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Contents



OVERVIEW


GRADE II AND GRADE III GLIOMAS




EXTERNAL SECTIONS


CAR-ARMED CELL THERAPY


DRUG DELIVERY


DRUG REPURPOSING


IMMUNOTHERAPY


RADIOTHERAPY


SONODYNAMIC THERAPY


SURGERY


TARGETED THERAPY


THERMAL THERAPY



Overview

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Alkins RD, Mainprize TG.
High-Intensity Focused Ultrasound Ablation Therapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 39-47 (DOI:10.1159/000469678). Published online: July 10, 2018.
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Butowski N.
Novel and Prospective Molecular Targets for Therapy of Intracranial Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 66-78 (DOI:10.1159/000469681). Published online: July 10, 2018.
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Combs SE.
Proton and Carbon Ion Therapy of Intracranial Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 57-65 (DOI:10.1159/000469680). Published online: July 10, 2018.
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Goldbrunner R, Ruge M, Kocher M, Lucas CW, Galldiks N, Grau S.
The Treatment of Gliomas in Adulthood.
Dtsch Arztebl Int. 2018 May 21;115(20-21):356-364. doi: 10.3238/arztebl.2018.0356.
Source | Abstract | Full text | Similar articles



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Ho ALK, Jena R.
Re-irradiation in the Brain: Primary Gliomas.
Clin Oncol (R Coll Radiol). 2018 Feb;30(2):124-136. doi: 10.1016/j.clon.2017.11.006.
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Iwami K, Natsume A, Wakabayashi T.
Cytokine Therapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 79-89 (DOI:10.1159/000469682). Published online: July 10, 2018.
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Kaneko S, Fujimoto S, Yamaguchi H, Yamauchi T, Yoshimoto T, Tokuda K.
Photodynamic Therapy of Malignant Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 1-13. (DOI:10.1159/000469675). Published online: July 10, 2018.
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Karampelas I, Sloan A.E.
Laser-Induced Interstitial Thermotherapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 14-26 (DOI:10.1159/000469676). Published online: July 10, 2018.
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Kim JW, Chang AL, Kane JR, Young JS, Qiao J, Lesniak MS.
Gene Therapy and Virotherapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 112-123 (DOI:10.1159/000469685). Published online: July 10, 2018.
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Li G, Qin Z, Chen Z, Xie L, Wang R, Zhao H.
Tumor Microenvironment in Treatment of Glioma.
Open Med (Wars). 2017 Aug 12;12:247-251. doi: 10.1515/med-2017-0035. eCollection 2017.
Source | Abstract | Full text | Similar articles



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Martynov BV, Kholyavin AI, Nizkovolos VB, Parfenov VE, Trufanov GE, Svistov DV.
Stereotactic Cryodestruction of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 27-38 (DOI:10.1159/000469677). Published online: July 10, 2018.
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Parker Kerrigan BC, Hossain A, Yamashita S, Lang FF.
Stem Cell Therapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 124-151 (DOI:10.1159/000469686). Published online: July 10, 2018.
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Santiago-Dieppa DR, Gonda DD, Cheung VJ, Steinberg JA, Carter BS, Chen CC.
Extracellular Vesicles as a Platform for Glioma Therapeutic Development
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 172-179 (DOI:10.1159/000469689). Published online: July 10, 2018.
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Uhm JH, Porter AB.
Treatment of Glioma in the 21st Century: An Exciting Decade of Postsurgical Treatment Advances in the Molecular Era.
Mayo Clin Proc. 2017 Jun;92(6):995-1004. doi: 10.1016/j.mayocp.2017.01.010
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IMMUNOTHERAPY



Aquino D, Gioppo A, Finocchiaro G, Bruzzone MG, Cuccarini V.
MRI in Glioma Immunotherapy: Evidence, Pitfalls, and Perspectives.
J Immunol Res. 2017;2017:5813951. doi: 10.1155/2017/5813951. Epub 2017 Apr 20.
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Eissa IR, Bustos-Villalobos I, Ichinose T, Matsumura S, Naoe Y, Miyajima N, Morimoto D, Mukoyama N, Zhiwen W, Tanaka M, Hasegawa H, Sumigama S, Aleksic B, Kodera Y, Kasuya H.
The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers.
Cancers (Basel). 2018 Sep 26;10(10). pii: E356. doi: 10.3390/cancers10100356.
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Everson RG, Antonios JP, Liau L.M.
Cell-Based Immunotherapy of Gliomas
Prog Neurol Surg. Basel, Karger, 2018, vol 32, pp 90-100 (DOI:10.1159/000469683). Published online: July 10, 2018.
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Platten M, Reardon DA.
Concepts for Immunotherapies in Gliomas.
Semin Neurol. 2018 Feb;38(1):62-72. doi: 10.1055/s-0037-1620274. Epub 2018 Mar 16.
Source | Abstract | Full text | Similar articles




