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NEWSLETTER
Volume 6, Number 2 - 8 January 2007

Volume 6
Archive


Contents


Diagnosis
Etiology & Pathogenesis
Overall Management
Treatment

Diagnosis


Celda B, Monleon D, Martinez-Bisbal MC, Esteve V, Martinez-Granados B, Pinero E, Ferrer R, Piquer J, Marti-Bonmati L, Cervera J. 
MRS as endogenous molecular imaging for brain and prostate tumors: FP6 project "eTUMOR".
Adv Exp Med Biol. 2006;587:285-302. Review.
PMID: 17163172 [PubMed - indexed for MEDLINE]
Lungu GF, Li ML, Xie X, Wang LV, Stoica G. 
In vivo imaging and characterization of hypoxia-induced neovascularization and tumor invasion.
Int J Oncol. 2007 Jan;30(1):45-54.
PMID: 17143511 [PubMed - indexed for MEDLINE]

Popescu MA, Toms SA. 
In vivo optical imaging using quantum dots for the management of brain tumors.
Expert Rev Mol Diagn. 2006 Nov;6(6):879-90. Review.
PMID: 17140375 [PubMed - indexed for MEDLINE]

Ram Z, Cohen ZR, Harnof S, Tal S, Faibel M, Nass D, Maier SE, Hadani M, Mardor Y. 
Magnetic resonance imaging-guided, high-intensity focused ultrasound for brain tumor therapy.
Neurosurgery. 2006 Nov;59(5):949-55; discussion 955-6.
PMID: 17143231 [PubMed - indexed for MEDLINE]

Schaller BJ, Modo M, Buchfelder M. 
Molecular imaging of brain tumors: a bridge between clinical and molecular medicine?
Mol Imaging Biol. 2007 Mar-Apr;9(2):60-71. Review.
PMID: 17203238 [PubMed - indexed for MEDLINE]

Schillaci O, Filippi L, Manni C, Santoni R. 
Single-photon emission computed tomography/computed tomography in brain tumors.
Semin Nucl Med. 2007 Jan;37(1):34-47. Review.
PMID: 17161038 [PubMed - indexed for MEDLINE]


Etiology & Pathogenesis


Bsibsi M, Bajramovic JJ, Van Duijvenvoorden E, Persoon C, Ravid R, Van Noort JM, Vogt MH. 
Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins.
Glia. 2007 Apr 1;55(5):473-82.
PMID: 17205552 [PubMed - indexed for MEDLINE]

Geng Y, Akhtar RS, Shacka JJ, Klocke BJ, Zhang J, Chen X, Roth KA. 
p53 transcription-dependent and -independent regulation of cerebellar neural precursor cell apoptosis.
J Neuropathol Exp Neurol. 2007 Jan;66(1):66-74.
PMID: 17204938 [PubMed - indexed for MEDLINE]

Kawaguchi T, Yamashita Y, Kanamori M, Endersby R, Bankiewicz KS, Baker SJ, Bergers G, Pieper RO. 
The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.
Cancer Res. 2006 Dec 1;66(23):11331-40.
PMID: 17145879 [PubMed - indexed for MEDLINE]

Learn CA, Grossi PM, Schmittling RJ, Xie W, Mitchell DA, Karikari I, Wei Z, Dressman H, Sampson JH. 
Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.
J Neuroimmunol. 2007 Jan;182(1-2):63-72. Epub 2006 Nov 29.
PMID: 17137636 [PubMed - indexed for MEDLINE]

Learn CA, Hartzell TL, Wikstrand CJ, Archer GE, Rich JN, Friedman AH, Friedman HS, Bigner DD, Sampson JH. 
Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme.
Clin Cancer Res. 2004 May 1;10(9):3216-24.
PMID: 15131063 [PubMed - indexed for MEDLINE]
Heimberger AB, Learn CA, Archer GE, McLendon RE, Chewning TA, Tuck FL, Pracyk JB, Friedman AH, Friedman HS, Bigner DD, Sampson JH. 
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).
Clin Cancer Res. 2002 Nov;8(11):3496-502.
PMID: 12429640 [PubMed - indexed for MEDLINE]
Yoo H, Baia GS, Smith JS, McDermott MW, Bollen AW, Vandenberg SR, Lamborn KR, Lal A. 
Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
Clin Cancer Res. 2007 Jan 1;13(1):68-75.
PMID: 17200340 [PubMed - indexed for MEDLINE]


Overall Management


Armstrong TS, Gilbert MR. 
Net clinical benefit: functional endpoints in brain tumor clinical trials.
Curr Oncol Rep. 2007 Jan;9(1):60-5. Review.
PMID: 17164049 [PubMed - indexed for MEDLINE]

Harpold HL, Alvord EC Jr, Swanson KR. 
The evolution of mathematical modeling of glioma proliferation and invasion.
J Neuropathol Exp Neurol. 2007 Jan;66(1):1-9. Review.
PMID: 17204931 [PubMed - indexed for MEDLINE]


Treatment


Ingrassia L, Camby I, Lefranc F, Mathieu V, Nshimyumukiza P, Darro F, Kiss R. 
Anti-galectin compounds as potential anti-cancer drugs.
Curr Med Chem. 2006;13(29):3513-27. Review.
PMID: 17168720 [PubMed - indexed for MEDLINE]

Kang SH, Cho HT, Devi S, Zhang Z, Escuin D, Liang Z, Mao H, Brat DJ, Olson JJ, Simons JW, Lavallee TM, Giannakakou P, Van Meir EG, Shim H. 
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
Cancer Res. 2006 Dec 15;66(24):11991-7.
PMID: 17178898 [PubMed - indexed for MEDLINE]

Styczynski J, Olszewska-Slonina D, Kolodziej B, Napieraj M, Wysocki M. 
Activity of bortezomib in glioblastoma.
Anticancer Res. 2006 Nov-Dec;26(6B):4499-503.
PMID: 17201170 [PubMed - indexed for MEDLINE]

Vogelbaum MA. 
Convection enhanced delivery for treating brain tumors and selected neurological disorders: symposium review.
J Neurooncol. 2007 May;83(1):97-109. Epub 2007 Jan 4.
PMID: 17203397 [PubMed - in process]

Yang Z, Xu J, Sang C. 
[Clinical studies on treatment of patients with malignant spinal tumors by percutaneous vertebroplasty under guidance of digital subtraction angiography]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2006 Oct;20(10):999-1003. Chinese.
PMID: 17140073 [PubMed - in process]

Zhao W, Payne V, Tommasi E, Diz DI, Hsu FC, Robbins ME. 
Administration of the peroxisomal proliferator-activated receptor gamma agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment.
Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):6-9.
PMID: 17189061 [PubMed - indexed for MEDLINE]

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