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NEWSLETTER
Volume 6, Number 26 - 25 June 2007

Volume 6
Archive


Contents


Diagnosis & Evaluation
Epidemiology & Risk Factors
Etiology & Pathogenesis
Integrative Medicine
Overall Management
Prognosis & Outcome
Treatment
Children's Corner

Diagnosis & Evaluation


Cha S, Lupo JM, Chen MH, Lamborn KR, McDermott MW, Berger MS, Nelson SJ, Dillon WP.
Differentiation of Glioblastoma Multiforme and Single Brain Metastasis by Peak Height and Percentage of Signal Intensity Recovery Derived from Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging.
AJNR Am J Neuroradiol. 2007 Jun;28(6):1078-84.
PMID: 17569962 [PubMed - in process]

Chen LG, Zhou MJ, Tan AW, Wang SX, He SZ, Ding ZH.
[Positron emission tomography with L-[S-methyl-(11)C]-methioine and its biodistribution.]
Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jun;27(6):834-5. Chinese.
PMID: 17584651 [PubMed - in process]
Jarzembowski J, Lloyd R, McKeever P.
Type IV collagen immunostaining is a simple, reliable diagnostic tool for distinguishing between adenomatous and normal pituitary glands.
Arch Pathol Lab Med. 2007 Jun;131(6):931-5.
PMID: 17550321 [PubMed - indexed for MEDLINE]

Kasliwal MK, Chandra PS, Sharma BS.
Images in neuro oncology: primary extraaxial cerebellopontine angle ependymoma.
J Neurooncol. 2007 May;83(1):31-2. Epub 2007 Mar 30.
PMID: 17396227 [PubMed - indexed for MEDLINE]
Kwee SA, Ko JP, Jiang CS, Watters MR, Coel MN.
Solitary Brain Lesions Enhancing at MR Imaging: Evaluation with Fluorine 18-Fluorocholine PET.
Radiology. 2007 Jun 20; [Epub ahead of print]
PMID: 17581887 [PubMed - as supplied by publisher]

Li XA, Qi XS, Pitterle M, Kalakota K, Mueller K, Erickson BA, Wang D, Schultz CJ, Firat SY, Wilson JF.
Interfractional variations in patient setup and anatomic change assessed by daily computed tomography.
Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):581-91. Epub 2007 Feb 27.
PMID: 17331669 [PubMed - indexed for MEDLINE]

Muthukrishnan A, Bajoghli M, Mountz JM.
Delayed Development of Radiation Vasculopathy of the Brain Stem Confirmed by F-18 FDG PET in a Case of Anaplastic Astrocytoma.
Clin Nucl Med. 2007 Jul;32(7):527-31.
PMID: 17581336 [PubMed - in process]

Sousa R, Sa G, Reimao S, Lopes L, Ruivo J, Albuquerque L, Campos J.
[Adult cerebellar medulloblastoma: imaging findings in eight cases]
Acta Med Port. 2006 Nov-Dec;19(6):466-70. Epub 2007 May 14. Portuguese.
PMID: 17583605 [PubMed - in process]

Vijayakumar C, Damayanti G, Pant R, Sreedhar CM.
Segmentation and grading of brain tumors on apparent diffusion coefficient images using self-organizing maps.
Comput Med Imaging Graph. 2007 Jun 13; [Epub ahead of print]
PMID: 17572068 [PubMed - as supplied by publisher]

Wyss MT, Hofer S, Hefti M, Bartschi E, Uhlmann C, Treyer V, Roelcke U.
Spatial Heterogeneity of Low-Grade Gliomas at the Capillary Level: A PET Study on Tumor Blood Flow and Amino Acid Uptake.
J Nucl Med. 2007 Jun 15; [Epub ahead of print]
PMID: 17574979 [PubMed - as supplied by publisher]


Epidemiology & Risk Factors


*

Claus EB, Black PM, Bondy ML, Calvocoressi L, Schildkraut JM, Wiemels JL, Wrensch M.
Exogenous hormone use and meningioma risk: what do we tell our patients?
Cancer. 2007 Jun 19; [Epub ahead of print]
PMID: 17580362 [PubMed - as supplied by publisher]

