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Other astrocytic tumors


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CONTENTS



CASE REPORTS
CLASSIFICATION
DIAGNOSIS
EPIDEMIOLOGY, RISK FACTORS
ETIOLOGY, PATHOGENESIS, PATHOLOGY
FOLLOW-UP, QUALITY OF LIFE
INTEGRATIVE MEDICINE
OVERALL MANAGEMENT
PROGNOSIS
TREATMENT

GROUP COMPONENTS:
PILOCYTIC ASTROCYTOMA
PILOMYXOID ASTROCYTOMA
SUBEPENDYMAL GIANT CELL ASTROCYTOMA (SEGA)
PLEOMORPHIC XANTHOASTROCYTOMA (PXA)
ANAPLASTIC PLEOMORPHIC XANTOASTROCYTOMA




EXTERNAL SECTIONS


PLEOMORPHIC XANTHOASTROCYTOMA





Tumor Group




Case reports



Lundar T, Due-Tønnessen BJ, Fric R, Due-Tønnessen P.
Postoperative radiotherapy for pediatric brain tumor: a lesson learned from treatment of a 5-year-old girl for posterior fossa astrocytoma (WHO1) in 1967.
Acta Neurochir (Wien). [2018 Jul 26]. 2018;160(10):2065-2066. Doi 10.1007/s00701-018-3636-3. _



Pilocytic astrocytoma




Case reports




ENLARGEMENT FOLLOWING IRRADIATION



Trunin Y, Golanov AV, Kostjuchenko VV, Galkin M, Konovalov AN.
Pilocytic Astrocytoma Enlargement Following Irradiation: Relapse or Pseudoprogression?
Cureus. Published 2017 Feb 21. 2017;9(2):e1045. Doi 10.7759/cureus.1045. _



FOLLOWING A BRAINSTEM GLIOMA



Satyarthee GD, Sudhan MD, Mehta VS.
Pilocytic Midbrain Astrocytoma Presenting with Fresh Bleed after Twenty-one-years Survival Following First Surgery: A Unique Case of Longest Brainstem Glioma Survival.
J Neurosci Rural Pract. [2016 Dec 26]. 2016;7(Suppl 1):S88-S90. Doi: 10.4103/0976-3147.196452. _



INTRAVENTRICULAR TUMOR



Sattar S, Akhunzada NZ, Javed G, Uddin Z, Khan YA.
Pilocytic astrocytoma: A rare presentation as intraventricular tumor.
Surg Neurol Int. 2017 Jun 13. 2017;8:116. Doi 10.4103/sni.sni_468_16. _



LEPTOMENINGEAL METASTASIS



Grahnke KA, Heiferman DM, Borys E, Melian E, Barton KP, Lukas RV, Shaikh N, Leonetti JP, Anderson DE.
Delayed leptomeningeal metastasis of an adult anaplastic pilocytic astrocytoma.
Brain Tumor Pathol. [2018 Jan 13]. 2018;35(2):123-126. Doi 10.1007/s10014-017-0306-8. _



OPTIC PILOCYTIC ASTROCYTOMA



Bin Abdulqader S, Al-Ajlan Z, Albakr A, Issawi W, Al-Bar M, Recinos PF, Alsaleh S, Ajlan A.
Endoscopic transnasal resection of optic pathway pilocytic astrocytoma.
Childs Nerv Syst. [2018 Oct 18]. 2019;35(1):73-81. Doi 10.1007/s00381-018-3994-4. _




Hidalgo ET, McQuinn MW, Wisoff JH.
Regression after subtotal resection of an optic pathway glioma in an adult without adjuvant therapy: case report.
J Neurosurg. [2018 Jun 1]. 2018;1-4. Doi 10.3171/2017.12.JNS172188. _




Menon SG, Raju VNJ, Bhandary SV, Addoor KR.
Recurrent Optic Nerve Pilocytic Astrocytoma: A Rare Case.
J Clin Diagn Res. [2017 May 1]. 2017;11(5):ND03-ND04. Doi 10.7860/JCDR/2017/26991.9824. _



SKELETAL DISSEMINATION


.