Platten M, Bunse L, Wick W, Bunse T.
Concepts in glioma immunotherapy.
Cancer Immunol Immunother. 2016 Jul 26. [Epub ahead of print]
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Hanaei S, Afshari K, Hirbod-Mobarakeh A, Mohajer B, Amir Dastmalchi D, Rezaei N.
Therapeutic efficacy of specific immunotherapy for glioma: a systematic review and meta-analysis.
Rev Neurosci. 2018 Jun 27;29(4):443-461. doi: 10.1515/revneuro-2017-0057.
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Weant MP, Jesús CM, Yerram P.
Immunotherapy in Gliomas.
Semin Oncol Nurs. 2018 Dec;34(5):501-512. doi: 10.1016/j.soncn.2018.10.011. Epub 2018 Nov 2.
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ANTINEOPLASTIC EFFECTS OF ANTIEPILEPTIC DRUGS


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Li Z, Xia Y, Bu X, Yang D, Yuan Y, Guo X, Zhang G, Wang Z, Jiao J.
Effects of valproic acid on the susceptibility of human glioma stem cells for TMZ and ACNU.
Oncol Lett. 2018 Jun;15(6):9877-9883. doi: 10.3892/ol.2018.8551. Epub 2018 Apr 20.
Source | Abstract | Full text | Similar articles




Rizzo A, Donzelli S, Girgenti V, Sacconi A, Vasco C, Salmaggi A, Blandino G, Maschio M, Ciusani E.
In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells.
J Exp Clin Cancer Res. 2017 Jun 6;36(1):76. doi: 10.1186/s13046-017-0546-9.
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BRAIN PENETRANCE OF ANTICANCER DRUGS


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Levin VA, Ellingson BM.
Understanding Brain Penetrance of Anticancer Drugs.
Neuro Oncol. 2018 Feb 21. doi: 10.1093/neuonc/noy018. [Epub ahead of print]
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CHEMOTHERAPY




MITOXANTRONE



Ellis JA, Cooke J, Singh-Moon RP, Wang M, Bruce JN, Emala CW, Bigio IJ, Joshi S.
Safety, feasibility, and optimization of intra-arterial mitoxantrone delivery to gliomas.
J Neurooncol. 2016 Dec;130(3):449-454. Epub 2016 Aug 30.
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TEMOZOLOMIDE




Temodex


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Karlsson I, Veevnik D, Fedulov A, Yurkshtovich N, Yurkshtovich T, Pejler G, Lokot I.
Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival of glioma patients irrespectively of the MGMT methylation status.
Neoplasma. 2018 Dec 12. pii: 180613N393. doi: 10.4149/neo_2018_180613N393. [Epub ahead of print]
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HIPPOCAMPUS



Karunamuni RA, Seibert TM, White NS, McEvoy L, Farid N, Brewer J, Dale AM, McDonald CR, Hattangadi-Gluth JA.
Abnormalities in hippocampal volume of glioma patients prior to radiotherapy.
Acta Oncol. 2017 Mar;56(3):427-430. doi: 10.1080/0284186X.2017.1280847. Epub 2017 Feb 3.
Source | Abstract | Full text | Similar articles



INTRANASAL DRUG DELIVERY


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Fan Y, Chen M, Zhang J, Maincent P, Xia X, Wu W.
Updated Progress of Nanocarrier-Based Intranasal Drug Delivery Systems for Treatment of Brain Diseases.
Crit Rev Ther Drug Carrier Syst. 2018;35(5):433-467. doi: 10.1615/CritRevTherDrugCarrierSyst.2018024697.
Source | Abstract | Similar articles



MGMT



Li Q, Guo J, Wang W, Wang D.
Relationship between MGMT gene expression and treatment effectiveness and prognosis in glioma.
Oncol Lett. 2017 Jul;14(1):229-233. doi: 10.3892/ol.2017.6123. Epub 2017 May 5.
Source | Abstract | Full text | Similar articles



NERVE GROWTH FACTOR



Falsini B, Chiaretti A, Rizzo D, Piccardi M, Ruggiero A, Manni L, Soligo M, Dickmann A, Federici M, Salerni A, Timelli L, Guglielmi G, Lazzareschi I, Caldarelli M, Galli-Resta L, Colosimo C, Riccardi R.
Nerve growth factor improves visual loss in childhood optic gliomas: a randomized, double-blind, phase II clinical trial.
Brain. 2016 Feb;139(Pt 2):404-14. doi: 10.1093/brain/awv366. Epub 2016 Jan 14.
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VENOUS THROMBOEMBOLISM



Al Megren M, De Wit C, Al Qahtani M, Le Gal G, Carrier M.
Management of venous thromboembolism in patients with glioma.
Thromb Res. 2017 Jun 8;156:105-108. doi: 10.1016/j.thromres.2017.06.010. [Epub ahead of print]
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Laboratory investigations




RADIOTHERAPY




OVERCOMING RADIORESISTANCE BY ERADICATING STEM CELLS


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Chiblak S, Tang Z, Lemke D, Knoll M, Dokic I, Warta R, Moustafa M, Mier W, Brons S, Rapp C, Muschal S, Seidel P, Bendzsus M, Adeberg S, Wiestler OD, Haberkorn U, Debus J, Herold-Mende C, Wick W, Abdollahi A.
Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche.
JCI Insight. 2019 Jan 24;4(2). pii: 123837. doi: 10.1172/jci.insight.123837. [Epub ahead of print]
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VALPROIC ACID


