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    The equations in this article are MathML-enabled. = Install MathPlayer = for=20 free to take advantage of this.

    Software

    GliomaPredict: a clinically useful tool for assigning glioma = patients=20 to specific molecular subtypes

    Aiguo Li ,=20 Serdar Bozdag ,=20 Yuri Kotliarov and = Howard A Fine

    Neuro-Oncology Branch, National Cancer Institute, National = Institutes=20 of Neurological Disorder and Stroke, National Institutes of = Health,=20 Bethesda, MD 20892, USA

    =20 author email=20 corresponding author email

    BMC Medical Informatics and Decision Making 2010,=20 10:38doi:10.1186/1472-6947-10-38

    The electronic version of this article is the complete one and = can be=20 found online at: http://www.biomedce= ntral.com/1472-6947/10/38

    Received: 23 April 2010
    Accepted: 15 July 2010
    Published: 15 July 2010

    =C2=A9 2010 Li et al; licensee BioMed Central Ltd.
    This is = an Open Access=20 article distributed under the terms of the Creative Commons = Attribution=20 License (http://creativecommon= s.org/licenses/by/2.0),=20 which permits unrestricted use, distribution, and reproduction in = any=20 medium, provided the original work is properly cited.

    Abstract

    Background

    Advances in generating genome-wide gene expression data have=20 accelerated the development of molecular-based tumor = classification=20 systems. Tools that allow the translation of such molecular = classification=20 schemas from research into clinical applications are still missing = in the=20 emerging era of personalized medicine.

    Results

    We developed GliomaPredict as a computational tool that allows = the fast=20 and reliable classification of glioma patients into one of six = previously=20 published stratified subtypes based on sets of extensively = validated=20 classifiers derived from hundreds of glioma transcriptomic = profiles. Our=20 tool utilizes a principle component analysis (PCA)-based approach = to=20 generate a visual representation of the analyses, quantifies the=20 confidence of the underlying subtype assessment and presents = results as a=20 printable PDF file. GliomaPredict tool is implemented as a plugin=20 application for the widely-used GenePattern framework.

    Conclusions

    GliomaPredict provides a user-friendly, clinically applicable = novel=20 platform for instantly assigning gene expression-based subtype in = patients=20 with gliomas thereby aiding in clinical trial design and = therapeutic=20 decision-making. Implemented as a user-friendly diagnostic tool, = we expect=20 that in time GliomaPredict, and tools like it, will become = routinely used=20 in translational/clinical research and in the clinical care of = patients=20 with gliomas.

    Background

    Gliomas are a family of malignant primary brain tumors found in = adults=20 and children and are associated with a high motility. Gliomas have = historically been pathologically categorized based on their = presumed=20 histological origin (i.e. astrocytic, oligodendroglial), as = determined by=20 standard light microscopy-based cellular morphology [1]. = These broad=20 categories are further subdivided into the "grade" of the tumor, a = representation of the predicted relative aggressiveness of the = tumor as=20 determined by other histology-based variables (i.e. necrosis, = endothelial=20 proliferation, nuclear pleomorphism) [2]. = While the=20 histopathological approach is still the standard utilized in the = clinic,=20 it is well recognized that such classifications are limited by = significant=20 intraobserver variability, the lack of a biological basis for the=20 designation, and the relatively poor prognostic or therapeutic = predictive=20 utility of the system [3,4]. A = more=20 objective, reproducible and biologically meaningful classification = system=20 is clearly needed.

    The molecular stratification of glioma patients into subtypes = is the=20 most direct way to translate genome-wide high-throughput data into = information that can be used in a clinical setting. In the past, = several=20 groups have attempted to identify brain tumor subtypes = computationally and=20 stratify glioma patients into subtypes in terms of the gene = expression=20 pattern of their classifiers. Limited sample size (11-84 samples) = and the=20 subjective selection of gene features, however, impaired the = robustness=20 and clinical application of these classification methods [5-8]. = Recently,=20 we established a robust and reliable glioma classification system = that=20 includes six hierarchically-nested subtypes and six sets of = classifiers.=20 Derived from transcriptomic profiles of 159 glioma patients [9], = samples are=20 separated into two main types: oligodendrogliomas enriched (O) and = glioblastomas enriched (G). While the O group was further divided = into OA=20 and OB subtypes, the G group was split into four subtypes, showing = hierarchically-nested relationship designated as GA1, GA2, GB1 and = GB2.=20 Several recent studies, using other large and different databases, = have=20 likewise confirmed the existence of four subgroups within the = glioblastoma=20 designation. Whether the four subgroups identified by these = different=20 studies are all the same is not formally known at this time, = however, we=20 have found significant overlap between our four = glioblastoma-enriched=20 subtypes and the four subtypes identified in two of the largest=20 classification studies of high-grade gliomas published to date = (data not=20 shown) [10,11]. = To=20 translate our glioma classification system into a clinically = useful=20 application that is readily usable by clinicians and other = statistically=20 and computationally na=C3=AFve users, we implemented = GliomaPredict, a=20 computational tool that allows anyone to reliably predict the = subtype of a=20 new glioma patient utilizing his/her tumor gene expression = profile. As an=20 output, results are summarized in a printable PDF-file.

    Implementation

    Design objectives and specifications

    We aimed to develop and implement a tool (GliomaPredict) that = could=20 easily be used by physicians and clinicians, as well as laboratory = researchers, allowing the fast assignment of new patients to our=20 previously-derived six glioma subtypes with minimal technical = difficulties=20 and user interventions. To ensure simplicity and eliminate user=20 intervention, all the data transfer steps in GliomaPredict are = handled by=20 perl scripts. The navigation interfaces are simple and intuitive = and the=20 output is presented both quantitatively and graphically to enhance = the=20 visibility. Most importantly, we took the user-centered approach,=20 designing the GliomaPredict as a plugin application of = GenePattern, a=20 powerful genomic analysis framewok that provides easy access to = multiple=20 applications for gene expression and SNP data analysis through a = web-based=20 interface [12]. = Data=20 formats and the abundance of other applications in GenePattern = potentially=20 allow a further integrative analysis of patient data in the = future,=20 combining data as disparate as genomic alterations, ChIP-ChIP and=20 protein-protein interactions.

    Algorithm for assigning new patients to a subtype

    GliomaPredict facilitates a supervised PCA using predefined = gene=20 classifiers to assign new patients to the six glioma subtypes [13]. = The=20 original algorithm was implemented in MATLAB (utilizing PRINCOMP = function=20 in Statistics Toolbox) that can be mathematically described as A = =3D=20 U=E2=88=91Vt, where A is a = data matrix,=20 U is the basis eigenvector and Vt = is=20 the transposed matrix of all eigenvectors. The PCA sequentially = selects=20 new orthogonal coordinates (columns of U) capturing as = much of=20 the remaining variation in the data as possible to effectively = reduce the=20 dimensions of the data.

    Algorithm for assessing prediction reliability

    We computed the probability that an unknown sample belongs to a = certain=20 glioma subtype using a supervised PCA of gene classifiers; the PCA = projects the unknown sample to a n-dimensional space of = reference=20 dataset. The proportion of variation of PCA components is used as = a weight=20 vector to adjust distances. The weighted Euclidian distance = between two=20 points U =3D (u1,=20 u2,..., = un) and=20 V =3D (v1,=20 v2,..., = vn) in a=20 n-dimensional space is defined as ,=20 where w is the weight vector we obtained from PCA = analysis. Based=20 on the weighted Euclidian distance of unknown sample to the = centroid of=20 the training samples in the reference set that belong to a certain = subtype=20 we calculated the probability that an unknown sample U = belongs to=20 a given subtype Ci as ,=20 where m is the number of clusters, and =20 is the centroid of samples in subtype = Ci.

    Computing the relative distance of unknown samples to other = subtypes,=20 we defined the relative distance as a measure of a sample being an = outlier. In particular, the relative distance rD = of an unknown sample U to a subtype=20 Ci is computed as ,=20 where =CF=83 is the standard deviation = of distances=20 between the samples of a subtype Ci = to the=20 corresponding centroid .

    Installation

    MATLAB version 7a or higher with Statistical Toolbox, Perl = version 5.8=20 or higher and GenePattern server version 3.0 or higher http://genepattern.org/ webcite must be installed on the server side. Acrobat = viewer=20 should be installed on the client terminal for viewing the = PDF-file,=20 summarizing the output. GliomaPredict was tested using Internet = Explorer=20 (ver. 6.0 or higher) or Firefox (ver. 3.0 for Mac & PC or = higher) and=20 Safari (ver. 3.2 or higher) (Additional file 1,=20 Additional file 2 and = Additional file 3).

    Additional=20 file 1. GliomaPredict Document. The = document in=20 .pdf format described all the features in GliomaPredict and user=20 information.

    Format: PDF Size: 156KB Download=20 file

    This file can be viewed with: Adobe = Acrobat=20 Reader<= /SPAN>

    Additional=20 file 2. GliomaPredict Installation. The = document=20 in .pdf format provides the GliomaPredict installation = instruction.

    Format: PDF Size: 138KB Download=20 file

    This file can be viewed with: Adobe = Acrobat=20 Reader<= /SPAN>

    Additional=20 file 3. = GenePattern_Matlab_Windows_issue. The=20 document in .pdf format summarized the potential issues involved = in using=20 GenePattern and MATLAB associated with GliomaPredict tool and = resolving=20 solutions.

    Format: PDF Size: 59KB Download=20 file

    This file can be viewed with: Adobe = Acrobat=20 Reader<= /SPAN>

    Results

    Overview of GliomaPredict

    We implemented GliomaPredict as a web-based application that = assigns a=20 new patient to one of six predefined glioma subtypes using three = sets of=20 classifiers. The prediction is performed by running a supervised = PCA=20 analysis using classifier-based gene expression in a reference = set. The=20 prediction probability and distances are computed from the output = of PCA=20 analysis, and the new patient is accordingly assigned to a subtype = (Figure=20 1).=20 Using the projected mapping of the reference set classifiers to=20 discriminate between glioma subtypes, GliomaPredict offers a = flexible=20 solution, allowing users to utilize their laboratory and/or = microarray=20 platform specific sets of gene classifiers.

    Figure 1. Step-wise = workflow of the=20 GliomaPredict tool. Shaded area refers to functions and = features=20 included in the GliomaPredict tool. Specifically, our tool demands = a=20 transcriptomic .cel file of an unknown patient sample as input;=20 subsequently .cel file is automatically normalized. After = filtering=20 classifier-specific values, GliomaPredict performs a supervised = PCA=20 analysis, provides a graphical representation of the PCA results = and=20 returns the quantitative measures that assess the reliability of = the=20 underlying patient-designated classification.

    Data requirements, workflow and output

    GliomaPredict depends on a reference dataset to assign a new = patient to=20 a particular tumor subtype. Therefore, the reference dataset needs = to be=20 uploaded to the server during installation. It takes three steps = to create=20 a reference dataset: (i) profiling a set of glioma tumor arrays = using=20 Affymetrix HG-U133A, HG-U133AB or HG-U133 plus 2 platforms, (ii)=20 stratifying the arrays into the major subtypes (six subtypes in = our=20 classification) using classifiers [9], = (iii)=20 create a reference dataset file in MATLAB structure format that = contains=20 classifier expression of O/G, OA/OB and GA1/GA2/GB1/GB2 subtypes. = The=20 details for creating a reference set are available in the = GliomaPredict=20 manual. In addition, expression .cel files of new glioma patients = must be=20 uploaded to a server before the prediction analysis is run = (Additional=20 file 1,=20 Additional file 2). = The=20 .cel files will be normalized automatically after uploading and a = .txt=20 file containing normalized expression values is created and stored = into=20 GliomaPredict tool. A user can then select the new patient from = the=20 patient pulldown list for prediction. While a user chooses an = array for=20 classification, the classifier expression of that patient is = extracted and=20 merged into the reference dataset.

    GliomaPredict then performs a supervised PCA analysis using the = PRINCOMP function as implemented in MATLAB Statistics Toolbox, = which=20 sequentially selects new orthogonal coordinates, capturing as much = of the=20 remaining variation in the data as possible (Figure 2). = The=20 PCA analysis effectively reduces the dimensionality of the data = and the=20 first three uncorrelated coordinates from the PCAview module were = used to=20 provide a visual representation of the subtypes, indicating the = projection=20 of the unknown sample in predefined subtypes. In addition, the = output=20 includes the prediction probability and distance of the unknown = sample to=20 the centroid of the O and G groups of reference samples. Depending = on the=20 initial assessment, the patient's profile is further stratified = either=20 into the OA/OB subtypes or into one out of four G subtypes using a = specific set of subtype specific gene classifiers.

    Figure 2. User = interfaces,=20 prediction process and output examples of the GliomaPredict = tool.=20 Predicting the subtype of an unknown patient sample, GliomaPredict = provides a visual representation of the PCA of all reference = samples in=20 the subgroups. Indicating the location of an unknown patient = sample in=20 these data clouds, GliomaPredict calculates a probability that the = underlying sample is of a certain subgroup. In addition, = GliomaPredict=20 also accounts for a distance of the underlying sample to the = centroid of=20 the subgroups.

    Usability evaluation

    To ensure that the tool performs consistently and reliably, we = tested=20 GliomaPredict on two levels. First, we set up a core test dataset=20 consisting of 9 samples of new patients. The subtypes of these = samples=20 were assigned using PAMR, and results were cross-validated = extensively=20 using supervised hierarchical clustering and PCA to ensure the=20 re-assignments of these samples to subtypes are consistent with = the=20 previous prediction. PAMR, which has a shrunken centroid algorithm = implemented in [14], = was=20 originally used to derive the initial classifiers as reported by = Li et al.=20 [9]. = Our initial=20 test results indicated that the assignments of all the samples by = the=20 three methods were consistent. We then used these samples as = testers to=20 validate the performance consistency of GliomaPredict while = introducing=20 each of the main features or functions. For example, our original = data=20 were preprocessed using Windows version of dChip [15]. = To comply=20 with the Mac operating system and Linux platform, we chose to use = a gdChip=20 package for array normalization, which is an alternative version = of dChip=20 [16]. = Our=20 validation results using the core test set indicated that the data = normalized using gdChip package perform consistently compared to = those=20 normalized by the original Windows dChip in terms of the subtype=20 assignments. Secondly, we tested a subset of 61 samples with = assigned=20 subtypes that were predefined through an alternative approach = using NMF=20 and k-means stratification in our previous study [9].=20 GliomaPredict yielded a over 96% prediction accuracy when test = samples=20 were assigned to O/G main types, over 80% accuracy for predicting = OA/OB=20 subtypes and over 75% accuracy for predicting each of the four G = subtypes=20 (Table 1).

    Ta= ble=20 1. Usability evaluation of glioma subtype=20 predictions

    Current utilization

    GliomaPredict is currently running on the server of the = Neuro-Oncology=20 Branch (NOB) at the National Institutes of Health (NIH). = Physicians and=20 clinicians routinely use the tool to predict the subtype of glioma = patients. All newly generated expression .cel files are = automatically=20 uploaded to the server thereby making them readily available for = analysis=20 by the tool. Both clinicians and clinical/translational glioma = researchers=20 use the software to predict the subtypes of a given patient for = the=20 purpose of establishing the operative molecular pathways unique to = that=20 specific glioma subtype and for the purpose of identifying cohorts = of=20 patients most likely to respond to molecularly targeted agents = based on=20 our biological annotation of each subgroup.

    Discussion & Conclusions

    We have previously reported on the creation of a glioma = classification=20 system that includes six hierarchically nested subtypes and six = sets of=20 classifiers to define each subtype. To make this classification = schema=20 clinically useful, we implemented GliomaPredict that utilizes gene = expression profiles to reliably and automatically assign a glioma = patient=20 to one of the six predefined glioma subtypes. The tool is based on = a=20 supervised PCA analysis using classifiers that were derived = previously and=20 were extensively tested and validated. We have demonstrated that=20 GliomaPredict performs reliably in assigning a new patient to one = of the=20 six glioma subtypes with a mere click of a button on any desktop = computer=20 connected to the server. Since the reference set of samples and=20 subtype-specific gene classifiers can be taken from any given = laboratory,=20 we are confident that GliomaPredict will perform reliably across = different=20 laboratories and institutions.

