DFjUrmqEOTntU9oQFxAfHrUW dbjkRRIbDxrFx6JCZGldq7pCzCXpcNd62Ac2+yGjvQ5SvGKkYSsIDUuKa4/KERhnHgvZ1nbPrpVF 5Bkx28iwbva2H0AmHP6Dqf9or7CPOwztLKFD1a41last2HIuFdnPIUc8KzTH0QgaRdvu4bZjZZyq cgWrBwJWuM9I6mnhaR232oG1y5X/z0zH8Q/oFuY4zBFYI5Fm3euKVaiI+g+OksNUeG0kfqSlRQbn ucE+BfK8XlpuLpvLqvZys2M7stBG6IvdRXA2HSPNJ9KI+Eutlgq8tGBA/dZquaotiIDGVbB6ucfe wjwYUsQYZU1whFvsqqzDGkEboOo0UPSAmLh16O2DAFm1iMzUosx1UF0B6A8pam91hcVtdmlIWCo/ kafofE6WnyO5Sjj0cdEksmMFRqNaKjiXaNYleLgp2NUlTahsmzKON6KZUYpqLghFJ57R02VKJBXM YFJIkXdXBzOfeYjYlOya/WWOCHB2aU+kLlYKs+OhXsvHXJ6FDvWQpznoQSHEEOMihY4817k6aNGZ seN9dTtnOosjYTymYzEhyOdZwJJqauwVqB8nakOfmcFmegubQXZOREmYzmkkrDlmOOst19oSDHiT NxpxjN8Qeja+VrG2Wwyg03mHoDlaGTmM2OxZgwbTfWYDBPrjHl/FQxVovlS2D61gpm7kyf8D9291 pblyixTTAO9yEAAAIfkEBQYAIAAsGQAAAGIBPAAABv/AgnAoNAgOSIiywmw6n9BoZkqdajSbrHab iVY0FcEgQSybz+i0es1uu9/wuHxOr9vvbkMAsVhEIhMWgoOCGIaHiFWKi1Qcjo8ekR6OVIcWGBkc GQECBnifoKGio6SlpqYGAHx+gISDiIeMsoqPjpKRHBtTsIOBGRMAAJ6nxMXGx8jJpKmrf66XsJiz 05m1t5oZiIQTf30NDQHBw8rk5ebn6J8Eqn3Or9HUs7Uc17uWgtwR3wsI/QEBC8IJS0ewoMGD5NY1 i/AOVjxG8+ppszAhn74+/Poh+LcnnACEIEOKHAlHYTuG0aQ9bBQRlz0M+P78aYAxo0aO/zYCGECy p8//nwdNsoIWa+WUefQkaTLUS6Y+mhg13sTZMdw4oFizaiU1gB2rREarWXOZranMfVGl+qNKFcDH rXDjyoXTdSEmlQ9bTlpqdibUmmrVssUJgMDcw4gT1z0ZVu+kbDApOkULOLDGqAIB/NPsMbHnz1kX +5mwUi+2yBXPUk5reVU/jMFiEzYMurZthKIBUXPMl6LFb39r2lTbR2MrQREyB9v89rbz5+QEeGUo b+xj1BafCi/eOq03mZcyWJAuW+BV6OjTj5LezAJESErLpla9nbtl+8KdRri7IDbnneoFKCAeAuzR jntVWNfbfE8FV1lg+NXUQDftcENaBhH4F9uAHHb4/0aB7R0Fn0swMQhcfcNJFZUAq2A0YQT8NGBB A3zkM8UEygFAhoc89kgEiO1goGBZkqnmoH0Q4gfVixntl0EkFgA0k3sYIOAfbT56sAFIWHSwpY+k AOlHNbhoEpORKLbm2msu/jEBRhOoJMkmAUy4AGkY9BfbeQQ9QMGfgAL6ACmRIKSBJB3IgUUkXg7K RqBpBCppoI4OQcEWX54xqRAUlEFBpXMAOeGT153ZYJrdRRjVnTFS6V5SSgXkx5gYZsYnOhvcomum oRR6UAceXDBHB50SsYGwa+gqCbJCKOssr7kqW2wZWUSSRQEUaGmptnWIGUEm4vnm12qs3TdcTTPx 4/+Hq6Q66wE4szaACY57HpSrl5huMG2vHiDkaxxbZuuBlxoUoG+yHmhwgRaSOLrwFtZuMa3Ajl76 rxnXcvpvB17aIepx8wF3ZIoqKokRQ/rUyJR77uqaHAL7uDdevQXlui8xFxOUcxsUFJwtthcEW0Ci akSy7wOMorHzEJEwK8TBaGSMrZbIasmrHAYu8KIFaNanJmtan8QNTTIaEiesLUsCzj/fIICnngMR ZDMyS59TtxpE//z0llAr7cHNAvudxt1RZ5rtA4legMXVcKTCyot+oZrqZfu8OAFUKFEkZNrXJEeV 1gh8i0EDsWF5ztzHEE6O6mfk/TcFQQ8Ke9F/m2H/9Bl3s06t4f12gLjBjLORAAFdBSPjuCiSzKZN YWtd0Zt87IcBN+1y7kEGAQ0mJcxTJBeM6eWgbozudPcbh/nZwm4+tsEzXXsZt9u+vvw3ryH1z5cm KrUbBGQdjtuXS97XmIeWBqSmVTDRjfVwYYHsrWIwoevDvATCk9O9b3zz01kG24A+873vAk6jnwjl l4ZoweF+HhTW/tigh8vMBBAxahGSLmMyjHANc5fQHNrShqGNUK4P2qMJAtwzAfIIQAHmEJ8aPsU+ LdRPCA94WMbqBrssXABUZZBiwTQlMWxNy08C+xMWtQgqDXRKb3prn/vqVzfCSeKJZ3gAqIrlKDnC /+EAq+DG46ZEo3ItLyB8+AuFnGc2li1QE+DojiCyR5W2kcYCVhJH+Fp2NS0J7BYhLEDQpLWzS97C d2YA1i0YJ8pbBO5pyuKdspyWqCgOoWAgRNjNrCU4NUQLlMlQgAK8AS4MdeM1DTQXRsLRJhhFL4dn W+AkGrgH4vDjHwsYnfZAJzq43YoY0XJWCAd2QaRtMBJbROXOmkaETXoqfuAkArBwWYBD/QuMRmNi s4IVqEiAinELYwOjtFDKwW3QDJdU4zIIoDVMAMKgv4TZBCB0EX5oJnrG9EMhq8e5HjZTmDh5Jlu0 JoAGZANu4CuGEv15NWCxkltEkAS1hJZFlBqMpf9PI8IpjTXODKZTpgPb3RYyiTtt0s4Nl8SiKYg3 qgjAjDoyaZJRpWLAhjaTG/2Qlw6VichmIumiroFmRgiTkz4aIkPBqOAxRlrLcrp0aebcFtFCecGg 8VQIwKqfN0k4hLnS1VN/ekP83EA+cR6DAAeQESRPhlAa9eNNLOoHINIFSAOqy5CHZKYLI7oRrK7l H6TxHFVg1g+DCqQ5Ir3gT8/Ju7XCb35xRUO2TEvLnpbVfURwZ76iBUc47JWD/8SbS03BgMBiAEbF kehvjRk9q5qIO47lgzJ/QTJvwGSYluUDNAVRWbYIkYifHato/QlQlGarfRdz4/w8uc3c1pSmaav/ 7bZ0dVr13tUNdiVGb2UUHMWK5w/+gJGBGKSdjTgWIBTVVQYM2yIZ+mEDL0vVZqvLGYAsQACkoZdb jEFW15J2W+BFbW6bZVohbDK85v3m/HIl0Ecpq7223TB3i2EAAjDkRNzJbASAlBznPe8sxQHI5fYQ YA7kCUKvgUr0UpSTnGiUD5cViFYD8K0oBeOI2NzuazXGu+DF96VCheJuh7DJcLZRxLHdsihuq08V T7kUCUgAIESW42j+NpFMpgkgbkyfjbCiH+3iQDDZhOSSbXVWU9EeRy6h2QZrjcniMSISTVHh91I5 pf9M66PP0Oh5ui/L512vpt56PimP1gwX6LDG/8wMCgWsGcbPlJcegbmu7Cx2H3bGr9t6yKZfzjBC l6CJoKu7AEFMExzyqlJsdkSKSkO6u7wCVjjdZ1Mpz5R9p+VyTlcKZkgve57uxW22j926hGFMzKXI B6ozQmjg9toZ+eDvRXyI35wg2Q/fMPcznRkk7O2akYNZzh68mieajeJes53lBr9LBG+u1ZPn1FId aWvtIQCLVw2DYj+jjVOYUmCdnyAzwtDgzWWbEBkQGNdf/JtAHDJEMjcWtxD3YOvteLSBM/yjg5up vSRnFEac4aybrVlsSlIcp1fzpq6u7HBnjdFZZRA6JjNd8V2BQuOf7q6ztg0KFzeIMv0ot3MDIf8u mRzXh8lFEXFTNW/QCXow69Jvgw2b69KNAoyTkqelnih39Hrbi2j48LE4ns236l129curGR6QTWKF QvBvQDwa3HnTZBhgQiIbeZ2m16BXFMnrdd439LzhHSHmWEUlW+TZoflifOOERgJwD1gLA6bW90TN l4v8qpDzlDjFyVTPC5lGWbW8IMMbIP74mpAwcHY+cM30HOEMTSCMIbe7/vkgCfnVRx664coEJiVS N51XrmMC0xABQnrTvOkdvbVVd7PI34ySHcx87wEI+vAniAHWfKpVJfD6K3OTfo6bvTv1cTv7sVAD BERalX7aoxlho351EhD74X5iFX8QqAwKEDL/q3FY1hcIK5Nu+qEfULFfSyUcPgRoa/F9VgUzBvg5 wbY24cARaxOAFBSBMJgMDDA201cc8uJ1eFIiOOgU20eAofOB3KE12qFR0eUPC5ANmsVVHYEBH5An g6Fr/+CCYRWDVEgM8zcjNdgqFoKBTJEd/GUiQqRYQLg834Ijn0ccldWAbLEfIXhoG0WEbDM9L1iF dDgKgSBywXGHDBEn8rF/rkaBNiFrBiZRasImNWcBH5CIVUJzOBFIRmVUjSSHT1aHlKgO9Hd1J8M1 x9GHftiJ/SWGNASCgoFVBMgR4JeIqJiIphdIbvMUEXR6vxUboFWJtAgHpqaJWYgym6iDG6h9/+Jm HxMSisFXMud3WdGkiIaAik7YVXvENkJ4fmwoi7U4jXAwg5cjcgdiIYLAib2ogRwYhkd1GfexH1zT iNDEhE14CIqogjBDI3XSIkL2QDkhYZNIjfaoBmpmfWymNSi3jeGygTvIgypnE8nlTHhiTEUGEOjY hJegiAGBgNxHerAGEBHJBxoyYfeYkWbAAC9Wg4J1UELiY7gIkPNBZ5FzGdATZKIzdlVRJ6mojIwU Nuf3TCljIO7YFheJkRq5kxMoGbJ3cgf1Eq7Wi27CX7BmZynZa8cXXaeXistIkXAYNrrGZ8nnH1Xp Hw+4k/c4f2/GZkDJh1wTJ5QHkJinf78Bju+8F0hMGU0q6FFPKZOmWBxj1zaboW/JV5cakpVaSY0z +GYNghJBOVwYOJT7V5Tbh5YpaRlMpoi/hm9i2DblV1kNlm85OYV7eY+mZggi8wdfFR5jOZhkWZZF ORnMk5ivwQdMODqrCJdxqQ+QyIrrN3p1mSN6eZmV+HgGFW8r6ZmL1QpjGZp/+BulmRHool+bZSfV 1QwVqROySZkXWZu2WYcMIC/2kAncgCCCCR6/SZaEOTaICUjlYop20kj8sFTNeZ7LkZPQGZ1VCAEy IiKjQx1IqH9usp2hSZZClhP6lVXiaZwoaHPniZOV+ZzsGX9BAAAh+QQFBgAgACwVAAAAWAE8AAAG /8CCcCg0CA5IiLLCbDqf0GhmSp1qNJusdpuJVjQVwSBBLJvP6LR6zW673/C4fE6v2+9EQwCxWEQi ExaCg4IYhoeIVYqLVByOjx6RHo5UhxYYGRwZAQIGeJ+goaKjpKWmdgYAfH6AhIOIh4yyio+OkpEc G1Owg4EZEwAAnqfExcbHyMl0qat/rpewmLPTmbW3mhmIhBN/fQ0NAcHDyuTl5ufobwSqfc6v0dSz tRzXu5aC3BHfCwj9AQELwglLR7CgwYOl1jWL8A5WPEbz6mmzMCGfvj78+iH4tyecAIQgQ4ocaUZh O4bRpD1sFBGXPQz4/vxpgDGjRo7/NgIYQLKnz/+fykyyghZr5ZR59CRpMtRLpj6aGDXexNkx3Dig WLNqpTOAHatERqtZc5mtqcx9UaX6o0oVwMetcOPKNdN1ISaVD1tOWmp2JtSaatWyxQmAwNzDiLHW PRlW76RsMCk6RQs4sMaoAgH80+wxsefPIBf7mbBSL7bIFc9STmt5VT+MwWITNgy6tm1yogFRc8yX osVvf2vaVNtHYytBETIH2/z2tvPnpQR4ZShv7GPUFp8KL946rTeZlzJYkC5b4FXo6NPPkd7MAkRI SsumVr2du2X7wp1GuLsgNued6gUooBsC7NGOe1VY19t8TwVXWWD41dRAN+1wQ1oGEfgX24Acdlj/ RoHtHQWfSzAxCFx9w0kVlQCrYDRhBPw0YEEDfOQzxQTKAUCGhxdscNADFFxwgYekgNgOBgqWJZlq DtoHIX5QvZjRfhlEYgFAM7mHAQL+0dZhJAY9cEscD2zQQSQ+noNFFkOiY6Qf1eCiSUxMotiaa6+5 +McEGE2gkiSbBDDhAqRh0F9s56GzwS2MpgkKmAVp4AEFBVD6hgYdEHFBBw+sQQGjkWhAxKKgMkqE mIyKakaZi2bRqQeZCiGmpXQYOWGV19HZoJ3dRRgVoTFq6V5SSgXkB5wYZpaoOaRuoQWtn0BK0Jly XCAqmxRQ6oGnaILaaaVbnOmBs0REckG2n3qg/+oZ2w4B6xBmQivHmxFkIp5vfq3G2n3D1TQTP34I i2upHoBzbAOY4IhoQa0aI206D7sR67ZBUuzoGZ9enG6sZaSLRsNDUNCBvOWWa60Q45IMh63HzQdc kymqCCVGDOlTI1PuEcxocgjs4954C6cDMjERn1P0Guei7C6lHGM8bsdHe8xuu29QXcC2mQq5gcpv GLjAixbUWd+drH19Ejc0yWiIn8TqLAk4/3yDQKGHDqTo08UcXY7eaXA8acVCbPCt0xejPKkZUpvB NxpWb7t1plvXkQorL/rFa6+X7fPiBFChRBGSbl+THFVfI1AvBg3E5mU5Q5+yeDKvK770ovByXf8p 3uUeDrXVo+ruRuMFiAm57WkkQEBXwciYL4ox52mT2V9XxCcf+2HAzcChe5BBQINh2fMUyQWzujKt mxL7MeePamm7HnzbNOK4u+t7yHqnS3wZwF9NaeRwEOB1OHPjHPPI9jy0NCA1wYKJbrKHCwtwbxWD MV0fEiYQnrAOVujK4ODABS5JFG4IkpKEqPSGKTRxjVQdaFPHxAWrTvGvAFlA0wsLsCkPEoECaWrX Bdr1PqgVDlVO452mQmUOPVxmJoCIUYucdJmZYSRsnbvE59rmNgxtJHN96B5NEOCeCZBHAAogB6lK dbFFpesWPSyVuOBXKjPskFHQeiMccQcqR43/8RaDixytmLZB+GksEj28nRBvKAkVIuMAq+AG5bJE o305LyB8+AuFore2nDFQE+DojiC4RxW5kcYCXBIH+WToLGiRClqRgJak3ieJ3ZVhlaeSFizlp0o0 4Y93iRMkETqwLiGkkFtqREMu0SDHPppCAQrwhr0w1I3XOJBfGAmHnmBEPSmyjYGTcOAeiMOPfywA dd0r3enqtixTlO8M5ZPUxVLpytyR7EyOytgNiTDL3BUuYkVblCF7JK4PBvEWM2wnG05pDAMQ4GuY AERCm9mzCUDoIvzQDPWo6YdKYi90VtwmNHHSTbZ8TQANyEbdxneKc5rBjD4cwg79SS2Vqotx/1Sz H0wJd0tCflB4d5CnG4apBp6S4ni3ikDPqCOTKQlVKgeE6Da50Q+ETRGbmNymkzTqGm9mhDA5aaQh MhQMCxbDpGVAqU3hNT+y9i4NtCNrCxU3yKvd02p3bOMagKTBse40fYGLX0IOICNQ0myhNOoHn1jU D0D8C5IHBJglL6nNI1J0I1Rdyz9IMzqq9KwfCRVIc0qqV3SWVacwLGtec4fW+Z0xfnrT68MW1QFn acGQH2uUXdvgUzXglQ4M4CsGYFSciu6WmtSTqom4k1g+YPMXMfMGTKIZWT54UxCQZcsWu6jZr3b2 pJ/FnVjDCte2hvYMNfRdat/aO9jCga7o2v8gaNlQ2zTcdg65lVFwCiueP/gDRgZikHY2kliAXJRR GQhsi5bohw3wrFeWjS5nALIAAZBGYW4hBlh7Jy/Q7rCX8huieQ2Xhh36bZArralLA3k/2l5XmHoz ZvDeRQyDMuRE3KFsBIyUnOhJ7yzFAQjn9vBfDhgKQq+BCvVSlJOcdJQPkhWIVQNQrysFA4zmPDGF U5phgXIYuxoTcWhJZkvSehl/gYTDeoHpWfMuCsOkSEACAPGyHH9zt5lkMk0AcWP6bIQV/RgYB56Z JyTL7KrHmkr3OHKJyi74a0wWzxfDSIoJk7XC8YMnISP2RlOu9qVC8PAQUAWtfmpZCPU0HJr/4zDm nh4NVep9Lx0UwGYYdxNhinRmwLJj2H3c2b5zs2KemsnECF2CJoOO7gIEEU5wIGxLsdmRKOIK0CnP 1pekHFfRQqiFVsZShpHY4Btbe0rVCrFZMZTyG0qdhtpuOwviKjEo8uHqjBSat8N2Rj70e5Er2jcn SPbDN+DdTW4eaXvB5uRglrMHrRoqaKHAoWuzAC0c9rFMJLujqHp0hgew8LoiuwXJMg7I/cmL4m5k 1IblAPE3lGnkNASVMiCQr7/wV4FRZIhkbszuLe6B19sJqQOZ+EgGb7N7SeYojDhz2TeTk0hI72m2 VEwMArTc5Vz8rXIDgS+ZDPeKxUURcHvV/+/SDXowAcPvggP7a9Ul/ewHMcCEXuZyQVmvQa9YktXt XPDpecM7W8yximS2ya9788UCxwmNBOAerhYG7YhHx5o5x/ZfIecpfvKTrqTnso4Cy3lB1jdA/EE2 JGHg63wIW+A5whmaOBhDZk+86lf+9LTsRz8wKRG962xzHQu4iQhAEp/67W/qwS26lh39ZpTM4NOH D0CrT34xDMDmXf1KgTK5x570M1zuEaqR29mPQwmYRasKv3uaMdvwBRWQ11dQ+egvhQJcthrB/rYV OJu3fvQDlfweVThXDPRacC/Vnn2fdMcGN+HAEXCjfeeXfggICgyANg2CFj3zfhUBGXKnX/+0132m c3/c8TXa0VHN5Q8LkA2VhVUdgQEfYCiDAWz/YIBdlYAsiAov1oBCJiMWEgiWkB0U+BtbVFgY6Dz1 giN6RxyQZX5UsR/5h2gexYFxYz0H2IJMCAeB0Hp9EjYM4SfyQX20xn42gWsEVlF3kidAZwEfEIZb 8nM4EUlCJVSdpIRP1oRs2AZOxzktRzNSSHVVaIV2uF862ET4JxhU1X0ckXthGIhhGHiRNDdPIUGC t1uxsVlt2IhEwGpSCIMHsieCUId3aHXsZh8TooecJzPAJ1nfJIaGEIgmmFWLFDcaCHxEuIiO2IpE sIBw2IAHYiGVWCLztyfyR385OFSXcR//+xE2ZehNJFiChyCGAtgzNCIoLSJkEJQTELaGrtiKa/Z+ bfY1M1eJ93KLuHiHttZU08NNhUJNRQYQw1iClyCGARF+tfd3tgYQ68gHGhJh0eiIDPCCjddXCoUk PhaJtzgfdWY5l/GNZgiCNlEVgiKIpMhJZgN83WQzBpKMbRGP8jiPbLh+ktF4MqdQL0Fr8zdv+tWN OpYRwyZ6zSV4gliK7oiEZgNsfUZ6/uGS/uFVFMmEzAdnbZaRVBg2fvJ22jh904eDz/ONiBYY5CiA IYWSC/mHxbF1crMZBEd6TqkhMjmTLLiAcNYgKKGRv0WDHEl9uEh7u3h5rcFkYlhsAqeDtHLje5C1 YAMnkStIlS3IaobwMn+wVeHBk1zZkz65jTgWkCkCMCSIOoSYlEqpD2hYiMTnd06ZI1MJl+indgm1 b6eDEiA4b5fQlU5xhb8RlCJJM/hlWYMSXc3wjjqhmG0Zj43pmMnHAAhjD5nADQiyleDBkz3ZlWgT lnziNcPxh4PSSfxwVKYZnMshkampmqoHATIiIqhDHSC4l5Gnl9ApZDmBX1XFm58JgEEXnBHplqhp nEQSBAAh+QQFBgAgACwRAAAATgE8AAAG/8CCcCg0CA5IiLLCbDqf0GhmSp1qNJusdpuJVjQVwSBB LJvP6LR6zW673/C4fE6v2+OGAGKxiEQmFoGCgRiFhodViYpUHI2OHpAejVSGFhgZHBkBAgZ3np+g oaKjpKV1BgB7fX+DgoeGi7GJjo2RkBwbU6+CgBkTAACdpsPExcbHyHipfH6tlq+XstKYtLaZGYeD E358DQ0BwMLJ4+Tl5udrBMurg9DR04u0HNa6lYHbEd4LCPwBAQvggqEbSLCgQVDqVDUjBA1evGqR MmWzMAFfPj77+CHwpwecgIMgQ4ocWSAhswjPXjmcJS9iPQz3/PhpgDGjRo7+NgIYQLKnz/+fxEyy U7lyirx5LgvxkpmPJkaNN3F2BCcOqNWrWN0MWOcHUVFqECXpWipT31Oo/aRKBfAxq9u3cLcqjHDp ncOWtySSnem0Jlq0anECIAC3sGGfck9+xXsLG0yKTM36/avxaUAA/jB7PMy5c8HEfSasZHztccWy ks9SVsUPI7DXggl7nk37GOg/0xiLNW3RW9+aNtHy0cgqUITLwDK3rc28eSgBXC3IIo3tnsWmwIev PttNpqUMFqDDDljVufnzb6ArlK4o7G6K11NPpqxdFUamdLEteK15J/r/AKohgB7MsMfII43xhtpv 8wlnE3ANcMPMNqJlEAF/rwVIBAUPEPT/AAUUaFjKgOsZhWCC8C2YXX0O7iOAfd1FsE8DFjSwBz5T TIAcAGSI6MEGBEXSQRwUXJDFBeaACGKH55DIDAZh6QWZitmtZl9lTkUoIz/5QWLBPzNJhwEC/MlG EAW2pBkiKD8OdIEHFzzApBsbaKAkFmyk6UEHawqhp559PgDoGRvYAiQkQwja5xxO9kFNXuBNyReD qv1VX01aToDRBO9EokkAES4gGgb7vVZekn9CsugdbaJTqBx8KinEA0CqAckGHdgypBCFpqrqEJBc oOSvhNZaQLBCaODBqnE4GWEGKErq24rBtViZX6LOKKZ0SEUEUB+OWnjZqeSgaawprZ6D/ygcGyDp gQZGLkvBuWasO2uuSNbrARpv7ioEBR3MWUYWwF6wawcbMAtHoxFgEulpTcnHoqXB1TTTPn1sC62v 34DbwCU6mjqQucWka469buy6LK9A+nsGyn7uqy8ahSpMs7H77jtvwnY4WxzEvlFaLVSqLdAXSvnc qJR0vtpyHAL6SBeeyOeQTIzJ5cC8Bq1+2olmhxsIXIbWub4ssxk1v0Gwn/NiMa/NbhBodDNUVrnd pU75sQ1NNBbCabdNQ/KNP94gMGqpAqFKLylYk6O1GvN2/eYQPKOhddpjn11Gv2rjzCGilc+Byipa 8kWtlay1pk+meVtCEZSBR3ScVEYj0P8wBg28ZuY4Vg/T+DiP28p2AR3k6/LMA6+ceRq30un5sRoU EPobCRCwFTA0Tkrt0K3h3U1Fmu5BFwbbbBy7BxkAFBiYUE9xHDC7I4Pmj1tkITDPGuS6p9gF0GqL u4srQP4iwb8CvImAZgBYJIAUOSHEi36LGiAkojeEgB0rRIISwvGWx8EOJjAScBsGAeQGDsNNQGgT I9qDzNKA02gLJrg5nyQsoD5VBMZ2fABZQHjCO18t6kf6E5K+tgAnrM0vTfQSlJqIcEAknq1XkcjX sf5EhCH1KUQb9OABAxi8CjYvGXmozEz+MCMYca9ov7HARTIGk7/J0EIbwRIf1kcTBEj/ZwLiEYAC koGmWCkJRJlbVK4EqTxgmUyJZVCWy/CVrD0RAWb686D0TFYoYwEsUHxaQ6ooiDw1KLGQxTiAKrZB ujDZqFLdm+Mejiaj7/mNaefLxDe2Ewj1SaVworEAmcIhv99JUlDGQmQiTUasKhYSZYsqlBRnBbNm ai5micxVBzhpK/odqZoF/CCciqEABXTDYRbiRmtoSJ+agAMjWsIYStoIu1jSUA8O2sg/cLe+2t0O ceQiRe+Yt7h0vYmawAqmLx2pwYE+s6Ba3GbyQpingzIPlJ7sIigMQACjXeIPFxUn1CZgqTWSiUDi 7MMrzRc7OMKznLb8hzxp1wABNEA//7ozxj4t109jYW5sxnqTzVCmv+lNkVDPRBkU/8RQWm1BYBIN pNoUagrrPSsCUENJOLdkO6hCpYVrhOc2+PGx1wGuabKEJ4tOyhp/aEcwOTllIS4EDB4OY6Yvqynl IOonm9IVmky0xZwe96pHaq5QXvsjINdwxGL+1A2GJawvEXIAGunyPhm1ET809SIu4cMpemghxmDp ToCIcUv7yAlgOCKa2UkFavy4aECWUwq41kuuDmRqovwpW7+eQYk4c2hfDUkEZS0zFEn1K0M3tNhP MKCxGGilOtdK1T6IFWIe3SjG3hg+B3UVI6IlmlkDsdJb7uOOq31rcev62iH00QxvEv+oQ12L18NK EpkEJcIDfiuH4BqSWQ/I5DDpK4rj0ug3XAKPH/ohIwJBFzsb0ew/SKqnDEj2SsCJwAaedrfTrlQz /1iAAEQTMraYgr2PhG3MFoXb3r6rDMJ04DLtld4yzO+9EB2kHew7Ym3qK5sTJQBKpqWd0kbASccx Gvh6M5x/nFAPDJYEqSyluuGAa7Ty3EOUMyIYzcyxYV8Chh716cMQl9e8twJRerEGCX/Nb8UK/adf /aXIoD7zgBRUYADhQOMpKkxZypvfnEORgAT8IWhFXsBaZxmAi/wBfJGpI5isaj4OkLN7UlYhlZ+c lvVxxBKmxbDRCg2ePO5RFIVdYkD/v+zXBR6LvkNNbKgPGsRg7ZZXB101QOdQ58QOAc+2mHUpFPBn Hof2Y6QcZ8au8wcEL3qycOxeSKt1qQVYgiaWXqmzvxSYTX9sTK/p0U9kRVgjtSsNWPj2GXamazZ4 e88EOWoyLpsafmBauWpECT4OfJE4Dli06vSGckPbIpGmL9opVUtyMruHQuBTRAgfCQQm1ZcEw7B1 KIEMotnN72VDCDyoTOW3PNtdnFSadjLSDGoFTSqqJfzkBNFxxCTj7uS2EtjWYQp0FS1dM96He9fi d+0sXW2kAQTDkn12TFFOdHMYIEJBazioyBcxV0hKb6jht2ZV0fBVYozflVFhLXlu/9YdB5wjNhKA dNg6mKKbPRl+PmHSnzJtvnCKUzHR25AvJs9spbLJ+VBpHLcDJQzwfA9q/HpmCKfh0g797IgfxsJX XnW64AcmbaQ3outt1hNSDAFQ0hTWJS2+wXWcI3tYH2YGzocNi6utiU89KQzw54hhC4YysQfUZU5k 9YnqlNmhC0etZE6zzpHrHMGM0dSnGWg7foeqT/4nFAC0dhvO5axY2rzxgx/M3siqwIkjpaMMabFC TfBqsSg9B084f+ge+cpPPx0YsDfGD+djMqmIYyR14MljVg8DvtIqsRPa7AJmAdhgWmjVERjwAaQS GNBmfuSDfurXgG7AejXiftpCIf+AUAnXUX+9UUdcgn0ZcR++kGF7RzTydHxSQRfat2nh139gt4Co 54AuuAaAwHC/EYPyVhdPd2j40Xw2kX82Z4Ko83tqYUcfMIRjAk+nNTe203HAFl4v2IRmoGMnxHD3 EW+AsC3EhoO0ZzrEYVU2NzT+B4Q5UYBDOIYfEHCrZDhNgUM4AX+vwVpO2IS8Fm8SiDTFUR1XiIXx d1n1ESE51w/x5HHSJoaGMIYHmFalRHh8iBMm2IZv2IjsF4UrVyAUEgh2SH1yN3uJZhN82Br0QRdq 5HFmJYiDaICDk1k2Air24RTdA3odpmWN6IR+Bn2AZjQSR4mRYomXmIUIxlXVpUL/o7IlORGKhGgJ RPhz/6BoHNEH+rARw7dSe4AhHvaKL8gAO+Z+joVRUMIBsIeLEDN5WtgavTg3AWgTUwEqZEiIttSM