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NEWSLETTER
Volume 6, Number 25 - 18 June 2007

Volume 6
Archive


Contents


Early Detection
Diagnosis & Evaluation
Epidemiology & Risk Factors
Etiology & Pathogenesis
Integrative Medicine
Overall Management
Prognosis & Outcome
Psychosocial Aspects
Treatment
Children's Corner

Early Detection


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Crawford JR, Santi MR, Vezina G, Myseros JS, Keating RF, LaFond DA, Rood BR, MacDonald TJ, Packer RJ. 
CNS germ cell tumor (CNSGCT) of childhood: presentation and delayed diagnosis.
Neurology. 2007 May 15;68(20):1668-73.
PMID: 17502547 [PubMed - indexed for MEDLINE]

Park HY, Kim YH, Kim H, Koh WJ, Suh GY, Chung MP, Kwon OJ. 
Routine screening by brain magnetic resonance imaging decreased the brain metastasis rate following surgery for lung adenocarcinoma.
Lung Cancer. 2007 Jun 7; [Epub ahead of print]
PMID: 17560683 [PubMed - as supplied by publisher]


Diagnosis & Evaluation


Cha S, Lupo JM, Chen MH, Lamborn KR, McDermott MW, Berger MS, Nelson SJ, Dillon WP. 
Differentiation of Glioblastoma Multiforme and Single Brain Metastasis by Peak Height and Percentage of Signal Intensity Recovery Derived from Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging.
AJNR Am J Neuroradiol. 2007 Jun;28(6):1078-1084.
PMID: 17569962 [PubMed - as supplied by publisher]

Gultasli NZ, Ercan K, Orhun S, Albayrak S. 
MRI findings of intramedullary spinal cryptococcoma.
Diagn Interv Radiol. 2007 Jun;13(2):64-67.
PMID: 17562509 [PubMed - as supplied by publisher]

Jha AN, Rahmathulla G, Vaishya S, Walia BS, Gupta V. 
Intraoperative high field magnetic resonance imaging in neurosurgery: Our initial experience with the brain suite.
Neurol India. 2007 Apr-Jun;55(2):169-72.
PMID: 17558127 [PubMed - in process]

Kane RA, Kruskal JB. 
Intraoperative ultrasonography of the brain and spine.
Ultrasound Q. 2007 Mar;23(1):23-39.
PMID: 17558210 [PubMed - in process]

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Lin D, Najbauer J, Salvaterra PM, Mamelak AN, Barish ME, Garcia E, Metz MZ, Kendall SE, Bowers M, Kateb B, Kim SU, Johnson M, Aboody KS. 
Novel method for visualizing and modeling the spatial distribution of neural stem cells within intracranial glioma.
Neuroimage. 2007 May 13; [Epub ahead of print]
PMID: 17560798 [PubMed - as supplied by publisher]

Nemeth AJ, Henson JW, Mullins ME, Gonzalez RG, Schaefer PW. 
Improved Detection of Skull Metastasis with Diffusion-Weighted MR Imaging.
AJNR Am J Neuroradiol. 2007 Jun;28(6):1088-1092.
PMID: 17569964 [PubMed - as supplied by publisher]


Epidemiology & Risk Factors


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Moore SW, Sasco AJ, Dechelotte P, Satge D. 
In vitro fertilization and brain tumors.
J Neurosurg. 2007 May;106(5 Suppl):418; author reply 418-9. No abstract available.
PMID: 17566216 [PubMed - in process]


Etiology & Pathogenesis


El Hallani S, Marie Y, Idbaih A, Rodero M, Boisselier B, Laigle-Donadey F, Ducray F, Delattre JY, Sanson M. 
No association of MDM2 SNP309 with risk of glioblastoma and prognosis.
J Neurooncol. 2007 Jun 14; [Epub ahead of print]
PMID: 17568997 [PubMed - as supplied by publisher]

Hattingen E, Raab P, Franz K, Zanella FE, Lanfermann H, Pilatus U. 
Myo-Inositol: a marker of reactive astrogliosis in glial tumors?
NMR Biomed. 2007 Jun 11; [Epub ahead of print]
PMID: 17562554 [PubMed - as supplied by publisher]