    More sophisticated computational methodologies and strategies = will=20 continue to be developed to help interpret and elucidate the = underlying=20 biology from the ever-growing body of "-omic" data being generated = in=20 gliomas and other tumor types. Nevertheless, there is a pressing = need for=20 user-friendly tools for computational na=C3=AFve clinical and = translational=20 scientists if we are to begin to translate the advances in = molecular and=20 computational biology to the clinic and to patients. The ability = of a=20 clinical scientist to readily designate the molecular subtype of a = particular patient's tumor will allow the design of clinical = trials that=20 may enrich for patients more likely to benefit from a novel = molecularly=20 targeted therapeutic agent based on the signal transduction = pathway=20 activation status inherent in that tumor subgroup. It is important = to=20 note, however, that the clinical utility of glioma molecular = subtyping has=20 yet to be demonstrated. Nevertheless, it is hypothesized that this = type of=20 tumor-specific molecular data will ultimately lead to more = accurate=20 patient prognostication and possibly even patient-specific = therapy. The=20 ready ability to assign a given patient's tumor to a particular = subgroup=20 by the simple click of a button on a clinical computer, will aid = clinical=20 scientists in the testing of that hypothesis. Thus, GliomaPredict=20 represents a prototype of the kinds of clinically useful = computational=20 tools that may one day allow us to translate our rapidly growing = knowledge=20 of molecular and genetic biology toward the clinic and achieve the = paradigm of personalized medicine.

    Availability and Requirements

    Project name: GliomaPredict

    Project home page: GliomaPredict is available from this site: = https:/= /wiki.nci.nih.gov/display/NOBbioinf/GliomaPredict=20 webcite

    Operating system: Linux, Mac and Window OS

    Requirements: MATLAB version 7.9.0 or higher, Perl version = 5.8.8 or=20 higher

    Licence: a free, open source tool.

    Competing interests

    The authors declare that they have no competing = interests.

    Authors' contributions

    AL, designed and developed the system, and drafted the = manuscript. SB=20 designed and developed the algorithm for reliability assessment = and=20 developed the glioma product web interface. SB and YK handled the=20 GenePattern integration of the tool. HAF conceived, supervised and = guided=20 the project and assisted in the writing of the manuscript. All = authors=20 read and approved the final manuscript.

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TOP: -1px } .welcomeimgbmcbio { FLOAT: right; MARGIN: 0px 10px 2px 15px } .emailgrey { MARGIN-TOP: 4px; FONT-SIZE: 11px; WIDTH: 124px; COLOR: #818181; = LINE-HEIGHT: 14px; FONT-FAMILY: = Verdana,Geneva,Arial,Helvetica,sans-serif } #emailonclick { MARGIN-TOP: 4px; FONT-SIZE: 11px; WIDTH: 124px; LINE-HEIGHT: 14px; = FONT-FAMILY: Verdana,Geneva,Arial,Helvetica,sans-serif } .ulrssd { MARGIN-TOP: 0px; MARGIN-BOTTOM: 0px; LIST-STYLE-TYPE: disc } .ulrssc { LIST-STYLE-POSITION: inside; MARGIN: 0px 0px 0px 20px; LIST-STYLE-TYPE: = circle } .imgfirefoxmenu { FLOAT: right; WIDTH: 175px; HEIGHT: 223px } ------=_NextPart_000_0000_01CB3264.4D87E0A0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.biomedcentral.com/render/plugins//JmolFolder/Jmol.js /* Jmol 11.7 script library Jmol.js 15:32 06.12.2008 Bob Hanson checkbox heirarchy -- see = http://chemapps.stolaf.edu/jmol/docs/examples-11/check.htm based on: * * Copyright (C) 2004-2005 Miguel, Jmol Development, www.jmol.org * * Contact: hansonr@stolaf.edu * * This library is free software; you can redistribute it and/or * modify it under the terms of the GNU Lesser General Public * License as published by the Free Software Foundation; either * version 2.1 of the License, or (at your option) any later version. * * This library is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU * Lesser General Public License for more details. * * You should have received a copy of the GNU Lesser General Public * License along with this library; if not, write to the Free Software * Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA * 02111-1307 USA. */ // for documentation see www.jmol.org/jslibrary try{if(typeof(_jmol)!=3D"undefined")exit() // place "?NOAPPLET" on your command line to check applet control action = with a textarea // place "?JMOLJAR=3Dxxxxx" to use a specific jar file // bob hanson -- jmolResize(w,h) -- resizes absolutely or by percent (w = or h 0.5 means 50%) // bob hanson -- jmolEvaluate -- evaluates molecular math 8:37 AM = 2/23/2007 // bob hanson -- jmolScriptMessage -- returns all "scriptStatus" = messages 8:37 AM 2/23/2007 // bob hanson -- jmolScriptEcho -- returns all "scriptEcho" messages = 8:37 AM 2/23/2007 // bob hanson -- jmolScriptWait -- 11:31 AM 5/2/2006 // bob hanson -- remove trailing separatorHTML in radio groups -- 12:18 = PM 5/6/2006 // bob hanson -- adds support for dynamic DOM script nodes 7:04 AM = 5/19/2006 // bob hanson -- adds try/catch for wiki - multiple code passes 7:05 AM = 5/19/2006 // bob hanson -- auto-initiates to defaultdir/defaultjar -- change as = desired. // bob hanson -- adding save/restore orientation w/ and w/o delay 11:49 = AM 5/25/2006 // bob hanson -- adding AjaxJS service 11:16 AM 6/3/2006 // bob hanson -- fix for iframes not available for finding applet // bob hanson -- added applet fake ?NOAPPLET URL flag // bob hanson -- added jmolSetCallback(calbackName, funcName) 3:32 PM = 6/13/2006 // used PRIOR to jmolApplet() or jmolAppletInline() // added 4th array element in jmolRadioGroup -- title // added and id around link, checkbox, radio, menu // fixing AJAX loads for MSIE/Opera-Mozilla = incompatibility // -- renamed Jmol-11.js from Jmol-new.js; JmolApplet.jar = from JmolAppletProto.jar // renamed Jmol.js for Jmol 11 distribution // -- modified jmolRestoreOrientation() to be immediate, no = 1-second delay // bob hanson -- jmolScriptWait always returns a string -- 11:23 AM = 9/16/2006 // bh -- jmolCommandInput() // bh -- jmolSetTranslation(TF) -- forces translation even if = there might be message callback issues // bh -- minor fixes suggested by Angel // bh -- adds jmolSetSyncId() and jmolGetSyncId() // bh 3/2008 -- adds jmolAppendInlineScript() and = jmolAppendInlineArray() // bh 3/2008 -- fixes IE7 bug in relation to jmolLoadInlineArray() // bh 6/2008 -- adds jmolSetAppletWindow() // Angel H. 6/2008 -- added html " var t =3D ""=20 if (labelHtml.toLowerCase().indexOf("")>=3D0) { t +=3D eospan eospan =3D ""; } t +=3D "" = +eospan; if (_jmol.debugAlert) alert(t); return _jmolDocumentWrite(t); } function jmolStartNewRadioGroup() { ++_jmol.radioGroupCount; } function jmolRadioGroup(arrayOfRadioButtons, separatorHtml, groupName, = id, title) { /* array: [radio1,radio2,radio3...] where radioN =3D ["script","label",isSelected,"id","title"] */ _jmolInitCheck(); var type =3D typeof arrayOfRadioButtons; if (type !=3D "object" || type =3D=3D null || ! = arrayOfRadioButtons.length) { alert("invalid arrayOfRadioButtons"); return; } if (separatorHtml =3D=3D undefined || separatorHtml =3D=3D null) separatorHtml =3D "  "; var len =3D arrayOfRadioButtons.length; jmolStartNewRadioGroup(); if (!groupName) groupName =3D "jmolRadioGroup" + (_jmol.radioGroupCount - 1); var t =3D ""; for (var i =3D 0; i < len; ++i) { if (i =3D=3D len - 1) separatorHtml =3D ""; var radio =3D arrayOfRadioButtons[i]; type =3D typeof radio; if (type =3D=3D "object") { t +=3D _jmolRadio(radio[0], radio[1], radio[2], separatorHtml, = groupName, (radio.length > 3 ? radio[3]: (id ? id : groupName)+"_"+i), = (radio.length > 4 ? radio[4] : 0), title); } else { t +=3D _jmolRadio(radio, null, null, separatorHtml, groupName, (id = ? id : groupName)+"_"+i, title); } } t+=3D"" if (_jmol.debugAlert) alert(t); return _jmolDocumentWrite(t); } function jmolRadio(script, labelHtml, isChecked, separatorHtml, = groupName, id, title) { _jmolInitCheck(); if (_jmol.radioGroupCount =3D=3D 0) ++_jmol.radioGroupCount; var t =3D _jmolRadio(script, labelHtml, isChecked, separatorHtml, = groupName, (id ? id : groupName + "_" + _jmol.radioCount), title ? title = : 0); if (_jmol.debugAlert) alert(t); return _jmolDocumentWrite(t); } function jmolLink(script, label, id, title) { _jmolInitCheck(); if (id =3D=3D undefined || id =3D=3D null) id =3D "jmolLink" + _jmol.linkCount; if (label =3D=3D undefined || label =3D=3D null) label =3D script.substring(0, 32); ++_jmol.linkCount; var scriptIndex =3D _jmolAddScript(script); var t =3D "" + label + ""; if (_jmol.debugAlert) alert(t); return _jmolDocumentWrite(t); } function jmolCommandInput(label, size, id, title) { _jmolInitCheck(); if (id =3D=3D undefined || id =3D=3D null) id =3D "jmolCmd" + _jmol.cmdCount; if (label =3D=3D undefined || label =3D=3D null) label =3D "Execute"; if (size =3D=3D undefined || isNaN(size)) size =3D 60; ++_jmol.cmdCount; var t =3D ""; if (_jmol.debugAlert) alert(t); return _jmolDocumentWrite(t); } function jmolMenu(arrayOfMenuItems, size, id, title) { _jmolInitCheck(); if (id =3D=3D undefined || id =3D=3D null) id =3D "jmolMenu" + _jmol.menuCount; ++_jmol.menuCount; var type =3D typeof arrayOfMenuItems; if (type !=3D null && type =3D=3D "object" && arrayOfMenuItems.length) = { var len =3D arrayOfMenuItems.length; if (typeof size !=3D "number" || size =3D=3D 1) size =3D null; else if (size < 0) size =3D len; var sizeText =3D size ? " size=3D'" + size + "' " : ""; var t =3D "" if (labelHtml.toLowerCase().indexOf("")>=3D0) { t +=3D eospan eospan =3D ""; } t +=3D "" +eospan = + separatorHtml; return t; } function _jmolFindApplet(target) { // first look for the target in the current window var applet =3D _jmolFindAppletInWindow(_jmol.appletWindow !=3D null ? = _jmol.appletWindow : window, target); // THEN look for the target in child frames if (applet =3D=3D undefined) applet =3D _jmolSearchFrames(window, target); // FINALLY look for the target in sibling frames if (applet =3D=3D undefined) applet =3D _jmolSearchFrames(top, target); // look starting in top = frame return applet; } function _jmolGetApplet(targetSuffix){ var target =3D "jmolApplet" + (targetSuffix ? targetSuffix : "0"); var applet =3D _jmolFindApplet(target); if (applet) return applet if(!_jmol.alerted)alert("could not find applet " + target); _jmol.alerted =3D true; return null } function _jmolSearchFrames(win, target) { var applet; var frames =3D win.frames; if (frames && frames.length) { // look in all the frames below this = window try{ for (var i =3D 0; i < frames.length; ++i) { applet =3D _jmolSearchFrames(frames[i], target); if (applet) return applet; } }catch(e) { if (_jmol.debugAlert) alert("Jmol.js _jmolSearchFrames cannot access " + win.name + = ".frame[" + i + "] consider using jmolSetAppletWindow()")=20 } } return applet =3D _jmolFindAppletInWindow(win, target) } function _jmolFindAppletInWindow(win, target) { var doc =3D win.document; // getElementById fails on MacOSX Safari & Mozilla=09 if (_jmol.useHtml4Object || _jmol.useIEObject) return doc.getElementById(target); else if (doc.applets) return doc.applets[target]; else return doc[target];=20 } function _jmolAddScript(script) { if (! script) return 0; var index =3D _jmol.scripts.length; _jmol.scripts[index] =3D script; return index; } function _jmolClick(scriptIndex, targetSuffix, elementClicked) { _jmol.element =3D elementClicked; jmolScript(_jmol.scripts[scriptIndex], targetSuffix); } function _jmolMenuSelected(menuObject, targetSuffix) { var scriptIndex =3D menuObject.value; if (scriptIndex !=3D undefined) { jmolScript(_jmol.scripts[scriptIndex], targetSuffix); return; } var len =3D menuObject.length; if (typeof len =3D=3D "number") { for (var i =3D 0; i < len; ++i) { if (menuObject[i].selected) { _jmolClick(menuObject[i].value, targetSuffix); return; } } } alert("?Que? menu selected bug #8734"); } _jmol.checkboxMasters =3D {}; _jmol.checkboxItems =3D {}; function jmolSetCheckboxGroup(chkMaster,chkBox) { var id =3D chkMaster; if(typeof(id)=3D=3D"number")id =3D "jmolCheckbox" + id; chkMaster =3D document.getElementById(id); if (!chkMaster)alert("jmolSetCheckboxGroup: master checkbox not found: = " + id); var m =3D _jmol.checkboxMasters[id] =3D {}; m.chkMaster =3D chkMaster; m.chkGroup =3D {}; for (var i =3D 1; i < arguments.length; i++){ var id =3D arguments[i]; if(typeof(id)=3D=3D"number")id =3D "jmolCheckbox" + id; checkboxItem =3D document.getElementById(id); if (!checkboxItem)alert("jmolSetCheckboxGroup: group checkbox not = found: " + id); m.chkGroup[id] =3D checkboxItem; _jmol.checkboxItems[id] =3D m; } } function _jmolNotifyMaster(m){ //called when a group item is checked var allOn =3D true; var allOff =3D true; for (var chkBox in m.chkGroup){ if(m.chkGroup[chkBox].checked) allOff =3D false; else allOn =3D false; } if (allOn)m.chkMaster.checked =3D true;=09 if (allOff)m.chkMaster.checked =3D false; if ((allOn || allOff) && _jmol.checkboxItems[m.chkMaster.id]) _jmolNotifyMaster(_jmol.checkboxItems[m.chkMaster.id]) } function _jmolNotifyGroup(m, isOn){ //called when a master item is checked for (var chkBox in m.chkGroup){ var item =3D m.chkGroup[chkBox] item.checked =3D isOn; if (_jmol.checkboxMasters[item.id]) _jmolNotifyGroup(_jmol.checkboxMasters[item.id], isOn) } } function _jmolCbClick(ckbox, whenChecked, whenUnchecked, targetSuffix) { _jmol.control =3D ckbox _jmolClick(ckbox.checked ? whenChecked : whenUnchecked, targetSuffix); if(_jmol.checkboxMasters[ckbox.id]) _jmolNotifyGroup(_jmol.checkboxMasters[ckbox.id], ckbox.checked) if(_jmol.checkboxItems[ckbox.id]) _jmolNotifyMaster(_jmol.checkboxItems[ckbox.id]) } function _jmolCbOver(ckbox, whenChecked, whenUnchecked) { window.status =3D _jmol.scripts[ckbox.checked ? whenUnchecked : = whenChecked]; } function _jmolMouseOver(scriptIndex) { window.status =3D _jmol.scripts[scriptIndex]; } function _jmolMouseOut() { window.status =3D " "; return true; } function _jmolSetCodebase(codebase) { _jmol.codebase =3D codebase ? codebase : "."; if (_jmol.debugAlert) alert("jmolCodebase=3D" + _jmol.codebase); } function _jmolOnloadResetForms() { // must be evaluated ONLY once _jmol.previousOnloadHandler =3D window.onload; window.onload =3D function() { with (_jmol) { if (buttonCount+checkboxCount+menuCount+radioCount+radioGroupCount = > 0) { var forms =3D document.forms; for (var i =3D forms.length; --i >=3D 0; ) forms[i].reset(); } if (previousOnloadHandler) previousOnloadHandler(); } } } //////////////////////////////////// /////extensions for getProperty///// //////////////////////////////////// function _jmolEvalJSON(s,key){ s=3Ds+"" if(!s)return [] if(s.charAt(0)!=3D"{"){ if(s.indexOf(" | ")>=3D0)s=3Ds.replace(/\ \|\ /g, "\n") return s } var A =3D eval("("+s+")") if(!A)return if(key && A[key])A=3DA[key] return A } function _jmolEnumerateObject(A,key){ var sout=3D"" if(typeof(A) =3D=3D "string" && A!=3D"null"){ sout+=3D"\n"+key+"=3D\""+A+"\"" }else if(!isNaN(A)||A=3D=3Dnull){ sout+=3D"\n"+key+"=3D"+(A+""=3D=3D""?"null":A) }else if(A.length){ sout+=3Dkey+"=3D[]" for(var i=3D0;ib[0]?-1:0) } function _jmolSortMessages(A){ if(!A || typeof(A)!=3D"object")return [] var B =3D [] for(var i=3DA.length-1;i>=3D0;i--)for(var = j=3D0;j=3D0;) for(var j=3D0;j< Ret[i].length;j++) s+=3DRet[i][j]+"\n" return s } function jmolScriptWaitOutput(script, targetSuffix) { if(!targetSuffix)targetSuffix=3D"0" var ret =3D "" try{ if (script) { _jmolCheckBrowser(); var applet=3D_jmolGetApplet(targetSuffix); if (applet) ret +=3D applet.scriptWaitOutput(script); } }catch(e){ } return ret; } function jmolEvaluate(molecularMath, targetSuffix) { //carries out molecular math on a model if(!targetSuffix)targetSuffix=3D"0" var result =3D "" + jmolGetPropertyAsJavaObject("evaluate", = molecularMath, targetSuffix); var s =3D result.replace(/\-*\d+/,"") if (s =3D=3D "" && !isNaN(parseInt(result)))return parseInt(result); var s =3D result.replace(/\-*\d*\.\d*/,"") if (s =3D=3D "" && !isNaN(parseFloat(result)))return = parseFloat(result); return result; } function jmolScriptEcho(script, targetSuffix) { // returns a newline-separated list of all echos from a script if(!targetSuffix)targetSuffix=3D"0" var Ret=3DjmolScriptWaitAsArray(script, targetSuffix) var s =3D "" for(var i=3DRet.length;--i>=3D0;) for(var j=3DRet[i].length;--j>=3D0;) if (Ret[i][j][1] =3D=3D "scriptEcho")s+=3DRet[i][j][3]+"\n" return s.replace(/ \| /g, "\n") } function jmolScriptMessage(script, targetSuffix) { // returns a newline-separated list of all messages from a script, = ending with "script completed\n" if(!targetSuffix)targetSuffix=3D"0" var Ret=3DjmolScriptWaitAsArray(script, targetSuffix) var s =3D "" for(var i=3DRet.length;--i>=3D0;) for(var j=3DRet[i].length;--j>=3D0;) if (Ret[i][j][1] =3D=3D "scriptStatus")s+=3DRet[i][j][3]+"\n" return s.replace(/ \| /g, "\n") } function jmolScriptWaitAsArray(script, targetSuffix) { var ret =3D "" try{ = jmolGetStatus("scriptEcho,scriptMessage,scriptStatus,scriptError",targetS= uffix) if (script) { _jmolCheckBrowser(); var applet=3D_jmolGetApplet(targetSuffix); if (applet) ret +=3D applet.scriptWait(script); ret =3D _jmolEvalJSON(ret,"jmolStatus") if(typeof ret =3D=3D "object") return ret } }catch(e){ } return [[ret]] } //////////// save/restore orientation ///////////// function jmolSaveOrientation(id, targetSuffix) { =20 if(!targetSuffix)targetSuffix=3D"0" return _jmol["savedOrientation"+id] =3D = jmolGetPropertyAsArray("orientationInfo","info",targetSuffix).moveTo } function jmolRestoreOrientation(id, targetSuffix) { if(!targetSuffix)targetSuffix=3D"0" var s=3D_jmol["savedOrientation"+id] if (!s || s =3D=3D "")return s=3Ds.replace(/1\.0/,"0") return jmolScriptWait(s,targetSuffix) } function jmolRestoreOrientationDelayed(id, delay, targetSuffix) { if(arguments.length < 2)delay=3D1; if(!targetSuffix)targetSuffix=3D"0" var s=3D_jmol["savedOrientation"+id] if (!s || s =3D=3D "")return s=3Ds.replace(/1\.0/,delay) return jmolScriptWait(s,targetSuffix) } //////////// add parameter ///////////// /* * for adding callbacks or other parameters. Use: jmolSetDocument(0) var s=3D jmolApplet(....) s =3D jmolAppletAddParam(s,"messageCallback", "myFunctionName") document.write(s) jmolSetDocument(document) // if you want to then write buttons and = such normally =20 */ function jmolAppletAddParam(appletCode,name,value){ if(value =3D=3D "")return appletCode return appletCode.replace(/\\n=3D0){ jmolApplet =3D function(w){ var s=3D"" +"
    " +"Applet would be here" +"

