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BRAINLIFE NEWSLETTER
Volume 3, Number 21 - 23 June 2004

Volume 3
Archive


Contents


Etiology & Pathogenesis
Overall Management
Prognosis & Outcome
Psychosocial Aspects
Treatment

Etiology & Pathogenesis


D. S. Keith, D. T. Blumenthal, L. A. Cannon-Albright
The familiality of primary brain tumors as studied in the Utah Population Database (UPDB)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1526 


Overall Management


G. M. Videtic, D. J. Adelstein, T. Mekhail, T. W. Rice, G. H. J. Stevens, S.-Y. Lee, J. H. Suh
Validation of the RTOG recursive partitioning analysis (RPA) classification for small cell lung cancer-only brain metastases: A single institution experience
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1557


Prognosis & Outcome


M. Frenay, A. Ramaioli, D. Fontaine, V. Bourg, F. Vandenbos, C. Lebrun
Prognostic factors of oligodendrogliomas
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1560 

B. E. Lally, J. M. Colasanto, J. P. S. Knisely
The prognostic effect of hemoglobin levels on survival for patients with high-grade gliomas
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1565 


Psychosocial Aspects


P. D. Brown, K. V. Ballman, T. A. Rummans, M. J. Maurer, J. A. Sloan, B. F. Boeve, R. M. Arusell, M. M. Clark, J. C. Buckner
Prospective NCCTG quality of life (QOL) study in adult newly diagnosed high-grade gliomas (HGG)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1524 


Treatment


W. O. Arafat, D. Rein, D. Buchsbaum, D. Curiel, Z. Zhu
Survivin as a novel radiation/CIS platinum/tumor specific promoter for conditional oncolytic viral therapy
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1535 

M. A. Badruddoja, D. A. Reardon, G. Akabani, A. H. Friedman, H. S. Friedman, J. N. Rich, J. A. Quinn, K. Penne, J. J. Vredenburgh, D. D. Bigner
Phase II trial of iodine 131-labeled murine anti-tenascin monoclonal anti-body 81C6 (M81C6) via surgically created resection cavity in the treatment of patients with recurrent malignant brain tumors
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1569 

T. Batchelor, S. Grossman, K. Carson, J. Fisher
Updated results from NABTT CNS consortium studies in primary CNS lymphoma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1519

U. Bogdahn, P. Hau, A. Brawanski, J. Schlaier, M. Mehdorn, G. Wurm, J. Pichler, M. Kunst, G. Stauder, K.-H. Schlingensiepen
Specific therapy for high-grade glioma by convection-enhanced delivery of the TGF-β2 specific antisense oligonucleotide AP 12009
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1514 

A. A. Brandes, A. Tosoni, M. Reni, F. Valduga, U. Basso, S. Lonardi, L. M. Pasetto, V. Blatt, S. Monfardini, M. Ermani
Second line BCNU plus CPT-11 chemotherapy in recurrent glioblastoma (GBM): Phase II study of GICNO (Italian Neuro-Oncology Group)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1516 

S. Brem, S. A. Grossman, K. A. Carson, P. New, S. Phuphanich, J. B. Alavi, T. Mikkelsen, R. Priet
Phase II trial of copper depletion as angiosuppressive treatment in newly diagnosed Glioblastoma Multiforme: Final report
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1530 

M. Caraglia, R. Addeo, R. Costanzo, L. Montella, V. Faiola, E. Capasso, S. Del Prete
Pegylated liposomal doxorubicin plus temozolamide in the salvage treatment of brain metastases: The update
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1576 

S. E. Combs, S. Gutwein, D. Schulz-Ertner, M. Van Kampen, C. Thilmann, M. M. Wannenmacher, J. Debus
Temozolomide combined with radiation as first-line treatment in primary glioblastoma multiforme: Phase I/II-study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1531 

A. Desjardins, J. A. Quinn, D. A. Reardon, J. N. Rich, J. J. Vredenburgh, C. Efird, H. S. Friedman
Phase II study of thalidomide and daily cyclophosphamide for adults with malignant glioma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1554 

A. I. Freeman, J. M. Gomori, E. Linetsky, Z. Zakay-Rones, A. Panet, E. Libson, C. S. Irving, E. Galun, T. Siegal
Phase I/II trial of intravenous OV001 oncolytic virus in resistant glioblastoma multiforme (GBM)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1515 

M. W. Kieran, R. Packer, J. Boyett, M. Sugrue, L. Kun, Pediatric Brain Tumor Consortium (PBTC)
Phase I trial of the oral farnesyl protein transferase inhibitor lonafarnib (SCH66336): A Pediatric Brain Tumor Consortium (PBTC) study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1517 

R. R. Maņon, A. Oneill, M. Mehta, J. Knisely, M. Werner-Wasik, H. Lazarus, H. Wagner, M. Gilbert
Phase II trial of radiosurgery (RS) for 1 to 3 newly diagnosed brain metastases from renal cell, melanoma, and sarcoma: An Eastern Cooperative Oncology Group Study (E6397)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1507 

P. L. Moots, A. O'Neill, G. R. Barger, M. P. Mehta, M. R. Gilbert
Toxicities associated with chemotherapy followed by craniospinal radiation for adults with poor-risk medulloblastoma/PNET and disseminated ependymoma; a preliminary report of ECOG 4397
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1573 

B. Neyns, E. Everaert, E. Joosens, T. Strauven, F. Branle, J. Menten
Temozolomide for the treatment of recurrent glioma: Results of a compassionate use program in Belgium
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1541 

C. Nieder, N. Wiedenmann, S. Stark, A. L. Grosu
Phase II trial of functional imaging-optimized stereotactic fractionated radiotherapy plus temozolomide for recurrent high-grade glioma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1552 

S. Pannullo, S. Hariharan, J. Serventi, R. Hayes, C. Balmaceda, J. Burton
Phase I/II trial of a twice-daily regimen of temozolomide and celecoxib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1549 

M. Prados, W. Yung, P. Wen, L. Junck, K. Fink, T. Cloughesy, I. Robins, S. Chang, J. Kuhn
Phase I study of ZD1839 plus temozolomide in patients with malignant glioma. A study of the North American Brain Tumor Consortium
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1504 

J. M. Simon, G. Noel, K. Hoang-Xuan, A. F. Carpentier, K. Mokhtari, S. Racadot, F. Baillet, J. J. Mazeron
Radiotherapy and concomitant weekly carboplatin and daily etoposide for patients with inoperable biopsy proven glioblastoma multiforme
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1544 

M. A. Spear, A. Mirmiran, E. McClay
Phase I/II trial of IV topotecan (TOPO) in combination with whole brain radiation therapy (WBXRT)
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1553 

S. Tafuto, R. Guarrasi, A. Tortoriello, F. Buzzi, P. Muto, R. Formato, P. Comella, P. De Rosa, R. V. Iaffaioli, S. Quattrin
Temozolomide (TMZ) and lomustine (CCNU) in high grade glioma (HGG) patients: Phase I study
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1577 

J. H. Uhm, K. V. Ballman, C. Giannini, J. C. Krauss, J. C. Buckner, D. James, B. W. Scheithauer, J. R. O'Fallon, K. A. Jaeckle
Phase II study of ZD1839 in patients with newly diagnosed grade 4 astrocytoma
40th ASCO Annual Meeting. New Orleans, LA. June 5-8, 2004. Abstract No.1505 

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