Kim SH, Cheong JW, Park KH, Kim TS, Yang WI. 
Comparison of ataxia-telangiectasia mutated protein expression in diffuse large B-cell lymphomas of primary central nervous system and non-central nervous system origin.
Arch Pathol Lab Med. 2007 Mar;131(3):457-67.
PMID: 17516749 [PubMed - indexed for MEDLINE]

Lu X, Kang Y.
Organotropism of Breast Cancer Metastasis.
J Mammary Gland Biol Neoplasia. 2007 Jun 14; [Epub ahead of print]
PMID: 17566854 [PubMed - as supplied by publisher]

Ng SS, Cheung YT, An XM, Chen YC, Li M, Hoi-Yee Li G, Cheung W, Sze J, Lai L, Peng Y, Xia HH, Wong BC, Leung SY, Xie D, He ML, Kung HF, Lin MC. 
Cell Cycle-Related Kinase: A Novel Candidate Oncogene in Human Glioblastoma.
J Natl Cancer Inst. 2007 Jun 12; [Epub ahead of print]
PMID: 17565152 [PubMed - as supplied by publisher]

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Palmieri D, Chambers AF, Felding-Habermann B, Huang S, Steeg PS. 
The biology of metastasis to a sanctuary site.
Clin Cancer Res. 2007 Mar 15;13(6):1656-62. Review.
PMID: 17363518 [PubMed - indexed for MEDLINE]

Ren B, Yu YP, Tseng GC, Wu C, Chen K, Rao UN, Nelson J, Michalopoulos GK, Luo JH. 
Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.
J Natl Cancer Inst. 2007 Jun 6;99(11):868-80.
PMID: 17551147 [PubMed - in process]

Schmitz M, Temme A, Senner V, Ebner R, Schwind S, Stevanovic S, Wehner R, Schackert G, Schackert HK, Fussel M, Bachmann M, Rieber EP, Weigle B. 
Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy.
Br J Cancer. 2007 Jun 18;96(12):1928. Epub 2007 Jun 12. No abstract available.
PMID: 17565344 [PubMed - in process]

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Salgado KB, Toscani NV, Silva LL, Hilbig A, Barbosa-Coutinho LM. 
Immunoexpression of endoglin in brain metastasis secondary to malignant melanoma: evaluation of angiogenesis and comparison with brain metastasis secondary to breast and lung carcinomas.
Clin Exp Metastasis. 2007 Jun 13; [Epub ahead of print]
PMID: 17564791 [PubMed - as supplied by publisher]

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Seaman S, Stevens J, Yang MY, Logsdon D, Graff-Cherry C, St Croix B. 
Genes that Distinguish Physiological and Pathological Angiogenesis.
Cancer Cell. 2007 Jun;11(6):539-54.
PMID: 17560335 [PubMed - in process]

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Uesaka T, Shono T, Suzuki SO, Nakamizo A, Niiro H, Mizoguchi M, Iwaki T, Sasaki T. 
Expression of VEGF and its receptor genes in intracranial schwannomas.
J Neurooncol. 2007 Jul;83(3):259-266. Epub 2007 Feb 14.
PMID: 17570036 [PubMed - as supplied by publisher]

Wang DL, Wang YF, Shi GS, Huang H. 
[Correlation of hTERT Expression to Maspin and bFGF Expression and Their Significance in Glioma.]
Ai Zheng. 2007 Jun;26(6):601-6. Chinese.
PMID: 17562265 [PubMed - in process]


Integrative Medicine


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Karmakar S, Banik NL, Ray SK. 
Curcumin Suppressed Anti-apoptotic Signals and Activated Cysteine Proteases for Apoptosis in Human Malignant Glioblastoma U87MG Cells.
Neurochem Res. 2007 Jun 12; [Epub ahead of print]
PMID: 17562168 [PubMed - as supplied by publisher]

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Natali F, Siculella L, Salvati S, Gnoni GV. 
Oleic acid is a potent inhibitor of fatty acid and cholesterol syntheses in C6 glioma cells.
J Lipid Res. 2007 Jun 13; [Epub ahead of print]
PMID: 17568062 [PubMed - as supplied by publisher]