OBFaSUMgp7gW0BiN0tiAzAcZaxdxGPUSdyhzchcfGmhkHWgcHAcVa0iGhXiMKoiQ0NZ9mcEfwYch bjWP6cd6yXWPxsEpAsYpTIeLmEghUVcZ1bVpfzFPpfhSB6mOOTEcVAU17zgewdeQECmRDch+FRkx 65SPLleB+xh//aiDIIlzGxEBRFhPCShafNEa7QgOPBePrxGRMpl6vFYIQdMVyfUdG6mTHImJeFhv 4MhsBUeKZoiSKZkPUOWOOoFhg8CXHDH5lMl3dBelb7ezTgE4b5awk1qJhxp4Ix14HwV2WqHijMyA jEaIlsD3kNDolGx5dgzwMfWACdvAHjnpHRvJkXe4N3mZLXITHKAXKt6VhJ9XmKI3eoeZmKoHATRi IrgjVQHYkZOZlbioijlRYGW1mX3JUh8HmgLHlPGImKTpHEEAACH5BAUGACAALA0AAABEATwAAAb/ wIJwKDQIDkiIssJsOp/QaGZKnWo0m6x2m4lWNBXBIEEsm8/otHrNbrvf8Lh8Tq/bz4YAYrGIRCYW gYKBGIWGh1WJilQcjY4ekB6NVIYWGBkcGQECBneen6ChoqOkpWsGAHt9f4OCh4aLsYmOjZGQHBtT r4KAGRMAAJ2mw8TFxsfIeKl8fq2Wr5ey0pi0tpkZh4MTfnwNDQHAwsnj5OXm5wUEy6uD0NHTi7Qc 1rqVgdsR3gsI/AEBC+CCoRtIsKBBOOpUNSMEDV68apEyZbMwAV8+Pvv4IfCnB5yAgyBDikSXkFmE Z68czpIXsR6Ge378NMCYUSNHfxsBDBjJs6dP/1El2aVUOUXevJaFeMXMNxOjRps3O4IT97Oq1ato Bqzzg4goNYiSdCmNqc/p035RowL4iLWt26paFUa49M4hy1sSx8psSvPs2bQ3ARB4S7jwwbgmvd69 he0lxaVl+/rV6DQgAH+XPRrezJkc4j4TVC6+5rgi2chmJ6vihxGY68CDO8ueTerzn2mLw5a26I0v zZpn+WhkFSiCZWCY2dJezpyOgK0WZI3Gds8i09/CVZvtFtNSBgvPXwek2ry8eTTPFUZXBFY3Reuo JU/Orgrj0rnYFrjOrPO8//9DCKAHM+sx8ghju53mm3zB1fRbA9wws01oGUSwn2sAFgAJOh1EIv8H BRRkeIaA6hV1IILvKYgdfQ3uI0B93EWwTwMWNLAHPlNMcBwAZBBky4+gbGjOA5BccAEcW2wQohoU RKLFA0Rs8OOPG0QJpBkPZNFBFgVc0AERHizp3IB9YABWXo+piJ1q9VHWFIQy8oMfJBb8I1N0GCCw X2wDTenhJ0KWc0GYcDygQQEgCvHAkWk0OWWVQkjpJySQdunBFh58iYYHQ0i55KBizkEiM9Tg9V2a ey2Yml/00QTnBBhN8E4kmgQA4QKhYaCfa+SVEygpv44jZRxVUtDBBZ5SwOgZTYppbKZnBCtEk5oK gWwanEbqpRBbhirHqBBmgCKqva0IXIuU9YX/64x4RndURAD10ccUxvHaZ7alSIvMsG8YiSik11Zr RrNl6Kuvp2/gq2SVWSppx6jzZlJdqqqe2+BTNMm0Tx/tijupB9/I28AlOtp7jr5B4ksOv25AaiyI Dm8AJbOEEtFhtCp3WnMbCoOIRZbexgEucaYxFR+L6LLG10n53JhUdB/bYhwC+kQHnsm+5iwKysaw 3IamL9fsMM3eIlyw1pYKvEbPGn45Nh1kwmmBmmtq12pTfmwzE42FyPpu1JB84483COS6q0BZD8N1 MV6zcUGIFFS5bQGVDrxzpJcLgTKlLQ/xeJdHfk4HKqvAuZe5bK6m9N55420JRWYCHpFxUS1g/2ME 2DTgGp/JUJpk5ddKWqQZGgCpb4eRLDsEkbaYIfylGjI6qC3LPoA8JB2IWSykHkB5KBoEg4k218gH bUwCBGgFDI2pmmsxa3d3UxGse8yFwTYey+5BBgABZifV9AoI747xMSttYEtZgMTMMJc9mCGvDNPD lNqwl0CVUTCBHXKZpLIgJt8dEFrTCtr3wOcBDYAocsMzw+Ic1b1kEIBM4CjcBCqGNIw5qCwNMA27 XnIb/UnCAv1TBWAQIKMFkCwgO+kd2qwksEFVi3lleKD4ytCkygWKAiOc3tkq1zgFis9ZSgLRtZjk J/NpaIlWypwp8kAZmfxhRjB6X2psR5O5uf/uJX7zYYU24iY++G8mCIjOBMIjAAUgY3GUy1ygpKQ8 zansZs5roebUNoQOeWtQXFQZkSpXgE1CcAMmZEOTTHhCNSByWpAwoygOoIptlO5ONloV/Py4h6UV 0Xayuh/U9JeJb2gnEP2LCuFCYwE9hYOAaMScCvFlMAtSspMlrCT0lhmtTBKheAjEVDLXED42nHII 36yDAhTQDUzQixusAeJ8aAIOjMBpYyfBY+x4CUQ9XMwfRhRcWmxHxPxgTXHbbNwZwTk+fFVxUwIT 3ggHqkJr6mxSnIxk84bQzbVt84vDMAABbHeJP3QUnVSbAKsuso/L1C9OZdJl/mS3R3uuM5j//9jI PhsggAb4ExgDBFZAtRaoZlJ0mtQsQ/FAyNCCORRzqmRSkohQUVNeVGdJvUP6whUBqp2kQiD1w1ly SFJ7boMfI4Pd36LWS3uyyKWrwWdGAoOTWBbCQsBIoikQKdBFSnKKBD0DJjdVM2kdVGdEGNRCP9FU bC1xgVAdBgEOQKNi2uejNuIHrF4kJ3w0RQ853Ngu6QmQNqJUpn65SWhoFxWq8aOjAVGOTtdQV4NG 85q/Mhtep2WlJUkJsQXIoJXO1tA6FJavOAuqKRjAWAzcsn5vjVP9zFo0koKVfgvQI/0aFFaM4CQ4 +AyETNMCSEGmdq5hOmEpActbaS7remdT/14KEznCQDFPe5wj70OX16FGwuG3wTWDbqUZUVEQl0a+ kdN3tLoRGQ2oudfZSGb/sdIpZSCybfpNBDYwNbuVdruZ+ccCBBCakq0lX5PabXmlST1pXS8SoWIe 9Zg6pb3KdwhDXbFv1QjcM5w4vhklwEnKlZ3RRmBUxsHl/MginH/MUA8NloSuWKU04cjrL1LZA2jX yhHkaDgAuKsTMAo5CvF6mQgPCFqiPslBNSALe2gYavawhDyZIQqxYWYW8tZ8h6gyVZVewp59SZGA BPyhN03ZiBGN60ssz+QPQz7NPuxUVQTkjwPqhJ+UbbjWJ6PFfxyxBGkzbDssf4eQhhSRqP8HooA/ 83jRI3NlOjlmnT8kmNGS3SP80Im0Vi3AEjPB9HZvXSfAdHpkeXJNj0ZNbHJYFjX80PQt53YSfCD4 InzU6nXh6Y1bLrpFZeKfrmGaFiubdtCH61Wxx20KCFCsMmElKdNgMuRjX5vW2LEpEGsIoytf+sL+ k1dmvl2IcJP734qlGF+SbdwipnpiMWkuIDEL3RUp127X5iemfc00gGQ4srjeHcA3LgoDQAjQA7fV /YzmClTlTdF8zKwqBl7LjV2bMjYE5sTxuWNuc8RGAogOXAXD8Z7fwc8zBLlTeL0XWckKJnmbn2UX beSMbOfQIesHm4zIAQxMfA9zszlmBrf/4dFq3Odgl4O5jRYZORU8Ji/B47MTvXAjQzhdCDATrF5O 6foJbrul1To4AqJWDlcIiWEPvBsM8GejqYuHaH/ayZeicD+6PY7MuF/q2KlWvQPmMnTcuq0AMpd6 9UfwoEeDAop26ozIKuHPQHqr73PZGzX6N3y0NGglbVaqWf4mHMWAPi/uj7l4WK6hD74QGKA3sgd6 ZAnPFR6Tz3jSO56Ir8+O7a7DdLQ+hcHGvTxOAoCBD+gKMLnu/f0AL3zhE75GxhcOjSYEiEpYB8EK B6Scoj9L3OmoyEwWP2k5MpfYd3qf1Tc44xdX5Sd8gCBwNHGAzUYXJodo90F68gd96ZIx/3kyeXoX SB+QgXliT3kHIUSEdyLnYapVgGGnYzN0bgSSN4FAHau3du42HI0GeRZzXfBTWt2XgTj4AdxWS4XD FEQEU8jnGiNIgj1XasyWfhyjgu2yeg7YfBpTEx44S1JnQ3h3aUakgYWAg9/XVq/EdR54E/0nhEQY eMR3gmRHIBOygst3H0m3eJARgVE4acExF3NzEzJ1hd5nCBqoT1RjI7ZSH4EmRDjhYVs2hmDnZ2cH aN3wGICwHsXBhm3ohAn2XBbDB7kSJ9v3DzfofZaggRb3D21Hc/ogaKG4BxfyYYbYcwywY+nXWB5l JlV3hJBYNIl2OpQxXbWEO8ZVE1JhK/85qIXBREd4t2hNMyB+qBaniIqpCHCj9xhCdxJzIysuwYSM l3TwIX9Nl05ZZ3141wA5uIWgGIB0lGu0hxn7UWUXAnzLOG6ER2iKCI0eNWC5RI0JV4+8EYHrojTc qIn6ZFPgKIwcsRoPRzjmmGGal4zquI7ERnyEZjTxFI8F1370uHhK94KsgYuhFQEamG/hd117wRrF uHeYloyukZAKKSKlVgiAxhXG5R0jxwovCYlu2IQac4vnsjHdp3s7CJAB2QdfyIN8N3PouCMmeZIA 4nEdVW26GE/Y4GowOZFOyXw1eZFOZx8GVlq3sl0KUYo5IZSXh5BGWWwMMDL1gAnbsB5IEdkdMSmT TKg3+AgrZAIcAXkrwrQPjeaVeIkcYBmWowYBNGIiundVTemGRieThgkZRaYHBpZWc3mVtRNZeDlx JEmSRcmXhBEEACH5BAUGACAALAkAAAA6ATwAAAb/wIJwKDQIDkiIssJsOp/QaGZKnWo0m6x2m4lW NBXBIEEsm8/otHrNbrvf8Lh8Tq/PDQHEYhGJTCyAgYAYhIWGVYiJVByMjR6PHoxUhRYYGRwZAQIG dp2en6ChoqOkagYAenx+goGGhYqwiI2MkI8cG1OugX8ZEwAAnKXCw8TFxsdEp6l9rJWulrHRl7O1 mBmGghN9ew0NAb/ByOLj5OXjBKh7zK3P0rGzHNW5lIDaEd0LCPoBAQvfwOYCChxIEA66ZRHYuXKn CJ48bBYm2Lu3J58+BPzyfBNQsKPHj+YOqkv4DBrDRQ5tzcNQr0+fBhUtXszIDyOAASBz6twJSqQq /2evTk6BFw8SJkK7XN6DWfHiTJoav4XjSbWqVTMD0qk6JHQaNZXXkrrE19TpPqhQAXC8yrbtzqwI LZlkmDLSUbEvmcY0axYtTQAE3AoePBDuyK51I11jGVEp2b18Lzb9B4Bf5Y2EM2s+ZpjPhJN1rTGW OPZx2cip9FX8xfpv4M2wY4Pq7Eda4rsRJ3bTG1Om2T0XVwGKQPmX5bWykyuHI0BrwndfFY+euLQ3 cNRlubmslMFC89b/pi4fT55I82UWGjoyGpZ0aevXI8fvrTSC3AWsL98sP4SCuQda8CeKAHmok14V 0eHm3lK8QcbXfDE1sI062nyWQQT5sUYQBRx2yP/hA55Q4IF/5HTgQQcbuEGBFleQmIaHHJYB44xl bOEiETAW8MCNN85BIHpDracSSwvuBp9vTjUlQCoVSRhBPg1Y0IAe9kwxQXEAkCFQLbWk2ImIPR5z Ihwj4uglGlw+4mKaXBKR5gVmcDiifxt4MESdnfyoDgYJhtVYaQ3G9+B8TDlpkX0ZPGJBPy+lhwEC +b0W0IkzgvhlmeRg2sYGO3qQRQcFcJqGpzuuqKYQHmrggQYeDnGqEI+geecGcBZgYp4F8jGNLZi0 BOiRqKWmWpN9TFDRBCZBkkkAEi7wGQb4sSbeOJ6WAmY5mrKR4opCdEDnqGcWIGK4qGZbbriWnmH/ pxAbUADqBResW4eeEiYqna8MAosdhE05C6Wj6RVllD986HohZdMiUy0p12YaJhoX+Ocuhx2ASK6b 5MYqo7niLsyGvO22C6q8dOipa6+55WXaafL5FtNL+fABsL1seuBNwQ1YcqW05ngsSsPUPnxGrRN7 YKkG4NZIcrkPa/zxnf5Vu7Qc9Arn3m6BIpkkoRUldA+VSKVXM5fEIYBPet7xnOnFnwAtDsdoPAAn t1mwmzQReG78cJ21rnFmxKFa3EmuTlrwK3zBnrYAU8VSFCUhyAo8NiTe8NMNAs9GCxC1nm7Rbn8j 1gnJxReY+EinPT5g+onp3gkJqEpDQkG8rnbZ/9/qmoLKbQF2atC3GT7zDjuOcNvKekCnqOJkXvru Kxk+Tk7AeCUR8Tl5NcRBtTgCEVzTAGuSisnmmSKeqIWJN8bLZZ3pm/+pB7+rn4XTvHc+/63s1oli 3+5vgL4QqpMR21zlLQ6JLkxuK4P8xpEAAmTlF1FS2ZG0NiyZLI4bEjGWHuyDAW3Q7HoeyIA//MIo s02BOL8IXzGCtzGSiWh49SvDqzpGLvbVbghXGEK8fvcA+vHuRj6kH4oM+Dt1cakDRWSa32ZIDALk 6huYk94EE2dBsjSANP9iSW1AaAsLjDAVfuHeHnT2D5yIaYDlKqLTVNUjG3ZrasK7oRHNkDdXuf9I REXcoYyEJkM0Eo+PQ+hh8UKBB8m8xA9QYpKgJMO1ihhuekSyHhcvhJHn7YGEMEFAeibwHQEowBgs /KMM5eXDjq2JbXUsXxJZKCIZukh041NDqT6EsTYkMG5jIsYBUqEN5TVqSiyroD/0oJcJLQ5ZHRQb FzHhDewAYoRQudxnLAApcKzQjwl0WikbNq4zuFFHtThlnJamqTp5TguAhKXPQjlOQOINjqBQgAK4 cYkTbkM1XmxZRb5BrCdtkHqR42IkvJiH3+SDHwvAQOXQsr3uQUttwmCnEt1EyqlxM5R1DKTpXEU6 cr5ykGmYJQVaJ1FRbgqenzAAARZnCT+09J7/ZpvAgyiSj8ps0J98gJwyJxmBSu4Lmv3ACEMbIIAG XENzKhRFSbMJsqmxUY6jRMNTY6g0V4LuYkijQ0lBFya5mQF/pXBgvXoqofS45FA9dcoVaVpQbegj Z9WT3OSYWVBBFXRYQr3OX2oCTEJg6BdmJMVSzeW0eGW1di6KVw3L2bd4keibHfMoRZXmzrut4Zal zGVYDxAlanbtpVPSh7GWpA8/wGyYV4zZTkHIAYIaEqdC5QtNPpM9qJhNHy39B3KUyqa+MZWiXhJk tvQXsdKtc1VyItkjWGUqsMKKR48orujqsNWJEkGQ7aKAqow2DAZwFgNPAk5OwevPDda1SNdJ/60e BNoLrXGDJfu8q2QQCgihoiWTm9StYHvL1RqRC3cjMpf6IFHE8skudtGlnZvCdEQ7wM+WcDMwJFpH Cu9GiTel7U4f9vGkAi2oOhhJbT8+mKYMhJZJiuTDBsq2L9va9zL9WIAAPrMztVBllmso1YtidAYd x6FDH2lVMVSaECNdh7YR0BNxjpnBsQCnH9LLA4kjAa0HqYYpG0RSTWpy0AKdxTKXuWT3FvULTwro zARJQAL8gLUnJxS8zQwARfzQ5PdgRBX6oFlrLRgzg1qEUTIhIVQqUVsYL07O3enkJ9HM6HIogM1G PmjOeolPmVHHtPi484YxR8lh3XOREKoETP8Ebd8FAIKEh87Zo1ijpUa7+hj2iLRFCB1eUzPDHh+m SCU3XBM9bLAbtT6on3MqQlIDFS3GyUNfH2rNVzt7GBBQmV5CrMXpJaQxTY51JvPwaesY1YuLFGaM C0rCL2vvSZe57Zs1l7Bnu9sOBJD2tDVJ3vf+IWUuQW8l1Xuk8v60ktsTtF9k1mEYh1bU4Hu3wj1h AAlhbdrM6iCDWvGnfNtZ2RrkRnYy+eQkbe2ZAkdokY+dkSkJwKwJX7jK5bBm6T28X8NZCrKQha8M Xq3L/qrglflws30kjk8YELgeDEdyy1hOxrRN+cqX3oZoM+gxpSWvS1hCpFzXedtQPjEjEcD/J2MJ 28+/3nIYi/6NfyAU6QcDLNPXbgo256tfWpx62BqnFPSO0FnAtI59ZErFS56d7H6pzAWNzix/2AeF +2G74omggKuZRrRS/0PYcF2f+jDFw2ntDcD93evU1NVsgKcJSxWaEYPzY+9lXLzqC8AAbTi8zVCK /LOIlG/qXN3v3Mv8dRZXnS7L1ykjBm/gt4yBD0DLL6M+fQdTv3q2G6DIT8dylCokeaTY/vp2Lq3u K9i9K3X8N0I9PFrsA/BDM9T3llu+2pu/9j/IOybuTwiy2lMfq2tbJptOcU6DNaxyW+ADAPgo5EYT xNRTPRVN6mdj7Ld08SY90tY1hiMc9Fd//5fmePiXVvqnNZ0HRgRYfAD4gR9wbMSEOUshRjSRM3+l gAu4cI8WgdFnIMUCCBNIgTRIUxchIYz0ZwZlXwPYDx5YCB94fHzlS0eHgzRBfqyxWyvobq3ngE9n IBUig7RXeXRGd46RSW+FgRSUU4ZDgAj1g0BofAtlNlPCLEyCZRyYBzVWZkuocGsmdbA3fRLYHS5Y efbHPDeoQQb1LP4kdgkVhJUQgP4geFgncpnWD4WoBxmigm3obAwAfS/XWS7FJxwQd1RYhXRGHZmm GnpYgNfAefbVACAYhNB0QTx4UF9TIGWYFovIiI3YaI3XGC93bS61Epdmh8XyYZsIZRZhav9E93s8 KIqkmBGmKHowMWp4VXr5oYz5EViv2GjPB2dtRovzZzjIdIv1Z3G6gYVU0ovN1BcJtVBGJYSI6Hup 4W+XA2YwRnit6IzPiGatB2cMQhK1SF6Sh411l4tXx405hxpyFoColny9lheqkYplJ2ityBru+I78 8WiEgDV94FfcIXGrQJGXaFq15xgW1ImqoQfFp1AiWIwZ8WsHOIJmF3LKiCULyZDk0XAtBWwORRKf iGuVgI8WV3e6sZG92DUdZlvNYl/LkIg2gZKB144sCY85Mw+XoA0HYo/bYZGXiI2ux4/Gkiu+MZLN Ek35kFZE2ZXGYZRHKSAQECVBolDP8YkeVjhzF7mWpxVbHeZ5WNmT2hNaXSlwCZmQKxmWVxEEACH5 BAUGACAALIgADQCsABUAAAb/wIJwSCwaj8ikcpmkXC7MqHRKrR4p2CzWatx4uODCxUOebs6Xh/KB VRu1cIpbqJ0TtfS7lMznU8JCXoBWXnZKFxtEG1BIXn0dc32SHolCk39FFBodfxQemJt7n3CDBYKl U5RmBZQbHQUahkNeWWMejFodo22Bt0Mer2+VFB3BHZVMZaiKX8tRqlGMzYimjc2/17PZ2ESydMOu BQ8ayEvKzqbb6EfQTNJYnNVHp9xF9ETtShTgF+QP5UrOObu3jh3AJJU+xZPXZRvBdOzUXQHH6tVB JAKXPSyI7+I8S+KCeST4cKOXYPpwQVkkRtSlWRs88Tmooc8/dY7yCbGlMx0Z/4vSJA0hxgcSnZWB HlzA1LAbsKZHavriiO2lJUpZaDE7c4bPHWBcdTFl1UogGa6OhnnihEnmMUcwiVCzFpbM2F5JHujy 4G1ZxiJ28aF8kE9mR3vXPDEaN2QMo17l8j1t3G7fmQ6P50na4G3j16kF/+Lbdu7huZrsNNDxoNrI X8nIxhgSzcQz4ii6+g6ifRXwtb/0jrFDySfNYcCRkeWcdAjtHNvM9qBEx5us73rRLV0UyBNZT9ja 4mxJIokpdG2iOFbPeE6XEfeBpv+SX8CwdtfJh6DWKBFqsv67AWjdaOhdt9MnmYD2FSbwDQWeEIRl BktrVZyHVxFj4KfeLlkQ6G6hOJMJsRcRujxmC2WUueEJhYQ92AtTnni0hIUQJWgUiHxtaNWA2Ikx CUF7FeXUI5/N5KIQUvUBBo0b8eQHVeLdFcU4Z6jGhhGIoGGEUmdI+Y+WcjBhGUtgXMmEmVFpSdWa bLbp5ptwxinnnEwEAQAh+QQFBgAgACyCAAwApAAUAAAG/8CCcEgsGo/IpHJ5pDCf0Kh0So1SPNXq w8N1MimazSVLLic33DS3fDVbsVDNuHDxPJJqz+ZeuObVQ2hpG0YXaGIFHnN1UGgUj5BscG5MaI0F G5ljHXgaYYJzkFcdokJXGo91GkeTHpwFHYRPlpSmk7Vnt0kUY3AdDxdzRh5eQmtFekYdt3zDQ3oP D5mNumZtuEq0S7LEFL+YSMRE2s+yRMdLrdJ75tvVktjZ78rG3l6vw8WY1clFy0+tYHFqJw/btXhH yCVBlajAA05gwulTmIhgH3RJhI151IfanyFX6gAi4odLB0Yk8zQzNoiISJMoS6JblgYfoUUFVkk8 h69cE/8uwhDuy0TUnB+Qis5tgCTIpR6m4oSgucArqcN+F2+Rm5qqHxg+0vQh+zjM4hCRYnFRRBr0 nxC3z2658jcJbjO4b7VO2qJTiIaoOYmmi5UprTGz46zGW2uriLa5TpGyCoX1WU86eof8pQrpL2Il gPF8DmQHIeOLjlsRPLgWqyBSPlMmJv1H8bCR9ZhURnJldJbTB6WqLnLwL6t2D/6Wrkg8s/AphjSd M4zM92HT81DPNnbZuK2VVw33g6zZOWaxfaWEDkcw+bD0tYDr0uZdyBa5utB5iv1XH0Zy5OW0HkDU KVXEFu2gAR4lguQh2XYsUVUHOX4QhREXFhaDYSZ6mIdBWTdoXAbFgGUV4gqHu9VCQVGCgXSgWA1e II0RDVr0GnowzTjEA2J501IVe1RimI+uBCXUkUgmqeSSTDbp5JMFBAEAIfkEBQYAIAAsfAAMAJwA EgAABv/AgnBILBqPhc0FyWwyPVCndEqtWosXqNazvA49G++V4qE8pA8NhXIJI7Nad4G83VKEcKim SNmAlx5nBR1yTn4biIh3YgVgjFV+Uw8XbJQFXUZ+bX6BBQ+JHR6EiIJgaxpcRh5fboRUkY9FjrFS sE5LG3dta0e2jR18ZUWoRIuyrJdtr6u0yM1Nvky4akqXvcxCxMXCRNFH2GW7hdDYzbPPSN5Hdxsa iELG3eVkwfGXnU3gjZTjTOpCD+6s4cVnYKNxAQkWVAjPoBl4oRgONIbrDjNM8ohkqacK35shS5YE XFYH26Ete4aEinMuSZ14nKJ82XJICE2AdYBdWnOGXzr/bA9EccwERhA6eRMValKJLUvKQedCEUFl FF+HRVmMoZLjq2WqOZj6DYkJRec2e0PoiG32z+U2prLcBLUndA43InWduYVXDuqQhGiR8lx399ra WG190bOJ8SCevvdmdsBY2LEQW2S3SEsUFvJQf55pJZ4Hjq4bb4v5QilleqzJMkkD29R8OXTayt9k Pxr91mbryMMgk9H5Va8tbYht89X9hbkY3rdVmvV0zsNTm3KMweownQxXoMUHTZ/SdrmseBuP1k6E qHPve27UgpwVFBuqLrO8q/4ur8v9K+XZZY8fgmRx2CN5xJEWRp9so0UbGNEBxTgxFSJhGdXA01iC jU2hGkwTZKBF1nXqNWNQiSim6AlDKrbo4oswVhEEACH5BAUGACAALHYACwCUABIAAAb/wIJwSCwa jZTLcclsajYeSnNKrVqvyI12K8UKoV6vp6OcXijosvGx3agp7Xa30PHYjZdNZ1PYdDVzU1BxgVdg YVYUHlUafWd9R4pQdh4PBXBadlxCdXt1WV8dnIVMh4hEpqdNilSWfQ8aFw+krEOfRB58RLVCtLpa s49VqarEqpGLU10dFLGXSMm90UK5RbxLcJxsZ6RLxojfx7vT2JwXos/W04qB1UQPHmqRuotuaFZQ aPquz/q0+sTyACsCy0+RLY10nculRqDBdHw6WKI17UIlXLqI1JG3phc4SpQyxgPZSAg8SnumddiT SY2GXPmGjNliUchCN9JgRvlSwBUb/mT6LKKTmRGVnW7i+pDDNdTULWrRUll05U5YKlPX3BWY2hNQ Gn7jSBrRSrBO0aRflsp8kwxeoJcyC7l7uvZdNF4WuaHxULLKtSN3mCjqi1Ypk53SEo9TbHQIFDJx i9yNCpISR8eUuvwdq7Zx4bSH59T6O3ppKgp1SiKWiQvzFX9DNkvuPKTmZ8NLVteCBxYuNY5kQRcg a5tabHKyXtOGWkSYzeUfQx+XOfTkkJdzns5Fh90k3Wljal9MBD2wa5PBk04CKVL0ZJB0X4KcYzHz 9fngi9SxjEU2rqWVQXebFQJ1M8s9SHSDBliCLThgEwJd9uCEFFZo4YUYZqjhFUEAACH5BAUkACAA LHAACgCMABEAAAb/wIJwSCwai5Sjcql8UJLMqHRKrQopnqwWavVwrdKOp/NgUi7nL3Ez3migF63c I3zIjWknlFKeYjeAgH1damBLHhtRFw9ofBdHYxpsXgUUgW2AQllPYkaJBRsdQh2FSliGRpSoUapL j4kXG4+pn6B0RK2VHrMFg0Ofsk9vVKerQ7nGqaVDUIiylbRDdr65xUvAoG/LeLfJyMm425VliaLQ RYjh6ri1R9huT8TOgX1PlplEsZm5+hpGsbwq0Yv3gE2HWvo2wAEF6gykWhq6aVLzB9ySP4E29AkV 6CCzeRG5sLm0x9mYYwcz9jIIDBOleFdKZQGUJWCBb7bMWSRirQgb3Gnd0l1RFTHfrZ+9+nQ6VkuV HV4dzDE64wuXM3/KlizdOVQJPk1d153E5Q+LzV1rmkKJmDFLFaFKcDLlGtZTu1s9bzY7+8kO3Fxf VY3M2M6qW02F0YlDyjXvr7t1J2o6G/BCh1mA1QphbAgupMUSLTreDHnyRyicrdW75XGuZF1cNOiU 4jnrr9kesDaeI7h0gTho4rTaRCHiLDZnhGLR1uaYyF3JxaFLvO6YydA77dmT5usLBTGiFq3JQoqI 7NxFxHh5MEj8EOFoq/Axc+SeTbr48+vfz7+///9cBQEAIfkEBQYAIAAscQALAHwADgAABv/AjnAI KhqPyGMnyWw6ixtQ9AmiVJ9LzUU57Bq91KNmPA4zl+a0UqPGbi4adJEspYOEULmRDdJM21iAanpN VnwaVkkdfH2EhGaHRluCipRmj02LV2eMZ4KRWpaVooGQVJpOmJ1JoJNkZUh2RhR0hLShrKywe3Wz snN9qYyTSp6fr7y/YlqOZYS7Rht0kdLAwYBCY5iYwX+icYLErI8bz19pVolni7hI3HmkfaupX95F 4knq1neS8tptqDKdmtcGWqki+u4wyuJklxw2rwxiIXjuCbhvFEeho7Jwz7swAY01/BhG4qwmF081 rMgE38CD+/phTJUOzxc0WxJSCDmJYZEbR+mwZeTnjiHJeD9TPdrSAV+5ozttIi05NEkQACH5BAUG ACAALHAACgB9AA8AAAaNQJBwSCwai4+jcslsOp9QaBIZrVqvTg1og+16v+BwsSPmis/otHq9ngq1 IDd7TrfKzfI6Ns/mD8l6S0lwZ2ZbhG9KhFpTbh2GRYiARFyMgZcgHYhNk2kbkJh9Vp1ZoaZ1pFGp p6yZRqmgRJuttIWzR0l3dZCrtW+pD52xQ7d6xW1cw3AbecNDfmLQz2dBACH5BAUGACAALHEACgB9 AA8AAAb/QJBwSCwaj8ikcqhYOp/QKGhDrUqHm2tU09E0tcRL9kKkVM9ZkOJ8pKiLis5lPv9K0+Dl