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Boswellia

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Brain Tumors


Janssen G, Bode U, Breu H, Dohrn B, Engelbrecht V, Gobel U
Boswellic acids in the palliative therapy of children with progressive or relapsed brain tumors
Klin Padiatr 2000 Jul-Aug;212(4):189-95 

Kirste S, Treier M, Wehrle SJ, Becker G, Abdel-Tawab M, Gerbeth K, Hug MJ, Lubrich B, Grosu AL, Momm F.
Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: A prospective, randomized, placebo-controlled, double-blind pilot trial.
Cancer. 2011 Feb 1. doi: 10.1002/cncr.25945. [Epub ahead of print]
  Abstract |   Related articles


Cancer Research


Safayhi H, Boden SE, Schweizer S, Ammon HP
Concentration-dependent potentiating and inhibitory effects of Boswellia extracts on 5-lipoxygenase product formation in stimulated PMNL
Planta Med 2000 Mar;66(2):110-3 


Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HP
Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase
J Pharmacol Exp Ther 1992 Jun;261(3):1143-6 

Syrovets T, Buchele B, Gedig E, Slupsky JR, Simmet T
Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha
Mol Pharmacol 2000 Jul;58(1):71-81
(PDF Full Text)


Glioblastoma


Mladen Golubic, Naren Nathoo, Richard A. Prayson, Linda Vargo, Judy Bondar, Susana Arrigain, Gene H. Barnett
Increased expression of 5-lipoxygenase in glioblastoma multiforme
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract No. R4983 


Gliomas


Gati I, Bergstrom M, Csoka K, Muhr C, Carlsson J
Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines
Prostaglandins Leukot Essent Fatty Acids 1990 Jun;40(2):117-24


Glaser T, Winter S, Groscurth P, Safayhi H, Sailer ER, Ammon HP, Schabet M, Weller M
Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity
Br J Cancer 1999 May;80(5-6):756-65


D. Hager, H. Dziambor, E. M. App, C. Popa, O. Popa, M. Hertlein
The treatment of patients with high-grade malignant gliomas with RF-hyperthermia
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 470 

Winking M, Sarikaya S, Rahmanian A, Jodicke A, Boker DK
Boswellic acids inhibit glioma growth: a new treatment option?
J Neurooncol 2000 Jan;46(2):97-103 (Abstract+)



Metastatic Tumors


D. F. Flavin
A lipoxygenase inhibitor in breast cancer brain metastases
J Neurooncol. 2006 Sep 26; [Epub ahead of print]
Abstract


Monograph


Barrie Cassileth and K. Simon Yeung
Boswellia (Boswellia Serrata)
01/13/2003 Memorial Sloar-Kettering Cancer Center (HTML Full Text)


Non-Neoplastic Diseases


Gupta I, Parihar A, Malhotra P, Gupta S, Ludtke R, Safayhi H, Ammon HP
Effects of gum resin of Boswellia serrata in patients with chronic colitis
Planta Med 2001 Jul;67(5):391-5 


Non-CNS Tumors


Jing Y, Nakajo S, Xia L, Nakaya K, Fang Q, Waxman S, Han R
Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines
Leuk Res 1999 Jan;23(1):43-50



Non-steroidal anti-infl. agent


Dahmen U, Gu YL, Dirsch O, Fan LM, Li J, Shen K, Broelsch CE
Boswellic acid, a potent antiinflammatory drug, inhibits rejection to the same extent as high dose steroids
Transplant Proc 2001 Feb-Mar;33(1-2):539-41

Singh GB, Atal CK
Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent
Agents Actions 1986 Jun;18(3-4):407-12 


 

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