Konar SK, Nandeesh BN, Sandhya M, Chandana N, Devi BI, Bhat DI.
Pilocytic astrocytoma with spontaneous malignant transformation with intracranial and skeletal dissemination: case report and review of the literature.
Br J Neurosurg. [2018 May 10]. 2018;1-4. Doi 10.1080/02688697.2018.1472214. _



SPINAL METASTASIS



Munshey A, Moore J, Maclean C, Longano A, Goldschlager T.
Cranial pilocytic astrocytoma with spinal drop metastasis in an adult: case report and literature review.
World Neurosurg. [2016 Aug 12]. 2017;98:883.e7-883.e12. Doi 10.1016/j.wneu.2016.08.013. _



THALAMIC PILOCYTIC ASTROCYTOMA



Konar SK, Shukla D, Nandeesh BN, Prabhuraj AR, Devi BI.
Surgical Management and Outcome of a Bilateral Thalamic Pilocytic Astrocytoma: Case Report and Review of the Literature.
Pediatr Neurosurg. [2019 Jan 24]. 2019;54(2):139-142. Doi 10.1159/000495990. _



Ethiopathogenesis





Prayson RA.
IDH-1 polymorphisms in pilocytic astrocytomas.
Ann Diagn Pathol. [2019 Oct 23]. 2019;43:151411. Doi 10.1016/j.anndiagpath.2019.151411. _



Management



Tjota MY, Pytel P.
Educational Case: Pilocytic Astrocytoma With Atypical Features.
Acad Pathol. 2020 Mar 30. 2020;7:2374289520912498. Doi 10.1177/2374289520912498. _



Prognosis



Mair MJ, Wöhrer A, Furtner J, Simonovska A, Kiesel B, Oberndorfer S, Ungersböck K, Marosi C, Sahm F, Hainfellner JA, Rössler K, Preusser M, Widhalm G, Berghoff AS.
Clinical characteristics and prognostic factors of adult patients with pilocytic astrocytoma.
J Neurooncol. [2020 Apr 27]. 2020;10.1007/s11060-020-03513-9. Doi 10.1007/s11060-020-03513-9. _




Park JH, Jung N, Kang SJ, Kim HS, Kim E, Lee HJ, Jung HR, Choe M, Shim YJ.
Survival and Prognosis of Patients with Pilocytic Astrocytoma: A Single-Center Study.
Brain Tumor Res Treat. 2019 Oct 29. 2019;7(2):92-97. Doi 10.14791/btrt.2019.7.e36. _




Yecies D, Fisher PG, Cheshier S, Edwards M, Grant G.
Long-term outcomes of primarily metastatic juvenile pilocytic astrocytoma in children.
J Neurosurg Pediatr. [2017 Nov 10]. 2017;1-5. Doi 10.3171/2017.7.PEDS17168. _



GROSS-TOTAL RESECTION



Dodgshun AJ, Maixner WJ, Hansford JR, Sullivan MJ.
Low rates of recurrence and slow progression of pediatric pilocytic astrocytoma after gross-total resection: justification for reducing surveillance imaging.
J Neurosurg Pediatr. [2016 Jan 1]. 2016;17(5):569-72. Doi 10.3171/2015.9.PEDS15449. _



VARIANTS ASSOCIATED WITH TUMOUR LOCATION



Sexton-Oates A, Dodgshun A, Hovestadt V, Jones DT, Ashley DM, Sullivan M, MacGregor D, Saffery R.
Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence.
Mol Oncol. [2017 Apr 7]. 2018;12(8):1219-1232. Doi 10.1002/1878-0261.12062. _



Overall management



Bond KM, Hughes JD, Porter AL, Orina J, Fang S, Parney IF.
Adult pilocytic astrocytoma: An institutional series and systematic literature review for extent of resection and recurrence.
World Neurosurg. [2017 Nov 24]. 2018;110:276-283. Doi 10.1016/j.wneu.2017.11.102. _



Treatment



Adib SD, Schuhmann MU, Hempel JM, Bornemann A, Zamora RE, Tatagiba M.
Surgical management of primary and secondary pilocytic astrocytoma of the cerebellopontine angle (in adults and children) and review of the literature.
Neurosurg Rev. [2020 Apr 15]. 2020;10.1007/s10143-020-01293-4. Doi 10.1007/s10143-020-01293-4. _




Kondyli M, Larouche V, Saint-Martin C, Ellezam B, Pouliot L, Sinnett D, Legault G, Crevier L, Weil A, Farmer JP, Jabado N, Perreault S.
Trametinib for progressive pediatric low-grade gliomas.
J Neurooncol. [2018 Aug 10]. 2018;140(2):435-444. Doi 10.1007/s11060-018-2971-9. _