hqykKNxqgEUbGiBiHUN0IBqKU2kaeIlCF4VDiHlYmHpQZBR8RnuJkVNGHYJ2koaCIJeao5qDUHuf oJ9xqK+tSHxkn7p5r7CZS020R6GWsUVySryGlnR1RY1hc6TTxkKeq4bSQgpkjNWfbr0g3ELIQr/B 6lFy0V+91rTwZJFidJHwy4zRauF4IZrzS8+sDaaUGbnQRUrBSXjihCGiS5cgMd++QKL4KWJCI3ZQ EaFi7ZiSjVAedqOYbCSWSkc+tkzUkaM+lceyuVTiTonKc5LrZqYTmo7PmmdBqw17Fg3osg5Qsehc uitYzF31iEZCxzUpzaUYgU0d2sxqKawsvXoNO9MOnno1tUbpqRBiHqh4WzltZQZLJCozO+ocQ5Uh UT1jr42c1cFsFAUiQWlDJcbqK0hZIA/xM4gKOmJg5nxOEgQAIfkEBQYAIAAscAAKAH4ADwAABv9A kHBILBqPyKSy+Hgsn9CoVEOtSoka5zV6AXWVznCSCqJoQdW0Zpg2iptC8faYnUPXUThSc6GgQXIg G19MDxd4SF9ZZ3ZsjI10j42IQpRojJJLTWaZc3WQY51Flkako5hznKJXn6CRU2NuWI8bW6pJek+t RH5buYNImZ2UFLWzrkOriJQPxmW7poJCG4jAR9ZshcmZZH+looRQq0nOgOZl5dJJ4eqVw8xK3b2n 61fjUmfsG36Z6fRlo1gt2QXqnqx/dLCkE9XKH6x446IdtHdEiz9/8PYY1DUwYh475QIx8/cAj6Vy BIdQkFiqY8Ah+z4ywfeH0aJiRDZI2tekm7senOZ0PgxFzleTo7hG+VRqaaWGeUIOsWSzFFnSOUEA ACH5BAUGACAALHEACgB9AA8AAAb/QJBwSCwaj8ikclhYOp/QKOhCrUqHl6t0A2oqH+AHkkKlFKvo S2GNTnqZG4pc/o5mtc+LefmuE+9kXEJzGiBzQhqFQndEe3tTIIJ4WJNOjElijmJGekNkZ0aSXUaO RaKTl5VHqUl6FJucFGtrG7NsoUulj6d4rKp/TmtmvouPkaCkSrpDcXOyRYdED4ep08aNpHRMFIWP 1tdm13/iwEYa5EvNc7Nkc52N7o2u3NDcqc6yBfSOG668SmUCcRrzT0lBbrYknSNSENEgDbaGKPJE SUgBUVRmhfGDxRUSYhKjHDQm6dTEiSGF/INl6NEldQKhvPu4ZOGTkQyZIYvEckq+dQIXbB6DV9HQ OXxINiiVNHNVLpCmxpDUSeSkuSIPGJ2SU5QeKnSLnkLBSVUIS0mfkLy509RQ0aFvl7TdOegSynRL lXqaKjFM0KqXNnEDI3RimbdmwlyZW67qURB38awBSMWiLTKVz/iqPJmJrayZpXB8wlVKEAAh+QQF BgAgACxwAAoAfQAPAAAG9kCQcEgsGouKo3LJbDqfUGgSGa1ahxQN5arcEh/cIfioDZvPRvAYtC56 QRrj5S28XIT0o3cbR/v/bIBCGm1MbX2CiU5TVE2IS49VkYqUjXhCjJBOd1yTRJl/ap9Lc02FhUqc TAqqkktvea1MF1OsdW+lR7mDXhqgUYTAeY6kRIiyj60PqrIgFK3NQ8F4w5XO0UqeZJiRzLHShdjb xta6wFCI2nCb5FDiRRrx6uXrT+lFzOGFFGPz+PSC/EkbgmwWk29HFPgiUk0QnXfw5MXTJGQZEWgX M4JQZQuLwToA7dSB6EfBli2o8ICq5gVUyopVflk68vJIEAAh+QQFBgAgACxvAAgAsQAUAAAG/0CQ cEgsGo/IpHLJbDqf0KciSq1ar9islvnYekGFr1ExHT664nSW7C1Q3vBwlFJWX8bFqT75PtfhgBRD gHh6ZXVXaE6IYxdnj1V0aiAUiktsSIJnFBd6j5pnQm9sgkVoloxUqUqrQwp3WZJqskunmYoPpYOI r7VCXWQPrU6WTcMgvbFbZJiUrkqVQ3LIZNFDsApdtMh3zKuYfozN3kjFrs1C2USPU12wIMXAeaaC x+imdZj1ROC28GDUBhXptsuXmXXw2GSrI+/XkVTqDrpSFDGiI3NC5OBq1yVXRIQOQx4MBS6JsH8o QYpCaGkbPF2mjKCaGbOmSonpzDDiFOpIz/90Ct6gpPNnUJgHbjbJDOXv1LsLBRrK26mJE0xKvNq9 w6nyXrw8qcyhMmMOVkciuh7c+doJnsec0XIxsebsWkCcaR/9ZFpkWzFdrSgy+nrz2TzDv07azYcs pVpkBRzBbafJYalkfW2mlfxybU6daG2KQvTXn8xzolN+PsyvdZ6TvXC5pSj51VmsQghSg9nnGsyf aa1BYqPogvF3dFXj5voSqE/UhS1hVK46MDfFyIT9BFF7LRpav5dcuKoo+F2dvFqm3vaxuciug0VP F+v6tO2Y29s6g63/SXhR5UkDFXETnSZQYfs49AdFhDkXHWJjSMcadsAcd5w6+YUmCnhE/VVQBhpu OFPKd5mNBiF6YWWmXnTBFOOVTdM1ppc460ACFDlIIBLGVWgJMs0/yW0ozDFwpPHjiZPcU98kTDbp JJP2PCnllFSqcUyVWGap5ZJRBAEAIfkEBQYAIAAsbwAIALIAFQAABv9AkHBILBqPyKRyyWw6n9Dn 4xGtWq/YrHbLpHC/4GShQKR4w2jt9KlgTt/U6oOcflDiQgVeOO4j4Qp0enBvQ3BGBYEgY3xbZ01r SgWPWHNpIHtIbYFkbUZTbXZkdEKZU2ORf6WkVqlumYiUV5Z1rEekbbalRaask55MnIpYFMCvSnOy RFSwRcbIyIe8a5G0zCDA0mWlXrR8xYCfeJzYoaClhUYKlHrYb9l2D55md21ej7Lde5ln+/5Jdwgt qxZHlh1PAo+c8yZE3xRK+kCcYRTvDTiLsFw9HLIOYbxQ/bqZQTKSn7c7kzgaObNp2xBGSEglKlZm kzJjlBhKxHTkThH/n9yW0Qz6k9dQopjwAC0KKemuVdSWYTKoCmBQL3SwOjVkyIsxhpGWYrv5SGO+ aUZXehwy8ueZe3l48oSLbx0ZmvL02AuV5WJSO4vc0mO3cxmrpalcsTW076zLgeLQlakXOerkNSWZ 3W3I+eXRzlyPrBNaOJVYuaBXlfknsRlQs0wlo52tWA/QrIsNmgm0Gy8ZKq9NxZ4FPHfZ4ZgOC98a G/bjwml/rlVH8y6eikTsLbrTVufiIgXkcb6ehJnJxlKV8mIFWOrYT2XRPx4NfyVjlWypTDraUSFH n5Pokloer0EXl31rtDOVWrx819UeFzSzYFeQUfiYeOJAdJ1ScdCXadJgKSlhWyCnxDXHTFyFaN+A u5gxSmg/pfPcVMrU9KAdBsnnYI1ODcbaWPTgMYofThTyjDZ5nOMeatiA9w4kij0R3oHOSCiFhFFe ouWWXNZRnpVdhinmmJWASeaZaKZZoZpstqnmM1EEAQAh+QQFBgAgACxvAAgAsgAVAAAG/8CCcEgs Go/IpHLJbDqf0CflEa1ar9isdsu8cL9gKSVM3lLGTQV1qWi7rYrycD1HR9tGtz4u1MuRXk4Pdkl0 WHxliFqIanl5jGlag0+TS4ZXimGZh0WZm5d/RVOUhEZUdJkPjUSpU5usoERns3yjg2NnQqi6dLNn imO3BZ+3Z5e+qkQPp8ZCvkeVusGzdLfLzhcXo1N0gbpeuUOjQ9rRBeHOpbLcwufU6fBzF2vGy9pD CvPcw0YU5bd8rN3y5o6dvmXtZBmy1mbQGoHnLrTx547ePXgPvOWz04xgNiISkVA8ko1QOHMnCWV8 eLFPp5aijvUi6K8aQSE3V66rQ87Omv95OEcWuAjUXdFf7rBpi5NrDR6csYYSFEZlXNJzhhRQ1FrU 5c4Cl8xJE6eSYD5gpcRiHRtv5yRbISsOvSqRGVhuY7RS2SQU7Fe/uRqiyUgum2HDfW5m6srPWayj ZVnFxWlK3TiU5eQlzYVu6DJcoBsbCyRxJKi+onwmbRQS3VI3y/jk61SEMSKrIOlFxjdZrdrLaf3Z meeNOFpbU0bVmpUO3VNsSZxfhecto1VFs1mlpj0d5HJlZifjZquQPHiLHGGCvWgPDaJssrNdQqTz iPTOQzt31upe8Xbtd1VGFniSBaTOellVpxo5FtkECnsb6SIOTTmNw19Afk1XlXvYLDaGk1OKOdfS G935c9tuidUSizXS+DTcYHGthNA59rFCQRzPDXLbLjXhI9wZF3VGlY95+DJiiGVpY9hMvqBFIG84 HhigPyUp42JJUkKhyivDPIfPKw5dkwSJTCDEZZnNmCLmFfjx1GUaZ4Yi55x0ZqkWnXjmqecVd+7p 55+AuhnooITqucoVQQAAIfkEBQYAIAAsbwAHALIAFgAABv/AgnBILBqPyKRyyWw6n1CoIkqtWq/Y rJZ5oWy/4Oc0TM4qNOW0+nJRu6EUb/PxeNuR8bseqRkzKW17goOEgE+GhImKa3VOiHhFjUMUD3JD kkJ0dEqVSoBslJl1gF55BZaXkp9dRV6VgUevoK2kmAWbn3JsrEYPsLeluZOgjRcaGqwXmGiXaKZC ykQadL/PBbxHoHFs0KQUU9zXqAXT0F3bsA/T53jn242+cehE2nEa8tvj4kSfmqRCueoYo0Ohz7OC lgz5agYLUZ8h4QqcsQXxFz1s1wItHJbpgh8FvNRZjFQu2zhsxuiVPMVsyJlWK081hHXvkpCWu4aU jCYTpxz/U754PioyEUlEcxAt8cIoM1NMI0P5jdyYkV/LWzGtNS0iFNbRbrfaRHtkyqCXM2M2ngvE dNJVridndtR5rG5dp0tqmjyys9pVdcugjuT1COQ9SQtZGcLorM3CocrU3aTz1moSpkfLYTusSRNe JXqNtCWnyy8RwBxbDf5pERAynZInv+3CUxlPgPJwa7VsNC6/b1dHf76sDzffYqabSbqdml6jqE6f v4Y2naHbkcfgZQddfN/FIshQRQVaWXU7wRV5R58LNWbsraekyUG9Hjyq0OnzN5eJqZhvlZickZBe 702CClPI+VHQcsnVN1o/HSUUiIAArWTRSKf4kWEv4o1TW5CGBe0SDmYWUXWJiKEViNRFu6wU4i6Y HFXQaeWYKJVhx4iXjjHhLZKEAvJQdIU8GkJRyW5AhjJkd4jQUWQsQvoo5ZTQJAEdlVhmmcWVWnbp ZRNcfinmmKlgEQQAIfkEBQYAIAAsbwAHALIAFgAABv9AkHBILBqPyKRyyWw6n1DoI0qtWq/YrHbL 7XpB06/4+tiMz2KNBs12Xi5PSnt+hNPvxU0Yz+/7/4CBgksacoNFFIlddiCGIGtMik8XkEcUjHVI kkiYQxSVjUOdQ2uGG6eQoCBmRGadqhuJqkUao0OsS3tCtXmOlbCPS7irRLxCG6rGxIyzSGqttKHE IBd61NCit9jaq3unQ2VKzcdJFMPBjdZC4bfjt4698dzv2+vnq/DTRhujuGuVsXZl82eH0adCpJCw c6ZkmD8jlOglicgQ0TBg9aj125dv1z2A+obZ0WOnjDeB6O5ljALJ3K1TMGHOQ6JSWMM8OLE80MDP 0ae1IxghsQIllJy+IzWdqOR3sylSmk6NpnEY8mgwhI/M5XtTkGtUKm8WWt1nk5OtpFapPpVXLiC1 c/fMObz37WXZK66IUISqpFoSle7SehpHt4lDn25bYWJKi2hgqUI63rWXE7KQN4qdadCFVjBKoKBq lmF0MRpEXRd0RWZSTTWyY4+V/mNs+dE5nh7hDe3seSyRMjBtReZZ99BvNqrjJEleBXMT5sajS59O vbr169iza98eSPKTIAAh+QQFBgAgACxuAAcAswAVAAAG/0CQcEgsGo/IpHLJbDqfUKgiSq1ar9is 1qm5bL/gsHjM7JDP5M0GzW673/A40uy8aOT4/Nv+5Ov/gGBrfXdJCl5KXhdTUQqMQ4hHhxqURxcb il6Hj5aUXUSHIBQgG5xFnoWnXaNGk6mopkKDkEKeQ5OYQlMdHbMbrEJ0QhQdh5GkwCB0syAXx8xH Xc6VIF3StYXQCsIamM4bqcqkx0WZzkQU4M6XzN3rF3TruafH7Mm6dvMadPtCfs0dIlW61yHcEGFH EJ7SVssINSOXnPRaorAcxCH7HvWDVKyIQngWIaUqOITVtiHgZgn7hbEjKSKR1ECCRqTDPYzQHl4c Z0Tlkv9uSWguhKmw4s4k/9TEGgTsph8zn8QNQymLCUgkUTGmimiEl9evBymSwzhWGSudV8PecinS IaJ/pEgWWfOJzzwQJyOy4iprFB0zxJAarUVOJ79Ig9UmCYg0ISK0RWEabDY5KlxZcoMRm7JtM5E1 vjo5pJgkK7ZTyjiVVdw4miRu4dIGK+J0yWXWyl5lZi1bF6+aifEyjlY43LbJNBGL4QvZ42dLNj0y uh0sUuCaCUEZlYmSZuzSxU9VLKpcSaxH3P0hbI69qiU1rEZF+odQITSho62MB9dtkOlqlSGRUmRz FaGAGpRsgBA8CToUG4GJFOJVOeEoaAY5psSCl4HLOXMkExMaGrNaHZpY8uEW1IEYyIosOqQhZS3G KCMYKc5o440RYhEEACH5BAUGACAALG8ACABlASIAAAb/QJBwSCwaj8ikcslsOp/Q5yZKrVqv2Kx2 y+16v+CweEwum89obaeTbgs1GifFTa/b7/RLHM8nTvuAgYKDhGV/ToeFiouMjYpsUImOk5RLc0WX RJmYSptIG6AamZ5RoJJEGpCfphdFF6BLoK0gpqdCqkSvsn64qrOVwIS4SXtaxUYdh7C0zEPLHcdF kodzl7/IRB2ZyUNrvMd63Ue2bBQUFx2/G6pT5rbB8HjvtH+qc4foR96an8PO6X4ODVM1cNYcf/yS +MM1rQtDP/EiLkqGUJUGSXuO7btVZZ00gb8QDkklhJSRefmwCZlXEsQmOCqzQbwlUqJNN7PYQEq5 cmbM/wshr0k5mYigHCwsV7KsxuRUoqLNbkqto6xJRZcJrTiVdK+IKHNgL5l8UtPZUqzOxp30KWRW 0qlwcRr1twEmCDh1kwiVRhTVqbJjZX6KNuTSMiRMOer7+TauYzBxqpIrIlJsy459pR0jmaswE85G eAqm1wktiLJZe7Z9zDpQNMKnsw17RdnkVr6kfl0zafdWtG1GMh0+khjEXnHI045cHbi1cywIo727 BtRraKX7bms6RYHNn2ImN3YbHnDNJvKcqtWcYpEvctTP48tHc/x4lN5rXTYvvH9+/HNAXfCAf5Sw 1BiBCCKhgQcemNKBB/AluMiBEkr4wIO/eVBhPBRu6HWfAgweN6CHlfRHIoIbNHjiiixK9QCDJrYo 44yAXMAgjTjmWEiKEero449i8AjkkESaIWSRSCbJxZFKNukkFDZ6oMCTVFaJxIse2GfllkoyyeWX TYKoohEjgmlmjhdCmMkDC57pZo7oMLgGhFq+aaeHD1BQZhAAIfkEBQYAIAAsbgAHAGYBIwAABv9A kHBILBqPyKRyyWw6n1DoI0qtWq/YrHbL7Xq/YG9HEy6bz+i0es1ugzzuuHxOr9vvm83zcu/7/4BI eoFdcE4aHYSKi4yNjohPkI6TlJWWZ3yHiZecjg9kSmQaU0kXpkUPpEOgR58dr4MgmYiiZJ+qQqdC iK+sIJ9CerhEfK+bRmNGpq7Hxr/KRResr0PMGnwPHtrHnd2AhkMeDxu+3G+m3BrlsUYeY+rUIGPv QvEg7NmZvfDccMlIGjyoUwduFcEiicgdVCgKmS9J4YRYKwauoLeLbR4KJLKpoDsihjx6TGLumTyL 8S4UZKWyyMglHjK18/VmmrghHWKuugmySED/mSACrjpmEaPRNtk4ggQaLCepDoPI5ZoaVElRnMiI ggT1bwg7nUpKKmlZL51Fi3l8FgUL8c2wo3DRaK24KmLVNz3l1RNydVdfeTTtsayorXBhu0k2Huma V55Zl0SyDWtbDxRlOEzjav5yIVEySF2TSoJDma9pvAD/Mnact6sHdu1g0gw3u2ZZIkIbBy1Z+l/v j5uDf4FzMynPvbKGqARKJu09PbAhI1lt77lb2lZlJ4me9PZO6afVtpsldrnw81s2AD9pTiW4gBaz iVSSrTZghNyyQSUS/S7q7X8VVc5jjWXmVzuklMaXfeg16ARYskAYTizZRCcWMrhZpE9g5uQU/9tW iHlF4WuRYZUhRwQiduFlrEBEYngOxgjFhUX0B80S6rVjDDjUlSSWO6+8CGOID+S0o0wBUYNSiuH1 BYlh7EDER2EMymilEcO8ZVI1XwxUhZafqHOFNLYcUWUTzhmhIBNaXskJBaYso0QBdNbppiMdtLnm nejBl8cGRvKh0iZ11qnAf3xasmeimhWp2BAUfDRooeAxWsmilhqlgDYGPsBHpBvY6dJfmRJiYKlH qWcjpHDQeYQ2qMYqqxvyUbAEqK62Q+qsvPaKhXtM4IoErL4WaywW6tHIagcUNOtss8AeK+20aK6X RKRlGbPjrtR2a2yywb5WwLDcemvurODeKlwuuee2O617hyqB67i6umtvsfKdymqo9I5677+8pntt q/2CVC7ACDu4qZCRfSpurgYnLLGljjJbTUB6TEqpEAtP7HGinW0TqBAUOFconQqk+fHKVz5AQZtF iApCEAAh+QQFBgAgACxvAAcAZQEjAAAG/0CQcEgsGo/IpHLJbDqfUCglSq1ar9isdsvter/gsHhM LpvPaO00zQat2/C4fE5Xejz1vH7P7/v/ZW+Ag4SFhoeIiYqLjHl4jZCRhBtMlBuUTZhLj0gdSh0d mk+eR5xCmKRGppKsdKtJok6XXZSCIK9gmLEeqbdFuEMesUnAQrietq3KYRu9Rc5NyULSRMVRpm/J 1nDURcNE0MviZni420Oad+jA3cZd50PhwX/w4/ZmzUMUoW79c/X3jFC4Iy+gQSyW0FX6RefbwYcQ 63DCle9ZmQ7JHD5xWDCix4+JXmncAlAVyJOSTKlTMtJKO5JvWmJZ9e0lypulkAjCeKVdSf8uJdOR sRnsjjCcSPkQ7QlmaRenSfdQuED1woMCWLNq3cpV6wMFUcOKZaPhzqVmvC6AuMCrawEFdyh07aCB 69i7eLM86OBBQ5GBnth2cFvgztWtD+7Yzcu4MRO4HtQaeaB24AbChrluiLvVsefPRDa3HAgCaykP h7MmFt0ZtGvGiT28tGxaFeqtszJnfc37LttztJHoziobxOa6u3srT7q54zReFKJLj/5bgdYLgwvc 8qB1ufebzZmQBgGqfPk71nfLNS07+ff3EcMvCX46fYGBGvJr4JtdO/z/B8mnBH22pQbKWZfoBuCC 91Q3nzC1/XJbAYmBRURZl/nH4IatxCZpWRK0aVjNhBUREVuEHKYIiYA64YFiUQ+AAJY0fF0gooo4 JgLZN5S5AaFbhoHg141CCEZkjkgSshd0QzyA4VptdQVZjBAKV1ySWB6CHUH8SUbBJW4pcMkD+1yF hF9+ZammIWTGyIR7UAQBACH5BAUGACAALG8ACABlASIAAAb/QJBwSCwaj8ikcslsOp/Qp2cTrVqv 2Kx2y+16vyDKBUwum8/otHrNbru3nY70Ta/b728xfk+kePiAgYKDhGkbf05+hYuMjY5GD49JipKV lkWIQ1REHhcdFEQaRR0bG6JDFKBDGnJIFx6wsKcbF34ecrBCHqpDpEK2sbyKh0odsbeRvbEdY5q0 y2HHvEyiskIFubkFQ1OX3oXNIJHJIGPbrbrh5JkgcZyTIBupFJsgU50U27lC6GH+9mFSAQwlbxoR ObX0DBlTkF45br8Expk3kFO9eH+aiRJVgIIogVREhfxGko+GTHLQsVtY8WKzZMnGkMNkZFtFbuzI oaNiE8S2/4tLxhgkApSYLp9JhC4BaoTSUSHhSkqls41cvUi8mnVTxa7Vpk39ikQ1stIeO5e6Ps2j EHboOyjbtJ5l4o7oEqcIp+rFQyUcw1B/xrV7OPNpWSNMLWLKFO6Ul8QYkbTaJwTy0rLdog2x6cHx 3s9r/nQGcdKe46r9HoQtF/XC2CKW7QGlDNV0kQK4c/dsAtmYZF1zlRglinmTU5qgkxtC+hPpQdhG TrKjjaQwt9krOznnp2U11LLbTtGOXRu6kuOoBitfD+i1c5hCrG9WTxY7EX10DyuRH8kz2eBR9DUJ O9Pox96BVwjzTxK7RWEMOX/9Mpl9kNxHX15JUKZPVs2Mgf8OhmbZlaF/lWVUHiqI4OcPeQi26EVh 8lEjTh9m/eHVWKUUIZ8+ubh3UD+c5aIgdZWhVcVw3KGYXi8uNnlFgw1ec9sXHaUSJRNXVpnPFQ/M A2WXMTpRF2IGnuekHWK4dkGYurV5xAMKHBHnA3TCeeWZjxiIJJ6MSFfKBsYwU84tPrVZgAKw5ONm B6e0acwtjwr6S5l8OrJnpYKoNlofhL7SQW5TevAAqPFpmJsxzSgwxqboYVrJpa7ugah2kAg1BW5H wDIqriXucg2uxqiCmy1xthrrschacQh5fmxwp66kPnDPJqAGWyhu0Bqb7LbcVpfoXfE8KyqpOep6 bTu+4qr/D1aUdutusq+0C4pl0PLq6yEc4XoIKLjOO+m7AAd8iHdFqLLWWvEqoJsnuMLS5r64qXpL nJoFbDG3AzMBCqRxdBwHLAqDquiGoGYc6AUit3vxyi1mDC69HoTcUWca1BxoyZ1I56a2LPfcMqEv ZzgubnH8WUq9GG15S5s8++y0cgm/LO6u0lK8yq0/7XJON7k1/fTXeklLKzzOIoH0amID66s4sKA8 rMpgx+2NywOWneu4iLqF0Dli1eu13IBbMmtiD9jq7JXQlnaEh3xPc0jMMwcuediB8vLASX0tTapP cY4b7hE2gYLqYp/+PfnpjHgCy8eS0sOToQqUEkkHMRawE1EBpRjElloEo+77I2BiyesZQQAAIfkE BQYAIAAsiAEYAEwAHwAABv/AgnBIuRgvj6FyyWw+FE3oY/psWgtQhVar1Hg8m3DH07kULmSr4ktp djTub2dMNgspaebjy/8KH2NwSngdZ3lNX0lLex5xdgpoHoKEUWwPFJhYX3aLZngbV4lMG2xMY21E X1CUiB5QSqSgVwWfoR6KQ3uxph6oQ6KsTKK5pbO1VsNDYQXJQqdLwGDIt0qRs3fS07hCvQWkgsrd qbLHwq6wh1eEmOzska9CF4W0fuiokGSv5dC9l5ik84zJmUOQoColHXw9C2ewzKBs5vqASWdlHz94 eDRo1DAmoDcPF7w0WmLxFzUhCgBeoyerFa45YWImI9VG5cOWF6sdFIiTn6LjPfCEeGlJ0xlEltqU MOJU8ahPIRs8/qlXYOHScUnRSWVS0mSSNb4QgjTqK5KirsxODlnj9I+ntl4LeLGCZt5CqAeD8XPS 0deDoYa2ohQFl1u3MUzTFsID0oiGZWk3Qo5HZ06dO5OXpNxwqcO2JY/hhAlLaw6mggWxoJ7jhMLn lbBjy55Nu7bt27hz697Nu7fv31c0kL4Ttifw3nAhrjl+/A3XMUpGMvftHPQaTtKn83aoFA6aX9qp Jw6jUVz28Lm5/+E8JSo39NuZauAElBn83WAUUJEq7fz92qE9VsQSF4CyQRAAIfkEBQYAIAAseAEI AFwAMAAABv/AgnBILBqPyKRyyUw+KM2odEqdbjqXR3XL7S43Ho93TO5exOW0es1uu9/wuHxOr9vv +Lx+z+/7/4CBgoNuFBeHWWUPCkeMD4+LU4wKlJVFholJGmEbnR0eWAVnHUgKYVBGHRpHn6CtoUIU oEcPYba2WqKgV6C5RA+fq0SypKNJYb5DtWhFnxdCCmcewsSNp08UhrEez0JnRqbctM+yG8ceyUJg HqhEn+0Fsh6M1UdhjEazXx7mSuXn6WqB6eeOXRFk8fTlQ2dE4JJl8I78Q4KQSKcCFYe8O8hw4sJ0 BZYtkcbE48eDUMAIGwIG3kSTRO7Z4weSpcIkxLLp1CkNnzf/UgmZqTNYIBoofDCHXNOZSxrNI2CA +gvToapVqzI1tttoEyusbQQ53po2hEKrpxZvIkmqdF7ZaRrifpJaAMyFTULBUmQIzciFs8miluQH UGOHTogztqyrli1Gt0vkhe0ZmfDeXLV8CtlEcHGBT2EdZ5wqdFk3nJZn5rrSMIxGoqbfho3Jl4nr tHQlpj5pKqIQZ7+J6uIrujYRzULUhpst5AG53Ry1bEJi7LNwxm7rLZQ4+8xpZXPbPeCsK/eQcFqg 04YCnDYpeYg0XHwcV34noxuaqh/yl+rcbhTMB04nT3RQ02YbrNJJRGZ1kM1VVxUFoVXS2VLVd05Q cCAhSkDCluGHIIYo4ohFaOBbPPAkGNd3d9WHYYj7pdZbQsJcgZmAIqpihFlCEQWGLvmsFKKOJZpy Gl86qjfdiF81t8o3yW3wlzDiFAFljhh2EhdR7BT4TJVEXDnkdw/k9whrGOmHEXNLYkmEBqdllqY3 YrSplJAg8qMAJLkRZpAswhyWiwI4hihfXBtoE6Y5Wkq5KKIvkugFJUQEAQAh+QQFBgAgACxpAQUA awAzAAAG/8CCcEgsGo/IpHLJbC4VlE5n46xar9js8HHxeDrasHjspGy8aLJ6zXxQkmY0msqu24eb zuWxvXTkHhtvd4R2Z4CAHYOFjGxdiF8XjZN2F3lTGouUm4V7nJ91FIF7Cnygp1micqisVwqHHq2y VVx0s7e4ubq7vL2+v8DBoRfEnmQPCkfJD8zIVskK0dJFFMSmSNHN10YaXhvff3oFXWDKXppDHRpH f1/t4kKi5UUPkB6m5Hlf20OPUu0bkm35s46IvHFfknjhV6BeLCN/JBVQ8KjgQSMKzrmhUC2eB4kI kZDbckhgxo9HuBQQZcvIQiOH0BX4o0lVsosuPQgskrAJy/8iEYWcaXnkJ5KXROoNhegB3UucPO8Z UVqm55BuVBzKpBZIoVQi3wogTdc0Kh+jORk6rDpPSLd1j5igTcvzzZmCeMoOMTqXiJedfgMxNAJV rNQzbZHI48iY8SPAfjw+zDuI4heBfYdoZIxvzuC9XeMFLYBYrpd/qKX8JaKIrCbEquF5JKoZEd4o nhV7+7fhWuklmWvvFKWhuIZwYD92mwyatpCxgIX4QTN4sReQQq3CCX1krJRv4Meesat9Jfeo0Yt6 U09FlabHwM+bFVIvOlbKQv60DG74M1fmoJWz3E4OYceeV6bkMZUXrtF3XXNHfcUEg4RZ9Vt2iVXo 3HNSZbT/1Wg09YMUf2MRkV55HrW1nhAnOacSf/0V0I1IPYWYl07mZchhUUR1YWCKBj1IXziLPHDf SOZIJV9gb4xWGxiqFKNBWIYZB55lvUm3pJaJLffeO+FIZMaGr/QWhX9TrvMNOlEo0mZqYCgApxR8 LOfOj3tRCZaeSVHgnzBJMQPooIQWauihk2RS1GvGYXeBcRqAZElxWRJhDKBbcueheQXlYcoDVCqo QDeAeYCXMOoQ9odfg5wREk9q2qLXSqsOmmoRGmQE0lepLjkjlaL4timgstEH12Sj3IpSEV3IqIcl