Pelletier EM, Shim B, Goodman S, Amonkar MM.
Epidemiology and economic burden of brain metastases among patients with primary breast cancer: results from a US claims data analysis.
Breast Cancer Res Treat. 2007 Jun 19; [Epub ahead of print]
PMID: 17577662 [PubMed - as supplied by publisher]


Etiology & Pathogenesis


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Beckner ME, Jane EP, Jankowitz B, Agostino NR, Walter KA, Hamilton RL, Pollack IF. 
Tumor cells from ultrasonic aspirations of glioblastomas migrate and form spheres with radial outgrowth.
Cancer Lett. 2007 May 30; [Epub ahead of print]
PMID: 17543444 [PubMed - as supplied by publisher]

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Birnbaum T, Roider J, Schankin CJ, Padovan CS, Schichor C, Goldbrunner R, Straube A.
Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines.
J Neurooncol. 2007 Jul;83(3):241-247. Epub 2007 Feb 14.
PMID: 17570034 [PubMed - as supplied by publisher]
French PJ, Peeters J, Horsman S, Duijm E, Siccama I, van den Bent MJ, Luider TM, Kros JM, van der Spek P, Sillevis Smitt PA.
Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays.
Cancer Res. 2007 Jun 15;67(12):5635-42.
PMID: 17575129 [PubMed - in process]

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Gilbertson RJ, Gutmann DH.
Tumorigenesis in the brain: location, location, location.
Cancer Res. 2007 Jun 15;67(12):5579-82.
PMID: 17575119 [PubMed - in process]

Gomel R, Xiang C, Finniss S, Lee HK, Lu W, Okhrimenko H, Brodie C.
The Localization of Protein Kinase C{delta} in Different Subcellular Sites Affects Its Proapoptotic and Antiapoptotic Functions and the Activation of Distinct Downstream Signaling Pathways.
Mol Cancer Res. 2007 Jun;5(6):627-39.
PMID: 17579121 [PubMed - in process]

Huang J, Hu J, Bian X, Chen K, Gong W, Dunlop NM, Howard OM, Wang JM.
Transactivation of the epidermal growth factor receptor by formylpeptide receptor exacerbates the malignant behavior of human glioblastoma cells.
Cancer Res. 2007 Jun 15;67(12):5906-13.
PMID: 17575160 [PubMed - in process]

Korner M, Stockli M, Waser B, Reubi JC.
GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting.
J Nucl Med. 2007 May;48(5):736-43.
PMID: 17475961 [PubMed - indexed for MEDLINE]

Lindsey JC, Lusher ME, Anderton JA, Gilbertson RJ, Ellison DW, Clifford SC.
Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma.
Br J Cancer. 2007 Jun 19; [Epub ahead of print]
PMID: 17579622 [PubMed - as supplied by publisher]

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Mineo JF, Bordron A, Baroncini M, Maurage CA, Ramirez C, Siminski RM, Berthou C, Dam Hieu P.
Low HER2-expressing glioblastomas are more often secondary to anaplastic transformation of low-grade glioma.
J Neurooncol. 2007 Jun 15; [Epub ahead of print]
PMID: 17571214 [PubMed - as supplied by publisher]
Olson MV, Johnson DG, Jiang H, Xu J, Alonso MM, Aldape KD, Fuller GN, Bekele BN, Yung WK, Gomez-Manzano C, Fueyo J.
Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.
Cancer Res. 2007 May 1;67(9):4005-9.
PMID: 17483310 [PubMed - indexed for MEDLINE]

Palmieri D, Bronder JL, Herring JM, Yoneda T, Weil RJ, Stark AM, Kurek R, Vega-Valle E, Feigenbaum L, Halverson D, Vortmeyer AO, Steinberg SM, Aldape K, Steeg PS.
Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.
Cancer Res. 2007 May 1;67(9):4190-8.
PMID: 17483330 [PubMed - indexed for MEDLINE]

Pang Y, Zheng B, Fan LW, Rhodes PG, Cai Z.
IGF-1 protects oligodendrocyte progenitors against TNFalpha-induced damage by activation of PI3K/Akt and interruption of the mitochondrial apoptotic pathway.
Glia. 2007 Jun 18; [Epub ahead of print]
PMID: 17577243 [PubMed - as supplied by publisher]