Miller C, Guillaume D, Dusenbery K, Clark HB, Moertel C.
Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response.
J Neurosurg Pediatr. [2016 Dec 23]. 2017;19(3):319-324. Doi 10.3171/2016.9.PEDS16328. _




Xi G, Li YD, Grahovac G, Rajaram V, Wadhwani N, Pundy T, Mania-Farnell B, James CD, Tomita T.
Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy.
Mol Cancer. 2017 Jan 31. 2017;16(1):21. Doi 10.1186/s12943-017-0593-z. _



Variant: Pilomyxoid astrocytoma




Case reports



Almubarak AO, Ulhaq A, BinDahmash A, Al Shail E.
Spinal Pilomyxoid Astrocytoma.
Pediatr Neurosurg. [2019 Oct 8]. 2019;54(6):399-404. Doi 10.1159/000502615. _




He J, Li X, Zhu W, Li C, Gong J.
Posterior fossa pilomyxoid astrocytoma with spontaneous hemorrhage in pediatric patients.
Childs Nerv Syst. [2017 Jul 24]. 2018 Jan;34(1):149-153. Doi 10.1007/s00381-017-3549-0. _



Subependymal giant cell astrocytoma




Case report


Case report

Barnes A, Wang MM, Feltes J, Ko J, Guzman MA.
Subependymal Giant-cell Astrocytoma Masquerading as Restrictive Eating Disorder and Depression in an Adolescent.
Innov Clin Neurosci. 2020 Jan 1. 2020;17(1-3):10-13. _



Epidemiology



Nguyen HS, Doan NB, Gelsomino M, Shabani S, Awad AJ, Best B, Kaushal M, Mortazavi MM.
Subependymal Giant Cell Astrocytoma: A Surveillance, Epidemiology, and End Results Program-Based Analysis from 2004 to 2013.
World Neurosurg. [2018 Jun 30]. 2018;118:e263-e268. Doi 10.1016/j.wneu.2018.06.169. _



Treatment





Dadey DY, Kamath AA, Leuthardt EC, Smyth MD.
Laser interstitial thermal therapy for subependymal giant cell astrocytoma: technical case report.
Neurosurg Focus. 2016 Oct. 2016;41(4):E9. doi: 10.3171/2016.7.FOCUS16231. _



Pleomorphic xanthoastrocytoma




Case reports




ANAPLASTIC FEATURES



Patibandla MR, Nayak M, Purohit AK, Thotakura AK, Uppin M, Challa S.
Pleomorphic xanthoastrocytoma with anaplastic features: A rare case report and review of literature with reference to current management.
Asian J Neurosurg. [2016 Apr 5]. 2016;11(3):319. Doi 10.4103/1793-5482.144161. _




Rutkowski MJ, Oh T, Niflioglu GG, Safaee M, Tihan T, Parsa AT.
Pleomorphic Xanthoastrocytoma with anaplastic features: a retrospective case series.
World Neurosurg. [2016 Jul 28]. 2016;95:368-374. Doi 10.1016/j.wneu.2016.07.068. _



ADULT CEREBELLUM



Chen AS, Paldor I, Tsui AE, Yuen TI.
Pilomyxoid astrocytoma in the adult cerebellum.
J Clin Neurosci. [2016 Jan 14]. 2016;27:170-3. Doi 10.1016/j.jocn.2015.11.008. _



PERSONALIZED MEDICINE


*

Piña Y, Fusco MJ, Macaulay RJ, Walko CM, Peguero E, Evernden BR, Smalley KS, Forsyth P.
Using personalized medicine in gliomas: a genomic approach to diagnosis and overcoming treatment resistance in a case with pleomorphic xanthoastrocytoma.
J Neurol. [2019 Nov 21]. 2020;267(3):783-790. Doi 10.1007/s00415-019-09575-8. _



Prognosis





Tonse R, Gupta T, Epari S, Shastri JG, Gurav M, Bano N, Jalali R.
Impact of WHO 2016 update of brain tumor classification, molecular markers and clinical outcomes in pleomorphic xanthoastrocytoma.
J Neurooncol. [2017 Nov 16]. 2018 Jan;136(2):343-350. Doi 10.1007/s11060-017-2658-7. _



Treatment



Finch EA, Elton SW, Huang BY, Trembath DG, Blatt J.
Long-term Efficacy of Single-agent Vemurafenib for Pleomorphic Xanthoastrocytoma.
J Pediatr Hematol Oncol. [2018 Dec 27]. Doi 10.1097/MPH.0000000000001395. _