i3R0nK0GflOcXk25Ic6ylsYSXhHWukosdqA2o6BYnYlFRtuvVEhBUjM69lJspFvg+FWzM8JKGhUZ dRrtoIGUwkxiXZVFXH6VlilUOaJQICeiaU7ZkaVUhOvoBpRKipfEeCKaRTRZBAEAIfkEBQYAIAAs WQEFAHsAMwAABv/AgnBILBqPyKRyyWwuFZROZ0NxWq/YrDb7uHg8nep2TC6biZTNd/29nN9w8kN8 TLO/G83lQqEbHxtxgoMFGx0XD0NdHXdURoYUCkNQah6El2+Vd2xhSYxgUneYo2Vem2BuS6anpK1j F4ZTGn5Jdqe0rrlbiEi2bBt8fbrDYxQewA8Kcxqfa53E0GXGp8640ddYCpqcqdjeY10b4rzf5ebn 6Onq6+zt7u/w8UYUe3uJZslHkg/8+VaSCgIKLEKPHJKA/e4ddKIBjzhGhwp46XDwi7UOGo58CoVq iDGKf6jdm2gIjEIipqR82iBJiJqMagIlecAoIxowEnEi+XJSyIP/Lxo9pFJgyuZHfRbn9EllrJsX JBMVVWr5ssC0lkYUtDnSxeqxJDwfWTTCyM9VryCNfMFKRCcTYzKHMErVMNVcJDGXwAXroefPvEXK Fgl79EjYIn+dFB7SUGZdIVFDerB2M67avkXEFTgsd/JgzHsNY0YMtMliIQ1tPi6gdTTK0kpCi+7p uSoRNWa/erXc1gPbIXh61nEr5PDqQh5selSTthaYPtChm2J7AeS0zJ5ZT2wp+zMFpd8hr9kgvLLH u6iFeoQtZArxXl9UyufI9lkBwUOYh4q4njfwTcpFMV55Xh2jEnlEHHdfdqwd895w/v2HlTEaVMgM cWpc0JAlBOl2/5lCv0nUTHkfTdMNY+oN4UVcjT04j4cfyjWFOOJwhhtyze22k29v4QFhgbQo2FpL yU2nF4yf3fPTb43llx0jlnXXG4EdctghSBuypSByGRnDz1axITmlSzkW8JOV+J3ZjZT/UfnZcGkx l2CK61liiEsumrdjIlpdlCJ+OY3GZnGuERGii6f5mN6JhHohRmsRdjUooYk0BJVOgCLH42m91cGb F4wKcZqJixqxoZVmQkTHA01GllVYYv5XBXr/UWTiHhpotllyFdJI1DEjxZpTjhtWYRsRZyqn4kYQ MaVrVuLM0QGVucLkCBpS9DGfSqxtK0WlzvDnqX80SgTMEblSOf6Hm/L0I8+78MYr77z0bjFLHX7k UeGJGlrolL4IopRIGr3mKka/FVKWTqwe9umVTYYoqeudCjTEVnKsfafGuvcFTFM8GM3DSFtiqJGT WtYCR4eACcaZY4jrhFyEBlp1M1rIYlqqq5f5OUwmcKGCzCirJxcHjMx0qmgJM3tca5UbzOQH0k8K uyOuS/pmN5m0biQtXiE1ZpbHxj97VXU7VwPSz52bBbuZfzoHIoVU/UxRds3zXq2HIjyO9pSlg6Ws FcQrc8h2IS/Hc4wy/OT4lWcUthewNjKxbUwkjsOUlgIYtfQxPNUazCgsYOfKL8BOKSd6ERpKpGwB oZ9bbzYwmwOBVRAAIfkEBQYAIAAsSQEFAIsAMwAABv/AgnBILBqPyKRyyWwuFZROZ0NxEimXzeVh 7Xq/4HDxcfF4OlUvZdPRpMXwuLy7NtvNl+ZDczd38nOBgk4Pb0Z1fRsaFxcUhmMbfWcbilyDl5hF bFtDZB2JjwVsFApDUJF3f5aZrK2ikn1oSZ9nUrCArrmsZbB/TLywGk6husVNWVKKxIeokstEe2bG 03GcR4h3Wo5Yq5B31OBgFB5aDwqFGrR2skXjVJZkzX7h9HSwqc/j93a49f5P8tb1Q/IgoB0Npf4p ZBKPkrVhGtgoW0ixosWLGDNq3Mixo8ePIEOGwcLoIRxzR0o9WInSSikFMGO2Y9TNCEyWNYskbBKz JxL/PuQoffJVpgMSBWaItTlCy9YZXOOMGnlwz1JRNmdyFuAlhdaGnZGERdqQpIwCgx6ElRHy4JOw K2e2xkViJidVD0w9AFLA623UlEkLOQI0DtfaI0U7oUoYtoC+nUXijl05mMtapHqPkHFMLkldI6hC fTL0mLNUI2YgD5nLxF2RT4D4AIKt2UOVSAOFrB27xDVdDzWp8n5tOzJw07/tdm7ylwgfsgVk62ZN JJIQPm+LlLn7TIjvI5+rkw0/ZLRxLt/PT5XGnHr0tNczF8CcE/777ETK8Gq9HPxxIsU1Vl1xQ/iW HoAeqCaEGRto1Y574UknhIAF/iehduS4d80Z23SI/0Vq+UmljyYE8nVGQgeuZptgFFhlR4NKfBeF fO9BxV55pz3HYhplRHJaEvp0JaRTkLFTgHlD+GiLLxVCh5ok2c3IoIP6sJFMNxceSeB8WwKVynQ+ 8ufkkzuNo8GZ6VCHG1CH9KeeEApeoI5WUemTW5Y9DsGHc/bBCaaGbY755pFTUEIJeZHc5l6KCybI n5tNcrZlfP1gllCfNSKmF4gxQoogPI7y6WSiQnwyJqMFkNcpXm1KBRRkWb4izDhYYjrEdnj05qmK lrCxHqtapnGXjYLy6sSNcJ0Wpp40eieNrwPidyteywK5a6NcIKWUfEjK9R+qqpqC2o8V/sggs7nh Mf/pfZpyuetmqKZ63J6aStXtK4429+Q1guq34Y92UmqEl6A1Oy1bQ70RDVmJAXbctfJWQRuCRtnJ SETQmYGmoSbCKFex05ELlKLSFnBXyT5ecKZD74Xox1CEUXIUJYV04GB0iohCRTtSODJkV/P9LAUX XkqRW4EyayJzFkdHlFM6P6sFciE3h8SSSFhnrfXWXHfttRvXGKLImf2ojKZhY3t8K3ppR8QjmmBf t/JbZxENMka79qctZ2+xAU/SvirAB2TwQVEQcC0e6XFbb2XWFllUSXz3RUvxDGyqaVh3GIBiObnl jM4pS+7eBI7DJRdTfFS5c0jh8t9Snu6ZNK1J7j3U4WkGE4r57afrrPpAe8i1mhaV575WOozs7F0e 6SQpVeQD45WWyl/1Dm1HTCY5NoErRpGH8dQeqnRE/0E7Tih7psUaUlwkjX0/BbEE7X9rxR6+7mw1 uFLqokjVuhFSwBxV9nIc93Eke9HBBVVKQT+80ItzvkNK395guv45TyfFycx2ese/jpDjHPuLzHiq YKZSeews0DGfbRRALvhcj4UIQVjGABEJmByngxyJyMqwoB2yUCIiZUubYbLjtoGobCvS0iEQk/QG LYjCbl7rAkwyoaAmBAEAIfkEBVQAIAAsOgEFAJoAMwAABv/AgnBILBqPyKRyyWwuFZROZ0NxEimX zeVh7Xq/4HD4cfF4OlUvZdPRpMXwuHxuXJvv5kvzocGbO3p0goN0D291G34eGxoXFxSHRQ+JflOM XISZml5sW0NkHX5URmwUCkNQlHeAmJuur02qin+RRKFnUrOBsLy9SGWzgEzAsxpOFBobWq2+zXBZ Uoy1R3az05J9ihvMzt1xntSyZlqQWNyf4meNj97tcRSLWwqGGrertfBUmGTigKfuAOXAm3UvyUCC eQIqnKMg3ZldSSYR1PBvoUU4/JSBO5ZsipuLIEOKHEmypMmTKFOqXMmypctMWBxtxFiRyKkHOB/U ZHJKgc//n0VinrM5L6eSnUd/AkWVc+iRbMrYPCxQpgMSBWamtTlyK9dUIfCsGnlAEFNVqR2GApNy a0PFRMYSbUhSpmExqn+8UowYytiVM3jFHjFzjqwHrh4CKQDmN+wRrB4oGIIUCN6uMr8AC5Ho4R/c AgORCgEsFydlLlWHRNFsBDLET3ryJSFMKquRUIdCg2ZdxIxo3kpk20ospE+gUK83Ry6QKDneucOd y10ifLAHbmSnF8Hd+/puwd0LLzoGvA9040JS1y7uwW+RMtCH9HH/yXbw8UhoE1FWQP8Q7kTQVl14 Y5lBHngFzMeeYv4N0R579A0BXxHNGQEMEwMSGGAVn+23/5xq+GXoYGfWbYMhcPqhJ0SHIGKi4nv4 jXhOIghSc0Y5OGLhGxEXiDUQhR8udsY/Io4W2WSSpXeHiQbFuNouL/5oi2DmIZnGhGABCGSNdeTF 1pc7/veGlszhEoowIMbXnR/urTaOUwOxEQ0zLxagJVZvZIOHWMCgxWRtXAYVoxFh7qbBofXw1lw2 XaoZoHdCINXjHUOFNVBydWKZ4GHyPYiKklQklASNJzr6aCvRREVJK4lwCFyR/ZFI3Tg2zjVQJHVC 9o+nCx4xITBO4SVrk6bKqNxO5g3RqhChqAlrg01yKqhY2dRUZ5nGwEMnrzzixygShjn3V7FGYsJG gdICGP9umvlByoSBXQpGaqev/XiuhxGC+t+gW85Kbqxc4InYcR8Ki8mz7tpEKJeOjRjftbGWgSu3 EsYIWb6R0jpWbPyeumlmYpFJySkNEyrtFY6W4VzJuxG3KaZ31Oacpi1f88CZb/Axnnqt0dbxiFUg 151VlzqSDHRmIBqVkEzS3C2C2biar2H50njBoRptiiAlSkyKy1drkNvQNlEEm0xco1whBSRfflmA Am2zxYWeUogLGn8U8peFc8mcU0/cxmRR9Z8RJfkSEUYdrvjijDfu+OOQC/JRHYcwcihEVyN6meWE U8XFGlgncyWikycYeqQmHq3MKae79LPFy8HjFxv74H3/rgJ91PQgFBIZwsUU+2zVnx43z0VW0GRz qMdiLwmv9skfJoIXoWg7+MZqRNSjLIICfwjP295NgcrJzedLkcv9YbJVx30wB522ygq8omDo/2dV 9FZhxQXeo/2bEpqfCJy04iG8+ikpQYDIwvX0oL35KacW7WvP1dwCvv21QQstw9j/XqOMQ33oSFHQ gwGnFxXydTAR5vJRwTrVnz4IRn/uSxzugKMSABZgEjm5F6Qww77D8EcK6MiJ+JgjFqwkB4hHchkM +dcb0ZzEho2ozyl2eJj29aZ6WJnd9Th1LyIWoXt6KEPAwkeuDjjRJIsoys16M5fYeQp4qIPOveBh CgQ9P6iLcNvLDYfoskT4hIymWQPJAnWSs4nuNVlwXzIwx7nLuOeQ7wlchAyJwRW9AYOpU9UkGNG5 yPHkjHAApRyCAAAh+QQFBgAgACwJAAAAxQE8AAAG/0CQcChMDAaMZJLIbDqblcplSr1orlfi9fIU HhXdsHhMLpvP6LR6zW673/C4fF4WCA6NyYSI6fv/gH9lGxschoeHG0KBIBsYAnSRkpOUlZaXmJma Y3Z4ekOBoX4gGIOEiB0dHKCMIBClFpuys7S1tre4mQF3B5+loq1mikMdQqukrRATeAcgEZC50dLT 1NXWcQYgd3l7wIBnp4fFT6WuensHBwt2d5ACCdfx8vP09ZbZ277efcKFh8bDmEBQpofZAXYID9pb yLChw34aHqSRqIGCnAAL0ukpx4Rfv4DFxjUhWLBBOnUIU9p5yLKlS3sB0WjYcEEinE7cgJXJEM5Q Mf8OAcuRXNbA5EmVSKG9XMq0aS2RZKAKsdiGwC5PE0KZQsRB1SKPQ9MVNbouKVKnaN100JC2rZBi XMiwZbIhixsC2jRmHbVVXLFhQs8tw2P0aFmzKkFkc8u48dK5TWKGkRwGzJx8ezlO9ucTBFAmFgRH GFsYpcqM6dYJSey4dWTKXaS61pRKNuwht4lRyrdoTM+u4zhaICm26Ml0SQ0fHZJS8ezn0OPJftMh riScE2Jt5moo5kDBhI0fP8zu5LoFEyAMmaBU28rojTVMhz+NEM0yDyATme+Ef5cB2G33j0gYWDAc eOEddxB5nSAHSQMRnNMFO/RVaGFLaxFBgWVO6Af/Qge5MQEgb0709FNAB55TXGmpqXQUTiZxI6EQ zTDXXhlSedgBVURYJ0RdGvjYhJBMUACVkH99OI5tkIkklX+4TRZlE0bCcUFt1qWi5FsX0gYCjyBc INltGXII5hojeqJZI7pJNVQEKyq4AIOoHbSNUSDoEWN66ZGyBxM3igHllF1QcCYhZ0DW5Ic8avlh G0Q2saOhVU7lRKMg6IfoW7JlOIR8XxrKhXU+ssWFqV3W4+h+aqSZRzkmeoaiYESNpaBpCTm4AGkH RDhBAwtE4IwADRBUCgSBmnFllCCFeOkTZ0r6RDFgOnroOKCGMSgbUikSrRgeCqphqg9tOyFvPT1K /8SbpLFoZ64OEoaHr0b9ucojvSxTTnuLqREulwBrMaV8nm4w37fEPLmts+JCO8aqmfom2b9deEvu JmxRTAbDdeRTjpaOFBjaOXC2K6eLLd7ZzDkxguKZjREeoB4INU6yLG4Wu6HxhzpOF2kbGk8HIqcC p5HtfhSH9PPFjXWSpzFNiGbyrSnVaceuMQLbAM3BIuMRERsclEcvfbCXBo+jDkHkmEyYW/S0PT9R qs5PGNxfwm8/cfSnne7MNH0BKiKyaOG5q86c5aVcuB7C3rHXIsc0wcFBvaQjBLKU5DwOmFdCBTEa nuLNd7QcS4lGXBD7/WUTqpv+d2sCZJSnBYOTXP+4grGTZzWMak4Qwa5qsHcHzW4EpIhkCMdBZtxq uO23kD6m7u/qZFTr9ussNZjnHiSXLN547zYYL2nbo1NzLKV38EyDAsxcMx0e/ut5tx2C/RbzhIqR fH/+GU/9lp/SVqRARZX9qUsIrcOeS/LlK8bxyl0oQ0lGSGM7sl0OHMLLlQD+pBDngG5jzxLDzSqG BtjwxzaR0dYZnjSGvbGJVbpRoGugISzGRWA03ztOOxI3vrEIKxZa+5MyMBA5FTbALDK7Q9mSJcNb bIp118OETf43iQIUgEMFSEMWrVgoMXBRCBxyQhbLwMUvPiGMRGDfHSBggQfeKiOH0eGditJAYAn/ SwjZQcO7HKSSwTCnidPgjwtv0blMPfEtuUnFFDdWG5C1DTYKaOSlQLQpNIruflqoTqZC1wWCrQp1 ngOBGWMXO26kAwKWu9WCEMcLCdoKD09TkwqfkMF19MokybEcCLQDyHkMkpBMeMDmXpiG6cSkAFVa 2hMeQCloHWxaViwAqoYwRmkFcAhgCsgDJAMgPITGlAWhWSsXdDU52oobW2uGdmbGBOB8rhRXY1AD +HEWbbhvNfDoJTV+KYsCUMsJCjBgwITRhWqSSZR3a0PpOqkGCmRxXmzCgIpOIk4GGeQgAaBZr/Tk uHLwkgjciZKd5kRSPjYjfBrkoD5XSh2ActJ+/9bMHwzhIJlTkRCKPUqDAQxgEjzSTqIFWYkFXEQU hZRyD0EUwkd1g4ghrCKD8YxjMxLCIO0doA8dZKlWV1i/m7YNR7McBBOWVs0xROpbczEAXrgngAiV QkV20ENK8sWMqyljTndcqlP9Aoo9AouVGrQDLhHink4MT5xbfV0U74bGI82hGGWNoSXr9lWGnlEI S/tWMcDAAGHhS01AfZcFwgceXAYLlcA74F7FQYSR7iqogDULKZCFlJMs0QuJTVXpblOpZarWqw0D Vxpy5gSJdCsgp3rAIldHMbzUkBkZ+VNB1pGH8tCqrm2FwBG3RoyQqmtBh0PNIqBRWwqtJpdKgf/G AHJ7oYX+yD67rRshhkaE5X5VksrU1qYSSITIckGS2PzQfOsyhLU6Qzyxy0qe3rUMwQ5lMHZyxRFr xhWoCa9OdaIZW5F4mqT0VD2YY297WyolylDgv02w70yFENkvDaN/bhhhmGZMpSIRYad78B4uZQZU 6/JiIGEZbLEi7JmuEOGIvJjT4U46Jxqxo6o7LGVzUroaaor4OfwN7nvhqzr3um2xXqys2rrIFoRl B07yEiweGawRIF/XQU+zw8cUMdKikDR329hjg0mJGDljgLZz1cbjrlyhFn9QLmHgr9uMe1MUl8E6 ljxrTPGojJMYJ67mWNDW8mAOWkF4JXKFhET/y4nOO/PZpENYX5+JdV6UHbZGTCR0WwSqZWICt5gr 5A/bovIjJkzTxjBdlw3ltSA8Qnh7nfb0i9AzAam+1hl/shEra/YnJK86KYWlHI1kvdWFBbt5BS0R cIuhuiXJDazWYUBBbphmpUA4K9H29ETZMd1buaywiKMud4ll7WurBJW7MGyN3sdtxpC7DdvKJjRl 2lAq0kUNqGNdGxxQkMHY6j166ukQviNvsbAjAqgtDrURQqeiFBZC/rbuggUQ8B1idQj9KjhajieG 20SWv2d6UhXCZQW/ZZlIRLLMz2jS8zFPjAkRYrfI1yGsSqdDMw9G0GBBvmSTu2dsw3NRQtLY/+de OLm8i+hgzGXuFIM1MkdPqOY2w5A2iiFqm7ApwCF7FJIyUAwytAZbTR0OUD4xLkHQCG2NeBl1gryI WNqNHR7KM5rVAJZO0FBE1/O0auK9wmxkd4yKM08GdUv90twTDBGGE/WJClk9irfT4V5I8nj2FBK+ M2zKPVyjUQsBL5zPPbn8XqtLc1f0RNBD6VU0WJkpRCwERwwsEWKU2dsB0AEXJ1tvr/vqX2hkFr80 NM7BznIIX97EJzJ7JmgSVubhiFXl464ggdLkzAzQCcF0iK1Pf/hgX8e4DH16aBf874O/qFeTHopX FJ3wCZZTNUgxT6PWZ4DSHAzmCrFWf+yVX/+fMgU1ZoEaEiR2MS4IhAUbiFmRYgXWMRc9xxZWNAUf mAChx24Xdzn7FzXc93/LIE4J1myooT1/4g5IkRHmBVXPV1hrVFvt1wzzJ4Gy9lIDpXZQ4V7aolw/ oiljsEibty7lUxLGUSzbYyBfQysc13E0uEE2eFIdtAexNVftxw4QABnKlyfo4SIQiFtGeGWRYjcx tEmxQYF0yHD9VYfUNA51EU3+1AUUBwG+gmbiEXrqwRGFN3yfFlc2iDXaIAT9hl7NkTGfIoQHEBqr 8Stbh3nrFYe5dR8JNVD/xXMHx4dsARUzUXOKIBKreED6gYTrAVR/J4aIKBDy1oXKNliOcx7/Jtd6 OLGGvjYE4VMUjCM8oxEhgVYznwiKWgUbEYdJzsIjG7A/AfGKQqBidUdjAxUxfEgEBGAgn0c2ypCI Q4B9nsaIJ0UhDcaDTyZYe+GDahYGhOUeedEuamQHQ/UezeiM+kQZvxYwIUIVlsg6VqAFwyAR2vgh VxIT/lFITKAA+lcQzLAHyvBTvSGD6viFX3cYIMBdeTKJrLYukGFtHpcQvjMa1LV45dFvcOiPveQs LyYppuiNtgYZBGZI0cR3iLJZYpY0TkAA6ECRhCFd7DQMMsh7ysZHQ4YTbiVRIvkeTrBHLMkOSOY7 lLOODAgC/QiTK/UzsiFjAKMfcXF3MbEB/4BoRjtCRX7odk9weVJnlE6QlOrIlDR4VXEmjMSYOJNI GHBilWcoW17ZS2uhAJYhGZwkTDgzWbbWa2PVBGNkUFkGAsqlAWOUG9zjK2LRDX2ybeuRlP93eJsm WIEJa52AVXw5V0fUjhukarM3mL3kgZcyFxp4JkFykDmFWZMpglbAIx7COViAQMIZBrEwUV43O5/5 CsYGmh2Hauh3huxEeyJpQwUIAlDmb7BJf2Y0B4YmCdJVOZ/wNOd4Dn3AiP7XnHv0kXhWThGDeikR I6oJV8Nzna8JAriXnfhZDfGoF2XTfzNinkr5ZiapnttwOe7ZHJzIfHkwGs5Xn/eZnxCKC0UEcEdr 0g3GRhIuqJGhyUeSiBNlCGqTKH181qApF6EmGg2dRQoZwBMa5hHyFgsAKoOHt0FIxkflgUq15Zok Wp8n2qOSEAQAIfkEBQYAIAAsCQAAAMUBPAAABv9AkHBILBqPyONlyWwuNdAo9FKUWEFUECHJ7Xq/ 4LB4TC6bz+i0es1uu8WHOGQ+rtjvFfBmv0Hi7yB5AwlvhYaHiImKi4yNjl1xB3MQYH94XRl8Gxyc nBsZGXaBeHN5EAICj6qrrK2ur7CLApGTX5ZhfJwdHSB9lnaTEHLCqLHGx8jJystss8Ndt1+ZuZ2+ lsFzkQcg2yCpzODh4uPkjM6SlH5/gXqbnUPX2Nra3EICA+X5+vv8/AbndIxEw6RJFwdro7Blm8eQ 2wFUW/pJnEhxmQIQu5LRSlfkUjt3HODdUbiQYUOHxSqqLPRgpcsiDzTsmskrzAWau/qoAchxlCj/ L9P2dDroswJJYSaTEnl476XTp1DLyMSpgUhLLjhrYtm5UWSedkOF5AFGMqnZJN+iquVyde04nUZw Iql6ZOpMuGwI8PTIJShIr0fNCo6DqrDhtG4xJhbTdrEjuxuyak2Sc0/WDRQK6d0IyIvQauyMBh48 +DAqpo5TN06djILkDpi9uJaM18sFKCAufun6NQmfI6LLkk5aSrTpwvhYK19+jALdqquxSo5uRMHN rHQhyfH8mSjZ0cNNYrvDtDBq5k8nox+XGUlMnH0oyKdO5PpMIUvaa5fEpbvY7/KER9p47KRyWERu 1HaGgkhoBV0Zq7V1lUy4xKVYEbgN0Udj1KlH/xeDlGW3XiLZ6YYRTb7VBV8ZtBzRnXfBKSTgYJNs VNwp3hRmiIgXWhiie0bAxWMReDUGm4bqgfCgi11kN2QbSY5ozAOv3dVFlfeZ0SIR/rEDAngzmrUQ JUhN8tNhJrIRnYNRitHmGx08WUacGL4J5BD0YSglMnbRFNsXtGVBBj5b9jKUTjEGE6ZgNW4nBC/D QDBWeYyI6OAZeV75ZJIgprjnp1/I2cUDt+GXBqFyVBAWO0chtah4JVHyk1jPiJVjSnrQxUtNFDI2 RE12FhIsG6KCaqwqqPLHi04YgPmqeMOIUgGI/ElqVDGIebHrrz0SCUJbnaoy7CLhNlLusU4lm//O V84+G2mLpkybRDrr5vGQN2LwOKSCoj4nRLGGjIsVRZmi+5K69ArnrqtkllnEZEl2QIkkcZBnIBgA E6GewIvQOcS+4XDMlsHKadOqu7REWqakXz76632TcTAxOtuIcrEXBY9xLs5swHVuRsp42CCeJCeW yskoU6yyECyPBVdWGrfsUDfCWJtOtkjsnDGmcxmRoZtWZT0w0b829vURLeX8bRIcclk0VAYMIQA2 EyQth42FsvwolhxU0E0cR0gCzNtmqK2I4YaboZ84BTTuODOOFzCGAfMMUZLd6IwpKx3ADnXZECYt Ve8pWBNuuhB7/ItRbIszmbWgQfLBS+uAzmT/4h5VHXlEe7KnETHQGlrWAexTL830s65uwzDTkkZ2 4lC67BJS8ncDXoQ2wNyb3OlvK+B87C5T1qbucbUOMYMFAF++2w3iJRNeWqlPZB+9rh31w3ARsBE6 Xyo6I8PJkxW3MAK96PHCb4IJxDa6ATrA2Yx7pvve2CijovHBBHh2etPOwvewIdwESbTjYJtcwyMJ coMjwSEC9ZJymnc5qhTf60BIisAB4A1Hakeo2gNLB0EpySRjdopMmlCHkU0FKX5YGeKjtsbB+2EB YkgQ1Ad35zEPDk8I/OlfIBpVvXmUpIWxYh4IZijDAoZlheFJguC+goq49RBUu8hZFY84xFLt/0KJ UeqAbjKoxNWFIY9ZuIl+5PeoQL5pjhysFjq+sz+T1QiLNOOPUXrROTN2wihJO47SgFEMBL1xRAJD JJei1JL6fSxiGhPVIZnIKa0IUmPE69YqLWQAAqTDZFuMlRf95yjrkbGMltTJLumRQJYxEHSjw9Un 12PKCQ7NW038l1YkxwvHUUlO31vNbMY1mZZM5pW/KtfwHkDODo5yCAwgkxeZZzJH8jKSBwgJMC35 JcHYgZhiqocRlCYp0i1zRM0UnyYGuovIFaA2HoLNb+KCzZxkCUm70EAf96aBhdanA4szYbdOJLyn baCiOjFROjHpRVMwzEYyioRDHmXJ6Q2onv+DWalK9+lAe4Bge/9MTUAbJCqNDo8JG+3V+Bpau4FR KUrg/FWx1CO5JZ4oh++s2eVWBqaFjBF6ffhfQ5QyDx1dz1ray6lyyIeVnuoRQ1JQX68Ces2sjesB kZFT/DqwmqTuTUPEO+TLiHCRlEZicA6hQ6umihRVyRCmMzoePYr3t4p95ZiQBCsPxaoWQh5BlEgy UZKmKE0k5VWVE40LiKBYBLsqqSZUKu0sn1gbv6ZqqplD2jC2Q73LDYikDazcCXuyT2vhKzeUTYxl GeqbsyqpQaTd2+Iw+6jQ/tGcVqTdkYbEWeIqlQjpjKrgAtK/fg7WkcTp4m0ZexbCHOccB9j/YXDd 8j5tXWmAl3UiCGYj37g4t771NWF1QaiEESJyMrYMEC1S+CWjJEphkeztPW+olKVY73r2OE1h83Cz 9UZFo0NQQHuCVZP9auxpdQIxcrsGXR/haRft8fDeGORfHqkPwdt1mNUGG0BIQitMydvn9TIX4VlM mAEVtjBUNksn10gnmg+rCYYjo5OaUIAJuvrpE4Rg5CFUmYoKAtpOn+o1V0Jhw5etSQJg7F0zGZjG trXxjQWUDX3SVHCQ3TEnJyvkivBOE0TQQCw/Blwv0KVU3MFz8ARNST6E8GOxFJGcqKDECww0df9K tAphnEszzZjGlRMT/9KIRTXSbD9bLIYb/+tMajdc5L7hIHN3iwOg7+KzwWgkzsziPLXdvFaZpc71 nmCcXmz4BM1cnK14EEualXZaxzouTwu3i2tdO3s5vG4Yq1vt6kZqWqWc5gKtRXdCNmrh2eBWjmzL XIqEANu2tt1fjstrCjc7eBtVUXYLkeltT4Zb141pQuv0XR+gAqkJpfU3fprwOK+VtgiyjW25qY1m 8BKnZdjO58SQKQxjv/mYgrPpvS285+PCdyse57OG8LOxLJCzotWpDwdDqmSiiYoBqw62Qn597nem u0UCqrU+o7BAyKas4vTW+MbFyiDqgGu+b/oap1T+sSwT8eNkGHeMSFFzm8eaq2c5oRR4vv/jhqVM hdei89D/SQW8+OzpSaBLS0wUS9hh1FNEaKqpwEDuYDAtOD858LmHmbQ8V2UOUdhxbE/4aSyyrNlj X6/PAvmoEPJCUDzKDOzcrgTUXSAzdJF7Rd1+RagKJ2HS0nvNvfjSehavHrgBPG4YyKjQEd6riafs bZZAV7T/yvFb2W92XIlfkPcBL5qniwIKzqC6jwnvY4l51dEtJlNEHHBV0UA6Vr9jhFtVaUs5TOzF qgAnjZxbG+i46jbY++9jtOBlcIDxqxYMO+xB9FXXrSOzFzoIRF8KRkBKbuE5Uy6IffugoiDLhXZX VnlK0ji8V37x1QtQVwZNVRalUBw0t3ztAiZe9HcSTOMvCPdgx3NLi/UF/weAUoIXStRkTBdyKFh+ vGJ2xJMFb3da4fNRYzBmyrdG62JmFOhaSiNepGc5IlI9+xdAQCcGqWBvIggqVLAEVDYX4jd3USQf RsB4B9ckqqMns+cF0tZ+WlRpDLd8pJdAdBFnQBhZXKR/ZlCER5iGqcY8dreFUwd/o9dOrpdb9TCG UxNsHHiGariHy0CDidJu7NJ+cLh3cih/NhZYD2ZtkNQGIciHjtgI66IhEnhgXRh/hVhe2Ac4ZdJ/ hoCGj/iJrSBAluNbojeIDfeFoZNFtOYqsuCJoPiKaxAEACH5BAUGACAALAkAAADGATwAAAb/QJBw