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BRAINLIFE NEWSLETTER
Volume 3, Number 20 - 19 June 2004

Volume 3
Archive


Contents


Etiology & Pathogenesis
Overall Management
Prognosis & Outcome
Treatment

Etiology & Pathogenesis


E. Franceschi, G. Cavallo, A. Paioli, L. Scopece, R. Degli Esposti, E. Leonardi, F. Spagnolli, A. M. Cremonini, A. Pession, L. Crino
Evaluation of 1p and 19q chromosomal alterations in oligodendroglial neoplasms using microdissection and microsatellite analysis technique and correlations with response to chemotherapy
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1568 

H. Kobayashi, N. Ishii, J. Ikeda, Y. Sawamura, Y. Iwasaki
Methylation profiling of the DNA repair genes in glioblastoma multiforme and its clinical relevance
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1572 

K. D. Weaver, S. Grossman, J. Herman
Methylated tumor-specific DNA as a plasma biomarker in patients with glioma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1527 


Overall Management


C. Garufi, B. Vanni, C. Francesca, C. Campanella, A. M. Aschelter, E. Bria, C. Nistic̣, F. Cuppone, I. Sperduti, E. Terzoli
Evidence for an aggressive biological behaviour of brain metastases in advanced colorectal cancer patients
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1579 

D. R. Gomez, B. T. Missett, W. M. Wara, D. A. Larson, P. K. Sneed, M. D. Prados, S. M. Chang, M. S. Berger, N. Gupta, D. A. Haas-Kogan;
High failure rate in spinal ependymomas with long-term follow-up
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1528 

L. Kutikova, L. Bowman, S. Chang, S. Long
How costly is brain cancer? Healthcare services use and costs from across the US
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1559 


Prognosis & Outcome


U. K. Bartels, C. Hawkins, J. Ma, A. Ray, P. Dirks, J. Rutka, E. Bouffet
Microvessel density predicts behavior in pediatric optic pathway/hypothalamic gliomas
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1556 

J. C. Buckner, K. D. Aldape, K. Ballman, B. W. Scheithauer, P. C. Burger, C. Giannini, P. L. Schaefer, R. B. Jenkins, C. D. James
Immunohistochemical detection of EGFRvIII and prognostic significance in patients with malignant glioma enrolled in NCCTG clinical trials
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1508 

C. Ford, W. Seiferheld, A. K. Choucair, J. Hansen, B. Dabbas, C. Schultz, A. Schulsinger, M. Mehta, W. Curran
Evaluation of expression of DNA repair molecules as a prognostic factor for long-term survivors with glioblastoma multiforme (GBM) treated on RTOG protocols with irradiation and nitrosoureas
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1509 

C. Marosi, M. Hassler, J. A. Hainfellner, M. Van Trotsenburg, M. Preusser, P. Birner, J. Berger
Microvessel density in progressive meningiomas and its influence on time to tumour recurrence
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1563 

S. Soyuer, E. L. Chang, U. Selek, M. H. Maor, F. Demonte
Operable benign meningioma patients appear to have expected survival that is equivalent to a normal United States population
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1543 


Treatment


H. Aoyama, H. Shirato, K. Nakagawa, M. Tago
Interim report of the JROSG99-1 multi-institutional randomized trial, comparing radiosurgery alone vs. radiosurgery plus whole brain irradiation for 1-4 brain metastases
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1506 

M. T. Carpenter, J. C. Flickinger, M. A. Quader, C. E. Miles
Improvements in technique for whole-brain irradiation
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1539

G. Dresemann
Imatinib (STI571) plus hydroxyurea: Safety and efficacy in pre-treated, progressive glioblastoma multiforme (GBM) patients (pts)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1550

E. Galanis, J. C. Buckner, M. Maurer, K. Ballman, M. Hidalgo, J. I. Kreisberg, J. Boni, C. D. D. James, R. B. Jenkins, D. J. Walsh
NCCTG phase II trial of CCI-779 in recurrent glioblastoma multiforme (GBM)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1503

A. Katz, C. H. Barrios, R. Abramoff, S. D. Simon, J. Tabacof, R. C. Gansl 
Imatinib (STI 571) is active in patients (PTS) with high-grade gliomas progressing on standard therapy
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1542 

R. V. Larocca, A. Cervera, J. B. Hargis, S. D. Glisson, G. H. Goldsmith, M. A. M. Laureano, B. Foreman
High-dose (HD) irinotecan in patients with recurrent unresectable high-grade gliomas on glucoronidation-enhancing anticonvulsants (GEACs): A phase I/II study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1578 

F. S. Lieberman, T. Cloughesy, H. Fine, J. Kuhn, K. Lamborn, M. Malkin, H. I. Robbins, W. A. Yung, P. Wen, M. Prados
NABTC phase I/II trial of ZD-1839 for recurrent malignant gliomas and unresectable meningiomas
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1510 

A. Narayana, J. Yamada, M. Hunt, P. Shah, P. Gutin, S. A. Leibel
Intensity modulated radiotherapy in high grade gliomas: Clinical and dosimetric results
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1532

P. Z. New, S. Grossman, T. Mikkelsen, T. Batchelor, S. Phuphanich, K. Carson, J. Fisher, M. Craig, P. Cagnoni
Evaluation of safety and tolerance of escalating doses of RSR13 administered with a fixed dose of BCNU every six weeks in patients with recurrent malignant glioma: Results of the phase I NABTT 9806 clinical trial
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1533

A. Pace, A. Pompili, M. Maschio, E. Galie', S. Telera, B. Jandolo, E. Occhipinti, C. M. Carapella
PCV and/or TMZ chemotherapy in 255 gliomas. Analysis of the clinical experience from a neuro-oncology data-base
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1538

E. Raymond, A. Brandes, A. Van Oosterom, C. Dittrich, P. Fumoleau, B. Coudert, C. Twelves, C. De Balincourt, D. Lacombe, M. Van Den Bent
Multicentre phase II study of imatinib mesylate in patients with recurrent glioblastoma: An EORTC: NDDG/BTG Intergroup Study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1501

H. Schulz, H. Pels, U. Schlegel, U. Zeelen, U. Germing, A. Engert
Intraventricular application of rituximab as a treatment option in patients with CNS lymphoma and leptomeningeal disease
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1521

E. Thiel, K. Jahnke, T. Wagner, N. E. Bechrakis, S. E. Coupland, A. Schmittel, L. Fischer, M. H. Foerster, A. Korfel
Ifosfamide for intraocular lymphoma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1520 

W. Wick, J. P. Steinbach, J. Schuth, J. Dichgans, M. Bamberg, M. Weller
One week on/one week off regimen of temozolomide for recurrent glioblastoma: A phase II study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1536 (Clinical Study)

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