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| BRAINLIFE NEWSLETTER | |
Volume 5, Supplement 8 - 31
August 2006 |
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Basic Science |
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David Terraso
Scientists Uncover Critical Step in DNA Mutation Georgia Institute of Technology, News Releases, August 23, 2006 
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Robert N. Barnett, Angelo Bongiorno,
Charles L. Cleveland, Abraham Joy, Uzi Landman, and Gary B. Schuster
Oxidative Damage to DNA: Counterion-Assisted Addition of Water to Ionized DNA J. Am. Chem. Soc.,128 (33), 10795 -10800, 2006. DOI: 10.1021/ja061795y, Web Release Date: 28 July 2006 |
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Heidi Hardman
With few factors, adult cells take on character of embryonic stem cells EurekAlert!, 10 August 2006 News
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Kazutoshi Takahashi
and Shinya Yamanaka
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Cell, Article in Press, Corrected Proof, doi:10.1016/j.cell.2006.07.024, Available online 10 August 2006 |
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Brain Tumors |
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Reuters Health
Functional MRI allows more aggressive brain tumor treatment OncoLink, August 30, 2006 News
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Heather Babiar
Preoperative brain mapping alters tumor surgery EurekAlert!, 29 August 2006 News
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Jeffrey R. Petrella, MD, Lubdha M. Shah,
MD, Katy M. Harris, BS, Allen H. Friedman, MD, Timothy M. George, MD, John H.
Sampson, MD, PhD, Joseph S. Pekala, MD and James T. Voyvodic, PhD
Preoperative Functional MR Imaging Localization of Language and Motor Areas: Effect on Therapeutic Decision Making in Patients with Potentially Resectable Brain Tumors Radiology 2006 (September) 240: 793-802. Published online before print July 20 2006, 10.1148/radiol.2403051153 |
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Leslie Orr Study links lead exposure to brain cancer in adults EurekAlert!, 28 August 2006 News
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Edwin
van Wijngaarden,
Mustafa Dosemeci
Brain cancer mortality and potential occupational exposure to lead: Findings from the National Longitudinal Mortality Study, 1979-1989 International Journal of Cancer, Volume 119, Issue 5, 1 September 2006, Pages 1136-1144; Published Online: 28 Mar 2006 |
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Autocrine/Paracrine Platelet-Derived Growth Factor Regulates Proliferation of Neural Progenitor Cells Cancer Research 66, 8042-8048, August 15, 2006 |
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NCI Cancer Bulletin
Loss of Cellular Motor Protein Contributes to Tumor Formation NCI Cancer Bulletin, August 8, 2006, Volume 3, Number 32
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Manjari Mazumdar, Ji-Hyeon Lee, Kundan
Sengupta, Thomas Ried, Sushil Rane and Tom Misteli Tumor Formation via Loss of a Molecular Motor Protein Current Biology, Volume 16, Issue 15, 8 August 2006, Pages 1559-1564, doi:10.1016/j.cub.2006.06.029, Available online 7 August 2006 |
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Megan Rauscher
Paternal heat exposure may raise risk of childhood brain tumor OncoLink, 3 August 2006
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Parental Heat Exposure and Risk of Childhood Brain Tumor: A Children's Oncology Group Study American Journal of Epidemiology 2006 (1 August) 164(3):222-231; doi:10.1093/aje/kwj174, Originally published online on June 14, 2006 |
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Health Status Measurements at Diagnosis As Predictors of Survival Among Adults With Brain Tumors Journal of Clinical Oncology, Vol 24, No 22 (August 1), 2006: pp. 3636-3643, DOI: 10.1200/JCO.2006.06.0137 |
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| Treatment > Immunotherapy / Stem Cells | |
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Featured Article |
Patrizia Tunici, Ph.D., Dwain Irvin,
Ph.D., M.P.H., Gentao Liu, Ph.D., Xiangpeng Yuan, Ph.D., Zeng Zhaohui,
Ph.D., Hiushan Ng, M.S., and John S. Yu, M.D.
Brain tumor stem cells: new targets for clinical treatments? Neurosurg Focus 20 (4):E27, April 2006 
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/ BrainLife |
Full Text |
Reprint
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| Etiology and Pathogenesis > Stem Cells | |
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Featured Article |
Münevver Büyükpamukçu, MD;
Ali Varan, MD; Nalan Yazici, MD; Nejat Akalan, MD; Figen Söylemezoglu, MD;
Faruk Zorlu, MD; Canan Akyüz, MD; M. Tezer Kutluk, MD, PhD
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Cancer Research |
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James E. Kloeppel
Synthetic molecule causes cancer cells to self-destruct EurekAlert!, 27 August 2006 News
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| Karson S Putt,
Grace W Chen, Jennifer M Pearson, Joseph S Sandhorst, Martin S Hoagland,
Jung-Taek Kwon, Soon-Kyung Hwang, Hua Jin, Mona I Churchwell, Myung-Haing
Cho, Daniel R Doerge, William G Helferich and Paul J Hergenrother
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy Nature Chemical Biology, Published online: 27 August 2006; doi:10.1038/nchembio814 |
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Dr. André Skirtach
Microcapsules Open in Tumour Cells Max Planck Society, Press Release, 23 August 2006
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| Andre G.