OCQYCSCHQ8JsOp+gJlF4qVqvWCzo+pRUJcipeEwum8/otHrNbrvf8Lh8Tq/b7+3EYCBk+CuAgYKD hIWCVhqJiRuMjRsaFxVjGiB8eJeYmZqbnJ2en6Bze31/hqangVWKi46MGqcMW5KhtLW2t7i5uruW pai/g4iKrY8XZBV+fiDKu83Oz9DR0p+9DMDXV8PExmLIybGjlpYK0+Xm5+jpuNXXqNmsjq9i38mV e+L26vr7/P1uBSAScXNDYSAmX+2CqdLmKNIgevXujRIi0ZK/ixgzqqPg6oGbBxc0ULhjoBKphApX aWj16iFEZRWnVOSTQKPNTORu6ixDbMNI/zTkiNkpyQ5lhYUMHxF6yWymRYoxd0qls8HgVHQ5yXgU CoICBY9mLhCDZFVOUWxIV8ZzCXGZvZlQ38K9euYn3SEd7uozZlcIBbWNKIkJCaKAYcNCiPW9c/ZU WsCuljKFGvVeviExn+rFuzmg4DQbOt8S2zMw2EmlHXXig5DQ421s6bmlHM6yUyISRU9ZfDXvGt+6 a5X+fKb0mwu8ySAZZc1UyFUsBTFtelsunwG+GDy1HFy3WDbAu9N63oY0V9DnzSzvY+g5PFcOAU2P Zf127m+CtpusKd5OVmfJlRFef+ZsI8RpZATFUldfnUEAc82l4h5kSgUyH21OXWcZfRBZKP/AhwJM tIYCoRFhVYlnkDXHBh20aOJILFLCCAgkigHJECy2iGJiW7T4HxEatOjif0G2KJKJxuSIl5BjLFYQ jjsy0sGMIOTYQVkEavLAjiA88NeCZFyAYGKtUADQGg/ugZBn720g3XQyZUgbM9+wtgyHIIKoWXF2 KdBBVhTkRRgRfQ4oRCJTYCnElUMMVFWUJXIJgqFkXKkojkTsyCgV4bE4UAeIkilGVSZyOSBwF/iW apahpEalGa4yEiAaG0riXnQWToZZhhNtOERE1sTyTR97soFikJ89sugQgZrImRB+/onXj5mSweIU r0p7aInfJYqXpIRS2qi3OIYXZLhiDJj/al+rPluluKxyUoB58aShAIVUnvnGPX+02ZJ8k9FXH6/Y CVsndkcxIknBEQ6QZxvaXumbnzj+VFV43AxKGjcrCcgTl69ugZddxC1rMk9mUNqBxTu26+6hJbs8 srvnxmuLAk8iB0eodEBY5Vq5voTZwHCpSUo9CCnJWjLyxcEXsyJX6+e9gmk7KbN2rRwmvKRmimKz 6QopNnDwLqpot9gKFrLMVw8xdaKSdt12YlPabPdbf0QWdFu7Fl2bSRwWXEmEgEwqtgZqCkvsh5n8 +Znj2Hrl28pgj8F2pidqytumlZ7B+RQdjwqliaeWOljcn+5m+N2s8mvNv97ASTR3Egmc/wy/gxg+ 9pTaMby4AOC5LLGNwF08atcblxEotYllbvqAJU9R9qFkVE5E8S2X/nKjhmp9svTRsy5aY7rOnls4 s/3hR8GHWLm7jtrdiRvjaqT6GbLpoht2TtEyj1f4VXLe9T53ORRNL1XMo1j+RMU96UHNct3LirhC Jr7xAU595SOYOFx3kvURrgJFet/YNhC/O2GHIvRLg/akZ5DPYWp0QLJaoAyiNgEOIUg/WuHcPkao nwTqfp3KngN5ZDlTtbBaZqtgcPgzH2aYr1c+Y1r8IkQfsbXCihroXVy0gyfgvQFcFyAS8/rilVHl 8HBUWEwVpnCvMbivL5KKXggNZaXBGP+EI9jaXqNCg0Yk0s1FSuwMOR70oWDxDUP2uQ7SggU4gL1L R+cJTe8OQMmKcPF3JQkkG/wHLRrJgWdwK0cZ76CvTZTygUChRQE4uaveqQkZYtCghiAkRXBQ0Ro5 Sk2VXtErRGLnhMtwmADCoElnbMB/aGvGT8gSusQAsAAURAO+SqYsN/YEdCEBF5Qe0QiDiGUkYrkU R+Z1za6Ukwg1cR09funL3LzFhMvwBmssFBAh6bIq9JlIPuGyvkAIs5jqSOYutIkjAP7MWmRoJgOJ aM0hjImgosvjHkeyJYhSoSoPyOhpOEIchRLBkB1ypZxMIr87rS+e8kkYJF01G3cirAL/GfIgCkME 0HMINBcW3eXHqEUa1DwURdU8HkLXENRt2cUnL3TjRQMktxcaRlggNMbtRoGM2wjsKXVCaSBCGCt5 DAwqwYrpJSuRwppOY1ahuKkYtmTQKoUJXB4lIlutBa4aETV6ckOqOQEIVKaWhUvWuMAtXWkNp0QE BAfw3TwFYaVYVXV2fZvlTMYqMLMClEQ53VJxeAi6uJVorg1V6l0jytCfUStKfoXbSAxgAPUJzqQQ us/BAEfVrdozVi0NpoiuIxdwSOQAeAOmdspqWfFxJLNNJe0L1Ro3wWiWrtBVQ1FL2zJwodZaNkQp b5sz1QFUVZHr7ANFQKDSlQ5nYRu6/6qISHoZomkxmMQtrt3E0tYDTddrhzEMHOO20aJCFEU/Te5a i+pRkNmIOFw6TXJRZAACMNK33D3p+qoR3tnQLVb4lGwv4hQny8DUqnuQzz/lK777Djgw0GmEGeL6 CEQdyY/WdMRiulmGioYqjBKFsVu91ooXUuJGQ2iwwWDy0gm3dDobpg++HPHYot3JGOsdmgaDe8Lh epHEdjPxFLZ0qR3bF0jTjZR1YSXNRjBvrrISLbN2hEcdY66iYqgJSMExOBPyK3GyUxx5ewJLOdH5 hOjTTGb2kNjEug6YI8Yyq9Q64C7vSCBXoOAGwHLf/54SZWOYK5yVu1A3pvag84gdkf85pEUPXuhX AgvMLEgKRTvlg87vxI07GWDo+yD6Q8VStGiOi4bnYrq0ODJIlLZM0Gj+mtjJ2sApJfVNYFfp014W wlOFZqepkheDSB7cFJtsUi3OktUh7jN3IkveDxv21jTVtXgwC5rN3lAM7N6W14jga6FKV5tBXQk1 B/zuyGH3huCidiUcGWJlNDF+BdsgnitrkupwtzKyrM0v8wki/qg7ODnVKV0VYBhtrmSZIAOwlo1t Lb5SU9jJCY11/ZpfCjpgMoulE0oPvmEnM1zDwdT2bgcd01m+lwHxvbheoCngtHE22jn2aDJHDq4x Obug2LrubozdbDdmt7VMuQ7ApHj/tPlsGG/vlbVkdbu0J1ry2gMALnPWe2WhC1LfD+WGlkFd9IWO mUxe8coaD1oQVQDEv5eyLrf0GvWS930gHIXbjuBUbfy8qYlfj+2r8yFx24S4nbUjVs97kWi3dwZf aAUd9eri0C0nIqOrODC8k3qcG6EVgKDsSoqycqFw0yM22XZLqWt3u7hUB4Tm5hXZedU7YXXe88gn sYOzPecPHvykv/oqCHFjHYT3zexyUpPRrJzJ5Hvfsl4fgqhxH/5fbYg5C4u1hkT6y4hP1vLFh68A uv/9+rMuv80/2Jyn8PzeA84eE8ZB6NNwcqFzERcFEuBKVGZ8QWd/DhgvL4dkVcY0/4/Xf+IQgE0x LLEWS0UmfHsgAeSFSCLFgG33gCaYBqFXBpyUBaikPI1CDofnTWOQfzABUpLRf06UcEXDAFAWF2L3 SvWBIe41WfJHTCeYfPgmbEk1KDQSKgiWX9CkggFBQxXTb8fyIn4xBqI2LPPUGltogah2PrijIbFk Ph1mWB5EhFZmhEf4gAqFIo4SUUoIJDYyLqMyJs9VIkD2dEF2akNGfjhYDefHHNQnaNXBgZakHbGj g9t3fG14cS/WJNVDBUo1hzqWLJMQM2ozesFmBkMGERP4QV8YiKTAQZQHXoZ4DyAYgkQQfAwzVQfD L2TVgI9IYpEINbzxF6yHRCJREP+ncRodtYusVxCHwSU6A2pj8HKjyEWxQwV7g4P+92cNl14ixluD MwurOAQJyHvEQgo5p3AwNYu1KHS3SAVVAFcwMlQykijIIRZZgYmiNRII9oL/0WYz2G3DYjBb9YzQ CH37ZBv0IU/rBULR812JU4ARoVh3dg+0OI41VY44RjViYI+VCDMmQg73kjHwCDrOFW16qCja1Fr4 aHCO5Blb149Z1VJ4Jl69NDgqkQgGKThiGIDDZ3kMOUwOqWhopWyiQ5FEFIdDxYSxh3Q7FoVTmFBl QIOlwAwDgZIv8XXspYA/yACrEJNERogjaB1EM4tsmJM1FUYKEJbRkySU1m+NIhjqPKOHOZYiSxga RjkYB9JWSnkSJemUoBhLRiZry2BosQAB73SVrNF+ieN+FdGQXllBVxAmW2AFu3EFdpGCsheZitko Todji7l3jGkGDnCSFEg49TCSTolVG2iNvMRPgPmKF4R9TgEih9maGBFhjud8dGKXKcmSAOmXsxAT CZleCCeYhLma8+eawrkPsLmUgBAJsgGaKIkPENZhrwaYXHiKv0kwH0J/w3md0qCMh5BF9CFVyUmb Kelq3whFCVlnumUPtTad1GmY2NmeuBAhMMmUoMmZdnmB+TReABiAtqZh6jlSwsSa7hmgnhAEACH5 BAUGACAALAkAAADGATwAAAb/QJBwKFQMDQ6icimUOJ+Si5RJVUqvF5BjmzxWv+CweEwum8/otHrN brvf8PiZwZALsXipZs/fZ4lPIH8gRnaGh4iJiouMjY6NCQOSdXF5eX18g0NQDhIgDJIJj6Okpaan qKmLkgOUbpZ4fEIamk1PdLh0rKq8vb6/wMFwkgSuarBYmHtKULm6rAMEu8LU1dbX2IzExmjIepia Tw7Oz9DExNnp6uvsYQ9TbIVu22neF30gy4ASXUoE0uYCDjDQrqDBgwhH0Stj71umTU6q/BNIcUDC ixgzJqqVjwwFDUpAzovGDYw9cH88eaLCYGJFigQ0ykQjcia2B19q0aIgRh4T/wo+0RiYVJKKN2Up IxIphusfwJcVbVLBKbXqOpBBl1ygaoWrkHchQRSIM5RkzpN9BjkpKqTlU6hQrRLZsMEqPDE15ZKS xXCWPiJ55SxkchQTRGdMczmt+E/I4qh6QXiN/GUyZUaB3WjgKeYdRzCDrVhCausLnccCXQrppBTm ZauZq1h+7egCZ0UFPmrNuiQ0kUv4bJFLfNoplcZDnK2UAJm2zLpkZjv3pfPrkLFkbJuxKDpW2ibD hyNfYrwtOVxD3rIiSCY24Hxeb9+RIv9BfPdLNsjvmEWfhsmfdfQeCNAZVWBgF9S1QYAiBVagEg8O 8dEetzXo4HSN0CIEdoRZ9v+ASAWEaER1acQ0n3ffKcWSW9wx0coSoCjhzBABHaJJhEM8eBeB7tgn IEggUeVfZlRt8J99GhSIE0/SCejjfzlK5mNIddmHkxRWCjgghFJSoN9XTHJFAVX7YbhXk1z9NQR+ YJhYzIkO+bFJFaex5RgorOTSCno0UmFOGfJloUmAD0KH4xhGUpGZmr99oeQY0h16oBVwPLrmoWZW 89lmapj42z3ggLDWeYiV54+nyX0hUouiivqWGgoSYRlIGxTZqF9D3ENTYH9huqCVSEKHU5OzVCHp mmwO+2l+zFqXa6anBBgGBVeMycZTyD4kqp3FtSTRU8QpZgWtQrBKIyuijFH/U6xCFLjfjs1i2t4S akLnJaRsxKZhPslKFsaiQ0wmUpnQRuYmYNIS0ZRLcO3JJwjmzqKjp9ygS4aCPN375bi/xWZou2ks mpehBDNBbBi60mthZf6uyQTAzoYlb8FSHXxHqqZFM56M3DzsGCD5fOwyCDGhCnEoiOKVIBg85cXm vyozUai0JxMoraScMaqEsiBL3WzLUidMs0xP8cnWwjufmqcueLVLF10uOqYSNH3d/FmEM1/MYNRc 9o1szGrsdy+usoGdd8CyVqH12FVFEzETxaVNY0nnySiIoW9nPrQkPzs2TWeIW4b3y04jiHKxIZme X015zQb31lUMolO/Yho7/1fiUTJOmwIvghG55OW6QmodMakkMYGZJ0/XINCclt7nqoZ1Ohq6+S2I GWJHmFnKz+YYKdQDPiAvuTdvKb3ucnEuwfCRH6dacjOWlKTyyueVGtFKcJ5NlnDwn8aUJmMDvMJX NSk5gjdnQOCGjKBAMoTogQWgSgOVwCE5VHAICoBgiMjjpk6cxylGSw7Fhgc0QczPSHxQHvPO4T4i 6A99vWDT00Yhp6HlQ1qLywfBQMUXWe2Lgk/7oQYumDogiWVLM6yCfGTBqfyRRwv4+4RbJMcU+LWk Z1J7mzK0WK7msa03chMVKwhARBgCI4mYAUGZ/iI2xQHKOskCFuLO97JGof8xdWIYlJbKFS5vpSeK HMSTwypGh/zQRRms66JARLUSMEjgKRM0IyrumAj8YOdKbmQZpVjWRr6543pKNJ8SjFBAesGofOn5 BwMeCbnTNM9cnlofyA6JyJvFCEYtauRxmoAtSQajlIzoJA6ZUACRcCQLAtukKcsIyk/WQj4lswNP RGEMbiDHj3/03As/wc22ROGEiPwOxL5ljhB2zlPQ86U6c5JJrVxHg8ikYzPDQkQjoBGTRMiYEKK5 BM7wMw26BAgYl5KnVMlyabQM56om4UJz9GyRS9HmQNaJPkoqSiwazMu7wOYvPdYxJ8xMXHUKQbD9 4OSB/1xmAQzAHk9c0R//IkynNp1HiSQhL5w37KZ5BNmwOtjpH41EB0WHajI5tnOP84zdRYH1gEga 5QsEQ9AgTCqbILXSnAKdHBMAgotWWKiWNQnILZnTsAGoyIlAPZc5iXoZQbUHp/TiyjEFAarP7C04 AbsjLUDVT1NOpnb8MuKa+IrRDTYhov5YG3f68TOuPqM/cD0aNIoxDZ4GZK19yqYWxshWDLk1X0fM JwVGi0pQ8nNvE/wDmxJWMk1oVI1rWJ9iHrcUAmzBTw6TBA+BtCo/PUORjFHYS5gh085exqIf7d4S 5CG7pJZWlNGTFmur8MAm7rMMPlGAAj5YBe7EhLHpKUcXO6IhL1KEaIot/6skVhIxY5BVEiE1LrSG icHCopRSQnpqHeMrz1s1TQkptW9uyoDGrHZulYeVyDZZJdOGsbenuoRpFA0sX8bhM7l0PZ0E9bvM eS3hwp+97kUHmB3nQo4VjXTKcsCrWQbT1rLDxS0ZaNvLCsulP2C4sClxp8zrnWxv/HWmKEtWE2CG Mgx4OmwxisdIMRDFH0kWY0UoYS71/mmciJWsjfViSesM0wj/NCZHUafjMXTSy1AFA3JhN+bjrFfC Z31iF312Lhg71IXlKkMxHjwNAniixlt+TYDRgBN9daTQUB3tFZTbtnwCbgnYKZOgRkstj6Ihyo0N BD8kMtNC6nRt6pmsev+cQNulIPgLTAZ0oKtimK8kDB4XUCC1GJ2rP8RJH7ceGG+TFaDm/uQz1FJG riR95lhmUyWbDsOT2/KFspp4CRHmdENXLRcGUpsNLHYiE5A9Bsfe0okXsPM00rvNMrTIaOW+troZ ly431yHaTYZimwra4m29BKtsOHf+Sr3ufmMI3l9ANsCfWLZvsyS4OCNDSfgtCfb4++EYcvhWl9CJ Oek53eMVbsMS7CdAYNycDYf4uq314X5SGsAnRzkV5OFPsFGa5Gok7RhISzCAU6KRKhr4xCl8yrao d1swinBR8O2A4oq8wu4hkoRyxVxbD3HA/dygAu7B3L4SQQE/nEWsIU3/hRQThynLCbsZiiZTkCO8 6xZXw3uPTm3rdsx8+GmiJrjyIY26VnGzGVF/ydCYlbCG43xHb7mNYRG4hNDPerYTIIXK9pEXE4mo AzCtiUBEsU0BSs89cwkn7nelxFkMZMc4ws8eCF5ei7ON93ciRcyGjapZh7GzLpmoYADnyXk1ntc5 pwueJ4iq6E84//y0ieaM3hPjvYxP/aplPoumAlPzz5aQEbM+eRsGXrYITkmJ6tySGnEzwnkK/nIQ W85c7Dv5R8Os8tmqXXjATPLl40hWLI9jZiYspPCmQ0QqPgXdo5r7mCVuaJdNd9ZzvQFR60dRgUFk 6sIZUzVHbfZciIN57YTxBUG2bdEmfIE3Z8+wSrp0ZdtGfl7kaclhZRiXgBWFURcVEg54ARAEa6FT ABzBE9wDe0VggQjjVGQQEeMXb2tQcAYnWWPkCS1yAazUOQUISGoQcigoSRnDJExDBcy3dNc1Gy3n aFPoTo5WX7A1QWzRg8H3g9wnbgzVKgOFZS6SW2mwHk3YhuoQZJ6QBbngf21yLnuSGiphZ3YYGui3 hPzmhoCYEHT4f4r0RUdTDiD4Yia4iIHYiNQgcWUwiNImWR0IXHRjiei1h4uoXpDoiJ6ICv2waIAH bZI4cRmXfqFmGpklGALRiZ/4inEQBAAh+QQFBgAgACwJAAAAxQE8AAAG/0CQcDg0GI+OpHLJZD6e 0GgU9CBaiVAnyGG4er/gsHhMLpvP6LR6zW673/C43E2oE5SSvH7P7+cvgIGCg4SEfYASdXOLjI2O j5CRkpOUbXZ3SX6afIWdhEKCfF4OBJWmp6ipqqusqgmXmZt+IBKetoAaGoGbSnYgdgmtwsPExcbH jrAOsn0gg2OCoIh9S5fWisjZ2tvc3ajKzHu3ntIXekTV19fe7O3u720UbBRVceDh452603lD6eoA 4QkcSJBdARC5LqyhoFCBPTuxNkWDBsgZvzxMAGq8BMJhwY+MDoIcCSaXSQ1oLpzUVc8SxGXN8hWy aG5Pk404OZLc2eaCPP+eO1cqNENhpS4KP+m83FNOZiGbGXNKLQW0KpoNVtkxtOJQ5ckvSa8IZXSv XyCKCnfpuTk1YMCsVlDCTTN07qmiCY3qEpMQl9CWcgwoo0WzrpezajFGbatxiDW7kIlgNTM5cqUH Xv+S0buXKAikBUKH/iIYYi2nhhQvZgwRHdVfvizb3UpZ9qkHDA2PUYDXqJnMJseUrrPMKc21bFlf w1PrFxFfHm2/ETlMbm3praJ7ERoW8JXewcsMv3PaVjnV/5SrY1JLghVsZgroDusM8xik0MA80LCh v/WfF0wGSGi6CZEUf/3pplBRG1DnRX8bXOAgQhtYNwRSmCUoBIQlWQH/YEVDqBThUAhqQB92jwDy gAKjObMSGD5ZUcVYZ4xXHDmJNUGKegAl8VIS5pDy3hkWFtCgZJ/FRYSRT1go1olDbJAUbT5d0BKI IEY5RGcuSoYfjBpEUVcVU25wZZIbxlVgjBfm4h2SBk5GQWUoRsKZSQXGdWcua8BS3kQXJcfjcjsS kAhxmVwgpGNoWEindXRW2OYQD4jWn2gPHLldns6YSQSImTooV1FxJSVpGHSW6qF1AVrhqZauepgq fZUZ9madjoCH563bGcVpGX4+k+Nqgyrjy2kaHOqjM25oiiYIRm4ZYlgmGnghIElxmimMCtZVbZpC OMksrCVpSxERc8Yq/waU6m7IK66RIIWUdt+YlpoES2xR7Ho+EqcHIAkqQooD5sB3BpsojWqhBqE5 GyqscsmVKroTT2tFlkpuCOHGlVXsJVh51oVxunAKYaRootH2qamfngovirCoNGwS+u67nh2cINif EMSRh+9rZuyHkLRONgii0YaJe5/HztCHsbRRsgsuGFLCeNhQI6dKp8rXXsEmCBO3+jJ2MQuBXs02 v+SnOBxDeEFrxS2KBslg0w2KEPWY+OqWbDL07RfOXuy0YUV5p3TJXxxeRtbt4v3dGEyPLd09xKa9 jAOwwdQP2P7pDKEGOy6q0GvBLN043i6DLe6llgZ+8OCu/v1siHVF/v+Z6ybbzjjiSs/pnbOVAfa0 5HBZk4kSsKWNTb+GYuReiXq5nTzNBB8qROliaA2Wh14bNnzgVXsNu6sTjttpSxPzuaXiWl9JuPbh guWm42FVpn7dxEeGKCaYJ6/8Fpjzl/NEdKf4FQoWWwgS0MSgIC9QYELle9enyrexC33ngSgrX7g+ d7HDXGFjTtKZk74Uog6uaygcMuEGNZS/uQiGZwDkmfL8VSiYJCpceyrYRjBnwwW2MD5hOIgG4cC1 YSigHhJcBL3mkMQhKGCJkICiYwg1Q4H1ixaKWd+eaDGV/tViUV34ITEkBDJjBAIpMnNcGH71q8Kw xAx6wRS20uiF/ez/wythmdLsxPIZvawvEFwSggKMlx6b/UyA+KpFwvLiG7T5IiegkJsYu1FEVchH XAqoiNBKooElKiCQIQoTpe6HEE7x6YhQgBretMUlh3CJVDjkVh8p8EQoeMRCrqzLcHxEPVIcUj3M 89kyhoaQvQAST4dqjP/WYxgfTrIYlUyFSniVtzX2jpREENf9FIfNT8HRawsLJa8U9oX9OE2UmdsF AHXCmnUisjj8wdMggpNMnMhwPVtwj3NAgL1nihGWfLFm+XxyOHGp5JZhKCiRtnOgbOYJlgCVkez6 6JhhxqIXEOEXPk2DLz2l5SzSOKDNBpYHg/lTjN1kKJgyWICfpFRp/wyLX4c29U0+bqklL81mOSdK qmDcQVHEcQZGMUEokf7SeRSqUF8A9csq7ggjzjyp5BSnqi+oxGsGgqlNZXqYglI1Y59aWEsiqkpi XsGcfPRpSTk6VJEWEm2n6dxSAWk2Krblcj0aws+EEEapjq0obeSbFKLQTW8VKIRJA1NHzmoSWgY0 rIBBZ7gCa6IlojWUfO1CU4V5wM6uBm2qu6Mg+iJSjqxVKvdcTojA6NeplmGu83SSbiQ7WZAS4ZNg OubFGjvEUgriRLS9qk6zecfO7GcQSTFC/5ajmIz+qJCFKuYzLFJa1Va3WMOMamux89UtSU24ZQXv TYu5HcWGYUZUjf9YQQ33WMbKY35DSEACArgefHUWUToyHmzKkZB6QrKKHKWKdrc7G1Am7rsxnZa8 8AJWrVq1u6CYqCpfajhWbVWi8rDjFYZqDai+BIA6citsJNAX/96VNR7uUUlhSGDuQljCoaQOTKkV SvooTrxh+KQpHSoW7wBUmzv9CWCtQLOA2JcjdwCxoIhKHrdeFyD9aMtpl+MzRrXYNvBNqECDSMqF 0Ta9NS3vcLP5JgNnNchjFkIvqptFf/QvxE7uUSmezNy3AXhzgryyZYbc3q6WFaxmpUIuogPm1+44 rDQG5ybRdbjLxrIIhcTZkZP8ZjgTsjGjA7BG3FqHtV5Pz5FRCbv/qqllrkrUW6tCdeIgLOhxikWy Xi0QWUdpY+vMt3LNbbKa4SxSR1JZ09alstkkCWq70DHP1TouJ10pNfVNc7ck8pBLTbRgvKHEI44+ 9avP3KvEoSvNWbVQpdVhX5KeQ8lLvoM9l7nuLrIbFp3ea7EjgxnRzkcMBZCiAxc33aZkSWbDexz3 kvKuIX6CCmRAXjAlzZ5h7trS8HZLanHiHhOvg87Gk/e8LaNvd+S7t9wwQLovtwQ+8Hrh6tZIxe/6 7n3hdeMwb3G6m1dyqJw8zupQM7BvpmJix/znYuQhymnIHOTcHOeb3nmSfd2zJg8Y6FDHVeVKUW6z Gf3ol865kBiT/2JltjzjPo+62MmwYMCYnVLVltGFFiw1gRtIJGk3UFgUIHSdP6bmV8e6sfKKcZ2U lr6P7KJ7qNLXscf8aysbLm6tZTVTB/pu6BJNJlU5lAJ0clwekZrQoQtAahwduk9eBnaFnJOBMZe1 hj/84rr2+G//OeAGOizkZfqfMtwaxNbtnzPQ8/lgDn1fSaoLBfheQ7ATPvUwZ+OnPII1KKGEWih7 71jJ3PhnXX52f2Pp5jlcd1DwvvdZT9vswkLF0Cki4yZFPqgLFB2RofHP1v6MlUiowqQs3kNpoQIJ L8+Q/SsuxKZBM3r1fZ/3aztkd+uAeFMEfLFReOpHYLImLxYGef9KIzTyQFYLVnuCRFX5l02ZZzI8 tmHl1lYg9gc10Xsjt2ldpxOu93URxxh89YBXphstdRiE1jTlhR+GwRsWg33vQiI49YFitmHo1hpb YDZWh4L59YLYsIKP4QXGk3TKEYMyuF0F0hKLdwHYFjFg0FCMBzVcI3vjsh+3JIRYNQoj2C+Vdhp5 p4R/53eQ1ExM+BjFQoVVKFVfIx+CY1a/EhaqtlXes4cIUQ+wdHlD4RA8OHsiGBVrqBAC6IaVc0At l1rP4Vw8d37qcYcEFndYcIHy4mOc6CFPcAZlZ0EXQiZrhx+haAUil4ac1RzIg25uaIB5NXFzuD+3 2E6auIsF0UNcNQcTtPCLkAhdb+GIboFPfTeFvLiMAgFVzAGMaUiAKEiLaiNnG6V0zJiN7WAoNXEa sRCM7JGGsxiFXSSFSpd+2piOxdCK+sRF0BhisqiE1GhXl3iOsaGO+EgJQQAAIfkEBQYAIAAsCQAA AMYBPAAABv9AkHBILBqKwodyyWw6n0yKdCqFMoUFpHbL7Xq/4LB4TC6bz+i0es1uu9EKkGFucNjv +LzeAUUr8w8gDnNvhYaHiImKi4yNjmlxdHV7lHdWYheZmX+VgSAEcY+io6SlpqeoppKVe1aeYJqb lZJ1RyChqbm6u7y9voYJcnSseJeYmg+ztLRYv87P0NHSpMGrxMawyJTL3HQEttPh4uPkY1O4Ygqe WWzVw519YbHJet323uX5+vvhD5kUaCi8WuNuEqUnY7TVu8dwDgF+EBOhi0hxiAIKsZCBYZfxjTVA V0AM7KIwT8OThMBVXMmy5RZ2Wy5mvFBFyUQiWWZSgZnmox3/hGTo4aEjDCWhopIIBHO5ZWRLBRqY ihPI8wHGWAC1ZC1yVZPAQ+9+hpQny2RKo8sIqD0rRyqSTG5BSAlzM+6jmRm3avWKd5EkkU3Ilh2K lqHaw0ccLrUrMq6GuluiMi6FVy8Xf3gvOO1SZcwqJ2KE3il8b+hhxAa+TV4tRjLrUVMeQNaSefbb vAVy80SyCvCSzBkXku42aM7PQae/qX0tVfMY18xNbRYiM1YSm11y5hU4nfcwwMDnmR1+UkidZKmT PzRkGUn7Le+HXNBA/wIR2SA0xCeyVcF8+rdYJB90XP2nX4Ea0DQdfQBBVd9N/tw3xHvzEfGffdE1 Eode6nT1/08YWXi4iRm9cRHLQkiRx1BbSqR3mkpfODcEdA9IppeMQkiGoRBzyccFVFyFwaFrNE24 Y34C7mViEQQeqd9WR5J0ZJTQuUZghoj4F95+QoQ3YhmJGeeAl6IVF6aKtNgR1llKyJHcbl7sSMGB XTboWo1TdkkEgDMuycWVe/K3Y5RORllEjX4W4SR/ND5GBJBMjrSoj1iSUtlGIsLVE1JjZjZeimga tIomxQnDB3KHLQYGkSDsSORAg/IHXxeOmuGkJ0UK2idJ+xnaancEEtijhW+94tqclZJSwCvdxUQF G8s4gESZZ4X6l3liLpGfZsYRgt5ptgUpkn0y5olkj65Bqv9ZhPkB60esOdInr7y7/mnGfsEyaUaw via72pkGBGeSmtYuY2oemcwLaosuhktsrFTKZafEFiqB4br95piGc5PaSysX++Gr7xoEWpWgv9Et Ewi1BBcsppnH8ZGwJvRGG0jD8iCpsbAY+XiloRmLBGhCrVrI5dDyxceuoh8HSulbxdb7aK4o/+vT aLW4/HJxCM+ckbz2pfmtWg7nuNWc7Z2chNp7Vol0nWmw/TSPTjetBaBB55tEv1dW+WjVWKY5VMsF