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Neuronal and mixed neuronal-glial tumors


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Contents



GROUP LEVEL LITERATURE SECTIONS
■ CASE REPORTS
■ CLASSIFICATION
■ DIAGNOSIS, PRESENTATION
■ EPIDEMIOLOGY, RISK FACTORS
■ ETIOLOGY, PATHOGENESIS, PATHOLOGY
■ FOLLOW-UP, SIDE EFFECTS, QUALITY OF LIFE
■ INTEGRATIVE MEDICINE
■ OVERALL MANAGEMENT
■ PROGNOSIS, OUTCOMES
■ TREATMENT

GROUP COMPONENTS
■ DYSEMBRYOPLASTIC NEUROEPITHELIAL TUMOR
■ GANGLIOCYTOMA
■ GANGLIOGLIOMA
■ ANAPLASTIC GANGLIOGLIOMA
■ DYSPLASTIC CEREBELLAR GANGLIOCYTOMA (LHERMITTE-DUCLOID DISEASE)
DESMOPLASTIC INFANTILE ASTROCYTOMA AND GANGLIOGLIOMA
PAPILLARY GLIONEURAL TUMOR
ROSETTE-FORMING GLIONEURONAL TUMOR
DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR
CENTRAL NEUROCYTOMA
EXTRAVENTRICULAR NEUROCYTOMA
CEREBELLAR LIPONEUROCYTOMA
■ PARAGANGLIOMA

Overall management


Review

Chen J, Dahiya SM.
Update on Circumscribed Gliomas and Glioneuronal Tumors.
Surg Pathol Clin. [2020 May 7]. 2020;13(2):249-266. Doi 10.1016/j.path.2020.02.004. _


Well-circumscribed intra-axial CNS tumors encompass a wide variety of gliomas and glioneuronal tumors, usually corresponding to WHO grades I and II. Nonetheless, sometimes high-grade 'diffuse' gliomas such as gliosarcoma and giant cell glioblastoma can be relatively circumscribed but are often found to have foci of diffuse infiltration on careful examination, harboring distinct molecular alterations. These tumors are excluded from the discussion in this chapter with the current review emphasizing on lower-grade entities to include a brief description of their histology and associated molecular findings. Like elsewhere in brain biopsy evaluation, imaging is crucial and acts as a surrogate to gross examination. Given the circumscribed nature of these tumors, surgery alone is the mainstay treatment in most entities.



Ganglioglioma




Case reports



Scheuermann A, Belongia M, Lawlor MW, Suchi M, Kaufman B, Vasudevaraja V, Serrano J, Snuderl M, Knipstein J.
Ganglioglioma in a Survivor of Infantile Glioblastoma.
J Pediatr Hematol Oncol. [2019 Jan 22]. 2020;42(1):e56-e60. Doi 10.1097/MPH.0000000000001417. _




Valvi S, Ziegler DS.
Ganglioglioma Arising From Desmoplastic Medulloblastoma: A Case Report and Review of Literature.
Pediatrics. 2017 Mar. 2017;139(3):e20161403. Doi 10.1542/peds.2016-1403. _



Anaplastic ganglioglioma




Prognosis



Terrier LM, Bauchet L, Rigau V, Amelot A, Zouaoui S, Filipiak I, Caille A, Almairac F, Aubriot-Lorton MH, Bergemer-Fouquet AM, Bord E, Cornu P, Czorny A, Dam Hieu P, Debono B, Delisle MB, Emery E, Farah W, Gauchotte G, Godfraind C, Guyotat J, Irthum B, Janot K, Le Reste PJ, Liguoro D, Loiseau H, Lot G, Lubrano V, Mandonnet E, Menei P, Metellus P, Milin S, Muckenstrum B, Roche PH, Rousseau A, Uro-Coste E, Vital A, Voirin J, Wager M, Zanello M, François P, Velut S, Varlet P, Figarella-Branger D, Pallud J, Zemmoura I; Club de Neuro-Oncologie of the Société Française de Neurochirurgie.
Natural course and prognosis of anaplastic gangliogliomas: a multicenter retrospective study of 43 cases from the French Brain Tumor Database.
Neuro Oncol. [2016 Aug 30]. 2017;19(5):678‐688. Doi10.1093/neuonc/now186. _



