BRAINLIFE Brain Tumor Medical Database

Angiogenesis

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Basic Science


Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
Cancer Cell. 2009 Mar 3;15(3):232-9
  Abstract |   Reprint

Hayden EC.
Cutting off cancer's supply lines.
Nature. 2009 Apr 9;458(7239):686-7
  Abstract |   Full Text |   Related articles

Eunok Im, Andrius Kazlauskas
Regulating angiogenesis at the level of PtdIns-4,5-P2
The EMBO Journal (May 17, 2006) 25, 2075–2082; Published online 20 April 2006; doi:10.1038/sj.emboj.7601100
Abstract | News

Loges S, Mazzone M, Hohensinner P, Carmeliet P
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited
Cancer Cell. 2009 Mar 3;15(3):167-70
  Abstract

Jose G. Teodoro, Albert E. Parker, Xiaochun Zhu, Michael R. Green
p53-Mediated Inhibition of Angiogenesis Through Up-Regulation of a Collagen Prolyl Hydroxylase
Science, 18 August 2006:Vol. 313. no. 5789, pp. 968 - 971, DOI: 10.1126/science.1126391


Brain Tumors


Bababeygy SR, Cheshier SH, Hou LC, Higgins DM, Weissman IL, Tse VC
Hematopoietic Stem Cell-Derived Pericytic Cells in Brain Tumor Angio-Architecture
Stem Cells Dev. 2008 Feb 1; [Epub ahead of print]
Abstract

Ilhan A, Gartner W, Neziri D, Czech T, Base W, Hörl WH, Wagner L
Angiogenic factors in plasma of brain tumour patients
Anticancer Res. 2009 Feb 1;29(2):731-6
  Abstract |   Full Text |   Reprint

Kim WY, Lee HY
Brain angiogenesis in developmental and pathological processes: mechanism and therapeutic intervention in brain tumors
FEBS J. 2009 Sep;276(17):4653-64
  Abstract |   Full Text |   Reprint

Santarelli JG, Udani V, Yung YC, Cheshier S, Wagers A, Brekken RA, Weissman I, Tse V.
Incorporation of bone marrow-derived Flk-1-expressing CD34+ cells in the endothelium of tumor vessels in the mouse brain.
Neurosurgery. 2006 Aug;59(2):374-82
Abstract

Siva K, Venu P, Mahadevan A, S K S, Inamdar MS.
Human BCAS3 Expression in Embryonic Stem Cells and Vascular Precursors Suggests a Role in Human Embryogenesis and Tumor Angiogenesis
PLoS ONE. 2007 Nov 21;2(11):e1202
  Full Text |   Reprint

Zagzag D, Friedlander DR, Margolis B, Grumet M, Semenza GL, Zhong H, Simons JW, Holash J, Wiegand SJ, Yancopoulos GD
Molecular events implicated in brain tumor angiogenesis and invasion
Pediatr Neurosurg. 2000 Jul;33(1):49-55


Glioblastoma


Chen Z, Htay A, Santos WD, Gillies GT, Fillmore HL, Sholley MM, Broaddus WC
In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells
J Neurooncol. 2008 Nov 28;. [Epub ahead of print]
  Abstract

Falchetti ML, Mongiardi MP, Fiorenzo P, Petrucci G, Pierconti F, D'Agnano I, D'Alessandris G, Alessandri G, Gelati M, Ricci-Vitiani L, Maira G, Larocca LM, Levi A, Pallini R
Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts
Int J Cancer. 2007 Nov 20; [Epub ahead of print]
Abstract

Greenfield JP, Jin DK, Young LM, Christos PJ, Abrey L, Rafii S, Gutin PH
Surrogate markers predict angiogenic potential and survival in patients with glioblastoma multiforme
Neurosurgery. 2009 May;64(5):819-26;
  Abstract

He H, Niu CS, Li MW.
Correlation between glioblastoma stem-like cells and tumor vascularization.
Oncol Rep. 2011 Oct 3;. [Epub ahead of print]
  Abstract |   Reprint |   Related articles

Kofman AV, Abounader R.
When tumor cells make blood vessels: implications for glioblastoma therapy.
Future Oncol. 2011 Jul;7(7):841-3.
  Abstract |   Reprint |   Related articles

Philip Kunkel, Ulrike Ulbricht, Peter Bohlen, Marc A. Brockmann, Regina Fillbrandt, Dimitrios Stavrou, Manfred Westphal and Katrin Lamszus
Inhibition of Glioma Angiogenesis and Growth in Vivo by Systemic Treatment with a Monoclonal Antibody against Vascular Endothelial Growth Factor Receptor-2
Cancer Research 61, 6624-6628, September 15, 2001. (PDF Full Text)

Masashi Narazaki, Giovanna Tosato
Tumor Cell Populations Differ in Angiogenic Activity: A Model System for Spontaneous Angiogenic Switch Can Tell Us Why
JNCI Journal of the National Cancer Institute 2006 98(5):294-295
  Full Text |   Reprint