E2aQHV5nluAFZhI1NihfQCr13EW79wWyQyBqEZfu/Xy234pOeWSbQn/uhd6V02ZuvZpKDvhkiQmn NdaHd+r/pab3PK7qrGUofV+z1BlIZ2OX0wb2K3UNy+O8R/oHtm0jxRFK0M4z+LdFBnL+ej665ZaA QwTsMTvtgNyODMDdMLzc9meUfa/21NG1yBJwmlE/TiDcr4YS+g/R/yFZ0N/3/mILl3GtZXiQj/kY dw9Q8cFN62GfBL/gCSp8iWq0cR+P/nEVy2DQQn3hjxSCxkFNRC11WmAXXlZWwn7ZA1RoQmDXFujA aznwZmuZoA73spmsfBCEW+hXz0D4ih92CUMKmAiO4qSXIcoHV0HzYZL21sQPEgWGjRsOp/CwwExk MVqDgKG3UAWjHU4waHAzUf00VaAiaClpQewXGhVlGYwU/7GC/SrAoKbjqyPRwRMP4MYXuYGtrF2t iww8SRgZ8jgNmtERwHOEEelIEhO1x4nEusUk2YiTSdLGMkv7FRWD+ERSQu0WA5SWEB5osIZgS4aW QKSKhFHId7hod4/0lx4v4DA0+gognNzgbYIXn2BiYY5GO6WeFAinKfGRNoFIwPdE8rKbERAlMONi FwmnxaPYDHy5fB1mYBEnLUxvJJhMo396FUf4tao9F4AJoWhTMVMCEQTSpN0kAsmMVoJxGIhM5DVR koSimIdT/FxfOFHmyWTG8VBZ8Y97Rke1dfopiflT4BwtSp10Ns9QykOi9CiXumBwU0z+PAoWzTQf Y7ZqR/+lGSRxBolQCC7UXxiBHwepMEKXGqlAU5CLpHqVEUn5NHg0AYgUdhMlj4auI0eci2VS+UV9 Auyg3SgKmcoDkFkO4S84VM1NM5RTclYSezzFoB3H6UZPxtMLXanfOrW0mSj5YyuhFCU9X4qESJz0 CNYk5FdnOgdPoUWm5QGHysg41gw1lKRMmxBPr9I9jGzogxzdqxfeaM5cZeImQCPhM4/YPXYUUJCI 9c4/DYAZL5InRWK0JS3bIomxlbGxcWFrOUnSvT7qinKZVWaMLLk3zdZToooa7TKN8FeUrmISqu3n y0JlVUI6lyiLTY8B/ofbiuwSFlySE4XktKPvovWhZAn/4tk+aCjkKq9LypWLFeXwV24OAmtEeOGK DstPVxosv7Y8THdX89h38jY3QpSRR6dUTGSm8S0eTC49+xjflw5kgJNAbZpEhV39Egc9WsuqDa2B swHbZY5ufSsKIytf4W7SVxcRLiWx58xp+XSJmbznV2Ob4auVirYa9jCaxFiU0QDYOIFMlYndUoCy sjjFy1WdMCF8xLHw1SpBNTBk4Ri6Ut7GKTnFcmfuOkzqjOcjPv7xYAXHEMQS1ptvDtOaz3PLJcel g0p9BZd6RAH9WaWCfZ3LRXgqFx5NNn/Lwkqz4pMVq4AMPpMFtHv6rJszrTTNjauldAVpSEVSoFT2 MBNs/2tJzfTY2S4BPDW02ty4bahEyIL8tFFOCsNRHxmw4FS1rieoAPStdmtnnvNAwehmV/J4zcIu tUJ3zeyqdVrD9EVRW4xg3RBf8bTpo4BK0RfWZnvbXwVZKSuuiJTYxlZNmWYkwQ5aSwcIpIDCRumy v33q7kCoKZtZBxJyM5uVdcEpAO/OAat6X/GRG6uwNlhXsUm4aJ9pkdjW8LzpTfGnHYnSueEzlFis gCbnr+MelxV8My5FiRUAo8RzyrP/WQyrGoHHvrYlQQloaG3DluGmrviSv+LGdE4kr6nbuMiHbs9M xjPkWy4CqNlsEKH8d7DHDjF9J2tzEZfGRTo3Mc9T2P+Us0YUaOJasaEtV7kId6HTDiz4qf5KbU0P m7pVsENsIg5d2p4UVWLN+li3njni3QdKdeVRm9Ahabp1yWGwkizPj7qUt6PbDoJoLtTjfd2YytTd ApF7Fao1HLxHUO8L5XvfeYm/r+B4mSPkuooLffi9BuJGhi5tot9TgJWT+A4iaS6M6L5pg9Ej21LQ vKw1TcvKd0M9oL+p6BHd5PYAPXMXt4xumgjZHsXBXOzUQgJ0/3hV6n73lOd8LX5vD6ovvc0eRsLE kz9BvkuKnkCXE3zteTZ4KhNDIeNCj1n+QMMJNiVuN2zVFS1UcH7iZ3u3JQzIx34LlXGmhA7vlRXD gn/RkfVeOCF0y4R/fYZyHfUjapJ2+6R2bsZuCFdtDRFGqyRrMRdTKlV8iaF+n8eAjxRJhwIYfkc6 fleDOVhQODhF+FMEPJEbXLB9EGdLMXM4DWRQMLeEmwdzgkNTs4VdXLB+MliFz5Bh2VRw5MdhWbUF CbcKX1EYkldrBweDVniG0aAAP2FQ6AF5hDGAZch7byeFYmh1K4ItWkCFaLiHqECEnPBV/VeEcNiC ivWF1lYeeDiFMciHjJgKkLdK+xR5cDaIB9hAQ0YatxYGetiInLgGQQAAIfkEBQYAIAAsCQAAAMUB PAAABv/AgnA4NCSOyIdyyWw6n9ColGkwEK/YrHbL7Xq/4LB4TC6bz+i0es1uexXVeNVBrzum+Chl z9/jq26BgoOEhYaHiImKZ3Byc3Z0eZJMfXxSR0pxCoucnZ6foKGino1ykJOolX5QDkeOcpujsrO0 tba3gqVxdqiSqhRPrUavxLjGx8jJyqSvp716lU9ICcTVgMvY2drbYgp+Zkts1I53kc9Ov02t09bt Cdzw8fLLD3yx3fUP4s135+h96oa1GyhnnsGDCD3VU6Xvy8JoacaZ8kcp2hIHBDMWS8gRDbCO2u5h 8ZZOiQKRWB4CVBLxFUWVq5RgjCNRY0aUIIkoaJhzyIX/ntjyXYG5B2c9lDsZuqlZxZ9FmTNtSnUE FMueqgWugqGA9RNRVTiH/FIaiKmBXgxlTl1LLGzOnVh/glEgt2unr9+64P34ZWc4L818PaXDdiAm s1Ttdq0Xhq5irw95esHrdmi6LoGnpH0QtTDBBEoQX3sMlG/fuqRFSb5C0uLJk1y+LqlcIPOTzRhF e7a2pNq7MFyJrAZGQeTwv0JgD2Gspd6F53w/UrjAVWvxK6anQ8eedfqWPc+pY5+eV4gf7cHDB7cs nGtkseSDo1+fGhFJnknBjgRm/HIY2xWt1NluUo0T2kZbSYbaAz9pZZ6CStDnYHdbXPDAa8xZEot1 9BVw/8GGxZ3kIF1HfcdfUrEs9Np0PPnxGnUhkmSVZAtdmFRDO324CYMX8ljfImP1UVlrQa72BYAw XUTgWgOe9YBZYjCXlXjmpbcclRRmxdNzV5qoBYtEaMVgmMFJWWVyWGbBoFsTZjllmBZ2eQVqBfgI 3xCOnSmEkT8aghefVo0FKGCOLJFWk0sSFCEFA/YGixh1EefThg3Z86CeNeqZEp1kjnenEHF295qI wdFFW5vLdXipm3WiZmqn7c2Iplih9qkQE2RERhuhciTJGaKJtkPJcw84Alqxj27lXnX6OMhcg+6h JhcwzwI65pfDrceclOF1y2UBeVYIKKpZTngtmiJxav/mquFOaZqtP7oUE2HBatTPot0i26u+Veya qpZ1MksEtKCySq18EW5xrqywXmparSNxOue4qpZL38Kv7qnqugCDS6dzFcNrl0tQ1WtTP3eA5y11 JNfkb5V1UUenJTDTyEeV5O4p8aqfamxmzh53kTPHHZvr6odiGckxX+02LPJjxNBrcjOF/uocdHx0 S0HLyQqNJXlDYcmgqt+CunPP2GU754RtatX0puKyp2mrOiEdsJoQhxuuZEA/3VPUUw/Uj5PzqaIe Mcd2zYXdHuP07rtzt70gxAh7CmegtOLIKdvX7dnQ2JmjjbHdkGvM10J4RroexH53FbhU5ZwFXpDQ 8fv/yrES+dthxburSeNqS2vN89zmZaEddXxjDqd6Ih2/+8W9gxsyY85zR+t2rXelQE3ABtvok6DN HqQfGh1YxW/KvOaG+owMmcbQpb6sXCGzHeQXPIi58vpEM4E8PjDdq4b5RpO9WoTsbrSIzHtQ96WQ la47ZJGeA3+Bp/PAL4IB04dQmrMspchGJ7dDgskGFLuFwGh8tivQkwpSwKAcsBPluRMDjTdBGuIn LzKiYSzY540bclBCzvpIDmmYweQoZ4YQHEL+9Be4TKQMaygUXAqNlYk4tJAeLwTSA+skQS+lpCiB EkkOh2g55b2hbaeLzhavs0HLZKshcaCCQOaQqBKK/w+FAexVRqrYrysiAy6jQGIWyFjGMAlSVJYj JNqcxgVCbvCR5NrWA9vos5M0BVmZYOKSnHi1/wHjdYnThB9HCZ9d9dCLsUIVGGGlSOItcguOTGOL ePe5SUIuH9tryr6MUBOz6CaOGDHhCYu0vziu8Hyk9OMh9zMoVfpsPGJ0W86m2bcKPi9VPKGk9LA5 SMhdJZdSuyQvreGKXz5xmILKY/kUdUwCJtNvy2RNUUY1qjZJCY33QCI1d5hPmjVyROWhJBq5CS7l nDI5YHTFFDNJThG2Iz5RFJY6d6FO0NTkndm7WReIFCTs3GOVOANIIckEEYT6s5slJWiVmtdPVZhU pP9CcAWwOKNJOUyjpoWKqKJe104rYPRpGv1nM+nTQ0NxblFETCos+6AFktznizbTFvT41MOn4gkO 3SvWEm/6S9kUUyqcYeFPbRVPnWzRYNQyKpk2EVSTNrAvMbSmBFGiTQe9S5sI1QchdUEMhhqLq7+U nR8mmig+8oZfYyVrNaU31DBBtZRVkkwrWSW0iuVQkNrcYIfwyljTXSGwWjXFOAE7kClO5Q6wy2Mo 3ZnYx4C0qUCzK+/WA9LyTHaxr+wiztqzGhmti7MHTaISFaVJwLIjsJs07W4M29r6lNWtbzVPWPIC 0hneNouMhG5kVQqfEvFWTY8zDXLBJ5EngY+XN13/i2G/OseqKa65XYnrcnSbVKLp9rUMvG43LRMW MloVrw95rIBNusM9ztG85zUuez0TwAG+DL4IsRQ3y2qdobLVm9+MyV80zJgZcjZgmwUjZ+VriSaA 2DKlMnB5W0FeBd9uauEUXEbukDsIK+aDnY3uC4XiXWte2KUQrITpTsrMx3KWaB8Mbs9mfN6mgCY3 1HBxMR1lsnY+2MZYviJyzzLOszw5hOkFq3IXTJN2oi/LaMYoXwWYm0v+KspwFuGWyUHmPUrkzGnO sx+3rFVq3EsY6D0uTutMzvXezsx6TrSWVaxQtdg0zuxgr6H7+snP9FTRmF5Of4eCKzyZ2HPImS+4 /5yQIibks9NcrFOnUQ2uGZ+PGhfRH6RJC9apmJawArxophX9wMdRSmOwEtPucGQwvlWqUvLR044+ 91nCNjqs7TXuoEu7m/BVujCX3rWeS0dGqSLQkN/uHH2/vTS27jDZHSteU13NSyWBeRhhXjBRxmyY bGsbzaVrVouSlu5/MccbwslKP/ntqc5laHhnNUAehZGAPzu0l1K2ab1qZO1rswU0ibk3lvMd7ggd ez8ZNImnyU1b8GoJOWVKqwT5hNyZHMvRDaW1sfaYVT8ci3yv0/jGgWeoDW3ilNxe1m8N9S91s4c4 EhqeZ7HAZWtEhQmIKuesHSpm3ljC2vReks4hfP/LT3k73+5p1sUIfk/HVYet++63Y7HgZ6cngQlU hzNNAi3nPdI7HXXeenPvmrys+FtVH8nQ5+4B8HAD3tzhVrpYtIDxatDLCUwprrQR1yvCAoTQrNU7 KR+XNoGvylzyKdV1hl1scHfs4KzCUcjgcGuthgYTKxy01Lm6XPdi3oqax2gTADnyT4MaOSzxHO89 p2pO129Pp061iVnN9qaTA5Ovx51h6E71AuH89ojLvfbnsVpjuvnVk360tOfcFItjP/vbT39InOTe e7264U2eu0BmH+nz1wvP6s+/MWDdhK0pnMroFXszJ35xZn9Tg3/6l4C04GdN4Gb6Emdm5hukRX4J BpgRCniBixAEACH5BAUGACAALAkAAADFATwAAAb/wIJwOEwojsikcslsIh/QqHTqfCiMxKx2y+16 v+CweEwum8/otHrNbrvf4YR87lRO7/i8XpqMyuGAgYKDhIWGh4iJagZzcnUKe5GSeE1WBgaKmZqb nJ2en5wKjI2Vk6aSTI1zl6Ctrq+wsbKDoqpLp7h5qaqqrLO/wMHCw5q1pHa5yUu8zKsJxNDR0tNm UWiQb8Z0kNzJp7vN4QYK1OXm58SQUGhQ5G3ajurek8vh9quY6Pr7/Jq6Yv/UwDMyD5WSewgbMerH cM26hv10HQETac3AgnrqJdwoJx/ELu4+DqEgElq7LPIoWNPyMAslOPDkYYxykKO9S6NyPiuZhQJJ /54tKfLsdEflA6MPvNALFHNmu5o2b+Ic1THk0AJWP/4Us/VqJplUwID1qTKr0pNgElAlWFBjVGZJ OuJ05tVrUDBd6yqSabYLFJ9TAOb5opbUPKhv7R1pp3ZqY71DKfTtkhdyp8lCoiC1MgRzAYmeCxSm kwtx4o3cGl+qSiYpEddDksIWkpWmF2x+yUrOTO6obNezM8M+CtjlZ5+5yQYnXva17OIFdG9R0BWb vJB/HzIPbtkQWtqaV7Lk/nLMaEffkJxOfEWd6rmtrVYnGXT3SCFd63MfORx4UO3BbaVSbF1Jtl9s s802YGb5LRhdS3d9luBRndmH1VZH9WZhd4dI8v/FZpt9Z95aYFGi3npRXeGIHIxN5VEYuB3XH34V YvhTgQVSdiCFzt2HoHA9webgdJXx55KNr82nRV4ZJkkEkhxyklEYU57BSyRxoXiPiugxZgR6V0wV Wk/8CRibO38ZKaFwAFLm13JCCunOkMf5+KabS6KZYF5MLleZhVBGGYptZci0xpUmHqElQlyOpZIt ULzXWlLURadhZ67Rl+mT+B1x42Q8bnFXS5VeOJJu0tHoBZ0/jgckgWRy6hJ5QibJmaCCIsrHiYuG 02g7f+n2AKJyvYiXpaZuqCmN/3naaamiFvlqq50ii9+BqurIRYRrdstgrNNSS21ekCCHK4e6Ztn/ a0LcqIOqcoiG6UsYKgkYqnAY3ovVSlKAJK234a5TILbRfXggtE/q6aSs2S6csJ1BntsdL6atS4dh Vrj7rrAUW6EaQA76tuRW1P2Jo8HbwtnTkPq29O+3XGxoasB8VhjtkgzPKrFlcHFpMSmGPbHxxsN2 LK+xeEKs5rWuiltnhQmGC/DTTw6X48o9duYOdVZnDbOdt846MMMOsrozT4yo6PPPF5O2GHMhClt0 OJHiNOZyoho3HRET8c0dqsDVRl60ZFlF65GpEkiWzpjqXbCoSQnr+HHQnT3UEXPx+rPmfWxXFGBz 3xNpY2NaLuWOBF/W9z6rS7N22mv3qqjbb4OO/4dRsW/p8SWlm54Jttxe9o86d0IO+R2Goy4Fy4FN NxiCvQW/r4TI74tHFr5uDmntthc1OkJrgdnYTr4PI70/Yf9IfMrsj5c8dqj7ZTgX67MJvdQ9iuf3 hLA12kzu62mXxiaxJQC67WPlE8b5FCE9hbVvVvuJEIR2JK0Fek04esrgtjDoPDi5Yw5SgMtGwrc9 jYWIEqhJyO7mlcBf9K4Q+nsgS4rUL8Z5LXj6ctpZUAKgrXGrhx2E4OwgwZbYGdAZPXuC5/awKBIm oG68a6EUH0Ql4FVmHRI8HP6+ZkOKBIcbHORiq0R0QQmph4gHZJQIQci9E+LBYquBlGpeOEW91P9v h9u6Yhh1OME8pix1Tpsg/MzSv/RhSmWKmh1pKMbINbJFOVhqJEfQ2BG4FG01dTRdDGXYxelJLShc KyOsOmjB/4RNRKMq5H7u+JBEWlKSRlCkLUDoRuTZw2OoOaL4MJnJnW3yeHmg04QgyIdOImh5yfvl MWt4P6dV53rWax5W2tMMXP5PXUBjUSQ2ErrEkDA1vOwlrpRpzFEuUx49uqMOxQjMO5HRjPtrHKb6 QjwRudKSBqzYirT5RrY1gxFzUcUKySdODpFTlOak3hTy4x8tzlAw8ZsaPG9oFTBqYX0R+tI1faVP gfLBn/8blk6uJC+CFhQy6uSkwx7nnBnZD6H/VMNLRNVJRrT0iZ4ACo5Gq7m29jRBd4uiJLt0+cSj nZRDZmvazbYYsgklz4+CeaD+3olFDwbxpbQ5olBjecaOsu173vymSFl4VLuUEni1gpwDwTPMpVZR huKhqhVohVOndgYh1oxHHf53S6KyTawILGtdlLnWpkmvTS1dZ0xfwxJQBehW70TnrOpqQ6LKsqiP 4CtIU4REwwRWsFeJoTVSqqbD+kdwp1XitTI2WlIlVZ0YNeS1CPkU29C0JTvl6TEeAUC/2kSWTmwb UO0GWq+U6JRozcxtOPPDhjbveWDxTBYpJVuJRrOYEsWtLmUpwBN11LfcBKtmmRHHRRK3uOg9/+pl mZExNi7DLdmsZl43O77ygum86c1vHampGGry9rv9pa9cFBI+cI5DvwiW4npt4dNU7NWRm7UvpELn xBXSMcEYvsqCGdwHdTlhvOvKa3DdE9xGWDjDKMYKQBZTGxbPM0LwY2a7EuRi5V43q4bc8Da4+hSf PTgq890SiN9y4hQnuLkMg2xbESsuU2ZNyTZuFm1Qst0GC5DD4LBJN1MUwvUM1MgIru5/1Eee6MWm i32MVdQ+EzCQ6DiWes2YET8sYIxNQTGiE0U4wVxc2coGO2eSKDYgxNi2Wit/YwwYtnLbMx5rbhs/ hbCWriOTSavGpHw+qmzJESNgZaovy4rRlP/TzGZX1fbMCtXgRd+cyLdtmM6S1m1Ia+uHoL4H05kW pyE9jerPkENmzEqTc+pHaFOzEn+kZTSDedzea0YaliSlG00qfR4UuWghudZ0bRINHkH/BmAudZnx Po1qHE5Hx62edn+fPUti3bKfcLz2gbNd0PS17ieF9ORrzGwtvHkrQvjutX82eO7e+rTHWoV1u+MR 3lr3yjHFwi+96zhmRL/Kyf+2caAxfnEHDlzgXXjiRlnM1YSzO75CNjF47yHhnFz7whM36FwpxRIz 2pu1IVmddXg4TR4uhrEbZ2tVz7eYRrPYyuvOMsotKd46rwagYoq51M1R9N0WUW2PxjJ8hdtSsS1b u8S8cLnEp072YTwxdKlRR1ywSTGFLz3CURF71MtO92BcgSY0YYvHWs1qt3O9zjaJ48vrTvhZtOej rsZ6yQu4dcAnhCpQl7eLYF74yp8hCAAh+QQFBgAgACwJAAAAxQE8AAAG/8CCcDhUGI/IpHLJbDqf CqJ0Sq1ar9isdsvter/gsHhMLpvP6C10zW6z0/C4fE6v2+/4/NjN7/f1gIGCg4SFhoR+iYpOh42O j5CRknSLlZZGk5mam5ydg5egip6jpKWmX5iPoat8p66vsKRHYlForLdvsbq7vIJLXb9luMNPvcZk tce9wVzMwsTQSsrTXg/UslTORMlS0nDR4EjXUwrW417c54BQV2tz4fDq8kPmW/Xzek1qTJTw8fjn 0mG5BzBfqmba2nlT6A9cwWsCBz7stHBfEosNoaHDEiUiGI9Cyj14ILBcyFogQ44k2U3llZUsu8XM NrIWzCoeZxUpl0pkyv+J30pW3JZtaJaM4YBJIUgw5FKnVlISRFmAW8909Q4eLNCUnFUiTLfdm1rS K9in9NICxcOOoT5USKNtVAuVK9ivdumNjZqTLN266bjNrNK1LlGXZxMr/itkL+K1gfhpefsxrsYu 9axlLsI5K068VApXDZxMMGeZjM0SDr0TbWrWrvM2hvxK5x7LfWq6a8a59OGwaqnKhp1N9ey6MJO/ Xkyu+MnYw6MbNnyPJ+21uN0kz6Wmam+0Ng2Hzyta+ultpr0vX38cZ9HnzKc6P9y+yMjrD7OvSb6S exbNacnnWVNbbUVcc90ENtxP5am32hRZYRVbYU05BiF+BennBH/b7ab/BXBLCSbQfXpJ5F6CIV6I Hnv1QdeegSA66KKFKGI4j4ZL9HcEf23Y42J0XRU44o8ywsccV6XRaORoVsQIo2sgbQXiQQ3aaAyO O+qGBElaujFZS3WMeJMZIg1W5HRc9SdTTUeBaZ5TY9JXlZpWBoSlT0x0+UedpvzEZ3536rklKH9C kpKf61xVWpQ5fTaUgTtVhIltXl3k5k8oLZRQoCT5UyhFqkR0FV+fvbdia6bOhyaqJ4EGKaqMoreo foL+82kmiN7xao2p8nrqr7sGmyuTvzq4q7FRGZedjrjd6iyix77akVDK5mQtQgiK1+iqq86aEbP6 OVvosXIaZ+6SRgpb/+o+2coobbnwGtsQuFiKyye55/UK2LnE9uurrOwWq2C7Uao2b6312msjvugW Cxhpvqrr6GRWDczqkgUDC0+nd0qmMG2U8lWMnAZuaq2lkWKKcrklJ4jyox0n/DFQIZ+4br6Ujspv w5XGGqy5FiMobcw4zowdtAo5LOTFPPub9Lrv8lqWzZASLbPRADF8psCqakWtvk9X2+55U3dNmtUa Yp0htLHy7LXS1wZcbdCwjk2ykGinrTY+DEfrW6olV3zzUXGjK2pHqrqJcd5F7y1P321vDV/Viw4O b+QYT2x3voszHq7j6tRcOdRPU56p5adz/m+/hUfMNOue6w26nSsfKvZcst1m6o3HKydONu4927bt aLF/Pvvx9hbfOPLMf6q87M1Hv/DzxktvPcjUZ3f99kdn3yz3zA+/L+epFwkx+WQLpzXx3lsGPvKt 41X230yDdpr809nevvvvg57x+OJDk8UO5y6o0M1l++Nf/7B2qPupzoAcoU+jREU+RiUwLgtUWwMB eCLE2QxZxZnWYVqXsgtmJINGs514JCe4rj1wUiuUHAtNiEEUKgxTMZwft0DoNPXQ73abYx8NG2LD 5CnOh+kDk1byh7NLjbBpFhwiEYtIxVNIsYZVzKInrogULXqRE1w84RfHKIkwTpGMaDyEGc+YxjbC IQgAIfkEBQYAIAAsCgAAAMQBPAAABunAgnBILBqPyKRyyWw6n9CodEqtWq/YrHbL7Xq/4LB4TC6b z+i0es1uu9/wuHxOr9vv+Lx+z+/7/4CBgoOEhYaHiImKi4yNjo+QkZKTlJWWl5iZmpucnZ6foKGi o6SlpqeoqaqrrK2ur7CxsrO0tba3uLm6u7y9vr/AwcLDxMXGx8jJysvMzc7P0NHS09TV1tfY2drb 3N3e3+Dh4uPk5ebn6Onq6+zt7u/w8fLz9PX29/j5+vv8/f7/AAMKHEiwoMGDCBMqXMiwocOHECNK nEixosWLGDNq3Mixo8ePIEOKHEmypMmTKDkFAQA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/spacer.gif R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAQAICRAEAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/misc/arrowTtrim.gif R0lGODlhBAAJAIABAGZmZv///yH5BAEAAAEALAAAAAAEAAkAAAIKjAMHidsLm2HHFAA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/toc/free.gif R0lGODlhIAAHAIABANYTNP///yH5BAEAAAEALAAAAAAgAAcAQAIjjI+pqwDpTAzzVPjQ3Nl2Boah Q0pkd2YpVq1mW2IypZ5vVQAAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/toc/rarrow.gif R0lGODdhCgAVALMAAP///wAzZgAzmQU3m+7x+ClUfx1Kdx1Kpfz9/evw9ilTfi5Ygh9MpQo7nQAA AAAAACwAAAAACgAVAEAEQBDISY0IdxQibdDcZIBUd52fkixhCbCu+W0VmqnenSDISMdAxq90mLUk xcwwiTECmKjGApraMQcqHqJIogiPkwgAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/toc/uarrow.gif R0lGODdhCwAJAKIAAP///wAzmQAzZgk6nYaetr7L2N/l7AAAACwAAAAACwAJAEADFgi63M5liEAe MC7OTa2NVaMFUzhyZQIAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/toc/dot.gif R0lGODlhCwAJAIAAAP///0JCSiH5BAAAAAAALAAAAAALAAkAQAIMhI+pGb2PWoC0yooKADs= ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/toc/darrow.gif R0lGODdhCwAJAKIAAP///wAzmQAzZoaez77L5Qk6a9/l8gAAACwAAAAACwAJAEADFwi63GCOlCAo HS4reXWcVdgBXIg10qkkADs= ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/math/agr.gif R0lGODlhCAAGAMIAAAAAACQkJElJSW1tbZKSkra2ttvb2////yH5BAEAAAcALAAAAAAIAAYAQAMZ eEchaoIcQ8AcboKhAieCEQDFQ16eMQRHAgA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/math/gamma.gif R0lGODlhCQALAOMAAAAAAJ2dnYmJiU1NTRkZGWhoaP///0JCQiwsLAAAAAAAAAAAAAAAAAAAAAAA AAAAACH5BAEAAAYALAAAAAAJAAsAAAQf0AQCjpEinFKQMAV4XYM4Xtw5pir4tWVrIPIss+p7RQA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://humrep.oxfordjournals.org/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAAAEogQZyUnFoxUikQIL1KrFJSUv/2/xBBGMV7vcXNzc2Lxb29vZRzlEoY QZxznKx7pBCLOc1zvb29xRicQQgpCAhBGEFBQfbe9v/e9jkpOc2LzZyLnBB7ObS0vaxKnBiUQRBS ICC0St6s1c2DxUFBSgAYAN6s3gggCKRzpEpKSghSIO7N5sWDvYt7lCC0UlopUgAgCLS9vQhKIIOD g8V7xZxqlBBzMRBSKUEgOWJiYkpKUubF5ggxEMVzvWJqaoMxc5SLnIMxezlBQSCsSqy0tGpqcwgY AMVqtBBqMcVzxaysrHuDgwgpEKQ5lAg5GFpaWr1qtL1ztAgQAFpiYnt7e817xWoxYhikSoODi+7F 5hBKIJSDlHNzcxBiMXNze7Q5nEEpOaystIuLi3MxaikgIIuUlIuDlKR7pAAQAHt7g6xSnFJSWnMx YhgIEOa95hgIGLRSpFIpSjG9SmJiar1arAgQCKxzpKSsrGIxWgggECAQIKxKpAAQCDEgKc1zxb1i rLRarFIpUpSDnFIpQea03rRSrFopWoOLi0opQUEYQTkgMUEgQRBaKSC9SnN7eykgKWIxYpSUlJyD