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Pfenninger CV, Roschupkina T, Hertwig F, Kottwitz D, Englund E, Bengzon J, Jacobsen SE, Nuber UA.
CD133 Is Not Present on Neurogenic Astrocytes in the Adult Subventricular Zone, but on Embryonic Neural Stem Cells, Ependymal Cells, and Glioblastoma Cells.
Cancer Res. 2007 Jun 15;67(12):5727-36.
PMID: 17575139 [PubMed - in process]

Tsuno T, Natsume A, Katsumata S, Mizuno M, Fujita M, Osawa H, Nakahara N, Wakabayashi T, Satoh Y, Inagaki M, Yoshida J.
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.
J Neurooncol. 2007 Jul;83(3):249-58. Epub 2007 Feb 14.
PMID: 17570035 [PubMed - in process]

Integrative Medicine


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Chen KC, Hsieh CL, Peng CC, Hsieh-Li HM, Chiang HS, Huang KD, Peng RY.
Brain Derived Metastatic Prostate Cancer DU-145 Cells Are Effectively Inhibited In Vitro by Guava (Psidium gujava L.) Leaf Extracts.
Nutr Cancer. 2007;58(1):93-106.
PMID: 17571972 [PubMed - in process]


Overall Management


**

Beaumont TL, Kupsky WJ, Barger GR, Sloan AE.
Gliosarcoma with multiple extracranial metastases: case report and review of the literature.
J Neurooncol. 2007 May;83(1):39-46. Epub 2006 Dec 14. Review.
PMID: 17171442 [PubMed - indexed for MEDLINE]

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Bessell EM, Hoang-Xuan K, Ferreri AJ, Reni M.
Primary central nervous system lymphoma: biological aspects and controversies in management.
Eur J Cancer. 2007 May;43(7):1141-52. Epub 2007 Apr 12. Review.
PMID: 17433666 [PubMed - indexed for MEDLINE]

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Bexell D, Gunnarsson S, Nordquist J, Bengzon J.
Characterization of the subventricular zone neurogenic response to rat malignant brain tumors.
Neuroscience. 2007 Jun 19; [Epub ahead of print]
PMID: 17583435 [PubMed - as supplied by publisher]

Bradley S, Sherwood PR, Donovan HS, Hamilton R, Rosenzweig M, Hricik A, Newberry A, Bender C.
I could lose everything: understanding the cost of a brain tumor.
J Neurooncol. 2007 Jun 21; [Epub ahead of print]
PMID: 17581698 [PubMed - as supplied by publisher]
Dagnew E, Langford LA, Lang FF, DeMonte F.
Papillary tumors of the pineal region: case report.
Neurosurgery. 2007 May;60(5):E953-5; discussion E953-5.
PMID: 17460510 [PubMed - indexed for MEDLINE]

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Drappatz J, Batchelor TT.
Leptomeningeal Neoplasms.
Curr Treat Options Neurol. 2007 Jul;9(4):283-293.
PMID: 17580008 [PubMed - as supplied by publisher]

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Ewend MG, Brem S, Gilbert M, Goodkin R, Penar PL, Varia M, Cush S, Carey LA.
Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.
Clin Cancer Res. 2007 Jun 15;13(12):3637-41.
PMID: 17575228 [PubMed - in process

*

Fraioli MF, Contratti F, Fraioli C.
Craniopharyngioma.
J Neurosurg. 2007 Jun;106(6 Suppl):517-9; author reply 519. No abstract available.
PMID: 17571327 [PubMed - in process]

Holmoy T, Nakstad PH, Fredo HL, Kumar T.
Intravascular large B-cell lymphoma presenting as cerebellar and cerebral infarction.
Arch Neurol. 2007 May;64(5):754-5. No abstract available.
PMID: 17502477 [PubMed - indexed for MEDLINE]

Jinhu Y, Jianping D, Jun M, Hui S, Yepeng F.
Metastasis of a histologically benign choroid plexus papilloma: case report and review of the literature.
J Neurooncol. 2007 May;83(1):47-52. Epub 2007 Mar 27. Review.
PMID: 17387433 [PubMed - indexed for MEDLINE]
Kaal EC, Vecht CJ.
CNS complications of breast cancer : current and emerging treatment options.
CNS Drugs. 2007;21(7):559-79.
PMID: 17579499 [PubMed - in process]

