[Brainlife] Newsletter, Vol.3 No.40, 13 Dec 2004

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BRAINLIFE NEWSLETTER

Volume 3, Number 40 - 13 December 2004	Volume 3 Archive


	Special Issue • Anti-angiogenic drugs and glioma invasiveness

Brain Tumors
	Zagzag D, Friedlander DR, Margolis B, Grumet M, Semenza GL, Zhong H, Simons JW, Holash J, Wiegand SJ, Yancopoulos GD Molecular events implicated in brain tumor angiogenesis and invasion Pediatr Neurosurg. 2000 Jul;33(1):49-55.

Glioblastoma

	Philip Kunkel, Ulrike Ulbricht, Peter Bohlen, Marc A. Brockmann, Regina Fillbrandt, Dimitrios Stavrou, Manfred Westphal and Katrin Lamszus Inhibition of Glioma Angiogenesis and Growth in Vivo by Systemic Treatment with a Monoclonal Antibody against Vascular Endothelial Growth Factor Receptor-2 Cancer Research 61, 6624-6628, September 15, 2001.
	Rubenstein JL, Kim J, Ozawa T, Zhang M, Westphal M, Deen DF, Shuman MA Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption Neoplasia. 2000 Jul-Aug;2(4):306-14.

Gliomas

	Tim Demuth, Michael E. Berens Molecular Mechanisms of Glioma Cell Migration and Invasion J Neurooncol, 70(2):217-228, November 2004.
	J. Holash, P. C. Maisonpierre, D. Compton, P. Boland, C. R. Alexander, D. Zagzag, G. D. Yancopoulos, S. J. Wiegand Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF Science, Vol 284, Issue 5422, 1994-1998 , 18 June 1999.
	Lamszus K, Kunkel P, Westphal M Acta Neurochir Suppl. 2003;88:169-77.
	Peoch M, Farion R, Hiou A, Le Bas JF, Pasquier B, Remy C Immunohistochemical study of VEGF, angiopoietin 2 and their receptors in the neovascularization following microinjection of C6 glioma cells into rat brain Anticancer Res. 2002 Jul-Aug;22(4):2147-51.
	Zagzag D, Amirnovin R, Greco MA, Yee H, Holash J, Wiegand SJ, Zabski S, Yancopoulos GD, Grumet M Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis Lab Invest. 2000 Jun;80(6):837-49.

Neuroblastoma

	Eugene S. Kim, Anna Serur, Jianzhong Huang, Christina A. Manley, Kimberly W. McCrudden, Jason S. Frischer, Samuel Z. Soffer, Laurence Ring, Tamara New, Stephanie Zabski, John S. Rudge, Jocelyn Holash, George D. Yancopoulos, Jessica J. Kandel and Darrell J. Yamashiro Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma PNAS, August 20, 2002; Vol. 99, No. 17, 11399-11404.

Tumors

	Belo AV, Barcelos LS, Teixeir MM, Ferreira MA, Andrade SP. Differential effects of antiangiogenic compounds in neovascularization, leukocyte recruitment, VEGF production, and tumor growth in mice. Cancer Invest. 2004;22(5):723-9.
	Holash J, Wiegand SJ, Yancopoulos GD New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF Oncogene. 1999 Sep 20;18(38):5356-62.

Wilms Tumor

	Huang J, Frischer JS, New T, Kim ES, Serur A, Lee A, Kadenhe-Chiwishe A, Pollyea DA, Yokoi A, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ TNP-470 promotes initial vascular sprouting in xenograft tumors Mol Cancer Ther. 2004 Mar;3(3):335-43.