nBiLQXMxc5SUnJw5i6SstLRKpJScnJSclLRKrJykpHsxcwgYCJycnKx7rJw5lJQ5i71atIs5ezEg McVqvTkgOUopSpQ5gwAIAIuLlOas3tWUzQAYCL1KtFpaYqScpKRBlEEpQWoxapxBlKw5nJScpGIp WoM5e6SkpIM5c6SkrKxSpCkxMZR7lL1itJycpKQ5nIM5g4sxe96k1TkYMVoxWpyUpGpzc5Q5lFIg UouUnL1SrCAIINWU1axBnKRBnIs5g5yLpJykrNWLxXs5c9WLzTExMbRBpLRBnLRBrKxBpL1BrLQ5 pBisSgAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAI/gBdCRxI sKDBgwgTKiR4q6HDhxAjSpxIseJDbRgzatzIsaPHjxoNiawjMtO2jaJGaZOmKhrIlzA5ZkISLJiP YFEMndQYKZG3aaZcxhwKM5rRozt5poIFNNqoWbNUaVM1ipc0XaK0zbpWSquqabqSEh0ayU+uVKa6 0bqmK0c3DXJQEUqUiJscMrR0TYOUB5LKsUQj5Rh1JS0tXroYdVskJBeMaai0XSqlgQzQbqiEAA6c 6qfha2RQLZ6WKxcx0YnIhPF0GrPmzTGvyPm5qNshVHJodQszLU+eaWGkLcqzyNM0t7xhx7Q1TZS0 rNGmzcoqKhrUaNRHOcfeTZU0mNtm/gklSmaRoEROlCeaBtKTtGipLgGOlKrAoiveUrqEqtK6NGnd ZaXVKJlFA6AtLl2i0iiQlOKUS6JM49Iw0ozyXUeRhKELLQqmEokc0WgAQ3GiLJKILjDIBoRwA0Ay TSVyLCaKLnIIgownkFwhymDTpCKbNnLIkYMcHkViihxhdJMHLWQcIo0p01yRyjJllCIKJNLUcuIi 0UBJRirdmCJKIm3M4p4p4pkyihx5dAPJmL+JhmEq3CyiSx6dedOlKm0EMEptV0pDRiLX1OalHNK8 mQgM3ngziylORLPIKD5248coiRgnJ0d5+CRHLgySMUqXuYRxxShB7XaNILVceUUZ/mD5kUcZM5bh iYWmkPHkKJ6k0lY3mULWTUeXsDeKsZZJ2oYnBuqynye6DKvLtOIZJ6E205AhVbbSTPOdLp5k1Vy3 RHnDzWKjeIMRNxlxw6427r6r7rvaqAvvvOvSC1I00/br751s/SvwwAQX7C97GnUDYDcK/9dNNAwb xXDD7x1l8cUXRzzxwwZC/DDDG0UjxLTHjjItW85NQ8w00/DqySxjiVIKWMToBZYu1whRDFgsD5vR w9LMUrF/Ff/3n4HvjYV00E6I4sQwTszSghROVC2Kz8plnRESfyjhgwQkZICBFRJYgQTWWmftDCnO 1EFKHVrwEEwdc6dt98XbcJLJ/i1H2e23RtGI9ffghBdu+OGIJ6744ow37vjjkEcu+eSOfwPGN5Zj rjnmGH2jjeeeN85HCmiEggYaEEBw+upokN766zY8cEc0zChi++245667A+l95IswneBRDR549NJL 8Z0kD7zymjTfiQAfuAHA9NRXb/31APzlkS+9dLKL8cUb330vwBvfiTCWCCMMKINEAwf28GOvfUfc 91IN+OLn/z3553diCSsucF/8Bki9+XHkd+W7n/F20Qnz7cISbLgAFFihCTMgIoDvI+AADbgRBO4P ed/Dw/5U8AsqdIEOrEhh+zJ4vVW4sHqvaMIqqsdBjfiigclDXgPFsAQR6qAE/nSIhQm7IIlmrLCF LkziDGdACQrcQA8FBEn9hLGL7+0CD0sQAxYtYYQu7gAKRqiCGVjBBQFWz4VpWEUa0viKHoDAESIA RxJmmD0pymJ84CNe8cQghiz84Atd+EIVusAKMxyRemhcox3ssIoe3AALc5iDCCLwiunVMCO+kEUI u3ABFYzhex6QwQR6oYYsMEENX1CDGTQRBDNOL5GLnMIUKuAFCkRykn2wpB2NR4dsxEIFUDBDEWSg AAYsQRhZGIMamCCJ5nHAlWpEAQo+8Qk7yPIIn7jBCxxBhEZE0XfGk8QQHvEFHdDhB3gQgwyKgIdO aMISzYsnNVz5iSeEAAdN/qDmFNa4ihgkoQMroGMdfSeMXoyBCmqIhQFiAQU1gEIMRcCE97p3PmHg ghofyGAjt+CFJMygmvxUovUuiRFfJKMTkuiCMhiqAmWYwRJFYIIl2qk8UDSvlRlMQw9C4AUvbAEF aRTp9Uiqjd81EBFM6MIPqFAFS+wCmeZT3zst0QycvrIHWwhBI2ZwhCQCQKAjlaL6yMcKGnwhC1DQ QQO7J1VNNMMScLXq9NpoAQSgQIO6JOhTQfE/VuzCDFWoAlv5CldLmGGVz2ThV02QBrzmdXtS3YQm 1Je+XjBQGO9sZgVZAc9DOnaoIFkDPOEZz+bBk4JUnapbDXsGV36WhiD5/sAgJkFbLsyWtrWl7W0n MYhBAMMFDYjGMZ6xh+Ia97jIRS4BBPSRjW0MI86NLsg4hrHqVpdy2M2udrfL3e5697vgDa94x+uR bWwDKeDNhHrXCzmjfGQbhvCBFjCgBS24YjyMQ8IpPhINQxRiBCM4wBuCcQvzGhgjgTNvgs2rDQUL 7iXwhYYrnIHfjESjDoVohTVYwANDAAIQdaAbKQJBirl9eG4jrkkwSlyHmJw3GrfIxAI2sLfA4Tca zsDGCIyhBWNoIw6GWK+Q1RvkIWdCb4aIiTNUDIhgnCIQc3OGMwC3ZFcU4gRIaPBJDqxlLRv4ywyG SR2Q4IMa+OAUVvBBIALMFoyNZCIQgSBJkhe3jW6sF8hEfhhHLua4Ly94IwEBADs= ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/searchall/journals/humrep.gif R0lGODdhwgEQAMQAAMwAGP////G6wOaAjNg7Td5YaNpDVeFpd/77+9IcMfbQ1frn6c4LIu+vt/fa 3tMjOOR4hc0EHM8RJ/3z9P33+O2kreucpeiLlvTGzPzu8NUuQumTndc4S/K/xdYzRtc3SiwAAAAA wgEQAEAF/yAgjmRpnmiqrmzrvnAsz3Rt33iu73xfB4GKsAIEEAKdkSEgAAwCg0dmAygCHAEDgHgR FSEBhXUEHEwmGmPAMWhrBQHLAPJQOyxrBmARIJDgB0dNIgcBDQBwWiIYfQ0BEClwfiKShYMiHAEL iAEcHwgZWJM+pKWmp6ipqjxjVQFql4JOmgkiFwivIgVACiRAFWS5wUBQasRxnMQTBkfECIoHGbhA ArXNxBkFlH0jkgAaYsQUCXDHQA/e5M4ZB9sOepyjq/P09fb3+Pn6+/z9/v8AAwocSLCgwYMIE55o VUSWCFlPJhg6YyUBqF2HvGh65qpEkSWbHHbrE+GCIUERnv8cYtROBAM+zJiMwEPF2zYCJi+JiDBy lCSQ8CIUwsCJDySbCpMqXWqPYa4NASh0wDKhzpMBvl4REdBmAJZ2VhiE8/hKAoUAGo6waaMNKSwA QCWImSBADIJ2agdcwPIOwAOJDjqctQAggqMAGATw8cntJoADuBQIkKhAj008jZlq3sy5s+fPoEOL Hk26tOnTqGm0IbE6wQBtIlxrMzCAw4gIELDudMMaAjwnukd0HaDI9XBtBbrSAWB8Tp0REpIf8DCi +WsJI5LX0jVgO9wD1wEkH94mevcRHsAXwM79ufjzqePL5+f07UOZT8Iw2DXGEcxhLbXS0RIT2NdT SSfhZwj/XAEgMAABBTBClCwMHEABAmkgJUkCfAhQAAcHdOCehtwwosCHA+DyBhAZuTXfizCmYg4x BkIUwAXh8CcCGBYwcOF2QBiAwAIJCHgMBdpcU0YyQFAQEzEL1IGLe1s8ItIuTZBIgAB3RZKZJGAA M8IDDXJSAEwuxqjmmjrUJwECFNQRARezYKUBTx8BsYADGWiihxVEGPmKJQY6NoIsjkACFQbs7TKO Qwx8BYBJhH2DAALRBTDBBzsV4J2WCZwFmwSM1MRNIUDIw+aqrMpQX2EQKABKA9TVmZVZAbhXSC9j /CWMRiLgYYGSMrnlEBbaMDCAGBk0MImSClzA3jcN8KHAKAA8FXaAAmdh4FtP4BrRQJ8KfBuPS2Ko 2uq67Lbr7rvwxivvvPS6GwIAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/search/homelink.gif R0lGODlhMQAQAJECAAAAANYTNP///wAAACH5BAEAAAIALAAAAAAxABAAQAJQlI+py80BwwG0AkPn FbZj64TiSJbmiaYOlGTfC1fa5jYsUrs5TcebCgwKh0SgpPXbyWCaD0gRwSV5TY7sWXvcmLrp60pd KXYzstS5LKrXqAIAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/portal_imgs/search_result.gif R0lGODdhOwBQAPfXAAAQc/b////29vb29vb27vb2///2/////+72/3t7e3tzc3tze3Nzc3Nze6y0 zay01bS0vbS0rLS0tLSsrLSstKysrKyspKystL20tN7V1dXVzdXV1dXNzdXNxdXN1c3V5s3V3s3N zc3Nxc3N1c3V7u7m5ubm7ubm5ubm9ubm3ube3ube5t7m7t7e3t7e1d7e7t7m9tXe5tXe7tXm7s3e 5sXe5s3e7vbu7u7u9u7u7u7u/+7u5ubu9ubu7ubu/7TF3rTF1azF1azF3rTF5nOcvXOcxXucxXuU vXOUvWqUvWKUvXuUxcW9vb29xb29vb29zb29tJyUi5SUi5SUlJSLi4uLi4OUvcXV5sXV3r3V5sXN 3r3N3r3N1b3N5sXN5pSszZSsxYuszZSs1TFzpDFqnDFqpClqnCBinClinP//9hg5gxgxgwgxgwg5 gwAxewAxgwA5g83Fxc3FvWqLtGqDtGqLvWKLtGKDtGKLvVKDrFKDtFqDtJyclJycnKS01aS0zZy0 zZy01ZysxZys1bS91ay91ay93qS91aS9zaS93py9zZy91UpKSlJKSkp7rEFzpEFzrEF7pAAgcwAp e4OcvYOcxYukxYukzYOkxYOkzb3F3sXFvcXFxQhSiwhKixBKiwBBiwhBi2piYmJiYmJaWqykrKyk pKyknIODg4ODi2J7rBhalBBalHNqampqYkpBQWpqaikgIHNqc1paYiBalKSkpGJ7tIuDg6yktGpi ahBSlMXFzZSkxYucxQApgwAge1pzrFJSUrS93qS03qScnHuLvc3FzRg5iwAYczlzpJS01cXV7pyU lMW9xUE5OXukxbTN5vbu9u7m7t7V3rS0xYN7e+729gAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAI/wAPCBxI sKDBgwgTKlzIsKHDhxAjGhQQZ1MIDidKxBHByUmLHComiJBI8iCBHTtyHEhzckeJAWnSDBhQsqbN mzhLCqiZY2fOgxmYVasVccCpKVMSkKL5k2CuHgc2QBwwyslAPieaEmxU4cCJCaYkTOAUdsAGnydU HjDFoOAGYkxCEBNYIcSBAZswqIW4KVapATluSTgRIRXNVkQPwOIkUFSVgk4WHFAxSiCqrqYo3CUZ J5aEA1EYc5IllVnlHKIgNEZVMESrDCdkCZzyuUUwqSUxMDoghcmBTQ023MBwiwKnUlMEQnFmgKAI Bi1iz/58QESwrAvTEDwx4kAIWAeoWP91kupAiT4nXjlxPXDULOycMCg4sKPygVumJh9gxhhiDldU VJGVFJ9x0ooFTMw1WA6oMHUAMaIooEA1HCgQAScKTBAHMVRAQcwEvpFUgk0zMeTgVDbY8MGKLLbY 4hUwWqOVQojc0QslleBYyRGW9Oijj2DMEQZCKszkE00DECDQAALkkMOJBGk3kCLLFDTDQh98gZAI GWQQBwdxhBBHCxpoEEIGLqiAEUJSCoTIFQLJcAAPQyzjhRdhBGCQFloedEIKM91ww0wE3JDWSznc 4JAiWQhkyBWHhPHFD5cYYYM1PBCU5UFpiODEBhxwcJELcrjggggitMBBB4t2EWcSjoT/EYgYiSBR SRdd4HAAAgVsOiNCiKyojCZ2JJEEJpUYcgkeNnjBQyGJdAHCkL8eFMQXdSSDhK1ifHGJEJg8kskh QhhSBAm+VltQIUfkgYQdRRjxhRiXGGJEMpn8UAcJYUBTSJ/VtnnAIVoc8ogZjogRiCFDyOuIHlfw 8MUVlfyrrkGHfAAEGXgQEYgShgjhRyCOOBKIF4b8wEMM1F480CFYsBBJEnl8gYm3fiARiSNJDIID CQfQ0LLLBxSyxQGW4JGEzZmE/EMSe/jgwyUwHPDB0C4fcjQOROiRSRGVJHKFH4ZE8oUhNgh0NdED GR1nHc/ImgilXdhBBsA0XMK2QG4T/yTEpImI8e4iaaut9959C7RFIJbIG8YeSRjBwkB571300QJZ Y4QRelwyiB92XCLnQDYcznbiB7BwhRF1uHtI1QTFYDrRhVRZEA+GiOHHQSbM7nIhwFgh/BHEC0+H LVYQT3wxVqhSieVBICO99ABMb/31ABgB/S+TdO/99+C/8cYv2u8NBPjooz9++WyfP4kv6au/vuVA cP8997/kr3/+3UvCPtH1mwQb1LCGAhrQgGpI4DGOsYY9aOIHPyBEIQghjAkW4oIYzGAGM9YQLrhh EnXAFA9wQMIS4sAaKByhNVAggw/IQAYviAEIYvhCFtjwhiwwgQ5NwAMWCKIhW2DDG/+I0JAnQGAX TaBGEyCAiyfs4gIQgMAFmoAAhiACiG14AxIcUgA9efEAegKjGBkSgCsyZAuhgMMWnZSDEkSjBCdI Sw4yIseUHKqNJYDjDfAIRziyUQVpOYAZF4KFUICiCAfoCCeYsIENMAEDF9kEJ6AgpjAtkhMt4IQm N6ECLnEgA5yIAxM04AJQboIDgmzIFT5xyANAMgQWUYGXqlVGVerCE4i8QQukcagSsNFJBMjIk4RJ kloypAar6AQR7+IkZs4EME+C5kyaKZEAKKIhNFiFLhAZnTnKMQcZkMYASrACJ53AUBmAY1qiI8cT tCAFGQEkdgQSCDYRhAa0YAUi4/D/JQ2IoBlMmEYoW9ACY2xgE1DQwEHFFAKChiAEKWiBCEAVgkZ2 qU31ZAgNzrAKRIogDhloQQY2wImJOsFTTCBoiGyyO42S4QxEFEAc05IRAvhypoeCkkRaupAYkAEN WzwAAQDzTKE+UwBFvckfGiKDMZABkSVIQQ54qYIVuJMT8TzBAD4CzngCsktxJCgcd7ABQIIzGqlk iAwiUQZEkrKRHGCCCCrKCYo2NKRn4kALXBAqVXHABaDKAEbKuoEdZEAlg1TIDCKRDEQ+kgPNKGhH 9qKVxCaEBY6ABCIn0844qiAHLfisCj6CE8sihAV5cMRmS3SXorJWpyQx7UFYsIc8/7jVnWUtQWjn GNEMTIOgISVodDYAXOKSUlQi5cCJZGsQFthhD4j85EM50MgQTOOvAw3VRVKQgRCooJGgckEJRtuC DaQlA8ttSA/sYAftFbS8XXpomAga1y7NNZRxUEFFT9AfKzaEB0iInECiswM63lQFN1CBbk8QzDm2 wJfwPIELdkDeiLpTBQRhrsB4YIQjbDYhPmmIlASGsf9WYglLMM9Iy6vXvTaSoCA1r0K/S92RYiRV D23BmFTloEM0BAeXqMTzNmAmNF3EAw/dwJkuEgLcnmADqQrTYVNwg5ScBDApIIiPOUUQHHhryHEB bwsq+hGMeIm4Is1xCDSASYdsefIhXv5C+bwZR2+aM5A5KURDrBGIQDyvtdZ4pqCTGoACdLHQhk60 ohedaAQAYs9+8MMckFWJXgjZ0r3AtKUtUQleOOAPf/g0qEdN6lIfohAPKMQf9GwiQ7g60n4YRqRl nYhh2HoYiUiEH67A6EQH4NfADnYYpwLBHwwBgkMYAjS6MARcNRtXzIZdwAhSAGhb+9rX9kIXYCAH 8woXkO9U1E8CAKNym3sZVyCButdNgogxpUQ+CfFPZJAiG5Cg3i/Mt75fmCnLwWDfL4SBwAdOcBjo wHJzQgHBFc6Dhjv84TwoAMJNOEIS6gABGM+4xiX+q4AEBAA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/searchall/journals/stemcells.gif R0lGODlhwgEQAMQAAG2KxRFAcKe52czW6LfF2lR2ulBzloqiuf7+/mOCoS1Xq9ff6wg5nBdGouTp 8MTQ4DtisYqh0H2XsXaRreDm7i1XgTxjipSpv5es1e3x9nGNqn2Xy52x2KCzxgAzmQAzZiH5BAAA AAAALAAAAADCARAAQAX/4OeJ5GiW6Kmm7Oq28CvH9GzX+K3n/O73wJ8wSBwai8ijUIIgMEQJAakg MAUIi4ZIsjCcBAsZAfB5bg4mw4MEyUCScGV8Lq/T7/Y8fq/vBy9SHgEKdBcEKQdafot8jYyPjpGQ k5KViwNPHh0bUIcjBQQjDQlkBQgFH6AqFRkDhCMMFwxjH1oRFyMKBgMiFageaJbClMTDxsXIx8o/ EAQDDr90CQ8DA60Tmcvaydzb3t3g33gWCAJPDRMFFw8GAAYFDxAShAQVX/YkGxQyDxHtHxw6mEiw IMAICB0UTAjHUFzDhw4jQlxEYI2HKFMENLDAwMIGCws+AKhw5oSpaCrG/wR4U1KEGhQbMkyUSHOm zZo4b+rMyXOnz55Af3oQGrQo0aNGk95UQABCAAAS9DDoIMBCg5UXKBhUyhWp165gi2FYkA1AggLv EkCwgLaAQXwmKijqlQEuCQW+3hlo8G4rhL1sJpD5Sjis4cKIY2howmBrAYFlDAQSQQEDGwRvTHQI +YJAAhMSIkx5YEKD6MSoD6tOTXixhk+QPRhYcIDDIAkCopK8MFjEhQxbVxAgEGFh6NEnNpxazZx1 8+fFMosknSq25CkLH5TUYPnEs7kHr3zecjoV9S/Q0ztfr/6OgzG1t254oCjBgAQbDGyQ0BiDQQsD 2OVBBWDkFsEA/hHQAR4AiVxwX34FLGDWBqbh1x57GF6oYYYcbuhhhyCSEAIAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://ndt.oxfordjournals.org/portal_imgs/search_result.gif R0lGODdhOwBQAPe/AEpSc1pic1Jig4tic4ODnHuczXNzg////4tie0pqpGKUxYus1dXm9oOcrEpi lFpilHNaUoNie4us3sXm9mp7g3taUlpqnLS91VJii+bu9mJic2pqe1pqlIOUrFJzpKS9zYtqYlpz nN7u9mJaakFaizlqtGJqc5SsvUFag1JqnJy0xaSsxTlqrGJze0FalHOczVpSYqS05mJqlN7m9pSs 3kpqrKzF1UpzrEFilM3V7s3V9kFqrHOUzWpqi0FqpJScrHOk1ZSUrJSctHtqg1pqpKS91UFinJSk vUpztHODi4uktKTF5nOc1Wpqg2KUzaTF7mqUzWKLxZRiamKLzTFqtO72/0FqtGJqe3Nqi1J7vVKD vaS95kpag7TN3nuDlHuDnIuUpKS0zYucrGpze6zF3mJilL3V7lqLxebu/5SktIOLnGp7i4OUpLTF 3qy0zVpzpKy91bTF1aS93qy9zaS0xZysvWpqlLTF5nN7i4uk1TlqvXN7g6y93oOk1aSszXuLnL3N 5pysxYOk3mqc1YuUrEFzrM3e7nN7lHNzi3uk1UpinEp7vWJqnIuctKzF5mpzg7TN5jlztGqLzaS9 7nODlFJ7xZy03r3N7lJzrJykvXuc1cXN7lJqpPb//5S03lqDxc3m/73F5tXm//b2/4OLpMWUe83e 9s3e/7S93lKDxcXe9r3e9sXe/8XV9s3u/4Os3sXV7tXe9sXN9sXV/72DakFztEFzvb3V9sXm/0F7 vTlzvYNqe//NtKy01WJiiwAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAI/gBtCRxI sKDBgwgTCtxRSyHBhrUiNnRIkaKACiMmKvwUJdWZT5/OZKlI8mAhCLxoccnlMMunLJUqZUm1qKRN gjBKgTDC0qHGmySRSIyIxAcAB0KH/hwY8WFTppGiGlT6dCCmBySykrCDwYUiOyi0kjBicFHMmgJh VqoZyValKE7OLIo00WzMu5UK1jKCo68Rvg5wGHHAVxGOQgUjQRo1qsqUEp+qMLZEpYCpUQcyo9ky 11YsxqAZQ2k70AqLHahTq069NBKszAdMRToDWw6VS7Bzz9BiC01u2KOBHnSdu4+W2lQgwWYM+5It Bp1+j4JSq6ct6zeJw0YDBbnyzHem/uT+tCgK5swSKuVKFQXkmfbtU4EMeeaMR/sGtcOGFf2A7e8H QKJHBrD1QcUiVcCWSAnX5bJILg4u8iCEEEr4oITYCaTfb/4lBxskJTAA2xYlIKhgW/LJ99IiIKn4 kRZafJLQhr/99yEVhsB2R4kJZpZIW4tkYeGFQ2ahhYUzvnZAJ+d5d2MssDnC44m2LAIjjFkImcqR JWmHhic1epgZiCLARsOUPgKpYiouqYhWRV4uIqKTmTmSRX8HjGZimlMtRZJ2VdjyQm42ZpbBDLDN YEstex7woy2M2CHpG4ww0oMdWNjhwRsy2CEDI29g6kFiSgZaghnIAcJhZjzQ1eij/jdwIusNNcQq KydIxLrpG5h44AESpGZWxVxn9LcFFZbgmZkIL7TFKJ59tHXGC1DwQC0T2EIxCBRQnKGLT1MkksgL AukChbje2vKJJhJ4IgETuXwrUC5MJAJEIqkIxF4U/PLrBBT98luRDGWk0AMjIfRggQUJdCqDDCk8 UIMvnCAcgh0WyGCBLxxYcINAVIXs50F27IJABEMMscsuUmDRg8ooD/EGFirvMoDKKae8CxHCUSQU U5gAK5DQDxHd89FIJ01QVEw37fTTUEct9dRO99GHIK8IcvUrr1h9tdZehy322GSHnfXVZXsNiymn nJKDDqbEHbcOObQNtw6ttAK3/txyn2JKDrAE3oopoIjid+CBn2J43KrMTbgpquS9iSqUw7LJ5ZgH TnnkebcCS96c5w1KK5e3ogooqKOuCuKXn34KK5SDbjrsrHxOOea4Ix667J1zPvomraQuvOeBY346 K3l/LnrkyreC/OeCdz67Kqwgn/csztOOS96npO6K6pZvYnn4p5tCvOnEN0/II4QQ4ocYjRyhBiFq iBEIHEKI8QUYhwjhBfxhEMMeViCGTGTiD3CoAxxAATnpse50poud8shXBzaAgRRhaB8p1EAKQpAC EYEgxQbZwAZSiIENgQhECTORBkKwQQxhQOEpOjdDWTzPcqeLXOySJ7judS90/qpoGyuA14rXzQJ7 p/jeDD0XvO+B4hSxo9wMYSFB8YECdlCcIOsuEcQizpB6rLhE9j43RNN9T4wO/B7oXte2NUKRia9j BeSYJ75WeOERlCAFJfBAig2oAAxewIP/1PAIL3yBfYH4gxrWgIdAfiEMf/iDF9QQCDz8YAUE8AIp ArFE9AkudksUHyz8EIhM1KEOBjwCH0p5v0ywIRMrSGEY4ECIFKogEyq4XwI3CQkVwAEVRwhEGACx u/BRcXeYyxvhWDELVsywmTM8xSyCGMciVq97qCui8FwRx07KTnxEhB0TMXeHUKACELAQ4x2S1wZY 8EF8l2inGNtwiVu0gXLV/oOEKoipClyoAhKtAATwImcK5O3wc28k3eXAgIcN4OERG1gfHib6hT+Y ABF4GMMY8NCCNDxio1fwghfCAAY2PPQRjcQDGwiJhy/o8I2sAIUqSoc83N3hAm3IKT0BAQlIAOIS YehpG4bZBkiYoaiA0Okl7gAIVLQBDjo1Q1Jzir4IBjFy4oNd+DYRhkzAEA5hSKEQMvGBMNAhEGkI 5gqEcEo4pCEQaiAD6FDnTO49EYy7Y5sOL/fGOhKCEl9QQRoa4YU/fIGAh+AjGCq6wT8c4QiGxUMm auc84XWvgZ3Tqus6ObnkXe5zqpOFNWEHvCcSjpvYTOjgTDHQtjVwhzm8/moXuyi5z5oOdaJFHS5O gbeYXjF4bXOFcGeIvMsSUYybMN8bu2e6L1KObQaFoxjq8AcRvlAMpIADGDj4QjXw8QgqYEMDxDBJ OHzBpGyoAwHC8AhStNcLhGiDTGEXW/NRL3KdPIUfbHCEIKTBsWlIAx/S4D8hoLUOwkwDCk9QSjhk 4rFisEEmyBBgIbD1CKhIrn1R5zfuFVd62dRB23zYticKz7InfuI1sQkKuMkUfcDDRereuDrmUdEM 8SSmGUzxOWLKFBYyDaIZpAoIM6iCi7AAaOSQx8V9Tq5tqyOeZVdHxfGBwrtXcChKH7HIOkyUEmt4 BBuOgIdGhPkRYcAD/iWOEABKOBaPj1jDH5TgQM+1ToqngIUsYPG8IgKCDGSAg6DH2gs+XMINgu4F GYpKzzsI2gyANoOgAwEIOHwgDlA1QwRnKMrWkW6KzmNiqFPrxfmy2MQjfmJqn6hNVIOurhFU3iY4 3VnQwYEPYVg0HMzQBVjAwaeShmocxFhpHAOiyGaAxB0ukdSjtuHYSQ0Dsy9BhjBoWnbk4xwr2JCE MTzi248IKfsekYQWwPkRQsBDB5Lw0CtMFA8UeMQRHlGHR2ggDYcIt0NNgIcrmOARRuZh6aZ4zFWo 4haqgOol4nmHIV/C4TVuw1GLINV6UvHhUG3FUS/wuaJewteDSx/i/qYIvBEr0bIjdqZvZ3zFOIKC m9wTYok5rDqtIg6HCg2DznsBVrBCAtcfUGAdLhAIOui8CDYQgxC6egI4zGGWGTRgESjtYDFMHdHN XR3uOgs8MUx0A2nAwx/wcIQv8DGSlMgEHlawR0pQwgtu/28j3Z5YPBjgEF4I4R4b6QU2mAHKCv0s Vu18inUWr3R35RwUqbl46vntdKwOBRE3d18p6lChiZMF8D6nxubFfIcmduIXnanqlzMw5lTsHn2h 2LrPyvoUAQ6wB8WgghOwwQ8uVIMQ4PAHNpzgBEcI6xFcKAYwZFANcBi+Gn5AiA6E4baMx+xMwfm5 yalACUIghBi2/u8FODSgCBnsACECuH0wgKHo0yVFExpBwPP/AQxi0L79qLc9a0bQdHWUNSyIyQdV TEAVRgZorAAJXNQFZjBjzMU9fKZNLCZEd+VMlnN/psM6eJM3uocHgbBHfyAG4RZIeJAEbAAIzpNn BDdQseNMbTQ4KwdBmwBrRZQ+5uM5oRAKOnZtZnALQ4ZjB5iABsU5+IVnOrQ5hJNnonNFS8ZEzrR5 uuNDrqM6lUVfQdZ43EN5MNZckHNMHPY84iNERMQ6VfaClDM6kIdNojaB6OODEiQ9vUNyrfNjAyVK