Komotar RJ, O'Toole JE, Mocco J, Khandji AG, Keller CE, Connolly ES Jr, Bilsky MH, McCormick PC.
Gangliocytoma of the spinal cord.
Neurosurgery. 2007 May;60(5):895-900; discussion 895-900. No abstract available.
PMID: 17460525 [PubMed - indexed for MEDLINE]

Pal E, Aschermann Z, Gomori E, Kovacs GG, Simon G, Marodi L, Komoly S, Illes Z.
[Progressive multifocal leukoencephalopathy]
Ideggyogy Sz. 2007 May 30;60(5-6):263-8. Hungarian.
PMID: 17578275 [PubMed - in process]

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Vieira Santos A, Vilela P, Mateus L, Saraiva PF, Goulao A.
[Central nervous system abnormalities namely secondary brain tumors]
Acta Med Port. 2006 Nov-Dec;19(6):451-4. Epub 2007 May 14. Portuguese.
PMID: 17583602 [PubMed - in process]


Prognosis & Outcome


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Carson KA, Grossman SA, Fisher JD, Shaw EG.
Prognostic factors for survival in adult patients with recurrent glioma enrolled onto the new approaches to brain tumor therapy CNS consortium phase I and II clinical trials.
J Clin Oncol. 2007 Jun 20;25(18):2601-6.
PMID: 17577040 [PubMed - in process]

Kharkar S, Shuck J, Conway J, Rigamonti D.
The natural history of conservatively managed symptomatic intramedullary spinal cord cavernomas.
Neurosurgery. 2007 May;60(5):865-72; discussion 865-72.
PMID: 17460522 [PubMed - indexed for MEDLINE]

Levin VA, Jochec JL, Shantz LM, Aldape KD.
Relationship between ornithine decarboxylase levels in anaplastic gliomas and progression-free survival in patients treated with DFMO-PCV chemotherapy.
Int J Cancer. 2007 Jun 20; [Epub ahead of print]
PMID: 17582600 [PubMed - as supplied by publisher]

*

Osuka S, Tsuboi K, Takano S, Ishikawa E, Matsushita A, Tokuuye K, Akine Y, Matsumura A.
Long-term outcome of patients with intracranial germinoma.
J Neurooncol. 2007 May;83(1):71-9. Epub 2007 Jan 24.
PMID: 17245622 [PubMed - indexed for MEDLINE]

*

Trost D, Ehrler M, Fimmers R, Felsberg J, Sabel MC, Kirsch L, Schramm J, Wiestler OD, Reifenberger G, Weber RG.
Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors.
Int J Cancer. 2007 Jun 1;120(11):2368-76.
PMID: 17285580 [PubMed - indexed for MEDLINE]

*

Wahab SH, Simpson JR, Michalski JM, Mansur DB.
Long term outcome with post-operative radiation therapy for spinal canal ependymoma.
J Neurooncol. 2007 May;83(1):85-9. Epub 2007 Jan 6.
PMID: 17206474 [PubMed - indexed for MEDLINE]


Treatment


Ahmed N, Ratnayake M, Savoldo B, Perlaky L, Dotti G, Wels WS, Bhattacharjee MB, Gilbertson RJ, Shine HD, Weiss HL, Rooney CM, Heslop HE, Gottschalk S. 
Regression of Experimental Medulloblastoma following Transfer of HER2-Specific T Cells.
Cancer Res. 2007 Jun 15;67(12):5957-5964.
PMID: 17575166 [PubMed - as supplied by publisher]
 

*

Barani IJ, Benedict SH, Lin PS.
Neural stem cells: implications for the conventional radiotherapy of central nervous system malignancies.
Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):324-33. Epub 2007 Mar 29. Review.
PMID: 17398036 [PubMed - indexed for MEDLINE]

Cohen-Jonathan Moyal E, Laprie A, Delannes M, Poublanc M, Catalaa I, Dalenc F, Berchery D, Sabatier J, Bousquet P, De Porre P, Alaux B, Toulas C.
Phase I Trial of Tipifarnib (R115777) Concurrent with Radiotherapy in Patients with Glioblastoma Multiforme.
Int J Radiat Oncol Biol Phys. 2007 Jun 12; [Epub ahead of print]
PMID: 17570606 [PubMed - as supplied by publisher]

