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| BRAINLIFE NEWSLETTER | |
Volume 5, Supplement 9bis - 30 September 2006 |
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Basic Science |
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Christine Leon
Two-faced protein can stop metastasis or promote it, researchers say EurekAlert!, 18 September 2006 
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| Etiology and Pathogenesis > Metastasis Biology | |
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p120 catenin is essential for mesenchymal cadherin–mediated regulation of cell motility and invasiveness J Cell Biol. 2006 Sep 25;174(7):1087-96. Epub 2006 Sep 18. 
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Rebecca Levine
Newly discovered behavior in cancer cells signals dangerous metastasis EurekAlert!, 15 September 2006
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| Etiology and Pathogenesis > Metastasis Biology | |
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Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14116-21. Epub 2006 Sep 8.
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Warren Froelich
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs EurekAlert!, 15 September 2006
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Results were presented at the first international meeting on Molecular Diagnostics in Cancer Therapeutic Development, organized by the American Association for Cancer Research |
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Heidi Hardman
Over the edge: New therapeutic strategy takes advantage of stressed cancer cells EurekAlert!, 11 September 2006
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| Integrative Medicine > Cruciferous Vegetables | Etiology and Pathogenesis > ROS (Reactive Oxygen Species) | |
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Dunyaporn Trachootham, Yan Zhou, Hui Zhang, Yusuke Demizu, Zhao Chen, Helene
Pelicano, Paul J. Chiao, Geetha Achanta, Ralph B. Arlinghaus, Jinsong Liu and
Peng Huang
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate Cancer Cell, Volume 10, Issue 3, September 2006, Pages 241-252. Available online 11 September 2006.
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Mary Parlange Who gives stem cells their marching orders? EurekAlert!, 5 September 2006
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| Etiology and Pathogenesis > Stem Cells | |
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Nadav Ben-Haim,
Cindy Lu, Marcela Guzman-Ayala, Luca Pescatore, Daniel Mesnard, Mirko
Bischofberger, Felix Naef, Elizabeth J. Robertson and Daniel B.
Constam
The Nodal Precursor Acting via Activin Receptors Induces Mesoderm by Maintaining a Source of Its Convertases and BMP4 Developmental Cell, Volume 11, Issue 3, September 2006, Pages 313-323, doi:10.1016/j.devcel.2006.07.005, Available online 5 Sept 2006
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Cody Mooneyhan
Harvard scientists identify compounds that stimulate stem cell growth in the brain EurekAlert!, 1 September 2006 News
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| Etiology and Pathogenesis > Stem Cells | |
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Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation The FASEB Journal., Vol. 20, Num. 11, September 2006, Pages 1785-1792. Abstract
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Brain Tumors |
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Modafinil Ups
Cognitive Function in Brain Tumor Patients
Oncology News International, September 2006, Volume 15 Number 9
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| Quality of Life and Psychosocial Effects | |
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T. A. Kaleita, D. K. Wellisch, C. A. Graham, B. Steh,
P. Nghiemphu, J. M. Ford, A. Lai, S. Peak, T. F. Cloughesy
Pilot study of modafinil for treatment of neurobehavioral dysfunction and fatigue in adult patients with brain tumors Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings Part I. Vol 24, No. 18S (June 20 Supplement), 2006: 1503 
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Gliomas |
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Sandra Van
Combined therapies may boost immune response and long-term protection against brain tumors EurekAlert!, 1 September 2006
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| Etiology and Pathogenesis > Stem Cells | Immunotherapy | |
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Featured Article |
Induction of Potent Antitumor Immunity by Intratumoral Injection of Interleukin 23–Transduced Dendritic Cells Cancer Research 66, 8887-8896, September 1, 2006
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| Etiology and Pathogenesis > Stem Cells | Immunotherapy | |
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Interleukin-23–Expressing Bone Marrow–Derived Neural Stem-Like Cells Exhibit Antitumor Activity against Intracranial Glioma Cancer Research 66, 2630-2638, March 1, 2006
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BrainLife
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| Etiology and Pathogenesis > Stem Cells | |
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Peter Kabos, Moneeb Ehtesham, Andrea Kabosova, Keith L. Black and John S.
Yu
Generation of Neural Progenitor Cells from Whole Adult Bone Marrow Exp Neurol. 2002 Dec 20;178(2):288-93.
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| Etiology and Pathogenesis > Stem Cells | Immunotherapy | |
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Gentao Liu, Keith L
Black and John S Yu
Sensitization of malignant glioma to chemotherapy through dendritic cell vaccination Expert Review of Vaccines, Apr 2006, Vol. 5, No. 2, Pages 233-247
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| Etiology and Pathogenesis > Stem Cells | Immunotherapy | |
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Clinical Responsiveness of Glioblastoma Multiforme to Chemotherapy after Vaccination Clinical Cancer Research Vol. 10, 5316-5326, August 15, 2004
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Gliomatosis Cerebri |
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| Overall Management > Glial Tumors of Uncertain Origin | |
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Stefan Braeuninger, Regine Schneider-Stock,
Elmar Kirches, James M. Powers, David N. Korones
and Christian Mawrin
Evaluation of molecular genetic alterations associated with tumor progression in a case of gliomatosis cerebri Journal of Neuro-Oncology, DOI: 10.1007/s11060-006-9245-7, Published online: 6 September 2006
Abstract / BrainLife
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Medulloblastoma |
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John Ascenzi
Prenatal vitamins may reduce risk of brain tumors in children EurekAlert!, 20 September 2006
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| Epidemiology and Risk Factors | |
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Maternal Supplement, Micronutrient, and Cured Meat Intake during Pregnancy and Risk of Medulloblastoma during Childhood: A Children's Oncology Group Study Cancer Epidemiol Biomarkers Prev. 2006 Sep 1;15(9):1660-7
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Bonnie Kourvelas
Improved treatment raises medulloblastoma survival rate EurekAlert!, 7 September 2006
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Joe Santangelo
New strategy improves outcome for children with most common type of brain tumor EurekAlert!, 6 September 2006
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| Treatment > Cyclophosphamide / Radiotherapy | |
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Dr, Prof Amar Gajjar
MD, Murali Chintagumpala MD,
David Ashley MBBS, Stewart Kellie
MBBS, Prof Larry E Kun MD, Prof
Thomas E Merchant DO, Shaio Woo
MD, Greg Wheeler MBBS, Valerie Ahern
MBBS, Matthew J Krasin MD, Maryam Fouladi
MD, Alberto Broniscer MD, Prof
Robert Krance MD, Gregory A Hale
MD, Clinton F Stewart PharmD,
Robert Dauser MD, Prof
Robert A Sanford MD, Christine Fuller
MD, Ching Lau MD, Prof
James M Boyett PhD, Dana Wallace
MS and Richard J Gilbertson MD
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial Lancet Oncology Early Online Publication, 7 September 2006, DOI:10.1016/S1470-2045(06)70867-1
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