Integrative Medicine > Boswellia


Brain Tumors

Janssen G, Bode U, Breu H, Dohrn B, Engelbrecht V, Gobel U
Boswellic acids in the palliative therapy of children with progressive or relapsed brain tumors
Klin Padiatr 2000 Jul-Aug;212(4):189-95 (Clinical Study, Abstract)


Cancer Research

Safayhi H, Boden SE, Schweizer S, Ammon HP
Concentration-dependent potentiating and inhibitory effects of Boswellia extracts on 5-lipoxygenase product formation in stimulated PMNL
Planta Med 2000 Mar;66(2):110-3
(Cell Culture Study, Abstract)


Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HP
Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase
J Pharmacol Exp Ther 1992 Jun;261(3):1143-6
(Animal Study, Abstract)

Syrovets T, Buchele B, Gedig E, Slupsky JR, Simmet T
Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha
Mol Pharmacol 2000 Jul;58(1):71-81
(Cell Culture Study, Abstract & PDF Full Text)


Glioblastoma

Mladen Golubic, Naren Nathoo, Richard A. Prayson, Linda Vargo, Judy Bondar, Susana Arrigain, Gene H. Barnett
Increased expression of 5-lipoxygenase in glioblastoma multiforme
Proceedings of the AACR, Volume 44, 2nd ed., July 2003, Abstract No. R4983
(Cell Culture Study)


Gliomas

Gati I, Bergstrom M, Csoka K, Muhr C, Carlsson J
Effects of the 5-lipoxygenase inhibitors AA-863 and U-60,257 on human glioma cell lines
Prostaglandins Leukot Essent Fatty Acids 1990 Jun;40(2):117-24
(Cell Culture Study, Abstract)

Glaser T, Winter S, Groscurth P, Safayhi H, Sailer ER, Ammon HP, Schabet M, Weller M
Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity
Br J Cancer 1999 May;80(5-6):756-65
(Cell Culture Study, Abstract)

D. Hager, H. Dziambor, E. M. App, C. Popa, O. Popa, M. Hertlein
The treatment of patients with high-grade malignant gliomas with RF-hyperthermia
39th ASCO Annual Meeting. Chicago, IL. May 31-June 3, 2003. Abstract No. 470 (Clinical Study)

Winking M, Sarikaya S, Rahmanian A, Jodicke A, Boker DK
Boswellic acids inhibit glioma growth: a new treatment option?
J Neurooncol 2000 Jan;46(2):97-103 (Animal Study, Abstract+)



Metastatic Tumors

D. F. Flavin
A lipoxygenase inhibitor in breast cancer brain metastases
J Neurooncol. 2006 Sep 26; [Epub ahead of print]
Abstract


Monograph

Barrie Cassileth and K. Simon Yeung
Boswellia (Boswellia Serrata)
01/13/2003 Memorial Sloar-Kettering Cancer Center (Monograph, HTML Full Text)


Non-Neoplastic Diseases

Gupta I, Parihar A, Malhotra P, Gupta S, Ludtke R, Safayhi H, Ammon HP
Effects of gum resin of Boswellia serrata in patients with chronic colitis
Planta Med 2001 Jul;67(5):391-5 (Clinical Study, Abstract)


Non-Nervous System Tumors

Jing Y, Nakajo S, Xia L, Nakaya K, Fang Q, Waxman S, Han R
Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines
Leuk Res 1999 Jan;23(1):43-50
(Cell Culture Study, Abstract)


Non-steroidal anti-inflammatory agent

Dahmen U, Gu YL, Dirsch O, Fan LM, Li J, Shen K, Broelsch CE
Boswellic acid, a potent antiinflammatory drug, inhibits rejection to the same extent as high dose steroids
Transplant Proc 2001 Feb-Mar;33(1-2):539-41 (Clinical Study, Reference)

Singh GB, Atal CK
Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent
Agents Actions 1986 Jun;18(3-4):407-12
(Animal Study, Abstract)

 

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