George N. Naumov, Elise Bender, David Zurakowski, Soo-Young Kang, David Sampson, Evelyn Flynn, Randolph S. Watnick, Oddbjorn Straume, Lars A. Akslen, Judah Folkman, Nava Almog
A Model of Human Tumor Dormancy: An Angiogenic Switch From the Nonangiogenic Phenotype
Journal of the National Cancer Institute, Vol. 98, No. 5, 316-325, March 1, 2006
Abstract | Full Text | Reprint | News

Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, Inoue M, Bergers G, Hanahan D, Casanovas O.
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
Cancer Cell. 2009 Mar 3;15(3):220-31
  Abstract |   Full Text |   Reprint

Rose SD, Aghi MK.
Mechanisms of evasion to antiangiogenic therapy in glioblastoma.
Clin Neurosurg. 2010;57:123-8.
  Abstract |   Reprint |   Related articles

Rubenstein JL, Kim J, Ozawa T, Zhang M, Westphal M, Deen DF, Shuman MA
Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption
Neoplasia. 2000 Jul-Aug;2(4):306-14

Tuettenberg J, Grobholz R, Seiz M, Brockmann MA, Lohr F, Wenz F, Vajkoczy P.
Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy
J Cancer Res Clin Oncol. 2009 Mar 10. [Epub ahead of print]°
  Abstract

Yao XH, Ping YF, Chen JH, Chen DL, Xu CP, Zheng J, Wang JM, Bian XW.
Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
J Neurooncol. 2007 Jul 5; [Epub ahead of print]
PMID: 17611713 [PubMed - as supplied by publisher]


Gliomas


Dong J, Zhao Y, Huang Q, Fei X, Diao Y, Shen Y, Xiao H, Zhang T, Lan Q, Gu X.
Glioma Stem/Progenitor Cells Contribute to Neovascularization via Transdifferentiation
Stem Cell Rev. 2010 Aug 10;. [Epub ahead of print]
  Abstract

Folkins C, Shaked Y, Man S, Tang T, Lee CR, Zhu Z, Hoffman RM, Kerbel RS
Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1
Cancer Res. 2009 Sep 15;69(18):7243-51. Epub 2009 Sep 8.
  Abstract

Hong TM, Teng LJ, Shun CT, Peng MC, Tsai JC
Induced interleukin-8 expression in gliomas by tumor-associated macrophages
J Neurooncol. 2009 Jan 21. [Epub ahead of print]
  Abstract

J. Holash, P. C. Maisonpierre, D. Compton, P. Boland, C. R. Alexander, D. Zagzag, G. D. Yancopoulos, S. J. Wiegand
Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF
Science, Vol 284, CNO 5422, 1994-1998 , 18 June 1999. (PDF Full Text)

Lamszus K, Kunkel P, Westphal M
Invasion as limitation to anti-angiogenic glioma therapy
Acta Neurochir Suppl. 2003;88:169-77

Peoch M, Farion R, Hiou A, Le Bas JF, Pasquier B, Remy C
Immunohistochemical study of VEGF, angiopoietin 2 and their receptors in the neovascularization following microinjection of C6 glioma cells into rat brain
Anticancer Res. 2002 Jul-Aug;22(4):2147-51

Zagzag D, Amirnovin R, Greco MA, Yee H, Holash J, Wiegand SJ, Zabski S, Yancopoulos GD, Grumet M
Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis
Lab Invest. 2000 Jun;80(6):837-49


Glioma (High-Grade)


Castellino RC, Durden DL
Mechanisms of Disease: the PI3K-Akt-PTEN signaling node-an intercept point for the control of angiogenesis in brain tumors
Nat Clin Pract Neurol. 2007 Dec;3(12):682-93
Abstract

Suash Sharma, Mehar C. Sharma, Deepak Kumar Gupta and Chitra Sarkar
Angiogenic patterns and their quantitation in high grade astrocytic tumors
J Neurooncol. 2006 Aug;79(1):19-30. Epub 2006 Jun 29.
Abstract

Takano S, Yamashita T, Ohneda O.
Molecular therapeutic targets for glioma angiogenesis
J Oncol. 2010;2010:351908. Published online 2010 April 18
  Abstract |   Full Text |   Reprint


Neuroblastoma


Eugene S. Kim, Anna Serur, Jianzhong Huang, Christina A. Manley, Kimberly W. McCrudden, Jason S. Frischer, Samuel Z. Soffer, Laurence Ring, Tamara New, Stephanie Zabski, John S. Rudge, Jocelyn Holash, George D. Yancopoulos, Jessica J. Kandel and Darrell J. Yamashiro
Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma
PNAS, August 20, 2002; Vol. 99, No. 17, 11399-11404. (PDF Full Text)


Tumors


Belo AV, Barcelos LS, Teixeir MM, Ferreira MA, Andrade SP.
Differential effects of antiangiogenic compounds in neovascularization, leukocyte recruitment, VEGF production, and tumor growth in mice.
Cancer Invest. 2004;22(5):723-9

Holash J, Wiegand SJ, Yancopoulos GD
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
Oncogene. 1999 Sep 20;18(38):5356-62


Wilms Tumor


Huang J, Frischer JS, New T, Kim ES, Serur A, Lee A, Kadenhe-Chiwishe A, Pollyea DA, Yokoi A, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ
TNP-470 promotes initial vascular sprouting in xenograft tumors
Mol Cancer Ther. 2004 Mar;3(3):335-43

 

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