Skirtach, Dr., Almudena Muñoz Javier, Oliver Kreft, Dr., Karen
Köhler,
Alicia Piera Alberola, Helmuth Möhwald, Prof. Dr., Wolfgang J. Parak,
Dr., Gleb B. Sukhorukov, Prof. Dr. Laser-Induced Release of Encapsulated Materials inside Living Cells Angewandte Chemie International Edition, Volume 45, Issue 28 , Pages 4612 - 4617 (10 July, 2006), DOI: 10.1002/anie.200504599, Published Online: 22 Jun 2006 |
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James Newton
'Signature' of chromosome instability predicts cancer outcomes EurekAlert!, 20 August 2006
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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers Nature Genetics, Advance online publication, Published online: 20 August 2006; doi:10.1038/ng1861 |
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Reuters Health
Findings shed light on anti-angiogenic effect of p53 OncoLink, 18 August 2006
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p53-Mediated Inhibition of Angiogenesis Through Up-Regulation of a Collagen Prolyl Hydroxylase Science, 18 August 2006:Vol. 313. no. 5789, pp. 968 - 971, DOI: 10.1126/science.1126391 |
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NCI Cancer Bulletin
How Some Tumors Evade Attack by Immune Cells NCI Cancer Bulletin, August 15, 2006, Volume 3, Number 33
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Akio Ohta, Elieser Gorelik,
Simon J. Prasad, Franca Ronchese, Dmitriy Lukashev, Michael K. K. Wong,
Xiaojun Huang, Sheila Caldwell, Kebin Liu, Patrick Smith, Jiang-Fan Chen,
Edwin K. Jackson, Sergey Apasov, Scott Abrams, and Michail Sitkovsky
A2A adenosine receptor protects tumors from antitumor T cells Proc. Natl. Acad. Sci. USA, DOI: 10.1073/pnas.0605251103, Published online before print August 17, 2006 |
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Heidi Hardman
Novel pathway identifies rapamycin as tumor angiogenesis inhibitor EurekAlert!, 14 August 2006
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Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin Cancer Cell, Vol 10, 159-170, August 2006. Published: August 14, 2006. |
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Gliomas |
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Darrell E. Ward
Study shows how cancer drug aids anti-cancer virus Ohio State University News, 29 August 2006 News
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Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses PNAS, August 22, 2006, vol. 103, no. 34, 12873-12878; Published online before print August 14, 2006, 10.1073/pnas.0605496103 |
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Cyclophosphamide Allows for In vivo Dose Reduction of a Potent Oncolytic Virus Cancer Research 65, 11255-11258, December 15, 2005 |
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An Oncolytic HSV-1 Mutant Expressing ICP34.5 under Control of a Nestin Promoter Increases Survival of Animals even when Symptomatic from a Brain Tumor
Cancer Research 65, 2832-2839, April 1, 2005 |
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Will Boggs, MD
Stem cell-like glioma cells promote tumor angiogenesis OncoLink, 23 August 2006
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Warren Froelich
Cancer stem cells spur glioma angiogenesis, could hold key to brain tumor therapy EurekAlert!, 15 August 2006
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Stem Celllike Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor Cancer Research 66, 7843-7848, August 15, 2006 |
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NCI Cancer Bulletin
Synthetic Scorpion Venom Targets Brain Tumor Cells NCI Cancer Bulletin, August 8, 2006, Volume 3, Number 32
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Phase I Single-Dose Study of Intracavitary-Administered Iodine-131-TM-601 in Adults With Recurrent High-Grade Glioma Journal of Clinical Oncology, Vol 24, No 22 (August 1), 2006: pp. 3644-3650, DOI: 10.1200/JCO.2005.05.4569 |
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Reuters Health
L-type amino acid transporter 1 plays key role in human gliomas OncoLink, 7 August 2006
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Hiroshi
Nawashiro,
Naoki Otani, Nariyoshi Shinomiya, Shinji Fukui, Hidetoshi Ooigawa, Katsuji
Shima, Hirotaka Matsuo, Yoshikatsu Kanai, Hitoshi Endou
L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors International Journal of Cancer, Volume 119, Issue 3, Pages 484 - 492, DOI: 10.1002/ijc.21866, Published Online: 22 Feb 2006 |
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Phase II Trial of Tipifarnib in Patients With Recurrent Malignant Glioma Either Receiving or Not Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study Journal of Clinical Oncology, Vol 24, No 22 (August 1), 2006: pp. 3651-3656, DOI: 10.1200/JCO.2006.06.2323 |
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Glioblastoma |
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Featured Article
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Ben
A. Williams,
PhD |
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Featured Article
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Paolo Ferroli, M.D.; Morgan Broggi,
M.D.; Angelo Franzini, M.D.; Elio Maccagnano, M.D.; Massimo Lamperti,
M.D.; Amerigo Boiardi, M.D.; Giovanni Broggi, M.D.
Surgifoam and Mitoxantrone in the Glioblastoma Multiforme Postresection Cavity: The First Step of Locoregional Chemotherapy through an Ad Hoc-placed Catheter: Technical Note Neurosurgery. 59(2):E433-E434, August 2006 |
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Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13α2 receptor PNAS, April 4, 2006, vol. 103, no. 14. 5508-5513; Published online before print March 22, 2006, 10.1073/pnas.0601258103 |
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Characterization of a Recombinant Herpes Simplex Virus 1 Designed To Enter Cells via the IL13Rα2 Receptor of Malignant Glioma Cells
Journal of Virology, May 2005, p. 5272-5277, Vol. 79, No. 9;
doi:10.1128/JVI.79.9.5272-5277.2005
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Neuroblastoma |
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Reuters Health
Bortezomib effective against neuroblastoma in animal studies OncoLink, 29 August 2006 News
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Effect of Bortezomib on Human Neuroblastoma Cell Growth, Apoptosis, and Angiogenesis Journal of the National Cancer Institute, Vol. 98, No. 16, 1142-1157, August 16, 2006; DOI: 10.1093/jnci/djj309 |