Daga A, Orengo AM, Gangemi RM, Marubbi D, Perera M, Comes A, Ferrini S, Corte G.
Glioma immunotherapy by IL-21 gene-modified cells or by recombinant IL-21 involves antibody responses.
Int J Cancer. 2007 Jun 20; [Epub ahead of print]
PMID: 17582604 [PubMed - as supplied by publisher]

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Ekenel M, Deangelis LM.
Treatment of primary central nervous system lymphoma.
Curr Treat Options Neurol. 2007 Jul;9(4):271-82.
PMID: 17580007 [PubMed - in process]

George J, Gondi CS, Dinh DH, Gujrati M, Rao JS.
Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis.
Clin Cancer Res. 2007 Jun 15;13(12):3507-17.
PMID: 17575213 [PubMed - in process]

**

Irwin C, Hunn M, Purdie G, Hamilton D.
Delay in radiotherapy shortens survival in patients with high grade glioma.
J Neurooncol. 2007 Jun 20; [Epub ahead of print]
PMID: 17579810 [PubMed - as supplied by publisher]
Jeremic B, Pitz S.
Primary optic nerve sheath meningioma: stereotactic fractionated radiation therapy as an emerging treatment of choice.
Cancer. 2007 Jun 20; [Epub ahead of print]
PMID: 17582618 [PubMed - as supplied by publisher]

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Silvani A, Lamperti E, Gaviani P, Eoli M, Fiumani A, Salmaggi A, Falcone C, Filippini G, Botturi A, Boiardi A.
Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patients.
J Neurooncol. 2007 Jun 19; [Epub ahead of print]
PMID: 17576523 [PubMed - as supplied by publisher]
Slampa P, Burkon P, Sterba J, Seneklova Z, Dembicka D, Burianova L.
The technique of craniospinal irradiation in the management of intracranial ependymomas.
J BUON. 2002 Apr-Jun;7(2):131-6.
PMID: 17577276 [PubMed - in process]

Wrede B, Liu P, Wolff JE.
Chemotherapy improves the survival of patients with choroid plexus carcinoma: a meta-analysis of individual cases with choroid plexus tumors.
J Neurooncol. 2007 Jun 19; [Epub ahead of print]
PMID: 17576522 [PubMed - as supplied by publisher]

Yamanaka R Md Phd, Shinbo Y, Sano M, Homma J, Tsuchiya N, Yajima N, Tamura T, Hondoh H, Takahashi H, Morii K, Onda K, Tanaka R.
Salvage therapy and late neurotoxicity in patients with recurrent primary CNS lymphoma treated with a modified ProMACE-MOPP hybrid regimen.
Leuk Lymphoma. 2007 Jun;48(6):1119-1126.
PMID: 17577775 [PubMed - as supplied by publisher]

Yang H, Chopp M, Zhang X, Jiang F, Zhang Z, Kalkanis S, Schallert T.
Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models.
Behav Brain Res. 2007 May 13; [Epub ahead of print]
PMID: 17572515 [PubMed - as supplied by publisher]

Yu JB, Shiao SL, Knisely JP.
A dosimetric evaluation of conventional helmet field irradiation versus two-field intensity-modulated radiotherapy technique.
Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):621-31. Epub 2007 Feb 2.
PMID: 17276616 [PubMed - indexed for MEDLINE]

Zaheer A, Sahu SK, Traynelis VC.
Inhibitors of EGFR Signaling Retard Cytotoxicity of Fenretinide in Rat Gliosarcoma Cells.
Neurochem Res. 2007 Jun 19; [Epub ahead of print]
PMID: 17577665 [PubMed - as supplied by publisher]

Zeng J, Liu H, Song Y.
[Total spondylectomy and reconstruction for thoracolumbar spinal tumors with neurological deficit]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 May;21(5):445-8. Chinese.
PMID: 17578278 [PubMed - in process]

Zingler VC, Grau S, Tonn JC, Jahn K, Linn J, Brandt T, Strupp M.
Superficial cerebral and spinal haemosiderosis caused by secondary tethered cord syndrome after resection of a spinal lymphoma.
J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):767-8.
PMID: 17575022 [PubMed - in process]


Children's Corner


Elisabetta Mancini
Nelly coccinella grassottella (Nelly The Chubby Ladybug

English translation by Mariangela Canzi
BrainLife, 23 June 2007

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