Overall Management


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Aragon-Ching JB, Zujewski JA. 
CNS metastasis: an old problem in a new guise.
Clin Cancer Res. 2007 Mar 15;13(6):1644-7. Review.
PMID: 17363516 [PubMed - indexed for MEDLINE]

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Carrato-Monino C, Ariza A. 
[Oligodendrogliomas: their morphological characteristics and molecular alterations]
Rev Neurol. 2007 Mar 16-31;44(6):353-9. Review. Spanish.
PMID: 17385172 [PubMed - indexed for MEDLINE]

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Deeken JF, Loscher W. 
The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.
Clin Cancer Res. 2007 Mar 15;13(6):1663-74. Review.
PMID: 17363519 [PubMed - indexed for MEDLINE]

Piccirilli M, Sassun TE, Brogna C, Giangaspero F, Salvati M.
Late brain metastases from breast cancer: clinical remarks on 11 patients and review of the literature.
Tumori. 2007 Mar-Apr;93(2):150-4.
PMID: 17557561 [PubMed - in process]

Poindexter G, Metry DW, Barkovich AJ, Frieden IJ. 
PHACE Syndrome with Intracerebral Hemangiomas, Heterotopia, and Endocrine Dysfunction.
Pediatr Neurol. 2007 Jun;36(6):402-6.
PMID: 17560503 [PubMed - in process]

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Puget S, Crimmins DW, Garnett MR, Grill J, Oliveira R, Boddaert N, Wray A, Lelouch-Tubiana A, Roujeau T, Di Rocco F, Zerah M, Sainte-Rose C. 
Thalamic tumors in children: a reappraisal.
J Neurosurg. 2007 May;106(5 Suppl):354-62.
PMID: 17566201 [PubMed - in process]

Song JK, Niimi Y, Kupersmith MJ, Berenstein A. 
Postnatal growth and development of a cerebral arteriovenous malformation on serial magnetic resonance imaging in a child with hemangiomatosis. Case report.
J Neurosurg. 2007 May;106(5 Suppl):384-7.
PMID: 17566206 [PubMed - in process]

Tamaki K, Shimizu I, Urata M, Kohno N, Fukuno H, Ito S, Sano N. 
A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings.
World J Gastroenterol. 2007 May 21;13(19):2758-60.
PMID: 17569150 [PubMed - in process]

Utsuki S, Oka H, Sagiuchi T, Fujii K. 
Late intrathoracic relapse of pineal germinoma connected to intraspinal canal.
Neurol India. 2007 Apr-Jun;55(2):151-3.
PMID: 17558121 [PubMed - in process]


Prognosis & Outcome


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Kramar F, Zemanova Z, Michalova K, Babicka L, Ransdorfova S, Hrabal P, Kozler P. 
Cytogenetic analyses in 81 patients with brain gliomas: correlation with clinical outcome and morphological data.
J Neurooncol. 2007 Jun 14; [Epub ahead of print]
PMID: 17569001 [PubMed - as supplied by publisher]

Smith JS, Lal A, Harmon-Smith M, Bollen AW, McDermott MW. 
Association between absence of epidermal growth factor receptor immunoreactivity and poor prognosis in patients with atypical meningioma.
J Neurosurg. 2007 Jun;106(6):1034-40.
PMID: 17564176 [PubMed - in process]

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Skowronska-Gardas A, Chojnacka M, Morawska-Kaczynska M, Perek D, Perek-Polnik M. 
Patterns of failure in children with medulloblastoma treated with 3D conformal radiotherapy.
Radiother Oncol. 2007 Jun 7; [Epub ahead of print]
PMID: 17560676 [PubMed - as supplied by publisher]


Psychosocial Aspects


Conklin HM, Khan RB, Reddick WE, Helton S, Brown R, Howard SC, Bonner M, Christensen R, Wu S, Xiong X, Mulhern RK. 
Acute Neurocognitive Response to Methylphenidate Among Survivors of Childhood Cancer: A Randomized, Double-Blind, Cross-Over Trial.
J Pediatr Psychol. 2007 Jun 14; [Epub ahead of print]
PMID: 17569711 [PubMed - as supplied by publisher]