    " +"

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(e.pageY-this.offset.click.top>this.containment[3]){c=3Dthis.containment[= 3]+this.offset.click.top}}if(h.grid){var = g=3Dthis.originalPageY+Math.round((c-this.originalPageY)/h.grid[1])*h.gri= d[1];c=3Dthis.containment?(!(g-this.offset.click.topthis.containment[3])?g:(!(g-this.offset.click.to= pthis.containment[2])?f:(!(f-this.offset.click.= left
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"x"){if((c.overflowOffset.top+c.scrollParent[0].offsetHeight)-d.pageY=3D0;v--){var = s=3Dg.snapElements[v].left,n=3Ds+g.snapElements[v].width,m=3Dg.snapElemen= ts[v].top,A=3Dm+g.snapElements[v].height;if(!((s-y=3Dp&&n<=3Dk)||(m>=3Dp&&m<=3Dk)||(nk)= )&&((e>=3Dg&&e<=3Dc)||(d>=3Dg&&d<=3Dc)||(ec));break;default:return = false;break}};a.ui.ddmanager=3D{current:null,droppables:{"default":[]},pr= epareOffsets:function(e,g){var = b=3Da.ui.ddmanager.droppables[e.options.scope];var f=3Dg?g.type:null;var = h=3D(e.currentItem||e.element).find(":data(droppable)").andSelf();droppab= lesLoop:for(var = d=3D0;d').css({position:this.element.css("position"),width:this.e= lement.outerWidth(),height:this.element.outerHeight(),top:this.element.cs= s("top"),left:this.element.css("left")}));this.element=3Dthis.element.par= ent().data("resizable",this.element.data("resizable"));this.elementIsWrap= per=3Dtrue;this.element.css({marginLeft:this.originalElement.css("marginL= eft"),marginTop:this.originalElement.css("marginTop"),marginRight:this.or= iginalElement.css("marginRight"),marginBottom:this.originalElement.css("m= arginBottom")});this.originalElement.css({marginLeft:0,marginTop:0,margin= Right:0,marginBottom:0});this.originalResizeStyle=3Dthis.originalElement.= css("resize");this.originalElement.css("resize","none");this._proportiona= llyResizeElements.push(this.originalElement.css({position:"static",zoom:1= ,display:"block"}));this.originalElement.css({margin:this.originalElement= .css("margin")});this._proportionallyResize()}this.handles=3Dj.handles||(= !c(".ui-resizable-handle",this.element).length?"e,s,se":{n:".ui-resizable= -n",e:".ui-resizable-e",s:".ui-resizable-s",w:".ui-resizable-w",se:".ui-r= esizable-se",sw:".ui-resizable-sw",ne:".ui-resizable-ne",nw:".ui-resizabl= e-nw"});if(this.handles.constructor=3D=3DString){if(this.handles=3D=3D"al= l"){this.handles=3D"n,e,s,w,se,sw,ne,nw"}var = k=3Dthis.handles.split(",");this.handles=3D{};for(var 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f=3Da(document.createElement(b.currentItem[0].nodeName)).addClass(c||b.cu= rrentItem[0].className+" = ui-sortable-placeholder").removeClass("ui-sortable-helper")[0];if(!c){f.s= tyle.visibility=3D"hidden"}return = f},update:function(f,g){if(c&&!e.forcePlaceholderSize){return}if(!g.heigh= t()){g.height(b.currentItem.innerHeight()-parseInt(b.currentItem.css("pad= dingTop")||0,10)-parseInt(b.currentItem.css("paddingBottom")||0,10))}if(!= g.width()){g.width(b.currentItem.innerWidth()-parseInt(b.currentItem.css(= "paddingLeft")||0,10)-parseInt(b.currentItem.css("paddingRight")||0,10))}= }}}b.placeholder=3Da(e.placeholder.element.call(b.element,b.currentItem))= ;b.currentItem.after(b.placeholder);e.placeholder.update(b,b.placeholder)= },_contactContainers:function(d){for(var = c=3Dthis.containers.length-1;c>=3D0;c--){if(this._intersectsWith(this.con= tainers[c].containerCache)){if(!this.containers[c].containerCache.over){i= f(this.currentContainer!=3Dthis.containers[c]){var h=3D10000;var = 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function(h){g._trigger("update",h,this._uiHash(this))}}).call(this,this.c= ontainers[c]))}}}for(var = c=3Dthis.containers.length-1;c>=3D0;c--){if(!e){f.push((function(g){retur= n = function(h){g._trigger("deactivate",h,this._uiHash(this))}}).call(this,th= is.containers[c]))}if(this.containers[c].containerCache.over){f.push((fun= ction(g){return = function(h){g._trigger("out",h,this._uiHash(this))}}).call(this,this.cont= ainers[c]));this.containers[c].containerCache.over=3D0}}if(this._storedCu= rsor){a("body").css("cursor",this._storedCursor)}if(this._storedOpacity){= this.helper.css("opacity",this._storedOpacity)}if(this._storedZIndex){thi= s.helper.css("zIndex",this._storedZIndex=3D=3D"auto"?"":this._storedZInde= x)}this.dragging=3Dfalse;if(this.cancelHelperRemoval){if(!e){this._trigge= r("beforeStop",d,this._uiHash());for(var = c=3D0;c = *",opacity:false,placeholder:false,revert:false,scroll:true,scrollSensiti= 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ldren("li").addClass("ui-accordion-li-fix")}this.headers=3Dthis.element.f= ind(d.header).addClass("ui-accordion-header ui-helper-reset = ui-state-default = ui-corner-all").bind("mouseenter.accordion",function(){a(this).addClass("= ui-state-hover")}).bind("mouseleave.accordion",function(){a(this).removeC= lass("ui-state-hover")}).bind("focus.accordion",function(){a(this).addCla= ss("ui-state-focus")}).bind("blur.accordion",function(){a(this).removeCla= ss("ui-state-focus")});this.headers.next().addClass("ui-accordion-content= ui-helper-reset ui-widget-content = ui-corner-bottom");this.active=3Dthis._findActive(this.active||d.active).= toggleClass("ui-state-default").toggleClass("ui-state-active").toggleClas= s("ui-corner-all").toggleClass("ui-corner-top");this.active.next().addCla= ss("ui-accordion-content-active");a("").addClass("ui-icon = "+d.icons.header).prependTo(this.headers);this.active.find(".ui-icon").to= ggleClass(d.icons.header).toggleClass(d.icons.headerSelected);if(a.browse= r.msie){this.element.find("a").css("zoom","1")}this.resize();this.element= .attr("role","tablist");this.headers.attr("role","tab").bind("keydown",fu= nction(e){return = b._keydown(e)}).next().attr("role","tabpanel");this.headers.not(this.acti= ve||"").attr("aria-expanded","false").attr("tabIndex","-1").next().hide()= ;if(!this.active.length){this.headers.eq(0).attr("tabIndex","0")}else{thi= s.active.attr("aria-expanded","true").attr("tabIndex","0")}if(!a.browser.= safari){this.headers.find("a").attr("tabIndex","-1")}if(d.event){this.hea= ders.bind((d.event)+".accordion",function(e){return = b._clickHandler.call(b,e,this)})}},destroy:function(){var = c=3Dthis.options;this.element.removeClass("ui-accordion ui-widget = ui-helper-reset").removeAttr("role").unbind(".accordion").removeData("acc= ordion");this.headers.unbind(".accordion").removeClass("ui-accordion-head= er ui-helper-reset ui-state-default ui-corner-all ui-state-active = ui-corner-top").removeAttr("role").removeAttr("aria-expanded").removeAttr= ("tabindex");this.headers.find("a").removeAttr("tabindex");this.headers.c= hildren(".ui-icon").remove();var = b=3Dthis.headers.next().css("display","").removeAttr("role").removeClass(= "ui-helper-reset ui-widget-content ui-corner-bottom ui-accordion-content = ui-accordion-content-active");if(c.autoHeight||c.fillHeight){b.css("heigh= t","")}},_setData:function(b,c){if(b=3D=3D"alwaysOpen"){b=3D"collapsible"= ;c=3D!c}a.widget.prototype._setData.apply(this,arguments)},_keydown:funct= ion(e){var = g=3Dthis.options,f=3Da.ui.keyCode;if(g.disabled||e.altKey||e.ctrlKey){ret= urn}var d=3Dthis.headers.length;var b=3Dthis.headers.index(e.target);var = c=3Dfalse;switch(e.keyCode){case f.RIGHT:case = f.DOWN:c=3Dthis.headers[(b+1)%d];break;case f.LEFT:case = f.UP:c=3Dthis.headers[(b-1+d)%d];break;case f.SPACE:case f.ENTER:return = this._clickHandler({target:e.target},e.target)}if(c){a(e.target).attr("ta= bIndex","-1");a(c).attr("tabIndex","0");c.focus();return false}return = true},resize:function(){var = e=3Dthis.options,d;if(e.fillSpace){if(a.browser.msie){var = b=3Dthis.element.parent().css("overflow");this.element.parent().css("over= flow","hidden")}d=3Dthis.element.parent().height();if(a.browser.msie){thi= s.element.parent().css("overflow",b)}this.headers.each(function(){d-=3Da(= this).outerHeight()});var = c=3D0;this.headers.next().each(function(){c=3DMath.max(c,a(this).innerHei= ght()-a(this).height())}).height(Math.max(0,d-c)).css("overflow","auto")}= else{if(e.autoHeight){d=3D0;this.headers.next().each(function(){d=3DMath.= max(d,a(this).outerHeight())}).height(d)}}},activate:function(b){var = c=3Dthis._findActive(b)[0];this._clickHandler({target:c},c)},_findActive:= function(b){return b?typeof = b=3D=3D"number"?this.headers.filter(":eq("+b+")"):this.headers.not(this.h= eaders.not(b)):b=3D=3D=3Dfalse?a([]):this.headers.filter(":eq(0)")},_clic= kHandler:function(b,f){var d=3Dthis.options;if(d.disabled){return = false}if(!b.target&&d.collapsible){this.active.removeClass("ui-state-acti= ve ui-corner-top").addClass("ui-state-default = ui-corner-all").find(".ui-icon").removeClass(d.icons.headerSelected).addC= lass(d.icons.header);this.active.next().addClass("ui-accordion-content-ac= tive");var = h=3Dthis.active.next(),e=3D{options:d,newHeader:a([]),oldHeader:d.active,= newContent:a([]),oldContent:h},c=3D(this.active=3Da([]));this._toggle(c,h= ,e);return false}var g=3Da(b.currentTarget||f);var = i=3Dg[0]=3D=3Dthis.active[0];if(this.running||(!d.collapsible&&i)){return= false}this.active.removeClass("ui-state-active = ui-corner-top").addClass("ui-state-default = ui-corner-all").find(".ui-icon").removeClass(d.icons.headerSelected).addC= lass(d.icons.header);this.active.next().addClass("ui-accordion-content-ac= tive");if(!i){g.removeClass("ui-state-default = ui-corner-all").addClass("ui-state-active = ui-corner-top").find(".ui-icon").removeClass(d.icons.header).addClass(d.i= cons.headerSelected);g.next().addClass("ui-accordion-content-active")}var= = c=3Dg.next(),h=3Dthis.active.next(),e=3D{options:d,newHeader:i&&d.collaps= ible?a([]):g,oldHeader:this.active,newContent:i&&d.collapsible?a([]):c.fi= nd("> *"),oldContent:h.find("> = *")},j=3Dthis.headers.index(this.active[0])>this.headers.index(g[0]);this= .active=3Di?a([]):g;this._toggle(c,h,e,i,j);return = false},_toggle:function(b,i,g,j,k){var = d=3Dthis.options,m=3Dthis;this.toShow=3Db;this.toHide=3Di;this.data=3Dg;v= ar c=3Dfunction(){if(!m){return}return = m._completed.apply(m,arguments)};this._trigger("changestart",null,this.da= ta);this.running=3Di.size()=3D=3D=3D0?b.size():i.size();if(d.animated){va= r = f=3D{};if(d.collapsible&&j){f=3D{toShow:a([]),toHide:i,complete:c,down:k,= autoHeight:d.autoHeight||d.fillSpace}}else{f=3D{toShow:b,toHide:i,complet= e:c,down:k,autoHeight:d.autoHeight||d.fillSpace}}if(!d.proxied){d.proxied= =3Dd.animated}if(!d.proxiedDuration){d.proxiedDuration=3Dd.duration}d.ani= mated=3Da.isFunction(d.proxied)?d.proxied(f):d.proxied;d.duration=3Da.isF= unction(d.proxiedDuration)?d.proxiedDuration(f):d.proxiedDuration;var = l=3Da.ui.accordion.animations,e=3Dd.duration,h=3Dd.animated;if(!l[h]){l[h= ]=3Dfunction(n){this.slide(n,{easing:h,duration:e||700})}}l[h](f)}else{if= (d.collapsible&&j){b.toggle()}else{i.hide();b.show()}c(true)}i.prev().att= r("aria-expanded","false").attr("tabIndex","-1").blur();b.prev().attr("ar= ia-expanded","true").attr("tabIndex","0").focus()},_completed:function(b)= {var = c=3Dthis.options;this.running=3Db?0:--this.running;if(this.running){retur= n}if(c.clearStyle){this.toShow.add(this.toHide).css({height:"",overflow:"= "})}this._trigger("change",null,this.data)}});a.extend(a.ui.accordion,{ve= rsion:"1.7.1",defaults:{active:null,alwaysOpen:true,animated:"slide",auto= Height:true,clearStyle:false,collapsible:false,event:"click",fillSpace:fa= lse,header:"> li > :first-child,> = :not(li):even",icons:{header:"ui-icon-triangle-1-e",headerSelected:"ui-ic= on-triangle-1-s"},navigation:false,navigationFilter:function(){return = this.href.toLowerCase()=3D=3Dlocation.href.toLowerCase()}},animations:{sl= ide:function(j,h){j=3Da.extend({easing:"swing",duration:300},j,h);if(!j.t= oHide.size()){j.toShow.animate({height:"show"},j);return}if(!j.toShow.siz= e()){j.toHide.animate({height:"hide"},j);return}var = c=3Dj.toShow.css("overflow"),g,d=3D{},f=3D{},e=3D["height","paddingTop","= paddingBottom"],b;var = i=3Dj.toShow;b=3Di[0].style.width;i.width(parseInt(i.parent().width(),10)= -parseInt(i.css("paddingLeft"),10)-parseInt(i.css("paddingRight"),10)-(pa= rseInt(i.css("borderLeftWidth"),10)||0)-(parseInt(i.css("borderRightWidth= "),10)||0));a.each(e,function(k,m){f[m]=3D"hide";var = l=3D(""+a.css(j.toShow[0],m)).match(/^([\d+-.]+)(.*)$/);d[m]=3D{value:l[1= ],unit:l[2]||"px"}});j.toShow.css({height:0,overflow:"hidden"}).show();j.= toHide.filter(":hidden").each(j.complete).end().filter(":visible").animat= e(f,{step:function(k,l){if(l.prop=3D=3D"height"){g=3D(l.now-l.start)/(l.e= nd-l.start)}j.toShow[0].style[l.prop]=3D(g*d[l.prop].value)+d[l.prop].uni= t},duration:j.duration,easing:j.easing,complete:function(){if(!j.autoHeig= ht){j.toShow.css("height","")}j.toShow.css("width",b);j.toShow.css({overf= low:c});j.complete()}})},bounceslide:function(b){this.slide(b,{easing:b.d= own?"easeOutBounce":"swing",duration:b.down?1000:200})},easeslide:functio= n(b){this.slide(b,{easing:"easeinout",duration:700})}}})})(jQuery);;/* * jQuery UI Dialog 1.7.1 * * Copyright (c) 2009 AUTHORS.txt (http://jqueryui.com/about) * Dual licensed under the MIT (MIT-LICENSE.txt) * and GPL (GPL-LICENSE.txt) licenses. * * http://docs.jquery.com/UI/Dialog * * Depends: * ui.core.js * ui.draggable.js * ui.resizable.js */ (function(c){var = b=3D{dragStart:"start.draggable",drag:"drag.draggable",dragStop:"stop.dra= ggable",maxHeight:"maxHeight.resizable",minHeight:"minHeight.resizable",m= axWidth:"maxWidth.resizable",minWidth:"minWidth.resizable",resizeStart:"s= tart.resizable",resize:"drag.resizable",resizeStop:"stop.resizable"},a=3D= "ui-dialog ui-widget ui-widget-content ui-corner-all = ";c.widget("ui.dialog",{_init:function(){this.originalTitle=3Dthis.elemen= t.attr("title");var = l=3Dthis,m=3Dthis.options,j=3Dm.title||this.originalTitle||" ",e=3Dc= .ui.dialog.getTitleId(this.element),k=3D(this.uiDialog=3Dc("