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Riva G, Cilibrasi C, Bazzoni R, Cadamuro M, Negroni C, Butta V, Strazzabosco M, Dalprà L, Lavitrano M, Bentivegna A.
Valproic Acid Inhibits Proliferation and Reduces Invasiveness in Glioma Stem Cells Through Wnt/β Catenin Signalling Activation.
Genes (Basel). 2018 Oct 26;9(11). pii: E522. doi: 10.3390/genes9110522.
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Clinical investigations




RADIATION THERAPY


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Jhaveri J, Cheng E, Tian S, Buchwald Z, Chowdhary M, Liu Y, Gillespie TW, Olson JJ, Diaz AZ, Voloschin A, Eaton BR, Crocker IR, McDonald MW, Curran WJ, Patel KR.
Proton vs. Photon Radiation Therapy for Primary Gliomas: An Analysis of the National Cancer Data Base.
Front Oncol. 2018 Nov 28;8:440. doi: 10.3389/fonc.2018.00440. eCollection 2018.
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Recurrent tumors




INTRANASAL THERAPY


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Chen TC, da Fonseca CO, Schönthal AH.
Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development.
Int J Mol Sci. 2018 Dec 6;19(12). pii: E3905. doi: 10.3390/ijms19123905.
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RE-IRRADIATION



Krauze A, Attia A, Braunstein S, Chan M, Combs S, Fietkau R, Fiveash J, Flickinger J, Grosu A, Howard S, Nieder C, Niyazi M, Rowe L, Smart DD, Tsien C, Camphausen K.
Expert consensus on re-irradiation for recurrent glioma.
Radiat Oncol. 2017 Dec 1;12(1):194. doi: 10.1186/s13014-017-0928-3.
Source | Abstract | Full text | Similar articles



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Post CCB, Kramer MCA, Smid EJ, van der Weide HL, Kleynen CE, Heesters MAAM, Verhoeff JJC.
Patterns of re-irradiation for recurrent gliomas and validation of a prognostic score.
Radiother Oncol. 2018 Nov 13. pii: S0167-8140(18)33575-8. doi: 10.1016/j.radonc.2018.10.034. [Epub ahead of print]
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RE-IRRADIATION AFTER SECOND SURGERY


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Combs SE, Kessel KA, Hesse J, Straube C, Zimmer C, Schmidt-Graf F, Schlegel J, Gempt J, Meyer B.
Moving Second Courses of Radiotherapy Forward: Early Re-Irradiation After Surgical Resection for Recurrent Gliomas Improves Efficacy With Excellent Tolerability.
Neurosurgery. 2018 Feb 16. doi: 10.1093/neuros/nyx629. [Epub ahead of print]
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RADIOSURGERY


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Sadik ZHA, Hanssens PEJ, Verheul JB, Beute GN, Te Lie S, Leenstra S, Ardon H.
Gamma knife radiosurgery for recurrent gliomas.
J Neurooncol. 2018 Sep 6. doi: 10.1007/s11060-018-2988-0. [Epub ahead of print]
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TOCA 511



[No authors listed]
Treating Recurrent Glioma with Toca 511.
Cancer Discov. 2017 Nov 8. doi: 10.1158/2159-8290.CD-NB2017-157. [Epub ahead of print]
Source | Abstract | Full text | Similar articles



Grade II and grade III gliomas


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Lin AJ, Campian JL, Hui C, Rudra S, Rao YJ, Thotala D, Hallahan D, Huang J.
Impact of concurrent versus adjuvant chemotherapy on the severity and duration of lymphopenia in glioma patients treated with radiation therapy.
J Neurooncol. 2017 Nov 16. doi: 10.1007/s11060-017-2668-5. [Epub ahead of print]
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Picca A, Berzero G, Sanson M.
Current therapeutic approaches to diffuse grade II and III gliomas.
Ther Adv Neurol Disord. 2018 Jan 17;11:1756285617752039. doi: 10.1177/1756285617752039. eCollection 2018.
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van den Bent MJ, Klein M, Smits M, Reijneveld JC, French PJ, Clement P, de Vos FYF, Wick A, Mulholland PJ, Taphoorn MJB, Lewis J, Weller M, Chinot OL, Kros JM, de Heer I, Verschuere T, Coens C, Golfinopoulos V, Gorlia T, Idbaih A.
Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial.
Lancet Oncol. 2018 Aug 13. pii: S1470-2045(18)30362-0. doi: 10.1016/S1470-2045(18)30362-0. [Epub ahead of print]
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Wood H.
Addition of bevacizumab fails to improve on temozolomide alone for glioma therapy.
Nat Rev Neurol. 2018 Aug 29. doi: 10.1038/s41582-018-0067-y. [Epub ahead of print]
Comment on: Van den Bent MJ et al.,Bevacizumab and temozolomide in patients with first recurrence of WHO grade II and III glioma, without 1p/19q co-deletion (TAVAREC): a randomised controlled phase 2 EORTC trial. [Lancet Oncol. 2018 Aug 13].
Source | Full text | Similar articles