[Brainlife] Newsletter, Vol.3 No.15, 20 May 2004

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BRAINLIFE NEWSLETTER

Volume 3, Number 15 - 20 May 2004	Volume 3 Archive


Contents

	Epidemiology & Risk Factors
	Etiology & Pathogenesis
	Overall Management
	Prognosis & Outcome
	Treatment


Epidemiology & Risk Factors

	Jill S. Barnholtz-Sloan, Andrew E. Sloan, Faith G. Davis, Fawn D. Vigneau, Ping Lai, Raymond E. Sawaya Incidence proportions of brain metastases in the Metropolitan Detroit Cancer Surveillance System (MDCSS) 1973-2001 Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5240.
	Herbert H. Engelhard III, Kimberly R. Porter, Andrew K. Stewart, Jeffrey J. Olson Overview of the results of the Commission on Cancer's Central Nervous System (CNS) Tumor Patient Care Evaluation Study Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5242.
	Herbert H. Engelhard III, Kimberly R. Porter, Andrew K. Stewart, Jeffrey J. Olson Distribution of genetic predisposition and past history of cancer in 9672 patients with primary central nervous system tumors Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5243.

Etiology & Pathogenesis

	Teralee Burton, Priti Baijal, Shunzhen Zhang, Elizabeth Henson, Spencer B. Gibson, David D. Eisenstat The cell death gene BNIP3 is mutated in astrocytic tumors Proceedings of the AACR, Volume 45, March 2004. Abstract Number: 5236
	Piergiorgio Modena, Joris Weltman, Elena Lualdi, Federica Facchinetti, Irene Janssen, Lisenka Wissers, Felice Giangaspero, Marco Forni, Gaetano Finocchiaro, Riccardo Riccardi, Franca Fossati Bellani, Maura Massimino, Eric Schoenmakers, Gabriella Sozzi Genome-wide analysis of genomic imbalances in intracranial ependymomas Proceedings of the AACR, Volume 45, March 2004. Abstract Number: 1671

Overall Management

	Markus Bredel, Claudia Bredel, Hannes Vogel, Griffith Harsh IV, Branimir I. Sikic Multiple displacement amplification-based comprehensive genome amplification in fresh-frozen and formalin-fixed/paraffin-embedded clinical brain tumor samples Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5238.

Prognosis & Outcome

	Yi-Hong Zhou, Kenneth R. Hess, W. K. Alfred Yung Prognostic model for glioma patients Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 1078.

Treatment

	Lorena Bissola, Marica Eoli, Francesca Menghi, Bianca Pollo, Antonio Silvani, Giovanni Broggi, Amerigo Boiardi, Gaetano Finocchiaro MGMT promoter hypermethylation is more frequent in secondary glioblastomas and is independent from other prognostic factors Proceedings of the AACR, Volume 45, March 2004. Abstract Number: 1077
	Michael S. Bobola, Richard Ellenbogen, Ryan Goff, John Silber Ablation of O⁶-methylguanine-DNA methyltransferase with O⁶-benzylguanine reduces the resistance of pediatric primary brain tumor cell lines to temozolomide and BCNU Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 2143.
	Ulrich Bogdahn, Peter Hau, Alexander Brawanski, Juergen Schlaier, Maximilian Mehdorn, Arya Nabavi, Gabriele Wurm, Josef Pichler, Mechthild Kunst, Michael Goldbrunner, Gerhard Stauder, Gerhard Stauder, Karl-Hermann Schlingensiepen Tgf-beta2 suppression by the antisense oligonucleotide ap 12009 as therapy for high-grade glioma: Safety and efficacy results of phase i/ii clinical studies Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5239.
	Arabinda Das, Kunal D. Patel, Marc S. Weinberg, Sunil J. Patel, Naren L. Banik, Swapan K. Ray Modulatory effect of dexamethasone on temozolomide induced apoptosis in human glioblastoma U87MG cells Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 554.
	Takao Kanzawa, Hideaki Ito, Yasuko Kondo, Seiji Kondo Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 579.
	Hans-Peter Kiem, Tobias Neff, Brian C. Beard, Laura J. Peterson, Bobbie M. Thomasson, Jess Thompson Gene Therapy To Protect Hematopoietic Cells From Cytotoxic Chemotherapy In A Clinically Relevant Large Animal Model Proceedings of the AACR, Volume 45, March 2004, Abstract Number: LB-284.
	Hidemitsu Nakagawa Intrathecal or intracavitary administration of sodium butyrate to treat neoplastic meningitis and malignant glioma Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 5241.
	David A. Reardon, G. Akabani, J. Dowell, Allan Friedman, Henry Friedman, James Herndon, Roger McLendon, Jennifer Quinn, Jeremy Rich, James Vredenburgh, Kara Penne, John Sampson, Timothy Shafman, Terrance Wong, R. Coleman, Michael Zalutsky, Darell Bigner Results of a phase II trial with iodine 131-labeled murine antitenascin monoclonal antibody 81c6 (m81c6) via surgically created resection cavities in the treatment of patients with recurrent malignant brain tumors Proceedings of the AACR, Volume 45, March 2004. Abstract Number: 5237
	Lucio Tentori, Carlo Leonetti, Marco Scarsella, Weizheng Xu, David C. Calvin, Lisa Morgan, Zhaocheng Tang, Krystyna M. Wozniak, Christina Alemu, Randall Hoover, Rena G. Lapidus, Gabriella Zupi, Jie Zhang, Grazia Graziani Oral administration of the PARP-1 inhibitor GPI 15427 increases the anti-tumor activity of temozolomide against melanoma growing at the CNS site Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 2007.
	Meg Verrees, Lili Liu, Stanton L. Gerson Interruption of base excision repair selectively enhances temozolamide and 1,3-bis(2-chloroethyl)-nitrosurea cytotoxicity in treatment of adult human malignant glioma cell lines Proceedings of the AACR, Volume 45, March 2004, Abstract Number: 1548.

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