    ")).app= endTo(document.body).hide().addClass(a+m.dialogClass).css({position:"abso= lute",overflow:"hidden",zIndex:m.zIndex}).attr("tabIndex",-1).css("outlin= e",0).keydown(function(n){(m.closeOnEscape&&n.keyCode&&n.keyCode=3D=3Dc.u= i.keyCode.ESCAPE&&l.close(n))}).attr({role:"dialog","aria-labelledby":e})= .mousedown(function(n){l.moveToTop(false,n)}),g=3Dthis.element.show().rem= oveAttr("title").addClass("ui-dialog-content = ui-widget-content").appendTo(k),f=3D(this.uiDialogTitlebar=3Dc("
    ")).addClass("ui-dialog-titlebar ui-widget-header ui-corner-all = ui-helper-clearfix").prependTo(k),i=3Dc('').addClass("ui-dialog-titlebar-close = ui-corner-all").attr("role","button").hover(function(){i.addClass("ui-sta= te-hover")},function(){i.removeClass("ui-state-hover")}).focus(function()= {i.addClass("ui-state-focus")}).blur(function(){i.removeClass("ui-state-f= ocus")}).mousedown(function(n){n.stopPropagation()}).click(function(n){l.= close(n);return = false}).appendTo(f),h=3D(this.uiDialogTitlebarCloseText=3Dc("")).a= ddClass("ui-icon = ui-icon-closethick").text(m.closeText).appendTo(i),d=3Dc("").addCl= ass("ui-dialog-title").attr("id",e).html(j).prependTo(f);f.find("*").add(= f).disableSelection();(m.draggable&&c.fn.draggable&&this._makeDraggable()= );(m.resizable&&c.fn.resizable&&this._makeResizable());this._createButton= s(m.buttons);this._isOpen=3Dfalse;(m.bgiframe&&c.fn.bgiframe&&k.bgiframe(= ));(m.autoOpen&&this.open())},destroy:function(){(this.overlay&&this.over= lay.destroy());this.uiDialog.hide();this.element.unbind(".dialog").remove= Data("dialog").removeClass("ui-dialog-content = ui-widget-content").hide().appendTo("body");this.uiDialog.remove();(this.= originalTitle&&this.element.attr("title",this.originalTitle))},close:func= tion(e){var = d=3Dthis;if(false=3D=3D=3Dd._trigger("beforeclose",e)){return}(d.overlay&= &d.overlay.destroy());d.uiDialog.unbind("keypress.ui-dialog");(d.options.= hide?d.uiDialog.hide(d.options.hide,function(){d._trigger("close",e)}):d.= uiDialog.hide()&&d._trigger("close",e));c.ui.dialog.overlay.resize();d._i= sOpen=3Dfalse},isOpen:function(){return = this._isOpen},moveToTop:function(f,e){if((this.options.modal&&!f)||(!this= .options.stack&&!this.options.modal)){return = this._trigger("focus",e)}if(this.options.zIndex>c.ui.dialog.maxZ){c.ui.di= alog.maxZ=3Dthis.options.zIndex}(this.overlay&&this.overlay.$el.css("z-in= dex",c.ui.dialog.overlay.maxZ=3D++c.ui.dialog.maxZ));var = d=3D{scrollTop:this.element.attr("scrollTop"),scrollLeft:this.element.att= r("scrollLeft")};this.uiDialog.css("z-index",++c.ui.dialog.maxZ);this.ele= ment.attr(d);this._trigger("focus",e)},open:function(){if(this._isOpen){r= eturn}var e=3Dthis.options,d=3Dthis.uiDialog;this.overlay=3De.modal?new = c.ui.dialog.overlay(this):null;(d.next().length&&d.appendTo("body"));this= ._size();this._position(e.position);d.show(e.show);this.moveToTop(true);(= e.modal&&d.bind("keypress.ui-dialog",function(h){if(h.keyCode!=3Dc.ui.key= Code.TAB){return}var = g=3Dc(":tabbable",this),i=3Dg.filter(":first")[0],f=3Dg.filter(":last")[0= ];if(h.target=3D=3Df&&!h.shiftKey){setTimeout(function(){i.focus()},1)}el= se{if(h.target=3D=3Di&&h.shiftKey){setTimeout(function(){f.focus()},1)}}}= ));c([]).add(d.find(".ui-dialog-content = :tabbable:first")).add(d.find(".ui-dialog-buttonpane = :tabbable:first")).add(d).filter(":first").focus();this._trigger("open");= this._isOpen=3Dtrue},_createButtons:function(g){var = f=3Dthis,d=3Dfalse,e=3Dc("
    ").addClass("ui-dialog-buttonpane = ui-widget-content = ui-helper-clearfix");this.uiDialog.find(".ui-dialog-buttonpane").remove()= ;(typeof g=3D=3D"object"&&g!=3D=3Dnull&&c.each(g,function(){return = !(d=3Dtrue)}));if(d){c.each(g,function(h,i){c('').addClass("ui-state-default = ui-corner-all").text(h).click(function(){i.apply(f.element[0],arguments)}= ).hover(function(){c(this).addClass("ui-state-hover")},function(){c(this)= .removeClass("ui-state-hover")}).focus(function(){c(this).addClass("ui-st= ate-focus")}).blur(function(){c(this).removeClass("ui-state-focus")}).app= endTo(e)});e.appendTo(this.uiDialog)}},_makeDraggable:function(){var = d=3Dthis,f=3Dthis.options,e;this.uiDialog.draggable({cancel:".ui-dialog-c= ontent",handle:".ui-dialog-titlebar",containment:"document",start:functio= n(){e=3Df.height;c(this).height(c(this).height()).addClass("ui-dialog-dra= gging");(f.dragStart&&f.dragStart.apply(d.element[0],arguments))},drag:fu= nction(){(f.drag&&f.drag.apply(d.element[0],arguments))},stop:function(){= c(this).removeClass("ui-dialog-dragging").height(e);(f.dragStop&&f.dragSt= op.apply(d.element[0],arguments));c.ui.dialog.overlay.resize()}})},_makeR= esizable:function(g){g=3D(g=3D=3D=3Dundefined?this.options.resizable:g);v= ar d=3Dthis,f=3Dthis.options,e=3Dtypeof = g=3D=3D"string"?g:"n,e,s,w,se,sw,ne,nw";this.uiDialog.resizable({cancel:"= .ui-dialog-content",alsoResize:this.element,maxWidth:f.maxWidth,maxHeight= :f.maxHeight,minWidth:f.minWidth,minHeight:f.minHeight,start:function(){c= (this).addClass("ui-dialog-resizing");(f.resizeStart&&f.resizeStart.apply= (d.element[0],arguments))},resize:function(){(f.resize&&f.resize.apply(d.= element[0],arguments))},handles:e,stop:function(){c(this).removeClass("ui= -dialog-resizing");f.height=3Dc(this).height();f.width=3Dc(this).width();= (f.resizeStop&&f.resizeStop.apply(d.element[0],arguments));c.ui.dialog.ov= erlay.resize()}}).find(".ui-resizable-se").addClass("ui-icon = ui-icon-grip-diagonal-se")},_position:function(i){var = e=3Dc(window),f=3Dc(document),g=3Df.scrollTop(),d=3Df.scrollLeft(),h=3Dg;= if(c.inArray(i,["center","top","right","bottom","left"])>=3D0){i=3D[i=3D=3D= "right"||i=3D=3D"left"?i:"center",i=3D=3D"top"||i=3D=3D"bottom"?i:"middle= "]}if(i.constructor!=3DArray){i=3D["center","middle"]}if(i[0].constructor= =3D=3DNumber){d+=3Di[0]}else{switch(i[0]){case"left":d+=3D0;break;case"ri= ght":d+=3De.width()-this.uiDialog.outerWidth();break;default:case"center"= :d+=3D(e.width()-this.uiDialog.outerWidth())/2}}if(i[1].constructor=3D=3D= Number){g+=3Di[1]}else{switch(i[1]){case"top":g+=3D0;break;case"bottom":g= +=3De.height()-this.uiDialog.outerHeight();break;default:case"middle":g+=3D= (e.height()-this.uiDialog.outerHeight())/2}}g=3DMath.max(g,h);this.uiDial= og.css({top:g,left:d})},_setData:function(e,f){(b[e]&&this.uiDialog.data(= b[e],f));switch(e){case"buttons":this._createButtons(f);break;case"closeT= ext":this.uiDialogTitlebarCloseText.text(f);break;case"dialogClass":this.= uiDialog.removeClass(this.options.dialogClass).addClass(a+f);break;case"d= raggable":(f?this._makeDraggable():this.uiDialog.draggable("destroy"));br= eak;case"height":this.uiDialog.height(f);break;case"position":this._posit= ion(f);break;case"resizable":var = d=3Dthis.uiDialog,g=3Dthis.uiDialog.is(":data(resizable)");(g&&!f&&d.resi= zable("destroy"));(g&&typeof = f=3D=3D"string"&&d.resizable("option","handles",f));(g||this._makeResizab= le(f));break;case"title":c(".ui-dialog-title",this.uiDialogTitlebar).html= (f||" ");break;case"width":this.uiDialog.width(f);break}c.widget.pro= totype._setData.apply(this,arguments)},_size:function(){var = e=3Dthis.options;this.element.css({height:0,minHeight:0,width:"auto"});va= r = d=3Dthis.uiDialog.css({height:"auto",width:e.width}).height();this.elemen= t.css({minHeight:Math.max(e.minHeight-d,0),height:e.height=3D=3D"auto"?"a= uto":Math.max(e.height-d,0)})}});c.extend(c.ui.dialog,{version:"1.7.1",de= faults:{autoOpen:true,bgiframe:false,buttons:{},closeOnEscape:true,closeT= ext:"close",dialogClass:"",draggable:true,hide:null,height:"auto",maxHeig= ht:false,maxWidth:false,minHeight:150,minWidth:150,modal:false,position:"= center",resizable:true,show:null,stack:true,title:"",width:300,zIndex:100= 0},getter:"isOpen",uuid:0,maxZ:0,getTitleId:function(d){return"ui-dialog-= title-"+(d.attr("id")||++this.uuid)},overlay:function(d){this.$el=3Dc.ui.= dialog.overlay.create(d)}});c.extend(c.ui.dialog.overlay,{instances:[],ma= xZ:0,events:c.map("focus,mousedown,mouseup,keydown,keypress,click".split(= ","),function(d){return d+".dialog-overlay"}).join(" = "),create:function(e){if(this.instances.length=3D=3D=3D0){setTimeout(func= tion(){c(document).bind(c.ui.dialog.overlay.events,function(f){var = g=3Dc(f.target).parents(".ui-dialog").css("zIndex")||0;return(g>c.ui.dial= og.overlay.maxZ)})},1);c(document).bind("keydown.dialog-overlay",function= (f){(e.options.closeOnEscape&&f.keyCode&&f.keyCode=3D=3Dc.ui.keyCode.ESCA= PE&&e.close(f))});c(window).bind("resize.dialog-overlay",c.ui.dialog.over= lay.resize)}var = d=3Dc("
    ").appendTo(document.body).addClass("ui-widget-overlay"= ).css({width:this.width(),height:this.height()});(e.options.bgiframe&&c.f= n.bgiframe&&d.bgiframe());this.instances.push(d);return = d},destroy:function(d){this.instances.splice(c.inArray(this.instances,d),= 1);if(this.instances.length=3D=3D=3D0){c([document,window]).unbind(".dial= og-overlay")}d.remove()},height:function(){if(c.browser.msie&&c.browser.v= ersion<7){var = e=3DMath.max(document.documentElement.scrollHeight,document.body.scrollHe= ight);var = d=3DMath.max(document.documentElement.offsetHeight,document.body.offsetHe= ight);if(e
    ");if(!c.values){c.values=3D[this._valueMin(),t= his._valueMin()]}if(c.values.length&&c.values.length!=3D2){c.values=3D[c.= values[0],c.values[0]]}}else{this.range=3Da("