VPRqNPQ6qsY4tNY7aohF4sQ6ooV50Gdn+Fc6L/VizSVTMjVz/r9jTT7YeNrGhtWXVYQ4PqwXhyEn fVDkQ6XXNhGoOlHUO1LEWuBURz4kcJMzOpsWUzrEZ0ukOmSodU82YsoEOnEjU1sHC4vnWeNDOAzE QIQzOHeli3EDRagzhDNkCngzjKvVOEPohrbDYcgUA1uwBUuwBU9AjdEYA9D4BNOojdFIjU9QjUvw jZPQjd/YjdFYjdpYjdgIjeH4BJOwjtc4I5EgL0rjEJ+QCvR4EEoRCYsABbkgEfWoj6mwBZ7wJgex JvfoCDPgCS7xEgGZGJ8gB5ZgkAbxLwpQLVGwBaYACVHALVHwkFUSJEHCA1AwJBQJMhARCZ+wAKlA F4sCkueiIQl50AfnkghWwwSSMDIP4ZIgSRC50CLvARJRcJI9CZIBAQA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/searchall/journals/ndt.gif R0lGODdhwgEQAMQAAMwAGP////G6wPjd4OaAjNg7TeFpd95YaO2krP77+/ro6vbP1O+vtumSnOiM l9EZL/PFy/3z9OR2g/zu8M0EHNUtQc4JINMjOOucpf33+NlAUtc3StpIWfK/xdc4S9YzRiwAAAAA wgEQAEAF/yAgjmRpnmiqrmzrvnAsz3Rt33iu73xfB4GOIjABAgYBBSIRcAAhB6CEADQsgAVgonMY QqsCYAXYaIgZgUghEhBQkOiAYRQOXAD1DVAgqUKMewAIAQNXCFGEDRZ7F0wTCA8kQAMidQMMfXJ/ AVkBGGacSBkdGp1lQB97qZ5OnHWrAogDVKxYGEAdcQVeiAavgT7BwsPExcYoQBmRdS+0BTDMOHVJ CM8PT8htLNcBECiDQEAEw8AuCAgSKBfnB6Acx/Dx8vP05NrEFg4ViBgAFxkBGPR4k8RCvROdxh1c yLChw4cQI0qcSLGixYvwwgU4wIyCgyEL3g0YgGBBhHS0CP8MiGBgHQJfBzwqSADBAx4jDxhkiMAg EoUGCRgsIHklwANQGiqRqTOBAgECBwAYUHBpJIA9rQ5wAOKgwQSaF55GNYBkwDuptCY4OCABAQYJ AqdWHbBhpIQFGRwA0HBFAYG6AxpQfReogEkEIzcgFkAgwoIKmRQYMBwB8QAPcRY8JfBAJk2bixs/ xki6tGkRgaYBMDPhVoCtGhOExVInoQhQQCJcYFYUyAKpGrU9KNKExLRwBCjs0RP86r0OvqUqiGNg T4UMOgMgkERIaQARzDUmpKVBgYCyncINUN7GAvFwBZgF2uM+eIHxWHCn2Q3o3un/AAYoVjEUaCCB ARxQIML/FOn0cMBTkUD0wFNJBWjhhRhmqOGGHHboYYfOwOCAAAIQY2CEJpCoFwsnOqRiMA8YENWH NNaoQzgCRdNCiC/oaMNxASRwgAVXKGRCOSkQGYCRJYCDnD0lvoAkCQkdkMEAKNqo5ZYuaEEIM05U FuQYwVVASzgKdMLEAa3k9gBv4STwW3UaxQLEAVf85t0dm5ApQAVMaOScAA8w8UkAGdAy4qBkIgDB HSNMohQTAwBqX3AJVDATBIekB4QCi7RBwRDiAYnANIhdqh4WbabxZnDbcSkrjXsgYsQQszwFmwAa VEGLB7VxJUIRX8hRB5mnBFABGmoUUWJ1jhjknQQYMJFAxKh8+NFfiWQy4YEFBEAnRyAGMMCEQJF2 d1MABmViwCb4caIBBkOkKQUtfjJ3qCvbsieAvqDcJ44zxPYin3+zJqxhIA8A9F0+IMXk2wITzOFM sEuK4BkEzzCTUwSV3fFTUENEGYZsxmkEwRyDShXBXC0DkMlYV0zQwKAaQJABdllKuu4IBrzMwEjx HsBAEQsI3AZVzxQ2wCOJHVyi01DTFW8BG3e8rcJcKzylD7YGsEAk7jjIBJMN2db12my37fbbcMf9 QggAOw== ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://annonc.oxfordjournals.org/portal_imgs/search_result.gif R0lGODdhOwBQAPeoAABialpqnPb21c2DlOa0pNXetLS0tP///3Oki+asrLRScwhqas17i+7VtO7N tO7mvUGUe96knGq0rN6snPbmvbTNrHuDpLRSe71Se8V7i+bmvdXVvebevVJilP/2zcVzg83Nvfbu xebmtMXFtJTFnGqslNWknHO0lN7VvWqki3OslJS9nEqUg5S9pDGLe2KspMXVrGqsi2Kki+bexXOs nFqki///9nuLpMXNtP/m1easxc3mtFKcg6TFpHOklFqkpEqcg3ODpL3FtGqklPb/xd7evd7mvXO0 tGKkpIO0lCmDe1qci4O0nBBzaoO9nMXerL3VrEqclOaknEqcnKTNpNXeve7uvazNpEGUg+7mxWqs rMXVtNXmtJTFpJzFpKTFrEGUlFKci1KcnLTVrP//1azNrO7uxYu0nL3VtN7uvRh7c+buvWKsrNXm vc3etDGLgzGDe3u0lM3mvTmUixB7c+7F1QBzajGLi/b2xUGclFqspJzNrAh7cymLg//2xZy9pDGU i8XetDmUlCCDeyCDgymDgyB7cxiDe+72xRiDc1KUg+bmxQhzar3etIu9nP/uxQhzcxh7eymLi/bN rDmclHuslBBzc+b2vSCLgwBzc1KknBiDg/bevRB7e6TNrNWDlP//zf//xfb27gBqYgBqasVqi8Vi ezmLewAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACwAAAAAOwBQAAAI/gDJgBpI sKDBgwNlkFrIsKHDhxAfCkRIkSIVQxEzanRYcaAVM3ishDQTCuEaHhtJZYKUqWXLhXZiQoLEseOa NYjWmLGyxk9FJhsj3ekziM6hQ5ki9Xkz6A4hhxM7SjVYpknKqwyjTt0KKpAarFe1cp3aBiNYjWPT guLy9WxEtWkDWXUrEe7YK3Tr2uUaB0DerHvHQvi7MPBYLnPzGh4L9K/YxRTxKHEMeSsVyhT94KEY asxBPGM2HwzlQnFFN45A4SG5WrUfR0REIwLVo01FL6YpQjmBx5GXMi28oKlAhUqPLaDQBOrBxEhF RG3PPvb4xEsjL3L2eHHzu4sXKE5A/jFB5KiLaIol6E4H5eZmjzI7yoxx0+NLGU8woIBqg4ZLGSsd QUEXRWnscJ5UblSwFXRujdZFIG6oEMhWUAzBFRANGuSFFwMZwQIeIDrX4Ww3rVUJKH4YIRpOOYG4 Bih9SWfQEjsQxAIMNVAhAxWglEFFGfKtUIYRlfQWiAqXdAFFDWUMAUUgqeElY0EsuEFQGFzEcIkb TFAxBhmILAGKFYpw2cMKZDjiSA2gqGAEFI6gAWAgbonFBBMD4VFDKAhY4cYZvpGxBguqLcFlC46Q 4cUKVHynGg9lDNQGI2d9NsQYaXgRCBE8tDGGD21g4UggXY5BxRYypCGDHI6sEUcJ/kxwAcoJVoKS RmJhIeSGG7Ph0UZOtq3RSEk7BGsbIryC8scOY6QAimcDpUEpWOsZhgcPOwQSyBiRDsSFHWfR4FNl BbXRg6wFzDbQFm5BogK5W3nhF1idkEICvFIpdNYhC/HYkWYo+jGuQZMQ0BEeg7jFLykL+EvRAyD4 oUEWISAUQQbVCqhwQxwiZAYoKIywAQdFmFGEBwVJwUC1KG3cUBwIzbDIBkHcYEEHFgQAwkACiJLA BxqIoMFB7NK1cEMspHHQDDMYMIIQI1SBg2g2HKCDAiZMYEIEjxBEBBx5JQKRIVccFEIRRYRQcUE5 1FHKAKZgcMEnDhA0xF9HP7SE/tIE+eFBFgEX5IcDnPjRAAUUNIAyKEkQlvdDlsTx4l5EpEeY2Bup EYdtagVyCmELPZ4RIzxQMXlHRDQSBugMib6RJVjEUUZ7iNS+hhtUlDAZ662DDokawNPE+0OuD298 8cbzjnzyoC/PPN7PP+989C5HxBJMpDASE0MzCW9H98I7BO72MIGbEfKWsKGHBD/8EIX6bPwACR2C TAHIIXkI0kceU9wByB2CAEMU5jCFPBCifmAoYB/A8JSILG9+g5gJH+ZHBzqQAhKEIEQnBpHBowxi E4SggyUgEYnurQR8MzEfRKaXETrkYQ6FAGAe+iAJMNxhDip0HOtGQQoeMoSH/j5kHQsjEglBzGEO gCAEGAQhCP/d4Q0MfCETMeGUOdwBDG/YCObyAolBFCKDkTgEUTjYBzpEwihhPAQFDxGJEG5kiBCh wxwEkT8w9EEQhIhCHiwxPDhmJIfSIwwfrkgITBBCEjREJCEOccihRCKJhejDUPpQiDcSBoN9OIQX I0kIokQiEk3p5CHuoJRCvKEPnQSkQ5bHR1UyxJXMQx4dJICEF9gyYQ2JhCaiAAYx5OGXktBf/gQB CEDkQRJz4N8SYblKjTDCEpaoYPhg0j01plB7kHjm/CBhBxHOZFop8SP1LDnOPpbTnOcUYjrVuU4d XpIl4MsEHfhAh+7RYSXMmzzfJY8IQEDMAZFLzAMY/HnMKETCaJe8wx0KYcU+9GEOlCJf+TISCTBY sJl/gcQT+wAISXSSEp90yxSOIAjiXdKhDiUEBwkRw7OMYg5akIRJM9rBQ3RCpRwUo00z0kWVFiIS c2DkJyORCVKIsyGQEEQMPSpJjkpCoRm0ngztR0dl3oEmR2WIPCk4wQp6tYJ8cOY8KbjN3rXzLwEB ADs= ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/searchall/journals/annonc.gif R0lGODlhwgEQALMAAHetrUSPj7vW1pnCwiJ6ehFwcDOFhe719Wajo6rMzMzg4N3r64i4uFWZmf// /wBmZiH5BAAAAAAALAAAAADCARAAQAT/8MlJq7046827/2AojmRpnmiqrmx7GgcAOE4jBY7w4Poz Az4H8EEIPBoLxy0nYdAGCITFwAwCeReBkKK9MrGPg7JpCI9xCQlNknAYH46D5PfQEojxAtTF7/v/ gIGCgxtJDgUtYCVYaRQFBwsTBFUqa4SXmJmam5yaBAMDZURaAwUzCgSnBHoOA5+tiEkNAmJlqnUH qwoDFzgIMEOnohUFuwUEuxOqtwQHCgUBPY+lCj1UDqICzwMHiASGNFtzcp3l5ufo6SsGAjYtMlIn AQmgFwQMDAMAiCsIMuoAAwocSNADAwBOeC1x4M8BgzlxDLRxh8PIgkg7qgBYgKjahRkG/wosUKiI wgBxErRIwcFwxsMHMNLMMEIFSIJnasaIlHlA1CReC8iJufNgAdGCSJMqXcrBqIQGDjBiAUOHToGo Kc9UaZeqVoVJPWaspEQBao+ciKZWSTLhV1GtCi2dfIMVSQB4FFg2Ysq3r9+/gDHVnJAACDYBbwIr Xsy4sePHkCNL7uNk74qSIx4JoDLlQLwBOFdYmky6tOkQBhTIUgYAwQABpYjASyBgyIMCDOgxIKrI dW53FhrQs31yAYDEEhA4sDzUR+vXsSXcYyBgtwSJ+fjBGXN7QO5hOxLkO+7vnwzbp9OrT2qUCrmM CjKGdWjlRvw6WnvQugPgLAVnEpxUBuxmWaHXBXzysYHNbW480AYiyg1hyQw2TNIIHVoYMQMvs6zn 4YcBHdREK0voQNUWdByhgAIAKJCfBKw8YcGJXvg3gRMG1pAgGKNNYAmPY2SYU3I5PLJXGwB0A+KS TG6S2n8LqjUfEHRgcdWLdbwEFXgSXKTgHQRKoMB7VLwkZYA6OnjHSfwxNOQDyklBBS8uyRAAeKs1 qeeefxRxp3QBBApNoH4GsEqghiKKiCnHGfAnoncU0IAMwFmQynETIMplWTKABymkMJanHaPxwBTo MKJKdwADiHoUiWt8xirrrOo0sEt/QyRQGK289qpBBAA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://ajp.amjpathol.org/portal_imgs/search_result.gif R0lGODdhOwBQAPcAAAAAADFKGEpiIClqIIOUWkqLMUqUMf///2pKGHNqKYt7MUpKEBAYCEp7MUFz KUp7QVJiIGJBEFJaIClKGDEYCAgAAFJzKUFiIL29rDlKGEF7KWIxEGJaGFpBGIN7OSBKGDEYAEop ABAYABAYEHtaKTFaIGJiILSslGJiKUpKMVJKMTlBECA5EDEgADlqKXNaIDliIGJqMRgYEEqDMZSs e0FBGEpBGFIxEFJqKUogCFqUOSkgAGJKGIN7YlIxCFpBEDlqIEp7KVoxCFJqIEqLOfb29kFSICkx EEFqKZSUc0opEHNKGLS9lFp7MTFiIEpqKUpBEGpBEGI5EDlaIDFSGHtqQTEYEGJqINXezUpaIKSc e1pKGDFqKVI5EClaIFJBGDlaGPb27ilKIEE5EDE5GHNBGDlzKVJKGCliKVJBEEFSGBggCPb2/0pi KTkgCDFKIGKLOSAgCBgxCBggEM3VvVpaIDmDMUpSGPbu7jk5GAAACCkgEDliKVKLMWJBGDFBGHNi MTFSIFpqKUF7MZSDOUo5EHNqSjlaKUo5CCkYCEFKGL2snCAgEO7u5jEpEGJiQTlqMSkpEGKDQVo5 EDE5EFpBIFIxGDmLMTEpCIucWkoxEEoxCDF7MWpSICBBEEEpCDEgCFJBIDkpCEExEEpBKTExEEEg CEFBMWJaMUpzKaS0izFiKSkYECApEDFaKSk5ECApCDkxEHN7QTlKIBgYCEFqMRgYACkIAN7u1YNa ICAgGCAYCCAYAFKDMUEpEIuDczkgEGJSIEE5GFJiKVI5GClSGClzKUo5GCAQCCkxGDEgEBgYGCkg CFJaKVJ7MRAQCBAQAFpKKcXFtGJqSkExGEoxGDlBGBAQEHOUSkFiKf//9jkpEO7/7hgQCCAYEBgQ ACkgGFJSIDk5KUFaIFJzMTEpGBgQEBgIAGo5EEqcOf/29jExGBAIAEpSICkpIAgIAAAIAAgICEFz MQgACBAICEFSKaSclDkYCDlSGBgpEINqORAgCAgQAHtKGFIpCObm3iwAAAAAOwBQAAAI/gAPCBxI sKDBgwgTKlzIsKHDhwOLFInIjY1FiWzUsSmiTmARPB83SpwIMSEdJkykndBi78Sil4swSMPAxKVK lCdy5mSi6kRPe0xO6tzJs6WqljntKUV6wl4QA5f+gLDxBEwIf0vQ8bBwQQMUIUDylHAQCxOiT4Vi FSqFb5ucYmuKYaLA69sOKvhe8fvz55stEYDZ2YL2DFYcaH6+QAGFiRw2SQl4aCHwKwmBTIBeEICD j5ykaY8MoXpUJRqBJmgi3QrwR5myVo5WZfhEqdSrSHFo7YkUiRGDNXnyxOo0rN0NN7VK4JiGQwUq E4ZeSEdlKFmsYMN0yAqlwhCgLYDq/ogC5ebIhFF/0PzBtyqPqRt52k35Q6sbbwa0GDlaVyebGCMb 0PCLJHY0YUg0hvTQQxU9qPCIOCok0cMDSTziRB9JJBEMMRL2gEoTOLDAwhtusGBGLKMo8oUURiTz TDe70CIDA3Gs4wcSR3gRzQETxXQAHRgc8E+QSaiDxQFH0nGANHJIc0AYjfzTiEAY0DENLyWU4oYb xSiSARpmhNPBH3scwQgtr7AQhzI4DJLMBHAcYA8djWBRhDTCHKChnEVM+UsjU54ASyN0LCLQCXRI 8w8d5UTChy95MOOJETC8UkqYfxzBRzG0BBKIHAxkM4UyyJyyZCPcLIoFKQf0EMwB/lNOmUSdB5ww QCO4KKnOCaigEsYJvDhixh+reLFHIFOM8skfLszyhzViMPAHayzg4IcpyAijDR4n/BIGFo2E02oK fP5zgBZFKLkIGLmecIA6/xSBDS5JtPCJNUYw44omn2xTwyigrFKDDZq8MUEeAagRywzj+OGGOLUC 4GuQ04x7wC94yPqtNieAsKi7B2CABwH0FtKBEr5sw0VwgaCxSiTIKvFDIXmkXAgLBmTgxySoHLBI BXOS+4s2PZCbRBFYaHOkk//YE6+UUh6QCTdJUMFFFppQYM0qh5AB8zaxcFLDGFO4MIpt+byyiy9d dNJDNImooIIMDz7ozjTioALh/i+GCCNLEoaQ0oOEgEjYhiTDfAAKFzxUQ8EnmpRSTB6adCAGFwEE EEgNAXhyxDaJUDBKNZV0EgwppIATizjriBOOMCnEsk4okcQSTSjBqBDNF8HYIDcq08ABSStnuCDM EzVoMokRU0ihiSbKvBLINoFMYA0nJdwADCjb7CKDN96Ao8szMpjjjfnLgFOON7pcY44M38cCzh7K 7FEOI4xUA0gNbqBgRiB/cIAmQtAOM1ijBC4gAwXc4ItYFEMMyUBDEwrRr24A4IIVmAc9NqjBblSg G914BwDiEY93wAMeFdBDPJ6xi20wgxm7AEU3EtGFSJTiD3xIQwcmIYFxZKAG/sUohCaAIYpPiMIN u3BGEACGDBI6MR706AY9nkEPKG7wiU98BjuU4Yg97MER8QDAPJ6RiECUwBpIwAEHENAFIRxQE5QQ wx98cQNNbCMYBdhDWt6BxSheEYpUrKITBblBEEJxF8wA4Si+cAQz8OENq4BAFJRQAy9swxFc4AIn /rALYeQBCQKggCZiMcInFpIWVaRHfaQoSCtG8RmA7IY3dpEIkyUiEb4IRDuioAkhTMELjkDDBO7x hxJ8IhR/cIQS+pUIeAxyg7tghTdS+YwXSfGZVlwhCGdYCFAkAhTAyEIGzuCAQWRhFKvgQluUUYw5 ovMZFFBGHfsYxV2AsJCF/pQiMgJpym3uQhluYAUwLMEBMxgwEoPQhBuU4YtRbMMMpRjFKAIAClPE UxmDJGE16WFPKrJSlRt8USsBGUVkIGOGo2BoQykQiAz4o6Ga8AUw+MCFEjTjC6OQghtAMQpkRJGV 3aBFPLqxh11MMZW08KhRsQjFGSIjRrvYRTwSQclVmMIUUxhEO+pHvVUMwgKO6AAFtuGHRORzm4U0 6hSrWZ9n1GekJPzpT0H4T2YUYhBHEIMTrDGFTWxjFDdgBr4IJsptELIbIg3kBqcIwlL0JqmL7SM/ h0oPZdjAFzZwwSouFQsoXPYLUxiHIojhME0kopR+xCcUrUjULkrxo4SM/ms1SfjaQjDCpMgo5h+8 gIRjnGEQaqhBF5SRCGBY0Ikv8igsWbiLVnyABR+FpRUnS1InRnUXkVCGEtDphTm4ogNRyEIBppCL G/jiE9J95k/jsQdffCEDvYhBJFQY2ZBSUb1OhJEjlAGMhoawBMJYQCpwgIAbCEMJzNAEU0n6jDiM 4R4deIUHOqGPXVRgsafE8B8H+VoUmawbJRgEF/7AiTpM4hi33IZk09qNBWwjqDzQRC5eAAB8MjaV R4UrCQHADEcAdkvKIIMZ1NABidJxG3xc4WxJGNUoxnUXLyBEP066TbRWcaM6jgc8ErGHRFwSGfcY hxmQcAU/DNEXiYgr/mLvu1pXVhEZvqCyNa1pSD8umIQV2MUeSmHPiuJjHDoIBiN8UYhIrBXLrdRw N+KRQbnes6nUvTMymBGHaiJjHBpAwgwWsIcuaEIUP7XnUePKWCp6sdLPmEMrIEvIDW/YifP45h5g BAoHlMAGWyjEMb7gX1pMc61ABSEVrflWRhyhA5pIZGyxiUU97MIRiN0FMe0QjCWYmRmJINUKNbxR xWIYsVHM6ShYcc3VLhuLLDRkNwbhAgvoYwm+QKQM6TGPuDY1lbBdc1S9wYhZ35Pbr+5jLOKQCCNk Yxyy0AdiNWFUQ8YDsuCWK7CpiAxadHTY9j10ZJlKC0d8YgwOGEYV/vSBiUh0YRd/2AbDW9jTbb7o pDdW9FGriWgN//Goz/5COAzwBEDkwg+OAF0ebpCDBdiAAsO1Z3TTunGb19zeG9RNfVpI6GCkQgfY AMQXgFFcZCTCEYXoQiFItQtvL1akTZe5zQVJS8TyuBA2qEMf6oCCF4wh2XsIYzyeTWVR5zPtI8Vw zRW96EXTMBiogEMCctGPWGhChlgc4d+Heo614jjRa8cwa7fpjWecYxQSkIQgILDGXWhiFFlOKyzP vgufvjrzcKVHj8fwBbAhAQlP6IUFJJAADgS93PHgBz9Inc21uxn20j30rJGB0xqk4wkWkAQgUEAI WfCAERW47zvk/iCHO9vc3LDPZyJYkRZajsIFdpgCMHQvCw/kQh8egMMWRoFFORyBAXdmqqtdudpu OCIWKEIMKFYDl6AiBcAHM9AEL0ACuZALCaADe2Bag8QA+TB8+XeB9UVbkcAMG8VArzAIbiAEk/AE 6cBzKCALVSALOuAIvtAN9XaBMGhKmqdNTqQHvjAMgZAN1JYDEGAG6TAIEkAODaADOhALXYAMepBl MbhgZ8cIRlVv8wAA52ADBeACbTAOqUAMM4APBXAB49AABZAJKGADL6AJS7aEMchRLPgDwgBL3RAI QGgHRnABLnAHv3UMdjAISDAOhUAC6JAKP6cMi4aGWAQjVTQP/nUWB6DQBVvgCG6QCzpgBDOABKkg BSjQD3VgAMExAG8QC1KwBFHgAoUwClZwDi9IiCUEClagDEm1DXl3SG6gCcvkBwvQAGqQCsPAAX3Q DkhgB45AVTdwA8GwBR1QMzewX8fFVNWkQui2C6MgRF1ADInADHwEDMpAD5qgBjiwDXmgAS+wBCQg CA5gBpdABYIIDFKwBV4QCDCABDVwD88YT1IFD2uGDPTTRFA0jWQkCtOYBpOwDUYQBHJwDr6gUGRA BKkgAVnQC1LQCQggCBLQAHwACspAAb4wCTwQCKUQC0gQCPfQBRLVAS04VcpAdQ7FDs+2Dd1zDsXl CxBgAZrQ/guKMAi7oARdoATWMAhjMAOaIAAK2AkcoAMWsAVjUEua4AOmEAgusAvpoJT4oASTZEfO OAZINAZp8AVlMQrQAwr0MArHYAMzIA8C4AyKYAZ5MA4GwAfb0ABbYAF9MAOyQAiEQAJbkA4WUHuT 0AVTYAxe0ArPEAw4MA5cMAYR4AY34Acd0EZR0E2d0AFbEFWOAAr/2AcGUAoasAAWcAUWgARZMAM2 0ABikApbgAAcAAEq6AztsJCyUAaj0AVGYAaM4A1z8AwIwAMGMAWlMAaX9FejkDIp9QXQg0qOQAGJ 8AdmMAUXkA1P0ACC0ARtgATOgA6d0ARIoAlL0Am7ZwRP/qAGC2ACuYAOEYBOVMAIyWANpRAMPGAC JlADR2AE4eBphNZTe7ANXeALjtBxSJABrYAEhQAHfQAIstALCQAITSAIvdAASyAFEIACX9ALUKAJ hfAF/dAPZSAFUYAeq/AKtNBj+jAJNzAJX3AGsyAP1hAAn1N2yjAKMTYKSpABvbgKDdAPCTBh/WAC sqAA/WABW6MIAkAEl6AGffAFkyAE6HADZ5AKC3AD+DABLmANkSAjZyAEn3CYyHYGd7CQzEALtKAM nZAWPxALpeACXYADwYAAC0gC5OAABUAOqIANAlACZjADRzALBtAAUjAJNbAFQqAIOIAEC2AG+DAF NRAL/nNAC2QgAAWwAFLgAfpAoRsgAJGwCkfgCMMwBSuQBXi1CsOQC52wBS8QDIIgCJFgB+PQB21g AHzleEpwBlHgC2XjAkqQB1NgBEbABzXQARkwC6/QCgWABBPgADGAA+5XBlEgAUhQDAGwCqtQAIHK B14AA0PgB2eQBcOAChKQDhlAjhdQA6kwDkc0CuEgAONQAtlgDU6QBy4QCPjgAg5gBIVQCCjwCmtg A/cwAQ2QCjBQBzzQgOiADtsgBrPAkX9QDHcAAThwB9iAA+3wBcLRAL1QA+uwDeGwIVJwAx0wCOsh AEbQCnDqAIrQnoVwBoeQDYGgan4gBHnQAPiQBZIA/geMSqH+2lAB4AKpwANScAw4IAsFAD0uQAQ6 QA4EowSY2Q7hkA01sABt4KSl4AhkwAXkIAGvMAWCMAwZ4AuvsA7W0Aa+UJDbEANNIAE04AFlQKQp s7XEIICpUACXkAV2cA95oAMcEAPksAA80AEQMAivGQh2kAFTkA2MEAlkoAzWgA/t4A+aYARtkAcj IAMOZQYaMApjsAAr0gUWEANR4AdEFzpjdQNkgAQOkA4X4AC3gA9PwAPBkAWx0AAzcAEwwAWRcAR/ cAl2MAatoAizsKGMsA1SsAFgWgpHIAOOUApvMQgl8AcKQGFJ8DeEkAuAILnVBggJkAkKgA2ygA31 /qADMZCC2EAEFtAEOrCL4UC0EoACw9AMvcdpkTACsTAJo2BDY6AWkSAG+5APaxAJKKAAhEADmUAD qkAI+5sJhPACMUAANCCXWqAFhOAB+ZsJSZAJmVC92EAABNAMMZAAMSAL7Vd9kbAbvdEKkeDBjNAK a/AGa0ALcsAIceCVNtAOY2AGwuAAZDAIpqAMGnCvQ+AMddAPFyAMNeCFhZAFDrAG9es1XdR5z8AI 3bANjCADrLANc8AbrdAKvoEf+TAHazAOf7C0yuAvqeCuj6sBbmsHG/ADZuAESBCRDsCOGTCHLLDE 9zkHeaBnMuBWrfAFpSADu9EKMhAJeRCb9VEm/mMQB0ZABrWxDfdgDYqgBjNwB9swA8hQAjAQAjcA A38ABEgwBbmnCP/6B9XEAPgTB4iVH/wWCWPQBTYgxYwwB6osA3IgDLGwC7HQXmOAQyNbDaEgCNSL AP5AIHZADLzzCEQgCToABzFQCdSQDLSwBrOJHzJQH1oqA/jzf/jzzHPAwa0gUd3gWI7gCHkwDbKQ CT0ACAiQBDSgAJNgGQqCDdgQfzTQA7/QA9OQB+vwDAwQC0mVavgDP3s2n3NwJowlA4VqTzFCC1Jc O4tbDCXgCFPgqnbwBErQCZcAAytQAkawAOEwA086m/zwWMKBWP5iA44QCaf3t/fhVrlhbyTEhw9m 0s+M8AxG4ABcAAMw4AKD0AB5YANmANPt4QR84AJ7UMJzcAQRtQU4FQkMMAfHgABjkMpzQAZksLTb YCYMAFfPwAx/QAZ7oB+08Ab40AoTYAZcIAAWEADtoJ0FoAiT4FUskMy0oGpHEAnB4MqlwAgRpc3X rAhnsLQf/Az1VkXQ3A3KcAwBAQA7 ------=_NextPart_000_002E_01C8560F.EAEC9310 Content-Type: image/gif Content-Transfer-Encoding: base64 Content-Location: http://stemcells.alphamedpress.org/icons/shared/searchall/journals/amjpathol.gif R0lGODdhwgEQAMQAAP/MAP+ZAP///6htAfTSftG3fO3fveK1ALaSAejSofjx4OKIAO6PAMZ3APiV AO6/AM6lAfnHALGH