Gerhardt CA, Yopp JM, Leininger L, Valerius KS, Correll J, Vannatta K, Noll RB. 
Brief Report: Post-traumatic Stress During Emerging Adulthood in Survivors of Pediatric Cancer.
J Pediatr Psychol. 2007 Jun 12; [Epub ahead of print]
PMID: 17566005 [PubMed - as supplied by publisher]

Iizuka O, Suzuki K, Mori E. 
Severe amnesic syndrome and collecting behavior after surgery for craniopharyngioma.
Cogn Behav Neurol. 2007 Jun;20(2):126-30.
PMID: 17558257 [PubMed - in process]


Treatment


Beck TJ, Kreth FW, Beyer W, Mehrkens JH, Obermeier A, Stepp H, Stummer W, Baumgartner R. 
Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX.
Lasers Surg Med. 2007 Jun 12;39(5):386-393 [Epub ahead of print]
PMID: 17565715 [PubMed - as supplied by publisher]

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Belen D, Er U, Yigitkanli K, Bolay H. 
Delayed neurotoxic complication of intracavitary bleomycin therapy for craniopharyngioma in a child who had previously undergone radiosurgery. Case report.
J Neurosurg. 2007 May;106(5 Suppl):391-3.
PMID: 17566208 [PubMed - in process]

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Burn S, Gunny R, Phipps K, Gaze M, Hayward R. 
Incidence of cavernoma development in children after radiotherapy for brain tumors.
J Neurosurg. 2007 May;106(5 Suppl):379-83.
PMID: 17566205 [PubMed - in process]

Carapancea M, Cosaceanu D, Budiu R, Kwiecinska A, Tataranu L, Ciubotaru V, Alexandru O, Banita M, Pisoschi C, Backlund ML, Lewensohn R, Dricu A. 
Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells.
J Neurooncol. 2007 Jun 14; [Epub ahead of print]
PMID: 17568996 [PubMed - as supplied by publisher]

Carrabba G, Fava E, Giussani C, Acerbi F, Portaluri F, Songa V, Stocchetti N, Branca V, Gaini SM, Bello L. 
Cortical and subcortical motor mapping in rolandic and perirolandic glioma surgery: impact on postoperative morbidity and extent of resection.
J Neurosurg Sci. 2007 Jun;51(2):45-51.
PMID: 17571034 [PubMed - as supplied by publisher]

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Chen AM, Jahan TM, Jablons DM, Garcia J, Larson DA. 
Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: clinical implications for the subsequent management of the brain.
Cancer. 2007 Apr 15;109(8):1668-75.
PMID: 17342770 [PubMed - indexed for MEDLINE]

Chu SH, Zhang H, Ma YB, Feng DF, Zhu ZA, Yuan XH, Li ZQ. 
c-Met Antisense Oligodeoxynucleotides as a Novel Therapeutic Agent for Glioma: In Vitro and In Vivo Studies of Uptake, Effects, and Toxicity.
J Surg Res. 2007 Jun 8; [Epub ahead of print]
PMID: 17561117 [PubMed - as supplied by publisher]

Combs SE, Schulz-Ertner D, Roth W, Herold-Mende C, Debus J, Weber KJ. 
In vitro responsiveness of glioma cell lines to multimodality treatment with radiotherapy, temozolomide, and epidermal growth factor receptor inhibition with cetuximab.
Int J Radiat Oncol Biol Phys. 2007 Jul 1;68(3):873-82.
PMID: 17544000 [PubMed - in process]
Douglas JG, Arndt CA, Hawkins DS. 
Delayed radiotherapy following dose intensive chemotherapy for parameningeal rhabdomyosarcoma (PM-RMS) of childhood.
Eur J Cancer. 2007 Apr;43(6):1045-50.
PMID: 17368885 [PubMed - indexed for MEDLINE]

Dwarakanath S, Suri A, Sharma BS, Mahapatra AK. 
Neuronavigation in a developing country: A pilot study of efficacy and limitations in intracranial surgery.
Neurol India. 2007 Apr-Jun;55(2):111-6.
PMID: 17558113 [PubMed - in process]