    ")}this.range.app= endTo(this.element).addClass("ui-slider-range");if(c.range=3D=3D"min"||c.= range=3D=3D"max"){this.range.addClass("ui-slider-range-"+c.range)}this.ra= nge.addClass("ui-widget-header")}if(a(".ui-slider-handle",this.element).l= ength=3D=3D0){a('    ').appendTo(this.element).addClass("ui-slider-handle")}if(= c.values&&c.values.length){while(a(".ui-slider-handle",this.element).leng= th').appendTo(this.element).addClass("ui-slider-handle")}}th= is.handles=3Da(".ui-slider-handle",this.element).addClass("ui-state-defau= lt = ui-corner-all");this.handle=3Dthis.handles.eq(0);this.handles.add(this.ra= nge).filter("a").click(function(d){d.preventDefault()}).hover(function(){= a(this).addClass("ui-state-hover")},function(){a(this).removeClass("ui-st= ate-hover")}).focus(function(){a(".ui-slider = .ui-state-focus").removeClass("ui-state-focus");a(this).addClass("ui-stat= e-focus")}).blur(function(){a(this).removeClass("ui-state-focus")});this.= handles.each(function(d){a(this).data("index.ui-slider-handle",d)});this.= handles.keydown(function(i){var f=3Dtrue;var = e=3Da(this).data("index.ui-slider-handle");if(b.options.disabled){return}= switch(i.keyCode){case a.ui.keyCode.HOME:case a.ui.keyCode.END:case = a.ui.keyCode.UP:case a.ui.keyCode.RIGHT:case a.ui.keyCode.DOWN:case = a.ui.keyCode.LEFT:f=3Dfalse;if(!b._keySliding){b._keySliding=3Dtrue;a(thi= s).addClass("ui-state-active");b._start(i,e)}break}var = g,d,h=3Db._step();if(b.options.values&&b.options.values.length){g=3Dd=3Db= .values(e)}else{g=3Dd=3Db.value()}switch(i.keyCode){case = a.ui.keyCode.HOME:d=3Db._valueMin();break;case = a.ui.keyCode.END:d=3Db._valueMax();break;case a.ui.keyCode.UP:case = a.ui.keyCode.RIGHT:if(g=3D=3Db._valueMax()){return}d=3Dg+h;break;case = a.ui.keyCode.DOWN:case = a.ui.keyCode.LEFT:if(g=3D=3Db._valueMin()){return}d=3Dg-h;break}b._slide(= i,e,d);return f}).keyup(function(e){var = d=3Da(this).data("index.ui-slider-handle");if(b._keySliding){b._stop(e,d)= ;b._change(e,d);b._keySliding=3Dfalse;a(this).removeClass("ui-state-activ= e")}});this._refreshValue()},destroy:function(){this.handles.remove();thi= s.range.remove();this.element.removeClass("ui-slider = ui-slider-horizontal ui-slider-vertical ui-slider-disabled ui-widget = ui-widget-content = ui-corner-all").removeData("slider").unbind(".slider");this._mouseDestroy= ()},_mouseCapture:function(d){var e=3Dthis.options;if(e.disabled){return = false}this.elementSize=3D{width:this.element.outerWidth(),height:this.ele= ment.outerHeight()};this.elementOffset=3Dthis.element.offset();var = h=3D{x:d.pageX,y:d.pageY};var j=3Dthis._normValueFromMouse(h);var = c=3Dthis._valueMax()-this._valueMin()+1,f;var = k=3Dthis,i;this.handles.each(function(l){var = m=3DMath.abs(j-k.values(l));if(c>m){c=3Dm;f=3Da(this);i=3Dl}});if(e.range= =3D=3Dtrue&&this.values(1)=3D=3De.min){f=3Da(this.handles[++i])}this._sta= rt(d,i);k._handleIndex=3Di;f.addClass("ui-state-active").focus();var = g=3Df.offset();var = b=3D!a(d.target).parents().andSelf().is(".ui-slider-handle");this._clickO= ffset=3Db?{left:0,top:0}:{left:d.pageX-g.left-(f.width()/2),top:d.pageY-g= .top-(f.height()/2)-(parseInt(f.css("borderTopWidth"),10)||0)-(parseInt(f= .css("borderBottomWidth"),10)||0)+(parseInt(f.css("marginTop"),10)||0)};j= =3Dthis._normValueFromMouse(h);this._slide(d,i,j);return = true},_mouseStart:function(b){return true},_mouseDrag:function(d){var = b=3D{x:d.pageX,y:d.pageY};var = c=3Dthis._normValueFromMouse(b);this._slide(d,this._handleIndex,c);return= = false},_mouseStop:function(b){this.handles.removeClass("ui-state-active")= ;this._stop(b,this._handleIndex);this._change(b,this._handleIndex);this._= handleIndex=3Dnull;this._clickOffset=3Dnull;return = false},_detectOrientation:function(){this.orientation=3Dthis.options.orie= ntation=3D=3D"vertical"?"vertical":"horizontal"},_normValueFromMouse:func= tion(d){var = c,h;if("horizontal"=3D=3Dthis.orientation){c=3Dthis.elementSize.width;h=3D= d.x-this.elementOffset.left-(this._clickOffset?this._clickOffset.left:0)}= else{c=3Dthis.elementSize.height;h=3Dd.y-this.elementOffset.top-(this._cl= ickOffset?this._clickOffset.top:0)}var = f=3D(h/c);if(f>1){f=3D1}if(f<0){f=3D0}if("vertical"=3D=3Dthis.orientation= ){f=3D1-f}var = e=3Dthis._valueMax()-this._valueMin(),i=3Df*e,b=3Di%this.options.step,g=3D= this._valueMin()+i-b;if(b>(this.options.step/2)){g+=3Dthis.options.step}r= eturn parseFloat(g.toFixed(5))},_start:function(d,c){var = b=3D{handle:this.handles[c],value:this.value()};if(this.options.values&&t= his.options.values.length){b.value=3Dthis.values(c);b.values=3Dthis.value= s()}this._trigger("start",d,b)},_slide:function(f,e,d){var = g=3Dthis.handles[e];if(this.options.values&&this.options.values.length){v= ar = b=3Dthis.values(e?0:1);if((e=3D=3D0&&d>=3Db)||(e=3D=3D1&&d<=3Db)){d=3Db}i= f(d!=3Dthis.values(e)){var c=3Dthis.values();c[e]=3Dd;var = h=3Dthis._trigger("slide",f,{handle:this.handles[e],value:d,values:c});va= r = b=3Dthis.values(e?0:1);if(h!=3D=3Dfalse){this.values(e,d,(f.type=3D=3D"mo= usedown"&&this.options.animate),true)}}}else{if(d!=3Dthis.value()){var = h=3Dthis._trigger("slide",f,{handle:this.handles[e],value:d});if(h!=3D=3D= false){this._setData("value",d,(f.type=3D=3D"mousedown"&&this.options.ani= mate))}}}},_stop:function(d,c){var = b=3D{handle:this.handles[c],value:this.value()};if(this.options.values&&t= his.options.values.length){b.value=3Dthis.values(c);b.values=3Dthis.value= s()}this._trigger("stop",d,b)},_change:function(d,c){var = b=3D{handle:this.handles[c],value:this.value()};if(this.options.values&&t= his.options.values.length){b.value=3Dthis.values(c);b.values=3Dthis.value= s()}this._trigger("change",d,b)},value:function(b){if(arguments.length){t= his._setData("value",b);this._change(null,0)}return = this._value()},values:function(b,e,c,d){if(arguments.length>1){this.optio= ns.values[b]=3De;this._refreshValue(c);if(!d){this._change(null,b)}}if(ar= guments.length){if(this.options.values&&this.options.values.length){retur= n this._values(b)}else{return this.value()}}else{return = this._values()}},_setData:function(b,d,c){a.widget.prototype._setData.app= ly(this,arguments);switch(b){case"orientation":this._detectOrientation();= this.element.removeClass("ui-slider-horizontal = ui-slider-vertical").addClass("ui-slider-"+this.orientation);this._refres= hValue(c);break;case"value":this._refreshValue(c);break}},_step:function(= ){var b=3Dthis.options.step;return b},_value:function(){var = b=3Dthis.options.value;if(bt= his._valueMax()){b=3Dthis._valueMax()}return = b},_values:function(b){if(arguments.length){var = c=3Dthis.options.values[b];if(cthis._valueMax()){c=3Dthis._valueMax()}return c}else{return = this.options.values}},_valueMin:function(){var = b=3Dthis.options.min;return b},_valueMax:function(){var = b=3Dthis.options.max;return 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ss":"removeClass"]("ui-tabs-collapsible");if(d.cookie){this._cookie(d.sel= ected,d.cookie)}for(var = g=3D0,m;(m=3Dthis.lis[g]);g++){a(m)[a.inArray(g,d.disabled)!=3D-1&&!a(m).= hasClass("ui-tabs-selected")?"addClass":"removeClass"]("ui-state-disabled= ")}if(d.cache=3D=3D=3Dfalse){this.anchors.removeData("cache.tabs")}this.l= is.add(this.anchors).unbind(".tabs");if(d.event!=3D"mouseover"){var = f=3Dfunction(o,i){if(i.is(":not(.ui-state-disabled)")){i.addClass("ui-sta= te-"+o)}};var = j=3Dfunction(o,i){i.removeClass("ui-state-"+o)};this.lis.bind("mouseover.= tabs",function(){f("hover",a(this))});this.lis.bind("mouseout.tabs",funct= ion(){j("hover",a(this))});this.anchors.bind("focus.tabs",function(){f("f= ocus",a(this).closest("li"))});this.anchors.bind("blur.tabs",function(){j= ("focus",a(this).closest("li"))})}var = b,h;if(d.fx){if(a.isArray(d.fx)){b=3Dd.fx[0];h=3Dd.fx[1]}else{b=3Dh=3Dd.f= x}}function = e(i,o){i.css({display:""});if(a.browser.msie&&o.opacity){i[0].style.remov= 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e)"),q=3Da(p._sanitizeSelector(this.hash));if((r.hasClass("ui-tabs-select= ed")&&!d.collapsible)||r.hasClass("ui-state-disabled")||r.hasClass("ui-st= ate-processing")||p._trigger("select",null,p._ui(this,q[0]))=3D=3D=3Dfals= e){this.blur();return = false}d.selected=3Dp.anchors.index(this);p.abort();if(d.collapsible){if(r= .hasClass("ui-tabs-selected")){d.selected=3D-1;if(d.cookie){p._cookie(d.s= elected,d.cookie)}p.element.queue("tabs",function(){l(o,i)}).dequeue("tab= s");this.blur();return = false}else{if(!i.length){if(d.cookie){p._cookie(d.selected,d.cookie)}p.el= ement.queue("tabs",function(){k(o,q)});p.load(p.anchors.index(this));this= .blur();return = false}}}if(d.cookie){p._cookie(d.selected,d.cookie)}if(q.length){if(i.len= gth){p.element.queue("tabs",function(){l(o,i)})}p.element.queue("tabs",fu= nction(){k(o,q)});p.load(p.anchors.index(this))}else{throw"jQuery UI = Tabs: Mismatching fragment = identifier."}if(a.browser.msie){this.blur()}});this.anchors.bind("click.t= abs",function(){return false})},destroy:function(){var = b=3Dthis.options;this.abort();this.element.unbind(".tabs").removeClass("u= i-tabs ui-widget ui-widget-content ui-corner-all = ui-tabs-collapsible").removeData("tabs");this.list.removeClass("ui-tabs-n= av ui-helper-reset ui-helper-clearfix ui-widget-header = ui-corner-all");this.anchors.each(function(){var = c=3Da.data(this,"href.tabs");if(c){this.href=3Dc}var = d=3Da(this).unbind(".tabs");a.each(["href","load","cache"],function(e,f){= d.removeData(f+".tabs")})});this.lis.unbind(".tabs").add(this.panels).eac= h(function(){if(a.data(this,"destroy.tabs")){a(this).remove()}else{a(this= ).removeClass(["ui-state-default","ui-corner-top","ui-tabs-selected","ui-= state-active","ui-state-hover","ui-state-focus","ui-state-disabled","ui-t= abs-panel","ui-widget-content","ui-corner-bottom","ui-tabs-hide"].join(" = "))}});if(b.cookie){this._cookie(null,b.cookie)}},add:function(e,d,c){if(= c=3D=3D=3Dundefined){c=3Dthis.anchors.length}var = b=3Dthis,g=3Dthis.options,i=3Da(g.tabTemplate.replace(/#\{href\}/g,e).rep= lace(/#\{label\}/g,d)),h=3D!e.indexOf("#")?e.replace("#",""):this._tabId(= a("a",i)[0]);i.addClass("ui-state-default = ui-corner-top").data("destroy.tabs",true);var = f=3Da("#"+h);if(!f.length){f=3Da(g.panelTemplate).attr("id",h).data("dest= roy.tabs",true)}f.addClass("ui-tabs-panel ui-widget-content = ui-corner-bottom = ui-tabs-hide");if(c>=3Dthis.lis.length){i.appendTo(this.list);f.appendTo(= this.list[0].parentNode)}else{i.insertBefore(this.lis[c]);f.insertBefore(= this.panels[c])}g.disabled=3Da.map(g.disabled,function(k,j){return = k>=3Dc?++k:k});this._tabify();if(this.anchors.length=3D=3D1){i.addClass("= ui-tabs-selected = ui-state-active");f.removeClass("ui-tabs-hide");this.element.queue("tabs"= ,function(){b._trigger("show",null,b._ui(b.anchors[0],b.panels[0]))});thi= s.load(0)}this._trigger("add",null,this._ui(this.anchors[c],this.panels[c= ]))},remove:function(b){var = d=3Dthis.options,e=3Dthis.lis.eq(b).remove(),c=3Dthis.panels.eq(b).remove= ();if(e.hasClass("ui-tabs-selected")&&this.anchors.length>1){this.select(= b+(b+1=3Db?--g:g});this._tabify();this._trigger("remove",null,this._ui(e.find= ("a")[0],c[0]))},enable:function(b){var = c=3Dthis.options;if(a.inArray(b,c.disabled)=3D=3D-1){return}this.lis.eq(b= ).removeClass("ui-state-disabled");c.disabled=3Da.grep(c.disabled,functio= n(e,d){return = e!=3Db});this._trigger("enable",null,this._ui(this.anchors[b],this.panels= [b]))},disable:function(c){var = b=3Dthis,d=3Dthis.options;if(c!=3Dd.selected){this.lis.eq(c).addClass("ui= -state-disabled");d.disabled.push(c);d.disabled.sort();this._trigger("dis= able",null,this._ui(this.anchors[c],this.panels[c]))}},select:function(b)= {if(typeof = b=3D=3D"string"){b=3Dthis.anchors.index(this.anchors.filter("[href$=3D"+b= +"]"))}else{if(b=3D=3D=3Dnull){b=3D-1}}if(b=3D=3D-1&&this.options.collaps= ible){b=3Dthis.options.selected}this.anchors.eq(b).trigger(this.options.e= vent+".tabs")},load:function(e){var = c=3Dthis,g=3Dthis.options,b=3Dthis.anchors.eq(e)[0],d=3Da.data(b,"load.ta= bs");this.abort();if(!d||this.element.queue("tabs").length!=3D=3D0&&a.dat= a(b,"cache.tabs")){this.element.dequeue("tabs");return}this.lis.eq(e).add= Class("ui-state-processing");if(g.spinner){var = f=3Da("span",b);f.data("label.tabs",f.html()).html(g.spinner)}this.xhr=3D= a.ajax(a.extend({},g.ajaxOptions,{url:d,success:function(i,h){a(c._saniti= zeSelector(b.hash)).html(i);c._cleanup();if(g.cache){a.data(b,"cache.tabs= ",true)}c._trigger("load",null,c._ui(c.anchors[e],c.panels[e]));try{g.aja= xOptions.success(i,h)}catch(j){}c.element.dequeue("tabs")}}))},abort:func= tion(){this.element.queue([]);this.panels.stop(false,true);if(this.xhr){t= his.xhr.abort();delete = this.xhr}this._cleanup()},url:function(c,b){this.anchors.eq(c).removeData= ("cache.tabs").data("load.tabs",b)},length:function(){return = this.anchors.length}});a.extend(a.ui.tabs,{version:"1.7.1",getter:"length= ",defaults:{ajaxOptions:null,cache:false,cookie:null,collapsible:false,di= sabled:[],event:"click",fx:null,idPrefix:"ui-tabs-",panelTemplate:"
    <= /div>",spinner:"Loading…",tabTemplate:'
  • #{label}
    • '}});a.extend(a.ui.tabs.pr= ototype,{rotation:null,rotate:function(d,f){var = b=3Dthis,g=3Dthis.options;var = c=3Db._rotate||(b._rotate=3Dfunction(h){clearTimeout(b.rotation);b.rotati= on=3DsetTimeout(function(){var = i=3Dg.selected;b.select(++i
