Integrative Medicine > Melatonin


Cancer Research

Blask DE, Dauchy RT, Sauer LA, Krause JA, Brainard GC
Light during darkness, melatonin suppression and cancer progression
Neuroendocrinol Lett 2002 Jul;23 Suppl 2:52-6
(Laboratory Investigation, Abstract)

Lissoni P
Is there a role for melatonin in supportive care?
Support Care Cancer 2002 Mar;10(2):110-6

 Abstract | DBLinks | BL 1:3

Sauer LA, Dauchy RT, Blask DE
Polyunsaturated fatty acids, melatonin, and cancer prevention
Biochem Pharmacol 2001 Jun 15;61(12):1455-62 (Review Article, Abstract)


Glioblastoma

Lissoni P, Meregalli S, Nosetto L, Barni S, Tancini G, Fossati V, Maestroni G
Increased survival time in brain glioblastomas by a radioneuroendocrine strategy with radiotherapy plus melatonin compared to radiotherapy alone
Oncology 1996 Jan-Feb;53(1):43-6
 Abstract | DBLinks | BL 1:3


Gliomas

Rincon Castro LM, Gallant M, Niles LP
Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells
J Neurochem. 2005 Dec;95(5):1227-36. (Laboratory Investigation, Abstract)

Vanesa Martín, Federico Herrera, Pilar Carrera-Gonzalez, Guillermo García-Santos, Isaac Antolín, Jezabel Rodriguez-Blanco and Carmen Rodriguez
Intracellular Signaling Pathways Involved in the Cell Growth Inhibition of Glioma Cells by Melatonin
Cancer Research, 66, 1081-1088, January 15, 2006. (Laboratory Investigation, Abstract)


Metastatic Brain Tumors

Berk L, Berkey B, Rich T, Hrushesky W, Blask D, Gallagher M, Kudrimoti M, McGarry RC, Suh J, Mehta M.
Randomized phase II trial of high-dose melatonin and radiation therapy for rpa class 2 patients with brain metastases (RTOG 0119).
Int J Radiat Oncol Biol Phys. 2007 Apr 5; [Epub ahead of print]
PMID: 17418968 [PubMed - as supplied by publisher]

Lissoni P, Barni S, Ardizzoia A, Tancini G, Conti A, Maestroni G
A randomized study with the pineal hormone melatonin versus supportive care alone in patients with brain metastases due to solid neoplasms
Cancer 1994 Feb 1;73(3):699-701 (
Clinical Study, Abstract)


Monograph

Barrie Cassileth and K. Simon Yeung
Melatonin (N-acetyl-methoxytryptamine)
10/11/2002 Memorial Sloar-Kettering Cancer Center (Monograph, HTML Full Text)


Non-Nervous System Tumors

Barni S, Lissoni P, Cazzaniga M, Ardizzoia A, Meregalli S, Fossati V, Fumagalli L, Brivio F, Tancini G
A randomized study of low-dose subcutaneous interleukin-2 plus melatonin versus supportive care alone in metastatic colorectal cancer patients progressing under 5-fluorouracil and folates
Oncology 1995 May-Jun;52(3):243-5 (Clinical Study, Abstract)

Lissoni P, Chilelli M, Villa S, Cerizza L, Tancini G
Five years survival in metastatic non-small cell lung cancer patients treated with chemotherapy alone or chemotherapy and melatonin: a randomized trial
J Pineal Res. 2003 Aug;35(1):12-5 (Clinical Study, Abstract)

Lissoni P, Rovelli F, Malugani F, Bucovec R, Conti A, Maestroni GJ
Anti-angiogenic activity of melatonin in advanced cancer patients
Neuroendocrinol Lett 2001;22(1):45-7 (Clinical Study, Abstract)

Lissoni P, Barni S, Mandala M, Ardizzoia A, Paolorossi F, Vaghi M, Longarini R, Malugani F, Tancini G
Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status
Eur J Cancer 1999 Nov;35(12):1688-92 (Clinical Study, Abstract)

Lissoni P, Paolorossi F, Ardizzoia A, Barni S, Chilelli M, Mancuso M, Tancini G, Conti A, Maestroni GJ
A randomized study of chemotherapy with cisplatin plus etoposide versus chemoendocrine therapy with cisplatin, etoposide and the pineal hormone melatonin as a first-line treatment of advanced non-small cell lung cancer patients in a poor clinical state
J Pineal Res 1997 Aug;23(1):15-9 (Clinical Study, Abstract)

Lissoni P, Brivio O, Brivio F, Barni S, Tancini G, Crippa D, Meregalli S
Adjuvant therapy with the pineal hormone melatonin in patients with lymph node relapse due to malignant melanoma
J Pineal Res 1996 Nov;21(4):239-42 (Clinical Study, Abstract)

Lissoni P, Barni S, Ardizzoia A, Paolorossi F, Crispino S, Tancini G, Tisi E, Archili C, De Toma D, Pipino G, et al
Randomized study with the pineal hormone melatonin versus supportive care alone in advanced nonsmall cell lung cancer resistant to a first-line chemotherapy containing cisplatin
Oncology 1992;49(5):336-9 (Clinical Study, Abstract)

Neri B, de Leonardis V, Gemelli MT, di Loro F, Mottola A, Ponchietti R, Raugei A, Cini G
Melatonin as biological response modifier in cancer patients
Anticancer Res 1998 Mar-Apr;18(2B):1329-32 (Clinical Study, Abstract)

 

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