Ford JM, Seiferheld W, Alger JR, Wu G, Endicott TJ, Mehta M, Curran W, Phan SC. 
Results of the Phase I Dose-Escalating Study of Motexafin Gadolinium with Standard Radiotherapy in Patients with Glioblastoma Multiforme.
Int J Radiat Oncol Biol Phys. 2007 Jun 7; [Epub ahead of print]
PMID: 17560737 [PubMed - as supplied by publisher]

Kajimoto Y, Kuroiwa T, Miyatake S, Ichioka T, Miyashita M, Tanaka H, Tsuji M. 
Use of 5-aminolevulinic acid in fluorescence-guided resection of meningioma with high risk of recurrence. Case report.
J Neurosurg. 2007 Jun;106(6):1070-4.
PMID: 17564181 [PubMed - in process]

Kanner AA, Bokstein F, Blumenthal DT, Ram Z. 
Surgical therapies in brain metastasis.
Semin Oncol. 2007 Jun;34(3):197-205.
PMID: 17560981 [PubMed - in process]

Kanto S, Tokuyama S, Numahata K, Nakagawa H, Saito S, Arai Y. 
[Occult lumbar vertebral body metastasis of non-seminomatous germ cell tumor eradicated by radiation and salvage surgery 9 years after initial onset]
Nippon Hinyokika Gakkai Zasshi. 2007 May;98(4):634-7. Japanese.
PMID: 17564107 [PubMed - in process]

Mariani CL, Rajon D, Bova FJ, Streit WJ. 
Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas.
J Neurooncol. 2007 Jun 14; [Epub ahead of print]
PMID: 17568998 [PubMed - as supplied by publisher]

Maton B, Resnick T, Jayakar P, Morrison G, Duchowny M.
Epilepsy Surgery in Children with Gliomatosis Cerebri.
Epilepsia. 2007 Jun 12; [Epub ahead of print]
PMID: 17565595 [PubMed - as supplied by publisher]

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Mattozo CA, De Salles AA, Klement IA, Gorgulho A, McArthur D, Ford JM, Agazaryan N, Kelly DF, Selch MT. 
Stereotactic radiation treatment for recurrent nonbenign meningiomas.
J Neurosurg. 2007 May;106(5):846-54.
PMID: 17542529 [PubMed - in process]

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Muldoon LL, Soussain C, Jahnke K, Johanson C, Siegal T, Smith QR, Hall WA, Hynynen K, Senter PD, Peereboom DM, Neuwelt EA. 
Chemotherapy delivery issues in central nervous system malignancy: a reality check.
J Clin Oncol. 2007 Jun 1;25(16):2295-305. Review.
PMID: 17538176 [PubMed - indexed for MEDLINE]

Pernot M, Aubry JF, Tanter M, Boch AL, Marquet F, Kujas M, Seilhean D, Fink M. 
In vivo transcranial brain surgery with an ultrasonic time reversal mirror.
J Neurosurg. 2007 Jun;106(6):1061-6.
PMID: 17564179 [PubMed - in process]

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Pouliquen DL. 
Hepatic mitochondrial function and brain tumours.
Curr Opin Clin Nutr Metab Care. 2007 Jul;10(4):475-9.
PMID: 17563466 [PubMed - in process]

Stuhr LE, Raa A, Oyan AM, Kalland KH, Sakariassen PO, Petersen K, Bjerkvig R, Reed RK. 
Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats.
J Neurooncol. 2007 Jun 8; [Epub ahead of print]
PMID: 17557137 [PubMed - as supplied by publisher]

Sunyach MP, Jouvet A, Perol D, Jouanneau E, Guyotat J, Gignoux L, Carrie C, Frappaz D. 
Role of exclusive chemotherapy as first line treatment in oligodendroglioma.
J Neurooncol. 2007 Jun 14; [Epub ahead of print]
PMID: 17568995 [PubMed - as supplied by publisher]


Children's Corner



Elisabetta Mancini
Il sogno di Giņ (Jo's Dream
English translation by
Jane Wilson & Jaqueline Hargrave
BrainLife, 18 June 2007

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