    ')}$.extend(Datepicker.prototype,{mark= erClassName:"hasDatepicker",log:function(){if(this.debug){console.log.app= ly("",arguments)}},setDefaults:function(settings){extendRemove(this._defa= ults,settings||{});return = this},_attachDatepicker:function(target,settings){var = inlineSettings=3Dnull;for(var attrName in this._defaults){var = attrValue=3Dtarget.getAttribute("date:"+attrName);if(attrValue){inlineSet= tings=3DinlineSettings||{};try{inlineSettings[attrName]=3Deval(attrValue)= }catch(err){inlineSettings[attrName]=3DattrValue}}}var = nodeName=3Dtarget.nodeName.toLowerCase();var = inline=3D(nodeName=3D=3D"div"||nodeName=3D=3D"span");if(!target.id){targe= t.id=3D"dp"+(++this.uuid)}var = inst=3Dthis._newInst($(target),inline);inst.settings=3D$.extend({},settin= gs||{},inlineSettings||{});if(nodeName=3D=3D"input"){this._connectDatepic= ker(target,inst)}else{if(inline){this._inlineDatepicker(target,inst)}}},_= newInst:function(target,inline){var = id=3Dtarget[0].id.replace(/([:\[\]\.])/g,"\\\\$1");return{id:id,input:tar= get,selectedDay:0,selectedMonth:0,selectedYear:0,drawMonth:0,drawYear:0,i= nline:inline,dpDiv:(!inline?this.dpDiv:$('
    '))}},_connectDatepicker:function(target,inst){var = input=3D$(target);inst.trigger=3D$([]);if(input.hasClass(this.markerClass= Name)){return}var appendText=3Dthis._get(inst,"appendText");var = isRTL=3Dthis._get(inst,"isRTL");if(appendText){input[isRTL?"before":"afte= r"](''+appendText+"")}var = showOn=3Dthis._get(inst,"showOn");if(showOn=3D=3D"focus"||showOn=3D=3D"bo= th"){input.focus(this._showDatepicker)}if(showOn=3D=3D"button"||showOn=3D= =3D"both"){var buttonText=3Dthis._get(inst,"buttonText");var = buttonImage=3Dthis._get(inst,"buttonImage");inst.trigger=3D$(this._get(in= st,"buttonImageOnly")?$("").addClass(this._triggerClass).attr({src:= buttonImage,alt:buttonText,title:buttonText}):$('').addClass(this._triggerClass).html(buttonImage= =3D=3D""?buttonText:$("").attr({src:buttonImage,alt:buttonText,titl= e:buttonText})));input[isRTL?"before":"after"](inst.trigger);inst.trigger= .click(function(){if($.datepicker._datepickerShowing&&$.datepicker._lastI= nput=3D=3Dtarget){$.datepicker._hideDatepicker()}else{$.datepicker._showD= atepicker(target)}return = false})}input.addClass(this.markerClassName).keydown(this._doKeyDown).key= press(this._doKeyPress).bind("setData.datepicker",function(event,key,valu= e){inst.settings[key]=3Dvalue}).bind("getData.datepicker",function(event,= key){return = this._get(inst,key)});$.data(target,PROP_NAME,inst)},_inlineDatepicker:fu= nction(target,inst){var = divSpan=3D$(target);if(divSpan.hasClass(this.markerClassName)){return}div= Span.addClass(this.markerClassName).append(inst.dpDiv).bind("setData.date= picker",function(event,key,value){inst.settings[key]=3Dvalue}).bind("getD= ata.datepicker",function(event,key){return = this._get(inst,key)});$.data(target,PROP_NAME,inst);this._setDate(inst,th= is._getDefaultDate(inst));this._updateDatepicker(inst);this._updateAltern= ate(inst)},_dialogDatepicker:function(input,dateText,onSelect,settings,po= s){var inst=3Dthis._dialogInst;if(!inst){var = id=3D"dp"+(++this.uuid);this._dialogInput=3D$('');this._dialogInput.keydown(this._doKeyDown);$("body").append(= this._dialogInput);inst=3Dthis._dialogInst=3Dthis._newInst(this._dialogIn= put,false);inst.settings=3D{};$.data(this._dialogInput[0],PROP_NAME,inst)= }extendRemove(inst.settings,settings||{});this._dialogInput.val(dateText)= ;this._pos=3D(pos?(pos.length?pos:[pos.pageX,pos.pageY]):null);if(!this._= pos){var = browserWidth=3Dwindow.innerWidth||document.documentElement.clientWidth||d= ocument.body.clientWidth;var = browserHeight=3Dwindow.innerHeight||document.documentElement.clientHeight= ||document.body.clientHeight;var = scrollX=3Ddocument.documentElement.scrollLeft||document.body.scrollLeft;v= ar = scrollY=3Ddocument.documentElement.scrollTop||document.body.scrollTop;thi= s._pos=3D[(browserWidth/2)-100+scrollX,(browserHeight/2)-150+scrollY]}thi= s._dialogInput.css("left",this._pos[0]+"px").css("top",this._pos[1]+"px")= ;inst.settings.onSelect=3DonSelect;this._inDialog=3Dtrue;this.dpDiv.addCl= ass(this._dialogClass);this._showDatepicker(this._dialogInput[0]);if($.bl= ockUI){$.blockUI(this.dpDiv)}$.data(this._dialogInput[0],PROP_NAME,inst);= return this},_destroyDatepicker:function(target){var = $target=3D$(target);var = inst=3D$.data(target,PROP_NAME);if(!$target.hasClass(this.markerClassName= )){return}var = nodeName=3Dtarget.nodeName.toLowerCase();$.removeData(target,PROP_NAME);i= f(nodeName=3D=3D"input"){inst.trigger.remove();$target.siblings("."+this.= _appendClass).remove().end().removeClass(this.markerClassName).unbind("fo= cus",this._showDatepicker).unbind("keydown",this._doKeyDown).unbind("keyp= ress",this._doKeyPress)}else{if(nodeName=3D=3D"div"||nodeName=3D=3D"span"= ){$target.removeClass(this.markerClassName).empty()}}},_enableDatepicker:= function(target){var $target=3D$(target);var = inst=3D$.data(target,PROP_NAME);if(!$target.hasClass(this.markerClassName= )){return}var = nodeName=3Dtarget.nodeName.toLowerCase();if(nodeName=3D=3D"input"){target= .disabled=3Dfalse;inst.trigger.filter("button").each(function(){this.disa= bled=3Dfalse}).end().filter("img").css({opacity:"1.0",cursor:""})}else{if= (nodeName=3D=3D"div"||nodeName=3D=3D"span"){var = inline=3D$target.children("."+this._inlineClass);inline.children().remove= Class("ui-state-disabled")}}this._disabledInputs=3D$.map(this._disabledIn= puts,function(value){return(value=3D=3Dtarget?null:value)})},_disableDate= picker:function(target){var $target=3D$(target);var = inst=3D$.data(target,PROP_NAME);if(!$target.hasClass(this.markerClassName= )){return}var = nodeName=3Dtarget.nodeName.toLowerCase();if(nodeName=3D=3D"input"){target= .disabled=3Dtrue;inst.trigger.filter("button").each(function(){this.disab= led=3Dtrue}).end().filter("img").css({opacity:"0.5",cursor:"default"})}el= se{if(nodeName=3D=3D"div"||nodeName=3D=3D"span"){var = inline=3D$target.children("."+this._inlineClass);inline.children().addCla= ss("ui-state-disabled")}}this._disabledInputs=3D$.map(this._disabledInput= s,function(value){return(value=3D=3Dtarget?null:value)});this._disabledIn= puts[this._disabledInputs.length]=3Dtarget},_isDisabledDatepicker:functio= n(target){if(!target){return false}for(var = i=3D0;i1){inst.dpDiv.addClass("ui-datepicker-multi-"+cols).cs= s("width",(width*cols)+"em")}else{inst.dpDiv.removeClass("ui-datepicker-m= ulti-2 ui-datepicker-multi-3 = ui-datepicker-multi-4").width("")}inst.dpDiv[(numMonths[0]!=3D1||numMonth= s[1]!=3D1?"add":"remove")+"Class"]("ui-datepicker-multi");inst.dpDiv[(thi= s._get(inst,"isRTL")?"add":"remove")+"Class"]("ui-datepicker-rtl");if(ins= t.input&&inst.input[0].type!=3D"hidden"&&inst=3D=3D$.datepicker._curInst)= {$(inst.input[0]).focus()}},_checkOffset:function(inst,offset,isFixed){va= r dpWidth=3Dinst.dpDiv.outerWidth();var = dpHeight=3Dinst.dpDiv.outerHeight();var = inputWidth=3Dinst.input?inst.input.outerWidth():0;var = inputHeight=3Dinst.input?inst.input.outerHeight():0;var = viewWidth=3D(window.innerWidth||document.documentElement.clientWidth||doc= ument.body.clientWidth)+$(document).scrollLeft();var = viewHeight=3D(window.innerHeight||document.documentElement.clientHeight||= document.body.clientHeight)+$(document).scrollTop();offset.left-=3D(this.= _get(inst,"isRTL")?(dpWidth-inputWidth):0);offset.left-=3D(isFixed&&offse= t.left=3D=3Dinst.input.offset().left)?$(document).scrollLeft():0;offset.t= op-=3D(isFixed&&offset.top=3D=3D(inst.input.offset().top+inputHeight))?$(= document).scrollTop():0;offset.left-=3D(offset.left+dpWidth>viewWidth&&vi= ewWidth>dpWidth)?Math.abs(offset.left+dpWidth-viewWidth):0;offset.top-=3D= (offset.top+dpHeight>viewHeight&&viewHeight>dpHeight)?Math.abs(offset.top= +dpHeight+inputHeight*2-viewHeight):0;return = offset},_findPos:function(obj){while(obj&&(obj.type=3D=3D"hidden"||obj.no= deType!=3D1)){obj=3Dobj.nextSibling}var = position=3D$(obj).offset();return[position.left,position.top]},_hideDatep= icker:function(input,duration){var = inst=3Dthis._curInst;if(!inst||(input&&inst!=3D$.data(input,PROP_NAME))){= return}if(inst.stayOpen){this._selectDate("#"+inst.id,this._formatDate(in= st,inst.currentDay,inst.currentMonth,inst.currentYear))}inst.stayOpen=3Df= alse;if(this._datepickerShowing){duration=3D(duration!=3Dnull?duration:th= is._get(inst,"duration"));var showAnim=3Dthis._get(inst,"showAnim");var = postProcess=3Dfunction(){$.datepicker._tidyDialog(inst)};if(duration!=3D"= "&&$.effects&&$.effects[showAnim]){inst.dpDiv.hide(showAnim,$.datepicker.= _get(inst,"showOptions"),duration,postProcess)}else{inst.dpDiv[(duration=3D= =3D""?"hide":(showAnim=3D=3D"slideDown"?"slideUp":(showAnim=3D=3D"fadeIn"= ?"fadeOut":"hide")))](duration,postProcess)}if(duration=3D=3D""){this._ti= dyDialog(inst)}var = onClose=3Dthis._get(inst,"onClose");if(onClose){onClose.apply((inst.input= ?inst.input[0]:null),[(inst.input?inst.input.val():""),inst])}this._datep= ickerShowing=3Dfalse;this._lastInput=3Dnull;if(this._inDialog){this._dial= ogInput.css({position:"absolute",left:"0",top:"-100px"});if($.blockUI){$.= unblockUI();$("body").append(this.dpDiv)}}this._inDialog=3Dfalse}this._cu= rInst=3Dnull},_tidyDialog:function(inst){inst.dpDiv.removeClass(this._dia= logClass).unbind(".ui-datepicker-calendar")},_checkExternalClick:function= (event){if(!$.datepicker._curInst){return}var = $target=3D$(event.target);if(($target.parents("#"+$.datepicker._mainDivId= ).length=3D=3D0)&&!$target.hasClass($.datepicker.markerClassName)&&!$targ= et.hasClass($.datepicker._triggerClass)&&$.datepicker._datepickerShowing&= &!($.datepicker._inDialog&&$.blockUI)){$.datepicker._hideDatepicker(null,= "")}},_adjustDate:function(id,offset,period){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);if(this._isDisabledDatepicker(target[0]))= {return}this._adjustInstDate(inst,offset+(period=3D=3D"M"?this._get(inst,= "showCurrentAtPos"):0),period);this._updateDatepicker(inst)},_gotoToday:f= unction(id){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);if(this._get(inst,"gotoCurrent")&&inst.cu= rrentDay){inst.selectedDay=3Dinst.currentDay;inst.drawMonth=3Dinst.select= edMonth=3Dinst.currentMonth;inst.drawYear=3Dinst.selectedYear=3Dinst.curr= entYear}else{var date=3Dnew = Date();inst.selectedDay=3Ddate.getDate();inst.drawMonth=3Dinst.selectedMo= nth=3Ddate.getMonth();inst.drawYear=3Dinst.selectedYear=3Ddate.getFullYea= r()}this._notifyChange(inst);this._adjustDate(target)},_selectMonthYear:f= unction(id,select,period){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);inst._selectingMonthYear=3Dfalse;inst["se= lected"+(period=3D=3D"M"?"Month":"Year")]=3Dinst["draw"+(period=3D=3D"M"?= "Month":"Year")]=3DparseInt(select.options[select.selectedIndex].value,10= );this._notifyChange(inst);this._adjustDate(target)},_clickMonthYear:func= tion(id){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);if(inst.input&&inst._selectingMonthYear&&= !$.browser.msie){inst.input[0].focus()}inst._selectingMonthYear=3D!inst._= selectingMonthYear},_selectDay:function(id,month,year,td){var = target=3D$(id);if($(td).hasClass(this._unselectableClass)||this._isDisabl= edDatepicker(target[0])){return}var = inst=3Dthis._getInst(target[0]);inst.selectedDay=3Dinst.currentDay=3D$("a= ",td).html();inst.selectedMonth=3Dinst.currentMonth=3Dmonth;inst.selected= Year=3Dinst.currentYear=3Dyear;if(inst.stayOpen){inst.endDay=3Dinst.endMo= nth=3Dinst.endYear=3Dnull}this._selectDate(id,this._formatDate(inst,inst.= currentDay,inst.currentMonth,inst.currentYear));if(inst.stayOpen){inst.ra= ngeStart=3Dthis._daylightSavingAdjust(new = Date(inst.currentYear,inst.currentMonth,inst.currentDay));this._updateDat= epicker(inst)}},_clearDate:function(id){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);inst.stayOpen=3Dfalse;inst.endDay=3Dinst.= endMonth=3Dinst.endYear=3Dinst.rangeStart=3Dnull;this._selectDate(target,= "")},_selectDate:function(id,dateStr){var target=3D$(id);var = inst=3Dthis._getInst(target[0]);dateStr=3D(dateStr!=3Dnull?dateStr:this._= formatDate(inst));if(inst.input){inst.input.val(dateStr)}this._updateAlte= rnate(inst);var = onSelect=3Dthis._get(inst,"onSelect");if(onSelect){onSelect.apply((inst.i= nput?inst.input[0]:null),[dateStr,inst])}else{if(inst.input){inst.input.t= rigger("change")}}if(inst.inline){this._updateDatepicker(inst)}else{if(!i= nst.stayOpen){this._hideDatepicker(null,this._get(inst,"duration"));this.= _lastInput=3Dinst.input[0];if(typeof(inst.input[0])!=3D"object"){inst.inp= ut[0].focus()}this._lastInput=3Dnull}}},_updateAlternate:function(inst){v= ar altField=3Dthis._get(inst,"altField");if(altField){var = altFormat=3Dthis._get(inst,"altFormat")||this._get(inst,"dateFormat");var= = date=3Dthis._getDate(inst);dateStr=3Dthis.formatDate(altFormat,date,this.