Dysplastic Cerebellar Gangliocytoma (Lhermitte-Ducloid Disease)




Case reports



Ma J, Jia G, Chen S, Jia W.
Clinical Perspective on Dysplastic Gangliocytoma of the Cerebellum (Lhermitte-Duclos Disease).
World Neurosurg. [2018 Oct 23]. 2019;122:16-23. Doi 10.1016/j.wneu.2018.10.085. _



Rosette-Forming Glioneuronal Tumor




Overall management



Yang C, Fang J, Li G, Li S, Ha T, Wang J, Yang B, Yang J, Xu Y.
Histopathological, molecular, clinical and radiological characterization of rosette-forming glioneuronal tumor in the central nervous system.
Oncotarget. 2017 Nov 24. 2017;8(65):109175‐109190. Doi 10.18632/oncotarget.22646. _



Diffuse leptomeningeal glioneuronal tumor




Case reports



Tiwari S, Yadav T, Pamnani J, Mathew JM, Elhence P, Praneeth K, Vedant D, Khera PS, Garg P, Vyas V.
Diffuse Leptomeningeal Glioneuronal Tumor: A Unique Leptomeningeal Tumor Entity.
World Neurosurg. [2019 Dec 30]. 2019;135:297-300. Doi 10.1016/j.wneu.2019.12.119. _




Xu H, Chen F, Zhu H, Luo L, Zhang R.
Diffuse leptomeningeal glioneuronal tumor in a Chinese adult: a novel case report and review of literature
Acta Neurol Belg. [2019 Dec 24]. 2020;120(2):247-256. Doi10.1007/s13760-019-01262-9. _
Erratum
in Acta Neurol Belg. [2020 Jan 22]. 2020;10.1007/s13760-020-01278-6. Doi 10.1007/s13760-020-01278-6. _



Central neurocytoma




Case reports



Karthigeyan M, Gupta K, Salunke P.
Pediatric Central Neurocytoma: A Short Series With Literature Review.
J Child Neurol. [2016 Sep 23]. 2017;32(1):53-59. Doi 10.1177/0883073816668994. _




Runderawala H, Kantharia A, Oak P, Mahore A.
Central Neurocytoma - A Rare Brain Tumor.
J Assoc Physicians India. 2018 Apr. 2018;66(4):77‐78. _



Overall management



Lee SJ, Bui TT, Chen CH, Lagman C, Chung LK, Sidhu S, Seo DJ, Yong WH, Siegal TL, Kim M, Yang I.
Central Neurocytoma: A Review of Clinical Management and Histopathologic Features.
Brain Tumor Res Treat. [2016 Oct 31]. 2016;4(2):49-57. Doi 10.14791/btrt.2016.4.2.49. _



Desmoplastic infantile astrocytoma and ganglioglioma




Case reports



Narayan V, Savardekar AR, Mahadevan A, Arivazhagan A, Appaji L.
Unusual Occurrence of Multifocal Desmoplastic Infantile Astrocytoma: A Case Report and Review of the Literature.
Pediatr Neurosurg. [2017 Feb 22]. 2017;52(3):173-180. Doi 10.1159/000455926. _




Samkari A, Alzahrani F, Almehdar A, Algahtani H.
Desmoplastic infantile astrocytoma and ganglioglioma: case report and review of the literature.
Clin Neuropathol. [2016 Sep 26]. 2017;36(1):31‐40. Doi 10.5414/NP300945. _



Cerebellar liponeurocytoma




Case reports



Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M.
Liponeurocytoma of the cerebello-pontine angle.
World Neurosurg. [2018 Jan 8]. 2018;112:18-24. Doi 10.1016/j.wneu.2018.01.012. _



Etiology, Pathogenesis, Pathology



Xu L, Du J, Wang J, Fang J, Liu Z, He Y, Li G.
The clinicopathological features of liponeurocytoma.
Brain Tumor Pathol. [2017 Feb 24]. 2017;34(1):28-35. Doi 10.1007/s10014-017-0279-7. _