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CLASSIFICATION



CLASSIFICATION OF TUMORS OF THE CNS



THE 2016 WHO CLASSIFICATION OF TUMORS OF THE CNS (Louis DN et al, 2016)






CENTRAL NERVOUS SYSTEM TUMORS

GLIOMAS


CASE REPORTS

HIGH-GRADE GLIOMAS


CLASSIFICATION

LOW-GRADE GLIOMAS


DIAGNOSIS

GLIOMATOSIS CEREBRI


EPIDEMIOLOGY, RISK FACTORS



ETIOLOGY, PATHOGENESIS, PATHOLOGY

OTHER CNS TUMORS


FOLLOW-UP, QUALITY OF LIFE

GLIOFIBROMA


INTEGRATIVE MEDICINE

MEDULLOMYOBLASTOMA


OVERALL MANAGEMENT

PRIMARY INTRACRANIAL MALIGNANT MELANOMA


PROGNOSIS

SIMPSON-GOLABI-BEHMEL SYNDROME TYPE 1


TREATMENT

SPINAL CORD TUMORS




[1; 2]

DIFFUSE ASTROCYTIC AND OLIGODENDROGLIAL TUMORS

OTHER ASTROCYTIC TUMORS


DIFFUSE ASTROCYTOMA

PILOCYTIC ASTROCYTOMA


ANAPLASTIC ASTROCYTOMA

PILOMYXOID ASTROCYTOMA


GLIOBLASTOMA

SUBEPENDYMAL GIANT CELL ASTROCYTOMA


GIANT CELL GLIOBLASTOMA

PLEOMORPHIC XANTHOASTROCYTOMA


GLIOSARCOMA

ANAPLASTIC PLEOMORPHIC XANTOASTROCYTOMA


EPITHELIOID GLIOBLASTOMA


[3]

DIFFUSE MIDLINE GLIOMA (Braistem glioma, Diffuse intrinsic pontine glioma)

EPENDYMAL TUMORS


OLIGODENDROGLIOMAS

SUBEPENDYMOMA


OLIGODENDROGLIOMA

MYXOPAPILLARY EPENDYMOMA


ANAPLASTIC OLIGODENDROGLIOMA

EPENDYMOMA


OLIGOASTROCYTOMAS

ANAPLASTIC EPENDYMOMA


OLIGOASTROCYTOMA



ANAPLASTIC OLIGOASTROCYTOMA





[4;5]

OTHER GLIOMAS

CHOROID PLEXUS TUMORS


CHORDOID GLIOMA OF THE THIRD VENTRICLE

CHOROID PLEXUS PAPILLOMA


ANGIOCENTRIC GLIOMA

ATYPICAL CHOROID PLEXUS PAPILLOMA


ASTROBLASTOMA

CHOROID PLEXUS CARCINOMA




[6;7]

NEURONAL AND MIXED NEURONAL-GLIAL TUMORS

TUMORS OF THE PINEAL REGION


DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR

PINEOCYTOMA


GANGLIOCYTOMA

PINEAL PARENCHYMAL TUMOR OF INTERMEDIATE DIFFERENTIATION


GANGLIOGLIOMA

PINEOBLASTOMA


ANAPLASTIC GANGLIOGLIOMA

PAPILLARY TUMOR OF THE PINEAL REGION


DYSPLASTIC CEREBELLAR GANGLIOCYTOMA (LHERMITTE-DUCLOID DISEASE)


[8]

DESMOPLASTIC INFANTILE ASTROCYTOMA AND GANGLIOGLIOMA

EMBRYONAL TUMORS


PAPILLARY GLIONEURAL TUMOR

MEDULLOBLASTOMA


ROSETTE-FORMING GLIONEURONAL TUMOR

EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES, C19MC-ALTERED


DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR

CNS EMBRYONAL TUMOR


CENTRAL NEUROCYTOMA

ATYPICAL TERATOID/RHABDOID TUMOR


EXTRAVENTRICULAR NEUROCYTOMA



CEREBELLAR LIPONEUROCYTOMA



PARAGANGLIOMA





[9;10]

TUMORS OF THE CRANIAL AND PARASPINAL NERVES

MENINGIOMAS


SCHWANNOMA

MENINGIOMA


MELANOTIC SCHWANNOMA

MENINGIOMA VARIANTS


NEUROFIBROMA

MENINGOTHELIAL MENINGIOMA


PERINEURINOMA

ANAPLASTIC (MALIGNANT) MENINGIOMA


HYBRID NERVE SHEATH TUMORS



MALIGNANT PERIFERAL NERVE SHEATH TUMOR





[11;12]

MESENCHYMAL, NON MENINGOTHELIAL TUMORS

MELANOCYTIC TUMORS


HEMANGIOPERICYTOMA

MENINGEAL MELANOCYTOSIS


HEMANGIOMA

MENINGEAL MELANOMATOSIS


EWING SARCOMA / PERIPHERAL PNET

MENINGEAL MELANOCYTOMA


RHABDOMYOSARCOMA

MENINGEAL MELANOMA




[13;14]

LYMPHOMAS

HISTIOCYTIC TUMORS


DIFFUSE LARGE B-CELL LYMPHOMA OF THE CNS

LANGERHANS CELL HISTIOCYTOSIS


IMMUNODEFICIENCY-ASSOCIATED CNS LYMPHOMAS

ERDHEIM-CHESTER DISEASE


INTRAVASCULAR LARGE B-CELL LYMPHOMA

ROSAI-DORFMAN DISEASE


MISCELLANEOUS RARE LYMPHOMAS INTHECNS

JUVENILE XANTHOGRANULOMA


MALT LYMPHOMA OF THE DURA

HISTIOCYTIC SARCOMA




[15;16]

GERM CELL TUMORS

FAMILIAL TUMOR SYNDROMES


GERMINOMA

NEUROFIBROMATOSIS TYPE 1


EMBRYONAL CARCINOMA

NEUROFIBROMATOSIS TYPE 2


YOLK SAC TUMOR

SCHWANNOMATOSIS


CHORIOCARCINOMA

VON HIPPEL-LINDAU DISEASE


TERATOMA

TUBEROUS SCLEROSIS


TERATOMA WITH MALIGNANT TRANSFORMATION

LI-FRAUMENI SYNDROME


MIXED GERM CELL TUMOR

COWDEN SYNDROME



TURCOT SYNDROME



NAEVOID BASAL CELL CARCINOMA SYNDROME



RHABDOID TUMOUR PREDISPOSITION SYNDROME




[17;18]

TUMORS OF THE SELLAR REGION

METASTATIC TUMORS


CRANIOPHARYNGIOMA



GRANULAR CELL TUMOUR OF THE SELLAR REGION



PITUICYTOMA



SPINDLE CELL ONCOCYTOMA