= _getFormatConfig(inst));$(altField).each(function(){$(this).val(dateStr)}= )}},noWeekends:function(date){var = day=3Ddate.getDay();return[(day>0&&day<6),""]},iso8601Week:function(date)= {var checkDate=3Dnew = Date(date.getFullYear(),date.getMonth(),date.getDate());var = firstMon=3Dnew Date(checkDate.getFullYear(),1-1,4);var = firstDay=3DfirstMon.getDay()||7;firstMon.setDate(firstMon.getDate()+1-fir= stDay);if(firstDay<4&&checkDatenew = Date(checkDate.getFullYear(),12-1,28)){firstDay=3Dnew = Date(checkDate.getFullYear()+1,1-1,4).getDay()||7;if(firstDay>4&&(checkDa= te.getDay()||7)0&&iValue=3D"0"&&v= alue.charAt(iValue)<=3D"9"){num=3Dnum*10+parseInt(value.charAt(iValue++),= 10);size--}if(size=3D=3DorigSize){throw"Missing number at position = "+iValue}return num};var = getName=3Dfunction(match,shortNames,longNames){var = names=3D(lookAhead(match)?longNames:shortNames);var size=3D0;for(var = j=3D0;j0&&iValue-1){mon= th=3D1;day=3Ddoy;do{var = dim=3Dthis._getDaysInMonth(year,month-1);if(day<=3Ddim){break}month++;day= -=3Ddim}while(true)}var date=3Dthis._daylightSavingAdjust(new = Date(year,month-1,day));if(date.getFullYear()!=3Dyear||date.getMonth()+1!= =3Dmonth||date.getDate()!=3Dday){throw"Invalid date"}return = date},ATOM:"yy-mm-dd",COOKIE:"D, dd M = yy",ISO_8601:"yy-mm-dd",RFC_822:"D, d M y",RFC_850:"DD, = dd-M-y",RFC_1036:"D, d M y",RFC_1123:"D, d M yy",RFC_2822:"D, d M = yy",RSS:"D, d M = y",TIMESTAMP:"@",W3C:"yy-mm-dd",formatDate:function(format,date,settings)= {if(!date){return""}var = dayNamesShort=3D(settings?settings.dayNamesShort:null)||this._defaults.da= yNamesShort;var = dayNames=3D(settings?settings.dayNames:null)||this._defaults.dayNames;var= = monthNamesShort=3D(settings?settings.monthNamesShort:null)||this._default= s.monthNamesShort;var = monthNames=3D(settings?settings.monthNames:null)||this._defaults.monthNam= es;var lookAhead=3Dfunction(match){var = matches=3D(iFormat+1=3D0;m--){doy+=3Dthis._getDaysInMonth(date.getFul= lYear(),m)}output+=3DformatNumber("o",doy,3);break;case"m":output+=3Dform= atNumber("m",date.getMonth()+1,2);break;case"M":output+=3DformatName("M",= date.getMonth(),monthNamesShort,monthNames);break;case"y":output+=3D(look= Ahead("y")?date.getFullYear():(date.getYear()%100<10?"0":"")+date.getYear= ()%100);break;case"@":output+=3Ddate.getTime();break;case"'":if(lookAhead= ("'")){output+=3D"'"}else{literal=3Dtrue}break;default:output+=3Dformat.c= harAt(iFormat)}}}}return output},_possibleChars:function(format){var = chars=3D"";var literal=3Dfalse;for(var = iFormat=3D0;iFormatmaxDate?maxDate:date);return = date},_determineDate:function(date,defaultDate){var = offsetNumeric=3Dfunction(offset){var date=3Dnew = Date();date.setDate(date.getDate()+offset);return date};var = offsetString=3Dfunction(offset,getDaysInMonth){var date=3Dnew Date();var = year=3Ddate.getFullYear();var month=3Ddate.getMonth();var = day=3Ddate.getDate();var = pattern=3D/([+-]?[0-9]+)\s*(d|D|w|W|m|M|y|Y)?/g;var = matches=3Dpattern.exec(offset);while(matches){switch(matches[2]||"d"){cas= e"d":case"D":day+=3DparseInt(matches[1],10);break;case"w":case"W":day+=3D= parseInt(matches[1],10)*7;break;case"m":case"M":month+=3DparseInt(matches= [1],10);day=3DMath.min(day,getDaysInMonth(year,month));break;case"y":case= "Y":year+=3DparseInt(matches[1],10);day=3DMath.min(day,getDaysInMonth(yea= r,month));break}matches=3Dpattern.exec(offset)}return new = Date(year,month,day)};date=3D(date=3D=3Dnull?defaultDate:(typeof = date=3D=3D"string"?offsetString(date,this._getDaysInMonth):(typeof = date=3D=3D"number"?(isNaN(date)?defaultDate:offsetNumeric(date)):date)));= date=3D(date&&date.toString()=3D=3D"Invalid = Date"?defaultDate:date);if(date){date.setHours(0);date.setMinutes(0);date= .setSeconds(0);date.setMilliseconds(0)}return = this._daylightSavingAdjust(date)},_daylightSavingAdjust:function(date){if= (!date){return = null}date.setHours(date.getHours()>12?date.getHours()+2:0);return = date},_setDate:function(inst,date,endDate){var clear=3D!(date);var = origMonth=3Dinst.selectedMonth;var = origYear=3Dinst.selectedYear;date=3Dthis._determineDate(date,new = Date());inst.selectedDay=3Dinst.currentDay=3Ddate.getDate();inst.drawMont= h=3Dinst.selectedMonth=3Dinst.currentMonth=3Ddate.getMonth();inst.drawYea= r=3Dinst.selectedYear=3Dinst.currentYear=3Ddate.getFullYear();if(origMont= h!=3Dinst.selectedMonth||origYear!=3Dinst.selectedYear){this._notifyChang= e(inst)}this._adjustInstDate(inst);if(inst.input){inst.input.val(clear?""= :this._formatDate(inst))}},_getDate:function(inst){var = startDate=3D(!inst.currentYear||(inst.input&&inst.input.val()=3D=3D"")?nu= ll:this._daylightSavingAdjust(new = Date(inst.currentYear,inst.currentMonth,inst.currentDay)));return = startDate},_generateHTML:function(inst){var today=3Dnew = Date();today=3Dthis._daylightSavingAdjust(new = Date(today.getFullYear(),today.getMonth(),today.getDate()));var = isRTL=3Dthis._get(inst,"isRTL");var = showButtonPanel=3Dthis._get(inst,"showButtonPanel");var = hideIfNoPrevNext=3Dthis._get(inst,"hideIfNoPrevNext");var = navigationAsDateFormat=3Dthis._get(inst,"navigationAsDateFormat");var = numMonths=3Dthis._getNumberOfMonths(inst);var = showCurrentAtPos=3Dthis._get(inst,"showCurrentAtPos");var = stepMonths=3Dthis._get(inst,"stepMonths");var = stepBigMonths=3Dthis._get(inst,"stepBigMonths");var = isMultiMonth=3D(numMonths[0]!=3D1||numMonths[1]!=3D1);var = currentDate=3Dthis._daylightSavingAdjust((!inst.currentDay?new = Date(9999,9,9):new = Date(inst.currentYear,inst.currentMonth,inst.currentDay)));var = minDate=3Dthis._getMinMaxDate(inst,"min",true);var = maxDate=3Dthis._getMinMaxDate(inst,"max");var = drawMonth=3Dinst.drawMonth-showCurrentAtPos;var = drawYear=3Dinst.drawYear;if(drawMonth<0){drawMonth+=3D12;drawYear--}if(ma= xDate){var maxDraw=3Dthis._daylightSavingAdjust(new = Date(maxDate.getFullYear(),maxDate.getMonth()-numMonths[1]+1,maxDate.getD= ate()));maxDraw=3D(minDate&&maxDrawmaxDraw){drawMonth--;if(drawMonth<0){drawMont= h=3D11;drawYear--}}}inst.drawMonth=3DdrawMonth;inst.drawYear=3DdrawYear;v= ar = prevText=3Dthis._get(inst,"prevText");prevText=3D(!navigationAsDateFormat= ?prevText:this.formatDate(prevText,this._daylightSavingAdjust(new = Date(drawYear,drawMonth-stepMonths,1)),this._getFormatConfig(inst)));var = prev=3D(this._canAdjustMonth(inst,-1,drawYear,drawMonth)?''+prevText+"":(hi= deIfNoPrevNext?"":''+prevText+""));v= ar = nextText=3Dthis._get(inst,"nextText");nextText=3D(!navigationAsDateFormat= ?nextText:this.formatDate(nextText,this._daylightSavingAdjust(new = Date(drawYear,drawMonth+stepMonths,1)),this._getFormatConfig(inst)));var = next=3D(this._canAdjustMonth(inst,+1,drawYear,drawMonth)?''+nextText+"":(hi= deIfNoPrevNext?"":''+nextText+""));v= ar currentText=3Dthis._get(inst,"currentText");var = gotoDate=3D(this._get(inst,"gotoCurrent")&&inst.currentDay?currentDate:to= day);currentText=3D(!navigationAsDateFormat?currentText:this.formatDate(c= urrentText,gotoDate,this._getFormatConfig(inst)));var = controls=3D(!inst.inline?'":"");var buttonPanel=3D(showButtonPanel)?'
    '+(isRTL?controls:"")+(this._isInRange(inst,gotoDate)?= '":"")+(isRTL?"":controls)+"
    ":"";var = firstDay=3DparseInt(this._get(inst,"firstDay"),10);firstDay=3D(isNaN(firs= tDay)?0:firstDay);var dayNames=3Dthis._get(inst,"dayNames");var = dayNamesShort=3Dthis._get(inst,"dayNamesShort");var = dayNamesMin=3Dthis._get(inst,"dayNamesMin");var = monthNames=3Dthis._get(inst,"monthNames");var = monthNamesShort=3Dthis._get(inst,"monthNamesShort");var = beforeShowDay=3Dthis._get(inst,"beforeShowDay");var = showOtherMonths=3Dthis._get(inst,"showOtherMonths");var = calculateWeek=3Dthis._get(inst,"calculateWeek")||this.iso8601Week;var = endDate=3Dinst.endDay?this._daylightSavingAdjust(new = Date(inst.endYear,inst.endMonth,inst.endDay)):currentDate;var = defaultDate=3Dthis._getDefaultDate(inst);var html=3D"";for(var = row=3D0;row'}calender+=3D'
    '+(/all|left/.test(cornerClass)&&row=3D= =3D0?(isRTL?next:prev):"")+(/all|right/.test(cornerClass)&&row=3D=3D0?(is= RTL?prev:next):"")+this._generateMonthYearHeader(inst,drawMonth,drawYear,= minDate,maxDate,selectedDate,row>0||col>0,monthNames,monthNamesShort)+'';var = thead=3D"";for(var dow=3D0;dow<7;dow++){var = day=3D(dow+firstDay)%7;thead+=3D"=3D5?' = class=3D"ui-datepicker-week-end"':"")+'>'+dayNamesMin[day]+""}calender+=3D= thead+"";var = daysInMonth=3Dthis._getDaysInMonth(drawYear,drawMonth);if(drawYear=3D=3Di= nst.selectedYear&&drawMonth=3D=3Dinst.selectedMonth){inst.selectedDay=3DM= ath.min(inst.selectedDay,daysInMonth)}var = leadDays=3D(this._getFirstDayOfMonth(drawYear,drawMonth)-firstDay+7)%7;va= r numRows=3D(isMultiMonth?6:Math.ceil((leadDays+daysInMonth)/7));var = printDate=3Dthis._daylightSavingAdjust(new = Date(drawYear,drawMonth,1-leadDays));for(var = dRow=3D0;dRow";var tbody=3D"";for(var = dow=3D0;dow<7;dow++){var = daySettings=3D(beforeShowDay?beforeShowDay.apply((inst.input?inst.input[0= ]:null),[printDate]):[true,""]);var = otherMonth=3D(printDate.getMonth()!=3DdrawMonth);var = unselectable=3DotherMonth||!daySettings[0]||(minDate&&printDatemaxDate);tbody+=3D'";printDate.setDate(print= Date.getDate()+1);printDate=3Dthis._daylightSavingAdjust(printDate)}calen= der+=3Dtbody+""}drawMonth++;if(drawMonth>11){drawMonth=3D0;drawYear+= +}calender+=3D"
    =3D5?" = ui-datepicker-week-end":"")+(otherMonth?" = ui-datepicker-other-month":"")+((printDate.getTime()=3D=3DselectedDate.ge= tTime()&&drawMonth=3D=3Dinst.selectedMonth&&inst._keyEvent)||(defaultDate= .getTime()=3D=3DprintDate.getTime()&&defaultDate.getTime()=3D=3DselectedD= ate.getTime())?" "+this._dayOverClass:"")+(unselectable?" = "+this._unselectableClass+" = ui-state-disabled":"")+(otherMonth&&!showOtherMonths?"":" = "+daySettings[1]+(printDate.getTime()>=3DcurrentDate.getTime()&&printDate= .getTime()<=3DendDate.getTime()?" = "+this._currentClass:"")+(printDate.getTime()=3D=3Dtoday.getTime()?" = ui-datepicker-today":""))+'"'+((!otherMonth||showOtherMonths)&&daySetting= s[2]?' title=3D"'+daySettings[2]+'"':"")+(unselectable?"":" = onclick=3D\"DP_jQuery.datepicker._selectDay('#"+inst.id+"',"+drawMonth+",= "+drawYear+', this);return = false;"')+">"+(otherMonth?(showOtherMonths?printDate.getDate():" "):= (unselectable?''+printDate.getDate()+"":'=3DcurrentDate.getTime()&&pr= intDate.getTime()<=3DendDate.getTime()?" ui-state-active":"")+'" = href=3D"#">'+printDate.getDate()+""))+"
    "+(isMultiMonth?"
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"show" : "hide" ](); if(callback) callback.apply(this, arguments); }); }, heightHide: function(animated, callback) { if (animated) { this.animate({ height: "hide" }, animated, callback); } else { this.hide(); if (callback) this.each(callback); =09 } }, prepareBranches: function(settings) { if (!settings.prerendered) { // mark last tree items this.filter(":last-child:not(ul)").addClass(CLASSES.last); // collapse whole tree, or only those marked as closed, anyway = except those marked as open this.filter((settings.collapsed ? "" : "." + CLASSES.closed) + = ":not(." + CLASSES.open + ")").find(">ul").hide(); } // return all items with sublists return this.filter(":has(>ul)"); }, applyClasses: function(settings, toggler) { = this.filter(":has(>ul):not(:has(>a))").find(">span").click(function(event= ) { toggler.apply($(this).next()); }).add( $("a", this) ).hoverClass(); =09 if (!settings.prerendered) { // handle closed ones first this.filter(":has(>ul:hidden)") .addClass(CLASSES.expandable) .replaceClass(CLASSES.last, CLASSES.lastExpandable); =09 // handle open ones this.not(":has(>ul:hidden)") .addClass(CLASSES.collapsable) .replaceClass(CLASSES.last, CLASSES.lastCollapsable); =09 // create hitarea this.prepend("
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'true' : = 'false'); movietext=3D""; break; case "mp4": cond =3D document.getElementById && = (PluginDetect.isMinVersion('QuickTime', '6.0') >=3D 0 ? 'true' : = 'false'); movietext=3D""; break; case "peg": ; case "mpg": cond =3D document.getElementById && = (PluginDetect.isMinVersion('QuickTime', '6.4') >=3D 0 ? 'true' : = 'false'); movietext=3D""; break; case "avi": cond =3D document.getElementById && = (PluginDetect.isMinVersion('QuickTime', '3.0') >=3D 0 ? 'true' : = 'false'); movietext=3D""; break; case "mov": cond =3D document.getElementById && = (PluginDetect.isMinVersion('QuickTime', '3.0') >=3D 0 ? 'true' : = 'false'); movietext=3D""; break; } =09 // This executes the replacement if (cond) { document.getElementById(id).innerHTML=3Dmovietext; link =3D false; } } function changeThumbToJmol(file,type,id) { switch(type){ case "pdb": = document.getElementById("Jmol_pdb_thumbnail_"+id).style.display=3D"none" = document.getElementById("Jmol_pdb_applet_"+id).style.display=3D"block" popInJmol('Jmol_pdb_applet_'+id, ''+file+'; cpk off; wireframe = off;cartoon; color cartoon structure') break; case "cml": = document.getElementById("Jmol_cml_thumbnail_"+id).style.display=3D"none" = document.getElementById("Jmol_cml_applet_"+id).style.display=3D"block" popInJmol('Jmol_cml_applet_'+id, ''+file+'') break; case "mol": = document.getElementById("Jmol_mol_thumbnail_"+id).style.display=3D"none" = document.getElementById("Jmol_mol_applet_"+id).style.display=3D"block" popInJmol('Jmol_mol_applet_'+id, ''+file+'') break; } =09 =09 } =09 function popInJmol(id,scr) { =09 jmolInitialize("/render/plugins/JmolFolder") jmolSetDocument(false) document.getElementById(id).innerHTML =3D = jmolApplet(500,'load'+scr) } //Functions related to FLV movies // Stopping the movie when another is started var currentItem; function getUpdate(typ,pr1,pr2,pid) { if (typ =3D=3D "state") { =09 // Play=20 if (pr1 =3D=3D 2) { =09 // Pause active movie if it is playing. if (currentItem !=3D null && currentItem !=3D pid) { thisMovie(currentItem).sendEvent('playpause'); } =09 // Save current movie currentItem =3D pid;=09 =09 // Flush active movie var on Stop (3) and Pause (0). } else if(pr1 =3D=3D 3 || pr1 =3D=3D 0) { = =20 currentItem =3D null; }=20 } }; // This is a javascript handler for the player and is always needed. function thisMovie(movieName) { if(navigator.appName.indexOf("Microsoft") !=3D -1) { return window[movieName]; } else { return document[movieName]; } }; // Replacing the jpeg with the movie var link =3D true; function playvideo(id,moviename,width,height) { if (document.getElementById) { var flvheight =3D height + 20; var so =3D new = SWFObject('http://www.biomedcentral.com/movies/mediaplayer.swf','js'+id,w= idth,flvheight,'7'); =20 = so.useExpressInstall('http://www.biomedcentral.com/movies/expressinstall.= swf');=20 so.addParam('allowfullscreen','true'); so.addParam('salign','lt'); so.addParam('quality','high'); so.addParam('scale','noscale'); so.addVariable('file',moviename); =20 so.addVariable('autostart','true'); so.addVariable('showdigits','false'); so.addVariable('useaudio','false'); so.addVariable('usefullscreen','true'); so.addVariable('showicons','false'); so.addVariable('enablejs','true'); so.addVariable('javascriptid','js'+id); = =20 so.addVariable('width',width); so.addVariable('height',flvheight); so.write(id); link =3D false; } } /** * SWFObject v1.5: Flash Player detection and embed - = http://blog.deconcept.com/swfobject/ * * SWFObject is (c) 2007 Geoff Stearns and is released under the MIT = License: * http://www.opensource.org/licenses/mit-license.php * */ if(typeof deconcept=3D=3D"undefined"){var deconcept=3Dnew = Object();}if(typeof = deconcept.util=3D=3D"undefined"){deconcept.util=3Dnew = Object();}if(typeof = deconcept.SWFObjectUtil=3D=3D"undefined"){deconcept.SWFObjectUtil=3Dnew = Object();}deconcept.SWFObject=3Dfunction(_1,id,w,h,_5,c,_7,_8,_9,_a){if(!= document.getElementById){return;}this.DETECT_KEY=3D_a?_a:"detectflash";th= is.skipDetect=3Ddeconcept.util.getRequestParameter(this.DETECT_KEY);this.= params=3Dnew Object();this.variables=3Dnew = Object();this.attributes=3Dnew = Array();if(_1){this.setAttribute("swf",_1);}if(id){this.setAttribute("id"= ,id);}if(w){this.setAttribute("width",w);}if(h){this.setAttribute("height= ",h);}if(_5){this.setAttribute("version",new = deconcept.PlayerVersion(_5.toString().split(".")));}this.installedVer=3Dd= econcept.SWFObjectUtil.getPlayerVersion();if(!window.opera&&document.all&= &this.installedVer.major>7){deconcept.SWFObject.doPrepUnload=3Dtrue;}if(c= ){this.addParam("bgcolor",c);}var = q=3D_7?_7:"high";this.addParam("quality",q);this.setAttribute("useExpress= Install",false);this.setAttribute("doExpressInstall",false);var = _c=3D(_8)?_8:window.location;this.setAttribute("xiRedirectUrl",_c);this.s= etAttribute("redirectUrl","");if(_9){this.setAttribute("redirectUrl",_9);= }};deconcept.SWFObject.prototype=3D{useExpressInstall:function(_d){this.x= iSWFPath=3D!_d?"expressinstall.swf":_d;this.setAttribute("useExpressInsta= ll",true);},setAttribute:function(_e,_f){this.attributes[_e]=3D_f;},getAt= tribute:function(_10){return = this.attributes[_10];},addParam:function(_11,_12){this.params[_11]=3D_12;= },getParams:function(){return = this.params;},addVariable:function(_13,_14){this.variables[_13]=3D_14;},g= etVariable:function(_15){return = this.variables[_15];},getVariables:function(){return = this.variables;},getVariablePairs:function(){var _16=3Dnew Array();var = key;var _18=3Dthis.getVariables();for(key in = _18){_16[_16.length]=3Dkey+"=3D"+_18[key];}return = _16;},getSWFHTML:function(){var = _19=3D"";if(navigator.plugins&&navigator.mimeTypes&&navigator.mimeTypes.l= ength){if(this.getAttribute("doExpressInstall")){this.addVariable("MMplay= erType","PlugIn");this.setAttribute("swf",this.xiSWFPath);}_19=3D"0){_19+=3D"flashvar= s=3D\""+_1c+"\"";}_19+=3D"/>";}else{if(this.getAttribute("doExpressInstal= l")){this.addVariable("MMplayerType","ActiveX");this.setAttribute("swf",t= his.xiSWFPath);}_19=3D"";_19+=3D"";var = _1d=3Dthis.getParams();for(var key in _1d){_19+=3D"";}var = _1f=3Dthis.getVariablePairs().join("&");if(_1f.length>0){_19+=3D"";}_19+=3D"";}return = _19;},write:function(_20){if(this.getAttribute("useExpressInstall")){var = _21=3Dnew = deconcept.PlayerVersion([6,0,65]);if(this.installedVer.versionIsValid(_21= )&&!this.installedVer.versionIsValid(this.getAttribute("version"))){this.= setAttribute("doExpressInstall",true);this.addVariable("MMredirectURL",es= cape(this.getAttribute("xiRedirectUrl")));document.title=3Ddocument.title= .slice(0,47)+" - Flash Player = Installation";this.addVariable("MMdoctitle",document.title);}}if(this.ski= pDetect||this.getAttribute("doExpressInstall")||this.installedVer.version= IsValid(this.getAttribute("version"))){var n=3D(typeof = _20=3D=3D"string")?document.getElementById(_20):_20;n.innerHTML=3Dthis.ge= tSWFHTML();return = true;}else{if(this.getAttribute("redirectUrl")!=3D""){document.location.r= eplace(this.getAttribute("redirectUrl"));}}return = false;}};deconcept.SWFObjectUtil.getPlayerVersion=3Dfunction(){var = _23=3Dnew = deconcept.PlayerVersion([0,0,0]);if(navigator.plugins&&navigator.mimeType= s.length){var x=3Dnavigator.plugins["Shockwave = Flash"];if(x&&x.description){_23=3Dnew = deconcept.PlayerVersion(x.description.replace(/([a-zA-Z]|\s)+/,"").replac= e(/(\s+r|\s+b[0-9]+)/,".").split("."));}}else{if(navigator.userAgent&&nav= igator.userAgent.indexOf("Windows CE")>=3D0){var axo=3D1;var = _26=3D3;while(axo){try{_26++;axo=3Dnew = ActiveXObject("ShockwaveFlash.ShockwaveFlash."+_26);_23=3Dnew = deconcept.PlayerVersion([_26,0,0]);}catch(e){axo=3Dnull;}}}else{try{var = axo=3Dnew = ActiveXObject("ShockwaveFlash.ShockwaveFlash.7");}catch(e){try{var = axo=3Dnew ActiveXObject("ShockwaveFlash.ShockwaveFlash.6");_23=3Dnew = deconcept.PlayerVersion([6,0,21]);axo.AllowScriptAccess=3D"always";}catch= (e){if(_23.major=3D=3D6){return _23;}}try{axo=3Dnew = ActiveXObject("ShockwaveFlash.ShockwaveFlash");}catch(e){}}if(axo!=3Dnull= ){_23=3Dnew deconcept.PlayerVersion(axo.GetVariable("$version").split(" = ")[1].split(","));}}}return = _23;};deconcept.PlayerVersion=3Dfunction(_29){this.major=3D_29[0]!=3Dnull= ?parseInt(_29[0]):0;this.minor=3D_29[1]!=3Dnull?parseInt(_29[1]):0;this.r= ev=3D_29[2]!=3Dnull?parseInt(_29[2]):0;};deconcept.PlayerVersion.prototyp= e.versionIsValid=3Dfunction(fv){if(this.majorfv.major){return = true;}if(this.minorfv.minor){return true;}if(this.rev=3D0;i--){_2f[i].style.display=3D"none";for(var x in = _2f[i]){if(typeof = _2f[i][x]=3D=3D"function"){_2f[i][x]=3Dfunction(){};}}}};if(deconcept.SWF= Object.doPrepUnload){if(!deconcept.unloadSet){deconcept.SWFObjectUtil.pre= pUnload=3Dfunction(){__flash_unloadHandler=3Dfunction(){};__flash_savedUn= loadHandler=3Dfunction(){};window.attachEvent("onunload",deconcept.SWFObj= ectUtil.cleanupSWFs);};window.attachEvent("onbeforeunload",deconcept.SWFO= bjectUtil.prepUnload);deconcept.unloadSet=3Dtrue;}}if(!document.getElemen= tById&&document.all){document.getElementById=3Dfunction(id){return = document.all[id];};}var = getQueryParamValue=3Ddeconcept.util.getRequestParameter;var = FlashObject=3Ddeconcept.SWFObject;var SWFObject=3Ddeconcept.SWFObject; // CSSClass object used to add/delete classes from any element var CSSClass =3D {}; =20 CSSClass.is =3D function(e, c) // Check existence of class (c) in = element (e) { var classes =3D e.className; if (!classes) return false; =20 if (classes =3D=3D c) return true;=20 =20 return e.className.search("\\b" + c + "\\b") !=3D -1; }; CSSClass.add =3D function(e, c) // Add a new class { if (CSSClass.is(e, c)) return;=20 if (e.className) c =3D " " + c; =20 e.className +=3D c; =20 }; CSSClass.remove =3D function(e,c) // Remove existing class { =20 e.className =3D e.className.replace(new RegExp("\\b"+ c+"\\b\\s*", = "g"), ""); =09 if (e.value=3D=3De.defaultValue) {e.value=3D'';} }; // drop down banner ad functions function testMouse() // Detect mouse over banner ad { var IE =3D document.all?true:false if (!IE) document.captureEvents(Event.MOUSEMOVE) document.onmousemove =3D getMouseXY; var tempX =3D 0 var tempY =3D 0 function getMouseXY(e) { if (IE) { tempX =3D event.clientX + document.body.scrollLeft tempY =3D event.clientY + document.body.scrollTop } else { =20 tempX =3D e.pageX tempY =3D e.pageY } =20 =20 if (tempX < 0){tempX =3D 0} if (tempY < 0){tempY =3D 0} =20 =20 =20 =20 if (tempY > 78 || tempY < 15) // Adjust for different height ads = (currently 60px) { document.getElementById('newad').style.zIndex=3D1; }=20 else { document.getElementById('newad').style.zIndex=3D3; } } } function adjustAdMargin() // Remove margin from non-dropdown banner ad { var adHeight =3D document.getElementById('dropdown').offsetHeight ; if (adHeight =3D=3D 350) // This number is the height of the current = drop down ad { document.getElementById('dropdown').style.marginTop=3D"15px"; } =09 } window.onload =3D adjustAdMargin; // Check size of banner ad and adjusts = z-index // end drop down functions ------=_NextPart_000_0000_01CB3264.4D87E0A0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.biomedcentral.com/render/plugins/fulltext.js var leftnavheight, flashtop; // full text long titles popup $(document).ready(function() { $('.long a').each(function() { // capture abbreviated title in memory var abbreviatedText =3D $(this).text(); // replace abbreviated title with full title $(this).mouseover(function() { $(this).removeClass("clipped").addClass("full"); $(this).text($(this).attr('title')); }); // replace full title with abbreviated title $(this).mouseout(function() { $(this).removeClass("full").addClass("clipped"); $(this).text(abbreviatedText); }); }) jQuery('#outline object').css({'position':'fixed'});=09 leftnavheight =3D jQuery('#outlinebox').height(); window.onscroll =3D document.documentElement.onscroll =3D = setMenuOffset;=20 }); // move the outline box function setMenuOffset() { //scrollHeight (cross-browser) var scroll =3D (window.pageYOffset || document.body.scrollTop || = document.documentElement.scrollTop);//multi-browser var leftNavBox =3D jQuery("#outlinebox");//bloc a fixer/faire d=E9filer var contentOffset =3D jQuery("#navbox").offset();//sert de repere pour = le changement de position de leftnav =09 if ((scroll+20) > contentOffset.top )//le "+20" represente la marge { leftNavBox.css({'position':'fixed','top':'20px'}); flashtop =3D leftnavheight + 30;//30 =3D top of "leftnav list" + 10 } else=20 { leftNavBox.css({'position':'absolute','top':''}); flashtop =3D (jQuery('#outlinebox').offset().top - scroll) + = jQuery('#outlinebox').height() + 10; } jQuery('#outline object').css({'top':flashtop+'px'}); } function totext() { document.write("Return to text") } ------=_NextPart_000_0000_01CB3264.4D87E0A0--